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Rising Tide 2015, Une Office Of Research And Scholarship, Edward Bilsky, Annie Leslie, Josh Pahigian, Jennie E. Aranovitch, Laura M. Duffy, Marine Miller

Rising Tide

Research and scholarship highlights from University of New England community members. This issue highlights in particular: student and faculty research and projects within UNE's College of Arts and Sciences, College of Osteopathic Medicine, Westbrook College of Health Professions, and projects and research from UNE's Centers for Excellence.

Differential Proteomic Analysis Of Endemic And Sporadic Epstein-Barr Virus-Positive And Negative Burkitt Lymphoma, Nader Kim El-Mallawany, Nancy Day, Janet Ayello, Carmella Van De Ven, Kevin Conlon, Damian Fermin, Venkatesha Basrur, Kojo Elenitoba-Johnson, Megan Lim, Mitchell S. Cairo

NYMC Faculty Publications

BACKGROUND: Burkitt lymphoma (BL) is the most common non-Hodgkin lymphoma in children worldwide and the most common paediatric malignancy in sub-Saharan Africa. The endemic (eBL) and sporadic (sBL) variants have distinct epidemiologic and virologic characteristics. Although gene expression studies have defined the transcriptional profiles of both, their proteomic signatures have not been studied. METHODS: We compared the proteomic expression profiles using differential mass spectrometry-based isotope tag for relative and absolute quantitation (iTRAQ) analysis of a cell line representing Epstein-Barr virus (EBV)+ eBL, EBV+ and EBV- sBL, and EBV+/- normal B cells from healthy donors. RESULTS: In total, there were 144 …

Fact Book, 2015-16, John Carroll University

Fact Book

2015-16 Fact book

Nova Southeastern University 2015 Annual Report, Nova Southeastern University

NSU Annual Reports

No abstract provided.

2015 Nsu Fact Book, Office Of Institutional Research

NSU Fact Book

This 23rd edition of the Nova Southeastern University Fact Book reflects an expanding body of data and information that provides perspective on the university’s character, growth, and accomplishments.

The 2015 Fact Book includes narrative, numeric, and graphic representation of the university, including history, characteristics, and development of the institution. Data are presented in both tabular and graphic formats to provide pertinent detail, and general trends are highlighted.

Cavanaugh, Patrick Oral History Interview, David Fletcher

Emeriti Society Oral History Collection

Vice-President for Business and Finance (1997-2014). Topics include: business at Pacific, President DeRosa’s administration, beginning of President Eibeck’s administration (first five years), endowment growth, facility planning and development: 1997 – 2014

Heffernan, James Oral History Interview, David Fletcher

Emeriti Society Oral History Collection

Professor of Philosophy (1972-2014) The path to Pacific, contributions including innovations and new courses, Department of Philosophy, student trends, and changes and impact of administration. Changes in Pacific over time including: ethnic make-of students, use of technology, and community involvement.

Muskal, Fred Oral History Interview, Roland Difranco

Emeriti Society Oral History Collection

Professor of Education Administration (1972-2009). Topics include: Chair Academic Council 1992, Education Administration, Information & Imagination Program (I&I), and faculty/administration interactions.

Howells, Gary Oral History Interview, Robert Dash

Emeriti Society Oral History Collection

Professor of Psychology (1971-2013). Topics include: Getting into Pacific, Callison College experience, integration into COP Psychology Department, clinical experience and the Stockton community, and relationships with colleagues and administrators.

Ua37/37 Faculty Personal Papers Arndt Stickles, Wku Archives

WKU Archives Collection Inventories

Personal papers of Arndt Stickles, WKU History professor from 1908-1954. The collection includes articles, speeches, lecture notes and correspondence.

Graduate Catalog, Georgia Southern University

Graduate Catalogs

No abstract provided.

The Disparity Of Racial Diversity In Counselor Education And Supervision, Sharon Hammett Webb

Walden Dissertations and Doctoral Studies

In general, doctoral programs in counselor education and supervision (CES) have low minority enrollments. Faculty members in clinical mental health counseling (CMHC) master's degree in science (MS) programs primarily come from CES doctoral programs; therefore, faculty members do not generally reflect the diversity of the MS student population. Using the theory of planned behavior and the bioecological model, the purpose of this research was to determine the extent to which age, gender, faculty support, income, level of parents' or primary caregivers' education, and the Council for Accreditation of Counseling and Related Educational Programs (CACREP) accreditation status predict White and racial …

Georgia Southern University Fact Book, Georgia Southern University

Georgia Southern Fact Books (1976-2022)

No abstract provided.

Wage Distribution Impacts Of Higher Education Faculty Unionization, Charles S. Wassell Jr., David W. Hedrick, Steven E. Henson, John M. Krieg

Economics Faculty Scholarship

The literature on the effects of unions on the distribution of wages at the macroeconomic and inter-industry levels has given little attention to the effects at the firm level. At the same time, research on collective bargaining impacts in higher education has focused on the overall wage level rather than on the distribution of salaries. Using panel data on individual faculty members, we find faculty unionization to be associated with a significant flattening of the wage distribution across academic disciplines. This has implications for why faculty might choose to unionize, even in the absence of an overall wage premium.

Undergraduate Catalog

Undergraduate & Graduate Catalogs

No abstract provided.

A Grounded Theory Model For Faculty Evaluation Of Nursing Student Performance During A Simulation, Penni Isla Watts

All ETDs from UAB

This qualitative grounded theory study explored the process of faculty evaluation of student performance during simulation in the southern United States. In the last decade, simulation experiences have been found to be useful in nursing education as a teaching methodology and as a potential method for evaluation of student performance. While clinical experiences are limited, unpredictable, and difficult to truly evaluate, simulation experiences provide an opportunity for students to manage care through pre-planned patient scenarios without potential harm to real patients. This allows faculty to observe students making decisions and caring for simulated patients in a context designed to elicit …

Cyp2j2 Targeting To Endothelial Cells Attenuates Adiposity And Vascular Dysfunction In Mice Fed A High-Fat Diet By Reprogramming Adipocyte Phenotype, Nader G. Abraham, Komal Sodhi, Anne M. Silvis, Luca Vanella, Gaia Favero, Rita Rezzani, Craig Lee, Darryl C. Zeldin, Michal L. Schwartzman

NYMC Faculty Publications

Obesity is a global epidemic and a common risk factor for endothelial dysfunction and the subsequent development of diabetes mellitus and vascular diseases such as hypertension. Epoxyeicosatrienoic acids (EETs) are cytochrome P450 (CYP)-derived metabolites of arachidonic acid that contribute to vascular protection by stimulating vasodilation and inhibiting inflammation. Heme oxygenase-1 is a stress response protein that plays an important cytoprotective role against oxidative insult in diabetes mellitus and cardiovascular disease. We recently demonstrated interplay between EETs and heme oxygenase-1 in the attenuation of adipogenesis. We examined whether adipocyte dysfunction in mice fed a high-fat diet could be prevented by endothelial-specific …

Α-Ketoglutaramate: An Overlooked Metabolite Of Glutamine And A Biomarker For Hepatic Encephalopathy And Inborn Errors Of The Urea Cycle, Arthur J. Cooper, Tomiko Kuhara

NYMC Faculty Publications

Glutamine metabolism is generally regarded as proceeding via glutaminase-catalyzed hydrolysis to glutamate and ammonia, followed by conversion of glutamate to α-ketoglutarate catalyzed by glutamate dehydrogenase or by a glutamate-linked aminotransferase (transaminase). However, another pathway exists for the conversion of glutamine to α-ketoglutarate that is often overlooked, but is widely distributed in nature. This pathway, referred to as the glutaminase II pathway, consists of a glutamine transaminase coupled to ω-amidase. Transamination of glutamine results in formation of the corresponding α-keto acid, namely, α-ketoglutaramate (KGM). KGM is hydrolyzed by ω-amidase to α-ketoglutarate and ammonia. The net glutaminase II reaction is: L - …

Modeling Colony Collapse Disorder In Honeybees As A Contagion, Christopher Kribs, Christopher Mitchell

Mathematics Faculty Publications - Archive

Honeybee pollination accounts annually for over $14 billion in United States agriculture alone. Within the past decade there has been a mysterious mass die-off of honeybees, an estimated 10 million beehives and sometimes as much as 90% of an apiary. There is still no consensus on what causes this phenomenon, called Colony Collapse Disorder, or CCD. Several mathematical models have studied CCD by only focusing on infection dynamics. We created a model to account for both healthy hive dynamics and hive extinction due to CCD, modeling CCD via a transmissible infection brought to the hive by foragers. The system of …

Kynurenine Aminotransferase Iii And Glutamine Transaminase L Are Identical Enzymes That Have Cysteine S-Conjugate Β-Lyase Activity And Can Transaminate L-Selenomethionine, John T. Pinto, Boris F. Krasnikov, Steven Alcutt, Melanie E. Jones, Thambi Dorai, Maria T. Villar, Antonio Artigues, Jianyong Li, Arthur J. Cooper

NYMC Faculty Publications

Three of the four kynurenine aminotransferases (KAT I, II, and IV) that synthesize kynurenic acid, a neuromodulator, are identical to glutamine transaminase K (GTK), α-aminoadipate aminotransferase, and mitochondrial aspartate aminotransferase, respectively. GTK/KAT I and aspartate aminotransferase/KAT IV possess cysteine S-conjugate β-lyase activity. The gene for the former enzyme, GTK/KAT I, is listed in mammalian genome data banks as CCBL1 (cysteine conjugate beta-lyase 1). Also listed, despite the fact that no β-lyase activity has been assigned to the encoded protein in the genome data bank, is a CCBL2 (synonym KAT III). We show that human KAT III/CCBL2 possesses cysteine S-conjugate β-lyase …

Research And Creative Activity July 1, 2013 – June 30, 2014: Major Sponsored Programs And Faculty Awards For Research And Creativity, Elizabeth Banset

Office of Research and Economic Development: Publications

This booklet highlights the successes of the University of Nebraska–Lincoln faculty during the fiscal year July 1, 2013-June 30, 2014. It lists the funding sources, projects and investigators on major grants and sponsored program awards received during the year; published books and scholarship; fellowships and other recognition; intellectual property licenses; and performances and exhibitions in the fine and performing arts.

Tsu Faculty Publication Database, David Owerbach

Office of Research Institutional Research and Scholarship

No abstract provided.

Kcnj10 Is A Major Type Of K+ Channel In Mouse Corneal Epithelial Cells And Plays A Role In Initiating Egfr Signaling, Lijun Wang, Chengbiao Zhang, Xiaotong Su, Daohong Lin

NYMC Faculty Publications

We used primary mouse corneal epithelial cells (pMCE) to examine the role of Kcnj10 in determining membrane K(+) conductance and cell membrane potential and in regulating EGF/TGFA release. Western blot, immunostaining, and RT-PCR detected the expression of Kcnj10 in mouse cornea. The single channel recording identified the 20-pS inwardly rectifying K(+) channels in pMCE of WT mice, but these channels were absent in Kcnj10(-/-). Moreover, the whole cell recording demonstrates that deletion of Kcnj10 largely abolished the inward K(+) currents and depolarized the cell membrane K(+) reversal potential (an index of the cell membrane potential). This suggests that Kcnj10 is …

Partial Blockade Of Nicotinic Acetylcholine Receptors Improves The Counterregulatory Response To Hypoglycemia In Recurrently Hypoglycemic Rats, Edmund F. Lagamma, Necla Kirtok, Owen Chan, Bistra B. Nankova

NYMC Faculty Publications

Recurrent exposure to hypoglycemia can impair the normal counterregulatory hormonal responses that guard against hypoglycemia, leading to hypoglycemia unawareness. This pathological condition known as hypoglycemia-associated autonomic failure (HAAF) is the main adverse consequence that prevents individuals with type 1 diabetes mellitus from attaining the long-term health benefits of tight glycemic control. The underlying molecular mechanisms responsible for the progressive loss of the epinephrine response to subsequent bouts of hypoglycemia, a hallmark sign of HAAF, are largely unknown. Normally, hypoglycemia triggers both the release and biosynthesis of epinephrine through activation of nicotinic acetylcholine receptors (nAChR) on the adrenal glands. We hypothesize …

Downregulation Of Cox-2 And Cyp 4a Signaling By Isoliquiritigenin Inhibits Human Breast Cancer Metastasis Through Preventing Anoikis Resistance, Migration And Invasion, Hao Zheng, Ying Li, Yuzhong Wang, Haixia Zhao, Jing Zhang, Hongyan Chai, Tian Tang, Jiang Yue, Austin M. Guo, Jing Yang

NYMC Faculty Publications

Flavonoids exert extensive in vitro anti-invasive and in vivo anti-metastatic activities. Anoikis resistance occurs at multiple key stages of the metastatic cascade. Here, we demonstrate that isoliquiritigenin (ISL), a flavonoid from Glycyrrhiza glabra, inhibits human breast cancer metastasis by preventing anoikis resistance, migration and invasion through downregulating cyclooxygenase (COX)-2 and cytochrome P450 (CYP) 4A signaling. ISL induced anoikis in MDA-MB-231 and BT-549 human breast cancer cells as evidenced by flow cytometry and the detection of caspase cleavage. Moreover, ISL inhibited the mRNA expression of phospholipase A2, COX-2 and CYP 4A and decreased the secretion of prostaglandin E2 (PGE2) and 20-hydroxyeicosatetraenoic …

Celebrating Faculty Scholarship: Bibliography - 2013, Loyola University Chicago

University Libraries: Faculty Publications and Other Works

A bibliography of faculty publications submitted for inclusion in the fifth annual 'Celebrating Faculty Scholarship' event sponsored by Loyola University Libraries. The event, which took place on October 21, 2014 in the Richard J. Klarchek Information Commons on the university's Lake Shore Campus, featured articles, books, creative works, and other materials authored by Loyola University Chicago faculty in 2013.

Exploring The Relationship Between Faculty Perceptions Of Chairperson-Faculty Member Communication Exchanges And Department Climate, Jodi Lynn Hallsten Lyczak

Theses and Dissertations

Leadership communication has many consequences: those that affect an organization and its outcomes, and those that affect the followers. In academia, one of the most important leadership roles is that of the departmental chairperson. Through her or his communication, the academic chairperson influences nearly every aspect of departmental life for faculty, including organizational climate. In fact, it can be argued that the chairperson helps both create and sustain the department climate for faculty.

One perspective of leadership and communication posits that leadership is enacted in the dyadic communication that occurs between the leader and the follower. According to Leader Member …

Pge(2) Ep(3) Receptor Downregulates Cox-2 Expression In The Medullary Thick Ascending Limb Induced By Hypertonic Nacl, Shoujin Hao, Alejandra Hernandez, Mariana Quiroz-Munoz, Carlos Cespedes, Carlos P. Vio, Nicholas R. Ferreri

NYMC Faculty Publications

We tested the hypothesis that inhibition of EP3 receptors enhances cyclooxygenase (COX)-2 expression in the thick ascending limb (TAL) induced by hypertonic stimuli. COX-2 protein expression in the outer medulla increased approximately twofold in mice given free access to 1% NaCl in the drinking water for 3 days. The increase was associated with an approximate threefold elevation in COX-2 mRNA accumulation and an increase in PGE2 production by isolated medullary (m)TAL tubules from 77.3 ± 8.4 to 165.7 ± 10.8 pg/mg protein. Moreover, administration of NS-398 abolished the increase in PGE2 production induced by 1% NaCl. EP3 receptor mRNA levels …

A Systems Approach Identifies Co-Signaling Molecules Of Early Growth Response 1 Transcription Factor In Immobilization Stress, Nikolaos A. Papanikolaou, Andrej Tillinger, Xiaoping Liu, Athanasios G. Papavassiliou, Esther L. Sabban

NYMC Faculty Publications

BACKGROUND: Adaptation to stress is critical for survival. The adrenal medulla, the major source of epinephrine, plays an important role in the development of the hyperadenergic state and increased risk for stress associated disorders, such as hypertension and myocardial infarction. The transcription factor Egr1 plays a central role in acute and repeated stress, however the complexity of the response suggests that other transcription factor pathways might be playing equally important roles during acute and repeated stress. Therefore, we sought to discover such factors by applying a systems approach. RESULTS: Using microarrays and network analysis we show here for the first …

Chicken Fetal Liver Dna Damage And Adduct Formation By Activation-Dependent Dna-Reactive Carcinogens And Related Compounds Of Several Structural Classes, Gary M. Williams, Jian-Dong Duan, Klaus D. Brunnemann, Michael J. Iatropoulos, Esther Vock, Ulrich Deschl

NYMC Faculty Publications

The chicken egg genotoxicity assay (CEGA), which utilizes the liver of an intact and aseptic embryo-fetal test organism, was evaluated using four activation-dependent DNA-reactive carcinogens and four structurally related less potent carcinogens or non-carcinogens. In the assay, three daily doses of test substances were administered to eggs containing 9-11-day-old fetuses and the fetal livers were assessed for two endpoints, DNA breaks using the alkaline single cell gel electrophoresis (comet) assay and DNA adducts using the (32)P-nucleotide postlabeling (NPL) assay. The effects of four carcinogens of different structures requiring distinct pathways of bioactivation, i.e., 2-acetylaminofluorene (AAF), aflatoxin B1 (AFB1), benzo[a]pyrene (B[a]P), …