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Demystifying Multiple Sclerosis Diagnosis Using Interpretable And Understandable Artificial Intelligence, Krishnaraj Chadaga, Varada Vivek Khanna, Srikanth Prabhu, Niranjana Sampathila

Open Access archive

Multiple sclerosis (MS) is a dangerous illness that strikes the central nervous system. The body's immune system attacks myelin (an entity above the nerves) and impairs brain-to-body communication. To date, it is not possible to cure MS. However, symptoms can be managed, and treatments can be provided if the disease is diagnosed early. Hence, supervised machine learning (ML) algorithms and several hyperparameter tuning techniques, including Bayesian optimization, have been utilized in this study to predict MS in patients. Descriptive and inferential statistical analysis has been conducted before training the classifiers. The most essential markers were chosen using a technique called …

Listening To Black Holes Ring: High-Precision Ringdown Modelling, Lorena Magaña Zertuche

Electronic Theses and Dissertations

After decades of promise, gravitational waves from a binary black hole system were detected on September 14, 2015 by the Laser Interferometer Gravitational-Wave Observatory (LIGO). Since then, close to 100 new gravitational-wave detections, including those from neutron star and neutron star-black hole binaries, have been made jointly by the LIGO, Virgo, and KAGRA (LVK) collaboration. LIGO's fourth observing run (O4) has begun, and signals on the order of one per week are expected. This rate will only increase as third-generation ground-based detectors will be getting hundreds of thousands of gravitational-wave signals when they go online in the next decade. Moreover, …

Efficient Design Of Neural Network Hardware Accelerator For Enhanced Performance In Deep Learning Systems, Tamador Nadem Mohaidat

Electronic Theses and Dissertations

Artificial intelligence (AI) hardware accelerator is an emerging research for several applications and domains. The hardware accelerator aims to provide high computational speed while retaining low cost and high learning performance. The main challenge is to design complex machine learning models on hardware with high performance. In this thesis, the aim is to develop the hardware implementation of perceptron within a neural network. Innovative hardware-based approaches are explored to optimize perceptron networks, enhancing accuracy, reliability, and fault tolerance while minimizing resource requirements and power consumption.

A thorough investigation into machine learning accelerators and associated challenges was initially conducted. The hardware …

Evaluating Pre-Trial Programs Using Interpretable Machine Learning Matching Algorithms For Causal Inference, Travis Seale-Carlisle, Saksham Jain, Courtney Lee, Caroline Levenson, Swathi Ramprasad, Brandon Garrett, Sudeepa Roy, Cynthia Rudin, Alexander Volfovsky

Faculty Scholarship

After a person is arrested and charged with a crime, they may be released on bail and required to participate in a community supervision program while awaiting trial. These ‘pretrial programs’ are common throughout the United States, but very little research has demonstrated their effectiveness. Researchers have emphasized the need for more rigorous program evaluation methods, which we introduce in this article. We describe a program evaluation pipeline that uses recent interpretable machine learning techniques for observational causal inference, and demonstrate these techniques in a study of a pre-trial program in Durham, North Carolina. Our findings show no evidence that …

Integrative Machine Learning Approaches For Enhanced Classification Of Genomic Sequences: A Next-Generation Sequencing Perspective, Sujatha Alla, Nagesh Bheesetty, Sai Gireesh Komaragiri, Prasanthi Chidipudi, Joshit Mohanty, Sathish Kumar Chintala, Jubin Thomas, Jayapal Vummadi, Hemanth Volikatla, Navin Kamuni

Engineering Management & Systems Engineering Faculty Publications

The advent of Next-Generation Sequencing (NGS) techniques has revolutionized genomic research by enabling the rapid sequencing of DNA and RNA. This data can be used for various applications, including genome sequencing, transcriptome profiling, metagenomics, and epigenetics studies. For this study, DNA classifier dataset was extracted from UCI repository of machine learning databases. This vast amount of genomic data necessitates the development of sophisticated machine learning (ML) models for effective classification and analysis. This study presents a comprehensive comparison of various ML models, including Support Vector Machines (SVM), Random Forests (RF), and Neural Networks (NNs), approaches, in classifying genomic data. We …

Integrating Generative Artificial Intelligence With Systems Architecting Diagram Creation: Advancement, Challenges, Opportunities And Future Perspectives, Cansu Yalim, Holly H. Handley

Engineering Management & Systems Engineering Faculty Publications

Generative AI (GenAI) serves as a powerful tool that can create a wide range of content, including but not limited to text, speech, images, code, videos, and 3D models. ChatGPT stands out as a particularly appealing Generative Pretrained Transformer (GPT) model that offers supplementary capabilities through GPTs and plugins. These extensions enable users to engage with the chatbot and improve its functionality, surpassing mere content generation. Our study delves into the potential of ChatGPT, specifically GPT-4, to expedite the creation of diagrams to support the system architecting process. To this end, we explored the use of ChatGPT's Diagrams Show Me …

Efficiently Learning An Encoder That Classifies Token Replacements And Masked Permuted Network-Based Bigru Attention Classifier For Enhancing Sentiment Classification Of Scientific Text, Muhammad Inaam Ul Haq, Khalid Mahmood, Qianmu Li, Ashok Kumar Das, Sachin Shetty, Majid Hussain

VMASC Publications

The exponential growth of scientific literature in digital repositories poses challenges in interpreting complex attitudes within academic texts. Traditional sentiment analysis methods often struggle with nuanced word meanings due to contextual variations. To address this, we propose the Electra-MPNet-based BiGRU attention classifier that extracts the high-level semantic features from citation sentences using the combined strength of Electra and MPNet encoder layers. These features are then combined to extract long-range dependencies through a stacked BiGRU layer. A linear attention mechanism is imposed to estimate the attention weights and context vector which enables the model to selectively focus on relevant information. The …

Machine Learning As A Tool For Early Detection: A Focus On Late-Stage Colorectal Cancer Across Socioeconomic Spectrums, Hadiza Galadima, Rexford Anson-Dwamena, Ashley Johnson, Ghalib Bello, Georges Adunlin, James Blando

Community & Environmental Health Faculty Publications

Purpose: To assess the efficacy of various machine learning (ML) algorithms in predicting late-stage colorectal cancer (CRC) diagnoses against the backdrop of socio-economic and regional healthcare disparities. Methods: An innovative theoretical framework was developed to integrate individual- and census tract-level social determinants of health (SDOH) with sociodemographic factors. A comparative analysis of the ML models was conducted using key performance metrics such as AUC-ROC to evaluate their predictive accuracy. Spatio-temporal analysis was used to identify disparities in late-stage CRC diagnosis probabilities. Results: Gradient boosting emerged as the superior model, with the top predictors for late-stage CRC diagnosis being anatomic site, …

Reducing The Uncertainty In Estimating Soil Microbial-Derived Carbon Storage, Han Hu, Chao Qian, Ke Xue, Rainer Georg Jörgensen, Marco Keiluweit, Chao Liang, Xuefeng Zhu, Ji Chen, Yishen Sun, Haowei Ni, Jixian Ding, Weigen Huang, Jingdong Mao, Rong-Xi Tan, Jizhong Zhou, Thomas W. Crowther, Zhi-Hua Zhou, Jiabao Zhang, Yuting Liang

Chemistry & Biochemistry Faculty Publications

Soil organic carbon (SOC) is the largest carbon pool in terrestrial ecosystems and plays a crucial role in mitigating climate change and enhancing soil productivity. Microbial-derived carbon (MDC) is the main component of the persistent SOC pool. However, current formulas used to estimate the proportional contribution of MDC are plagued by uncertainties due to limited sample sizes and the neglect of bacterial group composition effects. Here, we compiled the comprehensive global dataset and employed machine learning approaches to refine our quantitative understanding of MDC contributions to total carbon storage. Our efforts resulted in a reduction in the relative standard errors …

Multiview Outlier Filtered Pediatric Heart Sound Classification, Sagnik Dakshit

Computer Science Faculty Publications and Presentations

The advancements in deep learning has generated a large-scale interest in development of black-box models for various use cases in different domains such as healthcare, in both at-home and critical setting for diagnosis and monitoring of various health conditions. The use of audio signals as a view for diagnosis is nascent and the success of deep learning models in ingesting multimedia data provides an opportunity for use as a diagnostic medium. For the widespread use of these decision support systems, it is prudent to develop high performing systems which require large quantities of data for training and low-cost method of …

Machine-Learning-Enabled Diagnostics With Improved Visualization Of Disease Lesions In Chest X-Ray Images, Md. Fashiar Rahman, Tzu-Liang (Bill) Tseng, Michael Pokojovy, Peter Mccaffrey, Eric Walser, Scott Moen, Alex Vo, Johnny C. Ho

Mathematics & Statistics Faculty Publications

The class activation map (CAM) represents the neural-network-derived region of interest, which can help clarify the mechanism of the convolutional neural network’s determination of any class of interest. In medical imaging, it can help medical practitioners diagnose diseases like COVID-19 or pneumonia by highlighting the suspicious regions in Computational Tomography (CT) or chest X-ray (CXR) film. Many contemporary deep learning techniques only focus on COVID-19 classification tasks using CXRs, while few attempt to make it explainable with a saliency map. To fill this research gap, we first propose a VGG-16-architecture-based deep learning approach in combination with image enhancement, segmentation-based region …

Identifying The Origins Of Business’ Data Breaches Utilizing Covert Timing Channels, Gayle L. Frisbie

Master's Theses and Doctoral Dissertations

Cybersecurity events and data breaches are on the rise and are very costly to businesses. Businesses rely on connectivity and information systems to conduct business, yet those same information systems can be breached and the organization's data exposed. Today, there is a heavy reliance of organizations upon network connections to connect the entire organization in order to conduct business efficiently and from multiple locations. Covert timing channels are a cybersecurity attack method in which malicious actors embed privileged information into normal network traffic without authorization. Malicious actors, by carefully manipulating timing patterns in covert timing channels, can create a hidden …

A Data-Driven Machine Learning Approach For Electron-Molecule Ionization Cross Sections, Allison Harris, Josh Nepomuceno

Faculty publications – Physics

Despite their importance in a wide variety of applications, the estimation of ionization cross sections for large molecules continues to present challenges for both experiment and theory. Machine learning (ML) algorithms have been shown to be an effective mechanism for estimating cross section data for atomic targets and a select number of molecular targets. We present an efficient ML model for predicting ionization cross sections for a broad array of molecular targets. Our model is a 3-layer neural network that is trained using published experimental datasets. There is minimal input to the network, making it widely applicable. We show that …

Analysis And Detection Of Cyber Attacks In Multi Vehicle Systems Using Macroscopic Models, Abhishek Kashyap

Mechanical and Aerospace Engineering Dissertations - Archive

The study of potential cyber-attacks in different domains is an active area of research. Given that systems are becoming more and more interconnected, cyber physical systems that operate infrastructure and/or plants can make these assets more vulnerable and open to different attack vectors. The primary focus of this research is the modeling, analysis and detection of cyber-attacks on platoons of autonomous cars and swarms of UAVs. In this work, we consider scenarios wherein an attacker may hack into a subset of vehicles in a multi-vehicle system and make subtle modifications in their parameters. Due to the interconnected nature of the …

Integrating Machine Learning With Cure Models And Associated Inference, Wisdom Aselisewine

Mathematics Dissertations - Archive

Recent advancements in medical treatments have significantly enhanced the rates of recovery for numerous chronic illnesses. This progress has sparked growing interest in developing suitable statistical models capable of handling survival data that includes substantial cure fractions. The mixture cure model finds extensive application in analyzing survival data when there exists a cured subgroup. Standard logistic regression-based approaches for modeling the incidence part of the mixture cure model may suffer from poor predictive accuracy, especially in the presence of high dimensional covariates and/or non-linear covariate effects. To overcome this limitation, we propose the integration of distinct machine learning algorithms with …

Visualizing And Automating Past, Real-Time, And Forecast Dynamic Hazard Maps For Shallow Colluvial Landslides In Eastern Kentucky, Nathaniel O'Leary

Theses and Dissertations--Earth and Environmental Sciences

Landslide hazards are a persistent threat to communities and infrastructure in Eastern Kentucky, where steep slopes, shallow colluvial soils, and variable hydrological conditions make slope failures frequent. This thesis presents an integrated approach to landslide hazard mapping (LHM) through the development of dynamic, spatiotemporal LHMs for shallow colluvial landslides. Two studies within this work investigate and refine the use of the Lu and Godt (2008) factor of safety (FS) equation to improve landslide predictions. The first study establishes a novel LHM workflow using Hydrus-1D to simulate soil moisture infiltration and fluctuations from precipitation and evapotranspiration (ET) data. This study also …

Digital Image Correlation Guided Wearable Sensor Design And Fabrication Of Novel Microfluidic Pump For Human Movement Classification Using Machine Learning Models, Nick Cmager

Bioengineering Master's Theses

Wearable technologies are transforming healthcare and enabling physicians to customize treatments through continuous non-invasive data acquisition. Microfluidic sensors have been gaining attention due to their flexibility and ability to conform to the human skin. However, individual variations in skin properties necessitate personalized sensor designs. This thesis presents a novel approach for designing and fabricating wearable microfluidic sensors, leveraging digital image correlation (DIC) to guide the development of a microfluidic pump for human movement classification. An open-source DIC platform Ncorr was utilized for 2D and 3D DIC analysis of human skin strain. The results were used to guide the design of …

Towards Machine Learning-Based Control Of Autonomous Vehicles In Solar Panel Cleaning Systems, Farima Hajiahmadi

Theses and Dissertations

This thesis presents a machine learning (ML)-based approach for the intelligent control of Autonomous Vehicles (AVs) utilized in solar panel cleaning systems, aiming to mitigate challenges arising from uncertainties, disturbances, and dynamic environments. Solar panels, predominantly situated in dedicated lands for solar energy production (e.g., agricultural solar farms), are susceptible to dust and debris accumulation, leading to diminished energy absorption. Instead of labor-intensive manual cleaning, robotic cleaners offer a viable solution. AVs equipped to transport and precisely position these cleaning robots are indispensable for efficient navigation among solar panel arrays. However, environmental obstacles (e.g., rough terrain), variations in solar panel …

Understanding Data Through The Lens Of Topology, Quang Truong

Dartmouth College Master’s Theses

Machine learning depends on the ability to learn insightful representations from data. Topology of data offers a rich source of information for constructing such representations, yet its potential remains under-explored by the broader machine learning community. This work investigates the power of applied topology through two complementary projects: Topological Message Passing with Path Complexes and Persistent Homology for Anomaly Detection. In the first project, we extend the topological message passing framework by introducing a novel approach centered on path complexes, where paths form the fundamental building blocks. Our theoretical analysis demonstrates that this model generalizes existing topological deep learning and …

An Investigation Into The Role Of Machine Learning And Deep Learning Models As A Means Of Leveraging The Ever-Expanding Volume Of Astronomical Data To Automate Stellar Classification., Gerard Heraghty

ICT

This research investigates the use of machine learning and neural network models for automated stellar classification in large astronomical surveys, addressing challenges posed by the increasing volume of data. Using the MK scheme as the classification standard, the study focused on spectroscopic data and balanced the dataset using SMOTE techniques to handle class imbalances. Various models, including Random Forest, SVM, MLP, and CNN, were trained and compared for classifying MK main and sub-classes. CNN achieved the highest accuracy (93.86%) for main class classification, while SVM excelled at sub-class classification (63.23%) on balanced datasets. However, when tested on real-world SDSS data, …

Accelerating Cavity Fault Prediction Using Deep Learning At Jefferson Laboratory, Md M. Rahman, A. Carpenter, K. Iftekharuddin, C. Tennant

Electrical & Computer Engineering Faculty Publications

Accelerating cavities are an integral part of the continuous electron beam accelerator facility (CEBAF) at Jefferson Laboratory. When any of the over 400 cavities in CEBAF experiences a fault, it disrupts beam delivery to experimental user halls. In this study, we propose the use of a deep learning model to predict slowly developing cavity faults. By utilizing pre-fault signals, we train a long short-term memory-convolutional neural network binary classifier to distinguish between radio-frequency (RF) signals during normal operation and RF signals indicative of impending faults. We optimize the model by adjusting the fault confidence threshold and implementing a multiple consecutive …

Comparative Analysis Of Machine Learning Models For Predicting Healthcare Traffic: Insights For Optimized Emergency Response, Shadman Mahmood Khan Pathan, Sakan Binte Imran, M. M. Shabab Iqbal, Muhammad Enayetur Rahman, Md. Nurul Absar Siddiky, Muhammad Rezaur Rahman, Md Rafid Hasan, Nondon Lal Dey, Md Sobuj Hossain

Electrical & Computer Engineering Faculty Publications

Efficient management of healthcare traffic is crucial for ensuring timely access to medical services, particularly in emergency situations where delays can have severe consequences. This study presents a comparative analysis of three widely used machine learning models—Linear Regression, Decision Trees, and Random Forests—aimed at predicting healthcare-related traffic volumes. A large dataset from a metropolitan traffic system was used to train and evaluate the models based on key performance indicators, including Mean Squared Error (MSE), R² Score, and computational efficiency. The results reveal that the Random Forest model offers the best performance, achieving higher predictive accuracy and faster execution times compared …

Predictive Modeling Of Healthcare Traffic Using Machine Learning: A Comparative Study, Shadman Mahmood Khan Pathan, Sakan Binte Imran, M. M. Shabab Iqbal, Muhammad Enayetur Rahman, Md Nurul Absar Siddiky, Muhammad Rezaur Rahman, Md. Rafid Hassan, Nondon Lal Dey, Md. Sobuj Hossain

Electrical & Computer Engineering Faculty Publications

Effective healthcare traffic management is critical for ensuring prompt medical services, particularly in emergencies where delays can have life-threatening consequences. This study conducts a comparative analysis of three popular machine learning models—Linear Regression, Decision Trees, and Random Forests—for predicting healthcare-related traffic volumes. Utilizing a comprehensive dataset from a metropolitan interstate traffic system, the models were evaluated based on key performance metrics, including Mean Squared Error (MSE), R² Score, and execution time. The findings demonstrate that the Random Forest model outperforms the others, offering superior predictive accuracy and efficiency. These insights are valuable for optimizing traffic management in healthcare, ultimately contributing …

Classification Of Instructional Activities In Classroom Videos Using Neural Networks, Jonathan K. Foster, Matthew Korban, Peter Youngs, Ginger S. Watson, Scott T. Acton

VMASC Publications

Classroom videos have become an integral part of classroom observation and instructional quality studies. Researchers encounter substantial financial and time-consuming costs gathering trained personnel to catalogue and analyze a large quantity (i.e., hundreds of hours) of classroom videos. In this chapter, we argue that deep-learning neural networks have potential to help with these tasks by detecting features of instruction in videos. We evaluated the performance of three neural networks in detecting instructional activities in classroom videos. The video dataset included a total of forty-six hours, which was evenly split between elementary mathematics and English language arts lesson recordings. Results showed …

Monotone Ordinal Expert Knowledge Acquisition For Explanation Of Machine Learning Models, Harlow Huber

All Master's Theses

There are significant difficulties for the acceptance of black-box Machine Learning (ML) models by subject matter experts (SMEs) despite significant achievements of many black-box models. A promising way to address this problem is by building a trustable, qualitative, interpretable models for the task based on SME knowledge. Such qualitative models can work as qualitative explainers of black-box models or as sanity checks for them. For instance, the expert model can expect that two cases belong to different classes, but the black box model predicts that they are in the same class. In this thesis, qualitative models operate with ordinal attributes, …

Building A Human Digital Twin (Hdtwin) Using Large Language Models For Cognitive Diagnosis: Algorithm Development And Validation, Gina Sprint, Maureen Schmitter-Edgecombe, Diane Cook

Computer Science Faculty Scholarship

Background: Human digital twins have the potential to change the practice of personalizing cognitive health diagnosis because these systems can integrate multiple sources of health information and influence into a unified model. Cognitive health is multifaceted, yet researchers and clinical professionals struggle to align diverse sources of information into a single model. Objective: This study aims to introduce a method called HDTwin, for unifying heterogeneous data using large language models. HDTwin is designed to predict cognitive diagnoses and offer explanations for its inferences. Methods: HDTwin integrates cognitive health data from multiple sources, including demographic, behavioral, ecological momentary assessment, n-back test, …

Deep Transfer Learning-Based Bird Species Classification Using Mel Spectrogram Images, Mrinal Kanti Baowaly, Bisnu Chandra Sarkar, Md.Abul Ala Walid, Md. Martuza Ahamad, Bikash Chandra Singh, Eduardo Silva Alvarado, Imran Ashraf, Md. Abdus Samad

School of Cybersecurity Faculty Publications

The classification of bird species is of significant importance in the field of ornithology, as it plays an important role in assessing and monitoring environmental dynamics, including habitat modifications, migratory behaviors, levels of pollution, and disease occurrences. Traditional methods of bird classification, such as visual identification, were time-intensive and required a high level of expertise. However, audio-based bird species classification is a promising approach that can be used to automate bird species identification. This study aims to establish an audio-based bird species classification system for 264 Eastern African bird species employing modified deep transfer learning. In particular, the pre-trained EfficientNet …

Mlp And Rbf Algorithms In Finance: Predicting And Classifying Stock Prices Amidst Economic Policy Uncertainty, Bushra Ali, Khder Alakkari, Mostafa Abotaleb, Maad M. Mijwil, Klodian Dhoska

Mesopotamian Journal of Big Data

In the realm of stock market prediction and classification, the use of machine learning algorithms has gained significant attention. In this study, we explore the application of Multilayer Perceptron (MLP) and Radial Basis Function (RBF) algorithms in predicting and classifying stock prices, specifically amidst economic policy uncertainty. Stock market fluctuations are greatly influenced by economic policies implemented by governments and central banks. These policies can create uncertainty and volatility, which in turn makes accurate predictions and classifications of stock prices more challenging. By leveraging MLP and RBF algorithms, we aim to develop models that can effectively navigate these uncertainties and …

Lidar From The Sky: Uav Integration And Fusion Techniques For Advanced Traffic Monitoring, Baya Cherif, Hakim Ghazzai, Ahmad Alsharoa

Electrical and Computer Engineering Faculty Research & Creative Works

Light detection and ranging (LiDAR) technology's expansion within the autonomous vehicles industry has rapidly motivated its application in numerous growing areas, such as smart cities, agriculture, and renewable energy. In this article, we propose an innovative approach for enhancing aerial traffic monitoring solutions through the application of LiDAR technology. The objective is to achieve precise and real-time object detection and tracking from aerial perspectives by integrating unmanned aerial vehicles with LiDAR sensors, thereby creating a potent Aerial LiDAR (A-LiD) solution for traffic monitoring. First, we develop a novel deep learning algorithm based on pointvoxel-region-based convolutional neural network (RCNN) to conduct …

Tailoring The Heat Pump System Controller To The Building: Assessment Of Adapted Heating Curves Using Data-Driven Methods, Florian Will, Jonas Klingebiel, Christian Vering, Dirk Müller

International High Performance Buildings Conference

No abstract provided.