Digital Commons Network^™

Relationship Between Quantitative Mri Ute T2* Of Acl Autografts And Bmi-Normalized Knee Laxity Within The First Year After Acl Reconstruction, Alonso Figueroa, Tomasz Bugajski, Dillon Humpal, Manickam Kumaravel, Walter Lowe, Payam Zandiyeh

Faculty, Staff and Student Publications

Background: The anterior cruciate ligament reconstruction (ACLR) graft undergoes a remodeling process that affects its structural properties. Ultrashort echo time T2* (UTE-T2*) imaging has been instrumental in examining this process. However, more research is needed on the postoperative relationship between UTE-T2* of the graft and its mechanical properties.

Purpose: To longitudinally examine ACL graft changes after ACLR using UTE-T2* decay coefficients and knee laxity and explore their relationship.

Study design: Case series; Level of evidence, 4.

Methods: A total of 31 patients who underwent ACLR had magnetic resonance imaging of their knees at 1, 6, and 12 months after surgery …

Pka-Driven Spp1 Activation As A Novel Mechanism Connecting The Bone Microenvironment To Prostate Cancer Progression, Pablo Sanchis, Agustina Sabater, Julia Lechuga, Jimena Rada, Rocio Seniuk, Gaston Pascual, Mora Gatti, Juan Bizzotto, Peter D A Shepherd, Jun Yang, Javier Cotignola, Elba Vazquez, Joaquin Mateo, Pia Valacco, Estefania Labanca, Christopher Logothetis, Geraldine Gueron, Nicolas Anselmino

Faculty, Staff and Student Publications

Prostate cancer (PCa) bone metastasis (BM) poses a significant clinical challenge due to the heterogeneity of treatment responses and patient outcomes. In this study, we examined the role of Protein Kinase A (PKA) signaling in modulating the expression of osteopontin (SPP1/OPN), a protein associated with poor prognosis, within a subset of PCa BM patients. By integrating multi-omics results we identified a novel mechanism in which bone-derived type-I collagen (Col1a1) and fibronectin (Fn1) stimulate SPP1 expression in PCa cells through the activation of PKA signaling. This bone-induced regulation of SPP1 was confirmed both in vitro, using PCa-bone co-culture systems (PC3 or …

From Nociception In Aneural Animals To Human Suffering: Toward A Comparative Biology Of Pain, Edgar T Walters

Faculty, Staff and Student Publications

Pain is a core feature of human life, but systematic comparisons of this biological trait across taxa have been rare. A broadly accepted definition based on human experience emphasizes dual features of pain: a sensory (discriminative) component for sensing and monitoring tissue injury, and an affective (emotional) component to motivate avoidance of tissue distress. Conscious pain is coupled to unconscious nociception (detection of incipient or existing injury). This Review considers nociception and pain across phyla within a comparative framework, addressing basic questions about evolutionary origins, mechanisms and functions of pain. The occurrence of adaptive cellular responses to injury in virtually …

Better Digital Contracts With Prosocial Friction-In-Design, Brett Frischmann, Moshe Y. Vardi

Faculty Publications

Contract law is supposed to enable people to reach genuine agreements and cooperate. If this ideal was ever a reality, the rise of mass market contracts and boil­erplate rendered it pure fiction. Modern consumer contracts are incomprehensible to most people. No one reads them anyway.

Digital contracting involves design features that amplify traditional boilerplate harms and create others. For example, digital contracting is too cheap; low marginal costs lead to overexpansion in scale and scope. To make matters worse, the loss of autonomy from repeat engagement with digital contracting systems is pernicious. People become increasingly predictable and programmable as digital …

Divergent Sensory Transcriptomic Profiles In Positive And Negative Learning In Bicyclus Anynana Butterflies, Yi Ting Ter, Erica L. Westerman

Biological Sciences Faculty Publications and Presentations

Mate preference learning, where individuals learn to prefer or avoid specific phenotypes during mate selection, is pervasive across animal taxa and influences reproductive isolation and trait evolution. Despite its significance, the genetic basis underlying the associated valence attribution (whether to prefer or avoid) remains largely unclear. Both in terms of what genes are associated with attributing valence, and whether valence attribution is associated with transcriptional changes in both sensory tissues and neural circuits in the brain, or is restricted to the brain. Here, we investigate the neurogenomic basis of positive and negative mate preference learning using Bicyclus anynana butterflies. We …

Suturing Education For Athletic Trainers: An Evidence-To-Practice Review, Morgan K. Webb, Brett T. Heim, Allyson E. Ritchey, Kenya Moore, Zachary K. Winkelmann

Clinical Practice in Athletic Training

Teaching suturing skills to medical students is a critical component of their education. Implementing suturing into a comprehensive framework is developed from how professors teach the skill. Suturing is a required skill by the General Medical Council that all medical students must have, and how it is being introduced to new students is changing. This review aimed to summarize different educational interventions and determine the most efficient and cost-effective way to teach future suturing skills. The original systematic review included 25 articles in the final data synthesis. Fourteen studies were randomized control trials, six were quasi-experimental, and five were observational. …

Learning Opportunities 2025/2026, Illinois Math And Science Academy

Course Catalogs

The graduation requirements of the Illinois Mathematics and Science Academy are established by the IMSA Board of Trustees. Each semester students must take a minimum of five academic courses (2.5 credits) for a letter grade (not Pass/Fail) not including SIR, Internship, Credentials and Independent Study. Students may enroll in a maximum of seven courses each semester including academic courses, SIR, Internship, Credentials, and Independent Study. The College and Academic Counselor approves enrollment for students in all courses and experiences. Academic courses must be taken for a grade in order to count towards graduation credit.

The Advocate (Fall 2025), Lewis & Clark Law School

The Advocate

No abstract provided.

Check Out The Library, 2025 Fall Issue, Cal Poly Humboldt Library

Library Publications

Issue 20

Preliminary Investigation Of Nitrogen Rate Influence On Irrigated Bermudagrass Forage Production, Bronc Finch, Lance Blythe

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Bermudagrass (Cynodon dactylon) forage production recommendations are often developed in natural environments with available water limitations, often resulting in highly variable responses and lower average responses. As farmland ownership changes and agriculture and irrigation technologies become more affordable the amount of irrigated hay production has increased. While much of the agronomic management does not differ between rain-fed and irrigated environments, nutrient use and uptake dynamics may. This requires a reevaluation and potential adjustment of current recommendations to allow for increased yield potential of irrigated production systems without detrimental impacts on the system. The objective of this study was to identify …

Does The Pto Have The Power To Ask Where You Sleep At Night? Pamela Chestek, The Patent Act, And The Apa Say No, Jessica Manzon

Cardozo Law Review

Imagine this scenario: You apply for a trademark, following the longstanding practice of listing your business’s PO Box on the application. Days later, you receive a notice from the U.S. Patent and Trademark Office (PTO): Your application was rejected for failure to disclose your domicile address—a requirement imposed under the 2019 U.S. Counsel Rule. Having previously suffered harm from making your home address public, you are understandably reluctant to expose it again for something as routine as a trademark application. You stand firm in withholding your domicile address, citing privacy concerns. As a result, your application remains denied, and when …

From Matrimony To Autonomy: Divorce As A Fundamental Right, Karin Carmit Yefet

Cardozo Law Review

Liberal divorce is under assault. Yet this development—one that arguably may shape the everyday life of Americans more profoundly than nearly any other domain of state law—has elicited surprisingly little scholarly inquiry. Because divorce has long fallen within the province of states and hewed to the whim of state legislatures, restrictions on divorce have rarely inspired constitutional analysis. As a result, the constitutional architecture necessary to conceptualize—let alone resolve—the question of how divorce law intersects with fundamental rights remains strikingly wanting. Indeed, one of the enduring puzzles of constitutional scholarship is the diametrically opposed treatment of marriage and divorce. While …

Multiscale Geometric Analysis In Endovascular Therapies: Ex Vivo, In Silico Approaches, Dima Hussein Ali Bani Hani

Theses and Dissertations

In this work, we address a persistent global challenge of vascular disease, specifically peripheral artery disease (PAD), and arteriovenous fistula (AVF) complications in patients with end-stage kidney disease (ESKD). The important role of vascular geometry in disease intervention plans and the development of endovascular therapeutic strategies (e.g., Drug-coated balloon (DCBs)) is critical in addressing these challenges.

This study evaluates the feasibility of co-delivery of paclitaxel (PTX) and valsartan (VAL) using urea-based coatings in DCB, analyzes the coating morphology and microstructural changes to improve therapeutic results. A computational finite element model was developed to complement experimental work, simulate tissue-coating interactions, compute …

Gut Microbiome Dynamics In Heart Failure And The Therapeutic Potential Of Nmeg-Cgrp, Kamryn Michael Gleason

Theses and Dissertations

Heart failure (HF) is increasingly recognized as a multisystem disease often linked to gut dysbiosis; however, its specific effects on gut microbial composition remain poorly understood. This study examined long-term changes in the gut microbiome in a murine HF model induced by transverse aortic constriction (TAC) and evaluated the effects of NMEG-CGRP. TAC mimics pressure overload-induced cardiac dysfunction, replicating key features of HF. CGRP, a neuropeptide with vasodilatory and cardioprotective effects, shows potential as a therapy for HF but is limited by rapid degradation. A stabilized analog, NMEG-CGRP, was used to assess its impact on cardiac and gastrointestinal health. Mice …

The Role Of Fibroblast Activation Protein On Left Ventricular Growth And Extracellular Matrix Remodeling As A Function Of Age And Pressure Overload, Amelia Marie Churillo

Theses and Dissertations

Fibroblast activation protein (FAP) is abundantly expressed in cancer associated fibroblasts and contributes to extracellular matrix (ECM) remodeling. Recent studies using imaging techniques have identified increased levels of FAP in the left ventricle (LV) of patients identified as at risk for developing heart failure. However, the role of FAP in regulated LV myocardial structure and function remains unclear. This project tested two hypotheses: First, genetic ablation of FAP would modify LV structure and function and be more pronounced with aging. Second, genetic ablation of FAP would modify LV structure and function with LV pressure overload (LVPO) accompanied by ECM remodeling.

Fue Evocations: A Culturally-Informed Performance Guide To Approaching Works For The Western Concert Flute Inspired By Traditional Japanese Flutes, Chase Michael Ketron

Theses and Dissertations

The purpose of this document is to create a culturally-informed and aesthetically accurate performance preparation guide for Western concert flute players seeking to perform works inspired by traditional Japanese flutes, or fue, such as the shakuhachi and nohkan.¹ While many pieces like these exist, there are limited resources detailing how to emulate the traditional Japanese flutes and their performance practices. The composers of these works often do well to provide notation for producing the specific sounds or effects they are trying to replicate, but these are non-standardized and thus vary from composer to composer. In addition, the traditional …

The Effect Of Fascicular Elastin On The Mechanical And Functional Properties Of Healthy, Damaged, And Healing Tendon, Shawn Pavey

McKelvey School of Engineering Graduate Student Theses & Dissertations

Mechanical properties of tendon are highly influenced by structural protein composition and microscopic sub-structures. Within the largest subunit of tendon, the fascicle, the role of the elastin protein remains understudied despite impressive extensibility and fatigue resistance of its resulting elastic fibers. While previous work catalogued contributions of fascicular elastin across tendon type and species, the anticipated effects of elastin in fatigue and healing have not yet been explored. While previous knockout mouse models showed that disruption of elastic fibers led to altered mechanical properties (e.g., increased linear modulus), these models depended on heterozygous elastin deficiency or indirect knockout of proteins …

A Modified Fama-Macbeth Model Based On The Single-Index Model, Mariam Jumaah Mousa, Munaf Yousif Hmood

Journal of Economics and Administrative Sciences

The aim of this essay is to use a single-index model in developing and adjusting Fama-MacBeth.  Penalized smoothing spline regression technique (SIMPLS) foresaw this adjustment.  Two generalized cross-validation techniques, Generalized Cross Validation Grid (GGCV) and Generalized Cross Validation Fast (FGCV), anticipated the regular value of smoothing covered under this technique. Due to the two-steps nature of the Fama-MacBeth model, this estimation generated four estimates: SIMPLS(FGCV) - SIMPLS(FGCV), SIMPLS(FGCV) - SIM PLS(GGCV), SIMPLS(GGCV) - SIMPLS(FGCV), SIM PLS(GGCV) - SIM PLS(GGCV). Three-factor Fama-French model—market risk premium, size factor, value factor, and their implication for excess stock returns and portfolio returns—were estimated on …

Intro To R/Rstudio, John Connolly

Day Family Research Lab Workshop Series

No abstract provided.

Advocating For Social Justice In 4th Grade Ela Curriculum And Standards: Culturally Responsive Fidelity Frameworks For Leadership And Educators, Sélah F. Mcclain

School of Education and Leadership Student Capstone Projects

This Capstone Project examines how the alignment of Minnesota English Language Arts standards and curriculum merged with a culturally responsive teaching fidelity framework will influence student engagement, academic rigor, and intentional academic discourse among Black fourth-grade scholars in an urban learning community. It is grounded in Ladson-Billings’(1995) and (2009) culturally relevant pedagogy, Hammond’s (2021) culturally responsive teaching with connection to the science of learning and development, as well as Falk and Blumenreich’s (2005) theory regarding cognitive constructivism. This research explores the role of leadership and educators in the implementation of culturally responsive pedagogy with fidelity to create coherence between standards, …

Teaching With Nature: Place-Based Learning And Outdoor Education Toward Healing In The K-2 Setting, Isaac Hart

School of Education and Leadership Student Capstone Projects

Outdoor education and place-based learning hold rich histories and futures. This project at large set out to explore the stories and possibilities of outdoor education and place-based learning within the K-2 landscape. The research question being addressed in this project is: How can we use meaningful place-based learning and outdoor education in the K-2 setting as a means of healing relationships with schooling and with the rest of the natural world? Through personal and professional framing, an exploratory literature review, an educator resource toolkit project, and a reflective conclusion, this work presents outdoor education and place-based learning as having myriad …

Criminal Court's Disability, Zohra Ahmed

Faculty Scholarship

Do criminal courts meaningfully accommodate psychiatric disability? A review of competency proceedings across the United States suggests not. In competency to stand trial proceedings, criminal court actors offer a narrow vision of psychiatric disability that excludes many defendants. Ultimately, the institutional context of criminal court undermines even the meagre accommodations that the competency framework provides.

Competency proceedings are the constitutional accommodations available to disabled defendants if they can establish that they are unable to consult with their lawyers or if they do not have a rational or factual understanding of the proceedings against them. After a finding of incompetency, the …

Reasoning From Injustice, Robert L. Tsai

Faculty Scholarship

In a series of lectures at Yale Law School, the Harvard political theorist Judith Shklar critiqued leading models of justice as overly abstract and lacking a realistic account of the social dynamics that perpetuate injustice. In this essay, Professor Tsai builds on Shklar’s account of injustice as a social phenomenon by offering a structural reading of key literary texts that explore the nature of legal injustice—from the Book of Job to Harriett Beecher Stowe’s Uncle Tom’s Cabin and Frederick Douglass’s The Heroic Slave. A close reading of these texts permits us to flesh out Shklar’s observations and “give injustice …

Fall 2025, John M. Pfau Library

Peacock – John M. Pfau Library Newsletter

In this Issue:

• From Tokyo to California pgs. 1 & 2
• Congratulations, Dr. Higgins! p. 2
• More Than 100,000 Streaming Videos p. 2
• CSUSB Libraries Launch Digital Exhibits pgs. 3 & 4
• Guest Speaker Author of Banned Graphic Novel p. 4
• The Thesis Digitization Project is Complete! p. 5
• Chess Club Tournament pgs. 6 & 7
• Banned Books in Library History p. 7
• New Databases pgs. 8 & 9
• Classifieds With Books p. 9

Adapting To Inflationary Pressures: Household Coping Strategies In Urban Egypt (2016– 2025), Mohamed Mohamed Ashraf Kamal

Theses and Dissertations

Over the past decade, Egypt has faced persistent economic challenges including repeated currency devaluations, high inflation rates, subsidy reforms such as the gradual reduction of food and energy subsidies, and the ripple effects of global crises that have significantly impacted household well-being, especially in urban areas. These pressures have eroded purchasing power and heightened food insecurity, especially among low- and middle-income families. Although substantial attention has been paid to macroeconomic indicators, there remains a critical gap in understanding how households adapt on a daily basis to manage financial stress and sustain their livelihoods. This inquiry is especially timely, as household …

Legal Guide For New Hampshire Agricultural Producers, Updated 2025, Seth Wilner

UNH Cooperative Extension

No abstract provided.

Strengthening Connections: Downtowns & Trails In Barrington, Nh, Shannon Rogers Ph.D., Nathaniel B. Bernitz, Patricia Prescott

UNH Cooperative Extension

No abstract provided.

The Mandate For Accountability And The Rule Of Law: A Theological-Ethical Analysis Of The House Of Representatives’ Role After Duterte V. House Of Representatives, Kerr Nell S. Deliva

Loyola Papers

This article offers a theological-ethical analysis of Duterte v. House of Representatives, interpreting the tension between the House of Representatives of the Philippines and the Supreme Court of the Philippines as a kairos that clarifies their institutional vocations. It examines impeachment as a moral duty rooted in popular sovereignty and public accountability, while highlighting challenges to fides publica arising from judicial intervention. Drawing on moral theology, the article underscores the need to balance justice and legal order, proposing pathways for responsible governance and deeper civic engagement.

Paraconsistent Logic And The Metaphysics Of The Incarnation: A Defense Of Jc Beall’S Contradictory Christology, Vincent Ray M. Daut

Loyola Papers

This article explores the application of paraconsistent logic to one of theology’s enduring challenges: the metaphysics of the Incarnation. The claim that Christ is both fully human and fully divine, as defined by the Council of Chalcedon, presents a significant ontological dilemma, as these two natures are inherently incompatible and mutually exclusive according to classical logic: on the one hand, human nature is defined by finitude, mutability, and moral fallibility, and divine nature is understood as infinite, immutable, and morally impeccable, on the other. Drawing on Jc Beall’s contradictory Christology, this article argues that paraconsistent logic provides a coherent framework …

In Praise Of Limits: A Reading Of The Creation Accounts, Lorenzo Zura

Loyola Papers

This paper critiques the modern culture of omnipotence that equates power with limitless freedom, arguing instead that limits are essential for life’s flourishing. Drawing on the biblical narrative—especially Book of Genesis—it presents God not as dominating but self-limiting, as seen in creation and Shabbat. Through key texts, it reinterprets limits as enabling human fulfillment and reframes “original sin” within this perspective, proposing limitation as a foundational condition for authentic life.