Digital Commons Network^™

Artificial Intelligence And Privacy, Daniel J. Solove

Florida Law Review

This Article aims to establish a foundational understanding of the intersection between artificial intelligence (AI) and privacy, outlining the current problems AI poses to privacy and suggesting potential directions for the law’s evolution in this area. Thus far, few commentators have explored the overall landscape of how AI and privacy interrelate. This Article seeks to map that territory.

Some commentators question whether privacy law is appropriate for addressing AI. In this Article, I contend that although existing privacy law falls far short of resolving the privacy problems with AI, privacy law properly conceptualized and constituted would go a long way …

Examining The Anxiolytic Effects Of Flavonoids In Passionflower: A Gut-Brain Axis Perspective, Khelen R. Walsh

PSU McNair Scholars Online Journal

This literature review investigates the influence of Passiflora incarnata on the Gut-Brain Axis, focusing on the role of flavonoids and the specific biological mechanisms involved in this process. The study aims to identify Passiflora incarnata as a practical, non-harmful, and cost-effective alternative to current modern anxiety medications. This study also emphasizes the need for further clinical trials to integrate Passiflora incarnata further into healthcare settings. Using a narrative review approach, this analysis will examine pre-existing empirical articles, all of which have been found on credible sites, are peer-reviewed, and have been published within the past twenty-five years. The data discussed …

Social Emotional Learning With Children And Social Cognitive Therapies Used In Treatment For Schizophrenia: What Is The Relationship Between Them?, Lynette Marie Lubiak

PSU McNair Scholars Online Journal

Why has mental illness in our children let alone society increased so significantly? In this paper I am doing a lit review to understand the need for a structured lesson plan of Social Emotional Learning (S.E.L.) and incorporating some techniques of social cognitive therapies for our children. This will be understood by comparing social cognitive therapies in Schizophrenia treatment that rewires healthy neural pathways from miswired neural pathways that are not functional in schizophrenia and the impact on a person with schizophrenia having difficulties to integrate into society while coping with their illness. I will do this by analyzing Theory …

Phenotypic Characterisation Of Staphylococcus Aureus And Escherichia Coli Clinical Isolates And Their Susceptibility To Targeted Bacteriophages, Shauna K. Hurley, Laura O'Connell, Michael Callanan, Aidan Coffey

ORBioM (Open Research BioSciences Meeting)

Abstract:

Antibiotic resistance (AMR) is the one of the biggest threats facing humans and animals in the 21^st century. This has been caused by the overuse and misuse of antibiotics leading to the desperate need for innovative therapeutic alternatives. Research is ongoing regarding the use of bacteriophages as a possible viable antimicrobial agent. However, various limitations exist which hinder their use including their narrow host range. This limitation poses a significant threat to the development of phage therapies as it requires phenotypic characterisation of clinical isolates to ensure compatibility between strains and phage. This study outlines phenotypic characterisation of …

Selecting For Less: How Much Methane Can We Truly Breed Away?, Sean B. Crowley

ORBioM (Open Research BioSciences Meeting)

Background

Genetic selection has potential to reduce enteric methane emissions from cattle, but a key challenge is determining how much of the genetic variation in methane traits is independent of traits already targeted in breeding programs, such as feed intake and growth.

Methods

Methane and carbon dioxide emissions were recorded in 1,700 crossbred, indoor-fed beef cattle using Greenfeed systems. Performance data included feed intake, metabolic liveweight, average daily gain, carcass weight, and ultrasound and skeletal traits. Genetic parameters and correlations among traits were estimated using animal linear mixed models to quantify the independence of methane-related genetic variation.

Results

Daily methane …

Exploiting Genomics To Advance Genetic Gain For Reproductive Traits In Sheep, Mujibur Rahman

ORBioM (Open Research BioSciences Meeting)

Poor reproductive performance has a negative impact on the profitability of sheep production systems with the number of lambs reared highlighted as a key driver of farm profitability. Nevertheless, the genetic improvement of reproductive traits in sheep has been constrained by their low heritability and pleiotropic nature. Understanding the underlying genetic architecture can improve genomic prediction estimates and enhance genetic gain.

This study will utilize large-scale genomic and phenotypic datasets to enhance genetic gain in sheep reproductive traits through four approaches: 1) to determine the effect of inbreeding depression on reproduction, 2) to identify causal variants impacting reproductive performance through …

An Evaluation Of The Monospot Test To Diagnose Epstein-Barr Virus Associated Infectious Mononucleosis (Ebv-Im), Patrick Naughton

ORBioM (Open Research BioSciences Meeting)

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Abstract

Aim

To calculate the performance characteristics of the Clearview^® IM II Monospot [heterophile antibody (HA) test] to determine Infectious Mononucleosis associated with Epstein-Barr Virus (EBV-IM) in clinically suspect patients.

Methods

The laboratory results of 420 patients tested for HAs over a two-year period (2018-2019) in a single testing centre in Ireland were analysed. A novel multivariant test (reference) model was designed to determine true positive and negative EBV-IM cases. A cohort of 50 Monospot results were compared against this reference model and the test’s performance characteristics determined.

Results

The Monospot test proved reasonably specific but insensitive …

Maximum Convergence Voting: Madisonian Consitutional Theory And Electoral System Design, Edward B. Foley

Florida Law Review

The Madisonian political philosophy upon which the U.S. Constitution rests did not supply the nation with a well-developed theory of electoral procedures. Instead, Madisonian philosophy concentrated on the separation of powers and other elements of constitutional architecture, including federalism, in order to prevent factions from subverting the common good. Subsequent history has demonstrated that Madisonian constitutional architecture, while necessary, is not sufficient for democratic government to operate in the interest of the people as a whole, rather than on behalf of a faction and its own interests. Instead, it is necessary to supplement Madisonian constitutional architecture with a well-designed electoral …

Originalism, Election Law, And Democratic Self-Government, Joshua S. Sellers

Florida Law Review

Originalism has a democracy problem. Among prevailing theories of constitutional interpretation—pragmatism, common-law constitutionalism, popular constitutionalism, and Elysian representation-reinforcement—originalism uniquely creates a legal environment in which antidemocracy is viable. That is, it uniquely imperils democratic structures, practices, and norms that are essential to modern democratic self-government. This fundamental flaw is most apparent when considering the relationship between election law (a conspicuously non-originalist area of law) and originalism. Accordingly, this Article uses election law as a heuristic for illustrating one of originalism’s central deficiencies. It is the first extended treatment of election law and originalism—a topic of heightened salience following the Supreme …

The Effect Of Finasteride On Parity Rates In Drosophila Melanogaster, Trey Bruno, Carly Turner, Michael Guildin, Carol Mitchell, Dominic Sandell, Alesha Fleming

Beyond: Undergraduate Research Journal

Finasteride has been used to treat male pattern baldness and benign prostate hyperplasia and could potentially treat female pattern baldness and polycystic ovary syndrome. The impact on reproduction in female patients who are taking or have taken finasteride is unknown. Using drosophila melanogaster as a model, this study was designed to investigate the impact of finasteride on female fly reproduction and their offspring. The female flies in this study will be fed dosage equivalents of 0.5 mg, 1 mg, and 5 mg of finasteride, along with a control group of females who consume no finasteride. The flies will be allowed …

Authenticity In Historical Fiction, Reaghan Sara-Anne Avery

Masters Theses

Authenticity is often debated in the field of literature. It’s an element that attests to an author’s credibility and a work’s originality, specifically the measure of an author’s genuine intent and the historical veracity of the work, including the genre of historical fiction. Authenticity can be defined in twofold terminology: those being the idealism and the factual, historically based evidence of the piece. Assessing a work’s authenticity by analyzing its believability and relatability is a three-part process that includes looking at the realistic dialogue, sensory and detailed language, and historical elements in a given text. The partial novel below entitled, …

A Missionary's Memoirs: Mongolia Revisited, Isaac Smith

Undergraduate Honors Theses

This is my story. It is a very personal story, but one that I want to share with others. Although it takes place predominantly in Mongolia, it is not merely a story about Mongolia, or even the Mongolian people. It is not really even a story about me. What is it then? It is a story about faith and love. It is an attempt to better understand how the gospel of Jesus Christ intricately fits into people’s lives all over the world—even in Mongolia. It is a compilation of essays, of memoirs, of my experiences. It is a story about …

Dna-Damaging Chemotherapy Reshapes The Immune Landscape Of The Heart, Ruijun He

Arts & Sciences Graduate Student Theses and Dissertations

Heart failure and ischemic heart disease represent the most common causes of death among cancer survivors. With the tremendous progress in last few decades that empowered early cancer diagnosis and treatment, the population of cancer survivors has been rapidly growing and by 2040, the number is projected to be 26 million. However, despite extensive studies on chemotherapies, there exists a limited understanding of how exposure to chemotherapy reagents impacts heart function in the long term. Moreover, while the roles of immune landscape in heart diseases have recently been revealed, how chemotherapy reagents influence the cardiac immune cells is poorly understood. …

Hierarchy Viz: A Visual Analytics Framework For Visualizing Hierarchical Data Using Machine Learning, Vinay Kumar Uppalapati

Theses and Dissertations

Automated visualization systems aim to generate visualizations directly from raw data with minimal user inputs. However, while existing systems focus on data visualizations mainly using line charts and scatter plots to explore the data patterns, they struggle with hierarchical data representation where data relationship is essential. Hierarchical visualization, crucial for understanding multi-level relationships, typically requires users to manually define hierarchies and have expertise in visualization tools to create meaningful representations. This makes the process complex, time-consuming, and reliant on domain knowledge. To address this, we propose HierarchyViz, an automated system that detects multiple hierarchies in raw datasets and generates intuitive …

Neil S. Braun, Dean Emeritus, Neil S. Braun

Oral History

Neil Braun, Dean Emeritus of the Pace University Lubin School of Business, talks about his life, career, and experiences as Dean, from the year 2010 to 2020. He also spoke about his initiation of the mentorship program, and its rewarding impact on students, as well as himself.

Seven Days With Coco (Stray Cat And War Refugee), Snjezana Marinkovic

Masters Theses

This thesis presents stories of those whose lives are governed by trauma, unfortunate life circumstances, and social pressure. It is a mixed form work that includes narrative nonfiction and poetry. It also utilizes some of the fiction techniques, such as setting, description, and inner point of view (e.g., seeing the world through the eyes of an unwanted animal).

Macrolide Antibiotic Mediated Cardiac Arrhythmias: Emerging Concepts And Clinical Implications, Fatima Iqbal, Alyssa Derouen, Robin Ren, Adam M. Kaye, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D. Kaye

Pacific Faculty Work

The macrolide class of antibiotics are widely utilized in clinical settings for a broad range of bacterial infections and have additional roles as immunomodulatory agents. Although efficacious with a good safety profile overall, they have been associated with prolongation of the QT interval and development of the polymorphic ventricular tachycardia, Torsades de pointes (TdP). In a 2020 scientific statement, the American Heart Association (AHA) classified azithromycin, clarithromycin and erythromycin as QT-prolonging drugs known to cause TdP and the online database, CredibleMeds, that maintains a list of drugs known to cause QT prolongation classifies these drugs as having an increased risk …

Medst 343w - Nonfiction Forms (8 Week Async Section), Ash Marinaccio

Open Educational Resources

In this course, we will explore how various forms of nonfiction storytelling represent reality and shape our understanding of the world. Over the semester, we will examine how “the real” is represented across different mediums, including theatre, film, photography, and literature. Through critical readings, case studies, creative exercises, and Brightspace discussions, we will examine the intricate interplay between truth, ethics, form, and authorship in documentary and nonfiction works.

The course is divided into five units. The first unit introduces foundational questions of ethics, authorship, and cultural responsibility in nonfiction storytelling. The following units focus on specific forms: documentary theatre, nonfiction …

Renovated Spaulding Hall Unveiled, Jeremy Gasowski

UNH Today Archive

No abstract provided.

The Not-So Wonderful World Of Disney: How Disney Films Usurp What Is In The Bible, Jacquelyn Irene Cortez

Doctoral Dissertations and Projects

Disney films are often chosen as entertainment for families and their main target audience is children. While many adults still choose to watch these films, there is a darker side to these films. A majority of these films depict magic and/or witchcraft in them. The ideologies of feminism and toxic masculinity are on display in many of their films. And finally, a lot of these films mock God and what is in the Bible. When looking at popular films such as The Little Mermaid and Frozen, these films are teaching children about magic and making deals with the devil. Disney’s …

Impacts Of Early Childhood Trauma On Later Emotional, Behavioral, Educational, And Social Abilities, Stacey Merrill

Doctoral Dissertations and Projects

Early childhood trauma has a long-lasting impact on individuals’ social interactions, mental health, academic skills, behaviors, and parenting skills for the future generations. Understanding how early interpersonal developmental trauma impacts an individual during adolescence can help providers and caregivers know how to help them become successful students and later adults. Helping individuals early in their development can prevent the cycle of abuse from continuing. Trauma informed care can help bridge the gap between those with and without known traumas. This study consisted of an interpretive phenomenological qualitative design using semi-structured interviews to understand the impact of early trauma on adolescence …

The Tumor Suppressor Hnrnpk Induces P53-Dependent Nucleolar Stress To Drive Ribosomopathies, Pedro Aguilar-Garrido, María Velasco-Estévez, Miguel Ángel Navarro-Aguadero, Álvaro Otero-Sobrino, Marta Ibáñez-Navarro, Miguel Ángel Marugal, María Hernández-Sánchez, Prerna Malaney, Ashley Rodriguez, Oscar Benitez, Xiaroui Zhang, Marisa Jl Aitken, Alejandra Ortiz-Ruiz, Diego Megías, Manuel Pérez, Gadea Mata, Jesús Gomez, Miguel Lafarga, Orlando Domínguez, Osvaldo Graña-Castro, Eduardo Caleiras, Pilar Ximénez-Embun, Marta Isasa, Paloma Jimena De Andres, Sandra Rodríguez-Perales, Raúl Torres-Ruiz, Enrique Revilla, Rosa María García-Martín, Daniel Azorín, Josune Zubicaray, Julián Sevilla, Oleksandra Sirozh, Vanesa Lafarga, Joaquín Martínez-López, Sean M Post, Miguel Gallardo

Faculty, Staff and Student Publications

The nucleolus is a membraneless organelle and an excellent stress sensor. Any changes in its architecture or composition lead to nucleolar stress, resulting in cell cycle arrest and interruption of ribosomal activity, critical factors in aging and cancer. In this study, we identified and described the pivotal role of the RNA-binding protein HNRNPK in ribosome and nucleolar dynamics. We developed an in vitro model of endogenous HNRNPK overexpression and an in vivo mouse model of ubiquitous HNRNPK overexpression. These models showed disruptions in translation as the HNRNPK overexpression caused alterations in the nucleolar structure, resulting in p53-dependent nucleolar stress, cell …

Using Microsoft Teams Class Notebook E-Portfolios As A Reflective Tool In Education For Sustainable Development Business Writing: Learners’ Perspectives, Mona Abdelfattah

Higher Learning Research Communications

Objective

This study investigates the efficacy of Microsoft Teams Class Notebook ePortfolios as a reflective tool in business writing courses. This study addresses gaps in the literature regarding ePortfolio use in business writing courses in F2F classes, focusing on student perceptions, its impact on writing skills, the convenience of the MS Teams Class Notebook, and how it fosters critical thinking regarding their learning which is one of the important goals of Education for sustainable development (ESD).

Methods

The iterative cross-sectional study was conducted over 13 weeks at a private college in Oman with 60 undergraduate students in two business writing …

The Colors Of Good And Evil: A Quantitative Study On The Effect Of Disney Animated Feature Films On Audience Color Association, Grace Mallory Hayes

Masters Theses

The purpose of this quantitative research study was to determine what impact Disney animated feature films have on audience color association. The problem is that Disney assigns colors to certain movie roles that are in contrast to what color theory posits or would assume. This study sought to determine if audiences that are highly saturated in Disney animated feature films receive a different message from colors than someone who does not regularly consume Disney films. This research examines the impact of Disney habitually assigning colors to characters in contrast to their traditional meaning on the emotional association of viewers through …

Olfactory Training: Reclaiming Our Wellbeing, Nathan Smetzer

Doctoral Dissertations and Projects

The connection between the sense of smell and memory offers a promising avenue for enhancing cognitive, emotional, and mental health, thereby contributing to overall wellbeing. This research explores how olfactory stimuli relate to memory and emotion, aiming to expand understanding of the effects of scent-based interventions on mental health. Utilizing a 12-week longitudinal phenomenological approach with experimental components, the study engaged seven participants in a regimen of olfactory training twice daily. Participants used essential oils—citrus, cloves, eucalyptus, and rose—applied to cotton and kept in sealed containers, along with a pen and daily planner. Data were gathered through recurring qualitative interviews …

Beyond The Genome: The Racialized Exposome, Flourishing, And Stress Biology In African Americans, A Non-Exhaustive Review, Enye Washington

University Honors Theses

Racial health disparities remain an enduring challenge in the United States, disproportionately impacting African American communities through higher rates of chronic disease and premature mortality. This non-exhaustive literature explores how the racialized exposome - a term denoting the totality of social, environmental, and structural stressors rooted in systemic racism - biologically embeds itself via stress-responsive pathways. Specifically, it examines the interaction between racial stress, flourishing, and key biological markers, including allostatic load and telomere length, considering the gut-brain axis. The review highlights robust evidence that chronic exposure to racial discrimination and structural adversity contributes to multisystem dysregulation and accelerated cellular …

A Qualitative Case Study On Nature Relatedness In Advanced Alpinists And Members Of Subsistence Communities, Devon Martin

University Honors Theses

In light of the current possibility of climate disaster and ecological destruction, a branch of psychology has formed to investigate the human relationship with nature. Scaled surveys have been created to gauge nature relatedness with the hope that this construct might help predict environmental awareness and action towards environmental change. This undergraduate thesis aims to explore the concept of connection to nature through a detailed case study on two participants who are both advanced alpinists (high risk mountain recreationalists) and members of subsistence communities (procuring food directly from the environment). The participants were given scaled surveys of nature relatedness and …

In Vivo Direct Lentiviral Gene Therapy Improves Disease Pathology In A Mucopolysaccharidosis Iva Murine Model, Betul Celik, Estera Rintz, Shaukat Khan, Andrés F. Leal, Fnu Nidhi, Shunji Tomatsu

Department of Pediatrics Faculty Papers

Mucopolysaccharidosis IVA (MPS IVA) is an autosomal recessive disorder that causes the accumulation of keratan sulfate (KS) and chondroitin-6-sulfate in bone and cartilage. This results in progressive skeletal dysplasia, with no effective treatment available. Our study hypothesized that direct lentiviral vector (LV) gene therapy could produce active enzymes from transduced cells, impacting bone and cartilage lesions in MPS IVA. We developed LVs carrying the GALNS gene under three promoters: ubiquitous (CBh), collagen type II (COL2A1), and Mac-1 integrin subunit (CD11b). At the newborn stage and 4 weeks, Galns-knockout mice received intravenous injections at different doses (5 × 10^{9 …}

Integrating Faith And Academic Administration, Derek Schuurman

University Faculty Publications and Creative Works

No abstract provided.

Vitamin D And Cognition: Demographic Disparities In Memory Recall And Word Intrusion In A Multiethnic Cohort, Juan Lopez-Alvarenga, Isabel Omaña-Guzmán, Oscar Rosas-Carrasco, Jose E. Cavazos, Michael C. Mahaney, Gladys E. Maestre

School of Medicine Publications

Background

Vitamin D3 is essential for calcium metabolism and exerts pleiotropic effects, including neuroprotective activities in cognition. Its insufficiency has been linked to dementia, Alzheimer's disease, and cognitive impairments. The association between vitamin D3 and particular cognitive functions, including memory recall and word intrusion, remains imprecise, particularly among diverse ethnic and socioeconomic groups.

Objective

To examine the relationship between vitamin D3 levels with memory recall and word intrusion in individuals aged 60 and above, emphasizing demographic differences.

Methods

Data was collected from 2759 individuals in the NHANES 2011–2014 surveys. Cognitive performance was evaluated with the CERAD Word Learning, Animal Fluency, …