Digital Commons Network^™

Maintaining Weight Loss In Obese Men With Prostate Cancer Following A Supervised Exercise And Nutrition Program—A Pilot Study, Rebekah L. Wilson, Dennis R. Taaffe, Robert U. Newton, Nicolas H. Hart, Philippa Lyons-Wall, Daniel A. Galvão

Research outputs 2014 to 2021

Supervised exercise and nutrition programs can mitigate or reverse androgen deprivation therapy (ADT) induced fat mass (FM) gain, lean mass (LM) loss, and impaired physical function. It is unclear whether these benefits are retained following transition to self-management. This study examined the effect of a home-based weight maintenance program on body composition and physical function in obese men with prostate cancer (PCa) on ADT following a 12-week supervised weight loss intervention. Eleven obese PCa patients (74 ± 5 years, 40.0 ± 4.9% body fat) on ADT ( > 6 months) com-pleted a 12-week self-managed home-based weight maintenance program consisting of 150 …

Associations Of Physical Activity And Exercise With Health-Related Outcomes In Patients With Melanoma During And After Treatment: A Systematic Review, Brendan J. Crosby, Pedro Lopez, Daniel A. Galvao, Robert U. Newton, Dennis Taaffe, Tarek M. Meniawy, Lydia Warburton, Muhammad A. Khattak, Elin S. Gray, Favil Singh

Research outputs 2014 to 2021

Purpose:

Although exercise medicine is recommended to counter treatment-related side-effects and improve health-related outcomes of patients affected by different cancers, no specific recommendations exist for patients with melanoma. As a result, we systematically examined the current evidence regarding the effects of physical activity and exercise on objectively-measured and patient-reported outcomes among patients with melanoma.

Methods:

Searches were conducted in PubMed, CINAHL, EMBASE, SPORTDiscus, and Web of Science databases. This review included published data involving physical activity or exercise and objectively-measured or patient-reported outcomes of patients with cutaneous melanoma. The quality of included studies was assessed using …

Usability, Acceptability, And Safety Analysis Of A Computer-Tailored Web-Based Exercise Intervention (Exerciseguide) For Individuals With Metastatic Prostate Cancer: Multi-Methods Laboratory-Based Study, Holly E. L. Evans, Cynthia C. Forbes, Daniel A. Galvão, Corneel Vandelanotte, Robert U. Newton, Gary Wittert, Suzanne Chambers, Andrew D. Vincent, Ganessan Kichenadasse, Danielle Girard, Nicholas Brook, Camille E. Short

Research outputs 2014 to 2021

Background:

Digital health interventions such as tailored websites are emerging as valuable tools to provide individualized exercise and behavioral change information for individuals diagnosed with cancer.

Objective:

The aim of this study is to investigate and iteratively refine the acceptability and usability of a web-based exercise intervention (ExerciseGuide) for men with metastatic prostate cancer and determine how well individuals can replicate the video-based exercise prescription.

Methods:

A laboratory-based multi-methods design was used, incorporating questionnaires, think-aloud tests, interviews, and movement screening among 11 men aged 63 to 82 years with metastatic prostate cancer. Overall, 9 participants were undergoing androgen deprivation therapy, …

Acceptability And Preliminary Efficacy Of A Web-And Telephone-Based Personalised Exercise Intervention For Individuals With Metastatic Prostate Cancer: The Exerciseguide Pilot Randomised Controlled Trial, Holly E. L. Evans, Daniel A. Galvão, Cynthia C. Forbes, Danielle Girard, Corneel Vandelanotte, Robert U. Newton, Andrew D. Vincent, Gary Wittert, Ganessan Kichenadasse, Suzanne Chambers, Nicholas Brook, Camille E. Short

Research outputs 2014 to 2021

Preliminary research has shown the effectiveness of supervised exercise-based interventions in alleviating sequela resulting from metastatic prostate cancer. However, many individuals encounter barriers that limit the uptake of face-to-face exercise. Technology-enabled interventions offer a distance-based alternative. This pilot study aimed to explore the acceptability, safety and preliminary efficacy of a web-based exercise intervention (ExerciseGuide) in individuals with metastatic prostate cancer. Forty participants (70.2 ± 8.5 years) with metastatic prostate cancer were randomised into the 8-week intervention (N = 20) or a wait-list control (N = 20). The intervention arm had access to a computer-tailored website, personalised exercise prescription and remote …

Exercise Capacity, Muscle Strength, Dyspnea, Physical Activity, And Quality Of Life Inpreoperative Patients With Lung Cancer, Gülşah Barği, Ece Baytok, Zeli̇ha Çeli̇k, Merve Şatir Türk, Ali̇ Çeli̇k, İsmai̇l Cüneyt Kurul, Meral Boşnak Güçlü

Turkish Journal of Medical Sciences

Background/aim: To detect the extent to which physical impairments are observed in patients with lung cancer awaiting lung surgery, exercise capacity, muscle strength, physical activity, dyspnea, and quality of life (QOL) were objectively compared between the patients and healthy individuals in current study. Materials and methods: Patients with lung cancer (n = 26) and healthy individuals (n = 21) were included. Exercise capacity, respiratory (maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP)) and quadriceps femoris muscle strength, physical activity, dyspnea and QOL were evaluated using 6-min walk test (6-MWT), a mouth pressure device, a hand-held dynamometer, a metabolic holter device, …

Effect Of Exercise On Blood Pressure And Body Mass Index In At-Risk Populations, Jared Crum, Victoria Patterson, Riley Jarvis

Williams Honors College, Honors Research Projects

Higher blood pressure and basal metabolic rate (BMI) are health problems in the United States (U.S.), but particularly in high risk minority populations, in part because of limited access to adequate resources to help themselves become healthier. This Honors Paper aimed to examine the effect of an exercise intervention on blood pressure and BMI in high risk minority populations. The honors project is a part of the Finding A Better You (FABU) project by College of Health Profession faculty Dr. Murrock, Dr. MacCracken, and Dr. Juvancic-Heltzel. The FABU project assessed at risk individuals (lower income older adults) in Summit County …

Impact Of Covid-19 On Ohio's National Parks Visitation, Ryan Grzeschik

Williams Honors College, Honors Research Projects

The COVID-19 pandemic has fundamentally changed the way in which society operates in order to get the novel disease under control. Businesses throughout the United States have had to close or reduce provided services, stay at home orders have secluded many people, and social distancing limits contact between others so many are turning to the parks system to cope with these changes. This study aims to find how the visitation of national parks in Ohio have been affected through the first six months of the pandemic. Visitation statistics were compared from March to August of 2020 to those same months …

Everyday Tips To Achieve A Healthy Weight, University Of New England Applied Nutrition Program

All Student-Created Educational Resources

This handout depicts six evidence-based practices to help overweight and obese individuals achieve a healthy weight. These tips are meant to be easily integrated into everyday life, and are backed by the CDC, USDA, and multiple scientific studies and reviews.

Vulnerable And Resilient Phenotypes In A Mouse Model Of Anorexia Nervosa, Jeff A. Beeler, Devry Mourra, Roseanna M. Zanca, Abigail Kalmbach, Celia Gellman, Benjamin Y. Klein, Rebecca Ravenelle, Peter Serrano, Holly Moore, Stephen Rayport, Susana Mingote, Nesha Burghard

Advanced Science Research Center

Background

Increased physical activity is a common feature of anorexia nervosa (AN). Although high activity levels are associated with greater risk of developing AN, particularly when combined with dieting, most individuals who diet and exercise maintain a healthy body weight. It is unclear why some individuals develop AN while most do not. A rodent model of resilience and vulnerability to AN would be valuable to research. Dopamine, which is believed to play a crucial role in AN, regulates both reward and activity and may modulate vulnerability.

Methods

Adolescent and young adult female C57BL/6N mice were tested in the activity-based anorexia …

Identifying Factors To Inform The Development Of Adaptive Interventions For Increasing Physical Activity Behavior Among People With Multiple Schlerosis, Yumi Kim

All ETDs from UAB

People with multiple sclerosis (MS) can benefit from physical activity, specifically exercise, for the management of disease symptoms, including walking impairments, fatigue, and depression, and improvements in quality of life. However, people with MS do not engage in adequate amounts of physical activity for the accrual of health benefits. Researchers have focused on the delivery of exercise training and behavioral interventions to improve levels of physical activity in MS. To date, there is an emerging body of research supporting the efficacy of these interventions for increasing and potentially sustaining physical activity behavior in people with MS. Yet, people with MS …

Lutein/Zeaxanthin Isomers Regulate Neurotrophic Factors And Synaptic Plasticity Intrained Rats, Cemal Orhan, Füsun Erten, Beşi̇r Er, Mehmet Tuzcu, Nurhan Şahi̇n, Öznur Ece Durmaz Kurşun, Vijaya Juturu, Kazi̇m Şahi̇n

Turkish Journal of Medical Sciences

Background/aim: This study was conducted to elucidate the effects of lutein/zeaxanthin isomers (L/Zi) on lipid metabolism, oxidative stress, NF-ΚB/Nrf2 pathways, and synaptic plasticity proteins in trained rats. Materials and methods: Wistar rats were distributed into four groups: 1) control, 2) L/Zi: rats received L/Zi at the dose of 100 mg/kg by oral gavage, 3) exercise, 4) exercise+L/Zi: rats exercised and received L/Zi (100 mg/kg) by oral gavage. The duration of the study was eight weeks. Results: Exercise combined with L/Zi reduced lipid peroxidation and improved antioxidant enzyme activities of muscle and cerebral cortex in rats (p < 0.001). In the Exercise + L/Zi group, muscle and cerebral cortex Nrf2 and HO-1 levels increased, while NF-ΚB levels decreased (p

Effects Of Intracerebroventricularly Administered Opioid Peptide Antagonistson Tissue Glycogen Levels In Rats After Exercise, Ayşe Şebnem İlhan, Şevi̇n Güney, Si̇bel Di̇ncer

Turkish Journal of Medical Sciences

Background/aim: Physical exercise is a state of physiological stress that requires adaptation of the organism to physical activity. Glycogen is an important and essential energy source for muscle contraction. Skeletal muscle and liver are two important glycogen stores, and the energy required to maintain exercise in rodents are provided by destruction of this glycogen depot. In this study, the effects of endogenous opioid peptide antagonism at the central nervous system level on tissue glycogen content after exhaustive exercise were investigated. Materials and methods: Rats had intracerebroventricularly (icv) received nonspecific opioid peptide receptor antagonist, naloxone (50 μ/10 μL in saline) and …

Metabolomics And Lipidomics: Expanding The Molecular Landscape Of Exercise Biology, Mehdi R. Belhaj, Nathan G. Lawler, Nolan J. Hoffman

Research outputs 2014 to 2021

Dynamic changes in circulating and tissue metabolites and lipids occur in response to exercise-induced cellular and whole-body energy demands to maintain metabolic homeostasis. The metabolome and lipidome in a given biological system provides a molecular snapshot of these rapid and complex metabolic perturbations. The application of metabolomics and lipidomics to map the metabolic responses to an acute bout of aerobic/endurance or resistance exercise has dramatically expanded over the past decade thanks to major analytical advancements, with most exercise-related studies to date focused on analyzing human biofluids and tissues. Experimental and analytical con-siderations, as well as complementary studies using animal model …

Diabetes Training Camp: A Brief Intervention To Improve Self-Management And Physical Activity In Adults With Type 1 Diabetes, David Charny

PCOM Psychology Dissertations

Type 1 Diabetes (T1D) is less common than Type 2 Diabetes (T2D); however, its growing incidence, chronic prognosis, and increased self-management burden, produce unique psychosocial challenges for this population. Specifically, these individuals are atrisk for poor diabetes self-efficacy, and poor glycemic control, which can contribute to diabetes-specific mood alterations, or diabetes distress (DD), and an overall reduction in diabetes-specific health-related quality of life. This study evaluated the effectiveness of the Diabetes Training Camp (DTC) 1-week intervention in mitigating psychosocial distress utilizing a repeated measures design to evaluate the impact of participation on measures of DD, diabetes quality of life (DQOL) …

Using Exercise And Nutrition To Alter Fat And Lean Mass In Men With Prostate Cancer Receiving Androgen Deprivation Therapy: A Narrative Review, Rebekah L. Wilson, Dennis R. Taaffe, Robert U. Newton, Nicolas H. Hart, Philippa Lyons-Wall, Daniel A. Galvao

Research outputs 2014 to 2021

Fat mass (FM) gain and lean mass (LM) loss are common side effects for patients with prostate cancer receiving androgen deprivation therapy (ADT). Excess FM has been associated with an increased risk of developing obesity-related comorbidities, exacerbating prostate cancer progression, and all-cause and cancer-specific mortality. LM is the predominant contributor to resting metabolic rate, with any loss impacting long-term weight management as well as physical function. Therefore, reducing FM and preserving LM may improve patient-reported outcomes, risk of disease progression, and ameliorate comorbidity development. In ADT-treated patients, exercise and nutrition programs can lead to improvements in quality of life and …

Exercise Medicine In The Management Of Pancreatic Cancer: A Systematic Review, Hao Luo, Daniel A. Galvão, Robert U. Newton, Pedro Lopez Da Cruz, Colin Tang, Ciaran M. Fairman, Nigel Spry, Dennis R. Taaffe

Research outputs 2014 to 2021

The aim of this study was to examine the health-related effects of exercise in patients with pancreatic cancer (PanCa) through a systematic review of current evidence. Studies were obtained through searching PubMed, Web of Science, PsycINFO, Embase, CINAHL Plus, and Cochrane Library databases with additional hand searches. All intervention-based studies were included if it involved (1) adult patients with PanCa, (2) exercise training, and (3) findings in quality of life, cancer-related fatigue, psychological distress, and physical function. The review protocol was registered in PROSPERO: CRD42020154684. Seven trials described in 9 publications were included consisting of 201 patients with early-stage and …

Prevalence And Factors Associated With Nafld Detected By Vibration Controlled Transient Elastography Among Us Adults: Results From Nhanes 2017–2018, Xiaotao Zhang, Natalia I Heredia, Maya Balakrishnan, Aaron P Thrift

Faculty, Staff and Students Publications

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is increasingly common in the adult population. In the United States, the overall burden of NAFLD is unknown due to challenges with population-level NAFLD detection. The purpose of this study was to estimate prevalence of NAFLD and significant NAFLD fibrosis and identify factors associated with them in the U.S.

METHODS: Data came from the 2017-2018 cycle of National Health and Nutrition Examination Survey. We defined NAFLD by controlled attenuation parameter (CAP) scores of ≥248 dB/m in absence of excessive alcohol use and viral hepatitis. We defined significant fibrosis as Vibration controlled transient elastography (VCTE) …

The Effects Of Exercise On Breastmilk Composition And Supply: A Critical Literature Review, Jewell Mcroy

Masters Theses, 2020-current

It is well established that breastfeeding provides dual benefits to both the mother and the infant and is the preferred method of providing nutrients to infants essential for growth and development. Participating in regular physical exercise is also well-supported by research to be beneficial to one’s overall health and quality of life. Currently there are no physical activity guidelines developed for women who are postpartum and breastfeeding. An online database search was conducted; three articles met the inclusion criteria and were included within the review. Studies were included if there were direct measures of human breastmilk composition, supply/volume, and included …

Exercise To Improve Cancer-Related Fatigue, Jennifer Watson

MSN Capstone Projects

For the average patient, medical professionals typically recommend exercise to enhance the health of their patients in multiple ways. Oncology patients, however, often have different issues that the treating physicians are more concerned about, so physical activity gets placed on the back burner. The need for exercise in oncology patients is certainly a decision that should be part of an individualized treatment plan, but it is reasonable to believe that most of these patients will benefit from participating in an exercise program. With the high demanding need to decrease chemotherapy side effects and improve lives of those undergoing it, this …

Has The Pandemic Brought About A Healthier Lifestyle Among Adults?, Amirul Roslee

Introduction to Research Methods RSCH 202

This study is the first in Singapore to examine how the lockdown had an impact on lifestyle habits among adults above 18 years old in Singapore. The results were collected through an online survey consisting of 18 questions. Linear Regression is used to find the relation between healthier people and the variables. The data analysis determined whether significant differences exist between essential workers and non-essential workers. The proposed research will aim to gain a deeper understanding of the lifestyle changes affected by the lockdown mainly with regards to exercise, sleeping habits, and mode of working.

2020 Who Guidelines On Physical Activity And Sedentary Behaviour For Children And Adolescents Aged 5–17 Years: Summary Of The Evidence, Jean Philippe Chaput, Juana Willumsen, Fiona Bull, Roger Chou, Ulf Ekelund, Joseph Firth, Russell Jago, Francisco B. Ortega, Peter T. Katzmarzyk

Population and Public Health Science Faculty Publications

Background: The World Health Organization (WHO) released in 2020 updated global guidelines on physical activity and sedentary behaviour for children, adolescents, adults, older adults and sub-populations such as pregnant and postpartum women and those living with chronic conditions or disabilities. Objective: To summarize the evidence on the associations between physical activity, sedentary behaviour, and health-related outcomes used to inform the 2020 WHO guidelines on physical activity and sedentary behaviour for children and adolescents aged 5–17 years. Methods: The update of the WHO guideline recommendations for children and adolescents utilized and systematically updated the evidence syntheses on physical activity and sedentary …

New Global Guidelines On Sedentary Behaviour And Health For Adults: Broadening The Behavioural Targets, Paddy C. Dempsey, Stuart J.H. Biddle, Matthew P. Buman, Sebastien Chastin, Ulf Ekelund, Christine M. Friedenreich, Peter T. Katzmarzyk, Michael F. Leitzmann, Emmanuel Stamatakis, Hidde P. Van Der Ploeg, Juana Willumsen, Fiona Bull

Population and Public Health Science Faculty Publications

Background: In 2018, the World Health Organisation (WHO) commenced a program of work to update the 2010 Global Recommendations on Physical Activity for Health, for the first-time providing population-based guidelines on sedentary behaviour. This paper briefly summarizes and highlights the scientific evidence behind the new sedentary behaviour guidelines for all adults and discusses its strengths and limitations, including evidence gaps/research needs and potential implications for public health practice. Methods: An overview of the scope and methods used to update the evidence is provided, along with quality assessment and grading methods for the eligible new systematic reviews. The literature search update …

Early Physical Activity Adoption Predicts Longer-Term Physical Activity Among Individuals Inactive At Baseline, Jessica L. Unick, Michael P. Walkup, Michael E. Miller, John W. Apolzan, Peter H. Brubaker, Mace Coday, James O. Hill, John M. Jakicic, Roeland J.W. Middelbeek, Delia West, Rena R. Wing

Clinical Research Faculty Publications

Background: To examine the relationship between early physical activity (PA) adoption (2, 3, and 4 mo) and longer-term PA adherence (1 y) among individuals who were inactive at baseline and received a lifestyle intervention. Methods: Participants (n = 637) received weekly behavioral weight loss sessions, calorie reduction, and PA goals (50.175 min/wk progression). PA was assessed via self-reported measures at baseline, months 2 to 4, and 1 year. Results: PA at months 2 to 4 was significantly correlated with PA at 1 year (rs = .29..35, P < .01). At all early time points, those failing to meet the prescribed PA goal (early nonadopters) engaged in significantly less PA at 1 year than those meeting the early PA goal (initial adopters). For example, using 2-month criteria, initial adopters engaged in 108.3 minutes per week more at 1 year compared with early nonadopters (P < .01) and had 2.8 times the odds (95% confidence interval, 1.9.4.2) of meeting the 1-year PA goal (≥175 min/wk, P < .01). Conclusions: Failure to achieve PA goals at 2, 3, or 4 months results in less overall PA at 1 year. Thus, PA observed as early as month 2 may be a useful indicator for identifying at-risk individuals who may benefit from more intensive PA intervention strategies.

Practices Of Athletic Trainers Using Weight Charts To Determine Hydration Status And Fluid-Intervention Strategies, Jeremy M. Eith, Clint R. Haggard, Dawn M. Emerson, Susan Yeargin Ph.D., Atc

Faculty Publications

Context

Determining an athlete's hydration status allows hydration-related concerns to be identified before significant medical or performance concerns arise. Weight charts are an accurate measure of hydration status changes, yet their clinical use by athletic trainers (ATs) is unknown.

Objective

To investigate ATs' use of weight charts in athletic settings and describe their subsequent clinical decisions.

Design

Cross-sectional survey.

Setting

High schools and National Collegiate Athletic Association Divisions I, II, III and National Association Intercollegiate Athletics colleges.

Patients or Other Participants

A total of 354 ATs (men = 162, women = 175; 17 respondents did not answer the demographic questions) …

Practices Of Athletic Trainers Using Weight Charts To Determine Hydration Status And Fluid-Intervention Strategies, Jeremy M. Eith, Clint R. Haggard, Dawn M. Emerson, Susan W. Yeargin Ph.D., Atc

Faculty Publications

Context

Determining an athlete's hydration status allows hydration-related concerns to be identified before significant medical or performance concerns arise. Weight charts are an accurate measure of hydration status changes, yet their clinical use by athletic trainers (ATs) is unknown.

Objective

To investigate ATs' use of weight charts in athletic settings and describe their subsequent clinical decisions.

Design

Cross-sectional survey.

Setting

High schools and National Collegiate Athletic Association Divisions I, II, III and National Association Intercollegiate Athletics colleges.

Patients or Other Participants

A total of 354 ATs (men = 162, women = 175; 17 respondents did not answer the demographic questions) …

Diet And Exercise: What To Eat And When, Brittany Allman

Diet, Food, Exercise, and Nutrition (D-FEND)

Learning Objectives:

Define nutrient timing

Understand the importance of nutrient timing

Understand the different types of carbohydrates

Understand how eating patterns can affect sleep

Perceived Benefits And Barriers To Participation In Exercise Among Jordanian University Students, Khaldoun Hamdan

Al-Balqa Journal for Research and Studies البلقاء للبحوث والدراسات

Insufficient physical activity is a risk factor for many non-communicable diseases, therefore; the purpose of this study is to examine university students’ perceived exercise benefits and barriers. This cross-sectional descriptive study used Exercise Benefits/Barriers Scale to examine perceived benefits and barriers to exercise among a convenience sample of 517 university students in Jordan. Participants reported significantly higher perceived barriers to exercise than perceived benefits from exercise. The most important perceived barrier to exercise was “I am too embarrassed to exercise”. Moreover, “I will live longer if I exercise” and “exercising increases being accepted by others” were the most important perceived …

Strengths, Challenges, And Opportunities For Physical Activity Promotion In The Century-Old National Cooperative Extension System, Samantha M. Harden, Laura Balis, Thomas Strayer Iii, Nikki Prosch, Breanne Carlson, Anne Lindsay, Paul A. Estabrooks, David A. Dzewaltowski, Katherine B. Gunter

Journal of Human Sciences and Extension

The need for physical activity promotion is ubiquitous, and offering physical activity interventions in community settings may reach people where they live, work, and play. Reaching people and providing evidence-based programming is exactly what the Cooperative Extension System has accomplished over the last century. In 2014, federal policy brought physical activity promotion into the mission of Extension. Although this policy marks the beginning of concerted efforts for physical activity promotion, several states have had strong success in this area. Borrowing from these efforts, this paper reports strengths, challenges, and opportunities for physical activity promotion in Extension.

Exercise For Weight Loss: Further Evaluating Energy Compensation With Exercise, Kyle D. Flack, Harry M. Hays, Jack Moreland, Douglas E. Long

Dietetics and Human Nutrition Faculty Publications

PURPOSE: This study assessed how individuals compensate for energy expended during a 12-wk aerobic exercise intervention, elucidating potential mechanisms and the role exercise dose plays in the compensatory response.

PARTICIPANTS AND DESIGN: Three-arm, randomized controlled trial among sedentary adults age 18 to 40 yr, body mass index of 25 to 35. Groups included six exercise sessions per week, two sessions per week, and sedentary control.

METHODS: Rate of exercise energy expenditure was calculated from a graded exercise test averaged across five heart rate zones. Energy compensation was calculated as the difference between expected weight loss (based on exercise energy expenditure) …

Nutrition, Exercise, And Mental Health, Jamie Baum

Diet, Food, Exercise, and Nutrition (D-FEND)

Understand factors that can impact our mental health

Understand how certain foods can benefit our mental health

Understand how exercise can benefit our mental health