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A Global Agenda For Advancing Freshwater Biodiversity Research, Alain Maasri, Sonja C. Jähnig, Hendrik Freitag, 93 Co-Authors Dec 2021

A Global Agenda For Advancing Freshwater Biodiversity Research, Alain Maasri, Sonja C. Jähnig, Hendrik Freitag, 93 Co-Authors

Biology Faculty Publications

Global freshwater biodiversity is declining dramatically, and meeting the challenges of this crisis requires bold goals and the mobilisation of substantial resources. While the reasons are varied, investments in both research and conservation of freshwater biodiversity lag far behind those in the terrestrial and marine realms. Inspired by a global consultation, we identify 15 pressing priority needs, grouped into five research areas, in an effort to support informed stewardship of freshwater biodiversity. The proposed agenda aims to advance freshwater biodiversity research globally as a critical step in improving coordinated actions towards its sustainable management and conservation.


Translating Particulate Hexavalent Chomium-Induced Chromosome Instability, Loss Of Homologous Recombination Repair And Targeting Of Rad51 From Human Lung Fibroblasts To Human Bronchial Epithelial Cells., Idoia Meaza Isusi Dec 2021

Translating Particulate Hexavalent Chomium-Induced Chromosome Instability, Loss Of Homologous Recombination Repair And Targeting Of Rad51 From Human Lung Fibroblasts To Human Bronchial Epithelial Cells., Idoia Meaza Isusi

Electronic Theses and Dissertations

Particulate hexavalent chromium [Cr(VI)] is a well-established human lung carcinogen. RAD51, a key protein in homologous recombination repair pathway, is inhibited after prolonged exposure to Cr(VI), leading to an increase in chromosome instability after prolonged exposures in human lung fibroblasts. chromosome instability is the proposed driver of Cr(VI) carcinogenesis. Since tumors from chromate workers develop from epithelial cells, we sought to translate these findings from human bronchial fibroblasts to human bronchial epithelial cells. We hypothesized Cr(VI) inhibits RAD51 after prolonged exposure leading to an increase in chromosome instability in human bronchial epithelial cells (BEP2D). We characterized the cytotoxicity and measured …


Part-Time., Anthony Mark Piedmonte Dec 2021

Part-Time., Anthony Mark Piedmonte

Electronic Theses and Dissertations

This thesis is a creative writing project in prose covering the first 70 pages of a novel manuscript titled Part-time. Part-time will center around a 25-year-old medical school dropout starting a new job at a neighborhood golf clubhouse and gym. This coming-of-age narrative follows Danny as he struggles with his sexual identity, student debt, and job outlook after returning to the privileged community he grew up in. This sample will introduce the major characters, the clubhouse setting, and the forming relationship dynamics. By the end of these pages, readers will gain insight into how the part-time employees of the Longwood …


Charting The Unknown: Examining The Prevalence And Correlates Of Seconday Traumatic Stress In Kentucky Probation And Parole Officers., Amanda Marie Roberts Dec 2021

Charting The Unknown: Examining The Prevalence And Correlates Of Seconday Traumatic Stress In Kentucky Probation And Parole Officers., Amanda Marie Roberts

Electronic Theses and Dissertations

The purpose of this dissertation was to discern the prevalence and magnitude of both exposure to traumatic events and Secondary Traumatic Stress (STS); as well as potential correlates of STS in a group of Probation and Parole officers in the state of Kentucky Department of Corrections (KY DOC). Participants (N=302) completed a written survey which asked them to indicate demographic variables (age, gender, and ethnicity), as well as several important occupational variables, namely years of experience in the KY DOC, caseload volume, prison work experience, and whether or not they are responsible for a sexual offender caseload. Participants were also …


Social Disorganization And Violent Crime Across Nonmetropolitan Areas Of Kentucky., Daniel Ray Jude Dec 2021

Social Disorganization And Violent Crime Across Nonmetropolitan Areas Of Kentucky., Daniel Ray Jude

Electronic Theses and Dissertations

This macro-level study examines the effects of social disorganization predictors on violent crime registered in nonmetropolitan areas of Kentucky from 2012 to 2016. The study intends to expand the line of research interested in verifying the applicability of the social disorganization theory (Shaw & McKay, 1942), including its new theoretical developments, to non-urban settings and plans to contribute to the literature willing to provide a better understanding of violent crime in rural areas. In response to Narag et al.’s (2009) call for a theoretical integration of environmental contaminants among the ecological factors that influence variations in crime, the study also …


A Remote Sensing Perspective: Mapping The Human Footprint In The Zambezi Region Of Namibia., Ariel E Weaver Dec 2021

A Remote Sensing Perspective: Mapping The Human Footprint In The Zambezi Region Of Namibia., Ariel E Weaver

Electronic Theses and Dissertations

The “human footprint” can be used as a general proxy to estimate human activities across the landscape. The human footprint in the Zambezi Region of Namibia is critically important for regional management of conservation efforts and land use planning. The land covers in the Zambezi Region are characteristically difficult to separate spectrally, due to a highly heterogeneous savanna landscape. Object Based Image Analysis (OBIA) and Random Forest (RF) methods are notable for their ability to improve classification accuracies of remotely sensed imagery. In this study, I investigate the extent of the human footprint in the Zambezi Region of Namibia, using …


Visualizing Anhydrobiosis: Liquid-Liquid Phase Separation, Membraneless Organelles, And Cellular Reorganization., Clinton J. Belott Dec 2021

Visualizing Anhydrobiosis: Liquid-Liquid Phase Separation, Membraneless Organelles, And Cellular Reorganization., Clinton J. Belott

Electronic Theses and Dissertations

Water is an integral and necessary component of life. It is then, exceedingly remarkable that some species are capable of surviving virtually complete water loss for extended periods of time. Several decades of intense research into anhydrobiosis, or life without water, have given significant insights into the molecular mechanisms governing this phenomenon. Anhydrobiosis-related intrinsically disordered (ARID) proteins have been demonstrated to be critically important for desiccation tolerance in many anhydrobiotic species and exhibit a considerably wide range of protective properties that include membrane stabilization, reinforcing bioglass formation, and protein stabilization. This dissertation begins with cellular dielectrophoresis suggesting that two ARID …


Q-Griffithsin Interactions And Utility For The Prevention And Treatment Of Mucosal Infections., Henry Nabeta Dec 2021

Q-Griffithsin Interactions And Utility For The Prevention And Treatment Of Mucosal Infections., Henry Nabeta

Electronic Theses and Dissertations

Griffithsin (GRFT) is a carbohydrate binding agent (lectin) that was originally identified in the red alga Griffithsia sp. Q-Griffithsin (Q-GRFT) is an oxidation stable analog of GRFT. GRFT has demonstrated inhibitory activity against HIV-1, Coronaviruses, Hepatitis C, influenza and Ebola viruses. The broad-spectrum activity suggests the potential utility of this lectin in a wide range of viral infections. However, the lectin’s activity in mucosal infections has not been extensively studied. Using in vitro, ex vivo and in vivo assays, we have demonstrated that Q-GRFT maintains the ability to bind glycosylated ligands following incubation in murine, macaque and human rectal …


An Exploration Of Afrocentric Features At A Black Homeschool Collective., Tytianna Nikia Maria Wells Dec 2021

An Exploration Of Afrocentric Features At A Black Homeschool Collective., Tytianna Nikia Maria Wells

Electronic Theses and Dissertations

This dissertation explores the development and benefits of familial relationships as the primary feature of Afrocentricity at Black Scholars Academy (BSA), a Pre-Kindergarten (Pre-K) through 12th-grade Black homeschool collective in the United States. This qualitative study draws upon Afrocentricity as a theoretical framework to analyze and interpret data collected from classroom observations, individual interviews with current and former teachers and students, and textual artifacts between July and November 2019. Familial relationships—an African time orientation, a personalized learning plan, OurStory, and Rising Meeting—are present in BSA. Familial relationships helped students develop cultural pride, agency, self-determination, independence, liberation through education, and a …


Effects Of Chemosensory Experience And Context On Consummatory Behaviors., Saphira M. Chiu Dec 2021

Effects Of Chemosensory Experience And Context On Consummatory Behaviors., Saphira M. Chiu

Electronic Theses and Dissertations

Eating food generates associations between odors and tastes (i.e., flavor) that guide future choices. Experience with an odor-taste mixture links an odor with a taste’s quality and hedonic value, resulting in a preference for an odor paired with a palatable taste over an odor paired with an unpalatable taste. However, experience with a neutral stimulus (i.e., latent inhibition) or environment (i.e., context) can influence the formation of conditioned associations. Here, I used a two-bottle brief-access task to determine whether rats display an innate preference between unpaired odors (isoamyl acetate and benzaldehyde), how preexposure to the unpaired odors impacts mixture-dependent consummatory …


Theoretical Investigation Of The Co-C Bond Activation In Methylcobalamin And Adenosylcobalamin-Dependent Systems: Mechanistic Insights., Arghya Pratim Ghosh Dec 2021

Theoretical Investigation Of The Co-C Bond Activation In Methylcobalamin And Adenosylcobalamin-Dependent Systems: Mechanistic Insights., Arghya Pratim Ghosh

Electronic Theses and Dissertations

The vitamin B12 derivates, otherwise known as cobalamin (Cbl), are ubiquitous organometallic cofactors. The biologically active forms of Cbl, such as methylcobalamin (MeCbl) and adenosylcobalamin (AdoCbl), act as cofactors in different physiological reactions for both prokaryotes and eukaryotes. A crucial aspect of the Cbl-mediated systems is the activation of the organometallic Co-C bond that plays a critical role in its catalytic activity. One of the most remarkable features of this Co-C bond is its unusual activation in AdoCbl-dependent enzymatic reactions, where a trillion-fold rate acceleration of the Co-C bond cleavage is observed inside the enzyme compared to the isolated …


Boxed In: Hinge Closing Performance Of Ornate Box Turtles (Terrapene Ornata), Gina L. Buelow Dec 2021

Boxed In: Hinge Closing Performance Of Ornate Box Turtles (Terrapene Ornata), Gina L. Buelow

Graduate Theses/Dissertations

Turtles are perhaps best known for the bony shells that encase them, a unique morphological trait that provides protection against predators. Many taxa have even evolved the ability to enclose themselves using hinges that can be used to create a seal between the carapace and plastron. I measured the hinge closing force of Ornate Box Turtles (Terrapene ornata) to assess the performance of this unusual yet ecologically important trait. I sampled head-started turtles from Thomson Sand Prairie in the Upper Mississippi River National Wildlife and Fish Refuge and wild turtles collected in northern Oklahoma. To assess the effects of head-starting …


Effects Of "Lemongrass Factor" On Galleria Mellonella Hemocytes, Jennifer C. Rice Dec 2021

Effects Of "Lemongrass Factor" On Galleria Mellonella Hemocytes, Jennifer C. Rice

Graduate Theses/Dissertations

The use of conventional chemical insecticides to control agricultural pest has become problematic as they may have a negative impact towards human health and the environment, resulting in a need to research alternative methods to insect pest control. Plant derived substances like essential oils have been used for generations as toxicants, repellants, and anti-feedants to control agricultural pest. More research is needed to understand how insect immune systems react to essential oils and if cellular immune responses of phagocytosis, encapsulation, and nodulation can be inhibited by such. Subjecting Galleria mellonella to various concentrations of “lemongrass factor” lets the researcher/scientist know …


A Christian Response To Modern Extraterrestrialism, Chase Perry Cakmis Dec 2021

A Christian Response To Modern Extraterrestrialism, Chase Perry Cakmis

Masters Theses

Extraterrestrial beliefs (ET-ism) have become a cultural craze in contemporary times, infatuating many who encounter these ideas. ET-ism has influenced all forms of media, science, and even religion. With ET-ism permeating all facets of society, Christians need to know how to approach this craze and the ideas that sprout from it. Much research has been conducted on this subject both on the individual and scientific level, thrusting these beliefs from fringe views believed only by the paranoid into widely accepted ideas even within the scientific community. While Christian circles have discussed this subject in the past, it is becoming a …


Traversing The Back Door Of The Mind: Directing Imaginative Stories To Generate Meaningful Dialogue About Biblical Truths In A Materialist World, Heather Jean Birkeland Dec 2021

Traversing The Back Door Of The Mind: Directing Imaginative Stories To Generate Meaningful Dialogue About Biblical Truths In A Materialist World, Heather Jean Birkeland

Masters Theses

Ontological materialism hinders evangelistic efforts because it precludes any dialogue about spiritual matters, especially regarding the importance of cultivating an eternal value system. Furthermore, potential meaningful dialogue is inhibited by an audience that routinely rejects overtly Christian materials, which results in failure to develop the correct contextual understanding regarding biblical spiritual truths. The writer provides an overview of the philosophy of ontological materialism and its effects on people, the impact of imaginative storytelling, and the psychology of narrative persuasion. Firstly, the selected thesis topic will explore how non-Christians could potentially approach and engage in biblical truths without hostility through the …


The Supporting Role: Cultivating A Writing Life To Prevent And Combat Writer's Block, Molly Elizabeth Hanberry Dec 2021

The Supporting Role: Cultivating A Writing Life To Prevent And Combat Writer's Block, Molly Elizabeth Hanberry

Masters Theses

Every writer will suffer from writer’s block from time to time, and there are two general schools of thought in dealing with this affliction: wait it out or struggle through. The purpose of this thesis is to illuminate the nature of writer’s block from a fundamental level, beginning with the neuroscience of creativity. From there, it will explore the three root causes of writer’s block: lack of inspiration, burnout, and fear. And finally, with an understanding of its causes, it will be possible to examine ways to combat writer’s block through methods based in neuroscience, personal experience, and professional advice …


Modulation Of Stress-Induced Behaviors Through Orexinergic Signaling In The Basolateral Amygdala, Jazmine D W Yaeger Dec 2021

Modulation Of Stress-Induced Behaviors Through Orexinergic Signaling In The Basolateral Amygdala, Jazmine D W Yaeger

Dissertations and Theses

Stress initiates behavioral disturbances, which are often seen as symptoms of psychiatric disorders, like post-traumatic stress disorder (PTSD), depression, and anxiety. While stress is involved in the formation of disordered states, only certain individuals are vulnerable to, and therefore experience, these outcomes. Further, females are more likely to be diagnosed with stress-induced psychiatric disorders. Elements within stress neurocircuitry offer insight into differential behavioral outcomes associated with stressful experiences; and the basolateral amygdala (BLA), where pro- and anti-stress signals are integrated, is likely an important mediator in phenotype development. The orexin system, too, while being strongly associated with sleep, motivation, and …


Combination Intrathecal Drug Therapy Strategies For Pain Management, Jay Karri, Mani Singh, Devas J Modi, Vwaire Orhurhu, Caleb Seale, Michael Saulino, Anuj Marathe, Darrell Vydra, Jonathan M Hagedorn, Brian Bruel, Alaa Abd-Elsayed Dec 2021

Combination Intrathecal Drug Therapy Strategies For Pain Management, Jay Karri, Mani Singh, Devas J Modi, Vwaire Orhurhu, Caleb Seale, Michael Saulino, Anuj Marathe, Darrell Vydra, Jonathan M Hagedorn, Brian Bruel, Alaa Abd-Elsayed

Department of Rehabilitation Medicine Faculty Papers

Background: Numerous combination intrathecal drug therapy (CIDT) strategies exist and are utilized for varying pain syndromes, typically when monotherapy dose escalation or medication alternation is deemed untenable or unfeasible. Unfortunately, the supportive evidence basis for the use of these strategies and specific drug combinations is generally lacking and unclear, with many medications being used for off-label indications.

Objective: In this manuscript, we provide a robust exploration and analysis of the literature to provide an evidence-based narrative for the use of CIDT strategies in regard to clinical indications, pharmacologic parameters, specific drug combinations, safety profiles, and future directions.

Study design: Narrative …


Human Behavior In Domestic Environments: Prediction And Applications, Sharare Zehtabian Dec 2021

Human Behavior In Domestic Environments: Prediction And Applications, Sharare Zehtabian

Electronic Theses and Dissertations, 2020-2023

A longstanding goal of human behavior science is to model and predict how humans interact with each other or with other systems. Such models are beneficial and have many applications, including designing and implementing assistive technologies, improving users' experiences and quality of life and making better decisions to create public policies. Behavior is highly complex due to uncertainties and a lack of scientific tools to measure it. Hence prediction of human behavior cannot be 100% accurate. However, prediction is also not hopeless because the biological needs, as well as cultural conventions (for instance, regarding meal times) set the general patterns …


Forage News [2021-12], Department Of Plant And Soil Sciences, University Of Kentucky Dec 2021

Forage News [2021-12], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

No abstract provided.


The Mayfly Newsletter, Donna Giberson Dec 2021

The Mayfly Newsletter, Donna Giberson

The Mayfly Newsletter

The Mayfly Newsletter is the official newsletter of the Permanent Committee of the International Conferences on Ephemeroptera.


Discriminatory Permissions And Structural Injustice, Lawrence G. Sager, Nelson Tebbe Dec 2021

Discriminatory Permissions And Structural Injustice, Lawrence G. Sager, Nelson Tebbe

Minnesota Law Review Vols. 106:2 onward (2021-present)

America is engaged in a nationwide conversation about conscience exemptions from equality laws. So far, that conflict has been debated in terms of religious liberty. Courts have asked whether religious actors like Hobby Lobby and Masterpiece Cakeshop are entitled to exemptions from civil rights laws and whether any such exemptions count as establishments of religion. This framing overlooks an important issue, namely whether any such exemptions violate the Equal Protection Clause. In this Article, we argue that explicit state enactments that both permit and encourage private discrimination against people subject to structural injustice can and should be invalidated by judges …


Iron Geochemistry Across An Estuary-To-Coastal Gradient, Lissett G. Diaz Dec 2021

Iron Geochemistry Across An Estuary-To-Coastal Gradient, Lissett G. Diaz

Honors Theses

Iron is a ubiquitous earth element that participates in biogeochemical processes that occur in marine sediments. Microorganisms utilize iron for many purposes, including cell growth, conserving energy, and for maintaining metabolic activity. In coastal sedimentary settings, understanding the redox reactions involving ferric iron, Fe3+, and ferrous iron, Fe2+, in its solid phase and pore-water phases, respectively, enable an appreciation of biogeochemical transformations occurring in the coastal zone. In this study, iron concentrations in sediment of ranging permeability were determined at four stations marking an estuary-coast transition zone in Singleton Swash in Myrtle Beach, South Carolina. The …


Representation, Resistance, And Recovery: Cultural Trauma In Young Adult Literature, Perla Rodriguez Dec 2021

Representation, Resistance, And Recovery: Cultural Trauma In Young Adult Literature, Perla Rodriguez

McNair Scholars Research Journal

No abstract provided.


God And Kant’S Suicide Maxim, Carlo Alvaro Dec 2021

God And Kant’S Suicide Maxim, Carlo Alvaro

Publications and Research

Kant’s argument against suicide is widely dismissed by scholars and often avoided by teachers because it is deemed inconsistent with Kant’s moral philosophy. This paper attempts to show a way to make sense of Kant’s injunction against suicide that is consistent with his moral system. One of the strategies adopted in order to accomplish my goal is a de-secularization of Kant’s ethics. I argue that all actions of self-killing (or suicide) are morally impermissible because they are inconsistent with God’s established nature and order. It is argued that the existence of God as the locus of moral value and duty …


Toxicity And Effects Of Tire Crumb Rubber In The Aquatic Environment, Stephanie Laplaca Dec 2021

Toxicity And Effects Of Tire Crumb Rubber In The Aquatic Environment, Stephanie Laplaca

All Dissertations

Plastic materials have provided innovative solutions to society’s evolving needs and challenges. Due to their durability and resistance to degradation, plastics remain in the environment for long periods of time and can therefore be transported to many environmental compartments such as water, sediment, and biota. Microplastics (MPs) have been defined as synthetic plastic particles that have at least one dimension less than 5 mm and are insoluble in water. Microrubber (MR), a recently acknowledged sub-group of MPs, has been documented in environmental samples more recently, frequently comprising a large portion of total MPs of various samples. In South Carolina specifically, …


Index To Volume 89 Dec 2021

Index To Volume 89

Nebraska Bird Review

Adams, Marie 52

to

Zonotrichia leucophrys gambelii 168 leucophrys 75, 168-169 oriantha 75, 169


Review Of The Sandhill Crane State: A Naturalist’S Guide To Nebraska By Paul Johnsgard, Ruth Stearns Dec 2021

Review Of The Sandhill Crane State: A Naturalist’S Guide To Nebraska By Paul Johnsgard, Ruth Stearns

Nebraska Bird Review

Dr. Paul Austin Johnsgard left us one last gift, in this reference guide to all places natural in Nebraska. Published posthumously, and available for purchase or free via UNL’s Digital Commons, this book arrived at my doorstep like a veritable “seed catalog” of Nebraska’s places of wonder to delight and inspire fair weather adventures just before the long winter set in. He wants us to explore the state as he had done, to be excited by all the out-ofdoors Nebraska has to offer.


Northern Saw-Whet Owl Autumn Migration In Eastern Nebraska: Results From A Three-Year Banding Study, Stephen J. Brenner, Joel G. Jorgensen Dec 2021

Northern Saw-Whet Owl Autumn Migration In Eastern Nebraska: Results From A Three-Year Banding Study, Stephen J. Brenner, Joel G. Jorgensen

Nebraska Bird Review

Prior to 2019, records of NSWOs in Nebraska during fall were limited. There were fewer than five accepted reports in eastern Nebraska since the 1950s (Silcock and Jorgensen, 2021). The Hitchcock banding station along the Missouri River bluffs in nearby western Iowa has captured, banded, and released 20-50 birds during autumn migration for a number of years (J. Toll, personal communication). Furthermore, a single season banding study in central Nebraska during fall 2004 captured 14 NSWOs (Kim 2005), suggesting the species may migrate annually over much of the state in fall, or at least in more years than previously thought. …


Review Of Nest Records Of Nebraska Birds By Wayne J. Mollhoff, W. Ross Silcock Dec 2021

Review Of Nest Records Of Nebraska Birds By Wayne J. Mollhoff, W. Ross Silcock

Nebraska Bird Review

This book summarizes a lifetime of investigation of Nebraska’s breeding birds by Wayne Mollhoff. Even though I say the book summarizes a lifetime of investigation, I would not be surprised if Wayne resurfaces in a few years with a follow-up of some sort, intrepid investigator that he is. Over the years Wayne has spent innumerable days in the field climbing trees in full forestry gear, wading and kayaking marshes and rivers, hiking over prairies, and bushwhacking through dense forests (there are still a few in Nebraska). But this isn’t the totality of Wayne’s talents; he is a determined researcher with …