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A Study Of Dietary Patterns Derived By Cluster Analysis And Their Association With Metabolic Dysfunction-Associated Steatotic Liver Disease Severity Among Hispanic Patients, Xiaotao Zhang, Carrie R Daniel, Valeria Soltero, Ximena Vargas, Shilpa Jain, Fasiha Kanwal, Aaron P Thrift, Maya Balakrishnan

Faculty, Staff and Student Publications

Introduction: Diet is a modifiable metabolic dysfunction-associated steatotic liver disease (MASLD) risk factor, but few studies have been conducted among Hispanic patients, despite the fact that MASLD prevalence and severity are highest among this ethnic subgroup. We aimed to identify prevalent dietary patterns among Hispanic patients using cluster analysis and to investigate associations with MASLD severity.

Methods: This cross-sectional analysis included 421 Harris County MASLD Cohort participants who self-reported Hispanic ethnicity and completed baseline food frequency questionnaires. All included patients had MASLD, diagnosed per standard clinical criteria. K-means analysis was used to identify clusters of patients sharing similar dietary habits. …

Reply To Ayoub-Charette Et Al Lack Of Biological Plausibility And Major Methodological Issues Cast Doubt On The Association Between Aspartame And Autism Comment On "Fowler Et Al Daily Early-Life Exposures To Diet Soda And Aspartame Are Associated With Autism In Males: A Case-Control Study, Sharon Parten Fowler, David Gimeno Ruiz De Porras, Michael D Swartz, Paula Stigler Granados, Lynne Parsons Heilbrun, Raymond F Palmer

Faculty, Staff and Student Publications

Thank you for the opportunity to respond to the concerns raised by Ayoub-Charette et al [...].

Self-Reported Dietary Habits And Barriers Among Rotc Cadets, Sarah E. Johnson, Adriana Gil, Broderick Dickerson, James L. Lilly, Ryan J. Sowinski, Steven E. Martin, Drew E. Gonzalez

International Journal of Exercise Science: Conference Proceedings

Reserve Officer Training Corps (ROTC) cadets' highly demanding lifestyle may negatively impact health and performance. Reports also suggest they are at risk for poor nutrition, i.e., low energy availability or not meeting Military Dietary Reference Intakes. Still, there are limited data on the barriers to proper nutrition and eating habits among ROTC cadets. PURPOSE: This study aimed to investigate the dietary habits of ROTC cadets and the factors or barriers influencing them. METHODS: Cross-sectional data were obtained from 173 ROTC cadets about nutritional habits, factors, and barriers via validated paper-based questionnaires including; the Perceived Barriers to Healthy Eating, …

Food And Mood: The Correlation Between Vitamin B12 And Folate Intake And Depression, Jana Soucar, Hawley Almstedt

Honors Thesis

Vitamin B12 is an essential nutrient that metabolizes homocysteine, which is a potentially neurotoxic molecule when in excess. Folate is a B vitamin that is essential to the production of norepinephrine, serotonin, and dopamine in the brain. Studies show that a deficiency in vitamin B12, as well as folate, may be associated with mental health conditions. Additionally, the prevalence of depression is higher in college students than other demographic populations. PURPOSE: The purpose of this study was to investigate a correlation between vitamin B12 and folate intake with signs and symptoms of depression in college students. METHODS: This …

Study Design And Methods: Us Study To Protect Brain Health Through Lifestyle Intervention To Reduce Risk (Us Pointer), Laura D Baker, Heather M Snyder, Mark A Espeland, Rachel A Whitmer, Miia Kivipelto, Nancy Woolard, Jeffrey Katula, Kathryn V Papp, Jennifer Ventrelle, Sarah Graef, Marcus A Hill, Scott Rushing, Julia Spell, Laura Lovato, Deborah Felton, Benjamin J Williams, Mina Ghadimi Nouran, Rema Raman, Tiia Ngandu, Alina Solomon, Sharon Wilmoth, Maryjo L Cleveland, Jeff D Williamson, Katherine L Lambert, Sarah Tomaszewski Farias, Claire E Day, Christy C Tangney, Darren R Gitelman, Olivia Matongo, Terrianne Reynolds, Valory N Pavlik, Melissa M Yu, Ashley S Alexander, Richard Elbein, Ann Marie Mcdonald, Stephen Salloway, Rena R Wing, Susan Antkowiak, Martha Clare Morris, Maria C Carrillo

Faculty, Staff and Students Publications

INTRODUCTION: The U.S. study to protect brain health through lifestyle intervention to reduce risk (U.S. POINTER) is conducted to confirm and expand the results of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) in Americans.

METHODS: U.S. POINTER was planned as a 2-year randomized controlled trial of two lifestyle interventions in 2000 older adults at risk for dementia due to well-established factors. The primary outcome is a global cognition composite that permits harmonization with FINGER.

RESULTS: U.S. POINTER is centrally coordinated and conducted at five clinical sites (ClinicalTrials.gov: NCT03688126). Outcomes assessments are completed at baseline and …

Dietary Folate And Cofactors Accelerate Age-Dependent P16 Epimutation To Promote Intestinal Tumorigenesis, Li Yang, Robert C Peery, Leah M Farmer, Xia Gao, Yiqun Zhang, Chad J Creighton, Lanjing Zhang, Lanlan Shen

Faculty, Staff and Students Publications

The extent to which non-genetic environmental factors, such as diet, contribute to carcinogenesis has been long debated. One potential mechanism for the effects of environmental factors is through epigenetic modifications that affect gene expression without changing the underlying DNA sequence. However, the functional cooperation between dietary factors and cancer-causing epigenetic regulation is largely unknown. Here, we use a mouse model of age-dependent p16 epimutation, in which the p16 gene activity is directly controlled by promoter DNA methylation. We show p16 epimutation is modulated by folate and cofactors in dietary supplementation, which leads to increased colon cancer risk. Importantly, our findings …

Pilot Implementation Of A Nutrition-Focused Community-Health-Worker Intervention Among Formerly Chronically Homeless Adults In Permanent Supportive Housing, Jane E Hamilton, Diana C Guevara, Sara F Steinfeld, Raina Jose, Farrah Hmaidan, Sarah Simmons, Calvin W Wong, Clara Smith, Eva Thibaudeau-Graczyk, Shreela V Sharma

Faculty, Staff and Student Publications

Food insecurity is a known health equity threat for formerly chronically homeless populations even after they transition into permanent housing. This project utilized a human-centered design methodology to plan and implement a nutrition-focused community-health-worker (CHW) intervention in permanent supportive housing (PSH). The project aimed to increase access to healthy foods, improve nutritional literacy, healthy cooking/eating practices, and build community/social connectedness among 140 PSH residents. Validated food-security screening conducted by CHWs identified low or very low food security among 64% of 83 residents who completed the baseline survey, which is similar to rates found in a previous study among formerly homeless …

Study Of Vitamin D Deficiency Among Menopausal Women In Basrah City, Weaam Al-Mahfooth

Iraqi National Journal of Medicine

Background: Vitamin D deficiency is well-recognized worldwide. It is common in older adults, especially in women. Vitamin D deficiency is the most underdiagnosed medical condition in menopausal women. There are few epidemiological studies on the vitamin D status of menopausal women in Basra City, Iraq.  Aim: The aim of the study is to determine the prevalence of vitamin D deficiency among menopausal women in Basra City and its correlation with various factors that lead to vitamin D deficiency in menopausal women.  Methods: A prospective cross-sectional study was conducted on 200 menopausal women in the age group 46–65 years attending the …

Regional Variability In The Prevalence Of Food Insecurity And Diet Quality Among United States Children, Jayna M Dave, Tzuan A Chen, Alexandra N Castro, Mamie White, Elizabeth A Onugha, Sloane Zimmerman, Debbe Thompson

Children’s Nutrition Research Center Staff Publications

Understanding the association between food security status (FSS) and diet quality in children is crucial. This study investigated regional variability in FSS, participation in the federal nutrition assistance program (FNAP), and diet quality among US children. National Health and Nutrition Examination Survey (NHANES) data from 2013 to 2016 were analyzed. The association between FSS, FNAP participation, and diet quality (Healthy Eating Index—HEI-2015) was assessed using multiple linear/logistic regression models. The sample included 6403 children (mean age: 7.5 years; 51% male; 33% Hispanic). Within the sample, 13% reported child food insecurity, and 30% reported household food insecurity. Additionally, 90% participated in …

"Once I Take That One Bite": The Consideration Of Harm Reduction As A Strategy To Support Dietary Change For Patients With Diabetes, Alexzandra Gentsch, Megan Reed, Amy Cunningham, Anna Marie Chang, Stephanie Kahn, Danielle Kovalsky, Amanda Doty, Geoffrey Mills, Judd Hollander, Kristin Rising

College of Population Health Faculty Papers

BACKGROUND: Despite well-established guidelines to treat diabetes, many people with diabetes struggle to manage their disease. For many, this struggle is related to challenges achieving nutrition-related lifestyle changes. We examined how people with diabetes describe barriers to maintaining a healthy diet and considered the benefits of using a harm reduction approach to assist patients to achieve nutrition-related goals.

METHODS: This is a secondary analysis of 89 interviews conducted with adults who had type 1 or type 2 diabetes. Interviews were analyzed using a content analysis approach. Themes regarding food or diet were initially captured in a "food" node. Data in …

Incorporation Of Nutrition Education With Medication Injection To Sustain Weight Loss, Julia Calvelo

Nursing | Senior Theses

Background: Obesity is a widespread occurrence linked to comorbidities. Weight loss and maintenance is crucial to sustain existing health conditions and reduce risk of chronic diseases.

Lack of maintained weight loss is associated with poor education on nutrition, diet, and physical activity literacy. Objective: The purpose of this quantitative experimental study is to determine the efficacy of nutrition education among medication injection to sustain weight loss throughout treatment. It aims to promote comprehension of the aspects of nutrition, dietary habits, and physical education to not only sustain weight loss, but to understand the significance of how these elements contribute to …

The Impact Of Fish Intake (Primarily The Omega-3 Fatty Acid Concentration) On Cognitive Decline: A Systematic Review, Emma Martin

2024 Awards for Excellence in Student Research and Creative Activity - Documents

The purpose of this systematic review is to explore the effect of fish intake on cognitive decline. Previous studies on fish intake and cognitive decline have produced both supportive results and results that yield ineffectiveness. This review focuses primarily on omega 3 concentration from fish intake and its influence on mild cognitive impairment. Using several search engines, studies were selected by searching “fish intake and cognitive decline”. Inclusion criteria consisted of individuals diagnosed with MCI, intervention of fish intake, and omega 3 fatty acid concentration and cognitive function exams conducted at baseline and throughout the study. Nine out of the …

Nurse's Knowledge On Mind Diet For Early-Onset Alzheimer's Disease, Audrey Marie Rafols

Nursing | Student Research Posters

Adults with Early Onset Alzheimer's Disease (EOAD), is the less common form of the neurodegenerative disease of Alzheimer's Disease (AD), where EOAD is found in adults younger than 65 years old (Alzheimer's Association, 2024). Characterized by a decline of memory, cognitive decline, loss of ability to perform daily tasks involving mobility and communication, EOAD does not have one significant cause. A combination of risk factors are genetics and lifestyle factors such as heart disease, history of stroke, and high blood pressure are associated with increasing the risk of EOAD (National Institute of Aging, 2024).

Since there is no cure for …

The Effectiveness Of Jeffwlp For Weight Loss And General Nutritional Knowledge In Obese Patients, Scott Kozarsky, Ba, Olivia Ackley, Bs, Cynthia Cheng, Md, Phd

Alpha Omega Alpha Research Symposium Posters

PURPOSE: The increasing prevalence of obesity urgently requires effective management strategies. This study evaluates the effectiveness of Jefferson Weight Loss Program (JeffWLP), a trained medical student-delivered health education program in a predominantly African-American patient cohort.

METHODS: A randomized controlled trial was performed enrolling 30 patients with an average socioeconomic status of 5.8 (10 maximum). The intervention group (n=18) completed JeffWLP, a low-cost, 12-week health coaching program combining education sessions with graded step exercises. The control group (n=12) received usual care. Mean baseline age, BMI, and General Nutritional Knowledge Questionnaire (GNKQ) scores were: 46±13 years, 38±5, and 14.7±1.9 (maximum score=17) respectively. …

Improvement Of Hypertension Self-Care Management In African American Older Adults With Uncontrolled Hypertension Through Shared Decision-Making, Sigga Jobe

Doctor of Nursing Practice (DNP) Scholarly Projects - Archive

Background: Hypertension affects nearly half of the population in the U.S., with the prevalence disproportionately higher in African Americans (Centers for Disease Control and Prevention [CDC], 2023). Complications of uncontrolled hypertension, such as cardiovascular disorders and stroke, increase with age, prompting the importance of controlling high blood pressure in older adults. African American older adults are at higher risk of developing uncontrolled hypertension and related complications due to the lack of healthcare access, financial constraints leading to the inability to access healthier food choices, exercise capabilities, weight control, adherence to recommended medications, and knowledge deficit.

Methods: This project focused on …

You Are What You Eat: Social Media's Influence On Health And Beauty Practices For Young Latinx Women, Anaís Martínez Castañeda

Scripps Senior Theses

This thesis delves into the experiences of young Latinx women, exploring how they internalize societal messages propagated through social media that equate whiteness with wellness and beauty standards. Conversations with young LatinX women reveal that performances of whiteness intertwine with dietary practices and notions of thinness, influencing their perceptions and behaviors. This internalization leads to harmful tendencies of body surveillance and diet restriction in an attempt to conform to dominant social media norms. Furthermore, this messaging can result in the rejection of ethnic foods and adversely impact their overall well-being. However, amidst these challenges, participants reevaluated their internalized beliefs and …

Emerging Treatment And Prevention Options In Diet Through The Gut-Brain Axis, And Its Impact On Patients With Alzheimer’S Disease, Jewel Amrich

Theses

Objectives:

To outline the most recent data regarding diet in the role in moderating prevention and progression of Alzheimer’s disease using the relationship between the gut microbiome and central nervous system. In addition, the Mediterranean diet and the components that make up the diet, and those alike will be thoroughly discussed.

Evidence Acquisition:

Using key terms “Alzheimer’s Disease” and “Diet”, Web of Science searched for papers that were published between 2012 and 2023, which yielded 807 results. Refining the search to “Neurodegenerative Diseases” returned 292 results. Adding “Gut-brain axis”, “gut microbiome”, and “Mediterranean diet” to separate search inputs yielded 25 …

Differences In Urine Creatinine And Osmolality Between Black And White Americans After Accounting For Age, Moisture Intake, Urine Volume, And Socioeconomic Status, Patrick B. Wilson, Ian P. Winter, Josie Burdin

Exercise Science Faculty Publications

Urine osmolality is used throughout research to determine hydration levels. Prior studies have found black individuals to have elevated urine creatinine and osmolality, but it remains unclear which factors explain these findings. This cross-sectional, observational study sought to understand the relationship of self-reported race to urine creatinine and urine osmolality after accounting for age, socioeconomic status, and fluid intake. Data from 1,386 participants of the 2009–2012 National Health and Nutrition Examination Survey were utilized. Age, poverty-to-income ratio (PIR), urine flow rate (UFR), fluid intake, estimated lean body mass (LBM), urine creatinine, and urine osmolality were measured. In a sex-specific manner, …

Silver Diamine Fluoride As A Caries Management Option For The Young Child, Giovana Anovazzi Medeiros Dds, Msc, Phd, Chia-En Tsai Dds, Ms, Nita Singh Dds, James R. Boynton Dds, Ms

The Journal of the Michigan Dental Association

Dental caries is among the most-common childhood diseases around the world, and neglected caries can result in pain, infection, and can have a negative cascading impact on a child’s overall well-being. Definitive care of these lesions involves restorative procedures and/or extractions, but these treatment options require some level of child cooperation, which can sometimes be a challenge with very young children.

Silver diamine fluoride (SDF) is a non-invasive treatment intended to arrest the caries process. SDF is a liquid solution that contains a high concentration of silver and fluoride ions and has been used as an alternative agent for treating …

Pediatric Dentists’ Considerations Concerning Obesity-Related Education For Parents Of Young Children: Who Should Educate About What, How And When?, Arianne Swanson Dds, Ms, James R. Boynton Dds, Ms, Larry B. Salzmann Dds, Yu-Ju Yang Dds, Marita R. Inglehart Dipl. Psych., Dr. Phil., Dr. Phil. Habil

The Journal of the Michigan Dental Association

This study aimed to explore pediatric dentists' perspectives on obesity-related interventions for parents of young children. A web-based survey was administered to 210 American Academy of Pediatric Dentistry members. Findings revealed that respondents considered it important for various healthcare professionals, especially pediatricians and nurse practitioners, to engage in obesity-related parent education. Strong consensus existed on educating parents about the link between early childhood caries and diet, soft drink and fruit juice consumption, and healthy snacking. The study also found positive attitudes correlated with increased engagement in objective weight determination, data collection, and diet/nutrition counseling.