Digital Commons Network^™

Gut Microbiota Diversity And Composition In Predicting Immunotherapy Response And Immunotherapy-Related Colitis In Melanoma Patients: A Systematic Review, Oliver Oey, Yu-Yang Liu, Angela F. Sunjaya, Daniel M. Simadibrata, Muhammad A. Khattak, Elin Gray

Research outputs 2022 to 2026

Background: Gut microbiome (GM) composition and diversity have recently been studied as a biomarker of response to immune checkpoint blockade therapy (ICB) and of ICB-related colitis. Aim: To conduct a systematic review on the role of GM composition and diversity in predicting response and colitis in patients with melanoma treated with ICB. Methods: The review protocol was registered in PROSPERO: CRD42021228018. From a total of 300 studies, nine studies met inclusion criteria. Two studies were phase I clinical trials, while the remainder were prospective observational studies. All but one study has moderate risk of bias. In addition, we conducted a …

Children’S Perspectives Of Digital Citizenship In India, Korea And Australia: Report Of Findings From Children’S Digital Citizenship And Safety Roundtables, Kylie Stevenson, Emma Jayakumar, Harrison See, Yeonghwi Ryu, Shruti Das

Research outputs 2022 to 2026

This report presents data and findings from Phase Two of the research project Digital Safety and Citizenship Roundtables. In this phase, which focuses on children’s perspectives of digital safety and digital citizenship, three child-focused, play-based roundtables were held in Seoul (Korea), Delhi (India) and Perth (Australia) respectively in the months of June and July 2022, with 48 children in total contributing their perspectives. Qualitative data was collected from these child participants through 90-minute play-based roundtables featuring three sections: a short introductory drawing activity using prompt cards; a discussion regarding the children’s understanding of digital citizenship; and a LEGO play activity …

Using Internet Reciprocal Teaching To Develop Second Graders' Online Text Evaluation Skills, Annika Buell

Dissertations and Theses @ UNI

This study was designed to explore the relationship between Internet Reciprocal Teaching (IRT) and young students’ online text evaluation skills. It built upon previous research that identified four main online reading comprehension skills: locating, evaluating, synthesizing, and communicating information that are similar yet more complex than offline reading comprehension skills. In the majority of previous research, participants were in fifth grade or above. This study aimed to observe the processes younger students go through while reading online text. Participants were second grade students in a Midwestern suburban elementary school.

Qualitative methods were used to collect data while students participated in …

Unstacking The Matryoshka Nesting Doll: A Self-Study Of Playful Language Instruction For Adult Second Language Learners, Marine Pepanyan

Dissertations and Theses @ UNI

In the recent three decades teaching second language (L2) vocabulary has expanded from sentence-level morphosyntactic features and pragmatics to the promotion and advancement of Communicative Language Teaching (CLT). Nevertheless, the L2 instructors are constantly seeking alternative strategies for vocabulary teaching and assessment due to a superficial level of vocabulary memorization and lack of student engagement. As an instructor-practitioner, I undertook a self-study of the process of implementing Playful Language Instruction (PLI) of L2 vocabulary in an Intensive English Program. In this self-study I combined conceptual lenses of theories of play, CLT, and the Adult Learning Theory to examine how playful …

Use Of Technology And Its Impact On Higher Order Thinking In The Science Classroom, Mauree Angelina Haage

Dissertations and Theses @ UNI

This study focuses on examining the impact of technology on higher order thinking in the science classroom by first examining the impact of a teacher’s knowledge of Bloom’s Revised Taxonomy on the integration of higher order thinking activities and then by examining what levels of higher order thinking exist when technology was utilized. Previous research has found correlations between the levels of Bloom’s Taxonomy exhibited when using technology, particularly probeware, simulations/virtual labs, and special software like LoggerPro. In addition, previous research has shown a trend of teachers inaccurately categorizing their lessons and activities as having a higher order thinking level …

The Impacts Of Adolescents' Leisure Activity Types On Psychological Well-Being, Academic Self-Efficacy, Self Esteem, And Stress, Dongyub Back

Dissertations and Theses @ UNI

Korean teenager deviance, school violence, and school dropout caused by academic stress are serious social issues within the country. High levels of student stress are likely to bring about depression and suicide resulting in a significant effect on their psychological well-being and life satisfaction. It is of particular concern for middle school students experiencing rapid physical and psychological developmental changes without proper support. Forty-five percent of Korean students’ indicated stress in their life and 27% experienced depression (Statistics Korea, 2019). Also, Korean middle school students (27.3%) have suicide impulse (Youm & Kim, 2019). These youth development issues are considered social …

Quantifying Genomic Diversity And Growth In Iowa Bluegill, Jeremy Raymond Abels

Dissertations and Theses @ UNI

Bluegill (Lepomis macrochirus) is one of the most fished species in Iowa. However, after an initial stocking event, lakes rarely receive additional stockings owing to a high rate of natural reproduction. For this reason, the genetic diversity of Bluegill populations remains understudied in the context of fisheries and natural resource management. Additionally, the extent to which genetics influences the growth rate of Bluegill on a population level has not yet been extensively examined. The goal of this study was to understand the diversity of Iowa’s Bluegill population and to determine if there is a genetic association with growth …

Graduate Recital: Colin Evers, Piano, Colin Evers

Dissertations and Theses @ UNI

On April 14th, 2022, pianist Colin Evers performed a solo piano recital in Davis Hall of the Gallagher-Bluedorn Performing Arts Center, at the University of Northern Iowa in Cedar Falls, Iowa. The recital consisted of Piano Sonata No. 8 in C minor Op. 13 “Pathétique” by Ludwig van Beethoven, Sonatine pour Piano by Maurice Ravel, Liebesleid by Fritz Kreisler, arranged for solo piano by Sergei Rachmaninoff, Étude No. 12 in D-sharp minor, Op. 8, by Alexander Scriabin, and Ballade No. 4 in F minor Op. 52 by Frédéric Chopin.

Association Between Habitat And The Genetic Diversity Of The Brown-Belted Bumblebee (Bombus Griseocollis) In The Agricultural Landscape Across Northeast Iowa, Clarissa Elizabeth Bruns

Dissertations and Theses @ UNI

Wild bumblebees (Hymenoptera: Apidae) are key pollinators in natural ecosystems and major contributors to pollination in agriculture. Despite this, numerous bee species are in decline from introduced pathogens, pesticides, and habitat fragmentation. In the Midwestern United States, the land is dominated by agricultural landscape, and farming practices result in limited floral resources and frequently disturbed nesting grounds for bee species. In this thesis, I examine the genetic diversity between and within populations of brown-belted bumblebee (Bombus griseocollis) across northeast Iowa and test for population genetic structure between reconstructed prairies within 3 years of establishment and prairies >10 years …

Not Our Problem: Ingroup Glorification Facilitates Moral Disengagement And Exclusion, Matthew Gunderson

Dissertations and Theses @ UNI

The present study examined how ingroup/outgroup identification and harm predict cognitive restructuring and the shifting of blame. Drawing on Moral Disengagement Theory (Bandura, 1999), which holds that individuals create a new version of reality that allows them to violate their moral beliefs, I hypothesized that implicating the ingroup, lower levels of perceived harm, and higher ingroup glorification would result in more moral disengagement. Integrating Moral Disengagement Theory with Moral Exclusion Theory (Opotow, 1990), I further hypothesized that moral exclusion—the removal of others from the moral community—would also be greater. 422 participants recruited over Prolific read a modified news article about …

Students Vs. Suspects: A Qualitative Examination Of Stereotype Threat And The Impact On Behavior Of Black Males, Ryan J. Williamson

Dissertations and Theses @ UNI

This qualitative study focused on the impact of stereotype threat on the behavior of black males in the educational system. Black males currently involved in the juvenile justice system were interviewed about their lived experiences in the educational system. The literature surrounding stereotype threat focuses on academic achievement and performance. It provides spaces in the potential of stereotype threat impacting behavior.

Stereotype threat argues that individuals will confirm a self-characteristic which supports a negative stereotype associated with a specific group within society (Spencer et al., 2016). In theory, people will underperform based on a preconceived notion of failure. If a …

The New Independents: A Historical Analysis Of Webcomics And Webtoon, Leonal A. Sepúlveda S.

Dissertations and Theses @ UNI

Webcomics have now existed as a form of graphic literature for slightly over thirty years, evolving along with computer technology and in turn reflecting the changes in culture, style and preferences for both independent artists on the Internet and their audiences. The evolution of the webcomic illustrates how the changing trends in technology and profit interests shape stylistic and narrative sensibilities. In turn, the offshoot medium of webtoons, whose history parallels the webcomic directly, illustrates the way the presentday independent webcomic sphere is shaped by the demands of contents platforms that demand its creatives constantly produce content to maintain active …

A Study Of Johann Sebastian Bach’S Toccata In E Minor, Bwv 914; Ludwig Van Beethoven’S Piano Sonata Op. 10, No. 3 In D Major; Claude Debussy’S Pour Le Piano L. 95; And Frederic Chopin’S Ballade No. 1 In G Minor, Op. 23, Hanna Stolper

Dissertations and Theses @ UNI

This paper discusses a work of four different composers, two from the 1700s and two from the 1800s. Each piece has a brief summary of the historical context of the piece and analyzes each movement of the pieces.

Media Framing Of Marriage Practices In Afghanistan, Hakima Afzaly

Dissertations and Theses @ UNI

Culturally, in Afghanistan, marriage is given much importance and seen as something that completes life. Through this study, I analyze how marriage practices, such as dowry (Mahr), bride price, and the “virginity ritual,” are described in newspapers and magazines of Afghanistan. In particular, I explore how the popular press, such as 8 Sobh and Khama Press in Afghanistan frame their discussion of marriage practices. The findings from this analysis reveal that newspapers and magazines of Afghanistan frame marriage as an economic issue and a major focus of the articles is on the financial pressure on poor families due to the …

"Land Of The Silver Birch": Environmental Attitudes And Place-Making In A Northern Minnesota Boy Scout Camp, 1960-1975, John Mark Fretham

Dissertations and Theses @ UNI

In 1959, leaders of the Minnesota Valley Council, BSA (headquartered in Mankato, MN) began making plans to create a new Boy Scout camp to replace their recently built camp in Southern Minnesota. The previous fifteen years of the post-World War II era had produced significant shifts in ideas about wilderness, what constituted quality outdoor recreation, growing anxiety about masculinity in the Cold War era, and expansion of the promotion and adoption of a North Woods tourist culture. These changes helped lead the council to begin looking for a site to create a new Boy Scout camp and build Camp Cuyuna …

3d-Printed Gelatin-Alginate Hydrogel Dressings For Burn Wound Healing: A Comprehensive Study, Fateme Fayyazbakhsh, Michael J. Khayat, Ming-Chuan Leu

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Burn Wound Treatment is Still a Clinical Challenge Due to the Severity of Tissue Damage and Dehydration. among Various Wound Dressings, Hydrogel Materials Have Gained Significant Attention for Burn Wound Treatment in Clinical Practice Due to their Soothing and Moisturizing Activity. in This Study, 3D-Printed Dressings Were Fabricated using Clinically Relevant Hydrogels for Deep Partial-Thickness Burn (PTB) Wounds. Different Ratios of Gelatin and Alginate Mixture Were 3D-Printed and Examined in Terms of Rheological Behavior, Shear Thinning Behavior, Mechanical Properties, Degradation Rate, and Hydration Activity to Tune the Hydrogel Composition for Best Functionality. the Cell-Laden Dressings Were Bioprinted to Evaluate the …

Improving Age Of Information With Interference Problem In Long-Range Wide Area Networks, Preti Kumari, Hari Prabhat Gupta, Tanima Dutta, Sajal K. Das

Computer Science Faculty Research & Creative Works

Low Power Wide Area Networks (LPWAN) offer a promising wireless communications technology for Internet of Things (IoT) applications. Among various existing LPWAN technologies, Long-Range WAN (LoRaWAN) consumes minimal power and provides virtual channels for communication through spreading factors. However, LoRaWAN suffers from the interference problem among nodes connected to a gateway that uses the same spreading factor. Such interference increases data communication time, thus reducing data freshness and suitability of LoRaWAN for delay-sensitive applications. To minimize the interference problem, an optimal allocation of the spreading factor is requisite for determining the time duration of data transmission. This paper proposes a …

Orodispersible Hyaluronic Acid Film Delivery For Oral Wound Healing In Rats, Ok Hyung Nam, Jeong Hyun Lee, Ko Eun Lee, Yong Kwon Chae, Myoung-Han Lee, Dong-Keon Kweon, Mi Sun Kim, Hyo-Seol Lee, Sung Chul Choi

Journal of Dental Sciences

Abstract Background/purpose Oral wound healing undergoes a dynamic process of oral environment. This study aimed to investigate the effects of hyaluronic acid (HA) film on oral wound healing in a rat model. Materials and methods A total of 60 rats with tongue wounds (5 mm in diameter) were randomly divided into control ( n = 20), HA gel ( n = 20), and HA film groups ( n = 20). The animals were sacrificed on either 3 or 7 days after the experiment. Clinical, histological, and quantitative reverse transcriptase-polymerase chain reaction analysis were performed to evaluate the healing rate, inflammation, …

Involvement Of Endoplasmic Reticulum Stress And Cell Death By Synthesized Pa-Pdt In Oral Squamous Cell Carcinoma Cells, Hyo-Eun Yoon, Mee-Young Ahn, Yong-Chul Kim, Jung-Hoon Yoon

Journal of Dental Sciences

Abstract Background/purpose Photodynamic therapy (PDT) is a therapeutic alternative for malignant tumors that uses a photosensitizer. This study examined whether synthesized Pheophorbide a (Pa) -PDT induced apoptosis and autophagy involving endoplasmic reticulum (ER) stress in oral squamous cell carcinoma (OSCC) cells. Materials and methods Human OSCC cells were treated with Pa-PDT, and cell proliferation was examined by MTT assay. Apoptosis and autophagy were measured using Western blot analysis. ER stress was examined using RT-PCR and Western blot analysis. In vivo murine OSCC animal model were treated with intratumoral (IT) Pa-PDT, and investigated the therapeutic effect. Results Pa-PDT significantly inhibited the …

Evaluation Of Virtual Screening Strategies For The Identification Of Γ-Secretase Inhibitors And Modulators, Alicia Ioppolo, Melissa Eccles, David Groth, Giuseppe Verdile, Mark Agostino

Research outputs 2022 to 2026

γ-Secretase is an intramembrane aspartyl protease that is important in regulating normal cell physiology via cleavage of over 100 transmembrane proteins, including Amyloid Precursor Protein (APP) and Notch family receptors. However, aberrant proteolysis of substrates has implications in the progression of disease pathologies, including Alzheimer’s disease (AD), cancers, and skin disorders. While several γ-secretase inhibitors have been identified, there has been toxicity observed in clinical trials associated with non-selective enzyme inhibition. To address this, γ-secretase modulators have been identified and pursued as more selective agents. Recent structural evidence has provided an insight into how γ-secretase inhibitors and modulators are recognized …

The Safety And Efficacy Of Using Moxibustion And Or Acupuncture For Cancer-Related Insomnia: A Systematic Review And Meta-Analysis Of Randomised Controlled Trials, Carol Chunfeng Wang, Ellen Yichun Han, Mark Jenkins, Xuepei Hong, Shuqin Pang, Lisa Whitehead, Deborah L. Kirk, Anne Williams

Research outputs 2022 to 2026

Introduction:

This study aimed to synthesise the best available evidence on the safety and efficacy of using moxibustion and/or acupuncture to manage cancer-related insomnia (CRI).

Methods:

The PRISMA framework guided the review. Nine databases were searched from its inception to July 2020, published in English or Chinese. Randomised clinical trials (RCTs) of moxibustion and or acupuncture for the treatment of CRI were selected for inclusion. Methodological quality was assessed using the method suggested by the Cochrane collaboration. The Cochrane Review Manager was used to conduct a meta-analysis.

Results:

Fourteen RCTs met the eligibility criteria. Twelve RCTs used the Pittsburgh Sleep …

Realistic Motion Avatars Are The Future For Social Interaction In Virtual Reality, Shane L. Rogers, Rebecca Broadbent, Jemma Brown, Allan Fraser, Craig P. Speelman

Research outputs 2022 to 2026

This study evaluated participant self-reported appraisal of social interactions with another person in virtual reality (VR) where their conversational partner was represented by a realistic motion avatar. We use the term realistic motion avatar because: 1. The avatar was modelled to look like the conversational partner it represented, and 2. Full face and body motion capture was utilised so that the avatar mimicked the facial and body language of the conversational partner in real-time. We compared social interaction in VR with face-to-face interaction across two communicative contexts: 1. Getting acquainted conversation, and 2. A structured interview where the participant engaged …

Summary Of Aboriginal And Torres Strait Islander Health Status - Selected Topics 2021, Australian Indigenous Healthinfonet

Research outputs 2022 to 2026

...The HealthInfoNet has prepared this Summary as part of our contribution to support those who work in the Aboriginal and Torres Strait Islander health sector. Key health topics are summarised in plain language and an infographic style to enable readers to absorb data easily and quickly...

Strength Training In Swimming, Klaus Wirth, Michael Keiner, Stefan Fuhrmann, Alfred Nimmerichter, Gregory G. Haff

Research outputs 2022 to 2026

This narrative review deals with the topic of strength training in swimming, which has been a controversial issue for decades. It is not only about the importance for the performance at start, turn and swim speed, but also about the question of how to design a strength training program. Different approaches are discussed in the literature, with two aspects in the foreground. On the one hand is the discussion about the optimal intensity in strength training and, on the other hand, is the question of how specific strength training should be designed. In addition to a summary of the current …

Do Bird Communities Differ With Post-Fire Age In Banksia Woodlands Of South-Western Australia?, Robert A. Davis, Leonie E. Valentine, Michael D. Craig

Research outputs 2022 to 2026

Prescribed fire is a widespread management practice in fire-prone ecosystems that can have significant effects on fauna. To inform the development of appropriate prescribed burning regimes, we explored bird responses to time since fire in threatened Banksia woodlands in south-western Australia. We used area searches to estimate bird densities on 20 plots ranging from 1 to 26 years post fire. Fire had no significant effect on the overall bird community or any foraging guilds and there was no clear post-fire succession. Of the 26 frequently occurring species analysed, only two showed responses to fire, with yellow-rumped thornbills more abundant in …

Advancing Feminist Innovation In Sport Studies: A Transdisciplinary Dialogue On Gender, Health And Wellbeing, Holly Thorpe, Sheree Bekker, Simone Fullagar, Nonhlanhla Mkumbuzi, Sophia Nimphius, Madeleine Pape, Stacy T. Sims, A. Travers

Research outputs 2022 to 2026

Athlete health and wellbeing requires a holistic, multidimensional approach to understanding, supporting, and treating individual athletes. Building more supportive, inclusive, and equitable environments for the health and wellbeing of women and gender expansive people further requires gender-responsive approaches that promote broader cultural change. Feminist sport and exercise medicine practitioners, sports scientists, and social science researchers are increasingly coming together in their efforts to do this work. However, working across disciplines inevitably includes an array of ontological, epistemological, and political challenges. In this paper, we offer a curated ‘dialogue’ with a group of feminist scholars engaged in research and practice across …

Association Between Energy Balance-Related Factors And Clinical Outcomes In Patients With Ovarian Cancer: A Systematic Review And Meta-Analysis, Stephanie Stelten, Christelle Schofield, Yvonne A. W. Hartman, Pedro Lopez, Gemma G. Kenter, Robert U. Newton, Daniel A. Galvão, Meeke Hoedjes, Dennis R. Taaffe, Luc R. C. W. Van Lonkhuijzen, Carolyn Mcintyre, Laurien M. Buffart

Research outputs 2022 to 2026

Background:

This systematic review and meta-analysis synthesized evidence in patients with ovarian cancer at diagnosis and/or during first-line treatment on; (i) the association of body weight, body composition, diet, exercise, sedentary behavior, or physical fitness with clinical outcomes; and (ii) the effect of exercise and/or dietary interventions.

Methods:

Risk of bias assessments and best-evidence syntheses were completed. Meta-analyses were performed when ≥ 3 papers presented point estimates and variability measures of associations or effects.

Results:

Body mass index (BMI) at diagnosis was not significantly associated with survival. Although the following trends were not supported by the best-evidence syntheses, the meta-analyses …

Editorial: Fire Regimes In Desert Ecosystems: Drivers, Impacts And Changes, Eddie J. B. Van Etten, Matthew L. Brooks, Aaron C. Greenville, Glenda M. Wardle

Research outputs 2022 to 2026

Although not commonly associated with fire, many desert ecosystems across the globe do occasionally burn, and there is evidence that fire incidences are increasing, leading to altered fire regimes in this biome. The increased prevalence of megafires (wildfires > 10,000 ha in size and typically damaging) in most global biomes is linked to climate change, although those occurring in deserts have received far less attention, from both a research and policy perspective, than that of forested ecosystems (Linley et al., 2022). Understanding the drivers of desert fires, from climate to landscape patterns of hydrology and soil, and how these may be …

Critical Review Of The Use Of The Rorschach In European Courts, Igor Areh, Fanny Verkampt, Alfred Allan

Research outputs 2014 to 2021

In relation to the admissibility of evidence obtained using projective personality tests arose in F v. Bevándorlási és Állampolgársági Hivatam (2018). The Court of Justice of the European Union has held that an expert’s report can only be accepted if it is based on the international scientific community’s standards, but has refrained from stipulating what these standards are. It appears timely for European psychologists to decide what standards should be applied to determine whether or not a test is appropriate for psycholegal use. We propose standards and then apply them to the Rorschach because it was used in this case …

Voicing Derbarl Yerrigan As A Feminist Anti-Colonial Methodology, Vanessa Wintoneak, Mindy Blaise

Research outputs 2014 to 2021

The paper voices Derbarl Yerrigan, a significant river in Western Australia, through three imperfect, non-innocent, and necessary river-child stories. These stories highlight the emergence of a feminist anti-colonial methodology that is attentive to settler response-abilities to Derbarl Yerrigan through situated, relational, active, and generative research methods. Voicing Derbarl Yerrigan influences the methodological practices used as part of an ongoing river-child walking inquiry that is concerned with generating climate change pedagogies in response to the global climate crises and calls for new ways of thinking and producing knowledge. In particular, the authors found that voicing as a methodology includes listening and …