Digital Commons Network^™

Pediatric Cardiac Xenotransplantation And Expanded Access: Ethical Considerations, Daniel J Hurst, Christopher Bobier, Anthony Merlocco, Luz A Padilla, Daniel Rodger, David Cleveland, John D Cleveland

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Due to the current organ shortage waitlist, alternatives to allotransplantation are necessary. Xenotransplantation is currently being pursued as one such alternative in adults in need of kidney or heart transplantation. Cardiac xenotransplantation of genetically modified pig hearts has been conducted twice in adults under the United States Food and Drug Administration (FDA) expanded access criteria. Because of the shortage of transplantable hearts for children as well as the lack of mechanical circulatory support in this population, pediatric researchers are exploring FDA expanded access in high-risk neonates and infants who lack alternative options for survival. The adult cardiac xenotransplantation experience with …

The Parthenon, October 16, 2024, Evan Green, Sarah Davis, Baylee Parsons, Kaitlyn Fleming, Scott Price, Abigail Cutlip, Rafael Alfonso, Wade Sullivan

The Parthenon

No abstract provided.

2024-10-16 Nordic Museum Unveils Unconventional Multimedia Exhibit, Milan Damjanac

The Spectator Online

No abstract provided.

Oregon State Rank Assessment For Warner Basin Tui Chub (Siphateles Bicolor Ssp. 15), Eleanor P. Gaines, Jesse Laney

Institute for Natural Resources Publications

Oregon state conservation status assessment for Warner Basin tui chub (Siphateles bicolor ssp. 15) using NatureServe methodology, 2024.

October 16, 2024 (Vol. 109, No. 8), Daily Eastern News

Daily Eastern News: 2024-2025

No abstract provided.

Contributions Of Speaking, Listening, And Semantic Depth To Word Learning In Typical 3- And 4-Year-Olds, Peter Richtsmeier, Allison Gladfelter, Michelle Moore

CISLL Publications

Purpose: This study examined learning via perception, learning via production, and semantic depth as contributors to word learning in preschool-aged children. There is broad evidence that semantic depth is an important contributor to word learning, especially when semantic cues are repeated and spaced out over time. Perceptual learning and production learning each support word learning sometimes, but not in all cases. The purpose of this study was to examine all three learning mechanisms within a single experimental paradigm.

Method: Thirty-six typically developing preschool children completed the experiment. They were familiarized with 16 novel words that were contextualized as alien names. …

Shan Song Xiao: English Edition, Xifu, Jane Li, Paul Royster

Zea E-Books Collection

This book describes the family story of three generations of daughters over the past century, starting from the grandmother to the mother, and then to the daughter. They lived overlapping lives, but each follows a different life path in different eras with different main themes. As time flies and life rushes by, they look back on the past and document their lives.

The story travels from a rural village in Northeast China to an overcrowded modernized metropolis. It unfolds against a backdrop of invasion and occupation, liberation, collectivization and famine, the Great Leap Forward, the Cultural Revolution, and the emergence …

Do Linear Clearings In Boreal Peatlands Recover? Comparing Taxonomic, Phylogenetic, And Functional Plant Diversity, Ellie M. Goud, Scott J. Davidson, Anna Dabros, Kimberly Kleinke, Megan A. Schmidt, Maria Strack

School of Geography, Earth and Environmental Sciences

Land-use changes and anthropogenic disturbances are major threats to biodiversity, affecting ecosystem function and recovery. In boreal Alberta, Canada, petroleum development has led to extensive landscape fragmentation, notably through linear clearings created for seismic exploration that remove surface vegetation and microtopography. Despite partial recovery on forested seismic lines, peatland recovery is often arrested, impacting wildlife and carbon dynamics. Restoration efforts employ silviculture techniques to create microtopography and foster tree growth, but the efficacy of restoration treatments in restoring peatland plant diversity remains uncertain. We compared taxonomic, phylogenetic, and functional diversity of understory plant communities across treated and untreated seismic lines, …

Characterization Of Non-Standard Viral Genomes During Arenavirus Infections Identifies Prominent S Rna Intergenic Region Deletions, Matthew Hackbart, Carolina B López

2020-Current year OA Pubs

Arenaviruses, a family of negative-sense RNA viruses spread by rodents, are a leading cause of severe hemorrhagic fever in humans. Due to a paucity of antivirals and vaccines for arenaviruses, there is a need to identify new mechanisms for interfering with arenavirus replication. In several negative-sense RNA viruses, natural viral interference results from the production of non-standard viral genomes (nsVGs) that activate the innate immune system and/or compete for essential viral products. Although it is well established that arenaviruses produce strong interfering activities, it is unknown if they produce interfering nsVGs. Here, we show that arenaviruses produce deletions within the …

Three-Dimensional Outdoor Object Detection In Quadrupedal Robots For Surveillance Navigations, Muhammad Hassan Tanveer, Zainab Fatima, Hira Mariam, Tanazzah Rehman, Razvan Cristian Voicu

Faculty Articles

Quadrupedal robots are confronted with the intricate challenge of navigating dynamic environments fraught with diverse and unpredictable scenarios. Effectively identifying and responding to obstacles is paramount for ensuring safe and reliable navigation. This paper introduces a pioneering method for 3D object detection, termed viewpoint feature histograms, which leverages the established paradigm of 2D detection in projection. By translating 2D bounding boxes into 3D object proposals, this approach not only enables the reuse of existing 2D detectors but also significantly increases the performance with less computation required, allowing for real-time detection. Our method is versatile, targeting both bird’s eye view objects …

The Need For Accurate [And Respectful] Depictions Of Mental Illness In Fiction, Jacequlyn L. Mills

Masters Theses

This thesis seeks to address the ongoing misrepresentation of mental illness in popular media, specifically within film, television, and literature. The power of the media is instrumental in public perception, and the ongoing negative misinformation and inaccuracy of mental illness those who are affected by it in media is instrumental in spreading harmful stereotypes and stigma. This affects not only the way that the general public views mental illness but also the way those with mental illness view themselves as well as their desire to seek help. I use these forms of media to showcase both the negative and positive …

Alpha-Glycerylphosphorylcholine (A-Gpc) Supplementation And Perceived Health Status, Michael Roman Iv

Doctoral Dissertations and Projects

The aim of this dissertation is to determine if there is a correlation between A-GPC supplementation and perceived health via a quantitative correlational design. The content of this manuscript demonstrates that A-GPC can increase motivation in human subjects as well as improve mood and reduce subjective feelings of sadness. Moreover, A-GPC presents the ability to influence the primary means of rapid communication throughout the human body via its ability to influence dopaminergic, serotonergic, and GABAergic neurotransmission, which play essential roles in the regulation of arousal, reward, pleasure, and motivation. The purpose of this study is to assess the perceived health …

When Obedience Becomes A Sacrifice: Creating And Sustaining Resilient Leaders, Janet G. Wooten

Doctoral Dissertations and Projects

This thesis, “When Obedience Becomes a Sacrifice,” discusses the role of sacrifice in obeying God's call to lead. The lay leaders of Call to Conquer Ministries do not seem to understand this role, leading to ministry challenges. This research aims to provide a deeper understanding of the role of sacrifice in leadership and how to maintain resiliency during difficult times. Potential leaders answer God’s call to lead, believing that “obedience is better than sacrifice" (1 Samuel 15:22a). However, there is a lack of full clarity concerning the sacrifices made because of their obedience. The question to be addressed is “What …

Developing A Biblical Worldview: Equipping African American Leaders With The Tools Needed To Combat The Reemergence Of Syncretism Within The African American Church, William Taft Wallace Jr.

Doctoral Dissertations and Projects

Historically, African Americans have grappled with questions of identity, a struggle initially precipitated by the diaspora. Over time, this ongoing struggle has led many to seek answers from various sources, each of which has influenced and shaped their worldview. In response to this ongoing identity crisis, the African American church has traditionally served as a stabilizing force, emphasizing that identity is rooted in the image of God, as affirmed by the Bible. However, today’s African American church faces significant insider threats from other African American-based groups that promote counter-biblical and anti-Christian narratives regarding identity. These threats have infiltrated the church, …

The Voices Of Black Women: Experiences Of Intimate Partner Violence And Mandatory Arrest, Lacoya Charnis Crape

Doctoral Dissertations and Projects

The purpose of this phenomenological study was to understand the lived experiences of Black female victims of IPV concerning mandatory arrest and how they perceive the outcomes and effects of the arrest on either partner involved. The findings revealed that Black women had mixed experiences with mandatory arrest; those with Black abusers reported positive experiences with this law, and those with White abusers experienced negative encounters. Eight out of twenty-three mandatory arrest states were identified as problematic states by Black women due to measures of poor police performance. Outcomes suggest that Black women with White abusers experience unique barriers associated …

Stories Of The Re-Awakening, Joseph Cecil Broadbent

Masters Theses

The Present piece takes a look at the realms of the fantastical and vital elements that help to create a best seller. The creative piece is a brief look into a hopefully soon to be published Fantasy/Science Fiction Young Adult Teenage series. Brief insights are followed by a prologue and four book beginnings to welcome the reader into its world.

An Ethnically Balanced Male Perspective Towards Police Officers Seeking Mental Health Counseling: A Hermeneutic Phenomenological Study, Arturo Parra

Doctoral Dissertations and Projects

This phenomenological study will aim to understand an ethnically balanced male perspective toward police officers seeking mental health counseling. Police Officers are routinely exposed to stressful and traumatic events, leading to acute and chronic disorders, mental illnesses, suicide ideation, and suicide, as research has indicated. Mental health counseling can play an essential role in intervention into mental health illness, providing critical tools to police officers to handle stress and potential mental illness. However, reluctance among the police community to seek mental health counseling continues to be prevalent. Possible cause for this reluctance are suggested through research as a direct result …

Vitamin D Deficiency As A Sign Of Severity In Bronchiectasis, Mustafa Eskander Salman, Mohammed Waheeb Al-Obaidy

Muthanna Medical Journal

Bronchiectasis is a chronic heterogeneous lung disease with poorly understood pathogenic processes and variable contributing factors. The aim of this study is to assess the prevalence and the impact of vitamin D deficiency in bronchiectasis patients. A cross-sectional study of 40 Baghdad teaching hospital respiratory diseases consultant outpatient clinic patients with verified bronchiectasis was undertaken between 2022 and 2023. 40 healthy, demographically matched controls were also studied. A detailed history, comprehensive physical examination with respiratory emphasis, and vitamin D level evaluation were done. Vitamin D levels were categorized as deficient (< 20 ng/ml), insufficiency (20–29.9 ng/ml), and adequate (≥ 30 ng/ml). Patients were categorized as frequent exacerbates (≥3 times/year) or non-frequent exacerbates (<3 times/year). Symptom intensity was further divided into mild, moderate, and severe. We studied 40 bronchiectasis patients, 21 of them were male and 7 had comorbidities. The mean age, BMI, ESR, and CRP for included patients were 39 years, 23.945 kg/m2, 9.65 ml/hr, and 0.234 mg/dL. Group vitamin levels averaged 19.68 ng/ml. Average annual exacerbation, BSI, Bhalla, and FEV1 scores were 1.95, 6.325, 14.275, and 85.8%. Bronchiectasis patients and healthy controls had similar demographic and clinical features except for vitamin D and CRP. Exacerbation number, BSI score, Bhalla score, and FEV1 correlated with vitamin D but not ESR or CRP. In conclusion, Vitamin D insufficiency is common in bronchiectasis patients and healthy people and is linked to poor symptom severity, radiological abnormalities, and lung function.

Juror Number Six: Implicit Bias And The Future Of Jury Trials, Dave Mcgowan

San Diego Law Review

Implicit bias concepts have been quick to take hold in the law. Their influence may be traced through mandatory continuing education requirements, statutory restrictions on jury selection, jury instructions, and, in two recent rulings from the Washington Supreme Court, judicial limits on juror deliberations and permissible arguments. These limits use implicit bias premises to experiment with altering the balance of interests served by jury trials.

Part II of this Article tells the story of the trial of Tomas Berhe, who was convicted of shooting Everett Williams to death. Mr. Berhe’s case led to an extraordinary event: a live hearing in …

A Combination Of Four Toxoplasma Gondii Nuclear-Targeted Effectors Protects Against Interferon Gamma-Driven Human Host Cell Death, Brittany Henry, Aubrey J Phillips, L David Sibley, Alex Rosenberg

2020-Current year OA Pubs

In both mice and humans, Type II interferon gamma (IFNγ) is crucial for the regulation of

Critical Reflections On Salamander. A Response To “Land Education And Young People Working Toward Salamander”, Jay Odenbaugh, Stacy Meyer

Democracy & Education

In this response, we examine what it means to center Indigenous perspectives, how we can avoid overly individualistic approaches to examine the well-being of students, and how SALAMANDER might be implemented with younger students.

Democratic Practices As Part Of Mathematical Modeling In Schools, Lisa Steffensen, Inger Elin Lilland, Shengtian Zhou

Democracy & Education

We focus on how democratic practices occur during the modeling activity “The Candy Bag of Dreams.” With democratic practices, we refer to approaches supporting inclusivity and active participation aimed at empowering students. We investigated one group of preservice teachers implementing an optimizing modeling activity during practicum in two fifth-grade classes, where students modeled their dream candy bags. Students engaged in mathematical modeling where mathematics was embedded in their social context, and they negotiated meanings and developed perspectives. Through this, they experienced lived democracy by actively engaging in and through democratic practices.

We found democratic practices such as students inviting peers …

A Long-Recognized But Undescribed New Species Of Cyprinella (Cypriniformes: Leuciscidae) From North Carolina And South Carolina, United States, Bryn H. Tracy, Fred C. Rohde, Michael A. Perkins, Laura M. Lee, Kara B. Carlson, Madelyn Mccutcheon, Brena K. Jones, Heather K. Evans

Southeastern Fishes Council Proceedings

Cyprinella leptocheilus sp. nov., Siouan Thinlip Chub, is described as a new species that is endemic to Sand Hills and upper Coastal Plain streams in North Carolina and South Carolina. Recognized as an undescribed species since the early 1970s, this fish was known in the literature and in museum electronic databases as Hybopsis n. sp., H. sp. cf. zanema, Cyprinella n. sp., and C. sp. cf. zanema. Unofficially, it had gone by the common name Thinlip Chub. It was thought to be closely related to the two other barbeled Cyprinella species: Thicklip Chub, …

The Horrific Anxiety Of Resurrection: A Study Of Uncanny Mirroring In The Gothic, J.R. J. Rizzo

Locus: The Seton Hall Journal of Undergraduate Research

The overall theme of this paper surrounds the anxiety when coming face-to-face with the uncanny. More broadly, it seeks to unite the field of psychoanalysis and the horror genre in a symbiotic relationship. It is my belief, that within the heart of horror lies the mycelium of the uncanny. That is, where horrific themes and devices are, so too lives the uncanny.

Preventing Musculoskeletal Disorders In Navajo Weavers, Ramona F. Yazzie, Kimberly Masker, Kristin Biggins

The Open Journal of Occupational Therapy

The Navajo Nation is one of the many reservations that lack access to health care services, leading to increasing chronic health conditions. Navajo rug weaving is a common creative occupation on the reservation. Navajo rug weaving involves multiple steps in creating a beautiful rug. The multiple steps include repetitive gripping, pinching, reaching, pulling, and prolonged sitting. Therefore, weavers are at risk for developing musculoskeletal disorders (MSDs), preventing individuals from participating in meaningful occupations. Occupational therapists have the skills to provide appropriate education through active listening, visual handouts, and family members. However, occupational therapists must demonstrate and understand cultural sensitivity to …

A Feline Gastrointestinal Eosinophilic Sclerosing Fibroplasia In A Scottish Fold Cat: A Case Report, Rattanin Chiewcharnvalijkit, Weerapat Chawanlawuthi, Kittara Chanmongkolpanit, Tanit Kasantikul, Nlin Arya, Sirintra Sirivisoot, Sirima Chatrungruengkul, Duangtip Chatchaisak

The Thai Journal of Veterinary Medicine

A 2-year-old intact female Scottish fold cat was presented to the Prasu-Arthorn Animal Hospital, Faculty of Veterinary Science, Mahidol University, for a right nephrectomy because a renal mass was suspected. During the physical examination, the animal had an intra-abdominal mass with abdominal discomfort. No history of vomiting and diarrhea was reported. The blood chemistry and hematology revealed a markedly low albumin/globulin ratio and mild anemia with normal leukogram. The abdominal ultrasonographic examination and CT scan revealed an intestinal mass at the ileocecocolic junction. The mass was surgically excised, and jejuno-colic anastomosis was performed. Grossly, the mass was firm, very well …

Outdoor Educational Opportunities And Movement Breaks Effect On Mental, Social, Emotional Health Of Adolescents, Nathaniel Ballard

Graduate Teacher Education

This paper examined research intent on the purpose of studying how educational leaders may support the mental, social, and emotional health of adolescents through incorporating outdoor educational opportunities and movement breaks in the classroom. The qualitative, quantitative, and mixed method approaches used, delve into the ways of incorporating movement in the classroom through brain breaks, utilizing outdoor education opportunities, and the effects technology can have. These concepts and tools can work together to support the mental, social, and emotional health of adolescents as well as to promote greater academic growth. However, they must be utilized appropriately for intended success. The …

Monocyte And Macrophage Functions In Oncogenic Viral Infections, Juliana Echevarria-Lima, Ramona Moles

Cell and Molecular Biology Publications

Monocytes and macrophages are part of innate immunity and constitute the first line of defense against pathogens. Bone marrow-derived monocytes circulate in the bloodstream for one to three days and then typically migrate into tissues, where they differentiate into macrophages. Circulatory monocytes represent 5% of the nucleated cells in normal adult blood. Following differentiation, macrophages are distributed into various tissues and organs to take residence and maintain body homeostasis. Emerging evidence has highlighted the critical role of monocytes/macrophages in oncogenic viral infections, mainly their crucial functions in viral persistence and disease progression. These findings open opportunities to target innate immunity …

An Emerging Multi-Omic Understanding Of The Genetics Of Opioid Addiction., Eric O Johnson, Heidi S Fisher, Kyle A Sullivan, Olivia Corradin, Sandra Sanchez-Roige, Nathan C Gaddis, Yasmine N Sami, Alice Townsend, Erica Teixeira Prates, Mirko Pavicic, Peter Kruse, Elissa J Chesler, Abraham A Palmer, Vanessa Troiani, Jason A. Bubier, Daniel A Jacobson, Brion S Maher

Faculty Research 2024

Opioid misuse, addiction, and associated overdose deaths remain global public health crises. Despite the tremendous need for pharmacological treatments, current options are limited in number, use, and effectiveness. Fundamental leaps forward in our understanding of the biology driving opioid addiction are needed to guide development of more effective medication-assisted therapies. This Review focuses on the omics-identified biological features associated with opioid addiction. Recent GWAS have begun to identify robust genetic associations, including variants in OPRM1, FURIN, and the gene cluster SCAI/PPP6C/RABEPK. An increasing number of omics studies of postmortem human brain tissue examining biological features (e.g., histone modification and gene …

Advancing Stem Cell Technologies For Conservation Of Wildlife Biodiversity., Ashlee M Hutchinson, Ruth Appeltant, Tom Burdon, Qiuye Bao, Rhishikesh Bargaje, Andrea Bodnar, Stuart Chambers, Pierre Comizzoli, Laura Cook, Yoshinori Endo, Bob Harman, Katsuhiko Hayashi, Thomas Hildebrandt, Marisa L Korody, Uma Lakshmipathy, Jeanne F Loring, Clara Munger, Alex H M Ng, Ben Novak, Manabu Onuma, Sara Ord, Monique Paris, Andrew J Pask, Francisco Pelegri, Martin Pera, Ryan Phelan, Benyamin Rosental, Oliver A Ryder, Woranop Sukparangsi, Gareth Sullivan, Nicole Liling Tay, Nikki Traylor-Knowles, Shawn Walker, Antonia Weberling, Deanne J Whitworth, Suzannah A Williams, Jessye Wojtusik, Jun Wu, Qi-Long Ying, Thomas P Zwaka, Timo N Kohler

Faculty Research 2024

Wildlife biodiversity is essential for healthy, resilient and sustainable ecosystems. For biologists, this diversity also represents a treasure trove of genetic, molecular and developmental mechanisms that deepen our understanding of the origins and rules of life. However, the rapid decline in biodiversity reported recently foreshadows a potentially catastrophic collapse of many important ecosystems and the associated irreversible loss of many forms of life on our planet. Immediate action by conservationists of all stripes is required to avert this disaster. In this Spotlight, we draw together insights and proposals discussed at a recent workshop hosted by Revive & Restore, which gathered …