Digital Commons Network^™

Tilapia Fish Collagen: Potential As Halal Biomaterial In Tissue Engineering Applications, Norhidayu Muhamad Zain, Mohammad Naqib Hamdan

Nusantara Halal Journal

Collagen is a natural bioactive polymer widely utilized in tissue engineering applications due to its biocompatibility and biodegradability. Collagen derived from mammalian sources such as porcine and bovine is commonly used as biomaterials. However, due to religious concerns, the halal status of collagen must be taken into consideration. Since most of the mammalian collagen is hampered by its haram origins, marine collagens are widely investigated as alternatives for mammalian collagen in tissue engineering applications. Even though marine collagens are safe and easy to extract, these sources of collagen are hindered by their low denaturing temperature. Tilapia fish (Oreochromis niloticus) has …

Technology Facilitation Assessment For Malaysia Halal Quality Assurance For Food And Beverages, Consumer Goods, Logistics, And Cosmetics Industry, Zuhra Junaida Mohamad Husny Hamid, Mohd Iskandar Illyas, Farahwahida Mohd Yusof

Nusantara Halal Journal

This study aimed to identify the appropriate characteristics of assistive technology to facilitate the quality control process in halal industry segments, namely, food and beverages, consumer goods, logistics, and cosmetics. For this purpose, four separate research projects were conducted to cover these four different industry segments. This paper combined the findings and provided a compilation of all the results. Questionnaire surveys were distributed during the 13th Malaysian International Halal Showcase (MIHAS 2016) as the pilot study. Main data collection was done in the industry in Johor in the southern part of Malaysia. The seven elements of technology characteristics selected for …

Exploring Factors Of Choosing Halal Cosmetics Among Cosmetics Entrepreneurs In Malaysia, Alina Shamsuddin, Farahwahida Mohd Yusof, Nur Syazwina Uzma Sulaiman

Nusantara Halal Journal

Halal cosmetics is expanding well in the manufacturing sector. It has gained the government’s attention to support its development. Generally, the halal industry has been divided into seven sectors, which are food services, consumer goods, financial, pharmaceutical, cosmetics, halal logistics, and tourism. This study attempts to address the influencing factors for choosing halal cosmetics among cosmetics entrepreneurs. The researcher adopts the quantitative method to gather data from the respondents. A random sampling technique was used. The findings indicate that the awareness among young halal cosmetics entrepreneurs is very high, and there are high consumptions of halal cosmetics among consumers that …

Exploring The Issues And Challenges In Malaysian Cosmetic Halal: A Theoretical Framework, Alina Shamsuddin, Farahwahida Mohd Yusof

Nusantara Halal Journal

Halal Industry in Malaysia has been prevalent in the manufacturing sectors and has earned the government's concern in supporting its development. The Halal Industry sector has been considered as one of the leading contributors to Malaysian economy development in the future. This is due to the fact that the market of Halal products is reasonable to Muslims and has received pervasive attention from non-Muslims consumers who consider Halal commercialism. Halal industry has been categorized into seven sectors, which are cuisine, goods, financial, pharmaceutical, cosmetics, logistics, and tourism businesses. However, much attention has been given to issues and challenges to food …

Anticipating Human Resource Development Challenges And Opportunities In ‘Halal Supply Chains’ And ‘Halal Logistics’ Within Asean, Adam Voak, Brian Fairman

Nusantara Halal Journal

The increasing global economic importance of the Association of South-East Asian Nations (ASEAN), is creating new cultural challenges for participating governments. These challenges are clearly impacting on Human Mobility and Human Capability Development within the trading bloc. Development challenges are particularly evident in supply chains, where new knowledge, skills, and attitudes are needed to ensure respect for Halal services and the provenance of Halal products as they are traded across the region. While reflecting on this issue, this paper looks closely at the implicit and explicit challenges and opportunities in building culturally relevant ASEAN ‘Human Capabilities’ along increasingly globalized supply …

Outcomes In Single Versus Two-Stage Surgical Stabilization Of Complex Bilateral Chest Wall Injury: A Single-Center Experience., Alexis A Schweibinz, Jaya S Varre, Anna Graham, William B Devoe

Surgery Articles

INTRODUCTION: Surgical stabilization of rib fractures (SSRF) continues to show benefit for severe chest wall injury (CWI) with improvement in morbidity and mortality following stabilization. Complex bilateral injuries pose a clinical and technical challenge. Currently, there is no formal recommendation for an approach to repair such injuries, whether that be bilateral SSRF within the index case or staged repair. We sought to describe our institutional experience with this subset of patients, identify factors that may influence the decision to pursue single- versus two-stage procedures, and assess the potential benefit of combined bilateral SSRF during the index operation.

METHODS: A retrospective, …

Egypt Under Construction: Spectacle, Surprise, And The Politics Of Megaprojects, Grace E. Payne

Geography Undergraduate Senior Theses

No abstract provided.

They, The People, Ammel Sharon

Socio-Legal Review

This essay engages with Rohit De and Ornit Shani’s Assembling India’s Constitution by situating it within a broader conceptual history of “the people.” While the book offers a compelling account of participatory constitution-making, the essay suggests that it opens up further questions about the conceptual and historical conditions shaping the people as a political subject. Drawing on contemporary political theory on populism, the essay explores how politics invokes the people through affective and performative practices alongside constitutional forms.

Endoplasmic Reticulum-Resident Α-Glucosidase Ii Drives Non-Small Cell Lung Cancer Progression Via Regulation Of Secretory Glycoproteins, Shike Wang, Na Ding, Angelo Chen, Derrick Cardin, Yuting Xu, Kate Grimley, William K. Russell, Jun Xu, Jonathan M. Kurie, Guan Yu Xiao, Xiaochao Tan

Markey Cancer Center Faculty Publications

Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-related mortality worldwide, yet its molecular drivers are not fully defined. Emerging evidence highlights the importance of tumor-stroma interactions mediated by secreted glycoproteins. However, the mechanisms by which cancer cells regulate the secretion of these protumorigenic proteins remain largely unknown. Endoplasmic reticulum-resident (ER-resident) N-glycan-processing enzymes regulate proper protein folding, a prerequisite for glycoproteins to exit the ER and undergo secretion. By evaluating their prognostic significance in lung tumors and conducting functional screening in lung cancer cells, we identify α-glucosidase II (α-Glc II) as a key regulator of NSCLC progression. α-Glc …

From Peril To Perseverance: Dr. Arthur C. Parker And The Seneca Arts Project, Brennan Ciccolone

Binghamton University Undergraduate Journal

Like many Native people, the Haudenosaunee were subjected to culturcide and assimilation using residential schools like the Thomas Indian School in the late 19th and early 20th century. During this time, in 1925, the Seneca archaeologist Dr. Arthur C. Parker was hired as the director of the Rochester Museum and Science Center. Parker used his museum position to uplift and preserve Haudenosaunee arts and culture. This paper focuses on his Seneca Arts Project (1935-1941), which gathered art and artifacts from both ancient and contemporary Haudenosaunee members. This project explores how Parker’s work was used to help revitalize and honor Native …

Gunk - Genetic Underwater Nucleic-Acid Collector, Kay Hall, Harumy Miura, Isaac Carlos Hernandez-Nguyen, Oscar Emilio Alvarado Flores

Interdisciplinary Design Senior Theses

Environmental DNA sampling is a powerful and minimally invasive tool for biodiversity assessment and species monitoring. However, existing environmental DNA collection systems are costly, difficult to deploy at depth at low cost and with small teams, non-standardized, and inaccessible to non-technical users. This report presents GUNK, the Georeferenced Underwater Nucleic-acid Kollector, a submersible environmental DNA sampler developed in collaboration with ConservationXLabs and the Santa Clara University Robotics Systems Laboratory. GUNK is designed to address three primary goals: reaching sampling depths unachievable by existing low-cost solutions, reducing the financial barrier associated with environmental DNA research, and ensuring the system is easily …

Necessary Biosafety Precautions For Patented Gmos: Ramifications Of Inconsistent Parties Between The Cartagena Protocol And Trips Agreement, Lauren Clements

Brooklyn Journal of International Law

Genetically Modified Organisms (“GMOs”) compose a class of potentially patentable biotechnology that are prominent in international markets. Developed countries like the United States, function as leading producers of these patented GMOs and therefore play a significant role in their development and transnational export. Minimum protections for these forms of biotechnology are outlined in the Agreement on Trade-Related Aspects of Intellectual Property Rights (“TRIPS Agreement”), which permits the patenting of GMOs that ultimately enter the stream of international commerce. Notwithstanding the potential risks GMOs present to the environment, public health, and the economy, the TRIPS Agreement fails to address any form …

Back To Intent: Revamping California’S Flagship Environmental Legislation And Tackling The Rise Of The “Super-Commuter”, Jordan Q. Davis

San Diego Journal of Climate & Energy Law

The passage of the California Environmental Quality Act (CEQA) in 1970 has long been considered a watershed moment in the evolution of government participation in environmental issues. In the years since, CEQA has played a pivotal role in protecting Californians’ access to the beautiful nature offered by the Golden State. However, the very regulation that has been repeatedly relied upon to breathe clean air and drink clean water may very well be an instrument upon which Californians could return to smog-ridden skies. In this regard, CEQA’s biggest vulnerability may come from a most unexpected place: its strength.

The tools by …

Soaring To New Heights Through The Lens Of The Scarlet Macaw–A Post-Loper Bright Interpretation Of The Endangered Species Act’S “Significant Portion Of Its Range” For A Climate-Driven “Foreseeable Future”, Kathryn Wood

San Diego Journal of Climate & Energy Law

This Comment will argue for particular interpretations of “significant portion of its range” and “foreseeable future” under the ESA to prioritize species preservation in the face of climate change.

The analysis begins by describing key aspects of the ESA, including its historical background, its conceptual definitions, its prescribed method for determining endangered species and threatened species, its listing process, and critical habitat requirements. This Comment then discusses climate change as a source of threat and endangerment “within the foreseeable future,” and whether acts worsening climate change can constitute an unlawful taking. Next, this Comment considers how the Supreme Court’s decision …

Notch1 Acts As A Tumor Suppressor That Induces Early Differentiation In Head And Neck Cancer, Chenfei Huang, Shhyam Moorthy, Qiuli Li, Kazi M Ahmed, Kalil Saab, Defeng Deng, Jiping Wang, Xiayu Rao, Jiexin Zhang, Yuanxin Xi, Jing Wang, Zhiyi Liu, Noriaki Tanaka, David A Wheeler, Eve Shinbrot, Rami Saade, Curtis R Pickering, Tong-Xin Xie, Adel K El-Naggar, Abdullah A Osman, Kunal Rai, Patrick A Zweidler-Mckay, John V Heymach, Lauren A Byers, Faye M Johnson, Vlad C Sandulache, Jeffrey N Myers, Pedram Yadollahi, Mitchell J Frederick

Faculty, Staff and Students Publications

Inactivating NOTCH1 mutations in head and neck squamous cell carcinoma (HNSCC) were described over a decade ago, suggesting a tumor suppressor function - unlike its oncogenic role in other tumors. Today, much debate persists regarding a putative oncogenic role in HNSCC as well, with reports that NOTCH1 signaling drives tumor growth and a cancer stem cell (CSC) phenotype. In this work, comprehensive experiments unequivocally demonstrate that NOTCH1 is a tumor suppressor in HNSCC regardless of mutation or activation status and that it reduces CSC frequency. We developed a signature of NOTCH1 activation showing the pathway is associated with very early …

Rolling-Shutter Image Skew As A Visual-Inertial Motion Signal In Imu-Synchronized Multimodal Capture, Clifford T. Smyth

Defensive Publications Series

In a sensor system that records a rolling-shutter image stream together with a synchronized, higher-rate inertial measurement unit (IMU) stream, the intra-frame geometric skew produced by rolling-shutter readout is treated not as an artifact to be removed but as a usable, temporally structured motion signal. Because a rolling-shutter frame exposes its rows sequentially, the frame encodes camera and scene motion over the readout interval. When the frame is time-correlated with inertial data at sufficient resolution, the inertial stream can be used to estimate the camera motion during readout, which in turn supports two complementary representations of each frame: (1) an …

Otologic Manifestations Of Temporomandibular Disorders, Fatemeh Ebrahimi, Ali Akbar, Vivian Jin, Vivian F Kaul, Craig B Pearl

Faculty, Staff and Student Publications

Background/Objectives: Temporomandibular disorder (TMD) affects a third of the adult population and has been associated with otologic symptoms. These symptoms are frequently misattributed to primary otologic diseases, leading to delays in diagnosis and treatment. This review aims to summarize the reported prevalence, proposed pathophysiologic mechanisms, and management strategies of otologic manifestations in patients with TMD.

Methods: A literature review was conducted using the MeSH terms "temporomandibular joint disease" and "otologic symptoms." Five additional searches were performed using "temporomandibular disease/dysfunction" combined with each of the five most common otologic symptoms. Meta-analyses, randomized controlled trials, reviews, and systematic reviews were …

Intramuscular Nad⁺ Therapy And Neuroenergetic Symptom Modulation: An Exploratory Retrospective Human Pilot Study, Zachary J. Dickey Do, Kirtan Patel Bs, Randy Aldret Edd, Cscs, Atc, Navneet Sharma Md, Glenn Goodwin Do

Journal for Sports Neuroscience

Abstract

Background: Nicotinamide adenine dinucleotide (NAD⁺) is a central regulator of neuronal energy metabolism, mitochondrial function, and axonal integrity. Following mild traumatic brain injury (mTBI) and repetitive subconcussive exposure, neurons undergo a neurometabolic crisis characterized by impaired oxidative phosphorylation, increased ATP demand, and depletion of intracellular NAD⁺ pools. Pre clinical models demonstrate that NAD⁺ depletion contributes to central energy dysregulation, cognitive dysfunction, and axonal and neuronal degeneration through disruption of NAD⁺-dependent pathways including SIRT1-mediated mitochondrial resilience, PARP1-driven NAD⁺ consumption, and SARM1-associated axonal breakdown. Despite growing preclinical evidence supporting NAD⁺based neuroprotection, human clinical data remains absent.

Methods: A real-world clinical pilot …

Entering The Villa: Love Island Usa Season 7 As A Site For Neoliberal Prosumption, Laura Cunningham

CLAMANTIS: The MALS Journal

No abstract provided.

Three Nights, Andrew Moore

CLAMANTIS: The MALS Journal

No abstract provided.

Dolmen, Keehan White

CLAMANTIS: The MALS Journal

No abstract provided.

George Macdonald’S Spiritually Prophetic Imagination, Michael Phillips

North Wind: A Journal of George MacDonald Studies

No abstract provided.

The Legacy Of Thomas Chalmers In George Macdonald’S Prophetic Imagination, Joyce Mcpherson

North Wind: A Journal of George MacDonald Studies

No abstract provided.

Christian Doctrine In George Macdonald’S The Princess And The Goblin, Mariah Sky Franklin

North Wind: A Journal of George MacDonald Studies

No abstract provided.

A Christian Romantic In Context: The Theological Environment Of George Macdonald’S Scotland, Daniel Hubin

North Wind: A Journal of George MacDonald Studies

No abstract provided.

Seeing From Women’S Points Of View: The Female Sight And Body In Lilith, Ayumi Kumabe

North Wind: A Journal of George MacDonald Studies

No abstract provided.

Virtual Patient-Specific 3-Dimensional Specimen Maps For Adjuvant Radiation Therapy Planning In Mucosal Head And Neck Squamous Cell Carcinoma, Whitney Jin, Michael C. Topf, Marina Aweeda, Kavita Prasad, Olivia Prosak, Sindhura Sridhar, Zachary Kohutek, Sean All, D. W. Nathan Kim, Anthony Cmelak, Ryan Whitaker, Alexander Langerman, Kyle Mannion, Melanie Hicks, Sarah Rohde, Robert Sinard, Eben Rosenthal, Natalie A. Lockney

Department of Otolaryngology - Head and Neck Surgery Faculty Papers

PURPOSE: Adjuvant radiation therapy planning for mucosal head and neck squamous cell carcinoma is challenging due to postoperative anatomic changes, contributing to variability in clinical target volume (CTV) delineation and risk of geographic miss or unnecessary dose expansion. Patient-specific 3-dimensional (3D) specimen maps may offer a novel approach to improve the localization of high-risk margins and facilitate multidisciplinary communication.

METHODS AND MATERIALS: In this prospective, noninterventional feasibility study, 3D scanning and virtual pathologic mapping of surgical specimens were performed as part of routine pathologic processing. Annotated 3D maps were integrated into the radiation therapy planning workflow and reviewed by the …

Viewing Machines, Janos Cseh

Theses and Dissertations

By sifting through personal memories, the contemporary media landscape, and seeing the world through the lens of painting, Cseh asks what it means to understand information through images.  The artist unpacks the interwoven relationships between images and memory, feeling and seeing, and the difficulty of seeking truth through an analysis of his paintings.

The Three Sisters And Soil Health (Lesson 1), Mara Johnson, Madhav P. Nepal, Jiyul Chang

iLEARN Teaching Resources

In this lesson, students will begin a week-long unit on soil health that is connected to the chapter The Three Sisters from the book Braiding Sweetgrass by Robin Wall Kimmerer. Students will begin the week by reading the chapter and answering discussion questions, and each subsequent day will build on this introduction with project-based learning activities. This module is designed to bridge traditional Indigenous knowledge with primary scientific inquiry, allowing students to explore soil nutrients, polycultures, and agricultural health in a way they can apply to their own lives and local food sovereignty efforts on the Rosebud Reservation.

Soil Health Analysis (Lesson 2), Mara Johnson, Madhav P. Nepal, Jiyul Chang

iLEARN Teaching Resources

In this lesson, students will build on the previous lesson (reading and analyzing the Three Sisters chapter from Braiding Sweetgrass) by experimenting on soil in their schoolyard. Students will collect soil samples from multiple locations around their school grounds and evaluate soil texture, structure, infiltration, color, organic matter, and pH. Students Through field observations and laboratory analysis, students examine how soil characteristics influence plant growth and ecosystem health. Students connect modern soil science with Indigenous agricultural knowledge, particularly the Three Sisters planting system described in Braiding Sweetgrass by Robin Wall Kimmerer. By exploring how healthy soil supports sustainable agriculture, …