Anti-Inflammatory Potential Of Black Cumin Seed Oil And Its Nanoemulsion Formulation Against Lipopolysaccharide-Induced Liver Injury In Mice, Shady Swidan, Hesham Hafez, Rehab Hosni, Hatem Amin

Pharmacy

Original Article

Anti-inflammatory potential of black cumin seed oil and its nanoemulsion formulation against lipopolysaccharide-induced liver injury in mice

Haffez, Hesham^1,2,✉; Hosni, Rehab³; Swidan, Shady A.⁴; Amin, Hatem K.^1,5

Author Information

¹Biochemistry and Molecular Biology Department, Faculty of Pharmacy, Helwan University, Helwan, 11795, Cairo, Egypt

²Center of Scientific Excellence “Helwan Structural Biology Research”, Helwan University, Helwan, 11795, Cairo, Egypt

³El Sisi Comprehensive Clinic, General Authority for Health Insurance-Giza, Haram, 12556, Giza, Egypt

⁴Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, The British University in Egypt, El-Sherouk, 11837, Cairo, …

Gandy Dancer 13.1 (Fall 2024), Gandy Dancer

Gandy Dancer Archives

Gandy Dancer is a literary magazine, publishing fiction, poetry, creative nonfiction, and visual art. We invite submissions from student writers and artists at all of the SUNY campuses. Edited by students at SUNY Geneseo, Gandy Dancer is published twice yearly. For more information, visit www.gandydancer.org. Gandy Dancer 13.1 is the twenty-fourth issue, published Fall 2024.

Breast Cancer: Her2-Mutant P53 Cooperation And The Cell-Of-Origin Dependent Dynamics, Abie Williams-Villalobo

Dissertations (2016-Present)

Subtype. Specifically, NCP172 and NCP245 tumors grew faster and were predominantly triple- negative than NCP245. RNA sequencing identified many differentially expressed genes (DEGs) between tumor and mammary gland controls. Ingenuity Pathway Analysis (IPA) of the DEGs revealed that pathways like Deubiquitination, Cell Cycle Checkpoints, RHO GTPase cycle, and HIF1α Signaling were associated with aggressive tumor characteristics, with heightened pathway activity in NCP172 likely contributing to greater growth and invasiveness.

This study further examined how different cells-of-origin contribute to breast cancer heterogeneity by inducing mutant p53 in either mammary myoepithelial or luminal cells. Tumors originating from myoepithelial cells (Tk5) exhibited …

Vavanga, Vavalo, And Fakakaukau With Vā-Tā, Siosiua F.P. Lafitani

Pacific Studies

This article addresses the profound cognitive and cultural significance of vavanga (contemplation) and vavalo (contemplation), which are contempla- tive frameworks deeply rooted in the concept of vā (space) within Tongan language and culture. These frameworks serve as gateways to expansive cogni- tive exploration, stretching the boundaries of imagination and contemplation. Fakakaukau (thinking), double or dual actor (named because it bridges the realms of cognition and practicality), uses instrumental concepts such as fifili (inquisitiveness) and fekeli (meticulous exploration) to navigate the landscapes of inquiry. Throughout this exploration, a critical distinction emerges between tā as tempo and the cognitive concepts of contemplation …

Beauty Beyond Barbed Wire: Chiura Obata’S Perspective Of The Horizon, Bri Carlson

Theses

Depictions of the environment are an integral part of American art history because they convey cultural relationships of all who inhabited the land. The environment is often a stagnant force that harbors lifetimes of human history. One of these histories is the incarceration of about 120,000 Japanese immigrants and American citizens in 1942 after the bombing of Pearl Harbor. They were forced to evacuate their homes, lives, and families to live in detention centers and prison camps where living conditions were subpar. Many turned to art making to cope, and some artists used their work to silently protest and visually …

Contents, Journal Editors

Journal of Food Law & Policy

No abstract provided.

Detection Of Apiary Sites From Remote Imagery, Ning Li

Theses and Dissertations

Honey bees are essential for honey production and pollination services, but their colonies have been declining despite increasing demand. This decline may be due to various factors, including habitat loss, altered land use, climate shifts, and pesticide exposure. In order to assess the quantity and quality of habitats for honey bees and determine their availability and suitability for supporting bee colonies, it is crucial to identify the spatial location of registered apiary sites being used. However, such data is not available, which makes it a challenge for researchers in the field to further advance honey bee-related investigations. In my study, …

Measuring Palatability Of Pet Food Products: Sensory Components, Evaluations, Challenges, And Opportunities, Natalia Calderon, Brittany L. White, Han-Seok Seo

Food Science Faculty Publications and Presentations

The pet food industry is a growing business launching a variety of new products in the market. The acceptability or preference of pet food samples has traditionally been measured using either one-bowl or two-bowl tests. Academic researchers and professionals in the pet food industry have explored other methods, including the cognitive palatability assessment protocols and the ranking test, to evaluate more than two samples. A variety of approaches and perspectives were also utilized to predict palatability and key sensory attributes of pet foods, including descriptive sensory analysis by human-trained panelists and pet food caregivers’ perceptions of pet food. This review …

Predicting Different Psychological Profiles Amongst Substance Users., Zach J. Gray

Graduate Theses and Dissertations

Substance use disorders (SUDs) are some of the most prevalent issues facing society. As SUDs are highly individualized in how they manifest, recent work has attempted to classify distinct profiles of drug users to better understand what factors put someone at risk for shifting from casual substance use to developing a substance use disorder (SUD). Common risk factors for SUD development include stressor exposure, difficulties with emotion regulation, personality, and risky decision-making. As many of the behaviors that constitute SUDs are exhibited prior to potential diagnosis, developing “profiles” that combine these traits and experiences could eventually predict SUDs. The current …

Assessing The Short-Term Outcomes Of Erase And Replace: A Series Of Health & Wellness Activities, Gabriela Murza, Christina Pay, Eva Timothy, Melanie Dabb, Cris Meier

Outcomes and Impact Quarterly

Utah State University Extension faculty addressed Utah's high rate of poor mental health with activities that improved participants’ connections, confidence, and abilities. These efforts positively impacted adults' mental health and quality of life and offered an additional resource to address self-care needs while encouraging connection and skill-building.

Leadership Ways Of The Three Fires Anishinaabek, Grace Boda

Dissertations

Leadership has often been viewed through a narrow lens that primarily reflects Western perspectives, while Indigenous knowledge has been overlooked, marginalized, or excluded, perpetuating colonial systems. This study aims to restore Indigenous knowledge within the Three Fires Anishinaabek community and to contribute to a more comprehensive understanding of leadership. Employing an Indigenous research methodology, the study centers relational and wholistic ways of knowing. This approach adheres to Indigenous ethics of relational accountability and utilizes a collaborative strategy for knowledge gathering (data collection) through conversational interviews.

As knowledge contributors (participants), members of the Three Fires Anishinaabek community engaged in discussions that …

Enhancing Assessment And Feedback In Game Design Programs: Leveraging Generative Ai For Efficient And Meaningful Evaluation, James Hutson, Ben Fulcher, Jay Ratican

Faculty Scholarship

The integration of generative AI tools in game design education offers promising ways to streamline the grading, assessment, and feedback processes that are typically labor-intensive. In game design programs, faculty often deal with varied file formats, including 3D models, executable prototypes, videos, and complex game design documents. Traditional methods of assessment and feedback, primarily text-based, struggle to provide timely and actionable insights for students. Furthermore, only a small percentage of top students consistently review and apply feedback, leading to inefficiencies. This article explores how generative AI tools can augment these processes by automating aspects of grading, generating more personalized and …

Psychological Impacts Of Competitive Dance: Understanding Mental Health And Team Dynamics Among Young Dancers, Gloria E. Brunner

Master's Theses

The purpose of the research was to investigate deeply into the psychological aspects of competitive dance and its influence on the mental well-being of young dancers. Competitive dance has grown significantly in popularity, fueled by reality television shows and social media platforms, creating a high-pressure environment for participants. This research investigated the unique stressors faced by young dancers including performance anxiety, body image concerns, and burnout, while also identifying coping strategies and the positive personal development fostered through dance.

To uncover more information about the positive and negative effects of competition dance, the researcher focused the study on the following …

They Can't Know I Wanna Kiss Robots: Stigma And Audience Segregation In Fanfiction, Micah Arrow Callin

Master's Theses

Fanfiction writers have long faced public stigma, which emerged with the rise of fandom and, according to recent claims, may be lessening as fandom identities gain wider acceptance. However, the practice of fanfiction writers intentionally segregating their audiences remains a deeply embedded aspect of fandom culture, with limited understanding of its underlying motivations. The purpose of this study was to analyze the audience segregation employed by online fanfiction authors in order to understand why they choose to segregate their audiences, and specifically to determine the influence of social stigma on these choices, answering these main questions: Is there segregation between …

Exploring The Impact Of Dance Arts Integration On General Education Teaching Practices: Insights Into Classroom Environment, Planning, Instruction, And Assessment, Sara Kessler-Kennon

Master's Theses

The purpose of this research study was to explore the impact of dance arts integration facilitation on teaching practices by emphasizing classroom environment, planning, instruction, and assessment. The researcher created the following four essential questions to guide the study:

Q1 How does incorporating movement-based arts integration alter classroom environment, student behavior, student engagement, and inclusivity of students with various abilities and diverse backgrounds?

Q2 How does incorporating movement-based arts integration impact the general educators' planning time, process, style, and understanding? Does the general educator feel as though they can effectively incorporate movement-based arts integration without collaborating with a dance educator? …

North Sinai Bedouin Veil From The May Weber Ethnographic Study Collection, Jupiter Beck

Department of Anthropology

This report is on a North Sinai Bedouin Veil/Burqa from the May Weber Ethnographic Study Collection. It details the materials, the methods of construction, the attribution, and the cultural significance of the veil/burqa.

Becoming A Poor Church For The Poor: The Vincentian Charism, An Invitation To The Church’S Bold Reform Today, Dominique Iyolo

Vincentian Studies

Dominique Iyolo explains how the Vincentian charism anticipated and is reflected in Pope Francis’s Evangelii Gaudium, and how it is being put into practice for the service of the poor in the Democratic Republic of the Congo and Madagascar. Iyolo discusses the theology behind the preferential option for the poor and also describes how their suffering is caused by a spiritual poverty of the rest of the world.

Ways Of Knowing: Laywomen In Early Vincentian Practices Of Reform, Alison Forrestal

Vincentian Studies

Alison Forrestal examines the role of laywomen of various social classes in early Vincentian service. Although the concept of a lay vocation had not been formulated in the seventeenth century, the service that laywomen, whether married or single, provided to society rendered their state valuable and holy in its own right. This was an important facet of the Catholic Reformation. Early Vincentian efforts were innovative for the time, allowing women to organize and perform the administrative work for their own service. Women also gave religious instruction to the poor, which was unusual, and their own spirituality and devotional activities were …

Disney's Postfeminist Follies: Disney’S Postfeminist Portrayal Of Women In The Age Of Fourth Wave Of Feminism, Morgan Crafton

Honors Theses

In 2022, Disney CEO Bob Chepak spoke out against the "Don't Say Gay" bill signed by Florida Governor Ron DeSantis. DeSantis’ supporters derisively labeled Disney as “woke." However, the company does not warrant the label. Though Fourth Wave feminism has broadened Disney’s idea of a woman, the entertainment company largely operates with a postfeminist lens that prevents its heroines from being feminist representations of women. Audiences see this in "Frozen," (2013), "Moana" (2016), "Encanto" (2021), and "Turning Red" (2022). Disney’s postfeminist rhetoric allows it to portray supposedly progressive women without challenging societal notions of misogyny. Thus, Disney’s criticisms for “wokeness” …

Teaching Learning Newsletter Vol 4 Issue 2, Sastra Deemed To Be University

TLC Newsletter

No abstract provided.

U-Glide Program Fall 2024, Unf Office Of Undergraduate Research, Unf Graduate School

Undergraduate – Graduate Learning, Inquiry, and Distinctive Experimentation (U-GLIDE) Symposium Programs

No abstract provided.

Microplastic Degradation Compared Among Dated Salton Sea Strandlines, Maria Alejandra Roman Medrano

Loma Linda University Electronic Theses, Dissertations & Projects

This thesis investigates the environmental degradation of plastic materials, with a focus on polyethylene terephthalate (PET), through a multi-phase study conducted at the Salton Sea, a closed-basin lake in a semi-arid region of California. The research addresses three core objectives: (1) developing a microplastic (MP) extraction method tailored for clay-rich sediments, (2) characterizing surface degradation of various plastic types, including PET, BoPET, HDPE, LDPE, and EPS, using advanced microscopy and spectroscopy, and (3) examining the long-term weathering of PET through samples collected from dated lake strandlines.

The extraction protocol successfully isolates MPs without oxidation, using ZnCl₂ and extended soaking to …

Identification Of Lncrnas Involved In The Host Response To Venezuelan Equine Encephalitis Virus Infection, Mahgol Behnia

Biomedical Sciences ETDs

Venezuelan equine encephalitis virus (VEEV) is an enveloped positive-sense RNA virus in the alphavirus genus of the Togaviridea family, that causes encephalitis in humans and equids. Currently no FDA-approved vaccine or treatment is available for human use, emphasizing the importance of studying host-VEEV interaction. lncRNAs are regulatory RNAs involved in modulation of antiviral pathways during viral infections. Here we report differential lncRNAs expression in primary mouse astrocytes and neurons during non-pathogenic (TC-83) but not pathogenic (TrD) VEEV infection. We further demonstrated that suppression of four lncRNAs increased TC-83 replication, with lncRNA small nucleolar RNA host gene 15 (Snhg15) increasing TC-83 …

The Role Of Wt1 In Müllerian Duct Development, Jace Aloway

Dissertations and Theses (Open Access)

WT1 is a zinc finger transcription factor widely expressed in the urogenital system. Human mutations of WT1 lead to pediatric nephroblastoma as well as frequent differences of sex development (DSDs). Previous studies have suggested that WT1 acts as an activator for Amhr2, a necessary component of typical male differentiation. We used the mouse as a model to investigate the role of WT1 in sex development, where we deleted Wt1 in the Müllerian duct (MD) mesenchyme using a novel conditional null reporter allele, Wt1 flox-RFP. This allele utilizes the Cre-lox system to delete exons 8 and 9 of Wt1 …

The Magic Of Bioluminescence: How Animals Illuminate The Dark, Eleanor St. Clair

The Synapse: Intercollegiate science magazine

No abstract provided.

To Mine Or Not To Mine?: Discovery Of Polymetallic Nodules And Discussions On Deep-Sea Mining, Haze Doleys

The Synapse: Intercollegiate science magazine

No abstract provided.

Effects Of Culture Media And Duration On In Vitro Maturation And Production Of Cỏ Goat Embryos, Van Khanh Nguyen, Huong Thi Thu Vu, Au Thi Hoang, Yen Thi Kim Pham, Dat Van Le, Lan Anh Thi Nguyen, Huu Xuan Quan, Lan Doan Pham

The Philippine Agricultural Scientist

This study aimed to evaluate the effects of maturation media and duration on the in vitro maturation (IVM) of Cỏ goat oocytes for the in vitro production of Cỏ goat embryos. In Experiment 1, the highest percentage of matured oocytes and blastocyst rates were observed in the IVM medium consisting of tissue culture medium (TCM) 199 + 10% fetal calf serum (FCS) + 50 ng/mL follicle stimulating hormone (FSH) + 100 μM cysteamine + 10 ng/mL epidermal growth factor (EGF) + 100 units/mL penicillin G potassium + 0.1 mg/mL streptomycin sulphate (P < 0.05). In Experiment 2, Cỏ goat oocytes were cultured in the same IVM medium for 20, 22, and 24 h, respectively. The matured oocyte and blastocyst rates of the 20-h group were lower than those of the 22- and 24-h groups (61.56% vs. 76.81% and 73.48%; 13.76% vs. 24.75% and 24.72% respectively; P < 0.05), while there was no difference between the 22- and 24-h groups (P > 0.05). In conclusion, the TCM 199 medium supplemented …

Hildegard Of Bingen’S Embryology: Enabling Women’S Reproductive Power Without Seed, Minji Lee

Department of Religion Faculty Scholarship and Creative Works

This paper examines Hildegard of Bingen’s embryological theory within the intricate landscape of medieval medicine and religion. It situates Hildegard’s understanding of conception within ongoing historical debates surrounding the roles of male and female reproductive substances, particularly the concept of seed or semen. By analyzing her conceptual framework against prevailing classical and medieval reproductive theories, the research illuminates Hildegard’s distinctive contribution to understanding conception as a holistic bodily process. Classical embryological discourse predominantly oscillated between Aristotle’s one-seed theory—which positioned men as sole generative agents—and Galen’s two-seed theory, which marginally acknowledged female reproductive participation. While technically aligning with Aristotelian principles by …

Toward An Urban Food Commons: Participatory Action Research On Food Apartheid And Community-Based Agrifood System Governance In Louisville, Ky., Mary Abigail Rudolph

Electronic Theses and Dissertations

This dissertation investigates the structural inequities fueling food apartheid in Louisville, Kentucky’s agrifood system and explores community-based governance as a path toward food justice. Through a participatory action research (PAR) framework, this study combines participatory geographic information systems (PGIS), focus groups, and autoethnography to engage directly with affected community members and collaborate with the Food in Neighborhoods (FIN) coalition. By prioritizing the voices of those most impacted by food insecurity, this research offers contributions to the fields of food justice, participatory governance, and urban food commons. The study situates Louisville’s food access issues within the broader neoliberal global agrifood system, …

Assessment Of Nephroprotective Properties Of Vitex Agnus Castus Extract In Cisplatin-Treated Wistar Rats: A Pilot Study, Aparna Tripathy, Babi Dutta, Archana Parampalli Raghavendra, Sudarshan Surendran

Open Access archive

Cisplatin (CP) is used to treat various solid tumors but is associated with nephrotoxicity, which varies with dose and duration. Vitex Agnus castus (VAC) berries, known for their anti-inflammatory and antioxidant properties, may alleviate CP-induced renal toxicity. To investigate the gender-specific responses to cisplatin-induced nephrotoxicity and evaluate VAC extract's nephroprotective effects. Four-month-old Wistar rats (n=36) (24 male, 12 female) were used. In phase 1, gender-based differences in CP-induced nephrotoxicity were assessed. The gender group with higher nephrotoxicity was selected for phase 2 to evaluate VAC's nephroprotective properties. Animals were randomly grouped as Normal Control (6 males & 6 females), CP …