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The Bg News September 10, 2025, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. September 10, 2025. Volume 105-Issue 03.

The "Secret Of Seven Stones": Short-Term Efficacy Of An Online Intergenerational Sexual Health Education Game For Early Adolescents And Their Parents, Ross Shegog, Christine Markham, Melissa Peskin, Robert C Addy, Sara Dube, Diane Santa Maria, Susan Tortolero Emery, Johnny M Wilkerson, Elizabeth Baumler, Laura Armistead, Pooja Chaudhary, Hsing-Yi Song, Angela Spencer, Jeffery Mclaughlin

Faculty, Staff and Student Publications

Objectives: Intergenerational games offer a potential channel to impact parent-youth sexual health communication. The "Secret of Seven Stones" (SSS) is an 18-level online adventure game and parent website designed to engage parents and youth (11-14 years) in conversations about healthy dating relationships and sexual behavior and to provide sexual health skills training to youth. Study hypotheses were that SSS exposure would increase sexual health parent-child communication, increase youth intentions to delay sexual debut, and reduce youth exposure to situations that promote sexual activity.

Materials and Methods: SSS was evaluated in the homes of parent-youth dyads randomly assigned to intervention ( …

Vital Brookdale Llc V. Moore

All Decisions

In this holdover proceeding, the court denied the landlord's application for a default judgment and dismissed the petition. The landlord alleged the tenant failed to comply with income recertification procedures. The court found the petition improperly verified by an attorney lacking personal knowledge. Crucially, the court held that the lease provision, which allowed termination upon ten days' notice for non-compliance, constituted a condition, not a conditional limitation. Consequently, a summary holdover proceeding could not be maintained as a conditional limitation, providing for automatic lease expiration upon notice, was absent.

Retinoid-X-Receptor As A Mediator Of Poststroke Recovery By Reversing Age-Associated Phenotypes Of Microglia/Hematogenous Macrophages, Shun-Ming Ting, Xiurong Zhao, Guanghua Sun, Mercedes Ricote, Jaroslaw Aronowski

Faculty, Staff and Student Publications

After stroke, microglia and hematogenous macrophages, together referred to as MΦ, clear dead cells and cellular debris in the infarcted brain through phagocytosis as an essential part of the recovery process. However, the phagocytic capability of MΦ declines with age. Furthermore, aged MΦ become overactivated in response to stroke, enhancing secondary brain injury. In this study, we demonstrated that by reversing the age-related dysfunctions in MΦ through activating the retinoid X receptor (RXR), the recovery after stroke in the aged brain could be improved. Using RNA-sequencing, we compared the transcriptomes between MΦ isolated from the brains of young and aged …

Infectious Prions In Brains And Muscles Of Domestic Pigs Experimentally Challenged With The Bse, Scrapie, And Cwd Agents, Francisca Bravo-Risi, Fraser Brydon, Angela Chong, Kane Spicker, Justin J Greenlee, Glenn Telling, Claudio Soto, Sandra Pritzkow, Marcelo A Barria, Rodrigo Morales

Faculty, Staff and Student Publications

Experimental studies suggest that animal species not previously described as naturally infected by prions are susceptible to prion diseases affecting sheep, cattle, and deer. These interspecies transmissions may generate prions with unknown host ranges. Pigs are susceptible to prions from different origins, including deer chronic wasting disease (CWD), sheep scrapie, and bovine spongiform encephalopathy (BSE). Here, we studied prions in brains and muscles from pigs previously infected with these different prion sources. Specifically, we measured the total prion protein (PrP) and PK-resistant PrP by western blot. Seeding activity in these tissues was evaluated using the protein misfolding cyclic amplification (PMCA) …

Inhibition Of The Ufd-1-Npl-4 Complex Triggers An Aberrant Immune Response In Caenorhabditis Elegans, Rajneesh Rao, Alejandro Aballay, Jogender Singh

Faculty, Staff and Student Publications

The UFD-1 (ubiquitin fusion degradation 1)-NPL-4 (nuclear protein localization homolog 4) heterodimer is involved in extracting ubiquitinated proteins from several plasma membrane locations, including the endoplasmic reticulum. This heterodimer complex helps in the degradation of ubiquitinated proteins via the proteasome with the help of the AAA+ATPase CDC-48. While the ubiquitin-proteasome system is known to have important roles in maintaining innate immune responses, the role of the UFD-1-NPL-4 complex in regulating immunity remains elusive. In this study, we investigate the role of the UFD-1-NPL-4 complex in maintaining

Moving Forward With Maboo Liyan Boorroo: River Monitoring And Communicating Heritage And River Keeper Stories: Research Workshop Iii Summary Report, Anne Poelina, Tod Jones, Martin Brueckner, Pierre Horwitz, Sven Ouzman, Kylie Wrigley, Community Research Practioners - Martuwarra River Keepers

Reports accepted as research outputs

This Report provides a summary of activities and outcomes from the Maboo Liyan Boorroo Workshop III, held in June 2025. Three community Workshops have been held, involving an external multi-disciplinary and multi-institutional research team (the research team) visiting and working with the Yurmulun Pandanus Park Community and the Martuwarra Fitzroy River Council River Keepers. This visit followed two workshops with the community held in November 2021 (see Voices for the Martuwarra: Mapping Values with Fitzroy River Communities, 2021) and August 2022 (see Working together for Maboo Liyan Boorroo, 2022). This summary report provides detail on Workshop III discussions, activities and …

Longitudinal Associations Of Epigenetic Aging With Cognitive Aging In Hispanic/Latino Adults From The Hispanic Community Health Study/Study Of Latinos, Myriam Fornage, Wassim Tarraf, Rui Xia, Adriana Ordonez, Tamar Sofer, Freddie Márquez, Bharat Thyagarajan, Gregory A Talavera, Linda C Gallo, Charles Decarli, Hector M González

The Brown Foundation: Institute of Molecular Medicine

Due to the paucity of longitudinal DNA methylation data (DNAm), especially among Hispanic/Latino adults, the association between changes in epigenetic clocks over time and cognitive aging phenotypes has not been investigated. This longitudinal study included 2671 Hispanic/Latino adults (57 years; 66% women) with blood DNAm data and neurocognitive function assessed at two visits ~7 years apart. We evaluated the associations of 5 epigenetic clocks and their between-visit change with multiple measures of cognitive aging that included a global and domain-specific cognitive function score at each visit, between-visit change in global and domain-specific cognitive function score, and MCI diagnosis at visit …

Flowing Knowledge: Connecting Education, Watersheds, And Our World, Taylor Lemieux

The Cicadian

The main theme of Taylor Lemieux’s story is the transformative power of experiential environmental education. Through personal memories and professional experiences, she illustrates how hands-on learning in nature fosters curiosity, resilience, and a deep sense of stewardship. Her journey emphasizes that meaningful education goes beyond textbooks—it connects learners to the world around them.

Gardens As Pathways To Environmental Education For All Ages, Lacey Anderson

The Cicadian

Gardens provide hands-on opportunities for environmental education that extend beyond food production, encompassing ecological literacy, sustainability practices, experiential learning, and community engagement. This article uses a creative nonfiction approach to examine the author’s personal journey from reluctant gardener to advocate for learning gardens. Through narrative reflection of her own family’s gardening experiences during the COVID-19 pandemic, the author illustrates how gardening fosters intergenerational learning, socio-emotional development, and curiosity-driven exploration of ecological systems. The article highlights how gardens function as accessible entry points for lifelong learners of all ages, demonstrating that environmental literacy can emerge outside of traditional scientific expertise. Ultimately, …

“Grow Your Plants, But Most Importantly, Grow Yourself”: Women, Resilience, And Cultural Continuity In Jamaican And Diaspora Gardens, Giovanni Whyte

The Cicadian

This essay explores the cultural, personal, and transformative power of gardening through the stories of four women—Brenda, Linda, Keisha, and Janice—whose lives span Jamaica and its diaspora. Their narratives reveal gardening as more than food cultivation but the practice of resilience, healing, and cultural continuity. Brenda honors her ancestral legacy in St. Elizabeth; Linda finds solace after loss; Keisha fosters socioemotional growth among urban students; and Janice embraces sustainability in suburban America. Together, their experiences illustrate how gardening nurtures identity, strengthens communities, and connects people to land, memory, and future generations.

Anishinaabe Nibiing: Anishinaabe Waterscapes And Canoe Building As Traditional Ecological Knowledge, Jeremy Kingsbury

The Cicadian

This paper explores the cultural, ecological, and technological significance of birch bark canoe (wiigwaasi-jiimaan) building among the Anishinaabe people, emphasizing their identity as an inland maritime society. Drawing on historical accounts, oral traditions, and personal experience as a park ranger, the author examines the intricate process of harvesting materials and constructing canoes, highlighting the deep environmental knowledge and gendered labor involved. The canoe served not only as a vital means of transportation and subsistence—facilitating fishing, wild rice harvesting, and seasonal migration—but also as a symbol of familial and spiritual connection. Through detailed descriptions of material selection and craftsmanship, …

Introduction To Our Inaugural Issue, Lacey Anderson, Mary Moroney-Fernandez, Giovanni E. Whyte

The Cicadian

No abstract provided.

Leisure, Events. Tourism, And Recreation In The Spectrum Of Fashion Representation: Toward An Integrative Typological Framework, Su Yun Bae

Visions in Leisure and Business Monographs

This study develops a new typology of fashion representation situated at the intersection of leisure, events, tourism, and recreation. Existing fashion typologies, while valuable in mapping class, culture, or consumer psychographics, often overlook the lived sartorial practices that emerge in free time and experiential settings. To address this gap, a descriptive analysis was undertaken using four types of material: academic and industry literature, online media sources, visual and experiential data, and professional insights from the tourism field. This triangulated approach identified five key categories: Rebel, Independent, Traditional, Symbolic, and Sophisticated that collectively form a contextual fashion spectrum. The typology captures …

The Genus Androctonus Ehrenberg, 1828 (Scorpiones: Buthidae) In Oman, Graeme Lowe

Euscorpius

The taxonomic position of Androctonus populations in Oman was investigated by analyzing morphological variation in a comprehensive sample representing 150 records gathered from 95 localities spread throughout the country. Two new allopatric species are described, separated by multivariate morphometric analysis and meristic characters: (1) A. omanensis sp. n., distributed across most of Oman, is characterized by wider, deeper metasomal segments IV–V, shorter legs, more robust pedipalps, more granules on lateral inframedian carinae of metasoma II–III, and sparser setation on basitarsal spurs; and (2) A. ammophilus sp. n., distributed in the dunes of the Rub’ al-Khali (Empty Quarter) of …

Exploring The Relative Effects Of Natural Gas And Biogas Cooking On Indoor Air Quality In Residential Kitchens, Wande Benka-Coker, Kailey Sipe, Dinela Dedic, Alexander Jones, Bramley Hawkins, Emily Lyons, Matt Steiman, Megan L. Benka-Coker

Health Sciences Faculty Publications

Indoor air pollution from gas stove combustion remains a public health concern, given links to adverse cardiorespiratory health effects, yet few studies have characterized or compared the air quality impacts of different gas-based cooking fuels. We investigated kitchen-level concentrations of nitrogen dioxide (NO2) and fine particulate matter (PM2.5) concentrations in four homes in Central Pennsylvania that used natural gas and/or biogas fueled stoves. We conducted time-resolved kitchen monitoring and assessed pollutant concentrations during cooking and non-cooking periods. We applied linear mixed-effect regression models with kitchen-level random effects and time-varying covariates to estimate the influence of fuel type on indoor air …

The Prospector, September 9, 2025, Utep Student Publications

The Prospector

No abstract provided.

Compositions And Uses Thereof For Treatment Of Idiopathic Preterm Birth, Charles Lockwood, Ozlem Guzeloglu-Kayisli, Umit Ali Kayisli, Frederick Schatz

USF Patents

Disclosed are compositions and methods for delaying or preventing idiopathic preterm birth.

Nanoparticles And Nanogel Drug Compositions For Treatment Of Age-Related Macular Degeneration, Vijaykumar Bhadabhai Sutariya, Priyanka Sureshbhai Bhatt, Vipul B. Amin, Srinivas M. Tipparaju

USF Patents

Disclosed are nanoparticles and nanogel drug compositions and the use thereof for treating age-related macular degeneration.

[Pdf] From Usf.Edu Nanoparticles And Nanogel Drug Compositions For Treatment Of Age-Related Macular Degeneration, Vijaykumar Bhadabhai Sutariya, Priyanka Bhatt, Vipul B. Amin, Srinivas M. Tipparaju

Pharmacy Faculty/Staff Publications

Disclosed are nanoparticles and nanogel drug compositions and the use thereof for treating age-related macular degeneration.

Stayin' Alive (Even Without Oxygen): Retinal Development In Austrofundulus Limnaeus, Carmen Zecilia Rodriguez

Dissertations and Theses

The vertebrate eye is one of the most metabolically active organs in the body and is particularly sensitive to environmental stressors such as oxygen deprivation. Understanding how eye development proceeds under such conditions can provide critical insights into mechanisms of cellular resilience, tissue organization, and developmental plasticity. The annual killifish Austrofundulus limnaeus represents a unique model for investigating these processes due to its remarkable tolerance to anoxia during embryogenesis. However, the wild-type form is heavily pigmented, limiting the effectiveness of traditional imaging techniques for studying eye development. This thesis characterizes eye development and anoxia resilience in both wild-type and melanin-deficient …

Endothelin B Receptor Inhibition Rescues Aging-Dependent Neuronal Regenerative Decline, Rui Feng, Sarah F Rosen, Irshad Ansari, Sebastian John, Michael B Thomsen, Oshri Avraham, Cedric G Geoffroy, Valeria Cavalli

2020-Current year OA Pubs

Peripheral sensory neurons regenerate their axons after injury to regain function, but this ability declines with age. The mechanisms behind this decline are not fully understood. While excessive production of endothelin 1 (ET-1), a potent vasoconstrictor, is linked to many diseases that increase with age, the role of ET-1 and its receptors in axon regeneration is unknown. Using single-cell RNA sequencing, we show that satellite glial cells (SGCs), which completely envelop the sensory neuron soma residing in the dorsal root ganglia (DRG), express the endothelin B receptor (ETBR), while ET-1 is expressed by endothelial cells. Inhibition of ETBR ex vivo …

Fatty Acid 2-Hydroxylase Facilitates Rotavirus Uncoating And Endosomal Escape, Enkai Li, Ruochen Zang, Takahiro Kawagishi, Wei Zhang, Kruthika Iyer, Gaopeng Hou, Qiru Zeng, Rita M Meganck, Susan R Ross, Xin Wang, Xiong Su, Siyuan Ding

2020-Current year OA Pubs

Despite the clinical significance of many nonenveloped viruses, the molecular mechanisms of their internalization and membrane penetration are not well understood. Rotaviruses (RVs) are nonenveloped double-stranded RNA viruses and the leading cause of severe dehydrating diarrhea in infants and young children. We identified fatty acid 2-hydroxylase (encoded by

Sleep Architecture And Dementia Risk In Adults: An Analysis Of 5 Cohorts From The Sleep And Dementia Consortium, Stephanie Yiallourou, Andree-Ann Baril, Crystal Wiedner, Jeffrey R Misialek, Christopher E Kline, Stephanie Harrison, Ethan Cannon, Qiong Yang, Rebecca Bernal, Alycia Bisson, Dibya Himali, Marina Cavuoto, Antoine Weihs, Alexa Beiser, Rebecca F Gottesman, Yue Leng, Oscar Lopez, Pamela L Lutsey, Shaun M Purcell, Susan Redline, Sudha Seshadri, Katie L Stone, Kristine Yaffe, Sonia Ancoli-Israel, Qian Xiao, Eleni Okeanis Vaou, Jayandra J Himali, Matthew P Pase

Faculty, Staff and Student Publications

Study objectives: Poor sleep may play a role in the risk of dementia. However, few studies have investigated the association between polysomnography (PSG)-derived sleep architecture and dementia incidence. We examined the relationship between sleep architecture and dementia incidence across five US-based cohort studies from the Sleep and Dementia Consortium.

Methods: Percent of time spent in stages of sleep (N1, N2, N3, rapid eye movement sleep), wake after sleep onset, sleep maintenance efficiency, apnea-hypopnea index, and relative delta power were derived from a single night home-based PSG. Dementia was ascertained in each cohort using its cohort-specific criteria. Each cohort performed Cox …

Therapeutic Restoration Of Mitochondria-Endoplasmic Reticulum Cross Talk For Osteoarthritis, Mingzhuang Hou, Yifan Ma, Yaoge Deng, Yubin Wu, Yanrun Zhu, Yang Liu, Xiaoping Li, Lili Yu, Zirui He, Yifan Wang, Shiyan Dong, Xiaowei Xia, Jianfeng Yu, Chenqi Yu, Kang Kang, Yingjie Lu, Lili Sun, Betty Y S Kim, Yuan Yuan, Yijian Zhang, Wen Jiang, Xuesong Zhu

Faculty, Staff and Student Publications

Osteoarthritis is a prevalent joint disease in the aging population. The hallmark of osteoarthritis is the degeneration of the joint cartilage, characterized by changes in chondrocytes including mitochondrial dysfunction. However, the precise mechanisms of how this affects chondrocyte homeostasis and whether such processes can be explored as therapeutic targets for osteoarthritis remain unclear. Here, we show that impaired mitochondrial function and disrupted cartilage matrix metabolism due to loss of mitofusin-2 (MFN2) expression in chondrocytes leads to the development of osteoarthritis. Sirtuin-3 (SIRT3), a key regulator of mitochondrial function, plays a critical role in modulating MFN2 to restore mitochondrial dynamics, reduce …

Trade Agreements Have Helped Prohibit Forced Labor, Desiree Leclercq

Scholarly Works

While policymakers today debate the future of trade policy, the real story lies in the proven wins quietly shaping economies and improving lives worldwide. This series showcases ten compelling wins in international trade that demonstrate the success of crossborder commerce and open trade policies.

Smart Aquaculture Technology: Building Climate Resilience And Food Security In The Agrifood Supply Chain, Ikape Simon I., Goma Ruth P., Lise Hunter, Ed-Idoko John O., Christiana O. N.

Plymouth Business School

This paper examines the impacts of climate change on fish production within the agrifood supply chain and its implications for food security. It reviews smart aquaculture technologies as key adaptation and mitigation strategies for sustainable fish production and resilient food security. Adaptation measures include data-driven tools for site and species selection, as well as automated monitoring systems and predictive models that enable proactive risk management under climate variability. Mitigation strategies focus on reducing the sector’s carbon footprint through optimized feed utilization, waste reduction, and the integration of renewable energy sources. Findings suggest that smart aquaculture not only strengthens production efficiency …

Testis Expressed 50 Is Essential For Maintaining Sperm Acrosome Integrity During Epididymal Transit, Saori Haga, Kaori Nozawa, Ferheen Abbasi, Katarzyna Kent, Naoko Nagasawa, Tsutomu Endo, Haruhiko Miyata, Masahito Ikawa, Martin M Matzuk, Yoshitaka Fujihara

Faculty, Staff and Students Publications

In mammals, sperm formation is completed in the seminiferous tubules within the testis, and sperm maturation occurs during the epididymal transit of the spermatozoa. Sperm morphology drastically changes when abnormal spermatozoa migrate from the testis to the epididymis. Detailed molecular mechanisms for sperm survival in the epididymis have not been determined yet. Globozoospermia is a cause of male infertility and is characterized by round-headed spermatozoa without acrosomes, an abnormal sperm nuclear membrane, and sperm midpiece defects. Testis expressed 50 (Tex50) is a testis-enriched gene that is expressed in mice and humans. Using CRISPR-Cas9, we generated Tex50 knockout (KO) …

Computationally Resolved Neuroprogenitor Cell Biomarkers Associate With Human Disorders, Gerarda Cappuccio, William T Choi, Fatih Semerci, Jill A Rosenfeld, Toni Claire Tacorda, Guantong Qi, Anthony W Zoghbi, Yi Zhong, Hu Chen, Pengfei Liu, Zhandong Liu, Mirjana Maletić-Savatić

Duncan NRI Faculty and Staff Publications

Adult hippocampal neurogenesis, the process of generating new neurons, relies on a rare population of neural stem and progenitor cells (NPCs) within the dentate gyrus complex microenvironment. Discovering the specific genes that define these cells is vital yet challenging due to overlapping expression patterns, limiting detection of rare cell populations using traditional approaches. By employing the computational digital sorting algorithm (DSA) that deconvolves complex gene expression data based on pattern recognition, we identified 129 genes enriched in murine NPCs. We validated these genes against published single-cell RNA sequencing (scRNA-seq) data and discovered that 25 human orthologs were known to cause …

Dissecting The Effect Of Mitochondrial Bcat Inhibition In Methylmalonic Acidemia, Madeline G Hemmingsen, Guo-Fang Zhang, Yunhan Ma, Hannah Marchuk, Kalyani R Patel, Tong Chen, Xinning Li, Mark Chapman, Sabrina Collias, Dolores H Lopez-Terrada, James Beasley, Ashlee R Stiles, Randy J Chandler, Charles P Venditti, Sarah P Young, Mercedes Barzi, Beatrice Bissig-Choisat, Doug Krafte, Christopher B Newgard, Karl-Dimiter Bissig

Faculty, Staff and Students Publications

Methylmalonic acidemia (MMA) is a severe metabolic disorder affecting multiple organs because of a distal block in branched-chain amino acid (BCAA) catabolism. Standard of care is limited to protein restriction and supportive care during metabolic decompensation. Severe cases require liver/kidney transplantation, and there is a clear need for better therapy. Here, we investigated the effects of a small molecule branched-chain amino acid transaminase (BCAT) inhibitor in human MMA hepatocytes and an MMA mouse model. Mitochondrial BCAT is the first step in BCAA catabolism, and reduction of flux through an early enzymatic step is successfully used in other amino acid metabolic …