Digital Commons Network^™

Characterization Of Testis-Derived Mesenchymal Cells And The Hunt For Universal Stemness Markers, Myret Ghabriel

Theses and Dissertations

Mesenchymal stromal/stem cells (MSCs) are multipotent cells residing in multiple tissues with the capacity for self-renewal and differentiation into various cell types. Due to the myriad sources of MSCs the International Society for Cellular Therapy (ISCT) proposed certain criteria for their characterization. Here, we isolate adult MSCs from mouse testes and demonstrate that these testis-derived MSCs (tMSCs) follow some of the ISCT’s criteria. tMSCs expressed the MSCs surface markers CD44, CD73, and CD29 and lacked the expression of the hematopoietic cell marker CD45. Moreover, the cells displayed the capacity for self-renewal and in vitro differentiation into adipocytes. Since the isolation …

Art. 78 Petition - Fusl000094 (2021-05-27)

Art. 78 Petitions

No abstract provided.

Open Access Journals In Agriculture And Allied Sciences: A Study Based On Directory Of Open Access Journals (Doaj), Ganesan Rathinasabapathy, Veeranjaneyulu

Library Philosophy and Practice (e-journal)

This paper attempts to do a quantitative analysis of open access journals in the field of agriculture and allied sciences indexed by the Directory of Open Access Journals (DOAJ) which indexes over 17,200 peer-reviewed open access journals covering all branches of knowledge published by 130 countries in 80 languages. The study revealed that out of 17,282 open access journals indexed by the DOAJ (as on 31.12.2021), 458 journals (2.65%) are publishing articles related to agriculture and allied sciences. Brazil and Indonesia are the top countries publishing higher number of OA journals in agriculture and allied sciences with 74 titles each …

The Fierce Green Fire: Vol. 12 Issue 10, Wofford College. Department Of Environmental Studies

The Fierce Green Fire

No abstract provided.

The Beacon, February 11, 2022, The Beacon Staff

The Beacon, 2021-2022

NW students return from Romania; The future of Kepp Hall; Flettwood Mac’s album turns 45 this month; Girl-power not enough to offset forgettable story; Days at the beach brought to you in Christ Chapel; Shining a light on a theater expert with a servant heart; Unsung Heroes: music adjunct faculty; Hubbard’s sabbatical in the Bahamas; Why Americans call it soccer; Why diversity offices matter; Campus Quotes; Spotlight: Kennedy Kramer garners GPAC honors; NW wrestling takes action in meet at Sioux City; NW men’s and women’s tennis begin seasons; NW celebrates diversity in health; Super Bowl set for this Sunday in …

Noncoding-Rna-Based Therapeutics With An Emphasis On Prostatic Carcinoma-Progress And Challenges., Victor E. Nava, Pin-Yu Perera, Nirbhay Kumar, Maneesh Jain

Pathology Faculty Publications

Noncoding RNAs (ncRNAs) defy the central dogma by representing a family of RNA molecules that are not translated into protein but can convey information encoded in their DNA. Elucidating the exact function of ncRNA has been a focus of discovery in the last decade and remains challenging. Nevertheless, the importance of understanding ncRNA is apparent since these molecules regulate gene expression at the transcriptional and post-transcriptional level exerting pleiotropic effects critical in development, oncogenesis, and immunity. NcRNAs have been referred to as "the dark matter of the nucleus", and unraveling their role in physiologic and pathologic processes will provide vast …

The Usambara Knowledge Project: Place As Archive In A Tanzanian Mountain Range, Chris A. Conte

History Faculty Publications

The essay chronicles the early phases of a digital history project on landscape change in the mountains of eastern Tanzania. In collecting sources for a land and culture narrative, the project aims ultimately to create an archive that is locally produced in Tanzania and maintained by Utah State University Library's Special Collections and Archives division. The project draws on more than thirty early twentieth-century landscape photographs from the Usambara Mountains in northeastern Tanzania by Walther Dobbertin, a professional photographer living in German East Africa. In the fall of 2015, team members scouted the sites for repeat photographs. The following summer, …

Clinical Outcomes For Patients With Community-Acquired Pneumonia Are Worse In Those With A History Of Stroke, Pradeepthi Badugu, Dilip Kc, Bibodh Jung Karki, Mahder A. Tella, Vidyulata Salunkhe

The University of Louisville Journal of Respiratory Infections

Background: Stroke is one of the most prevalent neurological diseases in the United States. Community-acquired pneumonia (CAP) is the leading cause of infections in survivors of stroke. There is limited research evaluating the clinical outcomes of CAP in patients with stroke. The objective of this study was to evaluate the clinical characteristics and outcomes of hospitalized patients with CAP and a history of stroke.

Methods: This was a secondary analysis of the University of Louisville Pneumonia Study database. Patients were divided into two groups based on the presence or absence of a history of stroke. Clinical outcomes were length of …

Caloric Restriction In Humans Reveals Immunometabolic Regulators Of Health Span, O. Spadaro, Y. Youm, I. Shchukina, S. Ryu, S. Sidorov, A. Ravussin, K. Nguyen, E. Aladyeva, A. N. Predeus, S. R. Smith, E. Ravussin, C. Galban, M. N. Artyomov, V. D. Dixit

Clinical Research Faculty Publications

The extension of life span driven by 40% caloric restriction (CR) in rodents causes trade-offs in growth, reproduction, and immune defense that make it difficult to identify therapeutically relevant CR-mimetic targets. We report that about 14% CR for 2 years in healthy humans improved thymopoiesis and was correlated with mobilization of intrathymic ectopic lipid. CR-induced transcriptional reprogramming in adipose tissue implicated pathways regulating mitochondrial bioenergetics, anti-inflammatory responses, and longevity. Expression of the gene Pla2g7 encoding platelet activating factor acetyl hydrolase (PLA2G7) is inhibited in humans undergoing CR. Deletion of Pla2g7 in mice showed decreased thymic lipoatrophy, protection against age-related inflammation, …

An Efficient Deep Learning Model To Detect Covid-19 Using Chest X-Ray Images, Somenath Chakraborty, Beddhu Murali, Amal K. Mitra

Faculty Publications

The tragic pandemic of COVID-19, due to the Severe Acute Respiratory Syndrome coronavirus-2 or SARS-CoV-2, has shaken the entire world, and has significantly disrupted healthcare systems in many countries. Because of the existing challenges and controversies to testing for COVID-19, improved and cost-effective methods are needed to detect the disease. For this purpose, machine learning (ML) has emerged as a strong forecasting method for detecting COVID-19 from chest X-ray images. In this paper, we used a Deep Learning Method (DLM) to detect COVID-19 using chest X-ray (CXR) images. Radiographic images are readily available and can be used effectively for COVID-19 …

The Blueprint: #Theblackawakening

Bailey School of Music Concert Programs

The Blueprint is produced by the Black Musicians Coalition, a student group that was created to positively influence the experiences of Black musicians at Kennesaw State University. This production was created by and created for the students who struggled to find a place in the arts due to the color of their skin. This year’s show, The Blueprint: #TheBlackAwakening, is centered around the innovations and experimental/contemporary art by Black people that were and are revolutionizing society and the practice/field of art today.

The Effects Of Rosiglitazone On Task Specific Anxiety-Like Behavior And Novelty Seeking In A Model Of Chronic Adolescent Unpredictable Stress, Hannah Sexton, Nathan A. Olszewski, Mary-Louise Risher

Biomedical Sciences

Adolescence is characterized as a period of increased social behavior, risk taking, and novelty seeking, partly due to ongoing maturation in critical brain areas and the hypothalamic-pituitary-adrenal (HPA) negative-feedback system. During this period there is heightened vulnerability to stress that can drive neuro-immune-endocrine remodeling, resulting in the emergence of maladaptive behaviors that increase susceptibility to alcohol and substance abuse. Here we used a rat model to investigate the impact of chronic adolescent unpredictable stress on a battery of behavioral measures to assess anxiety, novelty seeking, risk taking, depression, and voluntary ethanol consumption while determining whether the PPARγ agonist rosiglitazone can …

The Diamond, February 11, 2022, Dordt University

Dordt Diamond

• Front Page: Full House - Kuyper Apartments to Room Seven Next Year; He Speaks for the Trees - Van Otterloo and Maintenance Department Trim the Grounds; Help Wanted - The Commons' Student Employee Shortage
• News: Dordt Launches Degree in Three Program; New Year, New Variant
• Art & Entertainment: Book of Boba Feet and Twenty Other Characters; Suing, Students Prepare for Unfinished - A Dance Concert
• Feature: Beekeeping is the Buzz on Campus and the Community; A Puritan Prayer - New Campus Ministry Leads Students in Prayer; Local Churches Take up Call to House Afghan Refugees
• Opinion …

Summer Distribution And Day Roost Characteristics Of Eastern Small-Footed Bats (Myotis Leibii) In West-Central Arkansas, Valerie Marie Kearny

Student Theses and Dissertations

Information on summer distribution and diurnal roosting is lacking for the imperiled, rock-roosting Myotis leibii, a species threatened by habitat loss and White-nose Syndrome. I aimed to 1) identify diurnal, summer roost locations in the greater Ouachita Mountains of Arkansas, and 2) determine roost habitat characteristics at the local, landscape, and roost-level scales. Using acoustic monitoring, rock searches, mist-netting, and temperature monitoring in 2019 and 2020, I found M. leibii in an aggregated distribution across the landscape roosting either solitarily or in small groups in the Rich Mountain-Black Fork Mountain, Mount Magazine, and Mount Nebo areas under sparse canopy cover, …

Migration Ecology Of Female Indiana Bats, Arin Michelle Vann

Student Theses and Dissertations

The Indiana bat (Myotis sodalis) has been listed as a federally endangered species since 1967 due to numerous natural and anthropogenic threats. Research on the species has focused on hibernacula and maternity colonies, but data gaps exist in portions of their range. To prevent further decline, migration resources need protection, but management practices are difficult to implement without having precise data on migration routes. I documented spring migration in Arkansas using aerial and ground telemetry during 2017–2018. Radio transmitters were affixed to 52 female M. sodalis during 2017 and 2018 of which 23 were successfully tracked. I located roost trees …

The Student Movement Volume 106 Issue 13: Know Your Roots: Reclaim Your Narrative, Timmy Duado, Taylor Uphus, Caryn Cruz, Qualyn Robinson, Steven Injety, Kaela Mcfadden, Solana Campbell, Nathan Mathieu, Chris Ngugi, Sion Kim, Gabriela Francisco, Denique Black, T Bruggemann, Wambui Karanja, Alannah Tjhatra, Lyle Goulbourne

The Student Movement v. 106 (2021-2022)

HUMANS

Black History Month at Andrews University: Interview with Michael Nixon, Interviewed by: Timmy Duado

Promoting Black Beauty Products as an Influencer, Interviewed by: Taylor Uphus

What does Black History Month Mean to You?, Interviewed by: Caryn Cruz

ARTS & ENTERTAINMENT

Black and Proud: An Exhibition by Courtney Saunders, Qualyn Robinson

Creative Spotlight: Michael Davis, Interviewed by: Steven Injety

Current Favorites: Black Figures in Media Edition, Kaela McFadden

Signal Boost: Abbott Elementary, Solana Campbell

NEWS

Andrews University Hosts a New Career Center, Nathan Mathieu

The Honorable Decision: News on Joe Biden's Nominee For the Highest Court in the Land, Chris …

Houston College Sport Programs’ Hurricane Harvey Communication: A Twitter Content Analysis, Chris Hanna, Robert Thompson, James T. Morton

Kinesiology and Health Science Faculty Publications

This study provides a Twitter content analysis of tweets by Houston-based Division I college sport programs during Hurricane Harvey. A content analysis was performed on the tweets appearing on the main intercollegiate athletics Twitter pages of University of Houston, Houston Baptist University, Prairie View A&M University, Rice University, and Texas Southern University in response to Hurricane Harvey. The researchers based their study on grounded theory informed by a study conducted by Inoue and Havard (2015). While this study examined tweets rather than newspaper and magazine articles like Inoue and Havard (2015), this study confirmed the theme findings in Inoue and …

Gap Junction-Dependent And -Independent Functions Of Connexin43 In Biology, Yi Zhu

Children’s Nutrition Research Center Staff Publications

Simple Summary

Connexin43 is one of the 21 members of a large protein family that forms intercellular gap junction complexes. It plays a critical role in development by allowing two adjacent cells to exchange cellular content. Mouse deletion studies have demonstrated its critical roles in many organs, including cardiac muscle, blood vessels, bone, adipose tissue and more. However, as the most expressed and most studied connexin in the family, Connexin43 surprisingly shows many gap-junction-independent roles, spanning from the forming of hemichannels, to regulating membrane trafficking, to regulating mitochondrial function. Connexin43 is also unique in the family by forming many smaller …

Sensitivity Enhancement Of An Experimental Benchtop X-Ray Fluorescence Imaging System By Deploying A Single Crystal Cadmium Telluride Detector System Optimized For High Flux X-Ray Operations, Hem Moktan, Sandun Jayarathna, Sang Hyun Cho

Faculty, Staff and Student Publications

In this work, an energy-resolving thermoelectrically cooled single crystal cadmium telluride (CdTe) detector system upgraded with the latest firmware was optimized for high x-ray flux operations using high bias voltage and fast peaking time. This detector system was deployed into an experimental benchtop x-ray fluorescence (XRF) imaging/computed tomography (XFCT) system developed for quantitative imaging of metal nanoprobes such as gold nanoparticles (GNPs). Using the firmware-upgraded and existing/old CdTe detector systems, the Compton/XRF spectra from small (8 mm diameter) GNP-containing phantoms were acquired. The phantoms were irradiated with 1.8 mm Sn-filtered 125 kVp cone beam x-rays at 24 mA. The firmware-upgraded …

Iκb-Ζ Signaling Promotes Chondrocyte Inflammatory Phenotype, Senescence, And Erosive Joint Pathology, Manoj Arra, Gaurav Swarnkar, Yael Alippe, Gabriel Mbalaviele, Yousef Abu-Amer

Open Access Publications

Osteoarthritis is a joint disease characterized by a poorly-defined inflammatory response that does not encompass a massive immune cell infiltration yet contributes to cartilage degradation and loss of joint mobility, suggesting a chondrocyte intrinsic inflammatory response. Using primary chondrocytes from joints of osteoarthritic mice and patients, we first show that these cells express ample pro-inflammatory markers and RANKL in an NF-κB dependent manner. The inflammatory phenotype of chondrocytes was recapitulated by exposure of chondrocytes to IL-1β and bone particles, which were used to model bone matrix breakdown products revealed to be present in synovial fluid of OA patients, albeit their …

Symphonic Winds, February 11, 2022, F. Mack Wood, Lauren Bobarsky

School of Music Programs

Center for the Performing Arts

February 11, 2022

Friday Evening

8:00 p.m.

Sars-Cov-2 Infection Increases Risk Of Acute Kidney Injury In A Bimodal Age Distribution, Erica C Bjornstad, Gary Cutter, Pramod Guru, Shina Menon, Isabella Aldana, Scott House, Nancy M Tofil, Catherine A St Hill, Yasir Tarabichi, Valerie M Banner-Goodspeed, Amy B Christie, Surapaneni Krishna Mohan, Devang Sanghavi, Jarrod M Mosier, Girish Vadgaonkar, Allan J Walkey, Rahul Kashyap, Vishakha K Kumar, Vikas Bansal, Karen Boman, Mayank Sharma, Marija Bogojevic, Neha Deo, Lynn Retford, Ognjen Gajic, Katja M Gist, Sccm Discovery Virus Investigators Group

Faculty, Staff and Students Publications

BACKGROUND: Hospitalized patients with SARS-CoV2 develop acute kidney injury (AKI) frequently, yet gaps remain in understanding why adults seem to have higher rates compared to children. Our objectives were to evaluate the epidemiology of SARS-CoV2-related AKI across the age spectrum and determine if known risk factors such as illness severity contribute to its pattern.

METHODS: Secondary analysis of ongoing prospective international cohort registry. AKI was defined by KDIGO-creatinine only criteria. Log-linear, logistic and generalized estimating equations assessed odds ratios (OR), risk differences (RD), and 95% confidence intervals (CIs) for AKI and mortality adjusting for sex, pre-existing comorbidities, race/ethnicity, illness severity, …

The Use Of Advanced Spectral Imaging To Reveal Nanoparticle Identity In Biological Samples, Qamar A. Alshammari, Rajasekharreddy Pala, Ayan K. Barui, Saud O. Alshammari, Andromeda M. Nauli, Nir Katzir, Ashraf M. Mohieldin, Surya M. Nauli

Pharmacy Faculty Articles and Research

Nanoparticles (NPs) have been used in drug delivery therapies, medical diagnostic strategies, and as current Covid-19 vaccine carriers. Many microscope-based imaging systems have been introduced to facilitate detection and visualization of NPs. Unfortunately, none can differentiate the core and the shell of NPs. Spectral imaging has been used to distinguish a drug molecule and its metabolite. We have recently integrated this technology to a resolution of 9 nm by using artificial intelligence-driven analyses. Such a resolution allowed us to collect many robust datapoints for each pixel of an image. Our analyses could recognize 45 spectral points within a pixel to …

Apparent Sunk Cost Effect In Rational Agents, Torben Ott, Paul Masset, Thiago S Gouvêa, Adam Kepecs

Open Access Publications

Rational decision makers aim to maximize their gains, but humans and other animals often fail to do so, exhibiting biases and distortions in their choice behavior. In a recent study of economic decisions, humans, mice, and rats were reported to succumb to the sunk cost fallacy, making decisions based on irrecoverable past investments to the detriment of expected future returns. We challenge this interpretation because it is subject to a statistical fallacy, a form of attrition bias, and the observed behavior can be explained without invoking a sunk cost-dependent mechanism. Using a computational model, we illustrate how a rational decision …

Reducing Influenza Virus Transmission: The Potential Value Of Antiviral Treatment, Frederick G Hayden, Jason Asher, Benjamin J Cowling, Aeron C Hurt, Hideyuki Ikematsu, Klaus Kuhlbusch, Annabelle Lemenuel-Diot, Zhanwei Du, Lauren Ancel Meyers, Pedro A Piedra, Takahiro Takazono, Hui-Ling Yen, Arnold S Monto

Faculty, Staff and Students Publications

Prompt antiviral treatment has the potential to reduce influenza virus transmission to close contacts, but rigorous data on the magnitude of treatment effects on transmission are limited. Animal model data indicate that rapid reductions in viral replication after antiviral treatment reduce the risk of transmission. Observational and clinical trial data with oseltamivir and other neuraminidase inhibitors indicate that prompt treatment of household index patients seems to reduce the risk of illness in contacts, although the magnitude of the reported effects has varied widely across studies. In addition, the potential risk of transmitting drug-resistant variants exists with all approved classes of …

Understanding The Modus Operandi Of Class Ii Knox Transcription Factors In Secondary Cell Wall Biosynthesis, Akula Nookaraju, Shashank K. Pandey, Yogesh Ahlawat, Chandrashekhar P. Joshi

Michigan Tech Publications, Part 1

Lignocellulosic biomass from the secondary cell walls of plants has a veritable potential to provide some of the most appropriate raw materials for producing second-generation biofuels. Therefore, we must first understand how plants synthesize these complex secondary cell walls that consist of cellulose, hemicellulose, and lignin in order to deconstruct them later on into simple sugars to produce bioethanol via fermentation. Knotted-like homeobox (KNOX) genes encode homeodomain-containing transcription factors (TFs) that modulate various important developmental processes in plants. While Class I KNOX TF genes are mainly expressed in the shoot apical meristems of both monocot and eudicot plants and are …

Potential Of C4 Tropical Grasses To Contribute In Carbon Sequestration, Environmental Security And Livelihood Opportunities Through Increased Fodder Availability, D. R. Malaviya, A. K. Roy, P. Kaushal

IGC Proceedings (1977-2023)

The world grasslands/rangeland ecosystems comprise 26% of earth’s surface and have immense ecological and economic significance. Diversity of grasslands had been a key element for their sustainability. Grasslands in India have existed as natural ecosystems for millions of years. It is a major source of income, employment and livelihood to the rural families. Owing to heavy grazing pressure, coupled with other social/anthropogenic factors, the grazing resources have fast deteriorated. The country has many old and natural grasslands with ethnic and economic value. Comprehensive ecological studies including floristic compositions, dominant species, grazing pressure and the climax/sub-climax stages of ecological succession will …

Poetic Explorations In Bill F. Ndi’S Worth Their Weight In Thorns: (De)Constructing Hegemonic National Integration And Debating Francophonecentric National Governance., Hassan Mbiydzenyuy Yosimbom

CLCWeb: Comparative Literature and Culture

This paper explores “hegemonic national integration” and “Francophonecentric national governance” in The Cameroons (TC) poetic scape. The former refers to La République du Cameroun (LRC)-British Southern Cameroons (BSC) or Southern Cameroons (SC) interconnectedness dominated by Francophones. The latter is governance that promotes a Francophone cultural superiority that refuses to see the Cameroonian world through Southern Cameroonians’ eyes. Cameroonians live in a time of enormous fragmenting “Francophonizing” and “Anglophonizing” processes. To flesh this argument out, this paper borrows critical perspectives from Benhabib’s “democratic iterations” and “deliberative democracy” and Rosenau’s “six-governance typology’ as requisites for good governance. It contends that …

Language And Betrayal: Posthuman Ethics In Kazuo Ishiguro’S Never Let Me Go, Netty Mattar

CLCWeb: Comparative Literature and Culture

Netty Mattar discusses in her article “Language and Betrayal: Posthuman Ethics in Kazuo Ishiguro’s Never Let Me Go” the complexities of ethical compassion in this biotechnological age. Mattar highlights how genetic technology creates new forms of life that dissolve the line between ‘human’ and ‘technology.’ In spite of this, contemporary ethical discussions do not take into account changing conceptions of human subjectivity and instead reinstate older assumptions about what ‘human’ is. Mattar argues that speculative fiction (SF), as a self-conscious play on signs and signification, can draw attention to how ethical responses are determined by the language we use. …

Confucianism And Folklore In Vietnamese Fantasy Short Stories: The Case Of Ghost Stories , Nguyen Thi Kim Ngan

CLCWeb: Comparative Literature and Culture

Truyền kỳ, which is a genre of fantasy short stories, was formed and developed in the historic period of medieval literature of Vietnam in the sixteenth and seventeenth centuries. Despite being derived from a similar Chinese genre, the truyền kỳ of Vietnam was the work of the endogenous development of the national fantasy short story, which was closely associated with folk literature and historical prose. However, at the time of its inception, as well as at the glorious top of this genre, truyền kỳ had never been accepted as an official genre. It was rather a metaphor for unorthodox discourse …