Digital Commons Network^™

Harboring Change: Legacy Contamination, Plant-Metal Dynamics, And The Fate Of A Boston Marsh, Emma Brooks

Graduate Masters Theses

Coastal wetlands within the Boston Harbor watershed provide numerous ecosystem services and community benefits but are challenged by anthropogenic influence including a legacy of pollution and increasing mean sea level. In this thesis, I will consider the historic and present sources of contamination in Boston Harbor, the role an individual salt marsh species (Salicornia depressa) plays in the movement of heavy metals, and how projected sea level rise and urbanization may affect future marsh viability. These complex issues are explored through a case study of Pattens Cove, a 9.6-acre parcel of state-managed land in Dorchester, MA home to …

Methods Of Measuring C19mc Mirna In A Post-Natal Tissue And Uses Thereof, Hana Totary-Jain, Ezinne Frances Mong

USF Patents

Provided herein are methods of measuring C19MC miRNA amount and/or expression in a post-natal cell and/or tissue. Provided herein are methods of measuring CpG methylation of the upstream C19MC miRNA promoter region in a post-natal cell and/or tissue. Also provided herein are methods of treating a cell, population thereof, and/or a subject in need thereof by administering a C19MC miRNA inhibitor or CRISPR to suppress the expression of specific miRNA within the C19MC or the entire C19MC cluster, population thereof, and/or the subject in need thereof.

The Hollywood Reporter Names Four Cardozo Alumni To Top Entertainment Attorney Lists, Benjamin N. Cardozo School Of Law

Cardozo Law News Archive

Four Cardozo alumni were recognized by The Hollywood Reporter in its 2025 lists of top entertainment attorneys. Sasha Levites ’11 and Rachel Strom ’06 were named among New York’s Biggest Entertainment Attorneys, while Marc H. Simon ’01 and Gregory Slewett ’02 were included in Hollywood’s Top 100 Attorneys. Their achievements highlight Cardozo’s national strength in Intellectual Property and Entertainment Law, with alumni shaping major film, television, media, and digital industries.

Ldl Receptor-Mediated Endocytosis Of Escherichia Coli Α-Hemolysin Mediates Renal Epithelial Toxicity, Hunter W Kuhn, Madeleine R Smither, Rachel J Jin, Christina A Collins, Hongming Ma, Jason Sina, Joseph P Gaut, Michael S Diamond, David A Hunstad

2020-Current year OA Pubs

The α-hemolysin (HlyA) of uropathogenic

Sars-Cov-2 Nsp15 Enhances Viral Virulence By Subverting Host Antiviral Defenses, Allen Caobi, Tamarand L Darling, Adrianus C M Boon, Et Al.

2020-Current year OA Pubs

SARS-CoV-2 encodes numerous virulence factors, yet their precise mechanisms of action remain unknown. We provide evidence that the SARS-CoV-2 nonstructural protein 15 (nsp15) enhances viral virulence by suppressing the production of viral double-stranded (dsRNA), a potent inducer of antiviral signaling. The viral variants lacking nsp15 endoribonuclease activity elicited higher innate immune responses and exhibited reduced replication in human stem cell-derived lung alveolar type II epithelial cells, as well as in the lungs of infected hamsters. Consistently, these variants caused significantly less weight loss and mortality compared to wild-type (WT) virus in K18-hACE2 mice. Mechanistically, the cells infected with nsp15 mutants …

What Is A Mineral In The Green Energy Age?, Jonathan J. Rose

LSU Journal of Energy Law and Resources

No abstract provided.

Usufruct Issues In Mineral Leasing And Ccus Agreements, Margaret Patton

LSU Journal of Energy Law and Resources

No abstract provided.

If You Give A Forced Labor System A Cookie: How Congress Can Enforce Conservation And Human Rights Laws In The Palm Oil Industry Through A Lacey Act Approach, Marissa Torres

LSU Journal of Energy Law and Resources

No abstract provided.

Energizing The Sunshine State: Navigating Florida’S Transition To Renewable Energy, Delaney Reynolds

LSU Journal of Energy Law and Resources

No abstract provided.

Atpase Level In Iraqi Diabetic Patients With And Without Diabetic Kidney Disease, Reham Khuldon Ibrahim, Kadhim K. Ghudhaib, Ali Abdulmajid Dyab Allawi

Baghdad Science Journal

Complications of diabetes have become one of the main problems that diabetics suffer from, especially during long periods. One of these complications is diabetic nephropathy, as both glomeruli and tubules are exposed to fibrosis due to diabetes. Recent years have witnessed great interest by researchers regarding diabetic nephropathy. This study aimed to determine the level of ATPase and some of the relevant biochemical factors in patients with diabetes and diabetic nephropathy compared with healthy controls. The study included 120 male and female (60 male and 60 female) ranging in age (30-65) years old. Ninety patients with type 2 diabetes are …

Feed It To The Ocean: The Federal Approach To Decommissioning In Alaska Native Climate Adaptation Projects, Sophia Tidler

Alaska Law Review

This Note calls on the Council on Environmental Quality (CEQ) to issue guidance clarifying that concurrent decommissioning is an in-scope “connected action” under the National Environmental Policy Act for relocation, managed retreat, and protect-in-place projects aimed at replacing infrastructure in environmentally threatened Alaska Native communities. In 2018, the Denali Commission completed the Final Environmental Impact Statement for Alaska’s first community-driven village relocation of the millennium, facilitating construction of essential infrastructure at Mertarvik, the relocation site for the village of Newtok. However, the Denali Commission chose to exclude a full-scale decommissioning plan for Newtok’s existing infrastructure. Today, more than seventy-three Alaska …

New Hampshire’S House Environment And Agriculture Committee Visits Unh, Mark Wanner

UNH Today Archive

No abstract provided.

Integrative Taxonomy Confirms The Synonymy Of Three Springsnail Species (Hydrobiidae: Pyrgulopsis), Kathryn E. Perez, Megan Solis, Michelle Flores, Chanté Lundskog

School of Integrative Biological & Chemical Sciences Faculty Publications

The small, spring-dwelling snails, Pyrgulopsis Call & Pilsbry, 1886, form a diverse radiation in Western North America. In this study, we examine the validity of three species of Pyrgulopsis, Pyrgulopsis pilsbryana (Baily & Baily, 1952), P. nonaria Hershler, 1998, and P. transversa Hershler, 1998. These three species of Pyrgulopsis are found primarily in Utah, with ranges extending into Idaho, Wyoming, and Nevada. They were originally diagnosed primarily on the number and position of penial glands, but subsequent examination with mitochondrial DNA data suggested they should be synonymized. Here, we incorporate additional mitochondrial and nuclear DNA data, increased geographic sampling, …

Potential Epigenetic Impacts Of Phytochemicals On Ruminant Health And Production: Connecting Lines Of Evidence, Sebastian P. Schreiber, Juan Villalba, Mirella L. Meyer-Ficca

Wildland Resources Student Research

The once mysterious “dark matter of nutrition”, comprising countless plant derived secondary compounds, also known as phytochemicals, is now understood to have significant and wide-ranging effects on consumers, including myriad health benefits in humans and livestock. The selective consumption of phytochemically rich and diverse plants, in appropriate doses, by ruminants represents an adaptive means of therapeutic and prophylactic self-medication. Due to their chemical structure, phytochemicals have long been recognized as antioxidants. However, the mechanisms that underlie numerous additional phytochemical-based health benefits are generally less understood. These effects (i.e., anti-inflammatory, immunomodulatory, and anticarcinogenic effects) are likely related to epigenetic processes. Evidence …

A Community-Based Study To Investigate Persistent Ambient Odors In Childs Park, Fl, Gennaro Saliceto

USF Tampa Graduate Theses and Dissertations

For many years, residents in Childs Park, Saint Petersburg, Florida, have reported unpleasant odors. Although there have been prior efforts to address the issue, the odors continue to be a concern for the community, who worry about possible health implications. This research aimed to equip residents with information to address the issue by identifying the presence of airborne pollutants that generate odors, quantifying the concentrations of toxic organic pollutants, and exploring the sources and environmental conditions that contribute to odors and their perception.

To accomplish these aims, the study utilized different methods. First, two walking measurement campaigns were conducted to …

Identification Of Hypoxia-Inducible Factor Hif1a As A Therapeutic Target During Sars-Cov-2-Associated Lung Injury, Bentley Bobrow, Samuel D Luber, Paul Potnuru, Katherine Figarella, Jieun Kim, Yanyu Wang, In Hyuk Bang, David Robinson, Paulina B Sergot, Steven K Burke, Tingting Mills, Constanza De Dios, Robert Suchting, George W Williams, Adit A Ginde, Yafen Liang, Hongfang Liu, Charles Green, Marie-Francoise Doursout, Alparslan Turan, Daniel I Sessler, Xiaoyi Yuan, Holger K Eltzschig

Faculty, Staff and Student Publications

Hypoxia-inducible factors (HIFs) promote lung protection and pathogen eradication during acute lung injury. We therefore tested the theory that pharmacologic stabilization of HIFs dampens lung injury during SARS-CoV-2 pneumonia. Initial studies in murine SARS-CoV-2 models showed improved outcomes after treatment with the FDA-approved HIF-stabilizer vadadustat. Subsequent studies in genetic models implicated alveolar-expressed Hif1a in mediating lung protection. Therefore, we performed a randomized, double-blinded, multicenter phase 2 trial in patients admitted for SARS-CoV-2 infection and concomitant hypoxia (SpO2 ≤ 94%). Patients (n=448) were randomized to oral vadadustat (900 mg/day) or placebo for up to 14 days. Safety events were similar between …

Synthesis, Antibacterial Evaluation, And Prediction Of The Ability Of Corrosion Inhibition By Density Functional Theory Of Azo-Dyes Of Folic Acid, Athra G. Sager, Jawad Kadhim Abaies, Aseel F. Abdullah

Baghdad Science Journal

In this study, new folic acid (B9) derivatives (a–d) were synthesized by reacting diazonium salt (of folic acid) with different aromatic compounds including 1-naphthol, 2-naphthol, pyrocatechol, or resorcinol. One of Schiff bases (I) was prepared by reacting folic acid with 4-amino benzaldehyde. Then, azo compound (e) was synthesized by coupling Schiff base with 1-naphthol. The new azo compounds (a–e) were identified by FTIR, ¹HNMR spectroscopy, and by measurements of some physical properties. The current work investigated the physical characteristics of compounds (a–e) in order to select the best corrosion inhibitor. 6-311G⁺/(d, p) base set and Density Functional …

Synthesis, Characterization And Studying Biological Activity Of New Schiff Base Compounds Derived From “N-[(4-Hydroxy-3-Methoxyphenyl) Methyl]-8-Methyl-(E)-6-Nonenamide”, Huda Salman Hassan, Sana Hitur Awad

Baghdad Science Journal

This research includes synthesizing new bis-Schiff bases linked to“N-[(4-hydroxy-3-methoxyphenyl) methyl]-8-methyl-(E)-6-nonenamide” derivatives. This work involved ring opening of phathalic anhydride by hydroxyl groups in “N-[(4-hydroxy-3-methoxyphenyl) methyl]-8-methyl-(E)-6-nonenamide” then, they were reacted with thiourea to synthesize Schiff bases by the reaction of different aldehydes. The first step involved the condensation reaction between “N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-(E)-6-nonenamide” (H) and phthalic anhydride to produce(H1). In the second step, compound H1 was reacted with one mol of thiourea to produce maliamic compound (H2). The third step involved the preparing of Schiff bases derivatives, by the reaction of (H2) with different aldehyde to produce compounds (H3 and H4). These compounds …

Synthesis, Characterization And Studying Mass Spectra And Thermal Analysis For Complexes Of Some Metal Ions And Determining Their Activity As Antioxidants, Fatimah Al-Zahraa Sh. H, Abbas Ali Salih Al-Hamdani

Baghdad Science Journal

The new azo dye was prepared from the reaction of the diazonium salt derived from 3-aminophenol with 2-hydroxyquinoline, then it was used to prepare a series of complexes with the chlorides of cobalt, chromium, copper, nickel, platinum, palladium and ammonium molybdate. The ligand was identified by a proton and carbon nuclear magnetic resonance spectroscopy, and the compounds were collected. The prepared materials were subjected to infrared, ultraviolet-visible, and mass spectrometry, as well as thermogravimetric analysis, differential calorimetry, and elemental analysis. Conductivity, magnetic susceptibility, metal content, and chlorine content of the complexes were also measured. The results showed that the ligand …

Utilizing An Atomic Force Microscopy With Continuous Flow Injection Analysis Using Nag-4(Sources)X3 With Three Solar Cells (Nag-4sx3-3d) Analyzer For Studying The Surface Morphology Of The Precipitate Of The Cyproheptadine-Hcl And Loratadine, Bakr Sadiq Mohammed, Nagham Shakir Turkey

Baghdad Science Journal

The objective of this study is to describe surface morphology using Continuous Flow Injection Analysis CFIA, Atomic Force Microscopy AFM, and the homemade NAG-4(sources)x3 with three solar cell Analyzer NAG-4SX3-3D analyzer. Using a novel method for determining both drugs via reaction of both drugs, the study aims to determine the roughness parameters of (white precipitate of loratadine with sodium nitroprusside and yellow precipitate of cyproheptadine hydrochloride with 3,5-dinitro salicylic acid) for the AFM sample. The main advantage of the proposed technique is its ability to compute the amount of nanoparticles that can fill the empty surface area. Starting with the …

Synthesis And Antioxidant Evaluation Of Urea, Carbamate, And Triazole Derivatives Of (2-(6-Methoxynaphthalen-2-Yl) Propanoyl) Glycinoyl Azide, Jihan A. Mustafa, Huda A. Basheer, Parween H. Saleem

Baghdad Science Journal

In this study, a novel series of compounds, derived from the drug naproxen, was synthesized, this series includes carbamates, ureas, semicarbazides, and 1,2,4-triazole derivatives, and the synthesis was achieved through a multi-step synthetic approach. Initially, hydrazide (1) was prepared by reacting naproxen amino acid ester with hydrazine hydrate, followed by its conversion to naproxen glycine azide (2) through treatment with sodium nitrite in hydrochloric acid. Azide (2) was then subjected to thermal decomposition via Curtius rearrangement to yield isocyanate (3). Isocyanate (3) was subsequently reacted with various reagents, such as water, alcohol, amine, concentrated hydrochloric acid, hydrazine, and naproxen hydrazide, …

Synthesis And Biological Study Of Schiff–Mannich Base Derived From 2-Mercaptobenzimidazole As Chelated Tridentate Ligand With Some Transition Metal Ions Complexes, Thuraya Q. Sabah, Shaymaa R. Baqer

Baghdad Science Journal

To prepare a new ligand, many compounds were used to synthesize Schiff-Mannich base, such as isatin, Para chloro Aniline, 2-mercaptobenzimidazole and indole. The resulting compound 1-((2-((1H-indol-1-ylthio)-1H-benzo[d]imidazol-1-yl)methyl)-3-(4-chlorophenylimino)indolin-2-one (L). (L) was used to create a series of metal ion complexes with Co (II), Ni (II), Cu (II), Pd (II), Pt (IV), and Au (III). C.H.N.S., FTIR, mass spectra UV-ViS, 1H-NMR, 13CNMR, magnetic moment, and molar conductivity were used to characterize all of these compounds. Except for the palladium(II) and gold(III) complexes, all of the produced complexes had an octahedral geometry, according to the data. The antibacterial activity of the produced compounds was …

Photocatalytic Degradation Of Acid Yellow 25 Using Nanoparticle Tio2 Mediated Petai Pod Extract, Anthoni Batahan Aritonang, Reza Audina Putri, Vivi Sisca, Mohammad Jihad Madiabu, Khoiriah Khoiriah

Baghdad Science Journal

Nanotechnology has significant advantages over traditional methods for degrading dyes. Plant-based nanoparticles were generated apart from other biomaterials. This work employed a green sol-gel approach to prepare titanium dioxide nanoparticles by using Petai (Parkia speciosa) peel extract. The produced TiO₂ was analyzed by XRD, UV-DRS, FE-SEM, FTIR, Raman, zeta, and nanoparticle size analysis. PP-TiO₂ nanoparticles having a tetragonal anatase phase, spherical, stable particles, and a small particle size (16–22 nm) were successfully produced. When exposed to UV light, the nanoparticles displayed strong photocatalytic activity, eliminating Acid Yellow 25 in less than 120 minutes. This work demonstrates …

The Effect Of Dbd-Non Thermal Plasma On Oxidative Stress And Tac In Patients With Hcv Infection, Salima K. Ahmed, Salwa H. N. Al- Rubae’I, Hamid H. Murbat, Mazin R. Mohammed

Baghdad Science Journal

Non-thermal plasma (NTP) is a processing technique that is widely-spread in different biological and medical application which stimulates or inhibits cellular processes through releasing reactive oxygen and nitrogen species (ROS and RNS, respectively) in biological systems. In this study, it was investigated that the impact of NTP on oxidative stress and antioxidant capacity markers, as well as the effect of NTP on the copy number of Hepatitis C virus (HCV RNA). Dielectric barrier discharge (DBD) plasma was used to generate the NTP. The results showed that the exposure of HCV specimen to NTP causes oxidative stress, RNA damage, Protein denaturation, …

Btp2 Restricts Tulane Virus And Human Norovirus Replication Independent Of Store-Operated Calcium Entry, Francesca J Scribano, J Thomas Gebert, Kristen A Engevik, Nicole M Hayes, Jorge Villanueva, Son Pham, Soni Kaundal, Janam J Dave, B V Venkataram Prasad, Mary K Estes, Sasirekha Ramani, Joseph M Hyser

Faculty, Staff and Students Publications

Human norovirus is the leading cause of viral gastroenteritis across all age groups. While there is a need for human norovirus antivirals, therapeutic development has been hindered by a lack of cell culture systems and animal models of infection. Surrogate viruses, such as Tulane virus (TV), have provided tractable systems to screen potential antiviral compounds. Our previous work demonstrated that TV encodes a viral ion channel, which dysregulates cytosolic calcium signaling. We set out to investigate whether host pathways triggered by viral ion channel activity, including store-operated calcium entry (SOCE), play a role in virus replication. Using pharmacologic inhibitors and …

Crashes And Injuries On Rural Roads In Alaska - Toward A Better Understanding Of Rural Safety Issues Through Linked Data And Environmental Factors Task B: Environmental And Geometric Safety Factors Of Rural Crashes, Vinod Vasudevan

CSET Project Reports

Alaska experiences extreme weather and driving conditions compared to many other locations in the United States. For example, during summer, most traffic activity occurs in daylight, whereas in winter months, the majority of traffic activity occurs in the dark. Similarly, driving conditions change drastically across seasons. During winter, heavy snow and extremely cold temperatures provide challenges for drivers. These conditions lead to safety concerns such as noticeable changes in daylight hours, peak traffic activities in dark hours, and reduced friction values due to snow and ice. Another challenge is the sun's position above the horizon throughout the year, especially during …

Global Mitophagy Inhibition Via Bnip3 Ablation Is Not Sufficient To Alleviate Skeletal Muscle Impairments In Male And Female Tumor-Bearing Mice, Francielly Morena, Ana Regina Cabrera, Toby L. Chambers, Pietier J. Koopmans, Seongkyun Lim, Stavroula Tsitanou, Sabin Khadgi, Calvin Peterson, Eleanor R. Schrems, Ruqaiza Muhyudin, Sepideh Shakeri, Kevin Zhao, Devan Mishra, Tyrone Washington, Kevin A. Murach, Nicholas P. Greene

Health, Human Performance and Recreation Faculty Publications and Presentations

Cancer cachexia (CC) is marked by severe skeletal muscle loss and dysfunction, associated with mitochondrial degeneration. Our previous studies showed induction of the mitophagy marker BNIP3 3-wk post-Lewis lung carcinoma (LLC) induction. We hypothesize that excessive mitophagy contributes to muscle wasting in CC. To test this, we used a Bnip3 knockout (KO) mouse model with LLC-induced CC to assess its impact on muscle outcomes. Eight-wk-old male and female mice were injected with 1 x 10(6) LLC cells or PBS (sham controls). After 4 wk, we assessed muscle function through dorsiflexor electrophysiology, muscle protein synthesis via deuterium oxide labeling, and mitochondrial …

How The Immediate Physical Environment Affects The Non-Physical Aspect Of Health, Katryn Noelle E. Valeriano

Budhi: A Journal of Ideas and Culture

Human health has been closely intertwined with environmental health. By the term “environment,” I refer not only to nature or relationships found in an ecosystem but also to the immediate physical milieu of an individual or what is termed as “personal space.” Before the pandemic, the notion of personal space was more fluid and receptive due to the ease one had in “re-framing” the environment and reorienting oneself. However, during the pandemic, the personal space of humans was restricted in so many ways through lockdowns and various forms of isolation. This article intends to re-interpret concepts, such as of “physical …

Using Lrr Standard Deviation As A Genotype Quality Control Measure And Its Downstream Effect On Cnv Calling., Adam Dunne

ORBioM (Open Research BioSciences Meeting)

Background:

Log R Ratio (LRR) is a genotype intensity measurement returned alongside routine genotype results and used to detect structural variation in the genome known as copy number variation (CNVs). Although LRR standard deviation (SD) is commonly applied as a quality control measure in CNV studies, limited research has explored its effect on genotype quality and the potential impact on CNV calling.

Methods:

A total of 720,152 genotypes were available on 716,234 cattle. Among these were 1,044 cattle that had duplicate genotype samples where one sample was considered gold standard (LRR SD < 0.3, Call Rate ≥ 0.95). Genotype concordance was calculated for all duplicates. PennCNV was used to call CNVs and concordance among CNV calls per duplicate animal was determined using the Jaccard index.

Results:

Across all 720,152 cattle samples, the mean …

Transunion, Vermont Agency, And Statutory Damages Under Article Iii, Randy Beck

Florida Law Review

The Supreme Court concluded in TransUnion LLC v. Ramirez that a plaintiff may not sue to collect statutory damages under a statute such as the Fair Credit Reporting Act simply because the defendant violated a right Congress conferred on the plaintiff. Article III instead requires the plaintiff to show that the statutory violation resulted in a “concrete” injury with “a ‘close relationship’ to a harm ‘traditionally’ recognized as providing a basis for a lawsuit in American courts.” Under the majority’s reading of Article III, “an injury in law is not an injury in fact.”

The TransUnion Court made no effort …