Digital Commons Network^™

Trf-Bwm-Neutrosophic-Topsis Strategy Under Svns Environment Approach And Its Application To Select The Most Effective Water Quality Parameter Of Aquaponic System, Pragnaleena Debroy, Priyanka Majumder, Surapati Pramanik, Lalu Seban

Neutrosophic Sets and Systems

The rapid emergence of aquaponics presents a promising solution for food production in arid regions, heavily reliant on maintaining optimal water quality parameters for overall success. However, monitoring and controlling these parameters can be complex and costly, involving numerous sensors and actuators. Focusing on the most significant parameter for fish growth could alleviate some of this complexity and promote sustainability by ensuring a balanced system. This study introduces a novel fuzzy-based Multiple Criteria Decision Making (MCDM) methodology, combining Trapezoidal Fuzzy with the Best Worst Method (BWM) and Neutrosophic-TOPSIS strategy, to identify the primary water quality parameters impacting fish growth. Through …

Harmonic Mean Operator Based Madm-Strategy Under Svpn-Set Environment, Bimal Shil, Suman Das, Rakhal Das, Binod Chandra Tripathy

Neutrosophic Sets and Systems

By using single-valued pentapartitioned neutrosophic set (briefly SVPN-set), one can express uncertainty events having incomplete, indeterminate, and erroneous information in practical applications. This study's primary goal is to present a multi-attribute decision-making (briefly MADM) algorithm that operates in the SVPN-set environment using the notion of single-valued pentapartitioned neutrosophic harmonic mean (briefly SVPNHM) operator and single-valued pentapartitioned neutrosophic weighted harmonic mean (briefly SVPNWHM) operator. Further, we provide a numerical illustration here like, “Location Selection for Installation of Outdoor Air Purifier” to validate the effectiveness and rationality of the proposed MADM algorithm.

Continuous Flow Injection Analysis Method For The Determination Of A Drug Diphenhydramine Hydrochloride By Using Phosphomolybdic Acid, Muntadhar M. Jabbar, Elham N. Mezaal

Baghdad Science Journal

The study presented a new method for determining diphenhydramine hydrochloride (DPH) in its pure form and some pharmaceutical preparations, within CFIA technique. The method is simple, fast, sensitive, easy to operate, and of a low cost. It is based on the reaction of DPH with phosphomolybdic acid (PMA), in aqueous media, forming a white, slightly yellowish precipitate. The precipitate formed was studied using an Ayah 6S×1-ST-2D solar cell CFI analyzer, by the reflection of incident light off the surfaces of the deposited particles at (0–180°), expressed as the response measured in (mV) . Some chemical and physical variables were studied …

In Vivo Study The Cytogenetic Effect Of Ammi Majus Methanolic Extract On Mitotic Index, Micronucleus Formation And Dna Damage On Mitoxantrone Treated Albino Male Mice, Ruqaya Mohammed Al-Ezzy, Maysaa Hamid Ahmed, Hadeel Mohamed Khalaf

Baghdad Science Journal

Medicinal plants or their secondary metabolites have shown different biological effects with a wide range of pharmacological properties; for instance, immune stimulator, anti-bacterial, anti-viral, anti-inflammatory, anti-oxidant, anti-mutagenic, anticancer, hepatoprotective, and many other properties. One of these medicinal plants is Ammi majus. The purpose of this research was to evaluate the cytogenetic impact of a methanolic extract of the Ammi majus plant on micronucleus formation, mitotic index and DNA damage in mice that had been given intraperitoneally mitoxantrone medicine (anticancer drug). Mice were divided into four groups, each group consisting of four mice: group I (positive control), mice treated with 0.008 …

Grhpr Gene Variations In Iraqi Patients Infected With Calcium Oxalate Kidney Stones, Duha Abed Almuhssen Muzahim Alzubaidy, Luma Hassan Alwan Al Obaidy

Baghdad Science Journal

The alterations in glyoxylate reductase and hydroxy-pyruvate reductase concentrations in the sera and the genetic alterations associated with calcium oxalate kidney stones in Iraqi patients were not studied previously so this study aimed to focus on these points. This study included 80 subjects; they were 50 patients with calcium oxalate stones compared to 30 apparently healthy controls. Biochemical investigations for kidney functions (creatinine, urea, and uric acid), were performed on the sera of both groups. Also, complete blood count, random blood sugar, and blood group tests. Furthermore, urine had been collected for General Urine Examination to visualize oxalate crystals in …

Evaluation Of Antioxidants, Antibacterial And Antidiabetic Activities Of Aqua-Alcoholic Marjoram Extract, Kadhim K. Ghudhaib, Fayhaa M. Khaleel

Baghdad Science Journal

Plant extracts possess special significance towards human health and vital activities for a wide range of diseases. The current study aims at verifying the presence of active ingredients in marjoram leaves extract, and determining antioxidants, antibacterial and antifungal activities, LD50 and its antidiabetic activity. The active ingredients were qualitatively analyzed by specific test methods. Antioxidant, LD50, antibacterial and antifungal activities were measured by their standard method. The antidiabetic activity was determined by assessed hyperglycemia, hyperlipidemia and liver functions by spectrophotometric methods. The results confirmed the presence of several active components including flavonoids, alkaloids, terpenoids, tannins, and saponins. Also, the results …

Neoantigen-Specific Cytotoxic Tr1 Cd4 T Cells Suppress Cancer Immunotherapy, Hussein Sultan, Yoshiko Takeuchi, Jeffrey P Ward, Naveen Sharma, Tian-Tian Liu, Vladimir Sukhov, Maria Firulyova, Yuang Song, Samuel Ameh, Simone Brioschi, Darya Khantakova, Cora D Arthur, J Michael White, Heather Kohlmiller, Andres M Salazar, Robert Burns, Helio A Costa, Kelly D Moynihan, Yik Andy Yeung, Ivana Djuretic, Ton N Schumacher, Kathleen C F Sheehan, Marco Colonna, James P Allison, Kenneth M Murphy, Maxim N Artyomov, Robert D Schreiber

Faculty, Staff and Student Publications

CD4+ T cells can either enhance or inhibit tumour immunity. Although regulatory T cells have long been known to impede antitumour responses1-5, other CD4+ T cells have recently been implicated in inhibiting this response6,7. Yet, the nature and function of the latter remain unclear. Here, using vaccines containing MHC class I (MHC-I) neoantigens (neoAgs) and different doses of tumour-derived MHC-II neoAgs, we discovered that whereas the inclusion of vaccines with low doses of MHC-II-restricted peptides (LDVax) promoted tumour rejection, vaccines containing high doses of the same MHC-II neoAgs (HDVax) inhibited rejection. Characterization of the inhibitory cells induced by HDVax identified …

Investigation Of The Pangas (Pangasianodon Hypophthalmus) Cultivation Sustainability In Cages At The Ratargul Freshwater Swamp Forest Of Bangladesh, Mrityunjoy Kunda, Md. Abu Kawsar, Diponkor Adikari, Sakib Tahmid Rishan, Ahmed Harun-Al-Rashid, Debasish Pandit

School of Integrative Biological & Chemical Sciences Faculty Publications

Determining the most appropriate stocking density for a specific fish species in an ambient condition is essential for successful cage aquaculture in terms of profitability which is mainly governed by growth. The current study was conducted to ascertain which stocking density gives the best result of widely cultured species in cage aquaculture, pangas (Pangasianodon hypophthalmus), at swamp forest environment of Ratargul Freshwater Swamp Forest, Bangladesh in terms of growth, production and economic return. Fish were reared for 93 days at three stocking densities, namely 30, 40 and 50 fish/m3 which were denoted as FSD30, FSD40 and FSD50, respectively, …

Sex-Dependent Differences In Vulnerability To Early Risk Factors For Posttraumatic Stress Disorder: Results From The Aurora Study, Stephanie Haering, Antonia V. Seligowski, Sarah D. Linnstaedt, Vasiliki Michopoulos, Stacey L. House, Francesca L. Beaudoin, Xinming An, Thomas C. Neylan, Robert A. Swor

Articles

No abstract provided.

Harry Potter And The Immersive Space: A Rhetorical Analysis Of The Wizarding World Of Harry Potter, Kendra Bolin

Electronic Theses and Dissertations

The ability of humans to share stories has changed over time. From myths shared around a campfire to the introduction of cinema, we can now tell massive, immersive stories on an epic scale. One example of this is the storytelling present in theme parks. Present-day theme parks are continuously growing and expanding each year both in size and attendance. The continued success of these theme parks and the rhetorical influences of their audiences is a cultural phenomenon that deserves rhetorical scrutiny. My analysis looks at how one theme park, the Wizarding World of Harry Potter in Orlando, Florida, immerses guests …

Cerebellar Functions Beyond Movement And Learning, Linda H Kim, Detlef H Heck, Roy V Sillitoe

Duncan NRI Faculty and Staff Publications

The cerebellum has a well-established role in controlling motor functions, including coordination, posture, and the learning of skilled movements. The mechanisms for how it carries out motor behavior remain under intense investigation. Interestingly though, in recent years the mechanisms of cerebellar function have faced additional scrutiny since nonmotor behaviors may also be controlled by the cerebellum. With such complexity arising, there is now a pressing need to better understand how cerebellar structure, function, and behavior intersect to influence behaviors that are dynamically called upon as an animal experiences its environment. Here, we discuss recent experimental work that frames possible neural …

Influence Of Stimulation Frequency On Brain-Derived Neurotrophic Factor And Cathepsin-B Production In Healthy Young Adults, Yuichi Nishikawa, Hiroyuki Sakaguchi, Tatsuya Takada, Noriaki Maeda, Allison S. Hyngstrom

Physical Therapy Faculty Research and Publications

Electrical muscle stimulation (EMS) has been shown to stimulate the production of myokines (i.e., brain-derived neurotrophic factor (BDNF)), but the most effective EMS parameters for myokine production have not been fully elucidated. The purpose of this study was to quantify the optimal EMS frequency for stimulating myokine production. This study included sixteen young adults (male, n = 13, age = 27.3 ± 5.5 years). Participants underwent four EMS interventions (20 min each) with the following conditions: (1) 4 Hz, (2) 20 Hz, (3) 80 Hz, and (4) control (no intervention). Blood samples were obtained before and immediately after EMS. For …

Kritisamhita: A Machine Learning Dataset Of South Indian Classical Music Audio Clips With Tonic Classification, Samhita Konduri, Kriti V. Pendyala, Vishnu S. Pendyala

Faculty Research, Scholarly, and Creative Activity

There are currently a limited number of Indian classical music datasets, especially those large enough and with useful annotations, particularly the subtler ones, such as the tonic, for training classification or prediction models. The dataset described in this paper is created with useful tonic annotations, to fill this gap. The tonic pitch, or base pitch, plays an important role in music, so much so that it is sometimes called the keynote. The vocalists and the accompanying instrumental ensemble are fine-tuned to this keynote to render the composition. The first and second authors of this paper, who are vocalists themselves, recorded …

Experimental Investigation Of The Suitability Of Soybean-Derived Surfactant (Sods) In Gas Well Deliquification, Abiodun Gbadegesin Adeyemi

Theses and Dissertations

Gas well deliquification is a crucial process in the oil and gas industry, focused on maintaining or restoring production rates by removing liquids that impede gas flow. This is a recurring challenge that is prominent in many gas wells across North Dakota. Surfactants play a vital role in this process by altering the interfacial tension between gas and liquid phases, alleviating liquid accumulation in these wells. However, due to their high production costs, non-biodegradability, and toxicity, the use of synthetic surfactants has raised environmental concerns. The pursuit of sustainable and environmentally friendly alternatives has led to the exploration of natural …

Transcriptional Landscape Of Foxp3+ Regulatory T Cells Under Mitochondrial Oxidative Stress: Implications For Inflammaging, Jappreet Singh Gill

Theses and Dissertations

This thesis explores the intricate relationship between mitochondrial oxidative stress and the function of FOXP3+ regulatory T cells (Tregs), highlighting their essential roles in the aging immune system and the development of age-related diseases. The study delves into how mitochondrial impairments within Tregs contribute to widespread inflammation leading to pathological aging. One key analysis shows that mitochondrial oxidative stress undermines Treg functionality, intensifying inflammatory responses and increasing frailty in older adults. This dysfunction is associated with elevated inflammatory markers and presents a potential target for therapeutic interventions aimed at restoring mitochondrial health to alleviate these impacts. Another significant discovery connects …

Population Pharmacokinetic Modelling And Simulation Of Tranexamic Acid In Adult Trauma Patients, Gideon Stitt, Philip C Spinella, Grant V Bochicchio, Ian Roberts, Kevin J Downes, Athena F Zuppa

2020-Current year OA Pubs

AIMS: The aim of this study is to describe the disposition of tranexamic acid (TXA) in adult trauma patients and derive a dosing regimen that optimizes exposure based on a predefined exposure target.

METHODS: We performed a population pharmacokinetic (popPK) analysis of participants enrolled in the Tranexamic Acid Mechanisms and Pharmacokinetics in Traumatic Injury (TAMPITI) trial (≥18 years with traumatic injury, given ≥1 blood product and/or requiring immediate transfer to the operating room) who were randomized to a single dose of either 2 or 4 g of TXA ≤2 h from time of injury. PopPK analysis was conducted using nonlinear …

Age-Related Dysregulation Of The Retinal Transcriptome In African Turquoise Killifish, Steven Bergmans, Nicole C L Noel, Luca Masin, Ellen G Harding, Aleksandra M Krzywańska, Julie D De Schutter, Rajagopal Ayana, Chi-Kuo Hu, Lut Arckens, Philip A Ruzycki, Ryan B Macdonald, Brian S Clark, Lieve Moons

2020-Current year OA Pubs

Age-related vision loss caused by retinal neurodegenerative pathologies is becoming more prevalent in our ageing society. To understand the physiological and molecular impact of ageing on retinal homeostasis, we used the short-lived African turquoise killifish, a model known to naturally develop central nervous system (CNS) ageing hallmarks and vision loss. Bulk and single-cell RNA-sequencing (scRNAseq) of three age groups (6-, 12-, and 18-week-old) identified transcriptional ageing fingerprints in the killifish retina, unveiling pathways also identified in the aged brain, including oxidative stress, gliosis, and inflammageing. These findings were comparable to observations in the ageing mouse retina. Additionally, transcriptional changes in …

Translational Approaches To The Neurobiological Study Of Conditional Discrimination And Inhibition: Implications For Psychiatric Disease, Susan Sangha, Jacklynn M. Fitzgerald

Psychology Faculty Research and Publications

There is a growing number of studies investigating discriminatory fear conditioning and conditioned inhibition of fear to assess safety learning, in addition to extinction of cued fear. Despite all of these paradigms resulting in a reduction in fear expression, there are nuanced differences among them, which could be mediated through distinct behavioral and neural mechanisms. These differences could impact how we approach potential treatment options in clinical disorders with dysregulated fear responses. The objective of this review is to give an overview of the conditional discrimination and inhibition findings reported in both animal models and human neuropsychiatric disorders. Both behavioral …

Impact Of Thermal-Hydric Stress Of Physiological Performance And Mating Behavior Of Fiddler Crabs, Talene G. Yeghissian

Dissertations

Fiddler crabs live on the edge of their thermal tolerance limits, balancing the need to thermoregulate with the need to mate. Previous research suggests that increased temperature reduces fiddler crab surface activity time, thus decreasing mating opportunities, throughout the range species with greatest impacts to low latitude populations. The less studied missed mating opportunities associated with behavioral compensation for thermal stress are crucial to understanding species vulnerability to climate change. In this dissertation, I describe a combination of experimental and observational approaches in the field and in the laboratory to investigate the physiological and behavioral responses of fiddler crabs to …

The Interactions Between Drought Tolerant Corn Hybrids And Plant Water-Stress On Weeds And Their Host Capability For Spider Mites, Mercy Adhiambo Odemba

All Graduate Theses and Dissertations, Fall 2023 to Present

With climate change, it is predicted that more frequent high temperatures and drought severity will lead to an increase in damage caused by pests that thrive under these conditions. Spider mite outbreaks, for example, are associated with plant waterstress and there is evidence that some weeds are more resilient and adapted to drought than some crops, leading to major concerns for the management of these two pest types. Weeds directly compete with crops for limited resources, but what is unclear is which weeds harbor spider mites and whether they exacerbate the impact of spider mites on corn crops under water-stressed …

Sparks, Belonging, And Relationships: High School Teachers' Use Of Developmental Context To Engage Students In Career Pathways, Dave Francis

All Graduate Theses and Dissertations, Fall 2023 to Present

The 4-H Thriving Model outlines how a foundation for youth sparks, belonging, and relationships can lead to short and long-term outcomes. This study explored how high school teachers in Utah integrate the elements of the foundation of the 4-H Thriving Model in environmental science and natural resources management classroom teaching. A mixed method of interviews and surveys was used to understand teaching practices. Teachers described helping students discover their interests (sparks), nurturing these interests, and linking them to careers using methods like guest speakers, field trips, contests, and student presentations. They also worked on creating a sense of belonging in …

Citizen Science Project On Urban Canids Provides Different Results From Camera Traps But Generates Interest And Revenue, Neville F. Taraporevala

All Graduate Theses and Dissertations, Fall 2023 to Present

As more people live in cities, wildlife increasingly encounters people. Coyotes (Canis latrans) and red foxes (Vulpes vulpes) are two carnivores that have easily adapted to urban environments causing them to come into conflict with people and their pets. Citizen science, where members of the community aid scientists in the collection of data, has emerged as a low-cost method of studying these species that can provide benefits to management agencies but may provide different results than traditional methods. We analyzed data collected by citizen scientists and data collected via motion-triggered camera traps to see how each …

Working Together For Working Lands: Knowledge Braiding And Adaptive Capacity At The Confluence Of Rangelands, Climate Adaptation, And Watershed Stewardship, William Wesley Munger

All Graduate Theses and Dissertations, Fall 2023 to Present

Working lands are a mosaic that hold critical opportunities for biodiversity, rural community wellbeing, and climate change adaptation. This landscape mosaic is made up of public lands, tribal lands, and private ranches, farms, and forests. The current era of ecological restoration and climate adaptation requires engaging in working lands conservation because the most promising strategies require working across multiple ownership boundaries. This dissertation argues that supporting working lands conservation, climate adaptation, and ecological restoration is a joint venture. Building adaptive capacity for climate change involves both social and ecological components. Adaptive capacity consists of building social collaborative capacity and ecological …

Comparative Morphology And Development Of The Trigeminally Innervated Infrared-Imaging System In Boas And Pythons, Helen Bond Plylar

All Graduate Theses and Dissertations, Fall 2023 to Present

Boas and pythons use specialized sense organs called pit organs to detect radiant heat. Pit organs in these lineages occur in paired arrays along the upper and lower jaws and are served by the trigeminal nerve (the fifth cranial nerve and one of the largest). Information from the pit organs travels via branches of the trigeminal to the brain and ultimately is processed in the optic tectum, along with information from the visual system. That means these snakes effectively “see” heat. While studies of the pitviper infrared-imaging system are numerous, very few studies of this system in pythons or boas …

Effect Of Nutrient And Temperature Conditions On The Production Of Microcystins From Cyanobacteria In Pineview Reservoir, Brent G. Jacobson

All Graduate Theses and Dissertations, Fall 2023 to Present

Cyanobacteria, sometimes known as harmful algae, are an aquatic bacteria capable of producing toxic compounds. Cyanobacteria are found worldwide in both saltwater and freshwater environments. Depending on the environment, toxic cyanobacteria species can outcompete other aquatic species, grow in large numbers, and produce these toxic compounds. Further understanding of what environmental conditions promote the production of these harmful bacteria and toxins is needed to protect and inform the public.

In order to understand why cyanobacteria produce toxins in certain environments, samples containing cyanobacteria were taken from a Pineview Reservoir, Utah, and cultured at the Utah State Water Research Laboratory. Cyanobacteria …

Examining The Influence Of Pedagogical Content Knowledge, Job Satisfaction, And Professional Identity On The Turnover Intentions Of Traditionally Certified And Alternatively Certified School-Based Agricultural Education Teachers: A National Study, Matthew J. Wood

All Graduate Theses and Dissertations, Fall 2023 to Present

Recruitment and retention of agriculture teachers has been an ongoing challenge within education, with schools struggling to attract and keep qualified teachers. Research has explored many factors—including job satisfaction, work-life balance, administrative support, and professional development opportunities—to uncover the complex roots of teacher turnover. Despite these efforts, the cycle of recruiting and sustaining passionate and competent agriculture teachers remains a significant hurdle. A clear and comprehensive understanding of the factors that influence teacher turnover intentions is needed. This research aimed to explore the factors that influence the turnover intentions of SBAE teachers by licensure type. The Four Capital Theory of …

An Examination Of Traumatic Brain Injury And Genes For Neurotrophins And Apolipoprotein E In Predicting Cognitive Function In Older Adults: The Cache County Study, Mikaela A. Drewel

All Graduate Theses and Dissertations, Fall 2023 to Present

Recovery from a traumatic brain injury (TBI) is influenced by a wide array of factors including age at incidence, number, and severity as well as genetic factors, some of which exhibit sex-dependent effects. This study examines how TBI history influences rate of cognitive decline in older adults, exploring the characteristics of TBI (e.g., number, severity, and timing) as predictors and interactions of TBI history with genetic variants suspected to play a role in brain health and late-life cognitive functioning. These genes include the Apolipoprotein E (APOE) as well as brain derived neurotrophic factor (BDNF) and its receptors. This study analyzed …

The Protagonist Of Contemporary And Emerging Nanotechnology-Based Theranostics And Therapeutic Approaches In Reshaping Intensive Care Unit, Ling Xie, Yun Chen

Saudi Medical Journal

To maintain a clean and hygienic environment in the intensive care unit (ICU) is crucial for ensuring patient safety, preventing infections, and reducing healthcare-associated complications. With the increasing prevalence of infections and the emergence of viral and bacterial resistance to standard antiseptics, there is a pressing need for innovative antiseptic solutions. Nanotechnology is increasingly being employed in medicine, particularly focusing on mitigating the activities of various pathogens, including those associated with hospital-acquired infections. This paper explores the current impact of nanotechnology, with a particular focus on bacterial infections and SARS-CoV-2, which significantly strain healthcare systems, and then discusses how nanotechnology …

Identification Of Effective Diagnostic Genes And Immune Cell Infiltration Characteristics In Small Cell Lung Cancer By Integrating Bioinformatics Analysis And Machine Learning Algorithms, Yinyi Chen, Kexin Han, Yanzhao Liu, Qunxia Wang, Yang Wu, Simei Chen, Jianlin Yu, Yi Luo, Liming Tan

Saudi Medical Journal

Objectives: To identify potential diagnostic markers for small cell lung cancer (SCLC) and investigate the correlation with immune cell infiltration. Methods: GSE149507 and GSE6044 were used as the training group, while GSE108055 served as validation group A and GSE73160 served as validation group B. Differentially expressed genes (DEGs) were identified and analyzed for functional enrichment. Machine learning (ML) was used to identify candidate diagnostic genes for SCLC. The area under the receiver operating characteristic curves was applied to assess diagnostic efficacy. Immune cell infiltration analyses were carried out. Results: There were 181 DEGs identified. The gene ontology analysis showed that …

Microbiome Assembly And Function In The Solitary Mason Bee, Osmia Lignaria (Megachilidae), Bailey Crowley

All Graduate Theses and Dissertations, Fall 2023 to Present

Animal-microbe interactions can influence host biology, ecology, and evolution. The assembly and function of microbes found within animal hosts oftentimes depends on which species are involved. Advances in sequencing technologies have permitted the exploration of host-microbe interactions in a variety of animals, including bees. Early research aimed at understanding the microbiomes of social bees, such as honey bees and bumble bees, found that microbes prevent the spoilage of stored pollen, breakdown indigestible nutrients into smaller molecules available for uptake by the host, and also protect the host from pathogens. When environmental stressors, such as increased temperatures, disrupt the microbiome, the …