Digital Commons Network^™

An Efficient Phishing Detection Framework Based On Hybrid Machine Learning Models, Mohamed Elkholy, Mohamed Sabry, Hussam Elbehiery

Sustainable Machine Intelligence Journal

The paper discusses an improved phishing detection system that uses hybrid machine learning for analyzing URL-based features. Further improvement of prior work using better feature selection as well as ensemble methods is discussed. The proposed model enhances classification accuracy, precision, and recall by utilizing an innovative hybrid ensemble approach that integrates Logistic Regression, Support Vector Machine, and Decision Tree, alongside newly incorporated evaluation techniques. The results manifest high improvement in performance metrics as compared to the previous methods. Various comparisons and benchmarks with other methods have further proved the robustness of our proposed system for detecting malicious URLs.

Dataset For Binding Of Bl-Crystallin With Models Of Animal And Human Eye Lens-Lipid Membrane, Preston Hazen, Geraline Trossi-Torres, Nawal K. Khadka, Raju Timsina, Laxman Mainali

Biophysics Research Data

Several discoveries show that with age and cataract formation, B-crystallin binds with the lens membrane or associates with other lens proteins, which bind with the fiber cell plasma membrane, accompanied by light scattering and cataract formation. However, how lipids (phospholipids and sphingolipids) and cholesterol (Chol) influence B-crystallin binding to the membrane is unclear. This research aims to elucidate the role of lipids and Chol in the binding of B-crystallin to the membrane and the membrane’s physical properties (mobility, order, and hydrophobicity) with B-crystallin binding. We used electron paramagnetic resonance (EPR) spin-labeling methods to investigate the binding of BL-crystallin with a …

Atlantic Sharpnose Shark (Rhizoprionodon Terraenovae) Neurocranium, Michelle Bassali, David Kerstetter, Ema Nagel

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

Preparation , Structural Characterization And Antioxidant Activity Of Selenium Nanoparticles Decorated By Atrina Pectinata Polysaccharides, Zhang Yin, Nan Zhiguang, Lu Congfei, Wu Yuxin

Food and Machinery

［Objective］ This study aimed to optimize the preparation process of selenium nanoparticles stabilized by Atrina pectinata polysaccharides (APPS -SeNPs ),evaluate their antioxidant activity,and explore their potential as a functional food additive.［Methods］ Selenium nanoparticles were prepared using the sodium selenite reduction method with A.pectinata polysaccharides as stabilizer.The preparation process was optimized using single -factor experiments and response surface methodology (RSM ).The particle size,zeta potential and selenium content were measured,and the nanoscale structure was analyzed.Antioxidant activity was evaluated by assessing the scavenging effects on DPPH and hydroxyl (OH) radicals.Four factors influencing particle size -molar ratio of vitamin C to sodium selenite,reaction temperature,reaction …

Composition , Structure And Comparison Of In Vitro Hypoglycaemic And Hypolipidemic Activities Of Two Polysaccharides Extracted From Noni Fruit, Li Honghang, Wu Xiaoyong, Liang Jian, Wang Zhijiang

Food and Machinery

［Objective］ This paper aims to characterize the composition and structure of two polysaccharides extracted from Noni fruit and compare their in vitro hypoglycaemic and hypolipidemic activities.［Methods］ Two polysaccharides,NFP -30 and NFP -80,were extracted and isolated from Noni fruit by water extraction and ethanol precipitation method.They were then characterized by means of physicochemical analyses,spectral analyses,and scanning electron microscopy observations,and their in vitro hypoglycaemic and hypolipidemic activities were evaluated by the determination of the inhibition rates of α-glucosidase and pancreatic lipase.［Results］ The neutral sugar contents of NFP -30 and NFP -80 were (50.73±1.32)% and (42.30±1.11)%,respectively,and the glucuronic acid contents were (61.48±0.40)% and …

Preparation Process And Physicochemical Properties Of Tuna Dark Meat Protein Peptide, Sun Hui, Zhao Yongqiang, Yu Gang, Yang Tao, Xia Guanghua

Food and Machinery

［Objective］ To realize the high -value utilization of tuna by -products and prepare antioxidant peptides from them.［Methods］ Antioxidant protein peptides were prepared from the dark meat of yellowfin tuna by stepwise enzymatic hydrolysis using protease.The degree of hydrolysis and DPPH radical scavenging rate were used as evaluation indexes.The preparation process was optimized through one-way and response surface experiments,and the antioxidant activities,amino acid composition,and relative molecular mass distributions of the peptides were analyzed.［Results］ The optimal preparation process for the antioxidant peptides was enzymatic hydrolysis with flavor protease at 50 ℃,pH 7.00,enzyme concentration of 6 000 U/g,and digestion time of 4.00 h.In …

Effect Of Vacuum Pulsation Technology On Egg Pickling Efficiency And Quality, Zou Yanzi, Ju Haoyu, Geng Yahui, Liu Xinghan, Zhang Weipeng

Food and Machinery

［Objective］ To improve the efficiency and quality of salted egg pickling.［Methods］ Vacuum pulsation technology is applied to the pickling of eggs and compared with atmospheric pressure pickling (control group ).Vacuum -holding time,atmospheric pressure holding time,and pickling time are selected as the influencing factors,and the egg weight gain rate,egg white salt content,egg yolk salt content,egg yolk index,and egg yolk color of salted eggs during pickling are used as indicators for single factor experiments.［Results］ Under the conditions of a vacuum degree of -90 kPa and immersion in saturated salt water,with the pulsation ratio of vacuum -holding time to atmospheric pressure holding time …

Research Progress On Immunoassay Technology Based On Nanoenzyme Labeling In Detection Of Food Safety, Liu Ziyang, Hu Gaoshuang, Hao Jianxiong, Wang Chenyu, Shi Yingying, Yu Qingxiu

Food and Machinery

Food safety has become a hot topic of widespread concern across society,and efficient,sensitive detection technologies are essential tools for ensuring food safety.Immunoassay is the gold standard for high -sensitivity detection of biochemical targets,providing an excellent platform for the detection of food contaminants.In recent years,it has gradually been applied to various food safety detection methods.Nanoenzymes,as synthetic analogs of natural enzymes,offer advantages such as good stability and high sensitivity,meeting the demands of rapid detection methods under increasingly stringent detection limits.This article reviews the detection principles and advantages of immunoassay technology based on nanoenzyme labeling,discussing its applications in different areas of food safety …

Material Basis Differences And Production Process Consistency Rapid Screening Of Health Food Raw Material Aloe Vera, Zhao Zirui, Sa Yi, Zhao Chan, Zhou Xiaojuan, Zhang Mengling

Food and Machinery

［Objective］ To explore the effects of different production processes on the material basis of Aloe vera as a health food raw material,and to establish a rapid screening method for assessing production process consistency.［Methods］ Plant metabolomics technology,compound toxicity endpoint screening,and mass spectrometry were used to analyze the impact of different ethanol volume fractions on the material basis of A.vera.A method for rapid screening of A.vera production process consistency was established through production process categorization,differential chemical compound screening,and quantitative determination.Acute oral toxicity tests were conducted to assess the toxicity of typical A.vera extracts.［Results］ Compared with aqueous extraction,ethanol extraction significantly affected the main …

Quantification Of Eight Biogenic Amines In Aquatic Animal Products With Amino Acid Analyzer, Feng Hongyan, Xia Yongsheng, Qian Liangliang, Chen Xiaojuan, Zhou Jing

Food and Machinery

［Objective］ To address the cumbersome manual pre -column derivatization steps and poor derivative stability encountered in traditional chromatography when determining biogenic amines,so as to improve the efficiency and accuracy of detection.［Methods］ In this study,an amino acid analyzer method is established for the simultaneous determination of eight biogenic amines (i.e.,putrescine,histamine,cadaverine,spermidine,octopamine,spermine,tyramine,and phenylethylamine ) in aquatic animal products.The aquatic animal product samples are extracted using a sulfosalicylic acid solution,which is followed by high -speed refrigerated centrifugation,elution with potassium salt buffer,separation using a potassium ionic sulfonic acid based strong acid cation exchange chromatographic column,online derivatization with ninhydrin at 130 ℃,and detection at 570 nm.［Results］ …

Function Evaluation And Mechanism Of Ejiao Powder In Relieving Physical Fatigue, Han Xiang, Guo Xiaofei, Lu Xiaodong, Chen Xuemei, Hu Bo, Wang Zhouping

Food and Machinery

［Objective］ To investigate the active mechanism of Ejiao powder,prepared from donkey -hide gelatin,rock sugar,and rice wine,in alleviating physical fatigue in mice.［Methods］ Fifty specific pathogen -free (SPF) male BALB/c mice were randomly divided into five groups (10 in each group ):a blank negative control group,a model positive control group,and three experimental groups receiving low (0.67 g/kg ),medium (1.33 g/kg ),and high (2.67 g/kg ) doses of Ejiao powder.Except for the control group,all other groups were administered different doses of Ejiao powder via gavage for 30 consecutive days.Following administration,weight -bearing swimming time was recorded,and post -exercise serum urea,muscle glycogen,blood lactic acid,and ATP …

"I Know Who I Am": Draw-And-Tell Conversations With Gender-Creative Children, Eline Leemans Lenne

Dissertations and Theses

A growing number of children identify in various gender-creative ways, likely due to broader social awareness and affirmation of transgenderism. Gender-creative children face higher risks for adverse social, academic, mental health, and healthcare outcomes compared to non-transgender peers. Support from loved ones along with guidance from pediatric providers can mitigate poor outcomes and ensure that gender-creative children live healthy and happy lives. Young gender-creative children's perspectives about the aforementioned topics are markedly absent from the literature, which instead highlights adolescent and adult proxy perspectives.

In this participatory arts-based study anchored by a constructivist epistemology and informed by post-structuralist, queer, and …

Atlantic Sharpnose Shark (Rhizoprionodon Terraenovae) Jaw, Michelle Bassali, David Kerstetter, Ema Nagel

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

Saxophone Studio Recital: April 3, 2025, School Of Music,

School of Music Programs

Kemp Recital Hall

April 3, 2025

Thursday Evening

7:30 p.m.

Stoicism As A Panacea For Contemporary Problems, Taiwo Oriyomi Akande

LSU Master's Theses

The contemporary world is battling with the persistent problems of racism and environmental crises that threaten human co-existence and constitute an existential threat in general. These pressing issues have led to injustice, disunity, and ecological destruction. Though human history has recorded some victories in the advancement of human rights and environmental policies yet, there are still some forms of racism that are entrenched in society's structure. Environmental degradation also continues due to the failure or limitation in policies meant to tackle it, and the unsustainably bad attitudes of humans toward the environment. This thesis argues that Stoicism, a philosophical tradition …

“They Love Our Rhythm, But Not Our Blues:” An Examination Of The Relationship Between Hip Hop On Depression, Anxiety, And Self-Care Among African American And Hispanic/Latinx Emerging Adults, Richard W. Wiley Jr.

LSU Doctoral Dissertations

Depression and anxiety are among the most common mental health problems for emerging adults of color in higher education. Specifically, African American/Black and Hispanic/Latinx emerging adults on college campuses have poorer mental health than their White counterparts. Considering the systemic oppression and cultural stressors that impact mental health among African American/Black and Hispanic/Latinx students, Critical Race Theory (CRT) and Emerging Adulthood Theory were theoretical frameworks for this study. The purpose of this study was to examine the relationship between Hip Hop music and depression, anxiety, and intentional use as self-care among African American/Black and Hispanic/Latinx emerging adults who were college …

The Scowl - V. 88 N. 18 - April 3, 2025

The Cowl

The Cowl - student newspaper of Providence College. Vol. 88 No. 18 - April 3, 2025. 20 pages.

Determination Of Quinolones And Sulfonamides Residues In Aquatic Products And Livestock Products With Enhanced Matrix Removal-Lipid Adsorbent By Liquid Chromatography-Tandem Mass Spectrometry, Qin Yu, Xue Feng, Yu Junjie, Liu Yang, Gong Heng

Food and Machinery

［Objective］ To establish a new method for simultaneous detection of quinolones (QNs ) and sulfonamides (SAs) in aquatic products and livestock products.［Methods］ In pretreatment,this work compares the effect of extraction solvents on the recoveries and investigates the reduction or elimination effect of purification methods such as liquid -liquid extraction (n-hexane ),dispersive adsorption of the matrix (C18 and ethylenediamine -N-propyl silylated silica ),and general solid phase extraction (PRiME HLB ) on the matrix effect.The sample is pretreated by acetonitrile with 1.0% formic acid,purified by EMR -Lipid,and separated by ACQUITY UPLC®HSST3 column (3.5 µm,2.1 mm ×100 mm ) in 10 min.MS detection …

Applications Of Terahertz Spectroscopy In Food Industry, Ma Hao, Huang Luelue, Duan Xu, Li Xiaoting, Li Bin, Chen Xuan

Food and Machinery

The article summarizes the various application scenarios of terahertz spectroscopy technology in the food industry,analyzing its effectiveness,advantages,and disadvantages in different applications.In food traceability,this technology combines spectral and image signals to achieve precise predictions through mathematical models,effectively identifying issues such as food adulteration.In component detection,through qualitative and quantitative analyses,terahertz technology enables the detection of pesticide residues,veterinary drug residues,and food additives to ensure food safety.For quality monitoring,the technology can leverage spectral absorption characteristics and integrate them with mathematical models to monitor quality changes,such as oil oxidation and mold growth in agricultural products.

The Myth Of Second-Class Free Exercise, Frederick Mark Gedicks

Villanova Law Review (1956 - )

No abstract provided.

Phylogenetic Relationships And Species Delimitation Of Bunchgrass Lizards Of The Genus Sceloporus From Mexico With The Description Of A New Species, Tristan Charran, Jesús A. Loc-Barragan, Rafael Alejandro Calzada-Arciniega, Liz A. Alfaro-Juantorena, Raúl Cueva Del Castillo, Christopher Blair, Víctor H. Jiménez-Arcos

Publications and Research

Molecular data continue to serve as an invaluable tool to assess species limits and patterns of cryptic diversity, particularly in areas harboring high levels of biodiversity. The Sceloporus scalaris group, known as bunchgrass lizards, contains 13 described and one undescribed species distributed throughout high elevation biotas of Mexico. However, recent studies suggest that diversity in the group may be substantially underestimated. We collect new sequence data from four independent loci to determine the evolutionary distinctiveness and phylogenetic relationships of an isolated population of bunchgrass lizard in the Sierra San Juan (SSJ) in the Mexican state of Nayarit. Concatenation and coalescent-based …

The Effects Of Diluted Fungicide On Western Tiger Salamander (Ambystoma Mavortium) Health, Sage Veomett

Honors Program: Senior Projects (Public)

The Western Tiger Salamander (Ambystoma mavortium) is a species of salamander that is native to Nebraska. The Western Tiger Salamander population has been in decline, specifically in Southeast Nebraska (Ferraro, 2016). The purpose of this study was to determine whether low levels of Azoxystrobin fungicide deposited in the soil are harmful to the Western Tiger Salamander. In this study, soil in tanks containing pairs of Western Tiger Salamanders was treated with levels of Azoxystrobin 0.5x under the recommended label amount for usage. Fifteen salamanders in total were used. Four tanks of salamander pairs were treated with the Azoxystrobin …

Dissecting The Contribution Of Stmn2 To Als Pathogenesis, Kelsey Krus

Arts & Sciences Graduate Student Theses and Dissertations

TDP-43 is required for splicing of Stathmin-2 (STMN2) transcript, so STMN2 is reduced in most ALS patients. TDP-43 does not regulate STMN2 in mice as it does in humans. Thus, mouse models of ALS do not reflect patient loss of STMN2. To test the hypothesis that a reduction in STMN2 contributes to ALS pathogenesis, we generated STMN2 knockout mice. Constitutive STMN2 loss induces an early sensory and motor neuropathy with disrupted motor behavior and dramatic distal neuromuscular junction (NMJ) denervation. This NMJ pathology occurs in fast-fatigable motor units, which are the most vulnerable in ALS. In contrast, motoneurons and axons …

April 3, 2025, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Computed Microtomographic Imaging Of Revascularization During Healing Of Achilles Tendon Injury, Seher Yilmaz, Ozan Akkus

Faculty Scholarship

Angiogenesis in injured tendons may contribute to regeneration, but quantifying it post-injury has been mostly limited to 2D semi-quantitative histology. This study aimed to develop micro-CT as a 3D tool to quantitatively assess tendon blood vessels in an experimental animal model. Adult male Wistar rats (N = 36) had injuries induced in their Achilles tendons by needle insertion. The study included three post-injury groups: 12 hours post-injury (12H), 3 weeks post-injury (3W), and 8 weeks post-injury (8W). The uninjured left Achilles tendon served as the control for each group. Intravital cardiac perfusion with barium sulfate enhanced contrast between tendon and …

Breaking The Synaptic Vesicle Cycle: Mechanistic Insights Into Presynaptic Dysfunctions In Epilepsy, Kevin Jiang, Lu-Tang Yang, Mingshan Xue

Duncan NRI Faculty and Staff Publications

Synaptic dysfunction is a hallmark of many neurological disorders including epilepsy. An increasing number of epilepsy-causing pathogenic variants are being identified in genes encoding presynaptic proteins that affect every step of the synaptic vesicle cycle, from vesicle loading, tethering, docking, priming, calcium sensing, fusing, to recycling. These different molecular dysfunctions result in converging impairment of presynaptic neurotransmitter release, yet lead to diverse epileptic disorders. This review focuses on representative monogenic epileptic disorders caused by pathogenic variants of key presynaptic proteins involved in different stages of the synaptic vesicle cycle: SYN1 (vesicle pool regulation), STXBP1 (vesicle docking, priming, and fusion), and …

De Novo Variants In Cdkl1 And Cdkl2 Are Associated With Neurodevelopmental Symptoms, Ali H Bereshneh, Jonathan C Andrews, Daniel F Eberl, Guney Bademci, Nicholas A Borja, Stephanie Bivona, Wendy K Chung, Shinya Yamamoto, Michael F Wangler, Shane Mckee, Mustafa Tekin, Hugo J Bellen, Oguz Kanca

Duncan NRI Faculty and Staff Publications

The CDKL (cyclin-dependent kinase-like) family consists of five members in humans, CDKL1-5, that encode serine-threonine kinases. The only member that has been associated with a Mendelian disorder is CDKL5, and variants in CDKL5 cause developmental and epileptic encephalopathy type 2 (DEE2). Here, we study four de novo variants in CDKL2 identified in five individuals, including three unrelated probands and monozygotic twins. These individuals present with overlapping symptoms, including global developmental delay, intellectual disability, childhood-onset epilepsy, dyspraxia, and speech deficits. We also identified two individuals with de novo missense variants in CDKL1 in the published Deciphering Developmental Disorders (DDD) and GeneDx …

Nitrous Oxide Activates Layer 5 Prefrontal Neurons Via Sk2 Channel Inhibition For Antidepressant Effect, Joseph Cichon, Thomas T Joseph, Xinguo Lu, Andrzej Z Wasilczuk, Max B Kelz, Steven J Mennerick, Charles F Zorumski, Peter Nagele

2020-Current year OA Pubs

Nitrous oxide (N

Exit Strategy: How Methods Of Gaining Independence From European Colonial Powers Impact Development In Post-Colonial African Nations, Sophia Wehle

Undergraduate Student Symposium

How does the way a colony gains independence from its power impact that colony’s future development? It is well documented that being a former colony has an impact on how a nation develops once they are independent, however, what is not clear is if a nation’s development is impacted by the way they separate from their colonial power. This paper argues that there is a correlation between the way a colony gains their independence and how developed they are. For the sake of this research three main ways of gaining independence will be considered: though violent resistance, peaceful negotiations, or …

Comparative Genomics Across Streptomyces Murinus Strains To Identify Biosynthetic Gene Cluster For Antifungal Metabolite 'Pentamycin', Nitish Dundigalla, Ashley Bran Sampson, Smrithi Mukund, Melianni Terrero Terrero

Undergraduate Student Symposium

Streptomyces are filamentous, Gram-positive bacteria in the phylum Actinobacteria that are known to produce a diverse array of antimicrobial metabolites. A Streptomyces murinus strain SPC1, contains a 15- gene biosynthetic gene cluster (BGC) that produces an antifungal metabolite ‘pentamycin’ (fungichromin), and is shown to exhibit antimicrobial activity against fungal pathogens of palms¹. Using SPC1 strain as a reference, we analyzed the conservation of BGCs across 17 other S. murinus strains. A specialized bioinformatics analysis tool, antiSMASH² , was used to identify and annotate BGCs that produce pentamycin. Pairwise comparison of the 15 genes comprising the pentamycin cluster …