Digital Commons Network^™

Brief Report: Substance Use Care Continuum In Women With And Without Hiv In The Southern United States, Aditi Ramakrishnan, Ayako W. Fujita, C. Christina Mehta, Tracey E. Wilson, Steve Shoptaw, Adam Carrico, Adaora A. Adimora, Ellen F. Eaton, Deborah L. Jones, Aruna Chandran, Anandi N. Sheth

2020-Current year OA Pubs

BACKGROUND: Substance use (SU) contributes to poor outcomes among persons living with HIV. Women living with HIV (WWH) in the United States are disproportionately affected in the South, and examining SU patterns, treatment, and HIV outcomes in this population is integral to addressing HIV and SU disparities.

METHODS: WWH and comparable women without HIV (WWOH) who enrolled 2013-2015 in the Women's Interagency HIV Study Southern sites (Atlanta, Birmingham/Jackson, Chapel Hill, and Miami) and reported SU (self-reported nonmedical use of drugs) in the past year were included. SU and treatment were described annually from enrollment to the end of follow-up. HIV …

Nurses' Input On The Nursing Shortage, Patty Harnois-Church, Leann Horsley, Kathryn Wilhoit, Holly Wei

Epsilon Sigma at-Large Research Conference

Nurses’ Input on the Nursing Shortage

Purpose: The purpose of this study was to investigate the views of nurses regarding the nursing shortage in Tennessee.

Aim: To achieve this aim, four focus areas were examined through listening sessions with stakeholders across four regions in the state. These focus areas included addressing the nursing pipeline, developing innovative clinical and academic models, supporting nurses' well-being, and sharing data about the shortage of nurses throughout the state.

Methods: A qualitative descriptive study was conducted using focus group interviews for data collection. The study employed a SWOT (Strengths, Weaknesses, Opportunities, and Threats) analysis approach …

Regimes For Lender Of Last Resort Assistance To Illiquid Monetary Institutions: Lessons In The Wake Of Credit Suisse, Paul Tucker

Documents

No abstract provided.

Mental Healthcare Differences Between The United States, Costa Rica, And Sweden, Michaela Diehm

Honors Program: Senior Projects (Public)

Countries such as the United States, Costa Rica, and Sweden differ in the ways that they approach treatment of mental health disorders, which is due to the structure of their healthcare as well as the culture, affordability, accessibility, and type of treatment that is available to the people of that country. A literature review did not reveal a comparison of the three countries related to the topic of mental healthcare, nor use of the three selected countries to review their structures to determine the best approach to combating mental disorders before. Costa Rica and Sweden are both countries with universal …

A Structured Curriculum Supporting Biomedical Trainees’ Transition Into Independent Academic Positions And Early Career Success, Mabel Perez-Oquendo, Gabriele Romano, David P Farris, Varsha Gandhi, Ignacio I Wistuba, Robert E Tillman, Ryan Udan, Paolo Mangahas, Rama Soundararajan

Faculty, Staff and Student Publications

The United States government makes a substantial investment in biomedical training programs each year. However, for most trainees, these opportunities do not translate into career progression in academic research pathways. Only about one-fifth of postdoctoral fellows eventually secure a tenure-track faculty position, and even among these candidates, attrition is high. Although a number of factors govern career choices and career longevity, the transition from trainee to faculty is a challenging process and requires knowledge and skills that are not necessarily developed during a traditional university experience. Many postdoctoral fellows receive adequate training in research skills and scientific communication, but new …

More Than Just A Number: Perspectives From Black Male Participants On Community-Based Interventions And Clinical Trials To Address Cardiovascular Health Disparities., Faith E Metlock, Sarah Addison, Alicia Mckoy, Yesol Yang, Aarhea Hope, Joshua J Joseph, Jing Zhang, Amaris Williams, Darrell M Gray, John Gregory, Timiya S Nolan

Ambulatory and Primary Care Articles

BACKGROUND: Black Americans remain significantly underrepresented and understudied in research. Community-based interventions have been increasingly recognized as an effective model for reckoning with clinical trial participation challenges amongst underrepresented groups, yet a paucity of studies implement this approach. The present study sought to gain insight into Black male participants' perception of clinical trials before and after participating in a community-based team lifestyle intervention in the United States.

METHODS: Black Impact, a 24-week community-based lifestyle intervention, applied the American Heart Association's Life's Simple 7 (LS7) framework to assess changes in the cardiovascular health of seventy-four Black male participants partaking in weekly …

We Need A Solid Scientific Basis For Nature-Based Climate Solutions In The United States, Kimberly A. Novick, Trevor F. Keenan, William R L Anderegg, Caroline P. Normile, Benjamin R K Runkle, Emily E. Oldfield, Gyami Shrestha, Margaret E K Evans, Dennis D. Baldocchi, James T. Randerson, Jonathan Sanderman, Margaret S. Torn, Anna T. Trugman, Christopher A. Williams

Geography

Opinion piece mapping the many challenges and variables around nature-based climate solutions (NbCS) in the United States, and the need to pinpoint large-scale strategies that will lead to significant, durable, and measurable net climate cooling. They must do so without simply displacing emissions to other locations.

Overview Of Resolution Under Title Ii Of The Dodd-Frank Act, Federal Deposit Insurance Corporation (Fdic)

Documents

No abstract provided.

Clinical Care For Life's Essential 8 By Medical Specialty In The United States, An Observational Cohort Study., Michael E Johansen, Madeline R Sterling, Jeremy B Sussman

Heart and Vascular Articles

No abstract provided.

Prescription And Dispensation Of Qt-Prolonging Medications In Individuals Receiving Hemodialysis, Virginia Wang, Chin-Hua Lily Wang, Magdalene M Assimon, Patrick H Pun, Wolfgang C Winkelmayer, Jennifer E Flythe

Faculty, Staff and Students Publications

IMPORTANCE: Individuals with dialysis-dependent kidney failure have numerous risk factors for medication-related adverse events, including receipt of care by multiple clinicians and initiation of some QT-prolonging medications with known risk of torsades de pointes (TdP), which is associated with higher risk of sudden cardiac death. Little is known about the prescription and dispensation patterns of QT-prolonging medications among people receiving dialysis, hindering efforts to reduce drug-related harm from these and other medications in this high-risk population.

OBJECTIVE: To examine prescription and dispensation patterns of QT-prolonging medications with known TdP risk and selected interacting medications prescribed to individuals receiving hemodialysis.

DESIGN, …

Pre-Covid-19 Hospital Quality And Hospital Response To Covid-19: Examining Associations Between Risk-Adjusted Mortality For Patients Hospitalised With Covid-19 And Pre-Covid-19 Hospital Quality, Doris Peter, Shu-Xia Li, Yongfei Wang, Jing Zhang, Jacqueline Grady, Kerry Mcdowell, Erica Norton, Zhenqiu Lin, Susannah Bernheim, Arjun K Venkatesh, Lee A Fleisher, Michelle Schreiber, Lisa G Suter, Elizabeth W Triche

Faculty, Staff and Student Publications

OBJECTIVES: The extent to which care quality influenced outcomes for patients hospitalised with COVID-19 is unknown. Our objective was to determine if prepandemic hospital quality is associated with mortality among Medicare patients hospitalised with COVID-19.

DESIGN: This is a retrospective observational study. We calculated hospital-level risk-standardised in-hospital and 30-day mortality rates (risk-standardised mortality rates, RSMRs) for patients hospitalised with COVID-19, and correlation coefficients between RSMRs and pre-COVID-19 hospital quality, overall and stratified by hospital characteristics.

SETTING: Short-term acute care hospitals and critical access hospitals in the USA.

PARTICIPANTS: Hospitalised Medicare beneficiaries (Fee-For-Service and Medicare Advantage) age 65 and older hospitalised …

A Method To The Madness Iraqi Strategy And Diplomacy In The Persian Gulfwar, James D. Smith

The Thetean: A Student Journal for Scholarly Historical Writing

Most Americans are familiar with the essentials of the Persian Gulf War: Iraq invaded Kuwait, triggering a massive buildup of American troops in Saudi Arabia. These troops eventually invaded Kuwait and drove out the Iraqis, who fled in terror before the American juggernaut. Beyond this, few Americans know much. The war is, perhaps, too recent to have developed the wide interest that currently exists in older conflicts such as the Civil War or World War II; the textbook-worthy strategies employed by General Norman Schwartzkopf's forces therefore go largely unnoticed by the public at large.

A Representative Clinical Course Of Progression, With Molecular Insights, Of Hormone Receptor-Positive, Her2-Negative Bone Metastatic Breast Cancer, Elizabeth Magno, Karen M. Bussard

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Despite treatment advances, breast cancer remains a leading cause of death of women in the United States, mostly due to metastatic disease. Bone is a preferential site for breast cancer metastasis, and most metastatic breast cancer patients experience bone involvement at the time of death. The majority of patients with bone metastatic breast cancer are first diagnosed with and treated for early-stage disease, and from development of early-stage breast cancer to the recurrence of cancer in the bones, up to 30 years may elapse. Throughout this timeframe, a typical patient undergoes many treatments that have effects on the bone microenvironment. …

Federal Home Loan Banks: Actions Related To The Spring 2023 Bank Failures, United States: Governmant Accountability Office (Gao)

Documents

No abstract provided.

One Year Later: Lessons Learned From The March 2023 Bank Failures, Brookings Hutchins Center On Fiscal & Monetary Policy

Documents

No abstract provided.

Reports Of Covid-19 Vaccine Adverse Events In Predominantly Republican Vs Democratic States, David A Asch, Chongliang Luo, Yong Chen

2020-Current year OA Pubs

IMPORTANCE: Antivaccine sentiment is increasingly associated with conservative political positions. Republican-inclined states exhibit lower COVID-19 vaccination rates, but the association between political inclination and reported vaccine adverse events (AEs) is unexplored.

OBJECTIVE: To assess whether there is an association between state political inclination and the reporting rates of COVID-19 vaccine AEs.

DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study used the AE reports after COVID-19 vaccination from the Vaccine Adverse Event Reporting System (VAERS) database from 2020 to 2022, with reports after influenza vaccines from 2019 to 2022 used as a reference. These reports were examined against state-level percentage of Republican …

Apotheosis Of The State And The Decline Of Civilization: A Systems Approach, Robert Bedeski

Comparative Civilizations Review

Humanity is undergoing a second Axial Age. The first, as described by Karl Jaspers, brought transcendence into the vision and self-understanding of humans and the world. The rise of secularism and “Death of God” is dissolving and fragmenting that transcendence — a vital subsystem of the civilization system. Economy, knowledge and government comprise three additional subsystems and have coalesced to form the modern sovereign state, diminishing the traditional place of religion, art and philosophy in civilizations. An example of a state lacking common institutions of transcendence was the Mongol empire. Ruling Russia for a quarter millennium, its state form was …

The Unknown Drug Dealers In The Nhl: Nhl Players, Drug Addiction, And The Need For Regulation Of Prescriptive Drug Use In The Nhl, Keith O'Brien

Hofstra Law Review

The article examines the pervasive issue of painkiller addiction among NHL (National Hockey League) players, which is exacerbated by a league culture that valorizes playing through injuries. It highlights the shortcomings of the current Collective Bargaining Agreement (CBA) in managing and regulating prescription drug use, alongside the inadequate oversight and accountability from the NHL and regulatory bodies like OSHA (Occupational Safety & Health Administration).

From Compromise To Confrontation: The American Secretary Of State James F. Byrnes And His Attempts To Mitigate Disagreements With The Soviet Union As The Cold War Began, John Karl

Comparative Civilizations Review

James F. Byrnes as United States Secretary of State pursued a policy based on compromise with the Soviet Union during the first year following the end of the Second World War. He was determined to use his political skill for engineering compromise in order to bring about an agreement with the Soviet Union which would lead to an era of peace. While the crucial question facing American policymakers in the wake of World War II was the creation of a new world order, a most important part of this question was the future of American-Soviet relations, the two nations that …

A Job Satisfaction Evaluation Of Nursing In The United States And Greece Utilizing The American Nurses Association's Scope And Standards Of Practice, Audrey Narhi

Honors Projects

Nursing is a multifaceted profession that is constantly evolving with the health needs of the populations it serves. Professional organizations within the field utilize evidence-based practice to provide guidelines of what best-practice nursing is. This study aims to evaluate if the American Nurse's Association (ANA), a professional nursing organization in the United States, supports the realities of nursing in a rural US hospital. An international perspective is also considered by evaluating the same principles to a urban hospital in Athens, Greece. Categories that align with ANA Scope and Standards, including workplace environment, career development, supervisor relationships, and personal work practice, …

Evaluation Of A Collaborative Model Between Managed Care And Affordable Housing On Acute Care Costs, Jack Tsai, Suja Rajan, Chau Truong, Vanessa Schick, Cecilia Ganduglia Cazaban

Faculty, Staff and Student Publications

Objectives: This study evaluated a collaborative service model between the largest Medicaid managed care organization (MCO) in Texas, Superior HealthPlan, and the affordable housing provider Prospera Housing Community Services.

Study design: Using a quasi-experimental 2-groups research design, we compared health care outcomes and costs between a sample of 104 participants served by the Prospera+Superior collaborative model and a group of 104 participants who had health care coverage through the Superior HealthPlan Medicaid MCO but did not live at Prospera properties (ie, Superior-only group).

Methods: Data from medical claims were analyzed to examine change in outcomes 12 months before and after …

Association Between Medication Adherence And Asthma Among Latinos In The United States, Denisse Silva

Walden Dissertations and Doctoral Studies

Prior research has shown that Latinos in the United States face disproportionate challenges in managing their asthma symptoms. Therefore, this study aimed to identify factors that may influence medication adherence and asthma episodes among Latinos in the United States and was guided by Andersen’s health behavior theory. Data from 2020 Latinos who participated in the National Health Interview System in 2020 were analyzed. Findings indicated that nearly 23% of respondents reported an asthma episode. Approximately 25% of the sample reported an asthma episode during the last 12 months. A total of 43.6% of the sample reported not taking medication every …

Obstetric Racism, Education, And Racial Concordance, Terri L Major-Kincade

Faculty, Staff and Student Publications

The United States holds the distinction of being the developed country with the worst perinatal outcomes despite spending the most per capita on health care. Black women are three to four times more likely than White women to experience adverse birth outcomes. These outcomes persist despite access to prenatal care, insurance, and college education. A long overdue racial reckoning has arrived, beginning with acknowledging the fallacy of race-based medicine and the role of enduring systemic racism as foundational to obstetric racism in the reproductive lives of Black women. Centering voices of Black women and honoring their lived experiences are essential …

Examining Full-Time Academic General Pediatric Faculty Compensation By Gender, Race, And Ethnicity: 2020-2021, Emma A Omoruyi, Callie L Brown, Colin J Orr, Kimberly Montez

Faculty, Staff and Student Publications

Objective: In medicine, women have lower lifetime earnings than men. To our knowledge, an in-depth examination of academic general pediatric faculty compensation by gender, race, and ethnicity has not been conducted. We aimed to 1) explore full-time academic general pediatric faculty salary differences by race and ethnicity; 2) explore these differences among all full-time pediatric faculty.

Methods: We performed a cross-sectional study using data on median full-time academic general pediatric faculty compensation for the academic year of 2020-2021 from the Association of American Medical Colleges Medical School Faculty Salary Survey report. Pearson's chi-square tests were used to evaluate the association …

The Frequency Of Pathogenic Variation In The All Of Us Cohort Reveals Ancestry-Driven Disparities, Eric Venner, Karynne Patterson, Divya Kalra, Marsha M Wheeler, Yi-Ju Chen, Sara E Kalla, Bo Yuan, Jason H Karnes, Kimberly Walker, Joshua D Smith, Sean Mcgee, Aparna Radhakrishnan, Andrew Haddad, Philip E Empey, Qiaoyan Wang, Lee Lichtenstein, Diana Toledo, Gail Jarvik, Anjene Musick, Richard A Gibbs

Faculty, Staff and Students Publications

Disparities in data underlying clinical genomic interpretation is an acknowledged problem, but there is a paucity of data demonstrating it. The All of Us Research Program is collecting data including whole-genome sequences, health records, and surveys for at least a million participants with diverse ancestry and access to healthcare, representing one of the largest biomedical research repositories of its kind. Here, we examine pathogenic and likely pathogenic variants that were identified in the All of Us cohort. The European ancestry subgroup showed the highest overall rate of pathogenic variation, with 2.26% of participants having a pathogenic variant. Other ancestry groups …

Generalizable Pipeline For Constructing Hiv Risk Prediction Models Across Electronic Health Record Systems, Sarah B May, Thomas P Giordano, Assaf Gottlieb

Faculty, Staff and Student Publications

OBJECTIVE: The HIV epidemic remains a significant public health issue in the United States. HIV risk prediction models could be beneficial for reducing HIV transmission by helping clinicians identify patients at high risk for infection and refer them for testing. This would facilitate initiation on treatment for those unaware of their status and pre-exposure prophylaxis for those uninfected but at high risk. Existing HIV risk prediction algorithms rely on manual construction of features and are limited in their application across diverse electronic health record systems. Furthermore, the accuracy of these models in predicting HIV in females has thus far been …

Association Between Sociodemographic Variables And Low Birthweight Among Disabled Black Mothers, Yewunetu Dessalegn Malefia

Walden Dissertations and Doctoral Studies

Low birthweight (LBW) affects around 30 million infants annually. Infants with LBW face a 20-fold risk of mortality compared to those weighing 2,500 grams or more at birth. In the United States, the prevalence of LBW is nearly double among Blacks compared to Whites. Despite 61 million U.S. adults with disabilities, including 35 million women, there remains a significant research gap concerning factors that contribute to LBW among Black mothers with a disability (BMWD). This retrospective study employed 2019 and 2020 Pregnancy Risk Assessment Monitoring System (PRAMS) datasets to investigate the association between LBW and sociodemographic factors among BMWD. Bivariate …

Pulmonary Fibrosis Stakeholder Summit: A Joint Nhlbi, Three Lakes Foundation, And Pulmonary Fibrosis Foundation Workshop Report, Sydney B Montesi, Christian R Gomez, Michael Beers, Robert Brown, Ishanu Chattopadhyay, Kevin R Flaherty, Christine Kim Garcia, Brigitte Gomperts, Lida P Hariri, Cory M Hogaboam, R Gisli Jenkins, Naftali Kaminski, Grace Hyun J Kim, Melanie Königshoff, Martin Kolb, Darrell N Kotton, Jonathan A Kropski, Joseph Lasky, Chelsea M Magin, Toby M Maher, Mark Mccormick, Bethany B Moore, Cheryl Nickerson-Nutter, Justin Oldham, Anna J Podolanczuk, Ganesh Raghu, Ivan Rosas, Steven M Rowe, William T Schmidt, David Schwartz, Jessica E Shore, Cathie Spino, J Matthew Craig, Fernando J Martinez

Faculty, Staff and Students Publications

Despite progress in elucidation of disease mechanisms, identification of risk factors, biomarker discovery, and the approval of two medications to slow lung function decline in idiopathic pulmonary fibrosis and one medication to slow lung function decline in progressive pulmonary fibrosis, pulmonary fibrosis remains a disease with a high morbidity and mortality. In recognition of the need to catalyze ongoing advances and collaboration in the field of pulmonary fibrosis, the NHLBI, the Three Lakes Foundation, and the Pulmonary Fibrosis Foundation hosted the Pulmonary Fibrosis Stakeholder Summit on November 8–9, 2022. This workshop was held virtually and was organized into three topic …

The Intersection Of Monetary Policy, Market Functioning, And Liquidity Risk Management, Michael S. Barr

Documents

No abstract provided.

Universal Risk Prediction For Individuals With And Without Atherosclerotic Cardiovascular Disease, Yejin Mok, Zeina Dardari, Yingying Sang, Xiao Hu, Michael P Bancks, Lena Mathews, Ron C Hoogeveen, Silvia Koton, Michael J Blaha, Wendy S Post, Christie M Ballantyne, Josef Coresh, Wayne Rosamond, Kunihiro Matsushita

Faculty, Staff and Students Publications

Background: American College of Cardiology/American Heart Association guidelines recommend distinct risk classification systems for primary and secondary cardiovascular disease prevention. However, both systems rely on similar predictors (eg, age and diabetes), indicating the possibility of a universal risk prediction approach for major adverse cardiovascular events (MACEs).

Objectives: The authors examined the performance of predictors in persons with and without atherosclerotic cardiovascular disease (ASCVD) and developed and validated a universal risk prediction model.

Methods: Among 9,138 ARIC (Atherosclerosis Risk In Communities) participants with (n = 609) and without (n = 8,529) ASCVD at baseline (1996-1998), we examined established predictors in the …