Digital Commons Network^™

Melodramatic Joy In Ibrahim Nasrallah’S Trilogy Of The Bells, Adam V. Spanos

CLCWeb: Comparative Literature and Culture

This essay argues that absurdist humor, so often theorized as a challenge to metaphysical and identitarian claims, in fact supports such claims within the context of anticolonial nationalist melodrama. In his Trilogy of the Bells [2019], Palestinian writer Ibrahim Nasrallah uses the conventions of melodrama to make an epistemological claim specific to Palestinian experience. Confronting a regime that has been largely successful in determining the internationally accepted common sense about the conflict, Nasrallah aims to present the external world with a narrative of Palestinian history, experience, and aspirations. The Manichean distinctions, spectacular displays of pathos, and manifestations of suppressed secrets …

Spartanburg County School Integration Project: Bob Coleman And John Keith Interview, Bob Coleman, John Keith, Clayton Whisnant, Dallas Green, Wade Toth

Oral History Interviews

Spartanburg County School Integration Project

Narrators: Bob Coleman (BC) and John Keith (JK)

Interviewers: Dr. Clayton Whisnant (CW)

Dallas Green (DG) and Wade Toth (WT)

at Wofford College

July 21, 2025

Creating A Legacy: Dipping Into The Business Of Selling Ink Artwork, Janelle Sather

Strategic Communication Master of Arts Thesis Projects

Peaceful Wisconsin LLC is a dip pen ink art business in Eau Claire, Wisconsin. This project uses research and analysis to uncover strategic and creative solutions to address the business’s core problem of customers not having a way to purchase the company’s artwork. A review of applied research was conducted, which included residential demographic information, art sale methods and statistics, Twitch viewership data, and the company’s financial statements. Key findings showed there is a strong potential market for selling art, and the company can become profitable with minimal sales. The company has never conducted research or a strategic analysis of …

A Simple Action Reduces High-Fat Diet Intake And Obesity In Mice, M. R. Barrett, Y. Pan, C. L. Murrell, E. O. Karolczak, J. Wang, L. Z. Fang, J. M. Thompson, Y.-H. Chuang, E. Casey, J. E. Czarny, W. L. So, A. Reichenbach, R. Stark, H. Taghipourbibalan, S. R. Penna, K. B. Mccullough, S. R. Westbrook, G. C. Basu, B. Matikainen-Ankney, V. A. Cazares, K. Delevich, Wambura C. Fobbs, S. E. Maloney, A. S. Hickey, J. E. Mccutcheon, Z. B. Andrews, M. C. Creed, M. J. Krashes, A. V. Kravitz

Psychology Faculty Works

Diets that are high in fat cause overeating and weight gain in multiple species of animals, suggesting that high dietary fat is sufficient to cause obesity. However, high-fat diets are typically provided freely to animals in obesity experiments, so it remains unclear whether high-fat diets would still cause obesity if these diets required more effort to obtain. We hypothesized that unrestricted access to high-fat diets is important for these diets to induce overeating and that requiring mice to perform small amounts of work to obtain a high-fat diet would reduce calorie intake and associated weight gain. To test this hypothesis, …

Ethical Implications Of Being A Holobiont, Scott F. Gilbert

Biology Faculty Works

Developmental plasticity and holobiont theory have undermined the normative concepts of biological individuality. However, such traditional ideas of biological individuality have helped define and support Western ethical views into the 21st century. Guided by some of the ethical formulae of Simone Weil, Hans Jonas, and Alastair MacIntyre, this essay attempts to outline some possible trajectories for an ethics that is bounded by these new biological paradigms of environmental agency. Specifically, the ecological developmental biology concepts of plasticity and holobiont theory permit the “ethics of attention” to focus on the partnerships of living beings. Highlighting environmentally integrated life cycles and their …

Rethinking Ohio Mandated Reporting For Child Neglect, Stephanie L. Ash

Et Cetera

This article briefly outlines the history and harm of family separation, reviews applicable federal and Ohio laws concerning child neglect and screening guidelines for investigation, and examines the social justice implications of rethinking mandated reporting requirements and implementing alternatives to protect children from systemic oppression and violence from the family policing system.

The Effect Of Tranexamic Acid On Blood Coagulation In Primary Total Hip Arthroplasty Using Rotational Thromboelastometry: A Randomized Controlled Trial, Uzung Yoon, David Beausang, Elia Elia, Marc Torjman, Jeffrey Mojica, James J. Purtill, David Nazarian, P. Maxwell Courtney, Yoogoo Kang

Department of Anesthesiology Faculty Papers

BACKGROUND: Tranexamic acid (TXA), is commonly administered prophylactically to reduce blood loss in patients undergoing total hip arthroplasty (THA). However, its effect has never been studied. We hypothesized that no difference exists in the degree of fibrinolysis and blood loss between patients receiving prophylactic TXA and placebo.

METHODS: This double-blinded randomized-controlled trial included 50 patients undergoing primary THA in 2021-2023. Clinicaltrials.gov (NCT03897621). Rotational-thromboelastometry (ROTEM) were performed to test blood coagulability using non citrated whole blood (NATEM) and blood treated with TXA (T-APTEM). The intervention group received TXA intravenously. The placebo group received 0.9% sodium chloride solution. The primary outcome measure …

From Glory To Glory: The Analogy Of Being In The Thought Of Karl Barth And Hans Urs Von Balthasar, Philip Micele

Seton Hall University Dissertations and Theses (ETDs)

In response to Karl Barth’s rejection of the analogia entis as “the invention of the Antichrist,” Erich Przywara insists that the great Protestant theologian’s criticisms are essentially of no avail, “because for him this biblical Christianity came, in fact, to assume the shape of a system of ‘ever greater dissimilarity,’ which is to say it fell under the spell of the very analogy he sought to flee.”[1] Przywara further stresses that “it is precisely in the analogy, understood as the ‘analogy of ever greater dissimilarity,’ that God is mighty and declares himself – the God who, ‘if you comprehend …

A Comprehensive Deep Learning System With Mgrf Modeling For Predicting Breast Cancer Response To Neoadjuvant Chemotherapy, Ahmed Sharafeldeen, Fatma Taher, Norah Saleh Alghamdi, Eman Alnaghy, Reham Alghandour, Khadiga M. Ali, Sameh Shamaa, Abdelrahman Gamal, Mohammed Ghazal, Sohail Contractor, Ayman El-Baz

All Works

Accurate prediction of breast cancer (BC) response to neoadjuvant chemotherapy (NAC) is critical for tailoring treatment strategies and improving patient outcomes. This study introduces a novel deep learning-based framework that integrates multi-parametric magnetic resonance imaging (MRI) (i.e., T1, T2, STIR, and DWI), along with clinical and molecular subtype markers, to classify tumor response into pathological complete response (pCR), partial response (PR), and stable disease (SD). First, tumor regions are delineated across MRI modalities and then modeled using a translation-invariant Markov-Gibbs random field (MGRF) with analytical parameter estimation to capture modality-specific spatial appearance patterns correlated with NAC response. Subsequently, diffusion-weighted MRI …

Monitoring The Kinetic Evolution Of Mesenchymal Stem Cell Differentiation Using Raman Microspectroscopy, Francesca Ravera, Esen Efeoglu, Hugh J Byrne

Research Outputs: 2025-Present

Raman microspectroscopy (RMS) offers a powerful, non-destructive approach for in situ monitoring of dynamic biochemical processes within cells. However, the ability to reliably data-mine the spectroscopic signatures and their evolution and extract meaningful information can be challenging. Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS) regression analysis is a powerful chemometric technique that can potentially address this challenge by deconvoluting the spectra into individual component spectra, each representing a specific biochemical species, and regressing the solutions against kinetic constraints. In this study, MCR-ALS analysis was performed on spectral data of differentiation process of mesenchymal stem cells into chondrocytes, carried out on two …

We Are Tectonic! A Queer Geophysics For Intra-Solidarities And Resisting The Cloud Regime, Helen Pritchard, Femke Snelting, Seda Gürses, Jara Rocha, Miriyam Aouragh

School of Art, Design and Architecture

This paper analyses how Big Tech and global consultancy firms are asserting control over carbon removal certification and governance through infrastructure solutions and technical standards. We argue that defining gaps in the underground constitutes a global takeover of material sovereignty, encompassing both knowledge and geological formations. We unearth Big Tech’s strategies of infra-solutionism to demonstrate, drawing on the work of inhuman geographer Kathryn Yusoff, how this takeover reinforces geological grammars and essentialises racialised and sexualised categories that disconnect us from the Earth. Drawing on queer poetry together with work of Marxist agronomist Amílcal Cabral we advocate for resistance to dominant …

Scorpions Of The Horn Of Africa (Arachnida: Scorpiones). Part Xl. Barbaracurus Lowei Sp. N. From Ethiopia (Buthidae), František Kovařík, Hassan Sh A. Elmi

Euscorpius

Barbaracurus lowei sp. n. from Ethiopia is described and compared with other species of the genus, fully complemented with color photos of specimens of both sexes of the new species, as well as of their habitat. Included is a key for Barbaracurus and a map of the distribution of the genus in the Arabian Peninsula and the Horn of Africa.

Liposome-Encapsulated Antibiotics For The Therapy Of Mycobacterial Infections †, Metin Yıldırım, Nejat Düzgüneş

Pacific Faculty Work

About a quarter of the world’s population is infected with Mycobacterium tuberculosis. Growing antibiotic resistance by this microorganism is a major problem in the therapy of the disease. M. avium-M. intracellulare that emerged as a major opportunistic infection of HIV/AIDS continues to afflict immunocompromised individuals. We describe the use of liposome-encapsulated antibiotics in the experimental and clinical therapy of mycobacterial infections, as well as recent experimental liposomal vaccines against tuberculosis. Liposome-mediated intravenous or inhalational delivery of antibiotics enhances the antibacterial effects of the drugs, particularly for infections of resident macrophages, where the liposomes are passively targeted. Despite experimental successes of …

Potential Biological And Genetic Links Between Dementia And Osteoporosis: A Scoping Review, Abayomi N Ogunwale, Paul E Schulz, Jude K Des Bordes, Florent Elefteriou, Nahid J Rianon

Faculty, Staff and Students Publications

Background: The biological mediators for the epidemiologic overlap between osteoporosis and dementia are unclear. We undertook a scoping review of clinical studies to identify genetic and biological factors linked with these degenerative conditions, exploring the mechanisms and pathways connecting both conditions.

Methods: Studies selected (1) involved clinical research investigating genetic factors or biomarkers associated with dementia or osteoporosis, and (2) were published in English in a peer-reviewed journal between July 1993 and March 2025. We searched Medline Ovid, Embase, PsycINFO, the Cochrane Library, the Web of Science databases, Google Scholar, and the reference lists of studies following the guidelines for …

Dietary Nitrogen And Its Role In The Gut Microbiome And Inflammatory Bowel Disease: A Narrative Review, Matthew Herrera, Lauri O. Byerley

School of Medicine Faculty Publications

In recent years, gut microbiota has emerged as a critical regulator of gastrointestinal health and disease, with its role in inflammatory bowel disease (IBD)—including Crohn’s disease and ulcerative colitis—being particularly significant. Among the many factors influencing the gut microbiota, dietary components such as fibers, fats, and polyphenols have received substantial attention. However, nitrogen-containing compounds, such as amino acids, nitrates, urea, and even nucleic acids, such as purines, remain underexplored despite their integral role in shaping microbial ecology, host metabolism, and immune responses. Some of these compounds are metabolized by gut bacteria into bioactive molecules such as short-chain fatty acids, ammonia, …

Antimicrobial Susceptibility Profiles (Mic And Mmc) Against Mycoplasma Gallisepticum And M. Synoviae Isolated From Chicken Farms In Thailand, Kriengwich Limpavithayakul, Alongkorn Amonsin, Nataya Charoenvisal, Arithat Limsatanun, Katanyu Yangsuk, Sumrit Toopiya, Füsun Güngör, Esther Schonewille, Javier Uriarte, Somsak Pakpinyo

The Thai Journal of Veterinary Medicine

Mycoplasma gallisepticum (MG) and M. synoviae (MS) are important pathogens causing significant economic losses in poultry production. Disease prevention and control strategies include vaccination, antimicrobial therapy, and strict biosecurity measures. The present study provides, for the first time, both minimum inhibitory concentration (MIC) and minimum mycoplasmacidal concentration (MMC) values as antimicrobial susceptibility profiles of Thai MG and MS field isolates. This study aimed to evaluate the susceptibility of five MG and ten MS isolates to various antimycoplasma drugs: doxycycline, lincomycin-spectinomycin, tiamulin, tilmicosin, tylosin, and tylvalosin, using a microdilution broth assay. For MG isolates, tilmicosin had the highest mean MIC (12.5 …

Empirical Analysis Of Incentivized Energy Assessment Recommendations And Iiot Cost-Effectiveness In U.S. Smes, Fatemeh Ghafari

LSU Master's Theses

The industrial sector in the United States accounted for 33% of total energy consumption in 2022. Small and medium-sized enterprises (SMEs), which comprise 99.9% of U.S. businesses present a critical opportunity for energy efficiency improvements. Although energy audits provide actionable Assessment Recommendations (ARs) to reduce consumption, high implementation costs remain a key barrier to adoption.

While prior studies have explored rebate programs, most are limited to residential and commercial sectors or focus narrowly on specific technologies or geographic areas for the industrial sector. The objective of this study is to empirically investigate the “Incentivized Assessment Recommendation” (IAR) trends and to …

Direct Histone Proteoform Profiling Of The Unannotated, Endangered Coral Acropora Cervicornis, Cassandra N Fuller, Sabrina Mansoor, Kevin Jeanne Dit Fouque, Lilian Valadares Tose, Javier Rodriguez-Casariego, Mariangela Kosmopoulou, Detlev Suckau, Francisca N De Luna Vitorino, Benjamin A Garcia, Jose M Eirin-Lopez, Francisco Fernandez-Lima

2020-Current year OA Pubs

Epigenetic modifications directly regulate the patterns of gene expression by altering DNA accessibility and chromatin structure. A knowledge gap is presented by the need to directly measure these modifications, especially for unannotated organisms with unknown primary histone sequences. In the present work, we developed and applied a novel workflow for identifying and annotating histone proteoforms directly from mass spectrometry-based measurements for the endangered Caribbean coral Acropora cervicornis. Combining high-accuracy de novo top-down and bottom-up analysis based on tandem liquid chromatography, trapped ion mobility spectrometry, non-ergodic electron-based fragmentation, and high-resolution mass spectrometry, near complete primary sequence (up to 99%) and over …

Chondrocyte-Specific Knockout Of Piezo1 And Piezo2 Protects Against Post-Traumatic Osteoarthritis Structural Damage And Pain In Mice, Erica V Ely, Kristin L Lenz, Sophie G Paradi, Seth Ack, Abraham Behrmann, Sarah Dunivan, Lauryn Braxton, Wolfgang Liedtke, Yong Chen, Kelsey H Collins, Farshid Guilak

2020-Current year OA Pubs

BACKGROUND: Osteoarthritis (OA) is a debilitating joint disease characterized by cartilage degeneration, synovial inflammation, and bone remodeling, with limited therapeutic options targeting the underlying pathophysiology. Mechanosensitive ion channels Piezo1 and Piezo2 play crucial roles in chondrocyte responses to mechanical stress, mediating mechanotransduction pathways that influence chondrocyte survival, matrix production, and inflammatory signaling, but their distinct contributions to OA pathogenesis remain unclear.

METHODS: Using inducible, chondrocyte-specific Aggrecan-Cre (Acan) mice, we investigated Piezo1, Piezo2, and combined Piezo1/2 conditional knockouts (cKOs) using the destabilization of the medial meniscus (DMM) model of post-traumatic OA in male and female mice. Pain and behavioral assessments were …

Mouse Metastable Epialleles Are Extremely Rare, Chathura J Gunasekara, Uditha Maduranga, Taylor Zhang, Jonathan N Wells, Maria S Baker, Eleonora Laritsky, Yumei Li, Cristian Coarfa, Yi Zhu, Robert A Waterland

Faculty, Staff and Students Publications

Metastable epialleles (MEs) are genomic loci at which epigenetic marks are established stochastically during early embryonic development and maintained during subsequent differentiation and throughout life, leading to stable epigenetic and phenotypic variation among genetically identical individuals. Although MEs were first described in mice over 20 years ago, the extent of epigenetic metastability in the mouse genome remains unknown. We present the first unbiased genome-wide screen for MEs in mice. Using deep whole-genome bisulfite sequencing across tissues derived from the three embryonic germ layers in isogenic C57BL/6J mice, we identified only 29 MEs, precisely localizing them and documenting their rarity. Consistent …