Digital Commons Network^™

Agricultural Producers' Motivations And Challenges With Improving Soil Health In Utah, Peggy Petrzelka, Jessica Ulrich-Schad, Matt Yost, Jenae Dean, Tony Richards, Kristy Davis

All Current Publications

The Utah Soil Health Program (USHP) developed a five-year project to increase understanding of how best to implement soil health practices into Utah’s diverse farming systems. Fifteen producers were selected to participate in the USHP On-Farm Soil Health Demonstration Project. During 2022, the trial’s first year, the participating farmers and ranchers were interviewed. We begin by discussing participant demographics and operation characteristics. Next, we turn to challenges the producers faced in implementing soil health practices in the IMW and then turn to motivations for the producers to enroll in the USHP trial. This will help (1) document what is currently …

Root Decomposition And Nutrient Dynamics In Multifunctional Forage-Biomass Buffer-Strip Systems, Helen C.S. Amorium, Amanda J. Ashworth, Taylor C. Adams, Mary C. Savin, Philip A. Moore Jr

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Perennial crops are thought as a solution for enhancing food security and providing ecosystem services under a changing climate, including forage-biomass production, reduced erosion and nutrient leaching, and soil C accumulation. However, the drivers of root decomposition and C allocation in perennial multifunctional forage-biomass buffer-strips as affected by fertility management are poorly elucidated. Thus, study objectives were to assess root decomposition and soil CO2 efflux on switchgrass (Panicum virgatum L.), eastern gamagrass (Tripsacum dactyloides L.), silphium (Silphium integrifolium Michx.), and intermediate wheatgrass Kernza (Thinopyrum intermedium [Host] Barkworth & D.R. Dewey) treated with poultry litter (PL) relative to the unfertilized control. …

Grass Weed Control And Rice Response With Tetflupyrolimet-Containing Programs, Mason C. Castner, Jason K. Norsworthy, Thomas R. Butts, Trenton L. Roberts, Nick R. Bateman, Travis R. Faske

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Tetflupyrolimet is the first herbicide with a novel site of action (SOA) labeled PRE and early POST for use in agronomic crops to be labeled in the last three decades. Direct-seeded paddy rice field experiments were conducted near Stuttgart, AR, on a silt loam soil and near Keiser, AR, on a clay soil to evaluate tetflupyrolimet-containing herbicide programs in comparison to commercial standards in conventional, imidazolinone-resistant, and quizalofop-resistant rice systems. Additionally, a furrow-irrigated rice experiment was conducted near Colt, AR, and Keiser to ensure weed control with clomazone and tetflupyrolimet mixtures compared to commercial standards. Twelve commonly planted rice cultivars …

Lipid Nanoparticles Deliver Dna-Encoded Biologics And Induce Potent Protective Immunity, Dafei Chai, Junhao Wang, Jing Ming Lim, Xiaohui Xie, Xinfang Yu, Dan Zhao, Perry Ayn Mayson Maza, Yifei Wang, Dana Cyril-Remirez, Ken H Young, Yong Li

Faculty, Staff and Students Publications

Lipid nanoparticles (LNPs) for mRNA delivery have advanced significantly, but LNP-mediated DNA delivery still faces clinical challenges. This study compared various LNP formulations for delivering DNA-encoded biologics, assessing their expression efficacy and the protective immunity generated by LNP-encapsulated DNA in different models. The LNP formulation used in Moderna's Spikevax mRNA vaccine (LNP-M) demonstrated a stable nanoparticle structure, high expression efficiency, and low toxicity. Notably, a DNA vaccine encoding the spike protein, delivered via LNP-M, induced stronger antigen-specific antibody and T cell immune responses compared to electroporation. Single-cell RNA sequencing (scRNA-seq) analysis revealed that the LNP-M/pSpike vaccine enhanced CD80 activation signaling …

Infiltrating Plasma Cells Maintain Glioblastoma Stem Cells Through Igg-Tumor Binding, Jiancheng Gao, Danling Gu, Kailin Yang, Junxia Zhang, Qiankun Lin, Wei Yuan, Xu Zhu, Deobrat Dixit, Ryan C Gimple, Hao You, Qian Zhang, Zhumei Shi, Xiao Fan, Qiulian Wu, Chenfei Lu, Zhangchun Cheng, Daqi Li, Linjie Zhao, Bin Xue, Zhu Zhu, Zhe Zhu, Hui Yang, Ningwei Zhao, Wei Gao, Yingmei Lu, Junfei Shao, Chuandong Cheng, Dapeng Hao, Shuo Yang, Yun Chen, Xiaoming Wang, Chunsheng Kang, Jing Ji, Jianghong Man, Sameer Agnihotri, Qianghu Wang, Fan Lin, Xu Qian, Stephen C Mack, Zhibin Hu, Chaojun Li, Michael D Taylor, Yan Li, Nu Zhang, Jeremy N Rich, Yongping You, Xiuxing Wang

Faculty, Staff and Students Publications

Glioblastoma is a highly aggressive primary brain tumor with glioblastoma stem cells (GSCs) enforcing the intra-tumoral hierarchy. Plasma cells (PCs) are critical effectors of the B-lineage immune system, but their roles in glioblastoma remain largely unexplored. Here, we leverage single-cell RNA and B cell receptor sequencing of tumor-infiltrating B-lineage cells and reveal that PCs are aberrantly enriched in the glioblastoma-infiltrating B-lineage population, experience low level of somatic hypermutation, and are associated with poor prognosis. PCs secrete immunoglobulin G (IgG), which stimulates GSC proliferation via the IgG-FcγRIIA-AKT-mTOR axis. Disruption of IgG-FcγRIIA paracrine communication inhibits GSC proliferation and self-renewal. Glioblastoma-infiltrating PCs are …

Identification And Characterization Of A Novel Pavlovskyella (Acari: Argasidae) From Chile, Parasite Of The Culpeo Fox (Lycalopex Culpaeus), Sebastián Muñoz-Leal, Alexander R Kneubehl, Karen Ardiles, Catalina Parragué-Migone, Ignacio Troncoso-Toro, Pablo Oyarzún-Ruiz, Job E Lopez

Faculty, Staff and Students Publications

Soft ticks (Argasidae) of the subgenus Pavlovskyella Pospelova-Shtrom are worldwide distributed parasites of medical importance. However, the systematics of the subgenus are currently under debate because genetic data shows that the group is paraphyletic. Meanwhile, species of Pavlovskyella continue to be discovered. In this study a novel species of the subgenus is described from specimens collected on a fox in central Chile. The larva of this new species differentiates from other Pavlovskyella spp. by having the following combination of characters: subpyriform dorsal plate; 15 pairs of setae, 7 anterolateral, 3 central, and 5 posterolateral, and hypostome with denticles in the …

Meta-Analysis Of Dedicated Vs Off-Label Transcatheter Devices For Native Aortic Regurgitation, Sahar Samimi, Taha Hatab, Chloe Kharsa, Safi U Khan, Rody G Bou Chaaya, Fatima Qamar, Joe Aoun, Syed Zaid, Nadeen Faza, Marvin D Atkins, Stephen H Little, William A Zoghbi, Michael J Reardon, Neal S Kleiman, Sachin S Goel

Faculty, Staff and Students Publications

Background: Transcatheter aortic valve replacement (TAVR) for high surgical risk patients with severe native aortic regurgitation (AR) presents unique challenges. Dedicated devices such as the JenaValve (JenaValve Technology) and J-Valve (JC Medical Inc) show promising results in addressing these challenges.

Objectives: This study compares the safety and efficacy of dedicated vs off-label devices among high surgical risk patients with pure native AR.

Methods: We systematically searched PubMed, EMBASE, and Cochrane Central Register of Controlled Trials through July 11, 2024, for studies on TAVR among patients with pure severe native AR. The primary endpoint was 30-day all-cause mortality. Secondary endpoints were …

Daily Glucocorticoids Promote Glioblastoma Growth And Circadian Synchrony To The Host, Maria F Gonzalez-Aponte, Anna R Damato, Tatiana Simon, Nigina Aripova, Fabrizio Darby, Myung Sik Jeon, Jingqin Luo, Joshua B Rubin, Erik D Herzog

2020-Current year OA Pubs

Glioblastoma (GBM) is the most common primary malignant brain tumor in adults with a poor prognosis despite aggressive therapy. Here, we hypothesized that daily host signaling regulates tumor growth and synchronizes circadian rhythms in GBM. We find daily glucocorticoids promote or suppress GBM growth through glucocorticoid receptor (GR) signaling depending on time of day and the clock genes, Bmal1 and Cry. Blocking circadian signals, like vasoactive intestinal peptide or glucocorticoids, dramatically slows GBM growth and disease progression. Analysis of human GBM samples from The Cancer Genome Atlas (TCGA) shows that high GR expression significantly increases hazard of mortality. Finally, mouse …

Economic Analysis Of Hay And Corn Production At Morehead State University’S Derrickson Agricultural Complex, Caroline Adkins, Allie N. Dick, Luke Millay, Vijay Subramaniam

Posters-at-the-Capitol

Morehead State University’s Derrickson Agricultural Complex (DAC) produces several agricultural enterprises and provides valuable hands-on experiences for students. Hay and corn are the two dominant crop enterprises which cover 58 percent of the total area. In addition, the DAC produces hay from six different farms using the crop-share leasing method. The primary objectives of this study are to (1) analyze the profitability of hay and corn production at the DAC and leased farms and (2) identify the strengths, and weaknesses of each farm to improve production efficiencies. Two years of data were collected, and the profitability of hay and corn …

Mobility Task Shows Rescue Of Scotopic Vision In A Swine Model For Autosomal Dominant Retinitis Pigmentosa After Treatment With The Meganuclease Rho 1-2, Gita Jaikumar, Jack Feist, Kautuk Kamboj, Aravind Kumar, Francesca Barone, Archana Jalligampala, Wei Wang, Jeff Smith, Dave Morris, Derek Jantz, Victor Bartsevich, Kristi Viles, Maureen Mccall

Posters-at-the-Capitol

Purpose : Retinitis pigmentosa (RP) is the most common form of inherited retinal disease with ~1:5000 people affected worldwide. The substitution of Proline to Histidine (P23H) at position 23 in the rhodopsin protein is the most common form of adRP in North America. We have shown that treating a transgenic P23H human RHO pig model of adRP (TgP23H hRHO) with a gene-editing meganuclease Rho 1-2, recovers rod structure and restores rod function. We ran WT, Rho1-2 treated and untreated TgP23H hRHO (Tg) pigs through an obstacle course to quantify visually guided mobility under light- and dark-adapted conditions using motion analysis …

A Byzantine-Period Monastery And Farmhouse In Nahal Pehar (Giv‘Ot Bar), In The Northern Negev, Nir-Shimshon Paran

'Atiqot

A Byzantine-period monastery and farmhouse were uncovered on the southwestern bank of Naḥal Peḥar, within the modern settlement of Giv‘ot Bar, in the northern Negev. The monastery was well-preserved, attesting to the daily life of the monks in the Negev in the Byzantine period. It was paved with poorly executed mosaic floors, probably laid by the monks themselves. Most of the finds in the monastery were uncovered on the floors, attesting to its orderly abandonment in the late Byzantine or beginning of the Umayyad period (sixth–seventh centuries CE). The monastery seems to have belonged to the widespread ecclesiastical system documented …

Intermediate Bronze Age Fauna From A Suspected Cultic Area At Nahal RefaʼIm, Liora Kolska Horwitz

'Atiqot

A small assemblage of faunal remains was recovered from four archaeological contexts excavated on the northern bank of Naḥal Refaʼim. These include Bronze Age rock-cut pits (Area 100), a structure (Area 300), a burial cave (Area 500) and an Ottoman-period shomera (Area 400). The remains represent almost exclusively domestic taxa—sheep, goat, cattle and donkey—some of which exhibit butchery marks, other modifications or burning. The faunal assemblage from the pits, together with other complementary data, may attest that the pits were used as favissae (cultic storage pits) associated with ritual activities at the site.

Intermediate Bronze Age, Middle Bronze Age Ii And Iron Age Ii Pottery From Nahal Refa’Im, Lilly Gershuny

'Atiqot

The pottery assemblage from the Naḥal Refa’im site originated in three different archaeological contexts: pits, structure(s) and a burial cave. These findings attest that the main period of occupation was during the Intermediate Bronze Age. One pit may have been reused for burial in Middle Bronze Age II, and the burial cave was visited in Iron Age II, possibly by the inhabitants of nearby Khirbat er-Ras.

Intermediate And Middle Bronze Age Settlement Remains, Domestic Worship, Pits And Burial Practices In Nahal RefaʼIm, Jerusalem, Shlomit Weksler-Bdolah, Alexander Onn

'Atiqot

Excavations on the northern bank of the Refa’im Valley uncovered four sites: a shaft tomb and building remains with a standing stone dating to the Intermediate Bronze Age; a concentration of eight pits dating to the Intermediate Bronze Age and the Middle Bronze Age II; and an Ottoman-period agricultural watchtower. The building remains and installations were probably part of the Intermediate Bronze Age settlement along Naḥal Refa’im. The standing stone’s prominent location, and the large concentration of pits and installations near it, may support its identification with domestic worship. The thin fill at the bottom of some of the pits …

Light-Microscopic And Spectroscopic Analyses Of The Skin Materials Used In The Tefillin And Mezuzah Slips From The Judean Desert, Yonatan Adler, Theresa Emmerich Kamper

'Atiqot

Among the Dead Sea Scrolls is an assemblage of ancient tefillin and mezuzah slips—ritual artifacts composed of thin animal skins inscribed with passages from the Pentateuch. This paper presents the results of light-microscopic and spectroscopic analyses conducted on 26 tefillin and 8 mezuzot from the Judean Desert caves. These analyses provide the first opportunity to identify the following characteristics on these artifacts: animal species; skin thickness; skin layers present; tannage; side/s of skin with writing. In time, these characteristics took on ritual significance, especially in later rabbinic halakhah. A significant finding is that the ancient tefillin analyzed here were all …

An Iron Age Iib–C Hebrew Stamp Seal With Apotropaic And Prophylactic Properties From The Southwestern Corner Of The Temple Mount, Jerusalem, Filip Vukosavović, Ronny Reich, Navot Rom, Yuval Baruch

'Atiqot

An Iron Age Hebrew iconic stamp seal was uncovered near the southwestern corner of the Temple Mount in Jerusalem. The seal, made of black stone, depicts a winged genie and a personal name, Yehoʽezer son of Hoshaʽyahu. This is the first depiction of the winged genie iconography in the region found in an archaeological excavation. Influenced by Neo-Assyrian art, the seal was created in Jerusalem by a local artist for Hoshaʽyahu, a member of the Judean elite, during the Assyrian Century. Later on, the seal was inherited by his son, Yehoʽezer. In addition to being used as a stamp, the …

Evidence Of Worship In The Rock-Cut Rooms On The Eastern Slope Of The City Of David, Jerusalem, Eli Shukron, Liora Freud, Helena Roth, Reli Avisar, Efrat Bocher

'Atiqot

This paper presents the finds retrieved from a unique series of rock-cut rooms found on the eastern slope of the City of David. These rock-cut rooms stand out in terms of their architectural features, as well as the artifacts discovered within them, all of which reflect on their function as a cultic complex, likely constructed in the Middle Bronze Age, with its final stage in Iron Age IIB. This complex offers profound evidence for the diversity of cultic practices in the capital of the Kingdom of Judah.

The Emergence Of Worship And Religion In The Neolithic Period: Direct And Indirect Evidence From Moẓa (Motza), Hamoudi Khalaily, Anna Eirikh-Rose, Ianir Milevski

'Atiqot

Evidence of worship and religion in the form of architectural remains is rather scanty before the shift in human behavior, from hunter-gatherers to sedentary communities, and the emergence of permanent settlements. Communal and ritual structures first appeared in the Natufian culture (12,500–9400 BCE) and expanded during the Neolithic period (9400–5300 BCE), alongside the treatment of burials linked to ritual related to ancestor worship. The excavations at Motza’s Final PPNB (7100–6700 BCE) layer exposed many non-residential structures, some presumably used for worship and ritual. Some burials, including the one interpreted here as a shaman burial, included objects of symbolic importance. Cultic …

Enhancing Student Creativity Through Online Learning: A Study Of Spada Indonesia In Civic Education Courses At Universitas Pendidikan Indonesia And Universitas Lambung Mangkurat, Dede Iswandi, Dasim Budimansyah, Kokom Komalasari, Susan Fitriasari

Jurnal Civics: Media Kajian Kewarganegaraan

This study examines the effectiveness of the SPADA Indonesia online learning platform in fostering creativity among students enrolled in Civic Education courses at Universitas Pendidikan Indonesia (UPI) and Universitas Lambung Mangkurat (ULM) Banjarmasin. Given the increasing importance of creativity as a critical skill for future graduates, this research aims to explore how the features and interactive elements of SPADA Indonesia contribute to enhancing student creativity within the context of mandatory Civic Education curricula. A total of 90 students participated in this study, comprising 45 from each university, selected through purposive sampling to ensure a diverse representation of experiences and perspectives. …

Chromosome 4 Duplication Associated With Strabismus Leads To Gene Expression Changes In Ipsc-Derived Cortical Neurons., Mayra Martinez-Sanchez, William C Skarnes, Ashish Jain, Sampath Vemula, Liang Sun, Shira Rockowitz, Mary C Whitman

Faculty Research 2025

BACKGROUND/OBJECTIVES: Strabismus is the most common ocular disorder of childhood. Three rare, recurrent genetic duplications have been associated with both esotropia and exotropia, but the mechanisms by which they contribute to strabismus are unknown. This work aims to investigate the mechanisms of the smallest of the three, a 23 kb duplication on chromosome 4 (hg38|4:25,554,985-25,578,843).

METHODS: Using CRISPR and bridging oligos, we introduced the duplication into the Kolf2.1J iPSC line. We differentiated the parent line and the line with the duplication into cortical neurons using a three-dimensional differentiation protocol, and performed bulk RNASeq on neural progenitors (day 14) and differentiated …

Beauty And Gore: Unsettling Audiences In The 2018 Production Of Ang Paglilitis Ni Mang Serapio, Sophia Martha B. Marco, Svetlana Antropova

Perspectives in the Arts and Humanities Asia

No abstract provided.

Beauty And Gore: Unsettling Audiences In The 2018 Production Of Ang Paglilitis Ni Mang Serapio, Sophia Martha B. Marco, Svetlana Antropova

Perspectives in the Arts and Humanities Asia

No abstract provided.

Review Of Notes On Bakya And Other Essays, Jose Monfred C. Sy

Perspectives in the Arts and Humanities Asia

No abstract provided.

Review Of Notes On Bakya And Other Essays, Jose Monfred C. Sy

Perspectives in the Arts and Humanities Asia

No abstract provided.

Is Modulation Of Immune Checkpoints On Glioblastoma-Infiltrating Myeloid Cells A Viable Therapeutic Strategy?, Ruochen Du, Jianzhong Zhang, Rimas V Lukas, Shashwat Tripathi, Jared T Ahrendsen, Michael A Curran, Crismita Dmello, Peng Zhang, Roger Stupp, Ganesh Rao, Amy B Heimberger

Faculty, Staff and Students Publications

The field of immunology has traditionally focused on immune checkpoint modulation of adaptive immune cells. However, many malignancies such as glioblastoma are mostly devoid of T cells and rather are enriched with immunosuppressive myeloid cells of the innate immune system. While some immune checkpoint targets are shared between adaptive and innate immunity, myeloid-specific checkpoints could also serve as potential therapeutics. To better understand the impact of immune checkpoint blockade on myeloid cells, we systematically summarize the current literature focusing on the direct immunological effects of PD-L1/PD-1, CD24/Siglec-10, collagen/LAIR-1, CX3CL1/CX3CR1, and CXCL10/CXCR3. By synthesizing the molecular mechanisms and the translational implications, …

А Review Of Scorpiofauna Of China: Nomenclatural Notes And Updated Faunistic Catalogue (Arachnida: Scorpiones), Victoria Tang

Euscorpius

Two genera associated with the Chinese scorpiofauna are reviewed, Razianus Farzanpay, 1987 and Reddyanus Vachon, 1972. Holotype female of Razianus xinjianganus Lourenço et al., 2010 is presumed to be lost, as well as all type material of other Chinese scorpions described before 2020. Comments are given on the species composition of genus Reddyanus with a new synonym: Isometrus (Reddyanus) tibetanus Lourenço & Zhu, 2008 = Reddyanus assamensis (Oates, 1888) syn. n. Reddyanus kanak Lourenço, 2023 is tentatively considered as a nomen dubium. An updated catalogue of Chinese scorpiofauna is provided, including their type locality and type depository, protonym, synonym(s), …

Changes In Vertical Stratification Of Neotropical Nymphalid Butterflies At Forest Edges Are Not Directly Caused By Light And Temperature Conditions, Brian K. Oye, Ryan I. Hill

Pacific Faculty Work

Habitat fragmentation and land use changes threaten neotropical habitats and alter patterns of diversity at forest edges. Like other arthropod assemblages, neotropical fruit-feeding butterfly communities show strong vertical stratification within forests, with some recent work showing its potential role in speciation. At forest edges, species considered to be forest canopy specialists have been observed descending to the forest understory, with the similarity in light conditions between the canopy and understory strata at edges hypothesized to be responsible for this phenomenon. We conducted a study using standardized sampling to document and quantify this edge effect, characterize edge and forest strata, and …

Pope Francis On Forced Migration: A Pastoral Of Mercy And Its Relevance In The Indonesian Context, Alexander Hendra Dwi Asmara, Martinus Dam Febrianto

Asia Pacific Mission Studies

Dealing with refugees, was the late Pope Francis’ legacy, during his pontificate, both as the leader of the Catholic Church and a global figure. This article reviews Francis’ pastoral approach of mercy, especially in his concern and advocacy for migrants and refugees, as expressed through his gestures, statements, thoughts, proposals, and policies. Along with issues of global inequality and ecological damage, Francis believed that forced migration can only be addressed through joint efforts based on recognizing human dignity, solidarity, the need for participation, as well as connectivity and inclusivity that encompasses the entire human family. This article then highlights the …

Dissecting The Binding Affinity Of Anti-Sars-Cov-2 Compounds To Human Transmembrane Protease, Serine 2: A Computational Study, Yue-Hui Shi, Jian-Xin Shen, Yan Tao, Yuan-Ling Xia, Zhi-Bi Zhang, Yun-Xin Fu, Ke-Qin Zhang, Shu-Qun Liu

Faculty, Staff and Student Publications

The human transmembrane protease, serine 2 (TMPRSS2), essential for SARS-CoV-2 entry, is a key antiviral target. Here, we computationally profiled the TMPRSS2-binding affinities of 15 antiviral compounds. Molecular dynamics (MD) simulations for the docked complexes revealed that three compounds exited the substrate-binding cavity (SBC), suggesting noncompetitive inhibition. Of the remaining compounds, five charged ones exhibited reduced binding stability due to competing electrostatic interactions and increased solvent exposure, while seven neutral compounds showed stronger binding affinity driven by van der Waals (vdW) interactions compensating for unfavorable electrostatic effects (including electrostatic interactions and desolvation penalties). Positive and negative hotspot residues were identified …

Tyrone Lee Dunn, Sr.

African American Funeral Programs

Tyrone Lee Dunn, Sr.pdf - Funeral program for Tyrone Lee Dunn