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Development Of Dual-Scan Nuclear Magnetic Resonance (Nmr) Pulse Programs For Spin-Lattice Relaxation Measurements, Zachary Mayes

Doctoral Dissertations

This research develops and refines the Split Inversion Pulse and Recovery (SIP R) methodology for spin-lattice relaxation (T₁) measurements in NMR spectroscopy. SIP R introduces a two-scan difference technique using a split inversion pulse sequence, where the 180° pulse is split into two 90° pulses phase-shifted with respect to each other. This approach simplifies data fitting, requiring only two parameters to extract T₁ values, compared to the traditional inversion-recovery method, which needs three. The SIP-R-DS and SIP-R-S adaptations extend this framework by incorporating selective NMR resonance excitations, enhancing its applicability to cross-polarization experiments and enabling unobstructed NOE measurements. These adaptations …

Novel Nano-Formulations Based On Flash Nanoprecipitation For Ocular Drug Delivery, Lin Qi

Doctoral Dissertations

Effective ocular drug delivery has always been a challenge for clinical and research. Although many nanotechnology-based formulations have been developed and showed great potential in ocular drug delivery, this is far from enough to meet clinical requirements. These studies aimed at the design and synthesis of novel nanoparticles using multi-inlet vortex mixer (MIVM) to improve ocular drug delivery efficiency. The first project involves packaging two different anti-glaucoma drugs, brimonidine (BM) and betaxolol (BX), into solid drug nanoparticles (SDNs) by MIVM, which can achieve both functions, reducing aqueous humor production and promoting aqueous humor efflux. The studies demonstrate that the SDNs …

Design And Synthesis Of Organocatalyts For Efficient Decontamination Of Organophosphate-Based Nerve Agents And Pesticides, Emmanuel Kingsley Darkwah

Doctoral Dissertations

Exposure to organophosphate-based nerve agents and pesticides poses significant health and security threats to civilians, soldiers, and first responders. Despite extensive efforts to develop chemical detoxification agents for use in topical applications on exposed skin surfaces and for intravenous injections, there remains an unmet need for effective, non-hazardous decontaminating agents. The current state-of-the-art decontaminating agent, Dekon-139 (2,3-butanedione oxime, potassium salt), exhibits adverse effects when applied to the skin.

In this study, we designed and synthesized pharmaceutically relevant aminoguanidine-derived aldimines that are relatively non-toxic and substantially more effective at decontaminating nerve agents and pesticides compared to existing agents, and they act …

Supporting Human-Ai Interaction From User Expectations To Mental Models, Harishankar Vasudevanallur Subramanian

Doctoral Dissertations

Explainable AI (XAI) aims to unravel the "black box" nature of AI systems and provide insights into the inner workings that lead to a prediction. However, the best XAI communication varies depending on the individual, task, and broader context. It is challenging to anticipate the best XAI for a particular use case. One strategy is for users to build an appropriate mental model of AI with both prediction and system level XAI. To date, little research has focused on quantitatively measuring users interacting with system-level XAI. This dissertation has three primary contributions. The first contribution is a scoping review paper …

Synthesis Of Graphene Using Carbonaceous Materials In An Ultrasonic Reactor, Paul Chukwuma Ani

Doctoral Dissertations

The synthesis of high-quality graphene from sustainable carbonaceous feedstocks offers an avenue to reduce the environmental and economic costs associated with conventional graphite-based production. This research investigates the co-utilization of biochar and graphite as precursors for graphene fabrication in an ultrasonic reactor. Biochar was produced from biomass via downdraft gasification at 850 °C, yielding a high fixed-carbon, partially graphitized material with favorable surface area and porosity. Graphite, selected for its crystalline structure, was investigated with biochar to assess the influence of precursor composition on exfoliation efficiency, layer thickness distribution, and defect density. Ultrasonic-assisted liquid-phase exfoliation was employed, with process parameters …

Emcreg-International Multidisciplinary Consensus Panel On Management Of Hyperkalemia In Chronic Kidney Disease And Heart Failure, Natalie Kreitzer, Nancy M. Albert, Alpesh N. Amin, Craig J. Beavers, Richard C. Becker, Gregg Fonarow, W. Brian Gibler, Katherine W. Kwon, Robert J. Mentz, Biff F. Palmer, Charles V. Pollack, Iliana L. Piña

Division of Cardiology Faculty Papers

BACKGROUND: Hyperkalemia, generally defined as serum potassium levels greater than 5.0 mEq/L, poses significant clinical risks, including cardiac toxicity and muscle weakness. Its prevalence and severity increase in patients with chronic kidney disease (CKD), diabetes mellitus, and heart failure (HF), particularly when compounded by medications like angiotensin converting inhibitors, angiotensin receptor blockers, and potassium sparing diuretics. Hyperkalemia arises from disruptions in potassium regulation involving intake, excretion, and intracellular-extracellular distribution. In CKD and acute kidney injury, these regulatory mechanisms are impaired, leading to heightened risk. The management of chronic hyperkalemia presents a challenge due to the necessity of balancing effective cardiovascular …

Thinking Artfully With Matter: A Posthuman Enquiry Into The Pedagogical Values Of Sketch-Booking., Melanie Potier

School of Law, Humanities and Social Sciences Theses

Becoming attentive to art practices in terms of what they can do rather than what they are, the writing generates a more tentative-artful engagement with how sketchbooking processes engender more response-able relationship with the world. Exploring the relation between sensation and thought, this exemplification of the speculative potential of force and form, emerges as a powerful resistance to the constraints of the neoliberal education system. Practicing art as immanent doing, Erin Manning’s theory of incipient movement works to develop concepts, such as research-creation, event-time, artfulness and thought in motion, which find expression through the mundanities and ordinary occurrence of the …

Distance Metric Learning Techniques For The Performance Improvement Of Ml-Knn And Ranking-Svm-Based Multi-Label Pattern Classification, Shajee Mohan B. S., Sneha S Mohan

ASEAN Journal on Science and Technology for Development

A multi-label pattern classification system tries to predict the set of class labels of a test example by learning from the training examples with the relevant label sets. Classification that involve datasets having multiple labels found immense of applications in pattern analysis tasks involving image, music and video. A test sample can be labeled to indicate different objects, people, music categories or concepts. Classification problems involving data having multiple labels, have to consider training dataset associated with variety of labels. Multi-label extensions of popular algorithms, kNN and Support Vector Machine (SVM) called Multi-label kNN (ML-kNN) and Ranking-SVM are commonly used …

A First Model Foundation Design Of Wood Pillar In Banjarmasin Swampland, Nursyarif Agusniansyah, Gusti Novi Sarbini, Akbar Rahman, Muhammad Tharziansyah

ASEAN Journal on Science and Technology for Development

Banjarmasin's swampland presents distinct characteristics that make it suitable for constructing homes, but it also requires special attention, especially concerning the foundation. The soil in this area often has extremely low carrying capacity, which poses a significant challenge for construction. Mistakes in choosing construction materials, coupled with mismatched building loads and inadequate foundation functions, often result in foundation failures—a common cause of building collapses. As the complexity and functionality of buildings increase, the need for more thoughtful house design becomes more crucial. The commonly used wooden pile foundation, while popular, has limited load-bearing capacity, necessitating modifications to enhance its strength. …

Potential Of Green Synthesis Of Silver And Gold Nanoparticles For The Management Of Metabolic Associated Steatotic Liver Disease: A Mini Review, Atiqah Suhaili, Ya Chee Lim, Mei Ann Lim, Lee Hoon Lim, Mohammad Mansoob Khan, Monowarul Mobin Siddique

ASEAN Journal on Science and Technology for Development

Metabolic-associated steatotic liver disease is a metabolic disorder with limited pharmacological treatment options and only one approved medication to date. MASLD can be asymptomatic in its earlier stage and hence, prevention of this disease progression is the most effective approach. Recently, green-synthesized nanoparticles, particularly silver (AgNPs) and gold nanoparticles (AuNPs), have gained interest due to their eco-friendly production, biocompatibility, and bioactive properties. This review highlights the biosynthesis of AgNPs and AuNPs using medicinal plant extracts and their reported biological effects relevant to MASLD management including anti-hyperlipidemic, anti-diabetic, antioxidant and anti-inflammatory activities. While findings are promising, further mechanistic studies and preclinical …

Editorial: A Decade Of Apasti – Advancing Regional Prosperity Through Science, Technology And Innovation, Basilios Tsikouras

ASEAN Journal on Science and Technology for Development

A decade after its establishment, APASTI has emerged as a key regional mechanism for promoting science, technology and innovation as drivers of sustainable development, resilience, and shared prosperity in Southeast Asia. This editorial highlights the contributions of APASTI to policy alignment, knowledge exchange, research visibility, and collaborative network-building across ASEAN, while also acknowledging ongoing constraints related to governance, capacity, funding disparities, and uneven regional integration. It introduces a special issue of 14 papers published in AJSTD that collectively evaluate the implementation and impact of APASTI across diverse sectors, including geohazards, energy, materials, health, infrastructure, transport, and information systems. By positioning …

The Effect Of Blanching And Steaming Pretreatment On The Quality Of Durian (Durio Zibenthinus Murr.) Seed Flour, Nabilah Daniel, Rosnah Shamsudin, Mohd Sabri Pak Dek, Jhauharotul Muchlisyiyah, Masmunira Rambli

ASEAN Journal on Science and Technology for Development

Durian (Durio zibethinus Murr.), the "King of Fruits," has seeds that offer nutritional benefits, including high fiber for gut health and high protein for muscle growth. However, natural browning enzymes can limit its use in baking. This study investigates the comparative effects of blanching and steaming durations (5, 10, 15, 20, and 25 minutes) on the color and techno-functional properties of durian seed flour (DSF), providing an optimization-based approach rarely reported for this material.. Durian seeds were sourced from various stalls in Malaysia, washed, soaked in 0.6% sodium metabisulfite, and then blanched or steamed for for varying durations as …

Influence Of Unmanned Aerial Vehicle (Uav) Payloads And Flight Speeds On Pesticide Droplet Deposition: Indoor Testing Rig Study, Siti Amni Ismail, Azmi Yahya, Ahmad Suhaizi Mat Su, Anas Mohd Mustafah, Norhayu Asib

ASEAN Journal on Science and Technology for Development

This study aims to determine droplet deposition resulting from dynamic change in payloads and flight speeds of Unmanned Aerial Vehicle (UAV) during operation. The study was conducted at Universiti Putra Malaysia, Serdang, Malaysia. The Advansia A1 hexacopter was first set to fly at combinations of 3 payloads (3.3, 6.6, and 9.9 kg) with 3 flight speeds (3, 5 and 7 m/s) to collect individual rotor RPM, which will later be used to set the rotors’ speed during indoor testing experiment. During the experiment, actual pesticide (Alosa EC) was used at 0.5% concentration in the spray deposition test. The droplet deposition …

Macro-Ergonomic And Organizational Behavior Mapping For Organic Waste Management Using Hofstede Culture In Semarang, Indonesia : Pca & Sem Analysis Using Smart Pls, Ratih Setyaningrum, Sahana Pramukti, Ravindran Balasubramani

ASEAN Journal on Science and Technology for Development

Waste management has a very close and complex relationship with community behavior and culture . This relationship is two-way: community culture influences how waste is managed, and conversely, waste management practices can shape or change culture. This study to assess the organizational behavior related to organic waste management. Employing a quantitative methodology, data were gathered using the Hofstede Values Survey Module 13 (VSM 13) - closed questionnaire, with 109 Semarang city Community participants responding via a Google Form. The collected data were analyzed utilizing Hofstede's prescribed formula. The next stage is PCA (Principal Component Analysis) and SEM (Structural Equation Modeling) …

Quiet Please! Ethical Considerations On New York City’S War On Noise, Jazlyn Moreno

Student Scholarship

No abstract provided.

Local Food Systems And Sustainability: A Granville Cookbook, Jocelyn Rafter

Student Scholarship

No abstract provided.

“Ask Away!”: A Community Driven Journalistic Advice Column, Tyler K. Thompson

Student Scholarship

No abstract provided.

Exploring The Use Of English In African Literature Through Hiwot Teffera’S Tower In The Sky And Chinua Achebe’S Things Fall Apart, Dibora Merid Tilahun

Student Scholarship

No abstract provided.

The Creation Of An Andean Body: Early Andean State Reliance On A Gendered Division Of Labor, Emma Showalter

Student Scholarship

No abstract provided.

Assessing The Effects Of Low Polyunsaturated Fatty Acids (Pufas) Diets On Priming Immunity In Drosophila Melanogaster, Minh B. Tran Ha

Student Scholarship

No abstract provided.

Ebony Patterson’S …Things Come To Thrive…In The Shedding…In The Molting… (2023) As Intervention, Renee Mcgarry

Publications and Research

This paper examines the use of horticulture and botany in Ebony Patterson's 2023 exhibition at the New York Botanical Garden, …things come to thrive…in the shedding…in the molting… as it relates to the history of NYBG, the Bronx, and the populations that historically and currently reside in the borough. Using plants, blown glass, and glittering styrofoam forms, Patterson productively intervenes in the relationship between an historic, prestigious institution and a changed borough that, since the 1990s, has been walled off from the Garden. The exhibition highlights the tension between community and institution and offers up a new way of understanding …

Xi: Dwelling Writing Thinking: Traces Of Being Songs Of Elduvík Hölderlin’S “In Lovely Blue…” Remembrance The Ister, Charles S. Taylor

Wine Journey: Tasting Dwelling Learning at The Kitchen Table

Lieblicher Cousin Holz / Beloved cousin Holz, welcome once again to my Gehäus! 1 2Please make yourself comfortable on this bench beside me. Remembered conversations bring us back here. New questions to share. Neither of us has a guess where we will ramble during the adventure. Thinking about your beloved Ister / Donau / Danube flowing through the Schwarzwald / Black Forest we found our way, unexpectedly, to Kant’s Erhabene / Sublime. Only after making a visit north of Norway to Svalbard. Der Ister, begins with you calling for daylight allowing you to carefully, reverently observe what will present itself …

The Special Issue “The 20th Anniversary Of Pharmaceuticals—Multi-Targeted Natural Products As Therapeutics” Editorial—Multi-Targeted Therapeutics From Natural Sources: What Do We Know?, Elena Y. Enioutina, Katheleen M. Job, Catherine M.T. Sherwin

Pediatrics Faculty Publications

Herbal and marine products in the form of extracts, infusions, and decoctions have been used for centuries in folk and traditional medicine. Preparations typically contain multiple biologically active compounds. The World Health Organization (WHO) estimated that about 65% of consumers worldwide use natural remedies containing bioactive molecules to treat various diseases [1]. Most single-molecule drugs of natural origin were developed in the middle of the 20th century through the active screening of natural products for bioactive molecules [2]. Examples include artemisinin, cyclosporine, taxol, doxorubicin, and many others. However, at the beginning of the 21st century, we saw a decline in …

Two-Eyed Seeing Into Shipwrecks: Maritime Microscopy In The South Carolina Lowcountry, Sara A. Rich, Kayla Raimondi, Hannah Herness

Honors College Faculty Publications

By enhancing methods for how archaeology can contribute to the study of multi-species shipwrecks (or shipwreck ecology), this paper reconsiders the function of non-functioning ships and boats from anti-colonial and Native American perspectives. In partnership with the Waccamaw Indian People and the Indigenize SC Education Task Force, wood samples from several submerged wreck sites in a blackwater tidal river in the Lowcountry of South Carolina (USA) were analyzed for their archaeological potentials and for their potential to disclose the performance of individual sites within the underwater ecosystems of which they are a part. In turn, this information offers the opportunity …

Gene Expression And Dna Methylation Changes In Response To Hypoxia In Toxicant-Adapted Atlantic Killifish (Fundulus Heteroclitus), Neelakanteswar Aluru, Yaamini R. Venkataraman, Christopher S. Murray, Veronica Depascuale

Biology

Coastal fish populations are threatened by multiple anthropogenic impacts, including the accumulation of industrial contaminants and the increasing frequency of hypoxia. Some populations of the Atlantic killifish (Fundulus heteroclitus), like those in New Bedford Harbor (NBH), Massachusetts, USA, have evolved a resistance to dioxin-like polychlorinated biphenyls (PCBs) that may influence their ability to cope with secondary stressors. To address this question, we compared hepatic gene expression and DNA methylation patterns in response to mild or severe hypoxia in killifish from NBH and Scorton Creek (SC), a reference population from a relatively pristine environment. We hypothesized that NBH fish would show …

Impacts Of Ramadan Fasting During Pregnancy On Pregnancy And Birth Outcomes: An Umbrella Review, Abdullah Al-Taiar, Md Estiar Rahman, May Salama, Ali H. Ziyab, Wilfried Karmaus

Epidemiology, Biostatistics, & Environmental Health Faculty Publications

Background

Despite a large number of primary research studies, and systematic and narrative reviews, there is no consensus on the impact of fasting during Ramadan while pregnant on pregnancy and birth outcomes. Currently, there is no evidence-based guideline for Muslim women regarding Ramadan fasting during pregnancy and clinicians cannot provide firm recommendations.

Objectives

To review the current evidence regarding the impact of Ramadan fasting during pregnancy on pregnancy and birth outcomes.

Search Strategy

We conducted an umbrella review of all systematic and narrative reviews examining the impacts of fasting during Ramadan while pregnant on pregnancy and birth outcomes by searching …

The Key Revolutionary Element: The Development Of Russia’S Military And The Vitality Of The Russian Soldier To Revolution, Max C. Jones

Tenor of Our Times

This paper looks at the substantial role the Russian Military played in the events leading up to and during the February Revolution in 1917 in Russia. It looks at the military history of Russia prior to the February Revolution (from Peter the Great-Nicholas II) and how certain decisions and events in that timespan created a military that was completely unprepared for the total war of WWI. The paper takes closer looks at the Crimean War and the Russo-Japanese War/1905 Revolution, in which significant changes in the military occurred but, as is seen in the outcome of WWI, were not enough …

Annual Report 2023-2024: Student Life & Development, Denise Mcdowell

Annual Reports

Student Life and Development (SLD) professionals at Winona State University (WSU) deliver programs, services, and activities that support students' academic achievement, social development, and well-being in the timely pursuit of their educational goals. The 2023-2024 SLD Annual Report provides information from the following departments: Admissions, Community Engagement, Conduct & Citizenship, Counseling and Wellness Services, Dean of Students, Equity & Inclusion Excellence, Health & Wellness Services, Housing & Residence Life, Integrative Wellness, Student Union & Activities, TRIO Student Support Services, the Warrior Hub, and the Warrior Success Center.

Income, Education, And Family Structure: Drivers Of Teen Pregnancy In Rural And Urban Ohio, Adam Klauck, Maggie Stiefel, Catherine Wilson

Scholarship in Medicine - All Papers

Teen birth rates in Ohio have been declining; however, due to the potential adverse ramifications of any teen birth, for either the mother or the child, understanding the strongest predictors of teen birth rates in Ohio will allow physicians to preventatively care for their young female population. Our objective was to identify some qualitative factors that best indicate the environment in which a teenage pregnancy is most likely to occur, giving special attention to the difference between rural and urban environments. Relevant data was obtained from County Health Rankings and Roadmaps. This study used qualitative methods and SPSS to analyze …

Inside The Alchemical Interior: Remedios Varo’S Reinvention Of The Artist’S Studio, Jacquelyn D. Shadday

SPARK Symposium Presentations

No abstract provided.