Digital Commons Network^™

Sedentary Behavior And Obesity In A Large Cohort Of Children, Jonathan A. Mitchell, Calum Mattocks, Andy R. Ness, Sam D. Leary, Russell R. Pate, Marsha Dowda, Steven N. Blair, Chris Riddoch

Faculty Publications

The purpose of this study was to examine the association between sedentary behavior and obesity among 12-year-old children, while adjusting for moderate-to-vigorous physical activity (MVPA) and other potential confounding variables.

Cross-sectional analyses were carried out with data from 5434 children who participated in the Avon Longitudinal Study of Parents and Children (ALSPAC). Fat mass was derived using dual x-ray emission absorptiometry (DXA), and height and weight measurements were used to calculate body mass index (BMI; kg/m²). The children wore an accelerometer for seven days. The cut points for sedentary behavior and MVPA were ≤199 cpm and ≥3600 cpm, …

The Relationship Between Calcium Intake, Obesity, And Cardiovascular Disease Risk Factors: The Jackson Heart Study, Marjuyua Lartey-Rowser

Dissertations

Cardiovascular disease (CVD) is a major health risk in the United States. Major indicators of CVD risk include obesity, blood lipids, and blood pressure. Modifiable risk factors associated with CVD include body composition (body mass index and waist circumference), serum lipids, and blood pressure. Data suggest calcium intake may play a role in regulation of weight, serum lipids, and blood pressure. The purpose of this study was to assess relationships of dietary calcium intake with weight status, and cardiovascular disease risks in African American population participating in the Jackson Heart Study.

The subjects included 4,267 African American adults ages 21-95 …

The Effects Of Obesity And Surgically-Induced Weight Loss On Exercise Ventilation: Influence Of Central Adiposity And Serum Leptin, Jeffrey Herrick

Theses and Dissertations

Truncal adiposity impairs ventilation in obese adults by altering normal ventilatory mechanics. Leptin, an inflammatory adipocytokine, is elevated in obesity and has been shown to alter ventilatory responses to exercise. Leptin’s bioavailability appears to be regulated by its soluble receptor (LRe), which is reduced in obesity. Roux-en-Y gastric bypass surgery (RYGBS) is a weight loss intervention that reduces total fat mass and improves several obesity related co-morbidities including pulmonary dysfunction. The purpose of this study was to first evaluate the differences between ventilatory responses to carbon dioxide (VE/VCO2 slope) during progressive treadmill walking in morbidly obese and normal weight females. …

Monitoring, Identification, And Intervention For Metabolic Disorders In Veterans With Psychotic Disorders, Michael Swtye

Yale Medicine Thesis Digital Library

In light of growing evidence that certain antipsychotics may cause potentially life-threatening metabolic side-effects, the purpose of this study was to determine how regularly mental health clinicians (MHCs) currently monitor and manage metabolic abnormalities in overweight and obese patients with psychotic disorders. We hypothesized that MHCs monitor, identify and intervene for metabolic abnormalities in their patients at significantly lower rates than primary care physicians (PCCs), and that such rates may jeopardize patient health. We performed a one-year cross-sectional medical record review of primary care and mental health routine outpatient visit notes from the West Haven Campus of the Veteran Affairs …

Number Of Aberrant Crypt Foci Associated With Adiposity And Igf1 Bioavailability, Helen Swede, Joseph C. Anderson, Richard G. Stevens, Joel Levine, Bruce M. Brenner, Carl D. Malchoff, Valerie B. Duffy, Devon C. Pleau, Daniel W. Rosenberg

Articles - Patient Care

Background Dysregulation of the insulin-like growth factor (IGF) system, a common consequence of adiposity-induced insulin resistance, may be a key underlying mechanism linking excess body weight with colon cancer. Evidence has been derived from studies of cancer and polyps. Supporting data about aberrant crypt foci (ACF), putative pre-polyp changes, have been generated only from animal studies to date. Methods We randomly selected 26 patients with sex-specific elevated waist-hip-ratio (WHR) and 26 with normal values from a series of 150 patients seeking routine colonoscopy at the University of Connecticut Health Center. Cross-sectional analyses were performed of ACF number (<5, ≥5) in relation to total IGF1, IGF-binding protein-3 (IGFBP3), insulin, body mass index (BMI), WHR and waist circumference (WC). Visualized ACF in the 20 cm of the distal colon were counted using advanced endoscopic imaging. Results Patients …

Carbohydrate Intake And Overweight And Obesity Among Healthy Adults, Anwar T. Merchant, Hassanali Vatanparast, Shahzaib Barlas, Mahshid Dehghan, Syed Mahboob Ali Shah, Lawrence De Koning, Susan E. Steck

Faculty Publications

Background - Little is known about the dietary habits of people with optimal body weight in communities with high overweight and obesity prevalence.

Objective - To evaluate carbohydrate intake in relation to overweight and obesity in healthy, free-living adults

Design - We used a cross-sectional analysis

Subjects/setting - The Canadian Community Health Survey Cycle 2.2 is a cross-sectional survey of Canadians conducted in 2004-2005. There were 4,451 participants aged 18 years and older with anthropometric and dietary data and no comorbid conditions in this analysis.

Main outcome measures - Outcome variables were body mass index (BMI; calculated as kg/m^{2 …}

Metabolic Syndrome And Risk Of Cancer Mortality In Men, Jason R. Jaggers, Xuemei Sui, Steven P. Hooker, Michael J. Lamonte, Charles E. Matthews, Gregory A. Hand, Steven N. Blair

Faculty and Staff Scholarship

Background—Metabolic syndrome (MetS) has been linked with an increased risk of developing cancer; however the association between MetS and cancer mortality remains less clear. Little research has focused on pre-cancer risk factors that may affect the outcome of treatment. The purpose of this study was to examine the association between MetS and all-cancer mortality in men. Methods—The participants included 33,230 men aged 20-88 years who were enrolled in the Aerobics Center Longitudinal Study and free of known cancer at baseline. Results—At baseline 28% of all the participants had MetS. During an average of 14 years followup there were a total …

Examining An Acute Environmental Trigger For Dysfunctional Eating: Measuring The Immediate Impact Of Fat Disparagement Media Exposure And Its Effects On Body Dissatisfaction, Negative Affect, Weight Control Practice Intentions, And Sub-Clinical Binge Eating Behavior In College Women, Susan Himes

USF Tampa Graduate Theses and Dissertations

Binge eating is a maladaptive eating practice associated with unhealthy weight control methods (vomiting, laxative abuse) and the development of weight gain and obesity. Isolating psychological and environmental variables that trigger binge eating can prevent or potentially moderate eating disturbance. Previous research implicates media exposure as an environmental contributor to psychological and eating disturbance. The current study sought to uncover whether fat stigmatization media exposure is an acute environmental trigger for psychological disturbance and binge initiation by dismantling fat media messages and experimentally manipulating messages. Undergraduate women (N=197) were assigned to one of four media message conditions: a fat negative …

Pictures With A Voice: Understanding The Everyday Lives Of Native Americans Of The Chickasaw Nation In Developing A Nutrition Social Marketing Campaign, Krystal Rebecca Bowen

Theses and Dissertations

Randomly selected Native American families eligible to receive commodity foods were provided cameras to take pictures of visual responses in the areas of: 1) primary food purchases, 2) family use of food, 3) family activities and information access, and 4) future goals of the family. Using a focus-group format, participants chose five pictures that represented the group’s consensual responses. Selected pictures and meaning were analyzed using thematic analysis procedures. Twelve families completed the project. There were four major themes: 1) the importance of family and the Native-American community, 2) health of individual and family including extended family as it pertains …

The Effects Of Glucose Tolerance, Hypertension, And Race On Heart Rate Variability, Qt Interval Duration, And Left Ventricular Hypertrophy In Overweight-Obese Adolescents, Shirleatha T. Lee

Theses and Dissertations (ETD)

The prevalence of childhood obesity has increased remarkably within the past ten years with black youth disproportionately affected. Childhood obesity is linked to cardiovascular risk. Purposes of this study were to explore relationships between cardiac autonomic risk factors of heart rate variability (HRV), QT corrected (QTc) Interval duration, and Cornell voltage measures for left ventricular hypertrophy (LVH) to body mass index (BMI), relative body mass index (RBMI), and blood pressure (BP) measures, and to examine the effects of impaired glucose tolerance (IGT), hypertension, and race on these cardiac autonomic risk factors in overweight-obese adolescents.

Methods: Overweight and obese adolescents (N …

A Statewide Intervention Reduces Bmi In Adults: Shape Up Rhode Island Results, Rena R. Wing, Angela Marinilli Pinto, Melissa M. Crane, Rajiv Kumar, Brad Weinberg, Amy A. Gorin

Publications and Research

Given the epidemic of obesity, approaches to weight loss that can be applied on a community, state, or national level are needed. We report results from Shape Up Rhode Island 2007 (SURI), a state-wide Internet based program involving team-based competition to increase physical activity and achieve weight loss. A total of 4,717 adults (84% female; mean BMI = 29.6 kg/m2 ) enrolled in the 16 week weight loss competition of SURI and 3311 completed at least 12 weeks. Completers reported losing 3.2 ± 3.4 kg, and 30% achieved a clinically significant weight loss of 5% or more. Although modest, these …

Effect Of Obesity On The Traditional And Emerging Cardiovascular Disease Risk Factors In African American Women, Queen Obiageli Henry-Okafor

Theses and Dissertations (ETD)

Background: Obesity is a growing health care concern with cardiovascular disease (CVD) implications. African American women (AAW) have the highest prevalence rate of obesity and highest CVD morbidity and mortality rate of all ethnic groups. The traditional CVD risk factors have not been sufficient to explain this disparity in disease prevalence and outcomes. Current knowledge is limited regarding the interaction between various levels of adiposity and both traditional and emerging CVD risk factors, particularly in AAW. This study sought to explore these interactions.

Methods: The study design was a cross-sectional, descriptive, correlational analysis of 48 AAW ages 18 to 45 …

Making Healthy Choices: Adolescent Preference Ratings Of School-Based Health Interventions, Nicholas Glover Baird

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This study investigated the effect of a Making Healthy Choices lesson on junior high school students' preference rankings of items used to motivate students to increase academic performance. Results indicated that the lesson resulted in increased ranking scores on healthy items. This study used an assessment procedure that may be used to identify healthy rewards that may motivate students to increase academic performance as well as practice healthy decision making to prevent obesity.

The Development And Pilot Of A Culinary Intervention Designed Using The Social Cognitive Theory To Teach Nutrition To Adolescent Girls, Julie Anne Chessen

Master's Theses

In the past 20 years, the way in which food is prepared has rapidly changed. Convenience has become a way of life and Americans have replaced meals made from scratch with meals that are quick and easy. During that time, body mass index has risen steadily. The prevalence of overweight and obesity among children has become common in the American population. “Pink Chefs,” a six-week culinary intervention for middle school girls 12 to 14-years-old, was developed and piloted to combat childhood obesity by teaching nutrition through basic cooking skills. The social cognitive theory was used as the theoretical framework. The …

The Nutrition Elite: Do Only The Highest Levels Of Caloric Knowledge, Obesity Knowledge, And Motivation Matter In Processing Nutrition Ad Claims And Disclosures?, J. Craig Andrews, Richard G. Netemeyer, Scot Burton

Marketing Faculty Research and Publications

This study examines the role of the highest levels of caloric knowledge, obesity consequences knowledge, and motivation to search for nutrition information in the processing of relative nutrient content claims in advertisements, such as “half the calories” or “half the fat,” for products relatively high in total calorie levels. After controlling for the impact of demographics, dietary habits, body mass index, relative ad claims and disclosures, perceived weight gain risk, and other variables, the authors find curvilinear (quadratic) effects for caloric knowledge, obesity consequences knowledge, and motivation to search for nutrition information on intent to buy an advertised, high-calorie snack …

An Examination Of Alcohol Use In The Gastric Bypass Patient, Kathleen Winston Phd, Msn, Rn

Dissertations

Introduction: Obesity and morbid obesity, along with their co-morbidities, are impacting the national and international healthcare delivery systems and policy agendas. Bariatric surgery is a dynamic and fast-changing medical and surgical practice designed to mitigate the consequences of 60 million obese adults in the United States alone. Alcohol consumption after gastric bypass surgery presents potential physiological and psychological problems. Purpose: Examine the prevalence and incidence of increased alcohol consumption among a group of post-gastric bypass patients; identify the relationship of the alcohol use with time since surgery, psychosocial issues (depressive symptomatology, anxiety, coping) and demographic variables. Theoretical Framework: Coping serves …

Mechanisms Of Regulation Of Proximal Tubule Sodium Transporters In Obesity-Induced Hypertension, Marta A. Ambrozewicz

Theses and Dissertations in Biomedical Sciences

Hypertension is one of the common complications of obesity. Using a rat model of diet induced obesity and hypertension we investigated some of the mechanisms that are involved in regulation of blood pressure in obesity. The first aim of this study was to determine the role of proximal tubule transporters on the renal sodium handling in obese hypertensive (OP) and lean normotensive (OR) rats. An acute increase in renal perfusion pressure resulted in a blunted natriuretic response in OP vs. OR rats and indicated that increased sodium reabsorption in the proximal tubule is casual, at least in part, for hypertension …

The Effect Of Obesity On Serum Leptin And Lipid Profile, Kismat Mohammad Turki

Iraqi Postgraduate Medical Journal

ABSTRACT: BACKGROUND: Obesity has become a leading health concern; this condition is a chronic, complex, multifactorial disease in which a person's weight is ≥ 20% of the ideal weight for a given height. OBJECTIVE: To measure serum leptin level and lipid profiles levels in Iraqi obese individuals comparing the results with matching non obese subjects. METHODS: The study was carried on 30 individuals divided into two groups: 1. Obese subjects group (n=20). 2. Non-obese subjects group (n=10). For all subjects studied measurements of fasting serum leptin and lipid profile have been done. RESULT: Our study showed that mean serum leptin …

The Association Between Pediatric Overweight And Ankle Injuries: A Case-Control Analysis, Ellen Margaret House

Yale Medicine Thesis Digital Library

Pediatric obesity has become a worldwide pandemic and trauma is the leading cause of pediatric morbidity and mortality. Our hypothesis is that being overweight increases the likelihood of acute ankle injuries in children. Our study consisted of a case-control analysis in an urban pediatric emergency department with subjects between 5-19 years of age. Cases consisted of children presenting with acute ankle injury; controls had chief complaints of fever, headache, or sore throat. Demographic information, physical activity score, heights, and weights were obtained on all participants; injury severity was calculated for the cases. Age and gender specific body mass index percentiles …

Prevalence Of Obesity In School-Going Children Of Karachi., Haider Javed Warraich, Faisal Javed, Mohammed Faraz-Ul-Haq, Fariha Batool Khawaja, Sarah Saleem

Community Health Sciences

Background: Obesity is an emerging problem in Pakistan. The authors sought to determine prevalence of obesity and malnutrition in school-going children, from grades 6(th) to 8(th) of different schools of Karachi and assess associations that affect the weight of the children.
Methodology/Principal Findings: A cross sectional Study Design with children studying in grades 6(th) to 8(th) grade, in different schools of Karachi. We visited 10 schools of which 4 consented, two subsidized government schools and two private schools. A questionnaire was developed in consultation with a qualified nutritionist. Height and weight were measured on calibrated scales. A modified BMI criterion …

Health Professionals’ Roles In Animal Agriculture, Climate Change, And Human Health, Aysha Z. Akhtar, Michael Greger, Hope Ferdowsian, Erica Frank

Human Health Collection

What we eat is rapidly becoming an issue of global concern. With food shortages, the rise in chronic disease, and global warming, the impact of our dietary choices seems more relevant today than ever. Globally, a transition is taking place toward greater consumption of foods of animal origin, in lieu of plantbased diets. With this transition comes intensification of animal agriculture that in turn is associated with the emergence of zoonotic infectious diseases, environmental degradation, and the epidemics of chronic disease and obesity. Health professionals should be aware of these trends and consider them as they promote healthier and more …

Endothelial Progenitor Cell Number And Colony-Forming Capacity In Overweight And Obese Adults, O J Maceneaney, E J Kushner, Gary P. Van Guilder, J J Greiner, B L Stauffer, C A Desouza

Health and Nutritional Sciences Faculty Publications

OBJECTIVE: To investigate whether adiposity influences endothelial progenitor cell (EPC) number and colony-forming capacity.
DESIGN: Cross-sectional study of normal weight, overweight and obese adult humans.
PARTICIPANTS: Sixty-seven sedentary adults (aged 45-65 years): 25 normal weight (body mass index (BMI) or=30 kg/m(2); 18 males/6 females). All participants were non-smokers and free of overt cardiometabolic disease.
MEASUREMENTS: Peripheral blood samples were collected and circulating EPC number was assessed by flow cytometry. Putative EPCs were defined as CD45(-)/CD34(+)/VEGFR-2(+)/CD133(+) or CD45(-)/CD34(+) cells. EPC colony-forming capacity was measured in vitro using a colony-forming unit (CFU) assay.
RESULTS: Number of circulating putative EPCs (either CD45(-)/CD34(+)/VEGFR-2(+)/CD133(+) or …

Environment And Obesity In The National Children's Study, Leonardo Trasande, Christine E. Cronk, Maureen S. Durkin, Marianne E. Weiss, Dale A. Schoeller, Elizabeth A. Gall, Jeanne B. Hewitt, Aaron L. Carrel, Philip J. Landrigan, Matthew W. Gillman

College of Nursing Faculty Research and Publications

Objective: In this review we describe the approach taken by the National Children’s Study (NCS), a 21-year prospective study of 100,000 American children, to understanding the role of environmental factors in the development of obesity.

Data sources and extraction: We review the literature with regard to the two core hypotheses in the NCS that relate to environmental origins of obesity and describe strategies that will be used to test each hypothesis.

Data synthesis: Although it is clear that obesity in an individual results from an imbalance between energy intake and expenditure, control of the obesity epidemic will require understanding of …

Impact Of Obesity On Perioperative Morbidity And Mortality Following Pancreaticoduodenectomy, Timothy K. Williams, Ernest L. Rosato, Eugune P. Kennedy, Karen A. Chojnacki, Jocelyn Andrel, Terry Hyslop, Cataldo Doria, Patricia K. Sauter, Jordan Bloom, Charles J. Yeo, Adam C. Berger

Department of Surgery Faculty Papers

Background: Obesity has been implicated as a risk factor for perioperative and postoperative complications. The aim of this study was determine the impact of obesity on morbidity and mortality in patients undergoing pancreaticoduodenectomy (PD).

Study Design: Between January 2000 and July 2007, 262 patients underwent PD at Thomas Jefferson University Hospital (TJUH), of whom 240 had complete data, including body mass index (BMI) for analysis. Data on BMI, preoperative parameters, operative details, and post-operative course were collected. Patients were categorized as obese (BMI >30 kg/m2), overweight (25≤BMI<30), or normal weight (BMI<25). Complications were graded according to previous published scales. Other endpoints included length of postoperative hospital stay, blood loss, and operative duration. Analyses were performed using univariate and multivariable models.

Results: There were 103 (42.9%) normal weight, 71 (29.6%) overweight and 66 (27.5%) …

Race And Obesity: An Exploratory Analysis Of Perceptions And Experiences Related To Weight Among Black And White Adults, Kayla Jade Santalla

Open Access Theses

This thesis explores race and gender differences in perceptions and behaviors regarding weight and obesity, along with the relative influence of individual and structural factors on the personal weight status of black and white adults. In addition, this study examines the extent to which black and white adults differ in their perceptions of discrimination attributed to their personal weight. Based on an analysis of data from a national poll conducted by ABC News and TIME magazine, results indicate that weight status perceptions of overweight black females were consistent, while incongruity was found in perceived and actual weight status among obese …

Does The Perception Of Obesity Cause Discrimination In The American Workplace?, Kevin R. Anderson

Theses, Dissertations and Capstones

This thesis addresses the problem of discrimination facing the obese in America, specifically the discrimination the obese population contends with in the work place. The purpose of this study is to show the scope of the obesity problem across the United States, stigmas placed on the obese, sociological perceptions regarding the obese, and discrimination that the obese face in the work place.

Despite reports on the growing problem of obesity in America, little is known about the perspectives of the obese themselves, especially regarding discrimination in the work place. Literature is largely negative, relating the obese with undesirable traits and …

Educating Parents About The Epidemic Our Society Is Facing : Child Obesity, Jesus Narez

Capstone Projects and Master's Theses

This project is intended to increase the awareness of child obesity among parents in the Alisal community. For this project I will be working with the Alisal Healthy Start Program in Salinas to educate parents about the epidemic we are currently facing on child obesity. For this project I will be attending different adult classes to inform parents about the issue. My goal for the project would be to increase the awareness of child obesity and so parents can help their children.

Chasms In Care: Implications Of A Disparate System On Childhood Obesity, Sara Dianne Miller

Mahurin Honors College Capstone Experience/Thesis Projects

There are disparities that exist between public health and personal health care in addressing childhood obesity. Public health efforts to reduce the prevalence of this epidemic have focused on preventive strategies because a coordinated system of health care to address the treatment of obesity in children does not exist. For children who are already overweight, these strategies are not enough. What programs do exist are typically fee-for-service. This study examines the ethics and implications of the disparities that exists in our nation, as well as the role socioeconomic status plays in adolescent overweight and obesity and its primary behavior risk …

The Determinants Of Obesity Rates: A Municipal-Level Empirical Analysis, Elena Triebskorn

Theses & Honors Papers

The purpose of this study is to determine the determinants of obesity rates across metropolitan areas in the United States. Using Ordinary least squares analysis, this study examines the significance of 14 independent variables on the percentage of population overweight and /or obese for 127 metropolitan areas in the United States. Results suggest that income is a significant determinant of obesity rates. Obesity rates increase significantly for metropolitan areas with lower average median incomes. The study also finds that policy variables such as physical education requirements in schools and BMI information collected from children have a significant effect on the …

Hyperandrogenism And Obesity: Ominous Co-Morbidities, Amit M. Deokar, Shawn J. Smith, Amanda J. Goodwin, Hatim A. Omar

Pediatrics Faculty Publications

This review has a two-fold objective. One, it addresses the association of hyperandrogenism and obesity and the complex metabolic derangements that are part of the problem. Clinical management of these co-morbidities is challenging and complex. Second, this article will aid health care providers with the key features to an early diagnosis and intervention to decrease the morbidities in the short as well as long term. Method: Systematic review of articles and information on the topic of interest that were published in the last 15 years. Conclusion: Obesity and hyperandrogenism are integral parts of Metabolic Syndrome/Polycystic Ovarian Syndrome (PCOS)/Hyperandrogenism, Insulin resistance, …