Nutrition And Hookworm Infection: A Causal Analysis Of The Literature, Mengting Su

Public Health Theses

Hookworm infection is one of the neglected tropical diseases, particularly in low and middle-income countries, but we know relatively little about causal evidence related to malnutrition. This is mainly due to the relatively small research community compared to those investigating the impact of hookworm infection on host nutritional status and disease complications. Causal inference is critical in epidemiology and biomedical research because it can be a powerful tool in enlightening prevention efforts and developing etiology models. The application of causal criteria to address complex epidemiological research questions is indeed helpful in proposing more interventions to improve the health and well-being …

Operationalizing The Unesco Universal Declaration On Bioethics And Human Rights Through A Trans-Cultural Lens: A Qualitative Study With Students In South Korea And The United States, Francis Yang

Public Health Theses

The UNESCO Universal Declaration on Bioethics and Human Rights (UDBHR) was a well-intentioned but controversial document. Some scholars appreciated UNESCO’s attempts at providing an internationally recognized set of ethical guidelines. Other critics maintained the UDBHR, in particular Article 12, was yet another representation of Western ideological hegemony and an ill-informed attempt at embracing universality at the expense of diversity. This paper acknowledged this debate but approaches the UDBHR in trans-cultural manner, framing the UDBHR not as an imposing guideline, but as a seed around which dialogue can coalesce. Such dialogue might engage similarities, differences, and nuances between different ethical perspectives, …

Quantitative Real-Time Pcr Assays For The Detection Of Leptospira, Alice Zhao

Public Health Theses

Leptospirosis is an infectious zoonotic disease caused by bacteria of the genus Leptospira. The genus is comprised of 40 pathogenic species divided among P1 (19) and P2 (21). Leptospirosis incurs a disproportionately large burden of disease in urban slum regions of developing countries that lack adequate sewage disposal, water treatment, and sanitation infrastructure. While P1 species have been identified in cases of human infection, it is unclear if all Leptospira species are capable of infecting humans, especially P2 species. Among P1 species, L. interrogans has been described as the most frequent specie to cause disease in both animals and humans, …

Per- And Polyfluoroalkyl Substances (Pfass) In Household Dust From North China: Occurrence, Contribution, And Human Exposure, Yakun Zhou

Public Health Theses

Measurements and analysis of an emerging contaminant of poly- and perfluoroalkyl substances (PFAS) and adverse health effects associated with PFAS have received increasing attention around the world. In this study, 64 participants’ household dust were collected in Jinan, China during September 2018 and January 2019, conducted as part of the Biomarkers of Air Pollutants Exposure in the Chinese aged 60-69 (China BAPE) study. Concentrations and composition profiles of 7 individual PFASs were determined and estimated daily intakes of PFASs via dust ingestion for children and adults were calculated. By using a dimension reduction method − principal component analysis (PCA) and …

Analysis Of Sex-Specific Prostanoid Production Using A Mouse Model Of Selective Cyclooxygenase-2 Inhibition, Rita K. Upmacis, Wendy L. Becker, Donna M. Rattendi, Raven S. Bell, Kelsey D. Jordan, Shayan Saniei, Elena Mejia

Faculty Papers and Publications

Background: Prostanoids are a family of lipid mediators formed from arachidonic acid by cyclooxygenase enzymes and serve as biomarkers of vascular function. Prostanoid production may be different in males and females indicating that different therapeutic approaches may be required during disease.

Objecti ves: We examined sex-dependent differences in COX-related metabolites in genetically modified mice that produce a cyclooxygenase- 2 (COX2) enzyme containing a tyrosine 385 to phenylalanine (Y385F) mutation. This mutation renders the COX2 enzyme unable to form a key intermediate radical required for complete arachidonic acid metabolism and provides a model of selective COX2 inhibition.

Design and …

Digital Educational Modules Development For The Career And Technical Cybersecurity Pathways During The Covid-19 Pandemic, Vukica Jovanović, Murat Kuzlu, Otilia Popescu, Petros Katsioloudis, Linda Vahala, Michael Wu, Deborah Marshall, Michael Crespo, Mary Addison

Engineering Technology Faculty Publications

Virtual learning has been used now for several decades, but it has never had a bigger impact on student learning than in the era of the COVID-19 pandemic. Universities and schools faced shutdowns all around the world, and teachers had to adapt rapidly to online mode of instruction. Many educators were faced with a triage approach with no previous experience in distance learning, a lack of resources for professional development, and already existing shortages of current educational modules that could assist them in their day-to-day jobs. This gap was especially evident in areas such as career and technical education (CTE) …

Volume 34 - The Future Of The Planet Earth: Multilateral Conversation—From Africa To The World, The Ecumencial Association Of Nigerian Theologians

Bulletin of Ecumenical Theology

Volume 34 of The Bulletin of Ecumenical Theology is available for purchase by contacting Dr. Peter Osuji at Duquesne University. After two years, issues are made freely available through the Duquesne Scholarship Collection.

Editorial (p.5)

Ecological Issues and Protection in the Democratic Republic of Congo, Roger Vanzila Munsi (p.6)

The Role of Christian Church in Earth-Care Today: Contributions of the Ghana Catholic Bishops’ Conference, 1965 to 2022, Emmanuel Abbey-Quaye (p.42)

Recent Hindu and Buddhist Approaches to Climate Change: In Dialogue with Pope Francis, Daniel Scheid (p.68)

Towards Ecological Places in the Democratic Republic Of Congo, Richard M. Tambwe (p.85)

Befriending …

Self-Reclamation Through Death: Attaining Creoleness In Jamaica Kincaid’S The Autobiography Of My Mother And In Praise Of Creoleness By Jean Bernabé, Patrick Chamoiseau And Raphaël Confiant, Phillip J. Jordan

Dissertations and Theses

This thesis makes the claim that Xuela, the protagonist of the novel The Autobiography of My Mother mirrors the principles of the essay In Praise of Creoleness by Jean Bernabé, Patrick Chamoiseau, and Raphael Confiant. These works, published nearly a decade apart address a process of identity formation in which specifically Caribbean identity features blend together in a fluid and complex way, the process of creolization. The essay, In Praise of Creoleness, can be seen as the manifesto of creolization, while Kincaid’s Xuela in The Autobiography of My Mother is the manifestation. Kincaid’s work presents an account of an individual’s …

Cherokee Abstract Artist Leon Polk Smith: A Convergence Of Traditions, Danielle Montanino

Dissertations and Theses

This paper analyzes how Leon Polk Smith's Indigenous roots and upbringing in Indian Country had a significant impact on his artistic practice in a time of discrimination and segregation in the United States. Through examination contextualizing his work within the history and political events of the Cherokee, Chickasaw, and Choctaw Nations it is revealed how Polk Smith developed a formal language that could navigate both worlds and be viewed through a pure abstraction lens or a lens embodying his Indigenous traditions. In addition to his Indigenous philosophies, Mesoamerican Inca Nation’s cultural motifs further ground Polk Smith’s Indigenous aesthetic, and avant-garde …

World Of Water: Betsy Damon’S Ties To Ecofeminism, Colleen Sullivan

Dissertations and Theses

This thesis establishes a critical examination of the evolution of Betsy Damon’s artistic practice as overtime she engages with ecofeminist thought. As a whole, this work extends contemporary scholarship on ecofeminist engaged art to include Damon’s artistic production while amplifying social and critical ecofeminism as necessary ideologies to explore when analyzing art through an ecofeminist lens. Beginning with her first environmentally focused work in the United States the organization of the following chapters reveals Damon’s deepened understanding and exploration of ecofeminist principles and their application to her artistic practice. It goes on to further explore Damon’s pursuit of environmentally sustainable …

Poly(Β-Gal-Thr): A New Scalable Synthetic Mucin, Manuel A. Lema

Dissertations and Theses

A method for the preparation of glycosylated polypeptides via the nucleophilic ring-opening polymerization of a glycosylated N-carboxyanhydride (NCA) monomer is reported. The synthesis of 2,3,4,6-tetraacetyl-β-galactose-threonine N-carboxyanhydride (β-AcO-Gal-Thr-NCA) monomer in 5 steps with an 8 % overall yield is described, and the single-crystal X-ray structure is provided. The effect of a series of Ni⁰-based organometallic initiators, nucleophilic amine initiators, co-catalysts, and solvents on the polymerization were explored. The kinetics of the three most promising conditions were studied in greater detail. The conditions that provided the highest yield, low polydispersity (Ð), and …

Looking At The Donor Character Through A Formalist Lens, Elena Rodriguez

Dissertations and Theses

No abstract provided.

China’S Foreign Aid Loans To Africa; Acts Of Extraction Or Development?, Francisca F. Ihekaire

Dissertations and Theses

The continent of Africa is considered a developing region due to the high rate of poverty and lack of infrastructure, and China has stepped up to offer loans to countries in need across the continent. The billions of dollars in loans that China has widely distributed among African countries raises serious concerns. Angola and Zambia are two countries in Africa considered as developing nations. The two countries, in dire need of infrastructure, have desperately sought loans from the Chinese government. Chinese loans have become common among nations even though respected international financial institutions warn against the hidden conditionalities that are …

The Nexus Of Climate Change, Biodiversity, And Food Security: A Brazil Case Study, Andrew M. Berger

Dissertations and Theses

What is referred to as climate change today is the rapid warming of the climate, largely from human actions, and the effects that come with that warming. One study published by the United States Department of Agriculture (USDA) in 2021 argues that, “human-induced emissions of greenhouse gases have caused increases in global average temperatures, changes in precipitation timing and intensity, rising sea levels, and many other changes.” A Food and Agriculture Organization (FAO) study found that when looking at the number of countries exposed to climate extremes in five year periods from 2000 to 2020, the number of countries “exposed …

The Real And The Digital: Female Agency And Resisting The Male Gaze In Lynn Hershman Leeson’S Works, Kelly Chou

Dissertations and Theses

This thesis focuses on three major feminist works by multimedia artist, Lynn Hershman Leeson (b. 1941), that grapple with the construction and potential of female identity. Considering the works within the context of Laura Mulvey’s seminal text “Visual Pleasure and Narrative Cinema,” this paper will attempt to elucidate how Hershman Leeson’s works have engaged with the male gaze and its social and cultural implications on female identity in visual spheres. This research demonstrates how Hershman Leeson’s efforts to understand the limitations and boundaries for women reflect the same phenomenons observed by Mulvey within “Visual Pleasure.” Rejecting this, Hershman Leeson also …

Youth Musicians’ Executive Functioning And Its Impact On Emotional And Behavioral Health, Michael A. Tate

Dissertations and Theses

A growing body of neuroscience literature shows that music promotes brain development, as learning a music instrument involves multiple brain regions and neurocognitive systems. In partnership with a non-profit organization with a mission to strengthen New York City communities through music education programs, this study aimed to evaluate the effects of music training on children’s executive functioning (EF), as well as emotional and behavioral outcomes. We hypothesized that (i) children’s EF would develop more rapidly with exposure to the program; (ii) the intensity of practice would be associated with rate of growth of children’s EF, emotion regulation and behavior; (iii) …

Therapeutic Considerations For The Polycule: A Qualitative Exploration Of Consensual Non-Monogamy In Couples Treatment, Tema Watstein

Dissertations and Theses

Despite the growing visibility of consensual non-monogamy culturally and in the academic domain, treatment of CNM relationships has been understudied from the clinical perspective. This study utilized a sample of 11 clinicians, who discussed their experiences of treating non-monogamous couples through a semi-structured interview. Qualitative thematic analysis led to the emergence of robust themes, which were synthesized into three broader categories: 1. Therapeutic Process, 2. Issues in Treatment, and 3. The Meaning of Non-Monogamy. Therapists discussed their own clinical processes, with emphasis on countertransference, frame, self-disclosure, and considerations for training. Themes also emerged surrounding common issues in treatment, ranging from …

Early Risk Factors For School-Age Adhd And Irritability: The Roles Of Prenatal Risk, Intrusive Parenting Style During Preschool And Caregiver-Child Attachment Quality., Ashley M. Rainford

Dissertations and Theses

ADHD is a highly impairing neurodevelopmental disorder and the family context provides a critical early environment where children’s risk for the disorder may be heightened or reduced. A parent’s style, that is their approach to interacting and guiding the child may provide children with warmth and security, or elicit fear, distrust and disappointment, both of which in turn impact behavior. However, the parent-child relationship is not unidirectional; it is dynamic. Children with high ADHD-like behaviors have greater difficulty relating to and interacting with their caregivers, while caregivers become increasingly stressed and show greater hostility and less warmth in their parenting. …

Being Black & Blue: Sex As A Moderator Between Adverse Childhood Experiences And Depressive Symptoms Among Black Emerging Adults, Wynta C. Alexander

Dissertations and Theses

Adverse Childhood Experiences (ACEs) have been linked to adult mental health consequences (e.g., depressive symptoms). Black people are disproportionately affected by ACEs, and factors related to ethnic subgroups and/or sex may produce differential depressive outcomes. The current study examined the moderating role of sex in the association between adverse childhood experiences and depression symptoms using a life course of health approach among a sample of Black emerging adults. Participants (n = 159) of the current study were Black (e.g., African – American) and Black Caribbean (e.g., Jamaican) undergraduate students (18 – 59 years old; 72.3% female) attending a large, public …

21st Century Postmodernism: Time, Capitalism, Multiculturalism And Storytelling In Three Contemporary Novels, Raymond Joseph Calamito

Dissertations and Theses

No abstract provided.

Neural Processing Of Semantic Content In Movies, Maximilian Nentwich

Dissertations and Theses

Naturalistic stimuli, such as movies, contain interacting, multimodal and semantic features and allow for free exploration through eye movements. The full extent of neural responses to features such as motion, film cuts and eye movement behavior has not been established. The main hypothesis of this thesis is that complex multimodal and semantic stimuli in naturalistic movies engage a widespread ensemble of locations across the entire brain. To address this question I analyzed simultaneous intracranial and eyetracking data from over 6,000 electrodes across 23 patients with intractable epilepsy. Responses to fast eye movements – saccades – and film cuts are widespread …

Novel Mechanisms Of Dc And Kilohertz Electrical Stimulation, Zeinab Esmaeilpour

Dissertations and Theses

Transcranial electrical stimulation is a promising technique where a weak electrical current is applied to the scalp with the goal of modulating brain activity. Understanding the cellular mechanism of direct current (DC) and kilohertz (kHz) electrical stimulation is of broad interest in neuromodulation. More specifically, there is a large mismatch between enthusiasm for clinical applications of the method and understanding of DC and kHz novel mechanisms of action. This dissertation is centered around two main fundamental aims: 1) systematic study of the acute and long-term effects of kilohertz electrical stimulation and amplitude-modulated waveform with kHz carrier frequency using a well-established …

Modulation Of Brain Tissue Transport And Endothelial Glycocalyx And Tight Junctions Of The Blood-Brain Barrier By Transcranial Direct Current Stimulation, Yifan Xia

Dissertations and Theses

Transcranial direct current stimulation (tDCS) is a non-invasive approach to treat a broad range of brain disorders and to enhance memory and cognition in healthy individuals. In addition to directly acting on neurons by modulating the membrane potential, inducing neuronal polarization and changing cortical excitability in the brain to achieve its therapeutic effects, prior studies found that tDCS can transiently enhance the permeability (P) of the blood-brain barrier (BBB), the interface between blood circulation and brain tissue. Brain extracellular space (ECS) is a narrow microenvironment which surrounds every cell in the central nervous system (CNS). ECS occupies ~20% of brain …

The Impact Of Covid-19 On Building Energy Consumption In New York City, Martha A. Olaleye

Dissertations and Theses

Since February 2020, the spread of COVID-19 affected the world economy, with the population of people contacting the virus in New York City at that time being at the highest in the United States of America. Thus, the need for remote/online learning was adopted for the safety of faculty, staffs, and students of New York Educational institution like CCNY. In the study, I focused on energy consumption as regards to COVID and POST-COVID periods in New York City (NYC), since most employees are working from home and schools are online which implies that most commercial buildings are vacant. Also due …

Osseointegration Of A Cementless Total Knee Arthroplasty In A Murine Model Of Glucocorticoid Induced Osteoporosis, Elexis C. Baral

Dissertations and Theses

Glucocorticoid-Induced Osteoporosis (GIOP) is the second largest cause of osteoporosis worldwide. Glucocorticoid-Induced osteoporosis is rapidly, driven principally by deficient osteoblast activity (i.e., decreased bone formation) rather than increased osteoclastic activity. Glucocorticoid-type steroids (GC) are used long-term typically for inflammatory diseases such as rheumatoid arthritis, lupus, multiple sclerosis, and other autoimmune disorders. Inflammatory arthritis often leads to joint replacement at relatively young ages. However, patients who are on GC treatment appear to have poorer outcomes for total joint arthroplasty compared to healthy patients. This is thought to be due to the anti-anabolic effects of GCs and impaired bone healing and osseous …

Helium-Air Mixing In Simulated Reactor Cavities Of Very High Temperature Reactors, Abdullah Abubakar

Dissertations and Theses

Abstract

Very High Temperature Reactors (VHTRs) and High Temperature Gas Reactors (HTGRs) are Generation IV gas reactors that promise to deliver high temperature process heat and efficient electricity for both industrial and commercial purposes. They have a high level of inherent passive safety making them a viable alternative to traditional water-cooled reactors. These helium gas-cooled reactors use graphite containing U-235 TRISO fuel particles in their core, as a moderator to slow down neutrons for fission chain reactions and for general core support. In the event of a primary circuit pipe break, the coolant gas escapes into the surrounding reactor cavity …

Analysis Of Eye Movements To Cartoon Faces In Videos, Kaustubh Sapru

Dissertations and Theses

Saccades are rapid eye movements that move our gaze between successive points of fixation. They are indicative of how we direct our attention and therefore play a role in memory and cognition. For static images, it is established that saccades move faster to faces compared to other objects. We hypothesize that the same is true for videos. To test this hypothesis, saccades to faces in motion pictures have been analyzed. The analysis here entails the recording of saccades to two videos followed by a statistical study of saccades going towards faces or going away from faces. What makes this study …

A Citizen-Science Approach For Urban Flood Risk Analysis Using Data Science And Machine Learning, Candace Agonafir

Dissertations and Theses

Street flooding is problematic in urban areas, where impervious surfaces, such as concrete, brick, and asphalt prevail, impeding the infiltration of water into the ground. During rain events, water ponds and rise to levels that cause considerable economic damage and physical harm. The main goal of this dissertation is to develop novel approaches toward the comprehension of urban flood risk using data science techniques on crowd-sourced data. This is accomplished by developing a series of data-driven models to identify flood factors of significance and localized areas of flood vulnerability in New York City (NYC). First, the infrastructural (catch basin clogs, …

Development Of Cellulose-Based, Semi-Interpenetrating Network Hydrogels As Tissue-Adhesive, Thermoresponsive, Injectable Implants, Jesse Martin

Dissertations and Theses

Abstract Development of Cellulose-Based, Semi-Interpenetrating Network Hydrogels as Tissue-Adhesive, Thermoresponsive, Injectable Implants

Hydrogels are three-dimensional polymer networks with high water content and tunable mechanical properties, which have been widely investigated as replacements for soft tissues, such as the intervertebral disc (IVD). Various derivatives of the plant polysaccharide, cellulose, have been explored for use as injectable hydrogel implants. Methylcellulose (MC), which exhibits thermogelation at temperatures above 32°C, and relatively hydrophilic carboxymethyl-cellulose (CMC), are versatile cellulosic polymers that have shown promise as base materials for such applications. In prior work, functionalization with methacrylate groups allowed for the formation of stable, covalently crosslinked …

Low-Intensity Ultrasonic Neuromodulation Of The Rat Hippocampus, Duc Nguyen

Dissertations and Theses

Techniques to non-invasively modulate brain activity are important for mapping human brain circuits, and also for the treatment of a host of neurological and psychiatric disorders marked by aberrant brain activity. Though a wide range of techniques for non-invasive neuromodulation have been proposed, the conventional approaches suffer from significant limitations. Most notably, focal stimulation of deep brain regions is presently only possible with invasive optogenetic and chemogenetic approaches that require craniotomies and genetic access to the brain.

Transcranial focused ultrasound stimulation (tFUS) possesses many of the characteristics desirable from a neuromodulation approach: non-invasiveness, a spatial resolution in the order of …