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Values In Early Childhood Education (Ece): A Cross-Cultural Comparative Study Of Values For Ece Expressed In Policy Documents, Jolene Pearson, Arve Gunnestad, Sissel Mørreaunet, Sobh Chahboun Jan 2022

Values In Early Childhood Education (Ece): A Cross-Cultural Comparative Study Of Values For Ece Expressed In Policy Documents, Jolene Pearson, Arve Gunnestad, Sissel Mørreaunet, Sobh Chahboun

Education Faculty Publications

Purpose

This comparative study identifies core values expressed in Early Childhood Education (ECE) official policy documents from a sample of thirteen countries.

Design/Approach/Methods

This study employs document analysis as well as content and thematic analysis. ECE values identified in the policy documents are categorized into three groups: political and society-related values, educational values, and individual and relational values.

Findings

Document analysis reveals the values that are common across countries and those that are more specific to just one or a few countries at most. This study discusses the characteristics of these values from the perspective of globalization. In doing so, …


Functionalization Of Chitosan Based Microparticles For In Vitro 3d Culture Of Human Liver Cells, William Imes Jan 2022

Functionalization Of Chitosan Based Microparticles For In Vitro 3d Culture Of Human Liver Cells, William Imes

Williams Honors College, Honors Research Projects

Previous work involving 3D culture of human liver cells with fluorinated chitosan based microparticles has shown that their incorporation provides needed structural cues that the culture of cells alone does not provide, such as increased gas transport. However, using bare microparticles to grow large 3D cellular structures is not practical as they tend to collapse before any meaningful research can be done on them. It is proposed that this is because of the lack of extracellular matrix (ECM)components within pure cell culture in vitro, which in their absence cannot adequately facilitate biochemical communication and adhesion between cells. It is …


Analysis Of Hematocrit Levels In Walleye Sander Vitreus From Similar Waterbodies, Alyssa Hauser Jan 2022

Analysis Of Hematocrit Levels In Walleye Sander Vitreus From Similar Waterbodies, Alyssa Hauser

Journal of Earth and Life Science

Walleye Sander vitreus are a popular fish among anglers and hold a prominent place in Minnesotan’s identity as their state fish. Because of this, multiple management practices are used to ensure the continued health of their populations within Minnesota waters. In this study, the process of analyzing hematocrit levels was used to determine if the analysis of hematological parameters could be a useful tool in detecting differences in population health. To evaluate this, blood samples were acquired from age-0 and age-1 fish from two similar lakes and run through a hematocrit centrifuge to separate platelets from plasma to read the …


The Effects Of Diet On Yellow Perch Morphology Throughout Lake Bemidji, Quiana L. Radaich Jan 2022

The Effects Of Diet On Yellow Perch Morphology Throughout Lake Bemidji, Quiana L. Radaich

Journal of Earth and Life Science

Morphology is very important as it looks at the arrangement of an organism’s parts to determine their functionality, development, and how they could have changed through evolution. It is also important for the identification of species as it can show how closely species are related. This study examines if the morphology of yellow perch changes throughout Lake Bemidji. Along with examining a subset of five stomachs for each group (A-F) of yellow perch collected to determine if diet was a driving force behind morphological changes. The data collected in this study suggested that morphology does change throughout Lake Bemidji and …


Brief Of Black Women Law Scholars As Amici Curiae In Support Of Respondents, Students For Fair Admissions, Inc. V. President And Fellows Of Harvard College And Univ. Of N.C., Suzette Malveaux Jan 2022

Brief Of Black Women Law Scholars As Amici Curiae In Support Of Respondents, Students For Fair Admissions, Inc. V. President And Fellows Of Harvard College And Univ. Of N.C., Suzette Malveaux

Scholarly Articles

Amici are Black women law scholars who, based on their professional and personal experiences, share a deeply rooted commitment to defending the legality of race-conscious admissions policies in educational institutions across the country. They submit this brief to present their unique and vital perspective on the history, constitutionality, and importance of race-conscious programs like those adopted by Harvard University and the University of North Carolina (“UNC”).


Model Definition For Genetic Evaluation Of Purebred And Crossbred Lambs Including Heterosis, Napoleón Vargas Jurado, David R. Notter, Joshua B. Taylor, Daniel J. Brown, Michelle R. Mousel, Ronald M. Lewis Jan 2022

Model Definition For Genetic Evaluation Of Purebred And Crossbred Lambs Including Heterosis, Napoleón Vargas Jurado, David R. Notter, Joshua B. Taylor, Daniel J. Brown, Michelle R. Mousel, Ronald M. Lewis

Department of Animal Science: Faculty Publications

Crossbreeding is a common practice among commercial sheep producers to improve animal performance. However, genetic evaluation of U.S. sheep is performed within breed type (terminal sire, semi-prolific, and western range). While incorporating crossbred records may improve assessment of purebreds, it requires accounting for heterotic and breed effects in the evaluation. The objectives of this study were to: 1) describe the development of a paternal composite (PC) line, 2) determine the effect of direct and maternal heterosis on growth traits of crossbred lambs, 3) estimate (co)variance components for direct and maternal additive, and uncorrelated maternal environmental, effects, and 4) provide an …


Interaction Of Urea With Frequency And Amount Of Distillers Grains Supplementation For Growing Steers On A High Forage Diet, Haley F. Linder, Josh E. Sebade, Zac E. Carlson, Hannah C. Wilson, Tyler J. Spore, Mary E. Drewnoski, Jim C. Macdonald Jan 2022

Interaction Of Urea With Frequency And Amount Of Distillers Grains Supplementation For Growing Steers On A High Forage Diet, Haley F. Linder, Josh E. Sebade, Zac E. Carlson, Hannah C. Wilson, Tyler J. Spore, Mary E. Drewnoski, Jim C. Macdonald

Department of Animal Science: Faculty Publications

Two studies were conducted to determine interactions of urea inclusion to a dried distillers grains plus solubles (DDGS; 29.4% crude protein, 5.48% ether extract) supplement fed at two amounts and two frequencies to steers on a high forage diet. In Exp. 1, 120 (247 kg; SD = 20) steers were fed individually for 84 d. Steers received ad libitum grass hay (6.8% crude protein) and one of eight treatments. Treatment design was a 2 × 2 × 2 factorial. Supplement was fed daily or three times per week, amount of supplement fed was 6.36 kg dry matter (DM)/week [0.37% body …


Production Cow-Calf Responses From Perennial Forage-Based And Integrated Beef-Cropping Systems, Zac E. Carlson, Levi Mcphillips, Galen E. Erickson, Mary E. Drewnoski, Jim C. Macdonald Jan 2022

Production Cow-Calf Responses From Perennial Forage-Based And Integrated Beef-Cropping Systems, Zac E. Carlson, Levi Mcphillips, Galen E. Erickson, Mary E. Drewnoski, Jim C. Macdonald

Department of Animal Science: Faculty Publications

An experiment was conducted to measure production responses of an alternative cow-calf production system integrated into a cropping system without access to perennial forage compared to a traditional cow-calf system utilizing perennial forage. Multiparous, cross-bred beef cows (n = 160; average age = 6.2 ± 2.8 yr) were utilized in a randomized complete block experimental design and unstructured treatment design. Upon initiation, cows were blocked by age and stratified by source, assigned randomly to one of two production systems, each with four replicates (n = 20 cows/replicate). Once allotted to their treatment groups, cows remained in their experimental units for …


Evaluation Of A Novel Computer Vision-Based Livestock Monitoring System To Identify And Track Specific Behaviors Of Individual Nursery Pigs Within A Group-Housed Environment, Ty B. Schmidt, Jessica M. Lancaster, Eric T. Psota, Benny E. Mote, Lindsey E. Hulbert, Aaron Holliday, Ruth Woiwode, Lance Perez Jan 2022

Evaluation Of A Novel Computer Vision-Based Livestock Monitoring System To Identify And Track Specific Behaviors Of Individual Nursery Pigs Within A Group-Housed Environment, Ty B. Schmidt, Jessica M. Lancaster, Eric T. Psota, Benny E. Mote, Lindsey E. Hulbert, Aaron Holliday, Ruth Woiwode, Lance Perez

Department of Animal Science: Faculty Publications

Animal behavior is indicative of health status and changes in behavior can indicate health issues (i.e., illness, stress, or injury). Currently, human observation (HO) is the only method for detecting behavior changes that may indicate problems in group-housed pigs. While HO is effective, limitations exist. Limitations include HO being time consuming, HO obfuscates natural behaviors, and it is not possible to maintain continuous HO. To address these limitations, a computer vision platform (NUtrack) was developed to identify (ID) and continuously monitor specific behaviors of group-housed pigs on an individual basis. The objectives of this study were to evaluate the capabilities …


Assessing Population Structure And Genetic Diversity In Us Suffolk Sheep To Define A Framework For Genomic Selection, Carrie S. Wilson, Jessica L. Petersen, Harvey D. Blackburn, Ronald M. Lewis Jan 2022

Assessing Population Structure And Genetic Diversity In Us Suffolk Sheep To Define A Framework For Genomic Selection, Carrie S. Wilson, Jessica L. Petersen, Harvey D. Blackburn, Ronald M. Lewis

Department of Animal Science: Faculty Publications

Long-term sustainability of breeds depends on having sufficient genetic diversity for adaptability to change, whether driven by climatic conditions or by priorities in breeding programs. Genetic diversity in Suffolk sheep in the United States was evaluated in four ways: 1) using genetic relationships from pedigree data [(n = 64 310 animals recorded in the US National Sheep Improvement Program (NSIP)]; 2) using molecular data (n = 304 Suffolk genotyped with the OvineHD BeadChip); 3) comparing Australian (n = 109) and Irish (n = 55) Suffolk sheep to those in the United States using molecular data; and 4) assessing genetic relationships …


Site Of Infusion Of A Commercially Available Direct-Fed Microbial On Performance And Digestibility In Lactating Holstein Cows, K. S. Thompson, A. G. Mckeith, C. R. Krehbiel Jan 2022

Site Of Infusion Of A Commercially Available Direct-Fed Microbial On Performance And Digestibility In Lactating Holstein Cows, K. S. Thompson, A. G. Mckeith, C. R. Krehbiel

Department of Animal Science: Faculty Publications

Objective: The objective of this research was to evaluate site of infusion of a commercially available direct-fed microbial (DFM) containing 109 cfu/g of Lactobacillus acidophilus and 109 cfu/g Propionibacterium freudenreichii on DMI, rumen kinetics, ruminal VFA, digestibility, milk production, milk components, and blood metabolites in lactating dairy cows.

Materials and Methods: Four Holstein cows equipped with ruminal cannulas were used in a Latin square design experiment with 4 periods. Each 37-d period consisted of 14 d of no treatment to prevent crossover contamination, 14 d of adaptation to treatments, 8 d of sampling, and 1 d for …


Exploring Accessibility Features And Plug-Ins For Digital Prototyping Tools, Urvashi Kokate, Kristen Shinohara, Garreth W. Tigwell Jan 2022

Exploring Accessibility Features And Plug-Ins For Digital Prototyping Tools, Urvashi Kokate, Kristen Shinohara, Garreth W. Tigwell

Articles

Many digital systems are found to be inaccessible and a large part of the issue is that accessibility is not considered early enough in the design process. Digital prototyping tools are a powerful resource for designers to quickly explore both low and high fidelity design mockups during initial stages of product design and development. We evaluated 10 popular prototyping tools to understand their built-in and third-party accessibility features. We found that accessible design support is largely from third-party plug-ins rather than prototyping tools' built-in features, and the availability of accessibility support varies from tool to tool. There is potential to …


The Natural Law Ethics Of Public Health Lockdowns, Eric C. Ip Jan 2022

The Natural Law Ethics Of Public Health Lockdowns, Eric C. Ip

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.


Periodic Leave: An Analysis Of Menstrual Leave As A Legal Workplace Benefit, Hilary H. Price Jan 2022

Periodic Leave: An Analysis Of Menstrual Leave As A Legal Workplace Benefit, Hilary H. Price

Oklahoma Law Review

No abstract provided.


Communique, 2022, University Of Montana--Missoula. School Of Journalism Jan 2022

Communique, 2022, University Of Montana--Missoula. School Of Journalism

Communique, 1953-2020

An annual publication of the University of Montana’s School of Journalism. This is volume 66.


The Effect Of Anti-Aging Treatment On Expression Of Aging Markers In A Mouse Model Of Huntington Disease, Mary Isabelle E. Guerra Jan 2022

The Effect Of Anti-Aging Treatment On Expression Of Aging Markers In A Mouse Model Of Huntington Disease, Mary Isabelle E. Guerra

Honors Undergraduate Theses

Huntington disease (HD) is a fatal neurodegenerative disease caused by CAG tract expansion in the huntingtin (HTT) gene, which results in production of mutant huntingtin (mtHTT) protein. Although mtHTT is expressed throughout life, onset of HD symptoms typically begins in mid-life, around 35 to 50 years of age. Characteristic HD symptoms include motor, cognitive, and psychiatric abnormalities. The emergence of symptoms in adulthood suggests that aging may play a role in HD pathogenesis. Furthermore, markers of accelerated aging can be observed in HD patients, including telomere attrition, epigenetic alterations, and mitochondrial dysfunction. Our lab has previously observed that …


Characteristics Of Covid-19 Vaccine-Hesitant Ucf College Students And Potential Avenues For Increasing Vaccination Rates, Justin A. Barthel Jan 2022

Characteristics Of Covid-19 Vaccine-Hesitant Ucf College Students And Potential Avenues For Increasing Vaccination Rates, Justin A. Barthel

Honors Undergraduate Theses

The COVID-19 pandemic has been an ongoing disaster that has devasted millions of lives. With the development of COVID-19 vaccines in late 2020, there was a potential for populations to gain artificial active immunity in order to prevent future outbreaks. However, despite successful clinical trials, millions of citizens have been hesitant to receive the COVID-19 vaccines (Khubchandani et al., 2021). Demographics of the most prominent US vaccine-hesitant populations consist of ethnic/racial minorities and Republicans groups (Khubchandani et al., 2021). Little information is known about COVID-19 vaccine hesitancy in colleges and universities. Colleges provide an elevated risk for infection through their …


Relationship Between Video Games And Recovery From Work: A Comparison Of Different Genres And Leisure Activities, Jessica A. Gass Jan 2022

Relationship Between Video Games And Recovery From Work: A Comparison Of Different Genres And Leisure Activities, Jessica A. Gass

Honors Undergraduate Theses

Work stress can have a negative impact for both individuals and organizations, warranting research on how to recover from it. This research analyzes how the relationship between video games and work recovery differs depending on the genre of the video game played. In addition, these relationships are compared against the relationships between the recovery experiences and other leisure activities. Participants were asked to provide information on how often they play video games and engage in other leisure activities. In addition, two different measures of the four components of work recovery (psychological detachment from work, relaxation, mastery experiences, and control) were …


A Systematic Review And Meta-Analysis Of The Relationship Between The Creb Protein's Neuroplastic Functions And The Implications In Neurodegenerative Diseases: A Possible Link Between Synaptic Plasticity And Neurodegenerative Diseases, Mani Sarmast Jan 2022

A Systematic Review And Meta-Analysis Of The Relationship Between The Creb Protein's Neuroplastic Functions And The Implications In Neurodegenerative Diseases: A Possible Link Between Synaptic Plasticity And Neurodegenerative Diseases, Mani Sarmast

Honors Undergraduate Theses

In this two-part study, I investigated whether the cyclic-adenosine monophosphate response element-binding (CREB) protein has the potential to be clinically modulated as a therapeutic target for the treatment of neurodegenerative diseases. Part one consisted of a systematic review that was conducted on select articles gathered through a stepwise method to explore (1) the relationship between diseased, neurodegenerative brains and levels of active, phosphorylated CREB (pCREB), (2) increased activation of CREB as a treatment for neurodegenerative symptoms, and (3) a potential therapeutic drug for neurodegenerative diseases that can target CREB signaling. The results of the systematic review showed evidence that suggested …


A Novel Drug To Induce Apoptosis In Advanced Prostate Cancer Cells, Parshva A. Sanghvi Jan 2022

A Novel Drug To Induce Apoptosis In Advanced Prostate Cancer Cells, Parshva A. Sanghvi

Honors Undergraduate Theses

Prostate cancer is one of the leading causes of death for men in America as approximately 1 in 41 men will have prostate cancer. In this research, we focus on enzalutamide-resistant prostate cancer cells as cell resistance to enzalutamide is a prevalent obstacle in treating prostate cancer. We tested a novel compound library at different doses and observed each compound's efficacy in inducing apoptosis in enzalutamide-resistant cells. Furthermore, we analyzed the mechanism by which apoptosis was induced in compounds that showed a high efficacy at lower doses. Overall, we found that Darapladib shows promising results in treating cells that have …


Fanboys, Pow, & Mount Plot: Mnemonic Devices Used In Teaching Writing, Sarah Anderson, Alexa Bills, Kaitlyn Conlin, Eve Crawford, Natalie Eggli, Jenae Grant, Lilly Hammer, Andrew Isaacson, Kassandra Jimenez, Ryan Mansfield, Brindley Rowley, Samantha Stringham, Meghan Waldenberg, Brady Wallis, Joyce Kinkead Jan 2022

Fanboys, Pow, & Mount Plot: Mnemonic Devices Used In Teaching Writing, Sarah Anderson, Alexa Bills, Kaitlyn Conlin, Eve Crawford, Natalie Eggli, Jenae Grant, Lilly Hammer, Andrew Isaacson, Kassandra Jimenez, Ryan Mansfield, Brindley Rowley, Samantha Stringham, Meghan Waldenberg, Brady Wallis, Joyce Kinkead

The Utah English Journal

Cicero ( 106-43 BCE) was renowned during his lifetime and influential long after as an extraordinary orator and writer, able to recall long speeches from memory. A technique termed the memory palace, which associates memory with locations-also called method of loci-enabled ancient rhetoricians to deliver stimulating speeches. Retention of information was essential for delivering speeches not just because it was impressive but also due to the paucity of writing materials. Writers and orators relied on wax tablets that could be inscribed with a stylus but could not archive the text; as a result, the information had to be memorized, part …


“It Doesn’T Matter How Good The School Is If You Don’T Learn To Socialize”: Latinx Immigrant Students’ Testimonios Of Coping With Social Isolation In High School, Jenn M. Lilly Jan 2022

“It Doesn’T Matter How Good The School Is If You Don’T Learn To Socialize”: Latinx Immigrant Students’ Testimonios Of Coping With Social Isolation In High School, Jenn M. Lilly

Social Service Faculty Publications

Understanding how Latinx immigrant youth cope with the stressor of social isolation is vital to understanding and improving their functioning and well-being; yet little is known about how they cope with experiences of social isolation in school. To fill this gap in the literature, the purpose of this exploratory study was to qualitatively examine the coping strategies that Latinx immigrant students utilized in the face of social isolation in one high school in a newer Latinx destination in the U.S. south. This study employed a narrative and culturally congruent methodological approach, analyzing the digital testimonios of 5 female and 2 …


“When You Come Together And Do Everything, It’Ll Be Better For Everybody”: Exploring Gender Relations Among Two Southeastern Native American Tribes, Jenn M. Lilly, Catherine E. Mckinley, Hannah Knipp, Jessica L. Liddell Jan 2022

“When You Come Together And Do Everything, It’Ll Be Better For Everybody”: Exploring Gender Relations Among Two Southeastern Native American Tribes, Jenn M. Lilly, Catherine E. Mckinley, Hannah Knipp, Jessica L. Liddell

Social Service Faculty Publications

Prior to the imposition of patriarchal colonial norms, Native American (NA) gender relations were characterized as complementary and egalitarian; however, little research has explored gender relations within NA communities today. This study used a community-based critical ethnography to explore contemporary NA gender relations with a purposive sample of 208 individuals from the “Coastal Tribe” and 228 participants from the “Inland Tribe.” After participant observation, interviews, and focus groups were conducted, a collaborative approach to reconstructive analysis was used to identify themes in the data. Within these communities, gender relations tended to reflect egalitarian and cooperative but gendered norms, and participants …


A “Totally, Acceptably Racist Environment”: Examining Anti-Black Racism In A School Of Social Work, Jenn M. Lilly, Jasmine Hillyer, Eboni Jaggers, Kayla Garnigan Jan 2022

A “Totally, Acceptably Racist Environment”: Examining Anti-Black Racism In A School Of Social Work, Jenn M. Lilly, Jasmine Hillyer, Eboni Jaggers, Kayla Garnigan

Social Service Faculty Publications

Social work education is considered an important venue for advancing the field’s commitment to anti-racism. This research employed collective auto- biographical methods within a Critical Race Theory framework to explore Black social work students’ experiences of anti-Black racism in the learning environment of a Predominantly White Institution. Data was analyzed through a collaborative, inductive approach. Analysis revealed four interrelated themes: 1) racial microaggressions directed at Black students; 2) the perceived complicity of school administration in maintaining a racist environment; 3) the harm that an anti-Black racist learning environment caused to Black students; and 4) a relational approach to challenging anti-Black …


Uri Undergraduate And Graduate Course Catalog 2022-2023, University Of Rhode Island Jan 2022

Uri Undergraduate And Graduate Course Catalog 2022-2023, University Of Rhode Island

URI Course Catalogs Archive

This is a downloadable PDF version of the University of Rhode Island course catalog.


Biochar From Empty Date Fruit Bunch As An Adsorbent To Remove Eriochrome Black T And Methylene Blue From Aqueous Solution, Houari Bella, Hayet Bendaikha Jan 2022

Biochar From Empty Date Fruit Bunch As An Adsorbent To Remove Eriochrome Black T And Methylene Blue From Aqueous Solution, Houari Bella, Hayet Bendaikha

Applied Environmental Research

Date fruit has a significant role in Sahara countries' economies. In this study, a bunch of empty dates waste was used to produce biochar, which will be used to adsorb Eriochrome black T (EBT) and methylene blue (MB) dyes from aqueous solution. The dates bunch was washed, dried, and ground into small particles. Then it was heated in a muffle furnace at 850 °C. The biochar from empty date bunches (BEDB) characteristics before and after adsorption was determined by using scanning electron microscopy (SEM) and Fourier transform infrared (FTIR) spectroscopy. The experiment has used different parameters notably initial concentration (25 …


Efficacy Of Prebiotic Dietary Intervention To Mitigate Risks For Dementia Via The Gut-Brain Axis, Lucille M. Yanckello Jan 2022

Efficacy Of Prebiotic Dietary Intervention To Mitigate Risks For Dementia Via The Gut-Brain Axis, Lucille M. Yanckello

Theses and Dissertations--Pharmacology and Nutritional Sciences

Alzheimer’s disease (AD) is the most common form of dementia with various risk factors including age, environmental factors such as brain injury and genetic factors, such as the E4 allele of the Apolipoprotein gene. Presence of the APOE4 allele increases AD risk by two- to four- fold. Recent studies have shown that mild traumatic brain injury (mTBI), even without loss of consciousness, increases risk of dementia diagnosis by more than two-fold in military personnel and is also a significant environmental risk factor for developing dementia in the general population. The gut-brain axis (GBA) or bi-directional communication between the brain and …


Dementia Care Among Somali Elders, Emmanuel Asante Opoku Jan 2022

Dementia Care Among Somali Elders, Emmanuel Asante Opoku

All Graduate Theses, Dissertations, and Other Capstone Projects

Caring for persons with dementia is demanding and complicated since there is “no one-size-fits all formula for dementia care. The care needs to be modified to fit the various stages of the condition and each family's unique situation. Racial and ethnic differences place unique demand on all the forms of dementia care; in-home care (IHC), long-term care (LTC), adult day centers(ADC), short term care (STC) and hospice care (HC).

This paper aimed to study how Somali elders think and interact with dementia care services, from in-home care to hospice care. Some recommendations to study this issue is to do a …


Decolonizing The Map: Indigenous Maps And Gis, Henry Osborne Beimers Jan 2022

Decolonizing The Map: Indigenous Maps And Gis, Henry Osborne Beimers

All Graduate Theses, Dissertations, and Other Capstone Projects

Indigenous mapping practices have yet to be widely considered by geographers outside of a historical context. In this paper I critique the geographic research paradigm through the lens of settler colonial and critical cartographic theory. I present evidence for the value of Indigenous mapping practices through a historical-critical GIS analysis of two Indigenous maps, and a creation of a story map to present those results. Finally, I suggest future routes to integrate digital mapping and Indigenous mapping practices, for pedagogy, and for preserving cultural resources, language, land, and traditional Indigenous knowledge.


Investigating Anxiety-Like Behavior As A Non-Motor Side Effect Of Deep Brain Stimulation Of The Subthalamic Nucleus In A Parkinsonian Rat Model, Carter Mulder Jan 2022

Investigating Anxiety-Like Behavior As A Non-Motor Side Effect Of Deep Brain Stimulation Of The Subthalamic Nucleus In A Parkinsonian Rat Model, Carter Mulder

All Graduate Theses, Dissertations, and Other Capstone Projects

Parkinson’s disease (PD) is estimated to impact nearly 10 million people globally and is estimated to increase in the future. PD is a progressive neurodegenerative disease that worsens through continuous cell death of dopaminergic neurons. This cell death can create motor symptoms such as bradykinesia, tremor, and muscular rigidity. Subthalamic nucleus deep brain stimulation, STN DBS, is a surgical intervention which places stimulating electrodes in the STN greatly improving motor symptoms. However, STN DBS has been reported to possibly influence non-motor symptoms such as anxiety both acutely and long-term, which decreases the quality of life for those with PD. We …