Digital Commons Network^™

Early Childhood Intervention Curriculum Creation: Using Playful Project-Based Learning, Hannah Shullenberger Million

Masters Theses/Capstone Projects

The purpose of this study is to present an early intervention curriculum incorporating Project-Based Learning (PBL) and opportunities for play. The project aims to answer the questions: What does a Project-Based Learning curriculum model look like in high quality early childhood special education? How does PBL curriculum work in conjunction with play? The created curriculum answers these questions based on a review of research and guidance from three theoretical frameworks: a Vygotskian Tools of the Mind approach (Bodrova & Leong, 1996), implementation of PBL in early childhood (Lev et al., 2020) and the early intervention Building Blocks framework (Sandall et …

Spartan Daily, April 14, 2022, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2022

Volume 158, Issue 31

Q&A With Madeline Mcmahan (Mfa Painting), Madeline Mcmahan

Q & A Interviews with Art Students

No abstract provided.

Molecular Approaches For The Validation Of The Baboon As A Nonhuman Primate Model For The Study Of Zika Virus Infection, Emma Mask, V. L. Hodara, Jessica E. Callery, L. M. Parodi, V. Obregon-Perko, S. Yagi, J. Glenn, P. Frost, E. Clemmons, J. L. Patterson, L. A. Cox, Luis D. Giavedoni

Biology Faculty Research

Nonhuman primates (NHP) are particularly important for modeling infections with viruses that do not naturally replicate in rodent cells. Zika virus (ZIKV) has been responsible for sporadic epidemics, but in 2015 a disseminated outbreak of ZIKV resulted in the World Health Organization declaring it a global health emergency. Since the advent of this last epidemic, several NHP species, including the baboon, have been utilized for modeling and understanding the complications of ZIKV infection in humans; several health issues related to the outcome of infection have not been resolved yet and require further investigation. This study was designed to validate, in …

Impaired Microcirculatory Function, Mitochondrial Respiration, And Oxygen Utilization In Skeletal Muscle Of Claudicating Patients With Peripheral Artery Disease, Song-Young Park, Elizabeth J. Pekas, Cody Anderson, Tyler N. Kambis, Paras K. Mishra, Molly Schieber, Tesean Wooden, Jonathan R. Thompson, Kyung-Soo Kim, Iraklis Pipinos

Health and Kinesiology Faculty Publications

Peripheral artery disease (PAD) is an atherosclerotic disease that impairs blood flow and muscle function in the lower limbs. A skeletal muscle myopathy characterized by mitochondrial dysfunction and oxidative damage is present in PAD; however, the underlying mechanisms are not well established. We investigated the impact of chronic ischemia on skeletal muscle microcirculatory function and its association with leg skeletal muscle mitochondrial function and oxygen delivery and utilization capacity in PAD. Gastrocnemius samples and arterioles were harvested from patients with PAD (n = 10) and age-matched controls (Con, n = 11). Endothelium-dependent and independent vasodilation was assessed in response …

Uab Joins International Drug Trial For Amyotrophic Lateral Sclerosis, Alicia Rohan

Browse All News

No abstract provided.

Settler-Author Allyship In Centering Indigenous Ecologies: Communal Will Through Collective Environmental Guilt In This Tender Land And Caleb's Crossing, Elena Marie Arana

Theses and Dissertations

The January 2021 edition of PMLA housed an entire cluster on "Indigenous Literatures and the Anthropocene," in which at least four of the eight non-Indigenous contributors directly addressed and supported a call for learning from and collaborating with Indigenous voices. The unanimity of the discussion dissolves somewhat drastically when considering exactly how this should be done, leading Melanie Taylor to voice one of the framing questions of the cluster: "If it is increasingly clear that not all members of Anthropos are equal drivers of the Anthropocene, and that not all are uniformly compromised by its havoc, how can we begin …

Covid-19 And The Americans With Disabilities Act: When Might The Disease Be Considered A Disability For Which Employees Have Legal Protections In The Workplace?, Kimberly J. Jones, Emma M. Feeney

Denver Law Review

Since the coronavirus pandemic began in the United States in early 2020, employers, legal practitioners, federal and state agencies, and the courts have wrangled with whether and in what circumstances workers impacted by COVID-19 (COVID) may have legal protections at work. Because the virus is novel, case law and other legal authorities are scarce. However, these questions are likely to persist well into the future as the virus continues to evolve and the pandemic rages on. This Article explores whether and in what circumstances courts in the Tenth Circuit are likely to treat COVID as a “disability” under the Americans …

The Comment, April 14, 2022, Bridgewater State University

The Comment

No abstract provided.

The World, Rebecca Dawn Billings

Theses and Dissertations

A poem comes into the world when an obsession takes hold of a person who must write about it. These twenty-eight original poems are products of obsession and pleasure.

Mucormycosis: Covid-19 And Corticosteroids, Mittal Savaliya, Nivedita Jha, Steven B Lippmann

The University of Louisville Journal of Respiratory Infections

No abstract provided.

Reframing Technology-Facilitated Gender-Based Violence At The Intersections Of Law & Society, Jane S. Bailey, Carys Craig, Suzie Dunn, Sonia Lawrence

Articles & Book Chapters

This special issue of the Canadian Journal of Law and Technology focuses on the growing problem of technology-facilitated gender-based violence (TFGBV): an expansive, dynamic, and rapidly evolving phenomenon that Jane Bailey and Carissima Mathen have defined as “a spectrum of behaviours carried out at least in some part through digital communications technologies, including actions that cause physical or psychological harm.” The collection of articles in this issue offers multi-disciplinary insights on TFGBV by bringing together the work of emerging scholars in information and media studies, communications, and law. This approach reflects our firm belief that in order to be meaningful …

Acknowledging The Relevance Of Elephant Sensory Perception To Human–Elephant Conflict Mitigation, Robbie Ball, Sarah L. Jacobson, Matthew S. Rudolph, Miranda Trapani, Joshua M. Plotnik

Publications and Research

Elephants are well known for their socio-cognitive abilities and capacity for multi-modal sensory perception and communication. Their highly developed olfactory and acoustic senses provide them with a unique non-visual perspective of their physical and social worlds. The use of these complex sensory signals is important not only for communication between conspecifics, but also for decisions about foraging and navigation. These decisions have grown increasingly risky given the exponential increase in unpredictable anthropogenic change in elephants’ natural habitats. Risk taking often develops from the overlap of human and elephant habitat in Asian and African range countries, where elephants forage for food …

“From The Beginning Of Time”: The Colonial Reconfiguration Of Native Habitats And Indigenous Resource Practices On The British Columbia Coast, Chief Adam Dick (Kwaxsistalla Wathl’Thla), Daisy Sewid-Smith (Mayanilth), Kim Recalma-Clutesi, Douglas Deur, N.J. Turner (Galitsimġa)

Anthropology Faculty Publications and Presentations

Indigenous Peoples’ lives, cultures, and values are defined largely by their long-term relationships with the lands, waters, and lifeforms of their territories. Their stories, names, ceremonies, and connections with the plants and animals on which they have depended over countless generations are cornerstones of their knowledge systems, systems of governance and decision-making, traditions of intergenerational knowledge transmission, and values and responsibilities associated with natural and human domains alike. For First Nations of North America’s Northwest Coast, as for many other Indigenous Peoples, the arrival of European newcomers disrupted both the natural world and associated cultural practices in interconnected ways. The …

The Proposal For The Development Of A Minimal Viable Product (Mvp) Repository Website Containing Authentic Texts In Video Format For The Use Of Language Teachers In The Twenty-First Century, Rute Maria Baptista

Theses and Dissertations

This thesis project proposed the building of a website as a repository of authentic texts in video format for teaching foreign or second languages. The project planned the building of a minimal viable product or MVP with authentic videos both in English and Spanish, organized by the ACTFL levels with particular attention to the Intermediate level. Data were collected from a survey of 42 respondents in the United States and 89 combined from Spain and Mexico. The responses collected suggest that there is a need for this MVP. Additionally, the data indicated which features were most wanted by these teachers. …

Improving Belonging Through Occupation In Individuals Within The Substance Use Disorder Population, Michelle Perkins, Susan Macdermott

Spring 2022 Virtual OTD Capstone Symposium

This capstone project focused on improving belonging through occupation in individuals within the substance use disorder population. Based on site-based needs assessment findings and informed by the Recovery Model and the Doing, Being, Belonging, and Becoming framework, the Elevate 4-week pilot program was created. The Elevate program successfully demonstrated the feasibility of improving belonging through occupations, as evidenced by changes in pre and post-program client questionnaire scores. The client’s self-report scores in sense of belonging, satisfaction of belonging, and connection to housemates and staff demonstrated noticeable improvement. While the Elevate program demonstrated noticeable improvement in participants’ sense of belonging, satisfaction …

Synthesis, Characterization, And In Vivo Cytokinome Profile Of Il-12-Loaded Plga Nanospheres, Ryan A. Lacinski, Justin E. Markel, Jabeen Noore, Hillary G. Pratt, Brock A. Lindsey

Faculty & Staff Scholarship

We report the successful encapsulation and elution of recombinant murine IL-12 (rmIL-12) from poly(lactide-co-glycolic) acid (PLGA) nanospheres (IL-12-NS) synthesized using the double emulsion/solvent evaporation (DESE) technique with microsphere depletion through ultracentrifugation. Images obtained with scanning electron microscopy (SEM) showcased a characteristic spherical shape with a mean particle diameter of and zeta potential of . These values suggest minimal flocculation when in solution, which was reflected in an in vivo biodistribution study that reported no observed morbidity/mortality. Encapsulation efficiency (EE) was determined to be with average particle concentration obtained per batch of particles/mL. Disparate zeta (ζ) potentials obtained from …

The Montclarion April 14, 2022, The Montclarion

The Montclarion

Student Newspaper of Montclair State University

Mohs Micrographic Surgery For Dermatofibrosarcoma Protuberans In 15 Patients: The University Of Arkansas For Medical Sciences Experience, Blake St. Clair, Abigale Clark, Benjamin Rollins, Thomas A. Jennings

Student Publications

Background: Dermatofibrosarcoma protuberans (DFSP) is an uncommon, locally aggressive malignancy with wide local excision (WLE) or Mohs micrographic surgery (MMS) representing the treatment of choice. This article illustrates the experience of a single academic institution in treating DFSP with MMS and adds two particularly large, difficult closures of the glabella/central forehead and sternum to the body of literature.

Objective: To report the results of 15 patients with DFSP treated with MMS over a five-year period by a single Mohs surgeon at the University of Arkansas for Medical Sciences (UAMS).

Methods: A total of 15 patients between the ages of 16 …

Medical Manikin Augmented Reality Simulation (M2ars), Pauline Delacruz, Jacob Gibson, Daniel Howard, Jaclyn Peacock, Kendall Robbins

Modeling, Simulation and Visualization Student Capstone Conference

The Medical Manikin Augmented Reality Simulation (M2ARS) is an augmented reality simulation application built for the Microsoft HoloLens 2 that uses the principles of anatomy transfer to overlay human anatomical structures onto a medical manikin digitally. These structures currently consist of the skeletal, muscular, and circulatory systems. In addition, a model of the lungs and an animated heart are also available within the simulation. M2ARS allows the user to view these structures in a manner that is both visually and spatially accurate to the human body. This application contains two modes; an augmented reality mode, which uses a manikin, and …

A Preliminary Comparative Study Of Molecular Visualization Software For Education, Ruoming Shen

Modeling, Simulation and Visualization Student Capstone Conference

Chemistry and biology are sciences vital for understanding metabolic processes, developing disease treatments, and improving environmental conditions. With extensive knowledge of biochemistry, we can take advantage of a material’s unique chemical composition and properties in various applications. Visualization software is essential for analyzing complex chemical and biological structures and predicting their interactions with each other. This paper presents a preliminary study of three open source molecular visualization software tools - Visual Molecular Dynamics (VMD), Jmol, and Mol*, and evaluates their strengths and deficiencies. This paper utilizes the March Molecule of the Month, Vascular Endothelial Growth Factor (VEGF), from the Protein …

Implementing Virtual Reality Technology For Supporting Autonomous Vehicle-Pedestrian Behavioral And Interaction Research, Zizheng Yan

Modeling, Simulation and Visualization Student Capstone Conference

The deployment of autonomous vehicles (AVs) has been expected to significantly reshape traffic safety on roads. However, there is still a relatively long journey to achieve high-level autonomy and the safety level of interaction between AVs and vulnerable road users (e.g., pedestrians, cyclists, or passengers) is still unclear due to very limited data and field tests. The main objective of this paper is to propose a high-fidelity human-in-the-loop simulation that is capable of supporting AV-pedestrian interactions by coupling an advanced AV simulator with virtual reality technology. The prototype of the extended simulation framework has been developed and demonstrated with experimental …

A Photography-Based, Social Media Walking Intervention Targeting Autonomous Motivations For Physical Activity: Semistructured Interviews With Older Women, Jason R Bentley, Karen M Basen-Engquist, Debbe Thompson, Elena Volpi, Elizabeth J Lyons

Faculty, Staff and Students Publications

BACKGROUND: Older adult women are at risk for negative health outcomes that engaging in sustained physical activity can help prevent. However, promoting long-term maintenance of physical activity in this population has proven to be a challenge. Increasing autonomous motivations (ie, intrinsic, integrated, and identified regulations) for physical activity may facilitate enduring behavior change. Digitally delivered games for health that take a celebratory technology approach, that is, using technology to create new ways to experience valued behaviors and express valued beliefs, may be a useful way to target autonomous motivations for physical activity. Formative research with the target population is needed …

Cs1 Car-T Targeting The Distal Domain Of Cs1 (Slamf7) Shows Efficacy In High Tumor Burden Myeloma Model Despite Fratricide Of Cd8+Cs1 Expressing Car-T Cells, Julie O'Neal, Julie K Ritchey, Matthew L Cooper, Jessica Niswonger, L Sofía González, Emily Street, Michael P Rettig, Susan W Gladney, Leah Gehrs, Ramzi Abboud, Julie L Prior, Gabriel J Haas, Reyka G Jayasinghe, Li Ding, Armin Ghobadi, Ravi Vij, John F Dipersio

2020-Current year OA Pubs

Despite improvement in treatment options for myeloma patients, including targeted immunotherapies, multiple myeloma remains a mostly incurable malignancy. High CS1 (SLAMF7) expression on myeloma cells and limited expression on normal cells makes it a promising target for CAR-T therapy. The CS1 protein has two extracellular domains - the distal Variable (V) domain and the proximal Constant 2 (C2) domain. We generated and tested CS1-CAR-T targeting the V domain of CS1 (Luc90-CS1-CAR-T) and demonstrated anti-myeloma killing in vitro and in vivo using two mouse models. Since fratricide of CD8 + cells occurred during production, we generated fratricide resistant CS1 deficient Luc90- …

Kenyon Collegian - April 14, 2022

The Kenyon Collegian

No abstract provided.

Guided Hybrid Modified Simulated Annealing Algorithm For Solving Constrained Global Optimization Problems, Ali Wagdy Mohamed, Salem Mahdi, Khalid Abdulaziz Alnowibet, Mahmoud El-Alem

Faculty Journal Articles

In this paper, a hybrid gradient simulated annealing algorithm is guided to solve the constrained optimization problem. In trying to solve constrained optimization problems using deterministic, stochastic optimization methods or hybridization between them, penalty function methods are the most popular approach due to their simplicity and ease of implementation. There are many approaches to handling the existence of the constraints in the constrained problem. The simulated-annealing algorithm (SA) is one of the most successful meta-heuristic strategies. On the other hand, the gradient method is the most inexpensive method among the deterministic methods. In previous literature, the hybrid gradient simulated annealing …

Control Of Orthodontic Tooth Movement By Nitric Oxide Releasing Nanoparticles In Sprague-Dawley Rats, Derrick Crawford, Tommy C. Lau, Megan C. Frost, Nan E. Hatch

Michigan Tech Publications, Part 1

Orthodontic treatment commonly requires the need to prevent movement of some teeth while maximizing movement of other teeth. This study aimed to investigate the influence of locally injected nitric oxide (NO) releasing nanoparticles on orthodontic tooth movement in rats. Materials and Methods: Experimental tooth movement was achieved with nickel-titanium alloy springs ligated between the maxillary first molar and ipsilateral incisor. 2.2 mg/kg of silica nanoparticles containing S-nitrosothiol groups were injected into the mucosa just mesial to 1st molar teeth immediately prior to orthodontic appliance activation. NO release from nanoparticles was measured in vitro by chemiluminescence. Tooth movement was measured using …

Colin Evers, Piano, In A Graduate Recital, April 14, 2022 [Program], University Of Northern Iowa. School Of Music.

Music Recital Programs

Program of a music recital given by faculty, students, or guest artists from the School of Music at the University of Northern Iowa.

Surgical Intervention With Adjunctive Cryotherapy For Canine Conjunctival Hemangiosarcomas Versus Hemangiomas, Lisa M. Hoard

Biomedical Engineering ETDs

Conjunctival hemangiomas and hemangiosarcomas are vascular tumors that affect the tissue in the eyes of canines. While relatively rare, these tumors can be costly to remove, and have a possibility of recurrence. Therefore, more understanding of the nature of these tumors and recurrence rates is of importance to the veterinary ophthalmologist. To date, there is limited data in the literature (2 retrospective studies) that examine the development, treatment, and recurrence of these vascular tumors; furthermore, the analyses do not examine the potential recurrence of tumors after treatment with therapies adjunctive to surgery (such as cryoablation, radiotherapy, and others). For this …

Prenatal Alcohol Exposure Alters The Expression Of Mir-150-5p And Its Vascular Targets In Brain Microvascular Endothelial Cells And Disrupts The Structure And Integrity Of The Developing Brain Vasculature, Gabriela Perales

Biomedical Sciences ETDs

Prenatal alcohol exposure (PAE) can result in fetal alcohol spectrum disorders (FASD) causing developmental disabilities and neurocognitive deficits. The effects of PAE on neuronal-specific alterations during brain development have been studied extensively but the contribution of the brain vascular system is limited. Recent studies have determined that there are alterations to the cortical microvasculature during PAE, posing new questions about the role of the vasculature and the development of PAE-mediated neurocognitive deficits. Even less studied are the molecular mechanisms that contribute to changes in the vasculature during PAE. As microRNAs (miRNAs) are master post-transcriptional regulators capable of regulating many mRNA …