Digital Commons Network^™

The Global Clinical Trials Ecosystem: A Critical Evaluation And Future Outlook, Sydney-Ariel D. Muneses

Undergraduate Honors Theses

As global clinical trials expand, inconsistencies in regulatory and ethical frameworks are increasingly evident, raising concerns about economic sustainability and participant protections. Existing research attributes this surge to pharmaceutical companies seeking cost efficiencies in emerging markets but acknowledges the challenges posed by fragmented oversight across international jurisdictions. To examine these limitations, a modified Delphi approach was used to gather expert insights from key stakeholders in global clinical trials. Findings highlighted systemic inefficiencies and ethical gaps, emphasizing the need for regulatory harmonization to balance scientific rigor, economic feasibility, and equitable participant treatment. By identifying critical shortcomings and proposing strategies to align …

Programming A More Efficient Onboarding Process For New Employees, Long H. Pham

Undergraduate Honors Theses

The current onboarding process for new hires in the University of San Diego’s Shiley-Marcos School of Engineering is inefficient. There is no central location where new hires and administrators can track onboarding progress. Both parties have to manage multiple email chains and write their own reminders to keep track of everything. This leads to delays, missing deadlines, and confusion for both parties. A web-based onboarding application has been developed recently to address these issues and streamline the onboarding process for new hires. However, this application contains several accessibility issues and does not follow all of the standards for effective employee …

Planetary Health And Indigenous Sovereignty: Exploring The Theory Of Change Of The Healthy Environments And Lives (Heal) Network In Western Australia, Lucie O'Sullivan, Theoni Whyman, Mara West, Noel Nannup, Jaime Yallup Farrant, Naomi Joy Godden, Emma Leigh Synnott, Raewyn Mutch, Anita J. Campbell, Kylie Wrigley, Brad Farrant

Research outputs 2022 to 2026

This paper outlines the theory of change which underpins the Western Australian (WA) hub of the Healthy Environments and Lives (HEAL) network. HEAL is an Australian national research initiative that aims to address the health impacts of climate and environmental change. The WA hub's theory of change is focused on improving the health and well-being of the planet and people, including children, through centring Indigenous sovereignty, voices and ways of knowing and being in research, policy development and service provision. The WA hub also recognises it is essential for place-based, community-led solutions, which strengthens responses to climate and environmental change, …

Intouch Week Of May 19, 2025, New York Medical College

InTouch

• Vikas Grover, Ph.D., CCC-SLP, and Ronnie Myers, D.D.S., Named Healthcare Heroes by Westchester Magazine
• Annual Louis Del Guercio, M.D., Research Day Showcases Outstanding Surgical Research
• NYMC Celebrates Homecoming 2025 with Alumni, Students, and Campus Tours
• Teaching and Learning Symposium Brings Faculty Together to Enrich Their Educational Practice
• Philip Kuehl, Ph.D., Addresses Drug Development Problem Statements at the Neighborhood Science Seminar Series
• 185 TCDM Students Don White Coats as They Head to Touro Dental Health Clinics in New York and New Mexico
• Student Spotlight: David Zuckerman to Address Graduates Before Beginning Neurology Residency at NYU

A Fundamentally New Direction In Embolization Using Reactive Chemistry In A Swine Model, Erik Cressman, Danielle Stolley, Shubhneet Warar, Natalie W Fowlkes, David Fuentes

Faculty, Staff and Student Publications

Liver cancer carries a poor prognosis and incidence continues to increase. The main therapy for unresectable disease > 3 cm in diameter is Transarterial Chemoembolization. Unfortunately, overall survival for these patients has improved little in the past two decades. To address this, we propose a new approach using a chemical reaction in situ. We report here our results in a pilot study using a swine model. Domestic swine (n = 3) were treated in the liver with dichloroacetic anhydride in ethiodized oil. CT imaging was followed 24 h after the procedure by necropsy, histopathology, and mass spectrometry imaging. Animals tolerated the …

Evaluation Of Challenges In The Open Data Services Industry Under Uncertainty: A Methodology Based On Artificial Intelligence And Digital Transformation, Eman Sayed, Gawaher Soliman Hussein

Sustainable Machine Intelligence Journal

This paper proposes a novel multi-criteria decision-making (MCDM) framework based on Triangular Linguistic Neutrosophic Cubic Fuzzy Sets (TLNCFSs) integrated with the COBRA method to evaluate strategic alternatives addressing key challenges in the Open Data Services (ODS) industry. In the era of digital transformation and artificial intelligence (AI), open data initiatives face multifaceted obstacles, including regulatory compliance, data interoperability, public engagement, and sustainable governance. To assess effective strategies, this study considers five potential alternatives aligned with AI and digital transformation, evaluated against fourteen critical criteria spanning policy, technical, governance, strategic, economic, and human-centric dimensions. Expert assessments are collected using TLNCFSs to …

Antimicrobial And Antibiofilm Activity Of Local Wheat Bran Extract And Bacteriocin Combination Against Gastrointestinal Pathogens, Omer Natheer Abbas, Majid Rasheed Majeed

Baghdad Science Journal

Gastrointestinal microbial infections have increased especially between children and represent a community burden. The present experiment was designed to examine the combined impact of local wheat bran bioactive compounds and Bacteriocin over locally isolated pathogens including S. aureus, E. coli and C. albicans and evaluate their antimicrobial and antibiofilm eligibility. Local wheat Ibaa99 bran extract consists of phenolic compounds, phytic acid and inulin, Bacteriocin was purified from Lacticaseibacillus paracasei that was identified as a new strain (namely MOIQ35) by the 16S rRNA gene using the PCR technique and after its registration with The National Center for Biotechnology Information (NCBI). The …

Amplification Of D18s51, D8s1179, And Fes Loci Of Dna Samples Isolated From Guitar String Stored At Room Temperature, Abdul Hadi Furqoni, Anindita Riesti Retno Arimurti, Meri Meri, Ni Luh Ayu Megasari, Indah Nuraini Masjkur, Qurrota A’Yunil Huda, Intan Sari Nuraini, Luluk Hermawati

Baghdad Science Journal

The act of criminality is an unlawful behavior that constitutes a criminal offense. Criminals use various ways to hide evidence at the crime scene. Forensic experts often find DNA on items found at the crime scene, one of the types of evidence is a guitar. Guitar is one of the musical instruments often played by humans that can be used as a comparison. Methods: This study used 18 guitar string samples that had been used for five minutes and incubated at room temperature. The 18 samples were then divided into three groups, in which each group consisted of six samples …

Downregulation Of Biofilm Formation Genes In Some Pathogenic Bacteria By Extracts From Two Algal Genera, Nishtiman S Hasan, Janan J Toma, Abdulilah S Ismaeil, Suzan A Shareef, Muhsin J Abdulwahid

Baghdad Science Journal

Most infectious diseases are primarily caused by the growth of microorganisms called biofilms. The formation of bacterial biofilms enables microorganisms to inhabit biotic and abiotic surfaces which increases their resistance to antimicrobials. To control this issue, there is a critical need for novel approaches and compounds can suppress the expression or regulation of virulence genes. A potential method for disarming rather than eliminating bacterial pathogens is antivirulence therapy based on the blockage of biofilm pathways. In current study, the action of water, diethyl ether and acetone extraction on two types of algae namely Scenedesmus quadricauda and Chlorosarcinopsis eremi in their …

The Effect Of Bio And Nano Fertilizer On Growth And Yield Of Basil Plant And Its Content Of Active Ingredients, Radhiyah Ali Hasan Ahmad, Hayder Abdulmunem A. Turk, Suha Dhia Abid Ali Twaij

Baghdad Science Journal

A factorial experiment was conducted at the College of Education for Pure Sciences Ibn al-Haitham/University of Baghdad for the 2023 growing season to study the effect of the biofertilizer represented by the mycorrhizae vaccine and the NPK Nano fertilizer on some indicators of vegetative and root growth, yield, and volatile oil production of the basil plant, Ocimum basilicum L., the experiment included two factors. The first factor was mycorrhizae inoculum at 2 levels: 0 (no addition) and an addition of 25 g plant^–1, as the seeds were inoculated upon planting. The second factor was spraying the plant’s shoots …

Sequence Conservation Of Suppressor Of Ikk Epsilon Phosphorylation Sites, Kaydence M. Isaacs

Undergraduate Honors Theses

Suppressor of IKK epsilon (SIKE) is a protein that is implicated in immune response signaling pathways. SIKE interaction networks suggest roles in cell motility and macromolecular complexes mediating kinase/phosphatase activity. In this project, we aim to better understand the function of SIKE by analyzing amino acid sequences across different species. In human SIKE, viral infection leads to phosphorylation of SIKE at defined serine residues. Comparing SIKE sequences, and specifically these phosphorylation sites, allows us to discover its ancestral connections to innate immune function. This has particular applications in bridging the evolutionary gap between fungi and metazoa SIKE sequences. Multiple sequence …

Decarbonized Shipping: Is It The Best Sustainable Shipping Solution?, Olivia Akers

Sustainable Supply Chain Management

In the era of globalization and the fourth industrial revolution, the maritime shipping industry has grown exponentially in the twenty-first century. In fact, 90% of today’s goods travel across the ocean before reaching the end consumer, meaning that ocean transportation of goods contributes significantly to overall environmental impacts on the ocean. Awareness of this impact has increased as humans strive to eliminate unsustainable practices in an effort to protect the long term health of our planet. Decarbonized shipping has been proposed as a possible solution for unsustainable shipping practices, and the goal of this chapter is to evaluate this solution …

Ccaat/Enhancer-Binding Proteins Α And Β Regulate Ovulation And Gene Expression Via Dose- And Stage-Dependent Mechanisms, Hanxue Zhang, Rainer B Lanz, Jimmy Dhillon, Paul D Soloway, Bo Shui, Yi Athena Ren

Faculty, Staff and Students Publications

The preovulatory luteinizing hormone (LH) surge orchestrates complex cellular and molecular events leading to ovulation. CCAAT/enhancer-binding proteins α and β (C/EBPα/β) are transcription factors acutely induced by the LH surge and crucial for ovulation and granulosa cell luteinization. However, biological processes (BPs) and their regulatory mechanisms downstream of C/EBPα/β in the preovulatory ovary are not completely understood. To address this knowledge gap, we generated Cebpa/bfl/fl;Pgr-Cre mutants and compared them with Cebpa/bfl/fl;Cyp19a1-Cre mutant female mice: Cebpa/bfl/fl;Cyp19a1-Cre mutants have undetectable levels of C/EBPα/β throughout the preovulatory stages and do not ovulate, aligning with previous reports; and Cebpa/bfl/fl;Pgr-Cre mutants present gradual depletion of …

Development And Evaluation Of A Simple Human Body Link Model Considering The Degrees-Of-Freedom Of Shoulders, Mizuki Takeda, Yuki Saito, Kaiji Sato

Progress in Scale Modeling, an International Journal

Modeling of the human body is widely utilized in the field of human–robot interaction, warranting the development of a simple model to measure and recognize the human body movements. To this end, a two-dimensional (2D) human body link model in the sagittal plane has been used to represent the human body with rotating joints and links connecting these joints. The joint positions can be determined by using the coordinates of a limited number of points on the links and estimated using a few sensor outputs when the links are of constant length. However, models with constant link lengths may result …

Table Of Contents

DePaul Law Review

No abstract provided.

The Tax Adviser, Volume 15, Number 1, January 1984

Tax Adviser

No abstract provided.

Foreign Branch Incorporations: Does Bliss Dairy Warrant A Reexamination Of Hershey Foods?, Robert Willens

Tax Adviser

No abstract provided.

Wild Women, Wild West: Queer Women’S Sexuality And Gender Presentations On The Western Frontier, Michaela White

Undergraduate Theses and Capstone Projects

No abstract provided.

An Examination Of The Effect Of Cloth Material On The Efficiency And Success Of Tick Dragging Protocol In Lynchburg Va., Hyden Draughon

Undergraduate Theses and Capstone Projects

Ticks serve as a major vector of arthropod-borne pathogens that could affect human populations. Ixodes scapularis, Amblyomma americanum, Dermacentor variabilis, and Haemaphysalis longicornis populations have been commonly reported in the state of Virginia, and can carry pathogens potentially fatal to humans. I. scapularis serves as a vector of Borrelia burgdorferi (the bacterium that causes Lyme disease), A. americanum has been found to carry Ehrlichia chaffeensis (the bacterium that causes Human Monocytic Ehrlichiosis), D. variabilis can carry Rickettsia rickettsii (the bacterium that causes Rocky Mountain Spotted Fever), and H. longicornis has been found to transmit protozoan Theileria orientalis to livestock. Over …

25 Conference Program - Advances In Optics For Biotechnology, Medicine And Surgery Xviii, Melissa Skala, Summer Gibbs, Stefan Andersson-Engels

Advances In Optics for Biotechnology, Medicine And Surgery XVIII [2025]

No abstract provided.

25 Conference Program - Bio-Char Iv, Franco Berruti, David Chiaramonti, David Chiaramonti, Johannes Lehmann

Bio-Char IV

No abstract provided.

Co-Parenting With The Land In Amazonian Ecuador: Speech, Breath, And Personhood Among The Napo, Runa, Kate R. Nielsen

Anthropology ETDs

This paper explores the processes of personhood in lowland Amazonia and specifically, Kichwa-speaking communities in Ecuador. In lowland Amazonia, personhood is developed through a multitude of social processes in contrast to the Western perception of birth as the defining moment of personhood. As noted in the current literature, an infants' personhood emerges through their relationships with family and community This thesis investigates whether a similar process exists among Kichwa speakers. While Kichwa infants undergo processes akin to their lowland Amazonian neighbors, such as body manipulation and food taboos, shared breath, often through speech, is vital to the ebbs and flows …

Seeing Through The Incense Smoke: Understanding The Meanings Of Ancestral Rites In Vietnam For The Sake Of A Pastoral Approach In Christian Mission, J.P. Cima

Doctor of Philosophy Dissertation

Cima, J.P. “Seeing Through the Incense Smoke: Understanding the Meanings of Ancestral Rites in Vietnam for the Sake of a Pastoral Approach in Christian Mission.” Ph.D. diss., Concordia Seminary, 2025. 285 pp.

The veneration of ancestors at family altars has long been a defining feature of everyday Vietnamese life that poses a critical missiological problem for Christian mission in Vietnam. May Christians participate in ancestral veneration rituals? Current and historical responses to this question, among Protestants and Catholics alike, have not been uniform. Moreover, many responses have been based on assumed or oversimplified understandings of the rites’ meaning which recent …

Pollinator Plant Communities Within Restored Montane Longleaf Pine Ecosystems, Hanen Van Rossem

Master's Theses

Historically the fire-dependent and biodiverse longleaf pine (Pinus palustris) ecosystem was the dominant ecosystem of the Southeastern US. This ecosystem’s range was massively reduced due to land conversion and fire exclusion, causing the decline of many native species. Efforts to restore and protect longleaf pine stands are now ongoing with the goal of expanding habitat and refuge for threatened species. Differences in restoration practices and prior land use may influence the extent to which restored habitat patches can support pollinators and their plants. This study compared pollinator plant biodiversity between restored neighboring montane longleaf pine stands that differed in …

Engagement In Responsible Conduct Of Research: A Descriptive Case Study Of The Factors Of Organizational Culture And Implementation Drivers That Influence Research Integrity Practice, Cortni Beth Romaine

Doctor of Philosophy in Translational Health Sciences Dissertations

This qualitative descriptive case study investigates the relationship between organizational culture and the Responsible Conduct of Research (RCR) across multiple research institutions. Utilizing elements of the Cultural Dynamics Model and the Implementation Drivers Framework, the study examines how institutional structures and cultural norms shape research integrity practices. Data collection involved in-depth interviews with faculty, postdoctoral researchers, and graduate students, as well as an artifact review of institutional policies, training resources, and guidance for research best practices.

Findings revealed three key themes: (1) Microculture Experiences, where RCR engagement is largely dictated by localized lab cultures, with principal investigators (PIs) playing a …

Transnational Methodological Engagements With Artistic Narratives: Challenging Hierarchies And Building Community, Lauren Stetz

The Qualitative Report

Through the analysis Violence Against Women Art Map Project, a publicly accessible online platform that utilizes data visualization to understand the contextual complexities of violence against women (VAW), this article explores how comics and narrative artworks can be utilized to provide voice on sensitive or controversial subject matter, challenge accepted societal hierarchies and norms and build community. Considering social media as a transnational dialogic space, graphic works within online spaces can provide qualitative researchers with the potential to expose the multilayered and entangled experiences of individuals across cultures and to interrupt frequently silenced issues that often go unwitnessed and unspoken. …

Detection Canines: An Insight Into Investigative Working Dogs, Adriana Pliego

Themis: Research Journal of Justice Studies and Forensic Science

In a comprehensive exploration of detection canines, this paper aims to research the depth of their utilization by many investigative agencies and fields. A relevant case is discussed to present the application of detection canines and how they are useful for investigative measures. Shedding light into the various components of detection canines, this paper will discuss desirable canine characteristics that are sought out. On the other hand, undesirable characteristics are also discussed to inform recruiters of which attributes they should opt out of. This paper continues to discuss the roles and capabilities of detection canines given their unique potential. Then, …

Forensic Psychology Of Serial Killers, Karla Suarez

Themis: Research Journal of Justice Studies and Forensic Science

Many serial killers share patterns in psychological and neuropsychological disorders and behaviors. These behaviors and patterns should be recognized and acknowledged to understand why serial killers murder without remorse or guilt. It is important to discuss matters such as common patterns, typologies, and characteristics within serial killers. After looking at these essential aspects of serial killers, common neurodevelopmental disorders, brain damage, and biological epigenetics will be further explored. In order to fully assess this topic, forensic psychology and behavioral analysis are essential to aid in understanding serial killers and how their brains function to lead them to the actions that …

So Much More Than Summer Camp: The Importance Of Environmental Education At Nature Centers, Olivia Upton

Undergraduate Theses and Capstone Projects

Education in the U.S. currently faces a deficit in the promotion and proper teaching of climate change curriculum. Obvious gaps are created by a lack of clear teaching standards for environmental education, the American political machine stirring up controversy over the legitimacy of climate change, or teacher preferences. As climate change is considered one of the greatest threats facing humanity today, there is a need to educate people, especially younger generations, in order to navigate future challenges and make informed decisions. Nature centers offer the ideal location for the promotion of climate change education based on their direct connection to …

Observing The Prevalence Of Wolbachia Found In Tick Species From The Central Virginia Region, Madison Hoover

Undergraduate Theses and Capstone Projects

Research has found that ticks are considered the second highest global vector of disease. Ticks can serve as a vector for pathogens such as Rickettsia rickettsii (Rocky Mountain Spotted Fever), Borrelia burgdorferi (Lyme Disease), Borrelia miyamotoi (B. miyamotoi disease) and Borrelia hermsii (tick-borne relapsing fever). Tick species such as Dermacentor variabilis (American Dog ticks), Amblyomma maculatum (Gulf Coast ticks), Amblyomma americanum (Lone Star ticks), Ixodes scapulari (Black legged ticks), and Ixodes affinis can be found within the southeastern Virginia region. Arthropod hosts that possess Wolbachia can have their reproduction negatively impacted through methods such as Parthenogenesis, Male Killing, Feminization, and …