Digital Commons Network^™

Voicing Derbarl Yerrigan As A Feminist Anti-Colonial Methodology, Vanessa Wintoneak, Mindy Blaise

Research outputs 2014 to 2021

The paper voices Derbarl Yerrigan, a significant river in Western Australia, through three imperfect, non-innocent, and necessary river-child stories. These stories highlight the emergence of a feminist anti-colonial methodology that is attentive to settler response-abilities to Derbarl Yerrigan through situated, relational, active, and generative research methods. Voicing Derbarl Yerrigan influences the methodological practices used as part of an ongoing river-child walking inquiry that is concerned with generating climate change pedagogies in response to the global climate crises and calls for new ways of thinking and producing knowledge. In particular, the authors found that voicing as a methodology includes listening and …

Promoting Awareness Of Sex Trafficking In Tourism And Hospitality, Joshua Aston, Jun Wen, Edmund Goh, Oswin Maurer

Research outputs 2014 to 2021

Purpose: This cutting-edge short commentary is intended to raise awareness of sex trafficking in the tourism and hospitality industry. The purpose of this paper is to also advocate for further research to identify and hopefully prevent sex trafficking in related settings.

Design/methodology/approach: This paper provides a descriptive overview of the current knowledge base on sex trafficking in tourism and hospitality. Based on gaps in the literature, future research agendas and directions are suggested.

Findings: Academic research on sex trafficking in tourism and hospitality remains limited. More scholarly attention is needed to this matter. The tourism industry is directly and indirectly …

Animal Source Foods, Rich In Essential Amino Acids, Are Important For Linear Growth And Development Of Young Children In Low- And Middle-Income Countries, Panam Parikh, Richard Semba, Mark Manary, Sumathi Swaminathan, Emorn Udomkesmalee, Rolf Bos, Bee Koon Poh, Nipa Rojroongwasinkul, Jan Geurts, Rini Sekartini, Tran Thuy Nga

2020-Current year OA Pubs

Growth faltering under 5 years of age is unacceptably high worldwide, and even more children, while not stunted, fail to reach their growth potential. The time between conception and 2 years of age is critical for development. The period from 6 to 23 months, when complementary foods are introduced, coincides with a time when growth faltering and delayed neurocognitive developments are most common. Fortunately, this is also the period when diet exercises its greatest influence. Growing up in an adverse environment, with a deficient diet, as typically seen in low- and middle-income countries (LMICs), hampers growth and development of children …

More Amazon Than Mafia: Analysing A Ddos Stresser Service As Organised Cybercrime, Roberto Musotto, David S. Wall

Research outputs 2014 to 2021

© 2020, The Author(s). The internet mafia trope has shaped our knowledge about organised crime groups online, yet the evidence is largely speculative and the logic often flawed. This paper adds to current knowledge by exploring the development, operation and demise of an online criminal group as a case study. In this article we analyse a DDoS (Distributed Denial of Service) stresser (also known as booter) which sells its services online to enable offenders to launch attacks. Using Social Network Analysis to explore the service operations and payment systems, our findings show a central business model that is similar to …

Sulfur Compounds: From Plants To Humans And Their Role In Chronic Disease Prevention, Caroline R. Hill, Armaghan Shafaei, Lois Balmer, Joshua R. Lewis, Jonathan M. Hodgson, A. Harvey Millar, Lauren C. Blekkenhorst

Research outputs 2022 to 2026

Sulfur is essential for the health of plants and is an indispensable dietary component for human health and disease prevention. Its incorporation into our food supply is heavily reliant upon the uptake of sulfur into plant tissue and our subsequent intake. Dietary requirements for sulfur are largely calculated based upon requirements for the sulfur-containing amino acids (SAA), cysteine and methionine, to meet the demands for synthesis of proteins, enzymes, co-enzymes, vitamins, and hormones. SAA are found in abundance in animal sources and are relatively low in plants. However, some plants, particularly cruciferous and allium vegetables, produce many protective sulfur-containing secondary …

Identifying Effective Interventions To Promote Consumption Of Protein-Rich Foods From Lower Ecological Footprint Sources: A Systematic Literature Review, Rimante Ronto, Golsa Saberi, Gianna Maxi Leila Robbers, Stephanie Godrich, Mark Lawrence, Shawn Somerset, Jessica Fanzo, Josephine Chau

Research outputs 2022 to 2026

Addressing overconsumption of protein-rich foods from high ecological footprint sources can have positive impacts on health such as reduction of non-communicable disease risk and protecting the natural environment. With the increased attention towards development of ecologically sustainable diets, this systematic review aimed to critically review literature on effectiveness of those interventions aiming to promote protein-rich foods from lower ecological footprint sources. Five electronic databases (Medline, Web of Science, Scopus, Embase and Global Health) were searched for articles published up to January 2021. Quantitative studies were eligible for inclusion if they reported on actual or intended consumption of protein-rich animal-derived and/or …

Impact Of Supply Chain Integration On Halal Food Supply Chain Integrity And Food Quality Performance, Mohd Helmi Ali, Mohammad Iranmanesh, Kim Hua Tan, Suhaiza Zailani, Nor Asiah Omar

Research outputs 2014 to 2021

Purpose: The current complex halal food supply chain (SC) has caused food scandals, which have illustrated the weakness of multiple food quality standards and certification and audits in ensuring food safety. Drawn on the resource-based view (RBV) theory, the purpose of this study is to explore the impacts of SC integration (SCI) on halal food SC integrity and, consequently, food quality.

Design/methodology/approach: Empirical data were collected from 275 halal-certified food companies in Malaysia and analysed using structural equation modelling – SmartPLS3.0.

Findings: The results confirmed that SCI, including internal, supplier and customer integrations, has significant effects on the dimensions of …

A Myc-Znf148-Id1/3 Regulatory Axis Modulating Cancer Stem Cell Traits In Aggressive Breast Cancer, Mijeong Kim, Manjot Singh, Bum-Kyu Lee, Moira Hibbs, Kirsty Richardson, Lesley Ellies, Larissa Wintle, Lisa M. Stuart, Jenny Y. Wang, Dominic C. Voon, Pilar Blancafort, Jianlong Wang, Jonghwan Kim, Peter J. Leedman, Andrew J. Woo

Research outputs 2022 to 2026

The MYC proto-oncogene (MYC) is one of the most frequently overexpressed genes in breast cancer that drives cancer stem cell-like traits, resulting in aggressive disease progression and poor prognosis. In this study, we identified zinc finger transcription factor 148 (ZNF148, also called Zfp148 and ZBP-89) as a direct target of MYC. ZNF148 suppressed cell proliferation and migration and was transcriptionally repressed by MYC in breast cancer. Depletion of ZNF148 by short hairpin RNA (shRNA) and CRISPR/Cas9 increased triple-negative breast cancer (TNBC) cell proliferation and migration. Global transcriptome and chromatin occupancy analyses of ZNF148 revealed a central role in inhibiting cancer …

Associations Of The Lipidome With Ageing, Cognitive Decline And Exercise Behaviours, Maria Kadyrov, Luke Whiley, Belinda Brown, Kirk I. Erickson, Elaine Holmes

Research outputs 2022 to 2026

One of the most recognisable features of ageing is a decline in brain health and cognitive dysfunction, which is associated with perturbations to regular lipid homeostasis. Although ageing is the largest risk factor for several neurodegenerative diseases such as dementia, a loss in cognitive function is commonly observed in adults over the age of 65. Despite the prevalence of normal age-related cognitive decline, there is a lack of effective methods to improve the health of the ageing brain. In light of this, exercise has shown promise for positively influencing neurocognitive health and associated lipid profiles. This review summarises age-related changes …

Exploring Food Supply Chain Trends In The Covid-19 Era: A Bibliometric Review, Abderahman Rejeb, Karim Rejeb, Andrea Appolloni, Mohammad Iranmanesh, Horst Treiblmaier, Sandeep Jagtap

Research outputs 2022 to 2026

Recently, the food supply chain (FSC) has been severely disrupted due to the COVID-19 pandemic, putting the vital flow of food products from farmers and producers to the ultimate consumers at risk. Furthermore, due to the pandemic, several food organizations have been prompted to rethink their strategies for the future. Although the literature on FSC research in the COVID-19 era is increasing, no attempt has been made to summarize this stream of research using bibliometric techniques. This paper fills this knowledge gap and looks at the current scholarly discourse around the FSC and COVID-19. Applying bibliometric techniques, 287 journal articles …

World In Strife – Returning To The Humanities, Clive Barstow, Jill Felicity Durey

Research outputs 2022 to 2026

The background of this article relates to a long, ongoing attenuation of the Humanities within universities. The problem is the continuing sidelining of the Humanities in university teaching and research funding. If this attenuation and sidelining continue, the world will be a much more cruel and dangerous place, as there will be no moral or ethical check on scientific and technological developments from a humanitarian perspective. This article discusses some of the fears, hopes and criticisms of the Humanities expressed by scholars around the globe, from western democracies including Australia, as well as from middle-eastern and eastern autocracies. The article …

Deep Learning Inspired Feature Engineering For Classifying Tremor Severity, Ahmed Al Taee, Seyedehmarzieh Hosseini, Rami N. Khushaba, Tanveer Zia, Chin-Teng Lin, Adel Al-Jumaily

Research outputs 2022 to 2026

Bio-signals pattern recognition systems can be impacted by several factors with a potential to limit their associated performance and clinical translation. Among these factors, selecting the optimum feature extraction method, that can effectively exploit the interaction between the temporal and spatial information, is the most prominent. Despite the potential of deep learning (DL) models for extracting temporal, spatial, or temporal-spatial information, they are typically restricted by their need for a large amount of training data. The deep wavelet scattering transform (WST) is a relatively recent advancement within the DL literature to replace expensive convolution neural networks models with computationally less …

Development Of Terminology Of Word-Formation Synthesis. Features Of The Terminological System (Based On The Verbs Of The Sound Of The Russian Language), Irina V. Ivliyeva

Arts, Languages and Philosophy Faculty Research & Creative Works

English Abstract:

The purpose of the research is to present the terminology of word-formation synthesis as an organized system, to identify the stages of development of relevant terms. The scientific novelty of the research lies in the fact that a structured corpus of terms of word-formation synthesis with elements of definitional analysis is introduced into scientific circulation. different stages of research. The system of terms of modification synthesis is applied and studied in practice – in the author's search program for web extraction of verbs of sound from the databases of modern dictionaries and the Russian National Corpus.

Russian Abstract: …

Preclinical Antibody-Pet Imaging Of Pd-L1, Emma L Brown, Rachel A Deweerd, Abbey Zidel, Patricia M R Pereira

2020-Current year OA Pubs

Programmed cell death protein-1/ligand-1 (PD-1/PD-L1) blockade, including antibody therapeutics, has transformed cancer treatment. However, a major challenge in the field relates to selecting patients who are likely to respond to immune checkpoint inhibitors. Indeed, biopsy-based diagnostic tests to determine immune checkpoint protein levels do not accurately capture the inherent spatial and temporal heterogeneity of PD-L1 tumor expression. As a result, not all PD-L1-positive tumors respond to immunotherapies, and some patients with PD-L1-negative tumors have shown clinical benefits. In 2018, a first-in-human study of the clinically-approved anti-PD-L1 antibody Atezolizumab labeled with the positron emitter zirconium-89 validated the ability of positron emission …

Sustainable Food Waste Management Through The Integration Of Anaerobic Digestion And Thermochemical Processes, Diana Carolina Rodriguez Alberto

Theses

The processing of food waste along with animal manure through anaerobic digestion (AD) is a popular waste management strategy. However, there is the concern that with the proliferation of AD the management of its nutrient-rich effluent, known as digestate, becomes a challenge. Current digestate management practices not only present environmental risks, but also issues related to the seasonality of field spreading and the storage and transportation of large volumes of material. The integration of the AD process with thermochemical conversion (TC) could help reduce some of these issues. The production of biochar from materials already available in the digester setting, …

Investigation Of The Users’ Access To Health Information For Sustainable Development During The Covid 19 Era In Professor Kenneth Dike E-Central Library, Awka, Anambra State, Eliezer C. Agim, Maureen Azolo

Library Philosophy and Practice (e-journal)

The research investigated users’ access to health information for sustainable development during the Covid 19 era in Professor Kenneth Dike E-central Library, Awka, Anambra state. A descriptive survey research design was used for the study. The sample population comprised of 100 users of Professor Kenneth Dike E-central Library through the use of accidental sampling technique. A structured questionnaire was used for collection of data. The instrument was subjected to face validation and pilot test using Cronbach Alpha which gave a reliability coefficient value of 0.97. Data collected from the study were analyzed using mean scores. The study found that health …

Rejuvenating Academic Libraries For Effective Service Delivery In The Post Covid-19 Era, Emuejevoke Paul Ogo Mr, Angela Chiwendu Nweke Mrs, Ademola Ferdinand Omosekejimi Mr

Library Philosophy and Practice (e-journal)

This study focused on rejuvenating academic libraries for effective service delivery in the post COVID 19 era. The offering of online services in academic libraries has received attention as a result of the COVID-19 epidemic, with higher educational institutions all across the world adopting this development as the "new normal." The pandemic has posed several difficulties for most universities and its academic libraries, particularly for those with weaker online presence. It however sparked transformation and a re-evaluation of priorities; providing a new purpose for academic libraries that provide information services 24 hours a day. This mission focuses on access and …

Documentation Of Nigerian Indigenous Knowledge System: The Role Of The Library, Christopher Agbeniaru Omigie Dr., Theresa Osasu Makinde Mrs., Ademola Victor Adeniran Mr.

Library Philosophy and Practice (e-journal)

This paper is on documentation of Nigerian indigenous knowledge system (IKS) as a national heritage through the role of the library as catalyst. The paper used literature analysis, recognizance survey and observations to explicitly describe the concept of IKS and its various sustainable ethos; it illustrates the components of the Nigerian IKS including the encompassed spiritual and physical sustainable elements that helps to promote its long time survival. Also treated in the paper are the relevance of IKS to the Nigerian national development; the challenges of IKS development in the country and the role of the library for sustainable collection …

Reconstructing Neural Circuits Using Multiresolution Correlated Light And Electron Microscopy, Karl Friedrichsen, Pratyush Ramakrishna, Jen-Chun Hsiang, Katia Valkova, Daniel Kerschensteiner, Josh L Morgan

2020-Current year OA Pubs

Correlated light and electron microscopy (CLEM) can be used to combine functional and molecular characterizations of neurons with detailed anatomical maps of their synaptic organization. Here we describe a multiresolution approach to CLEM (mrCLEM) that efficiently targets electron microscopy (EM) imaging to optically characterized cells while maintaining optimal tissue preparation for high-throughput EM reconstruction. This approach hinges on the ease with which arrays of sections collected on a solid substrate can be repeatedly imaged at different scales using scanning electron microscopy. We match this multiresolution EM imaging with multiresolution confocal mapping of the aldehyde-fixed tissue. Features visible in lower resolution …

Cgas-Sting Pathway Targeted Therapies And Their Applications In The Treatment Of High-Grade Glioma, Shashwat Tripathi, Hinda Najem, Akanksha Sanjay Mahajan, Peng Zhang, Justin T Low, Alexander H Stegh, Michael A Curran, David M Ashley, Charles David James, Amy B Heimberger

2020-Current year OA Pubs

Median survival of patients with glioblastoma (GBM) treated with standard of care which consists of maximal safe resection of the contrast-enhancing portion of the tumor followed by radiation therapy with concomitant adjuvant temozolomide (TMZ) remains 15 months. The tumor microenvironment (TME) is known to contain immune suppressive myeloid cells with minimal effector T cell infiltration. Stimulator of interferon genes (STING) is an important activator of immune response and results in production of Type 1 interferon and antigen presentation by myeloid cells. This review will discuss important developments in STING agonists, potential biomarkers for STING response, and new combinatorial therapeutic approaches …

Analysis Of Neuronal Injury Transcriptional Response Identifies Ctcf And Yy1 As Co-Operating Factors Regulating Axon Regeneration, Oshri Avraham, Jimmy Le, Kathleen Leahy, Tiandao Li, Guoyan Zhao, Valeria Cavalli

2020-Current year OA Pubs

Injured sensory neurons activate a transcriptional program necessary for robust axon regeneration and eventual target reinnervation. Understanding the transcriptional regulators that govern this axon regenerative response may guide therapeutic strategies to promote axon regeneration in the injured nervous system. Here, we used cultured dorsal root ganglia neurons to identify pro-regenerative transcription factors. Using RNA sequencing, we first characterized this neuronal culture and determined that embryonic day 13.5 DRG (eDRG) neurons cultured for 7 days are similar to e15.5 DRG neurons

Child Dietary Patterns In Homo Sapiens Evolution: A Systematic Review, Lora L Iannotti, Emmanuel A Gyimah, Miranda Reid, Melissa Chapnick, Mary Kate Cartmill, Chessa K Lutter, Charles Hilton, Theresa E Gildner, Elizabeth A Quinn

2020-Current year OA Pubs

Dietary patterns spanning millennia could inform contemporary public health nutrition. Children are largely absent from evidence describing diets throughout human evolution, despite prevalent malnutrition today signaling a potential genome-environment divergence. This systematic review aimed to identify dietary patterns of children ages 6 months to 10 years consumed before the widespread adoption of agriculture. Metrics of mention frequency (counts of food types reported) and food groups (globally standardized categories) were applied to: compare diets across subsistence modes [gatherer-hunter-fisher (GHF), early agriculture (EA) groups]; examine diet quality and diversity; and characterize differences by life course phase and environmental context defined using Köppen-Geiger …

Personalized Practice Dosages May Improve Motor Learning In Older Adults Compared To "Standard Of Care" Practice Dosages: A Randomized Controlled Trial, Geneviève N Olivier, Leland E Dibble, Serene S Paul, Keith R Lohse, Christopher S Walter, Ryan J Marker, Heather A Hayes, K Bo Foreman, Kevin Duff, Sydney Y Schaefer

2020-Current year OA Pubs

Standard dosages of motor practice in clinical physical rehabilitation are insufficient to optimize motor learning, particularly for older patients who often learn at a slower rate than younger patients. Personalized practice dosing (i.e., practicing a task to or beyond one's plateau in performance) may provide a clinically feasible method for determining a dose of practice that is both standardized and individualized, and may improve motor learning. The purpose of this study was to investigate whether personalized practice dosages [

The Use Of Personal Digital Archiving For Effective Learning During Pandemic Covid-19, Naufal Ahmad Rijalul Alam

Library Philosophy and Practice (e-journal)

The Covid 19 pandemic that ravaged the world, particularly Indonesia, had a negative impact on aspects of learning, particularly for children aged three to six years in early childhood education. The implementation of distance learning disrupted the face-to-face learning model, which was supposed to be the primary medium for increasing children's knowledge and interest. In this regard, the role of parents is critical in ensuring that learning at home is effective and enjoyable. This study explores the using personal digital archiving (PDA) conducted by parents for effective learning during pandemic covid-19. By using a case study, this qualitative research took …

Comparative Study For Assessment Of Koha And Slims Features In Public Sector College Libraries Of Sindh, Aijaz Akhter Ahmedani, Khurram Shahzad, Rashid Siddique, Sara Khan

Library Philosophy and Practice (e-journal)

The core aim of the study was to assess KOHA and SLiMS features in Government College Libraries of Sindh. The objectives of the study were (a) to explore the reasons of Koha and SLiMS adoption and (b) to recognize the problems face by library professionals in the implementation of Koha and SLiMS. To meet the objectives, the study used a quantitative research approach and the survey method based on the questionnaire. Purposive sampling technique was used. The data was gathered only from those librarians who were working in Govt Colleges of Karachi, Hyderabad, and Sukkur and were using Koha or …

Homography Of Inventorship: Dabus And Valuing Inventors, Jordana Goodman

Faculty Scholarship

On July 28, 2021, the Device for the Autonomous Bootstrapping of Unified Sentience ("DAB US") became the first computer to be recognized as a patent inventor. Due to the advocacy of DAB US's inventor, Dr. Stephen Thaler, the world's definition of "inventor" has finally fractured - dividing patent regimes between recognition of machine inventorship and lack thereof This division has sparked many scholarly conversations about inventorship contribution, but none have discussed the implications of a homographic inventorship.

This Article addresses the implications of international homographic inventorship - where countries have different notions and rules concerning patent inventorship - and the …

Regulation, Targets And Functions Of Chk, Shudong Zhu, Rong Sun, Xialing Guo, Yuanwu Bao, Dianzheng Zhang

PCOM Scholarly Works

Src family kinases (SFKs) play pivotal roles in multiple signaling pathways (Yeatman, 2004). SFK activity is inhibited by phosphorylation at its C-terminal tyrosine, by CSK (C-terminal Src kinase) and CHK (CSK-homologous kinase). CHK expression is restricted to normal hematopoietic cells, brain, and colon tissues. Downregulation of CHK in brain and colon tumors contributes to tumorigenicity in these tissues. CHK does not phosphorylate Src efficiently, however, in contrast to CSK, CHK inhibits Src kinase activity allosterically. Although the functions of CHK are still largely unknown, potential substrates of CHK including β-synuclein, α-tubulin, α-spectrin, 14-3-3, and Hsp90 have been identified. CHK is …

Teaching Income Inequality With Data-Driven Visualization, Sang T. Truong, Humberto Barreto

School of Business and Leadership Working Papers

The distribution of household income is a central concern in economics due to its strong influence on society’s well-being and social cohesion. Yet, non-expert audiences face serious obstacles in understanding conventional measures of inequality. To effectively communicate the extent of income inequality in the United States, we have developed a novel technique for visualizing income distribution and its dispersion over time by using U.S. household income microdata from the Current Population Survey. The result is a striking dynamic animation of income distribution over time, drawing public attention and encouraging further investigation of income inequality. Detailed implementation is available at https://github.com/sangttruong/incomevis. …

Highlights From International Conference On Cancer Health Disparities 2021, Murali M. Yallapu, Jorge L. Teniente, Andrew Tsin, Subhash C. Chauhan

School of Medicine Publications

The first International Conference on Cancer Health Disparities (ICCHD) was held on August 13-14, 2021, in Harlingen, TX, USA. This two-day ICCHD-2021 was organized by the University of Texas Rio Grande Valley, School of Medicine (UTRGV-SOM). About 200 national and international delegates from 10 countries attended this hybrid meeting in person and through online digital platforms. The event delegates were representatives from National Institutes of Health (NIH), Cancer Prevention and Research Institute of Texas (CPRIT), and the City of Harlingen, in addition to clinicians, faculty, researchers, scientists, bioinformaticians, geneticists, bioethicists, and others. Under the theme of Cancer Health Disparities, this …

Rev-Erb Is Essential In Cardiac Fibroblasts Homeostasis, Xiaokang Luo, Shiyang Song, Lei Qi, Chih-Liang Tien, Hui Li, Weiyi Xu, Theodore Lemuel Mathuram, Thomas Burris, Yuanbiao Zhao, Zheng Sun, Lilei Zhang

Faculty, Staff and Students Publications

REV-ERB agonists have shown antifibrotic effects in the heart and other organs. The function of REV-ERB in the cardiac fibroblasts remains unstudied. Here, we characterize the functional difference of REV-ERB in mouse embryonic fibroblasts and cardiac fibroblasts using genetic deletion of REV-ERBα and ß in vitro. We show that REV-ERB α/β double deleted cardiac fibroblasts have reduced viability and proliferation, but increased migration and myofibroblasts activation. Thus, REV-ERB α/β has essential cell-autonomous role in cardiac fibroblasts in maintaining them in a healthy, quiescent state. We also show that existing REV-ERB agonist SR9009 strongly suppresses cardiac fibroblasts activation but in …