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Reduced Intensity Conditioning And Hematopoietic Stem Cell Transplantation In Pediatric Nonmalignant Disease: A New Therapeutic Paradigm, Cori M. Abikoff, Mitchell S. Cairo May 2014

Reduced Intensity Conditioning And Hematopoietic Stem Cell Transplantation In Pediatric Nonmalignant Disease: A New Therapeutic Paradigm, Cori M. Abikoff, Mitchell S. Cairo

NYMC Faculty Publications

No abstract provided.


The Role Of Nonpharmacologic Device Interventions In The Management Of Drug-Resistant Hypertension, William H. Frishman, Daniel Glicklich May 2014

The Role Of Nonpharmacologic Device Interventions In The Management Of Drug-Resistant Hypertension, William H. Frishman, Daniel Glicklich

NYMC Faculty Publications

Resistant systemic hypertension in patients is defined as the inability to control blood pressure despite taking at least three antihypertensive drugs, one of which is a diuretic. Two nonpharmacologic approaches are being evaluated in resistant hypertensive patients. First, the Rheos® Baroreflex Hypertension Therapy system is an implantable device that activates the carotid baroreflex through electrical stimulation of the carotid sinus wall. Sustained and clinically lower blood pressure has been observed in patient clinical trials. The second approach is a catheter-based strategy which denervates the renal afferent and efferent autonomic nervous system. This strategy has also been shown to be effective …


The Scholarship Of Teaching At Community Colleges, Patrice Arleanor Williams May 2014

The Scholarship Of Teaching At Community Colleges, Patrice Arleanor Williams

Dissertations

This dissertation addresses engagement in the scholarship of teaching (SoT) at the community college level. A basic overview of the origin of the concept, a discussion of some of the key publications in the body of literature on the topic, and the details and results of a study on the topic—including suggestions for further research—are provided here.

The study involved full-time community college faculty members, representing institutions throughout the United States. Thirty-nine participants completed a 53-item questionnaire developed by the researcher. The goal of the study was to determine if a relationship existed between engagement in SoT and teaching satisfaction …


Race, Gender, And Faculty Advancement At American Colleges And Universities, James Sharell Bridgeforth May 2014

Race, Gender, And Faculty Advancement At American Colleges And Universities, James Sharell Bridgeforth

Dissertations

Women and people of color are underrepresented in the American professoriate; although the presence of female faculty and professors of color is beneficial to the academy on various levels, these groups often face many barriers and challenges throughout the promotion and tenure process. This study was designed to examine whether race, gender, or a combination of race and gender made a statistically significant difference in reported opportunities for mentorship, faculty socialization, and scholarship in regard to faculty advancement in the academy. Data were collected from 650 tenured and tenure-track faculty through an online questionnaire. The data analysis revealed that women …


Stress Levels In Tenure-Track And Recently Tenured Faculty Members In Selected Institutions Of Higher Education In Northeast Tennessee, Amanda R. Carr May 2014

Stress Levels In Tenure-Track And Recently Tenured Faculty Members In Selected Institutions Of Higher Education In Northeast Tennessee, Amanda R. Carr

Electronic Theses and Dissertations

The purpose of this quantitative study was to compare the stress, strain, and coping levels between pretenured faculty and recently tenured faculty in institutions of higher education in Northeast Tennessee. Aging faculty population combined with talented people leaving the area is common in rural parts of the United States. There is a need to better understand the occupational factors within the faculty roles in order to better recruit and retain faculty in this region.

Four different institutions of higher education in Northeast Tennessee, producing 92 responses, participated in this study. The Occupational Stress Inventory – Revised (Osipow, 1998) was used …


Corpus Linguistics Of The Vernacular: “Catching A Cold” In Text Types That Complement Google Books Data, Laurel Smith Stvan Apr 2014

Corpus Linguistics Of The Vernacular: “Catching A Cold” In Text Types That Complement Google Books Data, Laurel Smith Stvan

Linguistics & TESOL Faculty Publications & Presentations - Archive

Poster presented at the Texas Digital Humanities Consortium (TXDHC) on April 11, 2014


The Loop (Early Spring 2014), Taylor University Apr 2014

The Loop (Early Spring 2014), Taylor University

The Loop (2012-2017)

The early Spring 2014 edition of Taylor University’s The Loop.


The Loop (Late Spring 2014), Taylor University Apr 2014

The Loop (Late Spring 2014), Taylor University

The Loop (2012-2017)

The late Spring 2014 edition of Taylor University’s The Loop.


Five Relational Strategies For Mentoring Female Faculty, Tonya Hammer, Heather Trepal, Stacy Speedlin Apr 2014

Five Relational Strategies For Mentoring Female Faculty, Tonya Hammer, Heather Trepal, Stacy Speedlin

Adultspan Journal

No abstract provided.


Spring 2014, College Of The Pacific Apr 2014

Spring 2014, College Of The Pacific

History News

No abstract provided.


Mitochondrial Structure Alteration In Human Prostate Cancer Cells Upon Initial Interaction With A Chemopreventive Agent Phenethyl Isothiocyanate, Chengsen Xue, Hilda A. Pasolli, Irene Piscopo, Daniel J. Gros, Christina Liu, Yamei Chen, Jen Wei Chiao Mar 2014

Mitochondrial Structure Alteration In Human Prostate Cancer Cells Upon Initial Interaction With A Chemopreventive Agent Phenethyl Isothiocyanate, Chengsen Xue, Hilda A. Pasolli, Irene Piscopo, Daniel J. Gros, Christina Liu, Yamei Chen, Jen Wei Chiao

NYMC Faculty Publications

BACKGROUND: Phenethyl isothiocyanate (PEITC), present naturally in cruciferous vegetables, is a chemopreventive agent. It blocks initiation and post-initiation progression of carcinogenesis. Mechanism study in human prostate cancer cells revealed that PEITC is a dual inhibitor of aberrant DNA hypermethylation and histone deacetylases, reactivating silenced genes and regulating the androgen-mediated growth of tumor cells. The identity of the cellular organelle that initially interacts with PEITC has not been fully described. METHODS: Human prostate cancer LNCaP cells were exposed to PEITC and the effects on cellular fine structure examined by transmission electron microscopic studies. Alteration of mitochondrial membrane potential and cytochrome c …


Disruption Of Mutated Braf Signaling Modulates Thyroid Cancer Phenotype, Elyse K. Hanly, Shilpi Rajoria, Zbigniew Darzynkiewicz, Hong Zhao, Robert Suriano, Neha Tuli, Andrea L. George, Robert Bednarczyk, Edward J. Shin, Jan Geliebter, Raj K. Tiwari Mar 2014

Disruption Of Mutated Braf Signaling Modulates Thyroid Cancer Phenotype, Elyse K. Hanly, Shilpi Rajoria, Zbigniew Darzynkiewicz, Hong Zhao, Robert Suriano, Neha Tuli, Andrea L. George, Robert Bednarczyk, Edward J. Shin, Jan Geliebter, Raj K. Tiwari

NYMC Faculty Publications

BACKGROUND: Thyroid cancer is the most common endocrine-related cancer in the United States and its incidence is rising rapidly. Since among various genetic lesions identified in thyroid cancer, the BRAFV600E mutation is found in 50% of papillary thyroid cancers and 25% of anaplastic thyroid cancers, this mutation provides an opportunity for targeted drug therapy. Our laboratory evaluated cellular phenotypic effects in response to treatment with PLX4032, a BRAFV600E-specific inhibitor, in normal BRAF-wild-type thyroid cells and in BRAFV600E-positive papillary thyroid cancer cells. METHODS: Normal BRAF-wild-type thyroid cells and BRAFV600E-mutated papillary thyroid cancer cells were subjected to proliferation assays and analyzed for …


The Nature And The Degree Of The Relationship Between Chronic Absenteeism And Student Achievement In A Large Metropolitan School District And A Small School District In Florida, Nancy C. Kline Mar 2014

The Nature And The Degree Of The Relationship Between Chronic Absenteeism And Student Achievement In A Large Metropolitan School District And A Small School District In Florida, Nancy C. Kline

Graduate Student Dissertations, Theses, Capstones, and Portfolios

The Bring It 180 study provides insight and awareness into the importance of student attendance and its influence on student achievement. This study examines the nature and degree of the relationship between chronic absenteeism and academic proficiencies. The research findings identify meaningful correlations between attendance and student achievement in two Florida school districts.


Benedetti, Robert, Oral History Interview, Jon Schamber Mar 2014

Benedetti, Robert, Oral History Interview, Jon Schamber

Emeriti Society Oral History Collection

Dean, College of the Pacific and Executive Director, Jacoby Center (1989-2013). Topics include: Budget challenges 1990s, General Education reform, evolution of citizen leader concept, Atchley and DeRosa administrations, Midtown Magnolia Project, Stockton Speaks, More Votes that Count research project.


2014 March 25, Faculty Senate Minutes, State University Of New York At Cortland Mar 2014

2014 March 25, Faculty Senate Minutes, State University Of New York At Cortland

Minutes

Faculty Senate Minutes No. 11, March 25, 2014


Putin And Ukraine Mar 2014

Putin And Ukraine

News Releases

No abstract provided.


Letters To Grandma: A Comparison Of Generational Perspectives Of Women's Growth As Higher Education Faculty, Elyn Mcreynolds Palmer Mar 2014

Letters To Grandma: A Comparison Of Generational Perspectives Of Women's Growth As Higher Education Faculty, Elyn Mcreynolds Palmer

The Qualitative Report

This ethnographic compilation is the result of a course exercise in qualitative research. A current student of Texas Tech University interviewed an 87-yearold faculty member from the 1950s, comparing her experiences to those of the author in similar, present-day academic environments. The author developed the format of the paper as letters between a young faculty member and her experienced grandmother. Results of the study reflect many similarities between the experiences of past female faculty members and female faculty of today; the exercise does convey, however, many advances for women in the academic culture as well. Finally, the recorded experiences of …


Faculty Attitudes Towards Integrating Technology And Innovation, Colleen Marzilli, Julie Delello, Shelly Marmion, Rochell Mcwhorter Mar 2014

Faculty Attitudes Towards Integrating Technology And Innovation, Colleen Marzilli, Julie Delello, Shelly Marmion, Rochell Mcwhorter

Nursing Faculty Publications and Presentations

Technological innovation is an important aspect of teaching and learning in the 21st century. This article examines faculty attitudes toward technology use in the classroom at one regional public university in the United States. Building on a faculty-led initiative to develop a Community of Practice for improving education, this study used a mixed-method approach of a faculty-developed, electronic survey to assess this topic. Findings from 72 faculty members revealed an overall positive stance toward technology in the classroom and the average faculty member utilized about six technology tools in their courses. The opportunities, barriers and future uses for technologies in …


Angiotensin Ii Stimulates Basolateral 50-Ps K Channels In The Thick Ascending Limb, Mingxiao Wang, Haiyan Luan, Peng Wu, Lili Fan, Lijun Wang, Xinpeng Duan, Dandan Zhang, Wen-Hui Wang, Ruimin Gu Mar 2014

Angiotensin Ii Stimulates Basolateral 50-Ps K Channels In The Thick Ascending Limb, Mingxiao Wang, Haiyan Luan, Peng Wu, Lili Fan, Lijun Wang, Xinpeng Duan, Dandan Zhang, Wen-Hui Wang, Ruimin Gu

NYMC Faculty Publications

We used the patch-clamp technique to examine the effect of angiotensin II (ANG II) on the basolateral K channels in the thick ascending limb (TAL) of the rat kidney. Application of ANG II increased the channel activity and the current amplitude of the basolateral 50-pS K channel. The stimulatory effect of ANG II on the K channels was completely abolished by losartan, an inhibitor of type 1 angiotensin receptor (AT1R), but not by PD123319, an AT2R antagonist. Moreover, inhibition of phospholipase C (PLC) and protein kinase C (PKC) also abrogated the stimulatory effect of ANG II on the basolateral K …


Nfat5 Is Protective Against Ischemic Acute Kidney Injury, Shoujin Hao, Lars Bellner, Hong Zhao, Brian B. Ratliff, Zbigniew Darzynkiewicz, Carlos P. Vio, Nicholas R. Ferreri Mar 2014

Nfat5 Is Protective Against Ischemic Acute Kidney Injury, Shoujin Hao, Lars Bellner, Hong Zhao, Brian B. Ratliff, Zbigniew Darzynkiewicz, Carlos P. Vio, Nicholas R. Ferreri

NYMC Faculty Publications

NFAT5 is a transcription factor that protects the kidney from hypertonic stress and also is activated by hypoxia. We hypothesized that NFAT5 mitigates the extent of renal damage induced by ischemia-reperfusion injury (IRI). Mice were subjected to IRI by unilateral clamping of the left renal pedicle for 30 minutes followed by reperfusion. After 3 hours of reperfusion, the level of NFAT5 mRNA was similar in contralateral and clamped kidneys. However, after 48 hours, NFAT5 mRNA accumulation increased ≈3-fold in both outer medulla and medullary thick ascending limb tubules. NFAT1 levels were elevated at 3 hours but did not increase further …


Stress Management: Corpus-Based Insights Into Vernacular Interpretations Of "Stress", Laurel Smith Stvan Feb 2014

Stress Management: Corpus-Based Insights Into Vernacular Interpretations Of "Stress", Laurel Smith Stvan

Linguistics & TESOL Faculty Publications & Presentations - Archive

Examination of the term stress in naturally occurring vernacular prose provides evidence of three separate senses being conflated. A corpus analysis of 818 instances of stress from non-academic texts in the Corpus of Contemporary American English (COCA) and the Corpus of American Discourses on Health (CADOH) shows a negative prosody for stress, which is portrayed variously as a source outside the body, a physical symptom within the body and an emotional state. The data show that contemporary speakers intermingle the three senses, making more difficult a discussion between doctors and patients of ways to ‘reduce stress’, when stress might be …


Dehydroepiandrosterone Promotes Pulmonary Artery Relaxation By Nadph Oxidation-Elicited Subunit Dimerization Of Protein Kinase G 1Α, Dhara Patel, Sharath Kandhi, Melissa Kelly, Boon Hwa Neo, Michael S. Wolin Feb 2014

Dehydroepiandrosterone Promotes Pulmonary Artery Relaxation By Nadph Oxidation-Elicited Subunit Dimerization Of Protein Kinase G 1Α, Dhara Patel, Sharath Kandhi, Melissa Kelly, Boon Hwa Neo, Michael S. Wolin

NYMC Faculty Publications

The activity of glucose-6-phosphate dehydrogenase (G6PD) controls a vascular smooth muscle relaxing mechanism promoted by the oxidation of cytosolic NADPH, which has been associated with activation of the 1α form of protein kinase G (PKG-1α) by a thiol oxidation-elicited subunit dimerization. This PKG-1α-activation mechanism appears to contribute to responses of isolated endothelium-removed bovine pulmonary arteries (BPA) elicited by peroxide, cytosolic NADPH oxidation resulting from G6PD inhibition, and hypoxia. Dehydroepiandrosterone (DHEA) is a steroid hormone with pulmonary vasodilator activity, which has beneficial effects in treating pulmonary hypertension. Because multiple mechanisms have been suggested for the vascular effects of DHEA and one …


2014 February 4, Faculty Senate Minutes, State University Of New York At Cortland Feb 2014

2014 February 4, Faculty Senate Minutes, State University Of New York At Cortland

Minutes

Faculty Senate Minutes No. 8, February 4, 2014


Utility Of Serodiagnostics Designed For Use In The United States For Detection Of Lyme Borreliosis Acquired In Europe And Vice Versa, Gary P. Wormser, Aimee T. Tang, Natasha R. Schimmoeller, Susan Bittker, Denise Cooper, Paul Visintainer, Maria E. Aguero-Rosenfeld, Katarina Ogrinc, Franc Strle, Gerold Stanek Feb 2014

Utility Of Serodiagnostics Designed For Use In The United States For Detection Of Lyme Borreliosis Acquired In Europe And Vice Versa, Gary P. Wormser, Aimee T. Tang, Natasha R. Schimmoeller, Susan Bittker, Denise Cooper, Paul Visintainer, Maria E. Aguero-Rosenfeld, Katarina Ogrinc, Franc Strle, Gerold Stanek

NYMC Faculty Publications

Although two-tier testing is standard practice in both the United States and Europe for the serologic diagnosis of Lyme borreliosis (LB), the test kits generally differ. The purpose of this study was to determine if the testing used in the United States will detect LB acquired in Europe and vice versa. Testing was performed on a convenience sample of archived sera from 40 LB patients from Austria and 39 from the United States, using first- and second-tier test kits from both the United States and Europe. The sensitivity of four first-tier tests from Europe and two first-tier tests from the …


Shelter From The Storm: Rekindling Research On Collective Bargaining And Representation Issues, William A. Herbert Jan 2014

Shelter From The Storm: Rekindling Research On Collective Bargaining And Representation Issues, William A. Herbert

Journal of Collective Bargaining in the Academy

The National Center for the Study of Collective Bargaining in Higher Education and the Professions (National Center) is a four-decade old institution that is supported by and located at Hunter College, City University of New York. The National Center was founded in the wake of the granting of collective bargaining rights by various states and localities to public employees including higher education faculty members and shortly after the National Labor Relations Board (NLRB) asserted jurisdiction over private institutions of higher education.

Consistent with its mission, the National Center intends to be an engine for rekindling, incubating and promoting research and …


Positive Collaboration: Beyond Labor Conflict And Labor Peace, Richard Boris Jan 2014

Positive Collaboration: Beyond Labor Conflict And Labor Peace, Richard Boris

Journal of Collective Bargaining in the Academy

Institutions of higher education collectively constitute a major economic concentration that ranks—by whatever measure: resources, budgets, endowments, employees, constituencies—among the major industries in the United States. The unionized academic U.S. workforce ranks sixth among organized labor. Yet, when compared to the top-tier manufacturing industries of steel or automobile or to national unions such as the UAW or the Teamsters, both the public institutions of higher education and their academic unions lack national visibility, lack influence on national debates, and, most tellingly, lack major successes in the quest for public monies. Health care, the environment, energy policies, and the current global …


Hauben, Paul, Oral History Interview, Roland Difranco Jan 2014

Hauben, Paul, Oral History Interview, Roland Difranco

Emeriti Society Oral History Collection

Professor of History (1969-1994). Topics include: Participation in I & I Program, successive General Education programs, College of the Pacific Dean’s office, student quality, faculty observation of the President and Regents.


An Evaluation Of Healthcare Information On The Internet: The Case Of Colorectal Cancer Prevention, Chia-Ching Chen, Tetsuji Yamada, John Smith Jan 2014

An Evaluation Of Healthcare Information On The Internet: The Case Of Colorectal Cancer Prevention, Chia-Ching Chen, Tetsuji Yamada, John Smith

NYMC Faculty Publications

Health information, provided through the Internet, has recently received attention from consumers and healthcare providers as an efficient method of motivating people to get screened for colorectal cancer (CRC). In this study, the primary purpose was to investigate the extent to which consumers were better educated about CRC screening information because of the information available on the Internet. Another purpose was to identify how better-informed consumers, with reliable and trustworthy health information, were enabled to make sound decisions regarding CRC screening. The data used in this study was taken from the 2003 Health Information National Trends Survey. People aged 55 …


Early-Life Seizures In Predisposing Neuronal Preconditioning: A Critical Review, Linda Friedman, Shirley Hu Jan 2014

Early-Life Seizures In Predisposing Neuronal Preconditioning: A Critical Review, Linda Friedman, Shirley Hu

NYMC Faculty Publications

Although seizures are known to be harmful, recent evidence indicates that they can also lead to adaptations that protect neurons from further insult. For example, a history of two episodes of status epilepticus during a critical period of early development can prolong the time period of resistance to hippocampal injury during the postnatal period. Neonatal seizures may lead to this neuroprotection via a preconditioning mechanism that could be attributed to attenuation of Ca(2+) currents, reduction of inflammation, and induction of survival signaling pathways. Understanding mechanisms underlying neuroprotective preconditioning may elucidate new therapeutic targets and improve outcomes and quality of life …


A Life Of Music Jan 2014

A Life Of Music

News Releases

No abstract provided.