Digital Commons Network^™

Oh My God, Cape Cod, Hana Huebler

PoemMemoirStory (literary magazine)

pp. 90-99

Guernica, Morgan Finn

PoemMemoirStory (literary magazine)

pp. 23-28

Pms 16 (Complete Issue), Poemmemoirstory Staff

PoemMemoirStory (literary magazine)

No abstract provided.

An Advanced Way To Ensure Data Quality Of Retrieval Augmented Generation (Rag) Pipelines, Kautuk Pandey

Defensive Publications Series

The present disclosure provides a method of an automated way to calculate and evaluate quality factor of metadata provided to Retrieval Augmented Generation (RAG) pipelines for ensuring data quality of RAG pipelines used in LLM apps for Generative Artificial Intelligence (AI) application. The method includes capturing metadata of vectors/ embeddings while receiving vectors/ embeddings, applying Anomaly Detection models to generate threshold for expected metadata, applying quality score based filtering based on metadata on the Approximate Nearest Neighbour (ANN) search while generating output response in response to user query, providing output response based on the filtered vectors

Counseling In Virtual Spaces And Into The Metaverse: A Framework For Reflection, Conversation, And Future Scholarship, Staci Hayes, Yahyahan Aras, Kathy Caputo, James Hoag, Lindsay Ibos, Sania Khan, Kelly Smith

Journal of Technology in Counselor Education and Supervision

Given the success of Virtual Reality (VR) in the gaming community and strides in mental health, both VR and the Metaverse provide limitless opportunities and possibilities in the field of counseling. This article aims to provide important definitions, an overview of the use of VR in clinical counseling, clinical supervision, counselor education and its potential emergence into the Metaverse. Implications are presented in hopes of prompting conversation on how we may accept technological and cultural shifts and remain true to our counseling roots. Specifically, how to maximize the potential benefits with counseling specific rationale and address the limitations and potential …

Spartan Daily, September 11, 2024, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2024

Volume 163, Issue 8

Brain-Wide Projections Of Mouse Dopaminergic Zona Incerta Neurons, Bono, Kenichiro Negishi, Yasmina Dumiaty, Monica Ponce, Titilayo Akinbode, Kayla Baker, C. Duncan Spencer, Elizabeth Mejia, Marina Guirguis, Alex Herbert, Arshad Khan, Melissa Chee

Departmental Papers (Biology)

No abstract provided.

¡Juntos Al Éxito! #27 - Path To R1, The University Of Texas Rio Grande Valley. College Of Sciences, Teresa Patricia Feria-Arroyo, Can Saygin, Thomas B. Spencer

¡Juntos al Éxito! - Empowering Excellence Program Recordings

In this session speakers discussed R1 status and Research Operations.

Spectrum, Volume 53, Issue 1, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: Notre Dame Prep of Sacred Heart University - New Dorms Open for Freshmen, -“Paws and Relax” with Scarlett the Therapy Doodle - SHU’s Suicide Prevention Week - 50 First Days of Arts & Entertainment - Pickleball’s Campus Takeover

Efficacy And Mechanism Of Action Of Cd40 Ligand And Interleukin-12 Plasmid Electroporation Intratumoral Immunotherapy, Gregory W. Ho

Dartmouth College Ph.D Dissertations

Cancer is a disease in which normal cells have become altered such that they divide uncontrollably, ultimately leading to tissue destruction. While efficacious cancer therapies have been developed in recent decades, many of them come with drawbacks such as cost and systemic toxicity. Additionally, solid tumors remain difficult to treat due to the immunosuppressive tumor microenvironment. Intratumoral immunotherapy (ITIT) strives to generate effective antitumor immunity by directly administering immunostimulatory adjuvants into tumors to reverse local tumor-mediated immune suppression and generate systemic immune responses against metastases. Intratumoral immunotherapy utilizing in vivo expression of interleukin-12 (IL-12) via plasmid electroporation has been investigated …

Constitutive Upregulation Of Transcription Factors Underlies Permissive Bradyzoite Differentiation In A Natural Isolate Of Toxoplasma Gondii, Jing Xia, Yong Fu, Wanyi Huang, Taher Uddin, L David Sibley

2020-Current year OA Pubs

UNLABELLED:

IMPORTANCE:

Office Of Research, Economic Engagement And Outreach Update, September 11, 2024, Office Of Research, Economic Engagement And Outreach

Office of Research, Economic Engagement and Outreach

No abstract provided.

Life In The Margins: The Effect Of Immersion/Emersion And Tidal Cycle On The North Atlantic Limpet Patella Vulgata Protein Synthesis Rates, Ignacio Alvarez-Cienfuegos, Benjamin Ciotti, Richard Billington, Paul Sutton, Keiron Fraser

School of Biological and Marine Sciences

Biological processes in intertidal species follow tidal rhythms that enhance survival and fitness. Whereas tidal effects on behaviour and metabolic rates have been widely studied, impacts on other key process such as protein synthesis are still poorly understood. To date, no studies have examined the effect of immersion/emersion and tidal cycles on protein synthesis rates (k _s). Patella vulgata is an intertidal limpet present in North-Eastern Atlantic rocky shores from high to low shore. Previously reported P. vulgata respiration and heart rate measurements suggest aerobic metabolism is maintained during emersion and growth rates increase from high to low shore, …

Batf Is A Major Driver Of Nk Cell Epigenetic Reprogramming And Dysfunction In Aml, Bijender Kumar, Anand Singh, Rafet Basar, Nadima Uprety, Ye Li, Huihui Fan, Ana Karen Nunez Cortes, Mecit Kaplan, Sunil Acharya, Hila Shaim, Anna C Xu, Manrong Wu, Emily Ensley, Dexing Fang, Pinaki P Banerjee, Luciana Melo Garcia, Silvia Tiberti, Paul Lin, Hind Rafei, Maliha Nuzhat Munir, Madison Moore, Mayra Shanley, Mayela Mendt, Lucila N Kerbauy, Bin Liu, Alexander Biederstädt, Elif Gokdemir, Susmita Ghosh, Kiran Kundu, Francia Reyes-Silva, Xin Ru Jiang, Xinhai Wan, April L Gilbert, Merve Dede, Vakul Mohanty, Jinzhuang Dou, Patrick Zhang, Enli Liu, Luis Muniz-Feliciano, Gary M Deyter, Abhinav K Jain, Juan Jose Rodriguez-Sevilla, Simona Colla, Guillermo Garcia-Manero, Elizabeth J Shpall, Ken Chen, Hussein A Abbas, Kunal Rai, Katayoun Rezvani, May Daher

Faculty, Staff and Student Publications

Myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) belong to a continuous disease spectrum of myeloid malignancies with poor prognosis in the relapsed/refractory setting necessitating novel therapies. Natural killer (NK) cells from patients with myeloid malignancies display global dysfunction with impaired killing capacity, altered metabolism and exhausted phenotype at the single cell transcriptomic and proteomic levels. In this study we identified that this dysfunction was mediated through a crosstalk between NK cells and myeloid blasts necessitating cell-cell contact. NK cell dysfunction could be prevented by targeting the αvβ integrin/TGF-β/SMAD pathway but, once established, was persistent due to profound epigenetic reprogramming. …

Investigating The Inhibitory Effect Of Β-Rb1-Lip On Lipid Droplet Accumulation In 3t3-L1 Adipocytes, You Xiaoyan, Liu Hui, Duan Xu, Chen Yue

Food and Machinery

[Objective] β-Sitosterol-modified ginsenoside Rb₁ liposomes （β-Rb₁-Lip） were prepared to reduce the degradation of Rb₁ and enhance the lipid-lowering effects of ginsenoside Rb1. [Methods] β-sitosterol-modified ginsenoside Rb₁ liposomes were prepared by the thin-film hydration method. The biosafety of the liposomes was assessed using the MTT assay. The inhibition of lipid droplet accumulation in 3T3-L1 adipocytes by β-Rb₁-Lip was investigated using Oil Red O staining and triglyceride （TG） content measurement with an enzyme-linked immunosorbent assay. [Results] The prepared β-Rb₁-Lip liposomes had an encapsulation efficiency of 83.74% and …

Comparative Analysis Of Optical Characterization Parameters For Tea Oil Forensics, Guan Jinwei, Li Dapeng, Gong Zhongliang, Liu Qiang, Jiang Han

Food and Machinery

[Objective] In order to compare the ability of optical characteristic parameters [absorption coefficient （μ_a） and approximate scattering coefficient （μ′_s）] to identify adulterated tea oil and to explore the enhancement effect of the combination of extraction methods on the model to achieve a faster and more accurate identification of different kinds of adulterated oils. [Methods] In this study, vegetable oils were used as experimental materials to prepare adulterated tea oils with different mass fractions. Different preprocessing methods were used to preprocess the optical characteristic parameter data, followed by feature band extraction and subsequent establishment …

Study On Simultaneous Determination Of Arsenic Speciation And Selenium Speciation In Selenium-Rich Foods By Hplc-Icp-Ms, Feng Hao, Su Ying, Geng Yawen, Hu Jiayong, Zhang Tao, Lin Jin

Food and Machinery

[Objective] A method for the simultaneous determination of arsenate [As(Ⅲ)], Arsenate [As(Ⅴ)], monomethylarsenate (MMA), dimethylarsenate (DMA), Arsine betaine (AsB), methyl-selenocysteine (MeSeCys) and selenomide in food was developed by high performance liquid phase inductively coupled plasma mass spectrometry (HPLC-ICP-MS), and a total of 10 kinds of arsenic and selenium element forms of As and Se, including acid (SeMet), selenocysteine (SeCys2), selenite [Se(Ⅳ)] and selenate \. [Methods] Taking selenium rich rice as the research object, the best extraction method was determined by comparing different extraction methods and different kinds of enzymes. Moreover, different chromatographic columns, mobile phase composition, mobile phase pH, mobile …

Numerical Simulation And Validation Of Ice Filling Process For Ice Slurry Precooling Box Packaging Of Broccoli, Li Gan, Wang Qing, Lu Lixin, Pan Liao

Food and Machinery

[Objective] In order to solve the problem of uniformity of ice crystal distribution in the process of ice slurry filling. [Methods] Taking broccoli as the research object, the physical model of packing broccoli in carton was established, and the effects of ice filling speed and ice filling Angle on ice crystal distribution uniformity during the ice filling process were analyzed by CFD simulation, so as to determine appropriate ice filling process parameters. [Results] The ice-filling speed and filling angle significantly impact the uniformity of ice crystal distribution. Both excessively low and high ice-filling speeds were detrimental to achieving uniform ice …

Effect Of High Fat, High Fat And High Fructose Diet On Hyperuricemia In Rats, Che Yingjuan, Chen Yan, Chen Tingting, Luo Shunjing, Liu Chengmei

Food and Machinery

[Objective] This study aimed to investigate the effects of high fat diet and high fat and high fructose diet on uric acid level and liver and kidney function in hyperuricemia (HUA) rats. [Methods] 24 rats were randomly divided into control group, model group, high-fat diet group and high-fat and high-fructose diet group. All rats were fed with the corresponding diets, except the control group, 500 mg/kg potassium oxazinate and 100 mg/kg adenine per day. After 6 weeks, serum biochemical indexes such as uric acid and creatinine were determined, and pathological examination of kidney and liver was performed. [Results] The uric …

Preparation Technology Of Tangerine Peel Composite Solid Beverage And Its Protective Effect On Mice With Acute Alcoholic Liver Injury, Lei Chang, Zhu Lingfeng, Zhu Lijun, Ou Feilin, Mao Yingchao, Fu Fuhua

Food and Machinery

[Objective] A solid beverage with antialcoholic function was developed by the raw materials of tangerine peel, hawthorn and Pueraria lobata, which had the same origin as food and medicine, and explore its protective effect on mice with acute alcoholic liver injury. [Methods] The dry paste rate and total flavone content were used as the indexes，the extraction process was selected by orthogonal test. The single factor method was used to optimize the forming process with the indexes of sensory evaluation, shaping rate and solubility. A mouse model of acute alcoholic liver injury was established by administering 52% alcohol. The liver …

Effect Of Β-Hydroxy-Β-Methylbutyric Acid On Muscle Protection During Taekwondo Team Training, Song Boya, Jiang Tao, Gou Bo, Wang Qirong, Liu Qiang, Feng Haotian

Food and Machinery

[Objective] To investigate the effect of β-hydroxy-β-methylbutyrate （HMβ） supplementation on muscle protection in taekwondo players during training. [Methods] 18 male subjects above the second level of the Taekwondo special Team who voluntarily participated in the experiment were recruited and divided into experimental and control groups （9 each） according to the conditions. The experimental group consumed one sachet （25 g/bag, the amount of HMβ added was 500 mg/bag） of HMβ-added milk powder before and after training （with a break of more than 30 min） in the morning and afternoon from Monday to Saturday, …

Fermentation Technology And Effects Of Antioxidant And Anti-Exercise Fatigue Of Quinoa Haskap Complex Fermented Supernatant, Bai Haijun, Pang Weiqiao, Zhang Zhihui, Wang Ying

Food and Machinery

[Objective] This study aimed to optimize the fermentation process of quinoa-haskap complex fruit fermentation supernatant and develop anti-exercise fatigue food with high nutritional value. [Methods] Using black quinoa and haskap as raw materials, yeast combined with Lactobacillus for collaborative fermentation, the fermentation process conditions of composite fermentation juice were optimized by single factor and orthogonal test, and its anti-exercise fatigue effect on mice was deeply investigated based on animal experiments. [Results] The optimum fermentation conditions of quinoa-indigo fruit complex juice were as follows: initial pH 4.0, fermentation time 32 h, fermentation temperature 37 ℃, white sugar content 8%, and the …

Effects Of Ultrasonic Treatment Time On Meat Quality Of Yanbian Yellow Cattle, Sima Shengxue, Hao Beibei, Wu Zewen, Zhang Jiahui, Xia Guangjun

Food and Machinery

[Objective] This study aimed to improve the quality of Yanbian yellow beef during storage. [Methods] Yanbian yellow cattle eye meat and buttocks were used as experimental materials. Low frequency and high intensity (power 360 W, frequency 40 kHz) ultrasound technology was used to treat beef, and the effects of different ultrasound treatment time (0, 40, 60, 80 min) on the physical and chemical properties of beef during 10 days of storage were investigated. [Results] Extending ultrasonication treatment time significantly decreased the shear stress and redness value of beef (P＜0.05). Moreover, the analysis of myofibrils in beef after ultrasonic …

Research Progress On Health Care Function And Fruit Wine Of Aronia Melanocarpa, Tuo Longlong, Shi Pengbao, Chai Juhua, Shen Fei

Food and Machinery

Based on recent domestic and foreign research results, the health care function and fruit wine development of Aronia melanocarpa were reviewed. The types and technology research progress of the fruit wine were emphasized, and the challenges and opportunities of current development of the fruit wine were analyzed.

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.

Bacteroides Ovatus Alleviates Dysbiotic Microbiota-Induced Graft-Versus-Host Disease, Eiko Hayase, Tomo Hayase, Akash Mukherjee, Stuart C Stinson, Mohamed A Jamal, Miriam R Ortega, Christopher A Sanchez, Saira S Ahmed, Jennifer L Karmouch, Chia-Chi Chang, Ivonne I Flores, Lauren K Mcdaniel, Alexandria N Brown, Rawan K El-Himri, Valerie A Chapa, Lin Tan, Bao Q Tran, Yao Xiao, Christopher Fan, Dung Pham, Taylor M Halsey, Yimei Jin, Wen-Bin Tsai, Rishika Prasad, Israel K Glover, Altai Enkhbayar, Aqsa Mohammed, Maren Schmiester, Katherine Y King, Robert A Britton, Pavan Reddy, Matthew C Wong, Nadim J Ajami, Jennifer A Wargo, Samuel Shelburne, Pablo C Okhuysen, Chen Liu, Stephanie W Fowler, Margaret E Conner, Zoe Katsamakis, Natalie Smith, Marina Burgos Da Silva, Doris M Ponce, Jonathan U Peled, Marcel R M Van Den Brink, Christine B Peterson, Gabriela Rondon, Jeffrey J Molldrem, Richard E Champlin, Elizabeth J Shpall, Philip L Lorenzi, Rohtesh S Mehta, Eric C Martens, Amin M Alousi, Robert R Jenq

Faculty, Staff and Student Publications

Acute lower gastrointestinal GVHD (aLGI-GVHD) is a serious complication of allogeneic hematopoietic stem cell transplantation. Although the intestinal microbiota is associated with the incidence of aLGI-GVHD, how the intestinal microbiota impacts treatment responses in aLGI-GVHD has not been thoroughly studied. In a cohort of patients with aLGI-GVHD (n = 37), we found that non-response to standard therapy with corticosteroids was associated with prior treatment with carbapenem antibiotics and a disrupted fecal microbiome characterized by reduced abundances of Bacteroides ovatus. In a murine GVHD model aggravated by carbapenem antibiotics, introducing B. ovatus reduced GVHD severity and improved survival. These beneficial effects …

Pms 5 (End Matter), Poemmemoirstory Staff

PoemMemoirStory (literary magazine)

pp. 132-138

Lunch With Oprah, Cinthia Ritchie

PoemMemoirStory (literary magazine)

pp. 75-87

Definition Of Terms, Lucia Perillo

PoemMemoirStory (literary magazine)

pp. 53-57

Tail, Elizabeth Rollins

PoemMemoirStory (literary magazine)

pp. 117-125