Digital Commons Network^™

A Diverse Flea (Shiponaptera) Assemblage From The Small Mammals Of Central New Mexico, Dianne Esther Peterson

Biology ETDs

The geographical ranges of many mammals and their associated parasites are dynamic. Comprehensive documentation of these communities over time provides a foundation for interpreting how changing environmental conditions, driven by accelerating climate change, other anthropogenic disturbances, and natural events may influence host-parasite interactions. Fleas (Order Siphonaptera) are obligate, hematophagous parasites of birds and mammals with medical interest due to their role in transmitting pathogens. From 2016 to 2019, we sampled the small mammal and associated flea communities in El Malpais National Conservation Area (El Malpais) in Cibola County, New Mexico. Among 898 mammalian specimens, 925 fleas representing 29 species were …

2022-04-12 Sga Executive Board Meeting Minutes, Morehead State University. Student Government Association.

Student Government Association Records

Meeting minutes of the Student Government Association Executive Board from April 12, 2022.

Comments The Butte Reclamation Evaluation System (Bres) Draft 2021 Field Evaluation Of Reclaimed Sites Summary Report, 2021 Bres Field Evaluation Summary Report And Technical Recommendations Proposal (Dated March 11, 2022), Nikia Greene

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Unmasking The Monster: Cathy Ames In John Steinbeck's East Of Eden, Julia N. Parker

Honors College Theses

Critics have considered Cathy Ames, the heinous villain of East of Eden, to be John Steinbeck's most complicated character. Although she is at times truly despicable, readers are prejudiced against her before she is even introduced by the narrator, who couches her entire existence as something monstrous and withholds information that might garner her any sympathy until her literal hour of death. Through a study of both Steinbeck's narrative techniques and his letters to his editor about her, we can see that she may not be as villainous as she is presented to be, but she is most certainly …

Between Us: A Short Story Cycle, Kelly C. Wilcox

Honors College Theses

“Between us” is a short story cycle that alternative between the perspectives of two sisters, Skylar and Harmony, and their love interest–Michael. This thesis explores the various ways in which people differently respond to grief and the impacts grief has on lives, relationships, and families. These stories also review the roles race and identity play in the loss of a parent, specifically when the mother is of one race and the father is of another. This thesis contains the first two stories of the longer, in-progress collection.

Washu Epigenome Browser Update 2022, Daofeng Li, Deepak Purushotham, Jessica K Harrison, Silas Hsu, Xiaoyu Zhuo, Changxu Fan, Shane Liu, Vincent Xu, Samuel Chen, Jason Xu, Shinyi Ouyang, Angela S Wu, Ting Wang

2020-Current year OA Pubs

WashU Epigenome Browser (https://epigenomegateway.wustl.edu/browser/) is a web-based genomic data exploration tool that provides visualization, integration, and analysis of epigenomic datasets. The newly renovated user interface and functions have enabled researchers to engage with the browser and genomic data more efficiently and effectively since 2018. Here, we introduce a new integrated panel design in the browser that allows users to interact with 1D (genomic features), 2D (such as Hi-C), 3D (genome structure), and 4D (time series) data in a single web page. The browser can display three-dimensional chromatin structures with the 3D viewer module. The 4D tracks, called 'Dynamic' tracks, animatedly …

Systems And Methods For Learning And Generating Movement Policies For A Dynamical System, Yu Sun, Yongqiang Huang

USF Patents

System and methods for generating a trajectory of a dynamical system are described herein. An example method includes modelling a policy from demonstration data. The method also includes generating a first set of action particles by sampling from the policy, where each of the action particles in the first set includes a respective system action, predicting a respective outcome of the dynamical system in response to each of the action particles in the first set, and weighting each of the action particles in the first set according to a respective probability of achieving a desired outcome. The method further includes …

Garnet & Black Spring 2022, University Of South Carolina, Office Of Student Media

Garnet & Black Magazine

No abstract provided.

A World Where Finance Is Democratic, Michael A. Mccarthy

Social and Cultural Sciences Faculty Research and Publications

No abstract provided.

Genomic Time Machine, Beth Potier

UNH Today Archive

No abstract provided.

Antibiotics Isolated From Soil, Aryan Hudson, Anna Arauz

2022 Student Academic Showcase

Dr. Bewick and I have partnered with the Small World Initiative to transform our Introduction to Cellular and Molecular Biology lab into an authentic Course-based Undergraduate Research Experience (CURE). Our students are isolating bacteria from soil and testing to see if they produce antibiotics. The students haven't finished collecting data yet, so I am submitting this "dummy" abstract in place of their real abstract. The students are going to vote as a class on April 5 as to who should present at the SAC. We talked to Dr. Bagley earlier in the semester and she said this would be fine. …

Interlingual Translation Of A Spanish Children's Book, Addison Haddock

2022 Student Academic Showcase

Translation is often invisible to the general population, yet it is a pivotal component of our success as a social species. The vast majority of humans could not name even a fraction of the thousands of languages present, yet many of them pervade our day-to-day lives. Consequently, a translator has the paramount role of taking an author’s original meanings and relaying this information to an audience of another language, another dialect, or another period of time. To experience this for myself, I translated the children’s story La Llorona: The Crying Woman by taking its original Spanish and transferring its meaning …

Independent - Apr. 12, 2022, Monty Stites

The Independent (1988-present)

No abstract provided.

Identification Of Small Regions Of Overlap From Copy Number Variable Regions In Patients With Hypospadias, Carter H Scott, Ina E Amarillo

Open Access Publications

Hypospadias is a common form of congenital atypical sex development that is often associated with other congenital comorbidities. Many genes have been associated with the condition, most commonly single sequence variations. Further investigations of recurrent and overlapping copy number variations (CNVs) have resulted in the identification of genes and chromosome regions associated with various conditions, including differences of sex development (DSD). In this retrospective study, we investigated the DECIPHER database, as well as an internal institutional database, to identify small recurrent CNVs among individuals with isolated and syndromic hypospadias. We further investigated these overlapping recurrent CNVs to identify 75 smallest …

Wellness Review 2021, Part 2, Brian A. Ferguson, Martin Huecker

Journal of Wellness

Introduction: This article presents Part 2 of the biannual JWellness Review of literature from 2021 (July – December). We emphasize new science and resilience initiatives published outside of JWellness that seek understanding of burnout and thriving among healthcare professionals (HCPs).

Methods: For the interval of July 1 to December 30, 2021, PubMed was queried for empirical and observational research studies, review articles, guideline summaries, letters, and editorials. Of 93 results, we reviewed methods and salient points to arrive at a final list of 48 articles for inclusion.

Literature in Review: Common themes that emerged included teamwork, EMR optimization, group decompression, …

G Protein-Coupled Receptor Kinase 5 Regulates Thrombin Signaling In Platelets Via Par-1., Kate Downes, Xuefei Zhao, Nicholas S Gleadall, Harriet Mckinney, Carly Kempster, Joana Batista, Patrick L Thomas, Matthew Cooper, James V Michael, Roman Kreuzhuber, Katherine Wedderburn, Kathryn Waller, Bianca Varney, Hippolyte Verdier, Neline Kriek, Sofie E Ashford, Kathleen E Stirrups, Joanne L Dunster, Steven E Mckenzie, Willem H Ouwehand, Jonathan M Gibbins, Jing Yang, William J Astle, Peisong Ma

Cardeza Foundation for Hematologic Research

The interindividual variation in the functional response of platelets to activation by agonists is heritable. Genome-wide association studies (GWASs) of quantitative measures of platelet function have identified fewer than 20 distinctly associated variants, some with unknown mechanisms. Here, we report GWASs of pathway-specific functional responses to agonism by adenosine 5'-diphosphate, a glycoprotein VI-specific collagen mimetic, and thrombin receptor-agonist peptides, each specific to 1 of the G protein-coupled receptors PAR-1 and PAR-4, in subsets of 1562 individuals. We identified an association (P = 2.75 × 10-40) between a common intronic variant, rs10886430, in the G protein-coupled receptor kinase 5 gene (GRK5) …

Development Of A Dual Drug-Loaded, Surfactant-Stabilized Contrast Agent Containing Oxygen, Raj Patel, Quezia Lacerda, Brian E Oeffinger, John R. Eisenbrey, Ankit K. Rochani, Gagan Kaushal, Corinne Wessner, Margaret A Wheatley

Department of Radiology Faculty Papers

Co-delivery of cancer therapeutics improves efficacy and encourages synergy, but delivery faces challenges, including multidrug resistance and spatiotemporal distribution of therapeutics. To address these, we added paclitaxel to previously developed acoustically labile, oxygen-core, surfactant-stabilized microbubbles encapsulating lonidamine, with the aim of developing an agent containing both a therapeutic gas and two drugs acting in combination. Upon comparison of unloaded, single-loaded, and dual-loaded microbubbles, size (~1.7 µm) and yield (~2 × 109 microbubbles/mL) (~1.7) were not statistically different, nor were acoustic properties (maximum in vitro enhancements roughly 18 dB, in vitro enhancements roughly 18 dB). Both drugs encapsulated above required doses …

The Interplay Between Hydrogen Sulfide And Phytohormone Signaling Pathways Under Challenging Environments, Muhammad Saad Shoaib Khan, Faisal Islam, Yajin Ye, Matthew Ashline, Daowen Wang, Biying Zhao, Zheng Qing Fu, Jian Chen

Faculty Publications

Hydrogen sulfide (H₂S) serves as an important gaseous signaling molecule that is involved in intra- and intercellular signal transduction in plant–environment interactions. In plants, H₂S is formed in sulfate/cysteine reduction pathways. The activation of endogenous H₂S and its exogenous application has been found to be highly effective in ameliorating a wide variety of stress conditions in plants. The H₂S interferes with the cellular redox regulatory network and prevents the degradation of proteins from oxidative stress via post-translational modifications (PTMs). H₂S-mediated persulfidation allows the rapid response of proteins in signaling networks …

Attribute Based Double Bounded Rough Neutrosophic Sets In Facial Expression Detection, Praba B, Pooja S S, Nethraa Sivakumar

Neutrosophic Sets and Systems

No abstract provided.

A New Copelatus With Small Eyes From The Eastern Cape Wild Coast, South Africa (Coleoptera: Dytiscidae), David T. Bilton, Musa C. Mlambo

School of Biological and Marine Sciences

No abstract provided.

Quadruped Gait And Regulation Of Apoptotic Factors In Tibiofemoral Joints Following Intra-Articular Rhprg4 Injection In Prg4 Null Mice, Daniel S. Yang, Edward E. Dickerson, Ling X. Zhang, Holly Richendrfer, Padmini N. Karamchedu, Gary A. Badger, Tannin A. Schmidt, Alger M. Fredericks, Khaled A. Elsaid, Gregory D. Jay

Pharmacy Faculty Articles and Research

Camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome leads to diarthrodial joint arthropathy and is caused by the absence of lubricin (proteoglycan 4—PRG4), a surface-active mucinous glycoprotein responsible for lubricating articular cartilage. In this study, mice lacking the orthologous gene Prg4 served as a model that recapitulates the destructive arthrosis that involves biofouling of cartilage by serum proteins in lieu of Prg4. This study hypothesized that Prg4-deficient mice would demonstrate a quadruped gait change and decreased markers of mitochondrial dyscrasia, following intra-articular injection of both hindlimbs with recombinant human PRG4 (rhPRG4). Prg4^−/− (N = 44) mice of both sexes were injected with rhPRG4 …

Voices From The Jicarilla Apache: A Critical Analysis On The Impact Of Colonization, Assimilation, On Language Loss Across Generations, Haeyalyn R. Muniz

Teacher Education, Educational Leadership & Policy ETDs

The purpose of this study was to provide a critical analysis of the impact of colonization and assimilation on the Jicarilla Apache Language through narratives across generations. From a narrative inquiry perspective, I aimed to provide personal stories from among the Jicarilla Apache about language learning environments, experiences, and perspectives. Participants shared those used in the context of everyday interaction which provided language learning and transmission, impact of assimilation policies and practices from residential schools, historical intergenerational trauma, loss of language resulting in loss of culture and ceremonies, transmission of language, and an understanding of collective ideas for additional efforts …

Can We Use Antipredator Behavior Theory To Predict Wildlife Responses To High-Speed Vehicles?, Ryan B. Lunn, Bradley Blackwell, Travis L. Devault, Esteban Fernández-Juricic

United States Department of Agriculture Wildlife Services: Staff Publications

Animals seem to rely on antipredator behavior to avoid vehicle collisions. There is an extensive body of antipredator behavior theory that have been used to predict the distance/time animals should escape from predators. These models have also been used to guide empirical research on escape behavior from vehicles. However, little is known as to whether antipredator behavior models are appropriate to apply to an approaching high-speed vehicle scenario. We addressed this gap by (a) providing an overview of the main hypotheses and predictions of different antipredator behavior models via a literature review, (b) exploring whether these models can generate quantitative …

Neutrosophic Sociogram Approach To Neutrosophic Cognitive Maps In Swift Language, R. Priya, Nivetha Martin

Neutrosophic Sets and Systems

No abstract provided.

Vcp Suppresses Proteopathic Seeding In Neurons, Jiang Zhu, Sara Pittman, Dhruva Dhavale, Jessica N Patterson, Mohamed Salman Kaleelurrrahuman, William J Buscher, Paul Kotzbauer, Albert A Davis, Conrad Weihl, Et Al.

2020-Current year OA Pubs

BACKGROUND: Neuronal uptake and subsequent spread of proteopathic seeds, such as αS (alpha-synuclein), Tau, and TDP-43, contribute to neurodegeneration. The cellular machinery participating in this process is poorly understood. One proteinopathy called multisystem proteinopathy (MSP) is associated with dominant mutations in Valosin Containing Protein (VCP). MSP patients have muscle and neuronal degeneration characterized by aggregate pathology that can include αS, Tau and TDP-43.

METHODS: We performed a fluorescent cell sorting based genome-wide CRISPR-Cas9 screen in αS biosensors. αS and TDP-43 seeding activity under varied conditions was assessed using FRET/Flow biosensor cells or immunofluorescence for phosphorylated αS or TDP-43 in primary …

Effect Of Steam Conditioning On Pecan Safety And Quality And Utilization Of Pecan Shell Extract As An Antimicrobial Coating To Maintain The Quality And Safety Of Fresh Produce, Karuna Kharel

LSU Doctoral Dissertations

Pre- and post-harvest practices can pose microbial risk on fresh produce thus, appropriate intervention strategies to inactivate foodborne pathogens without compromising quality is important. The first part of this study investigated the effect of steam conditioning on inactivating Enterococcus faecium, a surrogate for Salmonella enterica, on in-shell pecans; and second part determined the in vitro and in vivo antimicrobial efficacy of pullulan coating incorporated with pecan shell extract on produce. The treatments’ effect on quality of pecans and produce during storage were also evaluated. In-shell pecans inoculated with Enterococcus faecium (7.28±0.17logCFU/g) were treated with steam at 70°C, 80°C …

Suicide Risk And School Related Stressors In Veterinary Students, Deanna Arnold

Steeplechase: An ORCA Student Journal

Compared to the general population of the United States, veterinarians are at an increasingly higher risk for suicide. This is commonly associated with stressful work environments, long work hours, poor work-life balance, client demands and complaints, and large amounts of euthanasia procedures. While many studies have been performed to confirm the above statements, few to no studies have been done on students currently enrolled in veterinary school to assess their mental health. This study will survey graduate school students in this field and will evaluate their mental health state and risk factors towards suicide. Through comparing the results of this …

Backyard Conflict: The Effect Of Urban Development On A Population Of Eastern Box Turtles, Blakely Logsdon, Janna Knight

Liberty University Research Week

Undergraduate

Basic

The Effect Of Bpc Exposure On Ikaros And Rag-1 Gene Expression In Zebrafish, Robert Fisher, Anna Osborn, Asia Eskaros, Michael Chembars, Pierce Knepley, Thomas Russell

Liberty University Research Week

Undergraduate

Basic

Wage Inequality Amongst Artists, Raegan Christianson

INSPIRE Student Research and Engagement Conference

Presents research on hypotheses on pay differentials for artists.