Digital Commons Network^™

The Isolation And Characterization Of Bacteriophage Hasitha, Gillian Brown

Mahurin Honors College Capstone Experience/Thesis Projects

Microbacteriophage Hasitha is a virus that infects Microbacterium foliorum, a bacterium associated with grasses that was first discovered in Germany. Hasitha was isolated from an enriched compost sample and is of particular interest due to its unusual growth pattern. Most bacteriophages require actively growing host cells to produce new phage progeny. However, Hasitha can infect and kill stationary (non-replicating) bacterial cells. We discovered this unusual characteristic through a fortuitous observation of infected lawns that were allowed to incubate in the lab workspace for approximately one month. During this time, a noticeable “halo” grew around the initial site of infection …

Entanglements Of Identity And Resilience In The Camp Fire’S Network Of Disaster-Specific Facebook Groups, Bailey C. Benedict

Management Faculty Publications

The Camp Fire in California (November 2018) was one of the most destructive wildfires in recorded history. Dozens of Facebook groups emerged to help people impacted by the Camp Fire. Its variety and prevalence throughout recovery make this network of disaster-specific, recovery-oriented social media groups a distinct context for inquiry. Reflexive thematic analysis was performed on 25 interviews with group administrators and publicly available descriptive data from 92 Facebook groups to characterize the composition of the network and explore identity in the groups. Group members’ identities fell into two categories—helpers and survivors—while the groups consisted of six identities: general, specialized, …

Jacob G. Mulder Papers, William Minnick, Douglas Firth Anderson

Finding Aids

The Jacob G. Mulder Papers document the life of Jacob (Jake) Mulder during the years of his military service in the First World War, 1918-1919. The collection includes correspondence between Jacob and his family and friends, newspaper clippings, army issued materials and papers, and a photograph. Collectively, these materials provide an insight of an enlisted Dutch-American farmer of the American Expeditionary Force (AEF) in Europe.

Ifn-Γ Attenuates Eosinophilic Inflammation But Is Not Essential For Protection Against Rsv-Enhanced Asthmatic Comorbidity In Adult Mice, Abenaya Muralidharan, Md Bashir Uddin, Christopher Bauer, Wenzhe Wu, Xiaoyong Bao, Keer Sun

Journal Articles: Pathology and Microbiology

The susceptibility to respiratory syncytial virus (RSV) infection in early life has been associated with a deficient T-helper cell type 1 (Th1) response. Conversely, healthy adults generally do not exhibit severe illness from RSV infection. In the current study, we investigated whether Th1 cytokine IFN-γ is essential for protection against RSV and RSV-associated comorbidities in adult mice. We found that, distinct from influenza virus, prior RSV infection does not induce significant IFN-γ production and susceptibility to secondary Streptococcus pneumoniae infection in adult wild-type (WT) mice. In ovalbumin (OVA)-induced asthmatic mice, RSV super-infection increases airway neutrophil recruitment and inflammatory lung damage …

Insect Cell Expression And Purification Of Recombinant Sars-Cov-2 Spike Proteins That Demonstrate Ace2 Binding, Lucas R. Struble, Audrey L. Smith, William E. Lutz, Gabrielle Grubbs, Satish Sagar, Kenneth W. Bayles, Prakash Radhakrishnan, Surender Khurana, Dalia El-Gamal, Gloria E. O. Borgstahl

Journal Articles: Pathology and Microbiology

The COVID-19 pandemic caused by SARS-CoV-2 infection has led to socio-economic shutdowns and the loss of over 5 million lives worldwide. There is a need for the identification of therapeutic targets to treat COVID-19. SARS-CoV-2 spike is a target of interest for the development of therapeutic targets. We developed a robust SARS-CoV-2 S spike expression and purification protocol from insect cells and studied four recombinant SARS-CoV-2 spike protein constructs based on the original SARS-CoV-2 sequence using a baculovirus expression system: a spike protein receptor-binding domain that includes the SD1 domain (RBD) coupled to a fluorescent tag (S-RBD-eGFP), spike ectodomain coupled …

Type I Ifn Signaling Protects Mice From Lethal Sars-Cov-2 Neuroinvasion., Md Bashir Uddin, Yuejin Liang, Shengjun Shao, Sunil Palani, Michael Mckelvey, Scott C. Weaver, Keer Sun

Journal Articles: Pathology and Microbiology

Multiple organ damage is common in patients with severe COVID-19, even though the underlying pathogenic mechanisms remain unclear. Acute viral infection typically activates type I IFN (IFN-I) signaling. The antiviral role of IFN-I is well characterized in vitro. However, our understanding of how IFN-I regulates host immune response to SARS-CoV-2 infection in vivo is incomplete. Using a human ACE2-transgenic mouse model, we show in the present study that IFN-I receptor signaling is essential for protection against the acute lethality of SARS-CoV-2 in mice. Interestingly, although IFN-I signaling limits viral replication in the lung, the primary infection site, it is dispensable …

Antebellum Redux, Allen M. Price

Harpur Palate: a Literary Journal

Allen M. Price’s essay ‘Racism: A Prelude to a Negro’s Suicide Note’ is a finalist in Witness magazine’s 2023 Literary Award Nonfiction Contest. His essay ‘My Friend Blackness’ won Blue Earth Review‘s 2022 Dog Daze Flash Creative Nonfiction Contest. His essay ‘The Jailed Down Negro’ won the 2021 Columbia Journal Winter Contest (chosen by Pamela Sneed). He’s a 2023 and two-time 2022 Pushcart Prize nominee. His work appears or is forthcoming in Post Road, North American Review, upstreet, Zone 3, Sweet, The Masters Review, Terrain.org, Shenandoah, Hobart, Transition, Vol. 1 Brooklyn, Juked, River Teeth, The Fourth River Jellyfish Review, Bayou, …

In Defense Of All My Bitches, Katrina Agbayani

Harpur Palate: a Literary Journal

Katrina Agbayani is a former editor with Acta Victoriana and La Mosaic. Her work has been published, or is forthcoming, in SAND, Capsule Stories, Kitchen Table Quarterly, the UC Review, and elsewhere.

Camas, Winter 2022

Camas

Nonfiction:

What We Found in the Woods / Keene Short -- To Thrive in a Harsh Land / Amy Zaranek -- Ghosts of Icicle Ridge / Claire Thompson

Fiction:

Mole Man / Dave Barrett -- Formicidae Carnivore / Nora Studholme

Poetry:

Why We Tell Stories / Madronna Holden -- The Green Man / Hannah Rodabaugh -- Stay Undomesticated / Abby Seethoff -- Waiting / Oisin Breen -- man makes plans / Priya Subberwal

Art & Photography:

Dylan Albans -- Guilherme Bergamini -- Natalia Boise -- Lawrence Bridges -- Jesse Caverly -- William C. Crawford -- Rashail DeMinck …

Cover And Contents

Turkish Journal of Zoology

No abstract provided.

Mechanisms Of Cannabidiol (Cbd) In Cancer Treatment: A Review, Camren G. Heider, Sasha A. Itenberg, Jiajia Rao, Hang Ma, Xian Wu

Biomedical and Pharmaceutical Sciences Faculty Publications

Cannabis sativa L. (Cannabis) and its bioactive compounds, including cannabinoids and non-cannabinoids, have been extensively studied for their biological effects in recent decades. Cannabidiol (CBD), a major non-intoxicating cannabinoid in Cannabis, has emerged as a promising intervention for cancer research. The purpose of this review is to provide insights into the relationship between CBD and cancer based on recent research findings. The anticancer effects of CBD are mainly mediated via its interaction with the endocannabinoid system, resulting in the alleviation of pain and the promotion of immune regulation. Published reviews have focused on the applications of CBD in cancer pain …

Full Issue, Fall 2022, In The Ords

In the Ords: CSUMB Literary Arts Journal

No abstract provided.

Rob Bruxvoort, Ann Lundberg

Oral Histories

Rob Bruxvoort, former assistant chief on the Orange City FIre Department, served the community for 25 years. He recounts memorable events during his career, including accidents, rescues, and fires. He also discusses training practices.

Editorial: Genetic Basis Of Tolerance Induction Defects Underlying The Development Of Autoimmune Pathologies., Jeremy Racine, Laurence Morel, Yi-Guang Chen, David V. Serreze

Faculty Research 2022

No abstract provided.

Commonalties Between The Ojibwa, Ese Eja, And Makiritare, Victoria Slight

Spectrum

No abstract provided.

Harpur Palate Volume 21, Issue 1, Harpur Palate .

Harpur Palate: a Literary Journal

Contributors: Susan Finch | Liam Callanan | Ben Dymion | Sophie Elan | Danielle LaVaque-Manty | Nelson Lloyd | Penny Pennell | Cynthia Belmont | Janine Blue | Jason M. Jones | Elisabeth Blair | Shelly Cato | Mary Christine Delea | Jillian A. Fantin | Joshua Jones | Audrey King | Tyler Kline | Violet Mitchell | Emily Pérez | Casey Lynn Roland | Keith Stahl | KT | Jeff Tigchelaar | Leslie Williams

Infestation, Susan Finch

Harpur Palate: a Literary Journal

No abstract provided.

The Final Say, Kt .

Harpur Palate: a Literary Journal

No abstract provided.

A Deeper Understanding Of The Temple In 175 Entries, David Calabro

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

In a must-have book written for a Latter-day Saint audience, Donald Parry offers profound insights into 175 features of ancient and modern temples, including architectural features, aspects of ritual, and temple-related doctrine.

One Shell Of A Problem: Cumulative Threat Analysis Of Male Sea Turtles Indicates High Anthropogenic Threat For Migratory Individuals And Gulf Of Mexico Residents, Micah Ashford

Masters Theses

Human use of oceans has dramatically increased in the 21st century, with some of the highest rates of change found within the Gulf of Mexico and Caribbean. Sea turtles are particularly vulnerable to anthropogenic stressors in the marine environment as they make lengthy migrations between foraging and breeding sites often along coastal migration corridors. Sea turtles face severe population pressure from humans, yet little is known about how movement and threats interact specifically for male sea turtles. To better understand male sea turtle movement, and the threats they encounter within their expansive ranges, we tagged 40, adult male sea turtles …

Assessment Of Repeatability And Behavioral Syndromes In Genetically Distinct Clades Of Eastern Red-Backed Salamanders (Plethodon Cinereus), Kelsey Garner

Masters Theses

Animal personality implies limited behavioral plasticity and behavioral traits which are correlated across contexts. Correlated behaviors, sometimes referred to as behavioral syndromes, have the potential to inhibit behavioral traits from evolving independently. Limits on behavioral variation can influence a population’s ability to invade new geographic areas and exploit new niches. One way to explore such variation is to examine behavioral syndromes in genetically distinct populations of wide-ranging species that exhibit different dispersal pathways and distances. The personality-dependent dispersal syndrome suggests that certain traits, such as exploratory and risk-taking behavior, are correlated with dispersal success. The Eastern Red-backed Salamander (Plethodon …

The Body As The Temple Of God, Lareina Hingson

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

Metaphors occur when there is a contradiction in the senses of the words used that cause the text to be interpreted non-literally, as Paul Ricoeur has noted. The Apostle Paul’s letter to the Corinthians describing the body as a temple has been taken to be one such scriptural metaphor: “Know ye not that ye are the temple of God, and that the Spirit of God dwelleth in you? … know ye not that your body is the temple of the Holy Ghost which is in you?” (1 Corinthians 3:16; 6:19). As a metaphor, it is a strong one. The supposed …

Should I Be My Brother’S Keeper? Yes And No, Daniel C. Peterson

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

We typically teach and often even sing that we should be our brothers’ (and sisters’) keepers. And we do it with the very best and most holy of intentions. For many of us, indeed, loving and caring for our brothers and sisters is at the very heart of what it means to live a life of truly Christian discipleship. And rightly so. But there’s another way to think about this matter. I’ve pondered it for decades, and now, maybe some others will also find it thought-provoking.

2022 Spring And Winter - Schedule Of Classes, Office Of The Registrar, East Tennessee State University

Registration Resources

No abstract provided.

Incidence And Prognosis Of Cranial Neuropathies In Children With Covid-19: A Systematic Review And Meta-Analysis, Priyanka Bisarya

Yale Medicine Thesis Digital Library

Objective:In addition to experiencing classic respiratory symptoms, pediatric COVID-19 patients have presented with neurological manifestations including cranial nerve dysfunction. The evidence regarding these presentations has yet to be synthesized, and the aim of this work was to determine how commonly cranial neuropathies are associated with pediatric COVID-19 cases and what the prognosis is for these children. Methods: A systematic review was conducted using a comprehensive search strategy of OVID Medline, OVID Embase, and Web of Science databases. The inclusion criteria were research articles that described pediatric COVID-19 patients with cranial nerve involvement. Results: The search yielded 5497 articles. Thirty-four (34/5497) …

Video Games And The Federal Trade Commission Act: An Analysis Of The Practices Of Video Game Developers And Their Effects On Players

Florida A & M University Law Review

The purpose of this Note is to propose that the FTC exercise its broad authority under § 45 of the Federal Trade Commission Act (“FTC Act”) to address the seemingly innocuous conduct of the video game industry. To that end, this Note is divided into two sections. The first section reviews administrative and judicial opinions interpreting the history and scope of the FTC. It also notes how the Wheeler-Lea Amendment expanded the Commission’s power to include consumer protection. The second section identifies specific acts and practices used by video game developers (hereinafter “VGDs”) to demonstrate how they fall within the …

2022-2023 - Quillen College Of Medicine Operating Budget (October), Budget And Financial Planning, East Tennessee State University

College of Medicine Operating Budgets and Analysis

No abstract provided.

2022-2023 - Quillen College Of Medicine Operating Budget (July), Budget And Financial Planning, East Tennessee State University

College of Medicine Operating Budgets and Analysis

No abstract provided.

2022-2023 - Etsu General Academic Operating Budget (October), Budget And Financial Planning, East Tennessee State University

ETSU General Academic Operating Budgets and Analysis

No abstract provided.

School Readiness (Behavior), Kathy R. Doody Ph.D.

Sample module-themed coursework with Sesame Street examples

This module will provide an overview of the social-emotional and adaptive skills required for kindergarten success. The module will also provide insight into how Sesame Street has prepared children for their first days of preschool or kindergarten and all that entails: following the rules, playing with others, taking turns, etc.