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Gene Expression Regulation By Au-Rich Elements And Au-Rich Element Binding Proteins, Courtney Fay Jungers Dec 2024

Gene Expression Regulation By Au-Rich Elements And Au-Rich Element Binding Proteins, Courtney Fay Jungers

Arts & Sciences Graduate Student Theses and Dissertations

The regulation of messenger RNA (mRNA) splicing, stability, and translation efficiency are major modes for controlling gene expression – which is essential for life. RNA-binding proteins (RBPs) and microRNAs (miRNAs) are trans-acting factors that bind to cis-elements influencing the stability and translation of the mRNA transcript. AU-rich elements (AREs) are cis-elements that are targeted by AU-rich element binding proteins (ARE-BPs). Here, I show a novel role for AREs and AU-rich element binding protein 1 (AUF1) during alternative splicing and report on interactions of RBPs and miRNAs to design a new treatment for breast cancer by interrupting these interactions in the …

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A Filter-Based Model Of Visual Recognition, Olivia Rose Bockler Dec 2024

A Filter-Based Model Of Visual Recognition, Olivia Rose Bockler

Arts & Sciences Graduate Student Theses and Dissertations

Visual recognition, a key perceptual process, enables primates to identify faces, food, tools, and potential threats in their environment. Cortical neurons along the ventral visual stream—spanning from early visual cortex (V1) through inferotemporal cortex (IT), with long-range projections to ventrolateral prefrontal cortex (vlPFC)—are essential for visual recognition. Traditional models propose that neuronal representations increase in complexity in each stage of this pathway, culminating in object-specific representations in higher-order cortex. However, this hypothesis remains debated, particularly as artificial visual models have countered that individual neurons along this pathway may function more as filters contributing to distributed representations of objects. Thus, this …

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Aging, Fast And Slow: Gene Expression Signatures Of Physiological Age Vs. Future Lifespan In Caenorhabditis Elegans, Matthew Mosley Dec 2024

Aging, Fast And Slow: Gene Expression Signatures Of Physiological Age Vs. Future Lifespan In Caenorhabditis Elegans, Matthew Mosley

Arts & Sciences Graduate Student Theses and Dissertations

An outstanding question in the field of aging biology is the origin of variability in lifespans among members of the same species. Traditional wisdom dictates that differences in one individual’s genes or environment, “nature” and “nurture,” could predispose that individual to a long or short life. However, these explanations are radically incomplete. Even in a model system as homogenous as C. elegans, using an isogenic population in a lab-controlled environment, we observe a distribution in lifespans comparable to that seen in outbred human populations. The first part of this dissertation focuses on characterizing this non-genetic, non-environmental variability in the aging …

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Recent Trends And Biases In Mesophotic Ecosystem Research, Veronica Z. Radice, Alejandra Hernández-Agreda, Gonzalo Pérez-Rosales, Ryan Booker, Jessica Bellworthy, Manon Broadribb, Gaby E. Carpenter, Clara Diaz, Ryan J. Eckert, Nicola L. Foster, Johanna C. Gijsbers, Erika Gress, Jack H. Laverick, Valerio Micaroni, Miriam Pierotti, Héloïse Rouzé, Angela Stevenson, Alexis B. Sturm, Pim Bongaerts Dec 2024

Recent Trends And Biases In Mesophotic Ecosystem Research, Veronica Z. Radice, Alejandra Hernández-Agreda, Gonzalo Pérez-Rosales, Ryan Booker, Jessica Bellworthy, Manon Broadribb, Gaby E. Carpenter, Clara Diaz, Ryan J. Eckert, Nicola L. Foster, Johanna C. Gijsbers, Erika Gress, Jack H. Laverick, Valerio Micaroni, Miriam Pierotti, Héloïse Rouzé, Angela Stevenson, Alexis B. Sturm, Pim Bongaerts

School of Biological and Marine Sciences

Mesophotic ecosystems (approx. 30-150 m) represent a significant proportion of the world's oceans yet have long remained understudied due to challenges in accessing these deeper depths. Owing to advances in underwater technologies and a growing scientific and management interest, there has been a major expansion in research of both (sub)tropical mesophotic coral ecosystems and temperate mesophotic ecosystems. Here, we characterize the recent global trends in mesophotic research through an updated release of the 'mesophotic.org' database (www.mesophotic.org) where we reviewed and catalogued 1500 scientific publications. In doing so, we shed light on four major research biases: a gross imbalance in (a) …

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Us Ecological Systems And Climate Adaptation Strategies, Ian Munro Dec 2024

Us Ecological Systems And Climate Adaptation Strategies, Ian Munro

Sustainable Supply Chain Management

This paper is a an introduction and discussion about the various ecosystems of the United States, the different practices of business that hurt them, and how to solve them and create better sustainable resource practices. The ecosystems involve deserts, prairies, and forests which are the main biomes that make up the US. It delves deep in depth of how business affects it and how better sustainability can save it.

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Multi-Antigen Elephant Endotheliotropic Herpesvirus (Eehv) Mrna Vaccine Induces Humoral And Cell-Mediated Responses In Mice, Jessica R Watts, Jennifer L Spencer Clinton, Jeroen Pollet, Rongsheng Peng, Jie Tan, Paul D Ling Dec 2024

Multi-Antigen Elephant Endotheliotropic Herpesvirus (Eehv) Mrna Vaccine Induces Humoral And Cell-Mediated Responses In Mice, Jessica R Watts, Jennifer L Spencer Clinton, Jeroen Pollet, Rongsheng Peng, Jie Tan, Paul D Ling

Faculty, Staff and Students Publications

Background/Objectives: Elephant endotheliotropic herpesvirus (EEHV) causes lethal hemorrhagic disease (HD) in Asian and African elephants in human care and the wild. It is the leading cause of death for young Asian elephants in North American and European zoos despite sensitive diagnostic tests and improved treatments. Thus, there is a critical need to develop an effective vaccine to prevent severe illness and reduce mortality from EEHV-HD. We generated a multi-antigenic EEHV mRNA vaccine to address this need that encodes the EEHV1A-subtype glycoproteins gB, gH, gL, and gO. These conserved proteins are the entry machinery for several herpesviruses in the betaherpesvirus subfamily …

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Aspiration Of Left Atrial Masses Using The Large-Bore Manual Aspiration System: The Aspirate La Procedure, Shaurya Srivastava, Hussam Al Hennawi, Ahmad Abulshamat, Appa Bandi, Mohammed Qintar Dec 2024

Aspiration Of Left Atrial Masses Using The Large-Bore Manual Aspiration System: The Aspirate La Procedure, Shaurya Srivastava, Hussam Al Hennawi, Ahmad Abulshamat, Appa Bandi, Mohammed Qintar

Abington Jefferson Health Papers

Transcatheter mass extraction of left-sided cardiac masses has gained popularity in recent years, with scarce data on effectiveness, safety, and types of devices used. Mostly, left-sided aspirations use mechanical and continuous-flow–mediated devices (the AngioVac [AngioDynamics] and Penumbra systems [Penumbra]). To our knowledge, the use of manual aspiration devices has not been reported yet. Here, we report the first case series on the use of the AlphaVac (AngioDynamics) (a large-bore manual aspiration device) system for left-sided intracardiac masses.

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Distinct Effects Of Extra- And Intracellular Trehalose Supplementation In Freezing Medium On The Post-Thaw Developmental Capacity Of Feline Oocytes, Saengtawan Arayatham, Wirakan Kallayanathum, Panuwat Padungros, Theerawat Tharasanit Dec 2024

Distinct Effects Of Extra- And Intracellular Trehalose Supplementation In Freezing Medium On The Post-Thaw Developmental Capacity Of Feline Oocytes, Saengtawan Arayatham, Wirakan Kallayanathum, Panuwat Padungros, Theerawat Tharasanit

The Thai Journal of Veterinary Medicine

Oocyte cryopreservation is a crucial technique for preserving the genetic material of female cats, yet maintaining post-thaw oocyte developmental competence remains a significant challenge. This study investigated the impact of intra- and extracellular trehalose on the developmental competence of feline oocytes following cryopreservation. In Experiment 1, immature feline oocytes were matured in vitro (IVM) with varying concentrations (0, 1.5, and 3 mM) of intracellular trehalose hexaacetate (Tre-(OAc)6). The matured oocytes were then cryopreserved and thawed prior to in vitro fertilization and embryo culture. Experiment 2 examined the effects of extracellular trehalose supplementation at concentrations of 0, 0.125, 0.25, and 0.5 …

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Medication-Induced Esophageal Injury In Cats And Dogs: A Comprehensive Review, Naowarat Suthamnatpong, Aranya Ponpornpisit Dec 2024

Medication-Induced Esophageal Injury In Cats And Dogs: A Comprehensive Review, Naowarat Suthamnatpong, Aranya Ponpornpisit

The Thai Journal of Veterinary Medicine

Medication-induced esophageal injury (MIEI) is a significant concern in veterinary medicine, affecting the health and well-being of animals undergoing various pharmaceutical treatments. If not addressed promptly, MIEI can lead to severe complications such as esophagitis, esophageal stricture, perforation, and even mortality. This review aims to provide a comprehensive examination of MIEI in veterinary medicine, covering essential aspects such as the basic structure of the esophagus, the epidemiology and etiology of MIEI, and the factors influencing susceptibility. The mechanisms of injury are discussed in detail, focusing on direct mechanical injuries, chemical injuries from medication components, and systemic effects. The review also …

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Interaction Of Cumulus-Oocyte Complex (Coc) Number, Oocyte Quality, And Blastocyst Numbers By Repeated Ovum Pick-Up (Opu) In In Vitro Embryo Production, Sakine Ülküm Çizmeci, Dursun Ali Dinc, Mustafa Numan Bucak, Ömer Faruk Yesilkaya, Muhammed Furkan Ciftci, Mehmet Buğra Kivrak, Ayşe Sari, Hasan Ali Cay, Maide Golbasi, Mustafa Bodu Dec 2024

Interaction Of Cumulus-Oocyte Complex (Coc) Number, Oocyte Quality, And Blastocyst Numbers By Repeated Ovum Pick-Up (Opu) In In Vitro Embryo Production, Sakine Ülküm Çizmeci, Dursun Ali Dinc, Mustafa Numan Bucak, Ömer Faruk Yesilkaya, Muhammed Furkan Ciftci, Mehmet Buğra Kivrak, Ayşe Sari, Hasan Ali Cay, Maide Golbasi, Mustafa Bodu

The Thai Journal of Veterinary Medicine

Ovum pick-up (OPU) is a repeatable technique that is used for the retrieval of large numbers of immature oocytes from the antral follicles of live animals. The aim of the present study was to determine the effect of repeated OPU application on cumulus-oocyte complex (COC) number, oocyte quality, and blastocyst rates. The animal material for the study consisted of 10 Holstein heifers. Heifers selected as donors were administered OPU a total of 9 times on random days of the cycle at 1-week intervals. All antral follicles with a diameter of 2-8 mm were aspirated during the OPU procedure. In vitro …

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Clinical Consideration In Total Intravenous Anesthesia Using Xylazine And Propofol In Calves, Keita Tokimitsu, Momoko Yachida, Wataru Miki, Tadashi Kuramoto, Nanako Mochizuki, Sakura Yoshida, Tadahiro Goto, Yasuhiro Morita Dec 2024

Clinical Consideration In Total Intravenous Anesthesia Using Xylazine And Propofol In Calves, Keita Tokimitsu, Momoko Yachida, Wataru Miki, Tadashi Kuramoto, Nanako Mochizuki, Sakura Yoshida, Tadahiro Goto, Yasuhiro Morita

The Thai Journal of Veterinary Medicine

Surgery must often be performed in fields where only simple equipment and facilities are available for cattle practice, and anesthesia with minimal procedures should be improved for sufficient surgery in the field and on farms. The study aimed to investigate total intravenous anesthesia (TIVA) using xylazine and propofol to improve the anesthesia protocol for field surgeries in calves on farms. Fourteen calves undergoing laparotomy (every seven cases of herniorrhaphy for umbilical hernia repair and cryptorchidectomy) were assigned to this experiment and randomly divided into two groups using TIVA: continuous intravenous infusion with only xylazine (XY, 0.24-0.26 mg/kg/h), and xylazine and …

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Clinical Features And Imaging Characteristics Of Penile Hematoma Mimicking Priapism In A Dog, Yujeong Shin, Dongseok Kim, Daji Noh, Min Jang, Young-Sam Kwon, Sang-Kwon Lee, Kija Lee Dec 2024

Clinical Features And Imaging Characteristics Of Penile Hematoma Mimicking Priapism In A Dog, Yujeong Shin, Dongseok Kim, Daji Noh, Min Jang, Young-Sam Kwon, Sang-Kwon Lee, Kija Lee

The Thai Journal of Veterinary Medicine

A 2-year-old, castrated male Jindo dog presented with 6 days of penile swelling and protrusion, suggesting priapism. Blood gas was analyzed by aspirating the corpus cavernosum to differentiate the type. However, the results were ambiguous. Ultrasound and computed tomography revealed a well-encapsulated mass ventral to the urethra. Magnetic resonance imaging showed a mass (T2-hyperintense, T1-hypointense, with no contrast enhancement) located ventral to the urethra. Cytology revealed only red blood cells, confirming a hematoma. Penile hematoma mimicking priapism was diagnosed. After 11 weeks of glucocorticoid administration, the hematoma and the protruded penis resolved. This case suggests that penile hematoma can be …

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Prevalence Of Coronavirus And Rotavirus In Dairy Calves In North-Central Of Algeria, Dadda Anes, Mohamed Cherif Abdellah, Khelef Djamel Dec 2024

Prevalence Of Coronavirus And Rotavirus In Dairy Calves In North-Central Of Algeria, Dadda Anes, Mohamed Cherif Abdellah, Khelef Djamel

The Thai Journal of Veterinary Medicine

Coronavirus and Rotavirus have been reported as the two main pathogens implicated in neonatal gastroenteritis in calves. The aim of this study is to provide descriptive and analytical epidemiological data and to evaluate the influence of infection with these two viruses on the onset of diarrhea in calves less than 60 days old. In our study, we included 35 dairy cattle farms in the north-central part of Algeria from January 2019 to December 2021. We analyzed 152 samples using the Copro-ELISA test, which revealed a prevalence of 10.53% and 9.87% for Rotavirus and Coronavirus, respectively. The analysis of the results …

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Evaluation Of The Presence Of Sarcocystis Spp. In Dogs Raised In Alpaca Farm Enterprises In Cajamarca, Peru, Milena Ydrogo, María Cabrera, Jennifer L. Cuzcano-Anarcaya, Luis A. Vargas-Rocha, Teófilo Torrel Dec 2024

Evaluation Of The Presence Of Sarcocystis Spp. In Dogs Raised In Alpaca Farm Enterprises In Cajamarca, Peru, Milena Ydrogo, María Cabrera, Jennifer L. Cuzcano-Anarcaya, Luis A. Vargas-Rocha, Teófilo Torrel

The Thai Journal of Veterinary Medicine

The apicomplexans of the genus Sarcocystis are parasites that infect various animal species, including humans. Both dogs and other carnivores can act as definitive hosts of this protozoan. The present study aimed to determine the frequency of Sarcocystis spp. in domestic dogs raised in three alpaca breeding areas in Cajamarca. Random fecal samples were collected from 102 dogs of different ages and both sexes in three locations related to alpaca breeding: Atahualpa Jerusalén Agricultural Workers Cooperative - Cajamarca (N = 35), SAIS Huacraruco - San Juan (N = 33), and Alpacas Project - Foncreagro - Sorochuco (N = 34). The …

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Lessons Learned: Jason Cave, Vincient Arnold, Greg Feldberg Dec 2024

Lessons Learned: Jason Cave, Vincient Arnold, Greg Feldberg

Journal of Financial Crises

Jason Cave was the senior adviser to the chairman of the Federal Deposit Insurance Corporation (FDIC) from 2008 to 2011 and the deputy director of the Division of Complex Financial Institutions at the FDIC from 2011 to 2013. This Lessons Learned summary is based on an interview with Cave held on April 8, 2024. During the interview, Cave discussed the so-called ring-fencing arrangements planned, considered, or executed between various agencies of the US government—the Federal Reserve, Department of the Treasury, and FDIC—and three banks: Wachovia, Citigroup, and Bank of America. These arrangements, sometimes referred to as wraps or risk shields, …

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The Relationship Between Periodontal Disease Of Feline And Oral Core Microbiome, Ziyao Zhou Dec 2024

The Relationship Between Periodontal Disease Of Feline And Oral Core Microbiome, Ziyao Zhou

The Thai Journal of Veterinary Medicine

The microbiome of the oral cavity is complex with the average adult harboring about 50 to 100 billion bacteria which represent about 200 predominant bacterial species. There are a large number of microbes in the oral cavity of the feline, normally beneficial to oral health and safety maintenance. However, when the balance of bacteria lost, it may occur feline stomatitis and periodontitis, which seriously endanger local oral health. Environmental implication, feeding model, age and genetic factors may be main factors affecting oral composition of microbiome. Filifactor alocis, Porphyromonas gingivals, Tannerella forsythia and their interactions are main pathogen that …

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Successful Transcatheter Edge-To-Edge Mitral Valve Repair Via Minithoracotomy In Canine Myxomatous Mitral Valve Disease: Case Report, Anusak Kijtawornrat, Pasakorn Brikshavana, Suphanut Kulabsri, Varit Wijitratanagorn, Nilubol Booncharoensombat, Phanupong Chinnabrut, Wutti Bunjerdsuwan, Natrada Rujivipat, Nakkawee Saengklub Dec 2024

Successful Transcatheter Edge-To-Edge Mitral Valve Repair Via Minithoracotomy In Canine Myxomatous Mitral Valve Disease: Case Report, Anusak Kijtawornrat, Pasakorn Brikshavana, Suphanut Kulabsri, Varit Wijitratanagorn, Nilubol Booncharoensombat, Phanupong Chinnabrut, Wutti Bunjerdsuwan, Natrada Rujivipat, Nakkawee Saengklub

The Thai Journal of Veterinary Medicine

Transcatheter edge-to-edge mitral valve repair (TEER) for the correction of mitral regurgitation (MR) due to myxomatous mitral valve disease (MMVD) stage B1 in a dog by a hybrid intervention technique via minithoracotomy was first reported in Thailand and Southeast Asia. The dog did not show any clinical signs related to congestive heart failure (CHF). Physical examination revealed systolic murmur grade III/VI. Electrocardiographs were recorded and showed normal sinus rhythm. A thoracic radiograph revealed normal size and shape of the heart (VHS 10.9) and diffuse bronchial pattern in the lungs. A definitive diagnosis of MMVD was made by echocardiography. The dog …

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Multidrug-Resistance In Escherichia Coli And Klebsiella Pneumoniae Isolated From Broiler Chickens In Eastern Thailand, Suttitas Tongkamsai, Wachirawit Chatmontee, Kulchai Nakbubpa Dec 2024

Multidrug-Resistance In Escherichia Coli And Klebsiella Pneumoniae Isolated From Broiler Chickens In Eastern Thailand, Suttitas Tongkamsai, Wachirawit Chatmontee, Kulchai Nakbubpa

The Thai Journal of Veterinary Medicine

Broiler chickens have been suggested as an important source of antibiotic resistance Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae). The coinfection of multiple species of bacteria provides a specific ecological niche for the plasmid-mediated exchange of antibiotic-resistance genes. However, there is limited information about antimicrobial resistance (AMR) phenotypes of E. coli and K. pneumoniae isolates from broiler chickens. This study aimed to isolate E. coli and K. pneumoniae from broiler chicken farms in Thailand by observing the antibiotic resistance profiles and detecting the coexistence of these two bacteria. A total of 26 E. coli and 29 …

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Avian Adaptation To Thermal Gradients, Justin Wheeler Baldwin Dec 2024

Avian Adaptation To Thermal Gradients, Justin Wheeler Baldwin

Arts & Sciences Electronic Theses and Dissertations

Life on Earth has adapted to extremely different temperatures worldwide. However, across distant branches of the tree of life, animals in similar temperature environments often share similar phenotypic traits. Specifically, traits that bear on the ratio between an individual’s surface area (e.g. appendage length) and its volume (e.g. body size) are particularly important for temperature regulation and are codified in canonical biogeographical rules. Although these global patterns of finding larger-bodied (Bergmann’s Rule) and shorter-limbed (Allen’s Rule) animals in colder regions are widely upheld, they also show substantial variation. It remains poorly understood why some animals conform to these biogeographical rules …

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Water Quality Assessment Of Three Ponds In The Plaster Creek Watershed, Orin Daspit, Salome Giessmann, Kennedi Pepin, Andrew Slagter, Sydney Wagenmaker Dec 2024

Water Quality Assessment Of Three Ponds In The Plaster Creek Watershed, Orin Daspit, Salome Giessmann, Kennedi Pepin, Andrew Slagter, Sydney Wagenmaker

Student Papers and Reports

Ponds are commonly found in urban areas serving as both an aesthetic and ecological feature. The water quality of these ponds can make important contributions to the overall health of the watershed in which they reside. This study analyzes three ponds within the Plaster Creek Watershed: the Southbridge Condominium Association Pond, the Calvin University Seminary Pond, and the Calvin University Ecosystem Preserve Kettle Swamp. This project aims to provide the Southbridge Condo Association with data that will inform future remediation actions. Using water samples collected over three days, E. coli, pH, nutrients, and total dissolved solids were measured in each …

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Approved Programs 12-17-24, Angela Brock Dec 2024

Approved Programs 12-17-24, Angela Brock

Programs Committee (PC)

No abstract provided.

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Corner Post V. Board Of Governors Of Federal Reserve System, Alexis Karbowicz Dec 2024

Corner Post V. Board Of Governors Of Federal Reserve System, Alexis Karbowicz

Public Land & Resources Law Review

Corner Post v. Board of Governors of the Federal Reserve System resolved a circuit split on when claims against the federal government “accrue” under 28 U.S.C.A. § 2401(a). The Supreme Court clarified whether plaintiffs must file challenges within six years of a regulation’s enactment or may wait until they are directly affected by an agency action, even if that occurs years later. Examining the case’s factual and procedural background provides insight into the relevant regulatory context. The Court’s analysis offers a detailed interpretation of statutory language and establishes principles of claim accrual, alongside the policy considerations of regulatory finality and …

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The Biopiracy Of Traditional Knowledge In United States Patent Law, Hannah Green Dec 2024

The Biopiracy Of Traditional Knowledge In United States Patent Law, Hannah Green

Public Land & Resources Law Review

The United States intellectual property (“IP”) system is deeply intertwined with our country’s history and constitution. t is foundational in favoring young American inventors. George Washington signed the first patent act in 1790 in hopes of promoting the innovation and progress of science and useful arts. Yet, our patent system was also built around the Western tradition of individualism and competition, which failed to recognize the communal nature and traditional knowledge of tribal communities. This disparity allows the biopiracy of traditional knowledge to be lawful. This comment will explore the harmful toll that United States patent law has taken on …

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Organizational Leadership Strategies For Growing Membership In A Start-Up Online Business, Pascale Rheault Dec 2024

Organizational Leadership Strategies For Growing Membership In A Start-Up Online Business, Pascale Rheault

Walden Dissertations and Doctoral Studies

Leaders of small- and medium-sized enterprises (SMEs) play a critical role in driving the global economy; however, online start-ups often face high failure rates within their first year. Some start-up leaders fail to implement effective promotional strategies, hindering their ability to succeed in a competitive market. Grounded in the Baldrige performance excellence framework, the purpose of this qualitative single case study was to explore effective strategies business leaders use to grow membership in an online start-up business. The participants were two senior leaders in the Toronto region’s start-up sector. Data were collected using semistructured interviews as well as a review …

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The Influence Of Heat Therapy On Redox Signaling In Skeletal Muscle, Kimberly Miriam Richard Dec 2024

The Influence Of Heat Therapy On Redox Signaling In Skeletal Muscle, Kimberly Miriam Richard

Theses and Dissertations

Reactive oxygen species (ROS) have been identified as crucial signaling molecules in skeletal muscle adaptations to exercise and signal for protective pathways within the myofiber. Pathological heat stress studies in animals demonstrate the ability of heat to increase ROS production in skeletal muscle. Limited data on the influence of therapeutic heat on ROS production and redox signaling in human skeletal muscle exists in the literature. The purpose of this study was to assess ROS production and redox signaling in human skeletal muscle following an acute, therapeutic bout of heat treatment. We hypothesized that heat would create an oxidized environment within …

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Title Vii & The First Amendment: Perpetuating The Lack Of Asian American Representation In The Entertainment Industry, Mandri Randeniya Dec 2024

Title Vii & The First Amendment: Perpetuating The Lack Of Asian American Representation In The Entertainment Industry, Mandri Randeniya

Loyola of Los Angeles Entertainment Law Review

No abstract provided.

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Fine-Scale Spatial Patterns Of Gelatinous Zooplankton In The Northern Gulf Of Alaska, Hannah E. Kepner Dec 2024

Fine-Scale Spatial Patterns Of Gelatinous Zooplankton In The Northern Gulf Of Alaska, Hannah E. Kepner

Oceanography

The Northern Gulf of Alaska (NGA) is characterized by high variability across spatial and temporal scales. In the NGA, zooplankton are a crucial link between primary production and higher trophic levels. Understanding the mechanisms that structure zooplankton assemblages is important to our overall understanding of ecosystem functioning. Nonetheless, thorough description of zooplankton abundance and distribution patterns is challenging due to the inherent variability and complexity of the marine environment. The study of gelatinous zooplankton is further complicated by the limitations of traditional plankton net sampling methods that are inefficient for the collection of high-resolution spatiotemporal data and often inflict damage …

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Mammalian Trait Evolution: Macroevolutionary And Comparative Genomic Analyses Of Diet And Ursid-Specific Adaptations, Matthew David Pollard Dec 2024

Mammalian Trait Evolution: Macroevolutionary And Comparative Genomic Analyses Of Diet And Ursid-Specific Adaptations, Matthew David Pollard

Electronic Theses and Dissertations Archive

Complex traits such as diet have shaped the evolutionary success of species, driving the diversity of form and function that we observe across the tree of life. My research investigates the genomic and macroevolutionary forces behind diet and other complex traits, revealing how they mediate evolutionary change across Mammalia. I utilized two complementary approaches for understanding the evolution of diet in mammals. First, I created two continuous dietary variables—degree of carnivory and degree of dietary specialization—to quantify the impact of diet on mammalian speciation. I found that degree of carnivory, rather than dietary specialization, significantly influenced speciation, but did not …

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Functional Characterization Of Haloarchaeal Udp-Glucose 4-Epimerase And 3-Hydroxybutyryl-Coa Dehydrogenase Genes In Nicotiana Tabacum, Çi̇ğdem Otur, Sezer Okay, Aslihan Kurt Kizildoğan Dec 2024

Functional Characterization Of Haloarchaeal Udp-Glucose 4-Epimerase And 3-Hydroxybutyryl-Coa Dehydrogenase Genes In Nicotiana Tabacum, Çi̇ğdem Otur, Sezer Okay, Aslihan Kurt Kizildoğan

Turkish Journal of Botany

The objective of the studyAbiotic stress poses a significant threat to plant survival. In response to the challenging conditions, plants have evolved various resistance mechanisms. Recently, genetic strategies have become increasingly prevalent in efforts to enhance abiotic stress tolerance and develop stress-resistant plant varieties. In this study, we employed heterologous expression of two metabolism-related haloarchaeal genes in the Nicotiana tabacum genome to improve its mechanism for salt and drought tolerance.Experimental procedure(s)The U2642 and CL165 genes encoding 3-hydroxybutyryl-CoA dehydrogenase and UDP-glucose 4-epimerase, respectively, were subcloned into the pIPKb004 vector under the control of Cauliflower mosaic virus 35S (CaMV35S) promoter using the …

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Genome-Wide Identification And Characterization Of The Lea Gene Family In Common Bean And The Role Of The Dehydrin Gene Pvhdn3 In Enhancing Salt And Drought Tolerance In Transgenic Tobacco Plant., Gökhan Gökdemi̇r, Zafer Seçgin, Karam Mostafa, Mohamed Farah Abdulla, Musa Kavas Dec 2024

Genome-Wide Identification And Characterization Of The Lea Gene Family In Common Bean And The Role Of The Dehydrin Gene Pvhdn3 In Enhancing Salt And Drought Tolerance In Transgenic Tobacco Plant., Gökhan Gökdemi̇r, Zafer Seçgin, Karam Mostafa, Mohamed Farah Abdulla, Musa Kavas

Turkish Journal of Botany

Global climate change exposes crops to numerous abiotic and biotic stress factors, significantly threatening their growth, development, and overall productivity. Among the various abiotic stresses, salt and drought are the most detrimental, having a severe impact on yield stability. Late Embryogenesis Abundant proteins (LEA) represent a broad and varied class of polypeptides that accumulate in response to cellular dehydration across diverse organisms. Nonetheless, there has been a scarcity of studies on this protein family in common beans prior to this investigation. In this study, we identified 69 members of the LEA gene family in common bean, characterized by conserved LEA …

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