Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 25561 - 25590 of 732890

Full-Text Articles in Entire DC Network

Rnai Pathway Homeostasis Is Essential For Longevity In C. Elegans., Sejal Dulal May 2025

Rnai Pathway Homeostasis Is Essential For Longevity In C. Elegans., Sejal Dulal

2025 Spring Honors Capstone Projects - Archive

RNA interference (RNAi) is a gene regulatory mechanism that is conserved across all animal species, including humans and the microscopic nematode, Caenorhabditis elegans. Many studies have identified the RNAi pathway factors and dissected the regulatory mechanisms of RNAi pathways, but there is little understanding of how the RNAi pathways themselves are regulated. Previously, Rogers and Phillips identified a feedback loop mediated by a pair of small RNA sensors, Sensor of siRNAs-1 (sosi-1) and eri-6[e-f], embedded within the genomic locus of a small RNA biogenesis factor, ERI-6/7. In this feedback motif, loss of small RNA-mediated silencing of …

Go to article

Cuegen: Customizing Sensor Captions For Neon Bending Tutorials, Gunnika Kapoor May 2025

Cuegen: Customizing Sensor Captions For Neon Bending Tutorials, Gunnika Kapoor

2025 Spring Honors Capstone Projects - Archive

Methods of knowledge transfer that rely primarily on visual and/or auditory formats do not effectively convey context-specific or implicit skills, known as tacit skills. This limits knowledge transfer. In this work, the use of customizable pitch captions and spatial audio vibration captions is proposed to aid in conveying this tacit knowledge for neon glass bending video tutorials. Such a system is designed to provide users with greater control and support, which may maximize the information they obtain from, improve the autonomy they have with, and experience they have with a learning tool. As such, a system interface was developed that …

Go to article

Elucidating The Role Of Transposable Element Derived Gene, Dplg3, In Drosophila Melanogaster, Kaisy A. Martinez May 2025

Elucidating The Role Of Transposable Element Derived Gene, Dplg3, In Drosophila Melanogaster, Kaisy A. Martinez

2025 Spring Honors Capstone Projects - Archive

A big fraction of most eukaryotic genomes is comprised of transposable elements (TEs). TEs are mobile genetic sequences often causing deleterious effects as they increase in copy number. On rare occasions, TEs can undergo molecular domestication, where the TE proteins are co-opted by the host to serve cellular functions. In Drosophila melanogaster, domestication from PIF/Harbinger TEs has resulted in five Drosophila PIF-Like Genes (DPLG1-4 and 8). This study focuses on investigating the function of DPLG3. In DPLG3 knock out lines, DPLG3-KO, a fraction of the progeny shows an abnormal gonad phenotype. We sought to confirm …

Go to article

Wild West Healthcare: Addressing Healthcare Disparities In Rural Texas, Alexis K. O'Neal May 2025

Wild West Healthcare: Addressing Healthcare Disparities In Rural Texas, Alexis K. O'Neal

2025 Spring Honors Capstone Projects - Archive

Rural communities in Texas face significant barriers to healthcare access, including geographic isolation, limited healthcare facilities, and shortages of healthcare providers, which exacerbate health disparities and contribute to poorer health outcomes (Bennett et al., 2019; Jafri et al., 2024). This study examines healthcare access disparities between rural and urban areas in Texas, focusing on the role of telehealth and its impact on vulnerable populations, such as older adults and cardiovascular patients. Regions of Texas were categorized into rural, metropolitan, and metroplex areas to analyze variations in healthcare outcomes and access. Rural areas, defined as those with populations under 200,000, struggle …

Go to article

Assessing The Prevalence Of Ehrlichia Spp. In Ticks Associated With Canids In Arkansas, Eva J. Berryhill May 2025

Assessing The Prevalence Of Ehrlichia Spp. In Ticks Associated With Canids In Arkansas, Eva J. Berryhill

Animal Science Undergraduate Honors Theses

Canine ehrlichiosis is a disease that is commonly seen in dogs. In previous studies, the southeastern part of the United States has been identified as an area of high prevalence. Arkansas was included in the region where the prevalence is high. Changes in climate, household income, and tick population were identified as factors contributing to this high prevalence. Canine ehrlichiosis is caused by three Ehrlichia spp., which are E. canis, E. ewingii, and E. chaffeensis. Ticks are responsible for transmitting the disease, specifically R. sanguineus, D. variabilis, and A. americanum. For this study, the goal was to determine the prevalence …

Go to article

Utilizing 16s Ribosomal Rna Sequencing To Identify Bacterial Species Colonizing Lame Birds With Bacterial Chondronecrosis With Osteomyelitis, Kara Hoover May 2025

Utilizing 16s Ribosomal Rna Sequencing To Identify Bacterial Species Colonizing Lame Birds With Bacterial Chondronecrosis With Osteomyelitis, Kara Hoover

Animal Science Undergraduate Honors Theses

Broiler chicken lameness has become prevalent in recent years due to high growth rates in broilerchickens. Bacterial chondronecrosis with osteomyelitis (BCO), the main cause of lameness, is characterized by necrosis of femoral and tibial heads in affected birds. Heavier birds are more susceptible to mechanical stress in these regions, which results in microfractures, leading to lameness. BCO lameness poses huge financial pressure to the poultry industry, as 14-50% of flocks can become affected during outbreaks. The purpose of this experiment was to identify bacterial species present in birds with BCO lameness. A total of 1,560 chicks were randomly distributed into …

Go to article

The Effect Of 1,25-Dihydroxyvitamin D3 Supplementation On Humoral Immunity Against Bacterial Chondronecrosis With Osteomyelitis Lameness In Broiler Chickens, Bailey Herberger May 2025

The Effect Of 1,25-Dihydroxyvitamin D3 Supplementation On Humoral Immunity Against Bacterial Chondronecrosis With Osteomyelitis Lameness In Broiler Chickens, Bailey Herberger

Animal Science Undergraduate Honors Theses

Bacterial chondronecrosis with osteomyelitis (BCO) lameness, the most predominant locomotive illness in fast-growing broilers, causes substantial animal well-being issues and affects broiler production, leading to huge financial losses. Several strategies, including feed supplementations using organic trace minerals, vitamin D, probiotics, and prebiotics, have been utilized to alleviate BCO lameness incidences in broiler chickens. Previous studies have indicated that feeding an additive of Panbonis®-G-1,25(OH)2D3 from Solanum glaucophyllum containing 1 µg/kg G-1,25(OH)2D3 to broilers for the first 28 days of their production cycle reduced BCO lameness by more than 50%. In this study, we …

Go to article

Investigations Of Musical Constructs: An Analysis Of Graphic Scores And Their Spatial Relationships, Garrett J. Henderson May 2025

Investigations Of Musical Constructs: An Analysis Of Graphic Scores And Their Spatial Relationships, Garrett J. Henderson

2025 Spring Honors Capstone Projects - Archive

This project seeks to understand, through creative production, how graphic scores and their purpose as a medium can be applied to architectural design. Graphic scores are an abstract representation of musical notation; they utilize unfamiliar concepts and shapes to illustrate musical ideas through unconventional means. Discovering how one can reverse-engineer these works of notation can allow architectural designers to rethink the representation of spaces and the underlying inspirations that form them. Research into broader artistic overlap, historical context, and precedent analysis culminated into a set of drawings that illustrate such concepts through an architectural lens. The production of these drawings …

Go to article

Uncovering The Evolutionary Origins Of Neo-Sex Chromosomes In The Insect Family Membracidae, Mary Kumah May 2025

Uncovering The Evolutionary Origins Of Neo-Sex Chromosomes In The Insect Family Membracidae, Mary Kumah

2025 Spring Honors Capstone Projects - Archive

This research explores the evolution of the neo-XX/XY sex chromosome system of Amblyophallus exaltatus, a treehopper insect in the family Membracidae. Neo-XX/XY sex chromosome systems can evolve from an XX/X0 sex chromosome system via fusion events between the X chromosome and an autosome. Although cytological work has indicated the presence of a neo-XX/XY system within A.exaltatus, the chromosomal identity of the fused autosome and the molecular drivers behind this chromosomal fusion remain poorly understood. By performing a coverage analysis with whole genome sequence data, the parts of the A.exaltatus genome that fused with the X chromosome will be better …

Go to article

Why You're Gayhee For Jaehee: How Dating Sims Promote Queer Self-Discovery, Amira Elliby May 2025

Why You're Gayhee For Jaehee: How Dating Sims Promote Queer Self-Discovery, Amira Elliby

2025 Spring Honors Capstone Projects - Archive

Dating simulators are a video game sub-genre in which the player’s primary goal is to romantically pursue their favorite love interest through in-game interactions. While some dating sims present situations that encourage heterosexual female players to question, explore, and even accept possible queer identities for themselves, there is little research on what specific game elements foster this exploratory behavior. This project examines player responses and in-game content from two dating sims, Chrono Days Sim Date and Mystic Messenger, to determine which game aspects women found most helpful in encouraging them to question their own sexualities. Out of five key …

Go to article

Love Drugs: Exploring The Ethical Implications Of Relationship Targeting Biochemical Supplements, Hallie Young May 2025

Love Drugs: Exploring The Ethical Implications Of Relationship Targeting Biochemical Supplements, Hallie Young

2025 Spring Honors Capstone Projects - Archive

"Love drugs" can be defined as chemical interventions that affect desire, attraction, and affection. Contemporary advancements in neurochemical interventions have increased interest in love drugs and highlighted the need for accessible love drug analyses. This project explores how love drugs will affect contemporary relationships through realistic literary scenarios informed by current philosophical literature. These scenarios consist of three vignettes compiled into a novella-length creative work. It was initially anticipated that these vignettes would reveal that introducing a meta-biological or chemical intervention into social situations where authenticity is normatively highly valued would prompt participant introspection. In practice, this work finds that …

Go to article

Encanto The Musical: An Exploration Of Translating Media From Film To Stage, Isabel Perez-Flores May 2025

Encanto The Musical: An Exploration Of Translating Media From Film To Stage, Isabel Perez-Flores

Whittier Scholars Program

I’m going to be honest: I did not go into this project with the intent of radically changing Encanto. I had some points I wanted to expand upon, some improvements and edits that I felt the film could have utilized, but overall, I was satisfied with the way the story was told. The real change, I’ve come to realize, lies not in the story and the script itself, but in the way the story is told. The obvious change is that this version of Encanto, in an ideal world, would be performed in front of a live audience, in a …

Go to article

Triple-Valued Neutrosophic Set, Quadruple-Valued Neutrosophic Set, Quintuple-Valued Neutrosophic Set, And Double-Valued Indetermsoft Set, Takaaki Fujita May 2025

Triple-Valued Neutrosophic Set, Quadruple-Valued Neutrosophic Set, Quintuple-Valued Neutrosophic Set, And Double-Valued Indetermsoft Set, Takaaki Fujita

Neutrosophic Systems with Applications

Concepts such as Fuzzy Sets, Neutrosophic Sets, Rough Sets, and Plithogenic Sets have been extensively studied to address uncertainty, finding diverse applications across various fields. A Double-Valued Neutrosophic Set (DVNS) extends traditional neutrosophic sets by introducing two distinct indeterminacy components: one leaning towards truth and the other towards falsity. In this paper, we explore Triple-Valued Neutrosophic Sets, Quadruple-Valued Neutrosophic Sets, and Quintuple-Valued Neutrosophic Sets, as well as an extension of the Indetermsoft Set, termed the Double-Valued Indetermsoft Set. Note that related concepts such as the Multi-Valued Neutrosophic Set and the n-Valued Refined Neutrosophic Set have already been established.

Go to article

First Specimen-Based Record Of Barbonymus Schwanefeldii (Bleeker, 1854) (Teleostei: Cyprinidae) From Laguna De Bay, Philippines, Kent Elson S. Sorgon, Marjorie Juliana L. Martinez, Andrei Justin F. So, Mariko Franccesca R. Aboganda, Jazreen Nicole G. Parungo, Aeris Johanne G. Poricallan, Keona Tiffany B. Prieto, Mellissa Jewel S. Magday, Alexa Charlize Dc Geronimo, Ma. Vianca Julia E. Anupol, Derreck O. De Leon May 2025

First Specimen-Based Record Of Barbonymus Schwanefeldii (Bleeker, 1854) (Teleostei: Cyprinidae) From Laguna De Bay, Philippines, Kent Elson S. Sorgon, Marjorie Juliana L. Martinez, Andrei Justin F. So, Mariko Franccesca R. Aboganda, Jazreen Nicole G. Parungo, Aeris Johanne G. Poricallan, Keona Tiffany B. Prieto, Mellissa Jewel S. Magday, Alexa Charlize Dc Geronimo, Ma. Vianca Julia E. Anupol, Derreck O. De Leon

Biology Faculty Publications

The introduction of non-native fish species in the freshwater ecosystems of the Philippines presents a clear threat to native ichthyofauna, making verified reports of such introductions all the more critical. Through the examination of a collected specimen and anecdotes from fisherfolk and social media, we present here the first records of the occurrence of the tinfoil barb, Barbonymus schwanefeldii (Bleeker, 1854), in Laguna de Bay, Luzon Island, Philippines. This represents the addition of another non-native fish species in this lake, which is increasingly becoming dominated by non-native and invasive fishes that have been intentionally or accidentally introduced. Monitoring landed fish …

Go to article

Tracing Clovis Landscapes: Chert Sourcing At The Copelin Valley Site In Kentucky., Shaylee Scott May 2025

Tracing Clovis Landscapes: Chert Sourcing At The Copelin Valley Site In Kentucky., Shaylee Scott

Electronic Theses and Dissertations

This study conducts a raw material sourcing analysis of Clovis lithic artifacts from Copelin Valley, Hart County, Kentucky, a key Clovis occupation site. Over a decade of documenting private collections and recent archaeological investigations confirm the site's significance within the Paleoindian landscape. Using reflectance spectroscopy, a non-destructive technique, this research assesses chert source probabilities for over 100 Clovis points and tools. By integrating spectral data with geological sourcing frameworks, this study examines raw material procurement strategies and their implications for Clovis mobility and settlement. The findings reveal patterns in material selection, shedding light on occupation intensity, technological organization, and landscape …

Go to article

Advancing Research On Retinitis Pigmentosa: An Investigation Of Natural History, Visual System Plasticity, And Mutation-Independent Treatment., Cecilia A. Attaway May 2025

Advancing Research On Retinitis Pigmentosa: An Investigation Of Natural History, Visual System Plasticity, And Mutation-Independent Treatment., Cecilia A. Attaway

Electronic Theses and Dissertations

Retinitis Pigmentosa (RP) is an inherited retinal disease characterized by rod and then cone photoreceptor degeneration. ~25% of cases are caused by a genetic mutation that results in autosomal dominant RP (adRP). There has been a lack of exploration of the progression of degeneration in adRP models. In Chapter Two, I examined visual acuity (VA) changes, retinal structure, and function from early to late-stage disease in a murine P23H Rho ‘knock-in’ mouse model (RhoP23H/+), the most common form of adRP in North America. To establish a natural history, I evaluated behavioral VA, using the visual water task, …

Go to article

“Souls Cannot Rest In Contested Places”: An Ethnographic Case Study And Archeological Environmental Assessment Of The North Shore Cemeteries., Henrietta K. Ransdell May 2025

“Souls Cannot Rest In Contested Places”: An Ethnographic Case Study And Archeological Environmental Assessment Of The North Shore Cemeteries., Henrietta K. Ransdell

Electronic Theses and Dissertations

This thesis is an ethnographic case study and archeological-environmental assessment of the North Shore Cemeteries to derive condition commentary and care recommendations for the landscape, cultural resources, descendant community, and Great Smoky Mountains National Park. Framed by theories of space-place culture, dispossession, and public lands co-management, this multi-methods, interdisciplinary thesis combines historical context, environmental conditions, archeological documentation, participant observations, and ethnographic interviewing of NPS and community affiliates to derive applied strategies for cemetery repair, operational efficacy, and this specific, public lands “co-management” relationship. With data from 12 interviews, eight participant observations, and six condition assessment surveys, it’s argued that perceptions …

Go to article

Affective Teacher Tok: A Sociomaterial Analysis Of Teachers’ Digital Literacy Practices On Social Media., Jessica Nicole Gottbrath May 2025

Affective Teacher Tok: A Sociomaterial Analysis Of Teachers’ Digital Literacy Practices On Social Media., Jessica Nicole Gottbrath

Electronic Theses and Dissertations

Mass media often depicts teachers in oversimplified terms, as heroic saviors or dangerous agents of indoctrination, flattening the complex realities of their daily work and lived experiences. This polarization contributes to the ongoing deprofessionalization of teaching, where educators’ expertise is increasingly questioned and politicized. In response to these reductive portrayals and the everyday pressures of the profession, some teachers have turned to short-form social media videos as a creative outlet to share personal and professional insights. To explore how teachers reclaim agency through their digital literacy practices, this study employs mixed-methods research to investigate how educators use networked microvideos to …

Go to article

The Ten Commandments Goes Hollywood: A Century's Film Adaptations Of The Moses Narrative As Reflections Of American Culture., Aaron Nusz May 2025

The Ten Commandments Goes Hollywood: A Century's Film Adaptations Of The Moses Narrative As Reflections Of American Culture., Aaron Nusz

Electronic Theses and Dissertations

This dissertation examines the various film adaptions that the American Hollywood has released about the Biblical character Moses. The scope of this examination is limited to theatrical releases from Hollywood in English, which spans roughly 100 years of history. Each of the five films examined in this dissertation represents a different period in American culture, and all are from a different film genre. Starting with The Ten Commandments (1923) which represents the silent-film era of Hollywood, to the 2014 blockbuster Exodus: Gods and Kings, the film industry has continued to produced films which examine the life and deeds of Moses …

Go to article

Black Women Under The White Gaze: Resistance From Enslavement To Incarceration And Reentry., Barbie C. Parker May 2025

Black Women Under The White Gaze: Resistance From Enslavement To Incarceration And Reentry., Barbie C. Parker

Electronic Theses and Dissertations

Black women in the United States who are currently incarcerated or have previously served time in prison have a particular need for protection as they move through the criminal “injustice” system because they frequently act as the primary caregivers for their families. Consequently, Black female convicts have historically had to create their social networks inside and outside carceral spaces as a form of resistance to white supremacist ideologies and as a site of protection. By highlighting Black women’s history of enslavement and incarceration, the different forms of resistance, and centering their narratives, we can paint a more complex picture of …

Go to article

The Effects Of Ethanol And Tributyrin On Alzheimer's Disease Pathogenesis In 3×Tg-Ad Mice., Lucy June Sloan May 2025

The Effects Of Ethanol And Tributyrin On Alzheimer's Disease Pathogenesis In 3×Tg-Ad Mice., Lucy June Sloan

Electronic Theses and Dissertations

Alzheimer’s disease (AD) is a complex progressive neurodegenerative dementia with clinical hallmarks of amyloid-β plaques, hyper-phosphorylated tau in neurofibrillary tangles (NFTs), and neurodegeneration. Chronic, excessive alcohol consumption is associated with an increased risk for developing AD and other dementias. Both AD and chronic alcohol consumption are associated with dysbiosis in the gut microbiome (GM) characterized by a significant loss of beneficial butyrate-producing bacteria within the Firmicutes phylum. Previous studies demonstrate that chronic alcohol consumption accelerates AD pathogenesis in the 3×Tg-AD mouse model and that oral tributyrin (TB) supplementation in 3×Tg-AD mice reduces age-associated GM dysbiosis and AD-associated neurobehavioral deficits and …

Go to article

Necessitating Autonomy: Performing Black Womanhood., Krystal Chavonne Waller May 2025

Necessitating Autonomy: Performing Black Womanhood., Krystal Chavonne Waller

Electronic Theses and Dissertations

This thesis examines the ways in which Black womanhood should autonomously be represented on the stage and/or the screen. By defining the theories of Black Feminist Thought, Black Performance, Trap Feminism and Sankofa, I create a praxis that provides Black femme performers with tools for authentic characterization. By acknowledging and respecting that Black women are not monolithic, this thesis also explores the evolution of theatrical representations of Black Womanhood—particularly U.S. Black womanhood from the late 19th century to modern day. Using historical narrative, analysis, acting techniques learned during my MFA program, and personal reflection, I advocate for Black women …

Go to article

Applying Residence Time Distribution Theory To Coronary Thermodilution Curves., Jacob Michael Miller May 2025

Applying Residence Time Distribution Theory To Coronary Thermodilution Curves., Jacob Michael Miller

Electronic Theses and Dissertations

Cardiovascular diseases remain the leading cause of death worldwide and coronary microvascular dysfunction is one cardiovascular disease which is particularly challenging to diagnose and treat. Coronary thermodilution is a widely used, invasive procedure to evaluate microvascular function by generating physiological indices such as coronary flow reserve and the index of microvascular resistance. Although commonly cited as an indicator dilution method in the cardiovascular literature, current coronary thermodilution techniques lack rigorous application of the accompanying mathematical framework, thereby leaving potentially valuable diagnostic information unexploited. This study bridges that gap by demonstrating the equivalence between indicator-dilution theory and residence time distribution theory …

Go to article

Long-Term Changes In Bolus Parameters During Swallowing Post-Chemoradiation Treatment., Brittany Rebecca Smiley May 2025

Long-Term Changes In Bolus Parameters During Swallowing Post-Chemoradiation Treatment., Brittany Rebecca Smiley

Electronic Theses and Dissertations

Current treatment for oropharyngeal cancer involves chemoradiation, which can have profound effects on swallowing function. Submental muscle activity is critical for airway protection and bolus transit but is highly susceptible to radiation-related swallowing impairments. This study examined whether chemoradiation targeting the submental muscles leads to measurable changes in esophageal distension during swallowing in a rodent model. We hypothesized that rats receiving chemoradiation would exhibit aberrant esophageal distension compared to chemotherapy-only controls. Twenty male rats underwent four cycles of cisplatin concurrently with either radiation or sham radiation. High-speed videofluoroscopy swallow studies were conducted pre- and post-treatment with thin liquids to analyze …

Go to article

Black Childhood In Focus: Counter-Histories Of Black Urban Childhood In Preserve The Baltimore Uprising, A 21st Century Digital Participatory Archive., Ameena Basheera X Ruffin May 2025

Black Childhood In Focus: Counter-Histories Of Black Urban Childhood In Preserve The Baltimore Uprising, A 21st Century Digital Participatory Archive., Ameena Basheera X Ruffin

Electronic Theses and Dissertations

This study examines the (mis)representation of Black urban childhood in the United States and proposes a framework for Black children’s inclusion in historical narratives. Black children have been excluded from constructs of childhood innocence, justifying violence against Black children and perpetuating anti-Black social hierarchies. This study builds on the work of Saidiya Hartman, advocating for a critical approach to studying, archiving, and understanding Black childhood through the lenses of region, race, age, and gender. Using the participatory digital archive Preserve the Baltimore Uprising as a case study, the research explores Black children’s presence and contributions during the 2015 Baltimore Uprising. …

Go to article

A Black Sherlock Holmes: An Exploration Of Nonconforming Characterization., Faith Janaye Artis May 2025

A Black Sherlock Holmes: An Exploration Of Nonconforming Characterization., Faith Janaye Artis

Electronic Theses and Dissertations

In the wake of diversity initiatives in the greater American theatre landscape, we are now including more Black actors than ever. Whether that be through the inclusion of diverse playwrights or implementing new casting protocols, we now have Black people in the room. However, when portraying the Black “version” of a character (i.e. Black Annie, Black Ariel, Black Juliet) a question still plagues the Black Actor’s mind: how am I meant to fit here? I evaluate my process of portraying Sherlock Holmes as my thesis role. By challenging the implied white perspective in this “universal” story (despite its feminist retelling), …

Go to article

Cns-Specific Hiv Reservoir Characterization In Humans: Advancing Our Understanding Through Novel Genomics Methods., Ghazal Sadri May 2025

Cns-Specific Hiv Reservoir Characterization In Humans: Advancing Our Understanding Through Novel Genomics Methods., Ghazal Sadri

Electronic Theses and Dissertations

The persistence of the human immunodeficiency virus (HIV) reservoir despite years of suppressive antiretroviral therapy (ART) represents the principal obstacle to achieving a functional cure. Because the intact, replication-competent portion of the reservoir drives viral rebound after treatment interruption, HIV cure strategies must specifically identify and target cells harboring these proviruses. Conventional reservoir‐characterization techniques typically require separate assays to capture integration sites, assess proviral integrity, and quantify clonal proliferation and they rely on short‐read sequencing. These limitations hinder our ability to understand how integration landscapes, the integrity of the HIV genome, and cell‐division dynamics intersect to maintain viral persistence in …

Go to article

Untitled: Study., Annabela Cockrell May 2025

Untitled: Study., Annabela Cockrell

Electronic Theses and Dissertations

Untitled: Study is an exploration into “The Work”, which is a constant evolution of the idea of the same piece. Every new work is an evolution of the one before. Previous works are often reworked and self-cannibalized into the next generation. The Work will never be presented the same way twice. There is a temporality in making and installing the work this way, what with the form, the space, the ness of it never being the same. All the while conflicting by being viewed as being the same in the same breath.

Go to article

Mechanisms Of Particulate Hexavalent Chromium-Induced Inhibition Of Homologous Recombination Repair: Targeting The Bcdx2 Complex Considered Through A One Health Perspective., Aggie W. Brownell May 2025

Mechanisms Of Particulate Hexavalent Chromium-Induced Inhibition Of Homologous Recombination Repair: Targeting The Bcdx2 Complex Considered Through A One Health Perspective., Aggie W. Brownell

Electronic Theses and Dissertations

Lung cancer remains the leading cause of cancer death, often linked to smoking. However, smoking alone does not account for all cases. Exposure to environmental metals like hexavalent chromium [Cr(VI)] also contributes to lung cancer. Cr(VI) causes lung cancer by inducing chromosome instability (CIN), an early hallmark of its carcinogenic mechanism. While it has been established that Cr(VI) induces chromosome instability, the precise mechanisms underlying the chromosome instability are poorly understood. This dissertation investigates the mechanisms of carcinogenesis associated with zinc chromate, a particularly potent particulate form of hexavalent chromium. Studies show Cr(VI) induces DNA double-strand breaks and impairs the …

Go to article

A First-Generation 4-H Youth Member Intervention Framework To Support Members To Enter, Engage, And Persist In The Program, Jeremy Elliott-Engel, Nicholas A. A Morris May 2025

A First-Generation 4-H Youth Member Intervention Framework To Support Members To Enter, Engage, And Persist In The Program, Jeremy Elliott-Engel, Nicholas A. A Morris

Journal of Youth Development

The First-Generation 4-H Youth Member (FG4-HYM) Intervention Framework is an organizational management perspective for preparing 4-H youth programs that supports the welcoming of youth and families that have no previous experience with the organization. Using the Bronfenbrenner ecological model, we explore the multiple layers of 4-H program management that support the participation of FG4-HYM in the 4-H club program. This framework provides a tool for 4-H professionals to use when assessing their program’s readiness to provide high-quality programming to all audiences, regardless of their families’ previous experience with the organization. This framework represents the foundational requirements that an organization must …

Go to article

First Prev Next Last