Digital Commons Network^™

Biob 109n.00: Montana Ecosystems, Gregory D. Peters

University of Montana Course Syllabi, 2026-2030

No abstract provided.

Phl 112e.01: Introduction To Ethics And The Environment, Christopher J. Preston

University of Montana Course Syllabi, 2026-2030

No abstract provided.

Salary Report, 2026 February, Eastern Michigan University

EMU Salary Reports

No abstract provided.

How To Measure, Analyze, And Interpret Age-Related Changes In Caenorhabditis Elegans: Lessons For Mechanistic And Evolutionary Theories Of Aging, Zuzana Kocsisova, Brian M. Egan, Andrea Scharf, Xavier Anderson, Franziska Pohl, Aaron Anderson, Kerry Kornfeld

Biological Sciences Faculty Research & Creative Works

Aging is characterized by progressive degenerative changes in tissue organization and function, some of which increase the probability of mortality. Major goals of aging research are to elucidate the series of events that cause degenerative changes, and to identify environmental, pharmacological, and genetic factors that influence these changes; this information might lead to new strategies to extend health span and lifespan. Mechanistic studies of aging depend on accurate and precise descriptions of age-related changes, since these descriptions define the aging phenotype. Here, we review studies that describe age-related changes in C. elegans, including measurements of integrated functions such as behavior …

Hollywood’S Toughest Stunt Clan Comes From Gossau, Canton St. Gallen:, Roland Schäfli

Swiss American Historical Society Review

Hans Epper from eastern Switzerland conquered Hollywood as a stuntman in the 1930s. His descendants continue to perform death-defying stunts for Quentin Tarantino and Steven Spielberg to this day. A family history like something out of a movie.

When Hans Epper arrived in New York on Whit Monday (the day after Pentecost) in 1926, he gave his name as “John” to the immigration authorities.

He discarded “Hans” just as he wanted to discard his origins: his past in the eastern Swiss municipality of Gossau. An official at the town hall of the industrial village in St. Gallen had scribbled “Off …

Numerical Investigation Of A Dual-Mode Shape Memory Alloy Stent Enabling Secondary Expansion Via Focused Ultrasound: A Potential Strategy For Correcting In-Stent Restenosis, Stephen Asare, Lucinda Duncan, Josiah Owusu-Danquah, Brian L. Davis

Civil and Environmental Engineering Faculty Publications

Coronary stent implantation is an invasive procedure performed to correct atherosclerosis. The aftermath of this procedure is identified with neointimal hyperplasia, which contributes to in-stent restenosis (ISR), and thus remains a significant clinical challenge. This study introduces a novel, noninvasive conceptual approach for addressing ISR through the thermal activation of shape memory alloy (SMA) stent using focused ultrasound (FU) in a controlled manner to restore luminal patency. COMSOL Multiphysics and ABAQUS finite element software were employed to perform the numerical modeling to simulate the thermal and mechanical responses of the SMA stent integrated into the arterial wall. After 15 s …

Bch 482.01: Advanced Biochemistry Ii, J. Stephen Lodmell

University of Montana Course Syllabi, 2026-2030

No abstract provided.

Texture Density Discrimination Is More Precise Than Number Discrimination, Frank H. Durgin, Nichole Suero Gonzalez , '27, P. Wen, A. C. Huk

Psychology Faculty Works

Density information is a possible primitive for the perception of numerosity. It has been argued, however, that the perception of numerosity is more precise than density perception at low numbers, whereas density is more precise for high numbers. An interpretive problem with the stimuli used to make those claims is that actual stimulus density was often mis-specified owing to an ambiguity regarding the idealized versus actual filled area. This ambiguity had the effect of underestimating density precision at low numerosities. Here we used a novel method of stimulus generation that allows us to accurately specify stimulus density independent of patch …

To Hold Or Sell Breeding Cattle In The Rangelands, Department Of Primary Industries And Regional Development, Western Australia

Animal production and livestock factsheets

In a dry season where feed, water and finances are limited, removing less productive animals as soon as possible is a good option. This will free up feed for more productive animals and help preserve ground cover.

This page provides some of the information and a process for making decisions about holding or selling breeding cattle.

Subsidiarity Municipalism In Action: On Vincent V. Adams, Gregory E. Louis

University of Michigan Journal of Law Reform Caveat

Building on the author’s recent article Protecting Commoners’ Goods: Pluralist Coexistence Through the Common Good Constitution’s Subsidiarity Municipalism (PCG), this Essay deconstructs the recent New York appellate opinion in Vincent v. Adams. That case reverses a trial court opinion that PCG criticizes as an example of how current law misunderstands the proper relationship between local government and federal and state authorities. This Essay uses the appellate court decision in Vincent v. Adams to reinforce PCG’s thesis of subsidiarity municipalism, to offer another illustration of subsidiarity municipalism’s progressive potential, and to suggest how subsidiarity municipalism can inform the relationship between …

Fisheries Management Paper No. 311: West Coast Deep Sea Crustacean Resource Harvest Strategy, Department Of Primary Industries And Regional Development, Western Australia

Fisheries Management Papers

Harvest strategies for Western Australia’s (WA) aquatic resources are formal documents developed by the Department of Primary Industries and Regional Development (DPIRD, the Department) to support decision-making processes that ensure the outcomes are consistent with the principles of Ecologically Sustainable Development (ESD; Fletcher 2002a) and Ecosystem Based Fisheries Management (EBFM; Fletcher et al. 2012). Harvest strategies are a key component of all contemporary fishery management systems and a requirement for certification under the Marine Stewardship Council (MSC). The objectives of ESD are reflected in the objectives of the Fish Resources Management Act 1994 (FRMA).

This West Coast Deep Sea Crustacean …

Life-Extending Interventions Do Not Necessarily Result In Compression Of Morbidity: A Case Example Offering A Robust Statistical Approach., Deependra K Thapa, Wasiuddin Najam, Erik S Parker, Xi Rita Wang, Daniel L Smith, Ufuk Beyaztas, James F Nelson, Steven N Austad, Gary Churchill, David B Allison

Faculty Research 2026

Despite extensive research on life-extending interventions, rigorous statistical techniques to determine their impact on compression of morbidity (CoM) are rarely used. We present a case example of an analytical method for examining the effect of life-extending dietary interventions on CoM by comparing the rates of decline in vitality and survival toward the end of life. Using data from previous experimental studies in mice, we calculated the average rate of vitality decline by fitting exponential decay models to individual vitality trajectories and compared this rate with the rate of survival decline estimated from Cox proportional hazards model. The results showed that, …

Nrn1 As A Therapeutic Target For Alzheimer's Disease., Derian A Pugh, Gregory Cary, Kelsey M Greathouse, Lauren C Nassour-Caswell, Emma L Hobby, Nicholas T Seyfried, Jeremy H Herskowitz

Faculty Research 2026

INTRODUCTION: Neuritin-1 (NRN1) was identified as a synaptic protein associated with cognitive resilience to Alzheimer's disease (AD).

METHODS: Target risk score and cell type expression profiles were generated for NRN1 using methods developed by the Emory-Sage-SGC-JAX Target Enablement to Accelerate Therapy Development for Alzheimer's Disease (TREAT-AD) Center and Seattle Alzheimer's Disease Brain Cell Atlas (SEA-AD). Antibody characterization was conducted using Western blots and densitometry to assess the relative protein abundances of NRN1 in rodents, humans, and cell models.

RESULTS: NRN1 has a TREAT-AD target risk score of 3.29 out of 5. Based on single-nucleus RNA sequencing from SEA-AD, NRN1 expression …

Beyond The Streetlight: A Treat-Ad Perspective On Where To Find New Alzheimer's Targets., Gregory Cary, Jesse C Wiley, Gregory W. Carter, Allan I Levey

Faculty Research 2026

Despite extensive investments in Alzheimer's disease (AD) therapeutic development, progress toward effective interventions remains modest. The landscape of potential novel therapeutic strategies is rapidly growing, but prioritization, validation, and tools to advance targets to trial are lagging. The Target Enablement to Accelerate Therapy Development for Alzheimer's Disease (TREAT-AD) consortium has integrated systems-level data from large-scale studies profiling thousands of human brains, yielding target-specific risk scores that partition disease risk into discrete biological domains and enable data-driven target interrogation. Here, we compared clinical trial targets with top-ranked TREAT-AD targets and found a limited overlap as well as differences in the biology …

Pericardial Effusion, Children's Mercy Kansas City

Clinical Pathways

No abstract provided.

Deepfake Liability, Ayelet Gordon-Tapiero, Yotam Kaplan, Gideon Parchomovsky

North Carolina Law Review

No abstract provided.

Life-Extending Interventions Do Not Necessarily Result In Compression Of Morbidity: A Case Example Offering A Robust Statistical Approach., Deependra K Thapa, Wasiuddin Najam, Erik S Parker, Xi Rita Wang, Daniel L Smith, Ufuk Beyaztas, James F Nelson, Steven N Austad, Gary Churchill, David B Allison

Faculty Research 2026

Despite extensive research on life-extending interventions, rigorous statistical techniques to determine their impact on compression of morbidity (CoM) are rarely used. We present a case example of an analytical method for examining the effect of life-extending dietary interventions on CoM by comparing the rates of decline in vitality and survival toward the end of life. Using data from previous experimental studies in mice, we calculated the average rate of vitality decline by fitting exponential decay models to individual vitality trajectories and compared this rate with the rate of survival decline estimated from Cox proportional hazards model. The results showed that, …

Nrn1 As A Therapeutic Target For Alzheimer's Disease., Derian A Pugh, Gregory Cary, Kelsey M Greathouse, Lauren C Nassour-Caswell, Emma L Hobby, Nicholas T Seyfried, Jeremy H Herskowitz

Faculty Research 2026

INTRODUCTION: Neuritin-1 (NRN1) was identified as a synaptic protein associated with cognitive resilience to Alzheimer's disease (AD).

METHODS: Target risk score and cell type expression profiles were generated for NRN1 using methods developed by the Emory-Sage-SGC-JAX Target Enablement to Accelerate Therapy Development for Alzheimer's Disease (TREAT-AD) Center and Seattle Alzheimer's Disease Brain Cell Atlas (SEA-AD). Antibody characterization was conducted using Western blots and densitometry to assess the relative protein abundances of NRN1 in rodents, humans, and cell models.

RESULTS: NRN1 has a TREAT-AD target risk score of 3.29 out of 5. Based on single-nucleus RNA sequencing from SEA-AD, NRN1 expression …

Beyond The Streetlight: A Treat-Ad Perspective On Where To Find New Alzheimer's Targets., Gregory Cary, Jesse C Wiley, Gregory W. Carter, Allan I Levey

Faculty Research 2026

Despite extensive investments in Alzheimer's disease (AD) therapeutic development, progress toward effective interventions remains modest. The landscape of potential novel therapeutic strategies is rapidly growing, but prioritization, validation, and tools to advance targets to trial are lagging. The Target Enablement to Accelerate Therapy Development for Alzheimer's Disease (TREAT-AD) consortium has integrated systems-level data from large-scale studies profiling thousands of human brains, yielding target-specific risk scores that partition disease risk into discrete biological domains and enable data-driven target interrogation. Here, we compared clinical trial targets with top-ranked TREAT-AD targets and found a limited overlap as well as differences in the biology …

The Scope And Impact Of Walking The Talk For Dementia 2024, Sherril B. Gelmon, Kate Irving, Walter Dawson, Jonathan Adrián Zegarra-Valdivia, Lingani Mbakile-Mahlanza, Fernando Aguzzoli-Peres

Institute on Aging Publications

Walking the Talk for Dementia (WTD) is a global educational initiative integrating a walk along the Camino de Santiago with a symposium to combat dementia stigma, raise awareness, and foster inclusion.

2026-02-01 Caudill Connection, Morehead State University. Caudill College Of Arts, Humanities And Social Sciences.

Caudill Connection

Caudill Connection newsletter for January of 2026.

Unl Emeriti And Retirees Association Newsletter, February 2026

UNL Emeriti and Retirees Association: Newsletters and Other Materials

University of Nebraska-Lincoln Emeriti and Retirees Association Newsletter, February 2026>

Message from the ERA President, Vicki Highstreet

Thank you to former ERA President, Pam Edwards

Welcome to new members

Introducing a new ERA member: Ellen Paparozzi

ERA 65th anniversary

Organizational development plan

Funding opportunity

Wisherd awards

Wake up your well-being

mini-grant update

State of long-term care in Nebraska

Announcements and notices

Upcoming programming

Programming recap

Memory moments

Food Systems Advocacy In The Global South: A Framework And Pilot In India, Anita Rajan, Jah Ying Chung, Allison Troy Phd

General - Animal Protection

This exploratory study forms the first stage of a broader project to improve the cultural and strategic alignment of animal advocacy efforts across the Global South. It seeks to develop a practical framework that helps advocates and funders identify and integrate key contextual factors into campaign design. The project will begin with India as a pilot site, with potential for future replication in other countries.

Finding Luis: A Creative Nonfiction Account Of Law & Society, Jason M. Leggett

Dissertations, Theses, and Capstone Projects

This essay explores the contradictions in legal theory and human experience through creative nonfiction. Its main purpose is to argue that a truly just society requires acknowledging the profound influence of individual narratives on the law. This is supported by blending personal narratives, critical analysis, and philosophical inquiry to reveal the gap between codified law and lived realities for marginalized individuals. This unique Legal Poetics methodology employs a series of six vignettes, such as the author's and Luis's shared experiences with traumatic brain injury and the denial of justice, as data. By integrating autoethnography, law as narrative, and performativity theories, …

Mind The Gap: Morphological Defectivity And Suffixal Competition In Polish, Szymon E. Zuberek

Dissertations, Theses, and Capstone Projects

This study investigates morphological defectivity and suffixal competition in the genitive singular of Polish masculine inanimate nouns. Drawing on survey-based grammaticality judgments from native speakers, it examines how respondents select between the suffixes -a and -u or reject both as unacceptable, thereby signaling defectivity. Mixed-effects logistic regressions revealed that defectivity was rare overall but patterned systematically by age, education, and region, with additional baseline variability across lexical items. Suffix choice showed a strong preference for -a, modulated by age, education, and region, with additional baseline variability across lexical items. These findings inform our understanding of paradigm structure, sociolinguistic variation, and …

4e-Bp1 Differentially Regulates Translation Of A Subset Of Human Mrnas, Mehreen Mahbub

Dissertations, Theses, and Capstone Projects

Elevated levels of eukaryotic initiation factor 4E-binding protein 1 (4E-BP1) influence cap-independent translation by forming a complex with eukaryotic initiation factor 4E (eIF4E) (eIF4E•4E-BP1). Certain mRNAs—including those encoding hypoxia-inducible factor-1α (HIF-1α), fibroblast growth factor-9 (FGF-9), and two isoforms of tumor suppressors, p53 (p53_A, and p53_B)—contain structured 5’untranslated regions (UTRs) that enable translation either via cap-independent translation enhancer (CITE)-like or internal ribosomal entry site (IRES)-like mechanisms. However, how 4E-BP1 modulates these mechanisms remains unclear. Using fluorescence-based anisotropy assays, we showed that the eIF4E•4E-BP1 binds more tightly to the 5’ m⁷G-cap of these mRNAs than eIF4E …

Computational And Functional Characterization Of Terebrid Venom Peptides, Favour T. Achimba

Dissertations, Theses, and Capstone Projects

Venom peptides represent a natural repertoire of bioactive compounds that are potent modulators of ion channels. Teretoxins, venom peptides from terebrid snails, remain underexplored despite their structural and functional diversity. This thesis is the first to comprehensively explore the structure and function of teretoxins using a comparative computational sequence and structure model followed by experimental assays. The majority of the functional focus has been on identifying the ion channel molecular targets of uncharacterized teretoxins. Teretoxins, like other venom peptides, are hypothesized to manipulate the cellular function of a diversity of ion channels. Dysregulation of ion channels leads to several …

A Work On/Of Language: Lyric And The Care Of The Self, Evan M. Knight

Dissertations, Theses, and Capstone Projects

Drawing on Michel Foucault’s work on the Ancient Greek practice of the care of the self, this dissertation argues that lyric poetry is a technology of the self: an ethical practice that creates potential for self-transformation through the demands it places on language and modes of attention. Lyric thus maintains a form of truth discourse overshadowed by the Cartesian conception of truth as propositional and method-driven. Unlike contemporary self-care, the care of the self, as the original Greek epimeleia heautou entails, is care inflected by concern and anxiety: the practicing subject places her thoughts, assumptions, ways of being, and—in the …

Molding The Mosaic: Progressive Coalition Formation In The 2021 New York City Council Elections, Sam Goodson

Dissertations, Theses, and Capstone Projects

The 2021 New York City Council primaries marked a decisive breakthrough for the city’s progressive left. A cohort of democratic-socialist and socialist-adjacent candidates won office across multiple boroughs, dramatically expanding the size and influence of the left flank of the council. This dissertation analyzes those victories and argues that they constituted a hinge moment in the construction of a progressive governing regime in New York City, with implications that extend beyond New York City politics to the study of social- democratic party families more broadly. Drawing on electoral returns, demographic data, campaign materials, and elite interviews, the project demonstrates that …

Development Of The Active Participle Denoting Ongoing Aspect In Heritage Speakers Of Levantine Arabic In The Us, Reem Kanjawi-Faraj

Dissertations, Theses, and Capstone Projects

This study investigated the acquisition, development, and productivity of اسم الفاعل “ism il-fA؟el”, Active Participle (AP) when denoting ongoing aspect in the comprehension and production of heritage speakers (HSs) of Levantine Arabic (LA^[1]).  Ongoing aspect is mainly realized in Arabic by an inflected imperfective verb preceded by a progressive particle (PROG.V) and in certain cases b AP. Our study is comprised of four sub-studies: a Syrian Levantine Arabic (SLA) adult corpus analysis (production of PROG.V and AP/ CACeC template); a cross-sectional LA child heritage comprehension and production experiment (PROG.V and AP/ CACeC template) ; a longitudinal study of …