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Dissecting The Molecular Mechanism Of Early Tumor Dissemination In Non-Small Cell Lung Cancer, Xingtong Liu Jun 2018

Dissecting The Molecular Mechanism Of Early Tumor Dissemination In Non-Small Cell Lung Cancer, Xingtong Liu

Dissertations and Theses (Open Access)

Lung cancer is the most common cause of cancer related death in the United States and worldwide. It has been shown that 30%-55% of patients with early stages of non-small cell lung cancer (NSCLC) developed and died of recurrence after curative resection, suggesting that tumor cell dissemination occurred early in those patients before surgery. However, molecular evidence, underline mechanisms and risk factors for the NSCLC relapse remain largely unknown. Addressing these questions will be critical for the development of strategies to stratify the risk of recurrence and approaches to reduce these risks. My thesis focused on dissecting the molecular basis …


Music As A Social Determinant Of Health: A Trauma-Informed Care Perspective, Nomi Levy-Carrick, Abi Warren Jun 2018

Music As A Social Determinant Of Health: A Trauma-Informed Care Perspective, Nomi Levy-Carrick, Abi Warren

Crossroads of Music and Medicine

Traumas can be individual, interpersonal or communal, and can have various responses from different people, or even from the same person at different points in time. Music can be a social determinant of health with individual, interpersonal and communal roles in resilience regarding that trauma. Music can expand vocabulary to express emotions, provide relief, and provide opportunities for engagement. A trauma-informed care approach can change how trauma survivors experience care critical to their recovery.


Nativity Differences In Stress Among Asian And Pacific Islander American Women, Brittany N. Morey, Gilbert C. Gee, Salma Shariff-Marco, Gem M. Le, Alison J. Canchola, Juan Yang, Laura Allen, Sandra Lee, Roxanna Bautista, Trish Quema La Chica, Winston Tseng, Pancho Chang, Scarlett Lin Gomez May 2018

Nativity Differences In Stress Among Asian And Pacific Islander American Women, Brittany N. Morey, Gilbert C. Gee, Salma Shariff-Marco, Gem M. Le, Alison J. Canchola, Juan Yang, Laura Allen, Sandra Lee, Roxanna Bautista, Trish Quema La Chica, Winston Tseng, Pancho Chang, Scarlett Lin Gomez

Journal of Health Disparities Research and Practice

According to the Stress Process Theory, people who are marginalized in society encounter more stress than those in more advantaged positions. Immigrants are one such marginalized group in the United States (US) who may experience greater psychological stress than their US-born counterparts due to (1) severing of social ties; (2) social disadvantage and marginalization; and (3) adaptation to a new environment. This study examines the disparity in stress by nativity, and how social factors contribute to this disparity for Asian and Pacific Islander (API) women. Data come from the Asian Community Health Initiative, which included a sample of 291 foreign-born …


The Relationship Between Loneliness, Stress, And Alcohol Consumption Among College Students, I'Esha Baber May 2018

The Relationship Between Loneliness, Stress, And Alcohol Consumption Among College Students, I'Esha Baber

Electronic Theses and Dissertations

As the misuse of alcohol among college students remains a public health concern in the United States, students are participating in problematic drinking for various reasons. Loneliness and stress have both been associated with the reasoning behind why some college students participate in heavy drinking. Studies show that students who perceive themselves as under a lot of stress tend to drink more and that students who feel they need to overcome structural and emotional barriers such as loneliness and shyness, use alcohol as a resource. This paper examines the relationship between alcohol consumption, loneliness, and stress. Sixteen students, who attended …


Real-Time Detection Of Cravings In Individuals With Substance Abuse Using Wearable Biosensors And Machine Learning, Keerthi Kumar Chintha May 2018

Real-Time Detection Of Cravings In Individuals With Substance Abuse Using Wearable Biosensors And Machine Learning, Keerthi Kumar Chintha

Electrical Engineering Theses

Deaths in the US have drastically increased over the past decade due to addictive behaviors and drugs. According to the World Health Organization (WHO), 1 in 20 adults between the age of 15 and 64 years are addicted to at least one illicit drug; globally, 29 million people are suffering from drug use disorder. The addiction of narcotics alters a person’s primary function as well as critical areas of the brain due to multiple reasons like genetics, hereditary, stress or pressure, and mental health conditions. It not only affects an individual but also their families. Intensive research has been launched …


Parental Mindfulness And Stress As An Influence On Clinically Referred Children’S Emotional Competence, Ahmad Baiyasi May 2018

Parental Mindfulness And Stress As An Influence On Clinically Referred Children’S Emotional Competence, Ahmad Baiyasi

Honors College Theses

Children acquire the skills of emotional competence in a variety of contexts, and demonstrate through their behavior the skills evident of emotional competence. Such skills include a sense of well-being, adaptive resilience in the face of stressful circumstances, and the ability to manage their own emotions (Saarni, 2000). Mindfulness, a relatively new construct in the study of human development, is nonjudgmentally paying attention to relevant aspects of our experiences, including our own emotions and thoughts (Ludwig & Kabat-Zinn, 2008). Stress is emotional or mental strain resulting from adverse or very demanding life circumstances, such as our living environment (Lunney, 2006). …


Stress Management And The Novice Nurse, Patrice Lawrency May 2018

Stress Management And The Novice Nurse, Patrice Lawrency

Nursing Theses and Capstone Projects

The stress of the novice nurse impacts the quality of patient care, emotional, and physical wellbeing of the novice nurse and hospital costs. The aging of the Baby Boomer generation is impacting the nursing profession. These factors should be addressed to promote the retention of novice nurses in the profession. Research has shown that the mitigation of stress in the novice nurse can have a positive impact on the nursing shortage. An inundation of literature exists on the evolution process from the academic to the clinical setting, but few studies identified resources to provide support to the novice nurse. Strategies …


Differential Impact Of Psychological And Physiological Health Outcomes On Long-Term Associative Recognition, James D. Schaeffer May 2018

Differential Impact Of Psychological And Physiological Health Outcomes On Long-Term Associative Recognition, James D. Schaeffer

Psychology Dissertations - Archive

Evidence suggests that lifestyle and environmental factors may contribute to later life cognitive decline and dementia. Although there is a large amount of evidence linking psychological and physiological factors to general memory performance, little focus has been given to specific memory systems. The present study was designed to investigate relationships between psychophysiological health predictors and recollection and familiarity processes of recognition memory. We hypothesized that these recognition processes may be differentially impacted by the included health variables. The present study involved 96 relatively healthy young adults between 17 and 25 years old. Health measures included visceral obesity (waist-to-hip ratio), heart …


Levels Of Professional Stress In Missouri State University Sport Coaches, James Edgar Seratt May 2018

Levels Of Professional Stress In Missouri State University Sport Coaches, James Edgar Seratt

Graduate Theses/Dissertations

Due to the particular nature of collegiate sport coaching, that is, the need to secure victories at all costs in order to ensure job security, collegiate sport coaches are a population that are likely to experience high levels of personal and professional stress. Previous research has indicated that coaches at all levels of competition, experience degrees and levels of stress similar to those experienced by individuals in other high stress professions, including police officers, medical professionals, and teachers. Furthermore, research has indicated that high levels of stress are positively correlated with decreased work performance. For this research, 45 Missouri State …


Nuns Making Fun: An Exploration Of Humor Among Women Religious, Megan Lyn Routh May 2018

Nuns Making Fun: An Exploration Of Humor Among Women Religious, Megan Lyn Routh

Sociology & Anthropology Theses - Archive

This paper discusses the role and use of humor in the lives of nuns and consecrated women. A qualitative study consisting of interviews with nuns and consecrated women was conducted to produce data about the way in which they use humor. Humor among these women was examined through the framework of identity and social identity theories, as well as front and back stage presentation, and theories of humor as a method of emotion management for coping with stress. Results show that Catholic and women religious social identities influence the women’s perspective of humor as a positive force and a method …


Three Speeds Of Yoga And The Effects On Salivary Cortisol Levels In Female Nursing Students, Meagan Hennekens May 2018

Three Speeds Of Yoga And The Effects On Salivary Cortisol Levels In Female Nursing Students, Meagan Hennekens

All NMU Master's Theses

Purpose: Nursing students are prone to stress-related diseases, such as depression and anxiety, which are associated with chronically elevated cortisol levels due to the excessive firing of the Hypothalamic Pituitary Adrenal (HPA) axis. This study assessed three speeds of yoga and how they acutely affected salivary cortisol levels within female nursing students. Methods: Students participated in three yoga sessions cadenced at different speeds in a non-randomized order: (i) standard-speed yoga (SSY), (ii) high-speed yoga (HSY), and (iii) slow-speed yoga (SLSY). Each class integrated sequencing concepts from the brahmana/langhana strategy (BLS) and the Para Yoga Blueprint (PYB). Cortisol samples were …


Gendered Responses To Stress: Differences Across Type Of Stressor And Mental Health Outcomes, Erin Voichoski May 2018

Gendered Responses To Stress: Differences Across Type Of Stressor And Mental Health Outcomes, Erin Voichoski

Honors Program: Senior Projects (Public)

It is well known in mental health literature that men and women tend to manifest distinct mental health outcomes. Specifically, women tend to report higher levels of internalizing symptoms, such as depression and anxiety, whereas men tend to report higher levels of externalizing symptoms, such as alcohol abuse and antisocial behavior. This research will further explore the relationship between stress and mental health, as well as the moderating effect of gender. Drawing from the differential vulnerability hypothesis and self-salience theory, I take a novel approach to examining a variety of stressors and mental health outcomes. I assess whether stressors that …


Sociality And Stress In Female Chacma Baboons (Papio Ursinus) In The Cape Peninsula Of South Africa: Behavioral Flexibility And Coping Mechanisms, Shahrina Chowdhury May 2018

Sociality And Stress In Female Chacma Baboons (Papio Ursinus) In The Cape Peninsula Of South Africa: Behavioral Flexibility And Coping Mechanisms, Shahrina Chowdhury

Dissertations, Theses, and Capstone Projects

The physiological stress responses that animals exhibit to the myriad stressors in their environment can be used to assess the state of their health and well-being, and even survival capability. Although the stress response is adaptive in many cases, chronic stress responses may be maladaptive in some situations when it leads to dysfunction of the physiological system involved in the stress response itself, and can also cause deleterious effects on health, reproduction and survival. The stress response includes physiological responses to both environmental perturbations and psychosocial stress and anxiety associated with social perturbations. The latter factor is particularly important for …


The Moderating Effects Of College Stress On The Relationship Protective Behavioral Strategies Has With Hazardous Alcohol Consumption And Negative Consequences, Bobbi Lynn Lee May 2018

The Moderating Effects Of College Stress On The Relationship Protective Behavioral Strategies Has With Hazardous Alcohol Consumption And Negative Consequences, Bobbi Lynn Lee

Honors Theses

Hazardous drinking continues to be a problem on college campuses especially when considering the increased negative consequences often associated with use at these levels. Although alcohol use is viewed as normative behavior among college students, many factors may predict increased or decreased use and negative consequences. Protective behavioral strategies (PBS) are related to decreased hazardous drinking and alcohol-related negative consequences. Specifically, controlled consumption PBS (PBS-CC) are related to less hazardous drinking while serious harm reduction PBS (PBS-SHR) are often related to fewer alcohol-related negative consequences. Stress is also linked with hazardous drinking as students may drink to cope with this …


Positive Experiences As Countermeasures To Stress In Spaceflight: An Investigation Of The Experiences Of Astronauts, Morgan M. Eudy May 2018

Positive Experiences As Countermeasures To Stress In Spaceflight: An Investigation Of The Experiences Of Astronauts, Morgan M. Eudy

Theses and Dissertations

Long-duration space mission targets such as asteroids, the Moon and Mars in coming years will increase the need to stress management techniques to support crews on increasingly risky, autonomous missions. New stress management approaches may be found by better understanding the reported positive effects resulting from factors in these environments. This study utilized an exploratory case study approach to leverage quantitative and qualitative data to yield research questions for future correlational analysis. This study found that positive experiences and changes in environmental perspectives occurred from viewing Earth from orbit. Furthermore, this study found that personality factors such as extraversion may …


Nurses' Health And Professional Quality Of Life, Deborah Amason Apr 2018

Nurses' Health And Professional Quality Of Life, Deborah Amason

Doctor of Nursing Practice (DNP) Translational and Clinical Research Projects

Nurse's Health and Professional Quality of Life

Abstract

This study investigated relationships between general health (GH), professional quality of life (PQL) and perceived stress (PS) of nurses at a 382-bed southeastern hospital.

Background: Several studies showed that GH and PQL are associated. The health, quality of life, and perceived stress of nurses was a growing concern in the hospital. Nurse leaders needed data to inform evidence-based efforts to promote nurse health and improve quality of life while reducing stress.

Design: This cross-sectional correlation study measured GH, PQL, and PS using four validated and reliable instruments: The Medical Outcomes Short Form …


Stress, Anxiety And Depression In Students Of A Private Medical School In Karachi, Pakistan, Noman Rehmani, Qurat Ul Ain Khan, Syeda Sadia Fatima Apr 2018

Stress, Anxiety And Depression In Students Of A Private Medical School In Karachi, Pakistan, Noman Rehmani, Qurat Ul Ain Khan, Syeda Sadia Fatima

Department of Psychiatry

Objective: To determine frequency of stress, anxiety and depression and their coping mechanisms in undergraduate students of a private sector university.

Methods: A cross sectional study was conducted at Aga Khan University recruiting students from Medical School, School of Nursing & Midwifery, and Dental Hygiene program who had attended at least six months on campus from October 2016 until August 2017. The “Aga Khan University Anxiety and Depression Scale” and “Student-Life Stress Inventory” scales were used to assess depression and anxiety, and stressors.

Results: A total of 283 students participated in this study and all of them scored higher than …


Photonic Probing Of Structural Deformation Of Brain Tissues Due To Stress And Alcohol, Shiva Bhandari Apr 2018

Photonic Probing Of Structural Deformation Of Brain Tissues Due To Stress And Alcohol, Shiva Bhandari

Electronic Theses and Dissertations Archive

Mesoscopic optical physics based Partial Wave Spectroscopy(PWS) and Inverse Participation Ratio(IPR) techniques are sensitive to nanoscale and submicron-scale changes respectively occurring in the biological cells. These changes occur due to several factors; stress and fetal alcoholism are deemed to be the major ones. The effects of chronic stress in adult brain cells and fetal alcoholism on the brain cells of fetus are studied using the respective animal models. PWS studies the effect of stress in brain tissues by measuring the optical backscattering spectra and quantifying the statistical properties of the nano-architecture of the tissues by the analysis of the fluctuating …


Mindfulness As A Vigilance Intervention: Examining Its Impact On Stress And Mental Demand, Kelli Huber Apr 2018

Mindfulness As A Vigilance Intervention: Examining Its Impact On Stress And Mental Demand, Kelli Huber

Dissertations

Occupations involving vigilance performance (i.e., sustained attention in monitoring for rare environmental threats) are known to experience vigilance decrement, a decline in performance over time. These occupations are known to be cognitively and emotionally challenging, giving rise to harmful effects for employees in them and presenting safety implications for the welfare of others. The current study investigated mindfulness as a potentially viable intervention to alleviate outcomes of vigilance demands: stress and mental demand. A mindfulness induction was compared to an unfocused control condition in which both were administered during a break from a vigilance task, specifically, a baggage screening task. …


"I Never Expected This": Expectancy Violations And Stress In Millennials, Sarah Pogue Apr 2018

"I Never Expected This": Expectancy Violations And Stress In Millennials, Sarah Pogue

Honors Program: Senior Projects (Public)

Millennials are said to be the most stressed out age group in the United States (Coccia, & Darling, 2016). Between general life stressors and the new stress that has emerged due to the increase in technology and social communication, millennials are simply overloaded with stress from all angles. In order to communicate and make sense of this stress, most millennials find themselves discussing these stressful events with their close friends. In fact, according to Jody Koenig Kellas, Haley Kranstuber Horstman, Erin K. Willer, and Kirsten Car (2015), 95% of people tell stories about stressful events soon after they occur to …


Self-Compassion And Adherence In Five Medical Samples: The Role Of Stress, Fuschia M. Sirois, Jameson K. Hirsch Apr 2018

Self-Compassion And Adherence In Five Medical Samples: The Role Of Stress, Fuschia M. Sirois, Jameson K. Hirsch

ETSU Faculty Works

Emerging evidence indicates self-compassion can be beneficial for medical populations and for medical adherence; yet, research to date has not fully examined the reasons for this association. This study examined the association of dispositional self-compassion to adherence across five medical samples and tested the extent to which perceived stress accounted for this association. Five medical samples (total N = 709), including fibromyalgia, chronic fatigue syndrome, and cancer patients, recruited from various sources, completed online surveys. Self-compassion was positively associated with adherence in all five samples. A meta-analysis of the associations revealed a small average effect size (average r = .22, …


Employees’ Financial Insecurity And Health: The Underlying Role Of Stress And Work–Family Conflict Appraisals, Heather N. Odle-Dusseau, Russell A. Matthews, Julie H. Wayne Apr 2018

Employees’ Financial Insecurity And Health: The Underlying Role Of Stress And Work–Family Conflict Appraisals, Heather N. Odle-Dusseau, Russell A. Matthews, Julie H. Wayne

Management Faculty Publications

Data from two longitudinal samples were utilized to elucidate underlying mechanisms of the well‐established relationship between financial insecurity and health outcomes, stemming from the theoretical rationale of conservation of resources and cognitive appraisal theories. Study 1 (n = 80) consisted of low‐wage food manufacturing employees working full time, while Study 2 (n = 331) was consisted of a larger, heterogeneous sample of full‐time workers representing multiple occupations. Respondents were surveyed on financial insecurity, work‐to‐family conflict (WFC), stress, and health outcomes at two time periods, 3 months apart. Results across our studies provided support for the direct effects of …


The Impact Of Mindfulness Practices On Classroom Climate And Perceived Teacher Stress, Erin Kathryn Hebert Apr 2018

The Impact Of Mindfulness Practices On Classroom Climate And Perceived Teacher Stress, Erin Kathryn Hebert

LSU Master's Theses

BACKGROUND: Teaching has been identified as the most stressful profession in the human service industry (Greenberg, Brown, & Abenavoli, 2016). Elevated teacher stress can affect teacher well-being and burnout, as well as, classroom climate and student outcomes. OBJECTIVE: The purpose of this research study was to assess whether mindfulness practices can increase positive classroom climate and decrease perceived stress in early childhood teachers. METHOD: Participating teachers were selected based on results of the Perceived Stress Scale (PSS; Cohen, Kamarck, & Mermelstein, 1983). Data were collected on the positive and negative climate objectives from the Classroom Assessment Scoring System …


Cerebrovascular Dysfunction With Stress And Depression, Emily Burrage, Kent L. Marshall, Nalini Santanam, Paul D. Chantler Apr 2018

Cerebrovascular Dysfunction With Stress And Depression, Emily Burrage, Kent L. Marshall, Nalini Santanam, Paul D. Chantler

Clinical and Translational Science Institute

Maintenance of adequate tissue perfusion through a dense network of cerebral microvessels is critical for the perseveration of normal brain function. Regulation of the cerebral blood flow has to ensure adequate delivery of nutrients and oxygen with moment-to-moment adjustments to avoid both hypo- and hyper-perfusion of the brain tissue. Even mild impairments of cerebral blood flow regulation can have significant implications on brain function. Evidence suggests that chronic stress and depression elicits multifaceted functional impairments to the cerebral microcirculation, which plays a critical role in brain health and the pathogenesis of stress-related cognitive impairment and cerebrovascular events. Identifying the functional …


Tipsheet: Student Mental Health And Resources, Unl Office Of The Executive Vice Chancellor Apr 2018

Tipsheet: Student Mental Health And Resources, Unl Office Of The Executive Vice Chancellor

United States Public Health Resources

Stress, depression, anxiety, alcohol abuse, eating disorders, and other mental health challenges affect at least 1 in 5 college students*. Faculty can be an important source of support for UNL students. Here are some strategies for supporting student mental health:

1. Communicate the importance of mental health. Mental health is just as important as physical health. When someone breaks a leg they go to the hospital. Mental illness is the same thing. If someone is feeling depressed they should seek treatment. Normalize mental health by talking about getting support if you notice your students struggling with stress, depression, anxiety, etc. …


Self-Efficacy As A Predictor Of Stress In Medical Students Of King Khalid University, Saudi Arabia, Aesha F. Siddiqui Apr 2018

Self-Efficacy As A Predictor Of Stress In Medical Students Of King Khalid University, Saudi Arabia, Aesha F. Siddiqui

Makara Journal of Health Research

Background: Self-efficacy and stress are closely related concepts. These concepts have been endorsed as the primary causes influencing the adaptation of students to the college environment. The objectives of this study were to: 1) Measure self-efficacy among medical students, 2) Study association of self-efficacy with basic characteristics of the students, 3) Determine the role of self-efficacy as a predictor of stress. Methods: Self efficacy and stress were measured using the Kesseler-10 instrument and the General Self Efficacy scale, for 267 medical students, including both sexes. Statistical analysis included descriptive statistics for the basic characteristics and self-efficacy, independent samples t-test and …


An Exploration Of The Effects Of Parenting A Child Diagnosed With Autism Spectrum Disorder, Morgan Wherry Apr 2018

An Exploration Of The Effects Of Parenting A Child Diagnosed With Autism Spectrum Disorder, Morgan Wherry

Honors Theses

There is an increasing prevalence of ASD diagnoses, which calls for more research on the caregivers. This study’s goal was to explore primary and secondary sources to identify themes of potential research within this topic. This study analyzed the existing literature and archival data to create seven themes: parental stress, stress-inducing ASD symptomology, ASD vs. other disorders, mothers vs. fathers, coping mechanisms of caregivers, substance use, and incarceration. A potential future research project idea is presented.


Prosocial Behavior As A Stress Moderator: The Physiological And Psychological Components, Jessica Vannelli Apr 2018

Prosocial Behavior As A Stress Moderator: The Physiological And Psychological Components, Jessica Vannelli

Senior Honors Theses

Stress is a major part of everyday life for the majority of people, especially college students. Stress has a physiological response and serves an important purpose in the body. If an individual does not take the proper measures to reduce stress and it continues for long periods of time, the outcome can be damaging to the stressed individual. Stress can cause problems both physically and mentally. There are many different ways to reduce stress and to counteract the damage that stress can cause on the body. Prosocial behavior is an action that elevates others’ needs over an individual’s needs. Studies …


How To Prevent Childhood Obesity, Uyen Lam Apr 2018

How To Prevent Childhood Obesity, Uyen Lam

All Student-Created Educational Resources

This handout explains what causes childhood obesity, the effective solutions, and how to prevent it.


Parenting In The Context Of Deportation Risk, Jodi Berger Cardoso, Jennifer L. Scott, Monica Faulkner, Liza Barros Lane Apr 2018

Parenting In The Context Of Deportation Risk, Jodi Berger Cardoso, Jennifer L. Scott, Monica Faulkner, Liza Barros Lane

Faculty Publications

Nearly 5.1 million children younger than age 18 live with at least one undocumented parent, about 7% of the U.S. child population. Between 2010 and 2013, an estimated 300,000 parents of U.S. citizen children were deported. Raising children in the context of deportation risk increases overall parenting stress for undocumented Latino parents. To investigate this and understand the experience of undocumented parenting, the authors interviewed 70 undocumented parents in two Southwest cities from 2012 to 2013. The authors frame their analysis using the lens of the problem of “illegality.” There are three domains of stressors associated with parenting in the …