Digital Commons Network^™

Histological And Histochemical Study Of The Salt Glands In Geese (Anser Anser): Are There Receptor Cells In Salt Glands?, Şahi̇n Aslan, Di̇lem Gülece Ermutlu, Serap İlhan Aksu, Serap Koral Taşçi, Turgay Deprem

Turkish Journal of Veterinary & Animal Sciences

The regulation of solutes occurs not through the skin but via salt glands located in the nose and kidneys in reptiles and birds. This study aimed to investigate and elucidate the histological structure of the salt glands in domestic geese, and to characterize their ducts and cellular components in detail.Crossmon’s triple staining technique, hematoxylin and eosin (H&E), periodic acid-Schiff (PAS), combined alcian blue, and Kluver– Barrera stains were used for the histological investigations.The outer surface of the organ was enclosed by connective tissue, and the capsule subdivided the tissue into bulbs. Nerve fibers and endings were observed within the capsule …

Oxygen Saturation Targeting In The Neonatal Intensive Care Unit, Faeq Almudares, Bheru Gandhi, Jonathan Davies, Xanthi Couroucli, Natalie Villafranco, Nidhy Paulose Varghese, Milenka Cuevas Guaman, Charleta Guillory, Binoy Shivanna

Faculty, Staff and Students Publications

Oxygen (O2) is vital for cellular development, function, proliferation, and repair, underscoring its critical role in organogenesis. Both hypoxia (reduced tissue O2) and hyperoxia (excess tissue O2), when prolonged, can trigger inflammation and oxidative stress, contributing to acute and long-term cardiopulmonary and neurodevelopmental morbidity. In sick neonates, immature defense mechanisms and coexisting morbidities demand nuanced and sometimes opposing strategies for O2 saturation targets and therapeutic titration. Most current neonatal O2 targeting guidelines are based on animal models or small clinical studies, resulting in recommendations with limited evidence. This narrative review aims to provide an updated overview of the physiological roles …

Sunrise At The Salton Sea: Environmental Justice, Land Use Change, And Hydrosocial Dynamics Of Solar Energy Transitions In The Imperial Valley, California, Dustin Mulvaney, James J.A. Blair, Alida Cantor

Faculty Research, Scholarly, and Creative Activity

California's Imperial Valley, with lithium-rich geothermal brines, extensive flat agricultural fields with abundant desert sunshine, and access to transmission lines, is a leading case to explore interconnected themes around just energy transitions. Despite being the poorest county in California and one of the smallest, Imperial already provides 15% of the state’s solar electricity, and the region as a whole represents on the order of 25% of the state’s electric power capacity. This paper brings to light frictions over solar energy development that have emerged over the history of solar power development in the southern Salton Sea region. It describes the …

Pesticides As Multiple Stressors To Bivalves And Echinoderms, Alexandra Gabrielle Tissot

Dissertations and Theses

Pesticides are ubiquitous in aquatic environments, alongside numerous contaminants and other stressors that can result in combined exposure to target and non-target organisms. Nevertheless, traditional toxicity studies quantify the effects of these compounds at an individual level, and to a narrow range of traditional test organisms. Through this dissertation, I explored the presence and effects of commonly detected pesticides of concern in the Pacific Northwest in order to realistically quantify potential effects from combined stressors. In Chapter 2, I demonstrated my background knowledge on these select pesticides (atrazine, bifenthrin, diuron, indaziflam, and imidacloprid), including their chemical and physical properties. Using …

“Any Black Man Will Do”: A Transparency Framework For Eyewitness Identification In The Facial Recognition Technology Era, Ariam O. Kiflemariam

Washington Journal of Social & Environmental Justice

No abstract provided.

Justice Lewis Powell’S Quiet Luxury: From Bakke To Sffa, Lucille A. Jewel

Washington Journal of Social & Environmental Justice

No abstract provided.

[2025 Honorable Mention] The White Savior Trope In A “Post-Racial” Era, Gannon Camp

Ethnic Studies Research Paper Award

This paper explores how the media's promotion of the white savior trope, particularly following Obama's election, contributed to a false perception among Caucasians that significant racial issues had been resolved, despite evidence to the contrary.

‘You’ And ‘We’ In #Womanlifefreedom: A Corpus-Based Discourse Analysis Of Collective Identities And Speech Acts In The Twitter’S Discourse Of Iranian Protests, Kimiya Roohani

Peace and Conflict Studies

This paper applies corpus linguistic discourse analysis to approach the social media discourse of a recent political movement in Iran, known as #WomanLifeFreedom and Mahsa Amini. The movement included vast protests in different parts of Iran and went viral on an international scale. Protesters relied heavily on social media, particularly Twitter, to determine strategies and support each other during the expansive calls. To address the discourse shaped in that platform, a corpus was compiled from the Twitter posts, named Mahsa Amini Tweets Corpus (MATC). Using this data collection and analysis method, the endeavour was to obtain a balance between quantitative …

In Search Of Robe & Crown (Jamiaposh)

Old name/logo items (letterheads, seals, posters, etc.)

No abstract provided.

Academic Senate - Agenda, 6/3/2025, Academic Senate

Academic Senate Agendas

No abstract provided.

Reform Vs Revolution: Revisiting Original Institutionalist’S Axiology, Jacob Powell

Working Papers

No abstract provided.

Investigating The Consequences Of Conjugated And Secreted Isg15 On Coronavirus Pathogenesis, Mudassir Syed Ali

Dissertations

Coronaviruses have evolved a breadth of mechanisms to antagonize host innate immune responses. One widely studied mechanism is the ability to deconjugate ISG15 from target proteins in a process called deISGylation, which is catalyzed by the papain-like protease (PLP) domain of viral non-structural protein (nsp) 3. Since PLP activity is required for viral replication, it has been challenging to generate an infectious virus with a PLP that maintains protease activity but has lost deISGylase activity. In this study, we generated a chimeric MHV-A59 with its PLP2 domain replaced with that of the human coronavirus HKU1, which has been documented to …

Emerging Therapeutic Potential Of Fisetin For Nephrotoxicity, Kidney Injury, And Nephropathy: A Systematic Review, Saeed Mohajeri, Alizamen Salehifard Jouneghani, Saeid Heidari-Soureshjani, Catherine M.T. Sherwin, Faramarz Beigi

Pediatrics Faculty Publications

INTRODUCTION/OBJECTIVE: Kidney diseases cause high morbidity and mortality worldwide. This study investigated the mechanistic effects of Fisetin (FIS) on nephrotoxicity, kidney injury, and nephropathy induced by drugs, toxic chemicals, diabetes, lupus, diet, ureteral obstruction, and ischemic situations.

METHODS: To identify pertinent articles published before Oct 1, 2024, a comprehensive electronic search was performed across several databases, including MEDLINE/PubMed, Embase, Cochrane Library, Web of Science, and Scopus. After establishing clear inclusion and exclusion criteria, studies that met the research objectives were selected. Data were extracted and analyzed, documenting study characteristics, methodologies, and biological mechanisms.

RESULTS: Antioxidant benefits were evident with increased …

Don’T Take St. Anselm For A Marriage Therapist: The Utility Of Substitutionary Atonement Theology In Light Of Feminist Critiques, Abigail Elizabeth Livengood

Honors Projects

In light of feminist critiques from the twentieth and twenty-first century, this paper returns to Anselm’s Cur Deus Homo to examine the earliest expression of the Substitutionary Atonement Model. While acknowledging the harmful rhetoric attached to the model which has been brought to light by feminist theologians, this work examines Anselm's characterization of God, Jesus, and suffering from within his medieval worldview. In addition, this paper utilizes understandings of Christ held by historical women and survivors themselves to provide further context for Anselm’s understanding. Ultimately, this paper asserts that while feminist theologians raise important concerns about the dangers of Substitutionary …

The (Dis)Continuity Of Meaning In John Dewey’S Experience And Nature, Harrison S. Jackson

Center for Dewey Studies Essay Award

Experience and Nature proposes a naturalistic empiricism emphasizing continuity. This paper will argue that this continuity is threatened by Dewey’s anthropocentric in its account of meaning, which is only found in humans but is necessary for the perception of objects, communication, and social existence. Given contemporary research in ethology, Dewey’s denotative method requires a modification of this account. I will propose Merleau-Ponty’s notion of sense or the neuroscientific theory of enactivism as supplements preserving embodiment and social communication while being more continuous. Finally, I examine some recent applications of Dewey’s naturalism and show how they modify this account of meaning.

Biomarker-Guided Imaging And Ai-Augmented Diagnosis Of Degenerative Joint Disease, Rahul Kumar, Kyle Sporn, Aryan Borole, Akshay Khanna, Chirag Gowda, Phani Paladugu, Alex Ngo, Ram Jagadeesan, Nasif Zaman, Alireza Tavakkoli

Department of Medicine Faculty Papers

Degenerative joint disease remains a leading cause of global disability, with early diagnosis posing a significant clinical challenge due to its gradual onset and symptom overlap with other musculoskeletal disorders. This review focuses on emerging diagnostic strategies by synthesizing evidence specifically from studies that integrate biochemical biomarkers, advanced imaging techniques, and machine learning models relevant to osteoarthritis. We evaluate the diagnostic utility of cartilage degradation markers (e.g., CTX-II, COMP), inflammatory cytokines (e.g., IL-1β, TNF-α), and synovial fluid microRNA profiles, and how they correlate with quantitative imaging readouts from T2-mapping MRI, ultrasound elastography, and dual-energy CT. Furthermore, we highlight recent developments …

Reading For Pleasure, Writing For Impact: A Reflection On How An Assessment Task Fosters Advocacy In An Undergraduate English Service-Learning Module, Dermot Burns

Irish Journal of Academic Practice

Service-learning is a valuable pedagogy through which to facilitate and nurture the skills and knowledge pertaining to advocacy. A unique approach to foster this learning is being practised in the Discipline of English at University of Galway through its assessment design for an undergraduate module entitled ‘Service-learning: reading and writing with primary school children’. This paper establishes the significance of advocacy in service-learning and argues for the relevance of advocating for Reading for Pleasure with children. It describes how a mid-term assignment encourages students to share both their practical experiences in a local primary school and their emergent expertise, gained …

Representations Of Queer Cowboys In History, Literature, And Film, Olivia Black

History & Classics Undergraduate Theses

My senior thesis focuses on showing the existence and erasure of queerness in American cowboys. The first chapter uses two journals from two different cowboys as well as an article from a Denver newspaper to establish what being queer looked like to cowboys and how that queerness continued after the end of the Frontier. Chapter two focuses on interpretations of cowboys in literature using two fictional cowboy stories which included the queer aspects of cowboy life as well as autobiographical and fictional cowboy poetry that confirmed explicit homosexual activity and revealed a shift in public views on being queer. The …

An Antibody Biomarker Associated With Onchocerca Volvulus Microfilariae Identified By Proteomic Analysis Of Parasite Tissues Isolated From Paraffin Embedded O. Volvulus Nodules By Laser Capture Microdissection, Sarah E Greene, Kerstin Fischer, Lucia S Di Maggio, Bruce A Rosa, Yuefang Huang, Irina Diekmann, Byoung-Kyu Cho, Jessica Lukowski, Young A Goo, Makedonka Mitreva, Nicholas Opoku, Gary J Weil, Peter U Fischer

2020-Current year OA Pubs

Onchocerciasis (river blindness), a neglected tropical disease caused by the filarial nematode Onchocerca volvulus, impacts millions of people in sub-Saharan Africa. The WHO coordinates global efforts to eliminate onchocerciasis and has prioritized development of improved diagnostic tests to aid these efforts. To find new microfilarial-associated diagnostic targets to help identify active infections, we used laser capture microdissection to isolate embryonic stages from histologic sections of O. volvulus worms in subcutaneous nodules excised from onchocerciasis patients. Proteomic analysis identified 2,512 O. volvulus proteins in those tissues, including 264 found only in the microfilariae (Mf). From this pool of diagnostic candidates, we …

Current Issues In Oral Health: Introduction To The Special Issue, Nejat Düzgüneş

Pacific Faculty Work

No abstract provided.

Creation Of An Open Access Textbook, Sue Ann Gardner

University of Nebraska-Lincoln Libraries: Presentations

Slide presented during the PRCA Research Celebration, June 3, 2025, in the University Libraries, University of Nebraska-Lincoln titled Creation of an Open Access Textbook, about the development and publication of Concepts in Animal Parasitology, co-edited by Scott L. Gardner and Sue Ann Gardner and published by Zea Books (Lincoln, Nebraska, USA) in 2024.

Artificial Intelligence And Astronomy: Lab Manual For Generative Ai-Based Learning Activities, Vasiliy Znamenskiy

Open Educational Resources

This lab manual introduces community college students to the intersection of artificial intelligence (AI) and astronomy through hands-on, inquiry-based activities. It explores how generative AI platforms—ranging from text-based chat systems to image and video generators—can enhance scientific understanding, creativity, and critical thinking in space science education. Students engage with tools such as ChatGPT, Gemini, DALL·E, and Synthesia to formulate and evaluate astronomy-related questions, generate scientifically inspired visualizations, and produce dynamic representations of cosmic phenomena. Through structured exercises, the manual promotes digital literacy, fosters analytical skills, and illustrates how AI assists in astronomical research, including data analysis, image enhancement, spacecraft autonomy, …

Stroke Survivors: Predicting Cognitive Outcomes By Stroke Severity, Caregiver Factors, & Social Determinants Of Health, Jason Alexander Blake

All ETDs from UAB

Physical and cognitive disabilities are common following a stroke, often leading to significant changes in survivors' daily lives and increasing dependency on caregivers. These changes can include involuntary retirement, loss of independence, and decreased social engagement, which may necessitate adjustments in living arrangements and long-term care. This dissertation investigates the predictors of cognitive outcomes in stroke survivors, with a particular focus on the roles of stroke severity and caregiver factors. Utilizing data from the REasons for Geographic and Racial Differences in Stroke (REGARDS) project, this research captures the different predictors of post-stroke cognition through biennial assessments. Through longitudinal studies, this …

The Role Of B Cells In A Mouse Model Of Multiple System Atrophy, Gabrielle Childers

All ETDs from UAB

Multiple system atrophy (MSA) is a rare, fast progressing, debilitating and ultimately fatal movement disorder. The pathological hallmark of MSA disease is the aggregation and misfolding of alpha-synuclein (α-syn) protein in the cytoplasm of oligodendrocytes, termed glial cytoplasmic inclusions (GCIs). Accumulation of these GCIs result in progressive demyelination and neurodegeneration of the striatonigral and olivopontocerebellar regions of the brain. Currently, no therapeutics have been approved that slow or halt the progression of this devastating disease. Neuroinflammation, has been increasingly appreciated as a key neuropathological feature of disease, especially activation of tissue resident innate immune cells. Recently, evidence of adaptive immune …

Modeling The Mark 26 Guided Missile Launching System: Exploring Its Role In U.S. Naval Doctrine In The Late Cold War, Ryan Matthew Cabico

Theses and Dissertations

The Mark 26 Guided Missile Launch System was an innovative and modular upgrade from previous systems for the United States Navy at a critical development point during the Cold War. Its incorporation into the Virginia-Class, especially the USS Arkansas, exemplified the rapidly evolving scope and demands of naval warfare in the modern era, and the requirements of individual vessels and component parts of the Navy to fulfill U.S. naval doctrine in this era. This same rapid evolution in technology and the global political landscape would ultimately seal the fate of the Mark 26 and USS Arkansas, with their designed innovations …

Cardiac-Derived Fibroblast Growth Factor 23 Contributes To Physiologic And Pathologic Cardiac Remodeling, Isaac Daniel Campos

All ETDs from UAB

Chronic Kidney Disease (CKD) is a global health risk that increases patients’ risk for premature mortality and is accompanied by pathologic cardiac hypertrophy and fibrosis. Declining kidney function results in elevations of serum phosphate and Fibroblast Growth Factor (FGF) 23, a bone-derived phosphaturic hormone. Hyperphosphatemia and elevated FGF23 are associated with cardiovascular mortality in CKD. FGF23 can directly target cardiac myocytes via FGF Receptor (FGFR) 4 and induce cardiac hypertrophy and blocking FGFR4 signaling in CKD models reduces cardiac hypertrophy, but not fibrosis. FGF23 elevations are also observed following exercise and during pregnancy, two scenarios of physiologic hypertrophy not associated …

Unframing Spatial Presence And Resonating Aesthetic Presence : A “Continuous Interaction” Of Visitor Engagement With Chinese Art, Yi Zhu

Lingnan Theses (MPhil & PhD)

Digital technologies, as a prevalent method of display in museums, has been widely used in the presentation and creation of Chinese art, such as software, hardware, and interactive installations in exhibitions. According to Peng Feng (2022), digital technologies can effectively disseminate Chinese classical artworks while enriching visitors’ experience, enhancing their perceptions of aesthetic concepts and facilitating their understanding of the artworks. However, current studies are primarily focused on the social and cultural background information conveyed by the objects, rather than the visitor experiences in the process of interaction with the artworks. Digital technologies can engage visitors through active interaction with …

Pyruvate Dehydrogenase Kinase 4 Mediates Sex Specific Outcomes In Sepsis Induced Cardiomyopathy, John Yap

Dissertations

During sepsis, males often experience worse cardiac outcomes than females. Here, we identified pyruvate dehydrogenase kinase 4 (PDK4) as a key contributor to this disparity. PDK4 is a mitochondrial protein that regulates glucose utilization by inhibiting pyruvate dehydrogenase (PDH). Using a mouse model of endotoxemia, we induced acute inflammation with a sublethal dose of lipopolysaccharide (LPS), which caused cardiac dysfunction and significantly increased myocardial PDK4 expression in males but not females. Cardiac-specific PDK4 overexpression promoted LPS-induced cardiac dysfunction in both sexes, whereas cardiac-specific PDK4 knockout provided protection. In wild-type males, LPS disrupted cardiac metabolism by decreasing PDH activity and fatty …

Restoration Of The Tumor Suppressor Function Of Y220c-Mutant P53 By Rezatapopt, A Small-Molecule Reactivator, Anna M Puzio-Kuter, Lizhong Xu, Mary Kate Mcbrayer, Romyr Dominique, Hongju H Li, Bruce J Fahr, Alyssa M Brown, Amy E Wiebesiek, Brandon M Russo, Chris L Mulligan, Hong Yang, Josh Battaglia, Kimberly A Robell, Dafydd H Thomas, Kuo-Sen Huang, Alexander Solovyov, Benjamin D Greenbaum, Jonathan D Oliner, Thomas W Davis, Melissa L Dumble, Melissa L Johnson, Shunbin Xiong, Peirong Yang, Guillermina Lozano, Marc M Fellous, Binh T Vu, Alison M Schram, Arnold J Levine, Masha V Poyurovsky

Faculty, Staff and Student Publications

Restoration of the tumor suppressor function of tumor-associated p53 mutants, including the Y220C substitution, has posed a significant challenge for therapeutic discovery. In this study, we describe rezatapopt (PC14586), part of a series of compounds designed to reactivate the p53 Y220C mutant. These compounds restore p53 tumor suppressor function by correcting its conformation and enabling it to bind DNA and activate downstream target genes, thus inducing antiproliferative changes in tumor cells. Our findings are supported by biochemical and structural analysis, in vitro and in vivo transcriptomics, and functional data, revealing the recovery of multiple aspects of the wild-type p53 program. …

Comparison Of Open And Laparo-Endoscopic Repair Techniques For Patients With Bilateral Inguinal Hernias, Divyansh Agarwal, Tina Bharani, Nora Fullington, Lauren Ott, Kortney Hodgson, Daelyn Mcclain, Kaela Blake, Michael Reinhorn

Department of Surgery Faculty Papers

INTRODUCTION: For primary bilateral inguinal hernias, international guidelines favor a laparoscopic posterior mesh repair due to relatively lower risk of acute and chronic pain, faster recovery, and favorable biomechanical properties compared to open anterior approaches (Lichtenstein, plug and patch, etc.). However, studies comparing open mesh-based bilateral inguinal hernia repairs to bilateral laparoscopic and robotic mesh-based approaches are limited. The Abdominal Core Health Quality Collaborative (ACHQC) registry includes longitudinal data on bilateral inguinal hernia repairs performed via open as well as laparo-endoscopic approaches. We hypothesize that outcomes for bilateral inguinal hernia repair are similar between open and laparo-endoscopic approaches in the …