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A Data-Driven Approach To Predict Carbohydrate Counting Errors In Diabetes Management, Sahaj Shah

Dartmouth College Undergraduate Theses

Carbohydrate counting, which refers to estimating the carbohydrate content in meals, is critical for determining mealtime insulin doses and maintaining healthy blood glucose levels in persons with type 1 diabetes (T1D). However, carbohydrate counting errors (i.e., over-or under-estimation of carbohydrate intake) are very common amongst patients and are often a source of poor glycemic control. Fortunately, the prevalence of personal health data from wearable medical devices like continuous glucose monitors (CGMs) and insulin pumps provide unique opportunities for understanding and predicting health management outcomes. In this study, we use adverse glycemic events following meal intakes as a proxy for identifying …

Feasibility And Acceptability Of Using Mobile Health Apps In Underserved Patients With Diabetes, Jieyu Luo

Theses and Dissertations (ETD)

Introduction. Diabetes mellitus is a condition with a growing morbidity and mortality burden. An estimated 30 million adults currently live with diabetes, with each individual spending over $9500 annually on medical care. The successful management of diabetes is a lifelong endeavor. This involves balancing a variety of factors including diet, medications, and glucose monitoring. It has been well established that successful control of diabetes depends largely upon patients’ daily lifestyle habits and activities. Not all patients, however, have the resources necessary for effective diabetes management. Health disparities lead to a higher rate of diabetes development in minority and poor populations. …

Impact Of Diabetes Self-Management Education On Adults With Diabetes And Mental Illness, Brooke Tullis

Dissertations

Approximately 9.4% of the population of the United States, or 30.3 million Americans, has diabetes mellitus. Diabetes is the seventh leading cause of death and places a significant financial strain on the healthcare system with approximately $327 billion in estimated expenditures. In Ohio, 13.5% of the population has diabetes, which represents a 4.1% increase above the national average. Additionally, individuals with mental illness are at an increased risk for diabetes due to lower self-efficacy and limited performance of self-care activities compared to the general population. This results in poor glycemic control and leads to an increased risk for diabetes complications. …

Fucoxanthin: A Review Of Potential Benefits Relative To Human Health, Michael R. White

Masters Theses, 2020-current

Fucoxanthin is a carotenoid sourced and extracted mainly from dark orange and brown seaweeds found in the pacific ocean, such as the wakame algae. The allenic bonds and unique oxygen groups give fucoxanthin its unique structure and are thought to be part of the reason fucoxanthin has unique physiological functions. Fucoxanthin has potentially numerous effects on the physiology of human health, ranging from skin health to metabolic health, which have been demonstrated in animal model research. The goal of this review is to examine current literature to discuss fucoxanthin’s potential application as a nutraceutical, treatment for obesity, type 2 diabetes, …

Fucoxanthin: A Review Of Potential Benefits Relative To Human Health, Michael R. White

Masters Theses, 2020-current

Fucoxanthin is a carotenoid sourced and extracted mainly from dark orange and brown seaweeds found in the pacific ocean, such as the wakame algae. The allenic bonds and unique oxygen groups give fucoxanthin its unique structure and are thought to be part of the reason fucoxanthin has unique physiological functions. Fucoxanthin has potentially numerous effects on the physiology of human health, ranging from skin health to metabolic health, which have been demonstrated in animal model research. The goal of this review is to examine current literature to discuss fucoxanthin’s potential application as a nutraceutical, treatment for obesity, type 2 diabetes, …

Diabetes Self-Management Training In Rural Mississippi, Nathan Foxworth

Honors Theses

The objective of this study is to evaluate participants’ attitudes towards and readiness to participate in an online Diabetes Self-Management Education and Support (DSMES) program in rural Mississippi, in light of the rapid shift to telemedicine necessitated by the CoVid19 pandemic. Semi- structured in-depth interviews were conducted with patients over 18 that live in areas considered rural in Mississippi. The findings of the study conclude that patients in rural settings are willing and ready to participate in DSMES online. Of the 12 participants in the study, 11 had access to the internet and had adequate infrastructure in order to participate …

The Emerging Role Of Pancreatic Β-Cell Primary Cilia In Diabetes Mellitus, Emily Blackburn

Honors Scholar Theses

Diabetes mellitus is prevalent in America, affecting more than 10% of the population. The underlying cause of the disease are diverse and can be related to genes, environment and physical inactivity. This review investigates how a minute cellular organelle called primary cilium, found in pancreatic β-cells, affects the development and the function of the pancreas. Gene mutations related to primary cilia can lead to malfunctions or loss of the structure, and cause diseases collectively classified as ciliopathies. Recent studies of two types of ciliopathies, Alstrom’s Syndrome and Bardet–Biedl Syndrome, connect the primary cilium defects with insulin secretion in pancreatic β-cells. …

Effects Of Curcumin And Its Different Formulations In Preclinical And Clinical Studies Of Peripheral Neuropathic And Postoperative Pain: A Comprehensive Review, Paramita Basu, Camelia Maier, Arpita Basu

Kinesiology and Nutrition Sciences Faculty Research

Lesion or disease of the somatosensory system leads to the development of neuropathic pain. Peripheral neuropathic pain encompasses damage or injury of the peripheral nervous system. On the other hand, 10–15% of individuals suffer from acute postoperative pain followed by persistent pain after undergoing surgeries. Antidepressants, anticonvulsants, baclofen, and clonidine are used to treat peripheral neuropathy, whereas opioids are used to treat postoperative pain. The negative effects associated with these drugs emphasize the search for alternative therapeutics with better efficacy and fewer side effects. Curcumin, a polyphenol isolated from the roots of Curcuma longa, possesses antibacterial, antioxidant, and anti-inflammatory properties. …

The Interconnectivity Of Parkinson's Disease And Type Two Diabetes Mellitus, Erica Olfson

Honors Scholars Collaborative Projects

This thesis is about the biochemical connection between Parkinson's disease and Type II Diabetes Mellitus.

Best Practices To Prevent Or Delay Diabetes In Adults With Prediabetes, Aminata Cham

Nursing DNP Projects

Abstract

Diabetes mellitus is a common disease prevalent in 10.5% of the US population about 34.2 million people and a disproportionate percentage of people of color. An EBP project for people with prediabetes was conducted in a faith-based based setting after institutional review board approval. The purpose of the project was to increase fruits and vegetable intake and increase physical activity in adults with prediabetes. The Chronic Care Model was used to guide the design and implementation of the project. The project was a modified version of the National Diabetes Prevention Program (NDPP) in a series of four 2-hour sessions …

How The Symptoms And Conditions Associated With Diabetes Can Impact Mobility And Health Of The Individual: A Literature Review, Kaitlin Grace Fotis

Honors Projects

A literature review on diabetes, diabetic neuropathy, diabetic amyotrophy, sores, ulcers, and amputations, and nephropathy and how, through this snowballing journey, physical therapy can aid an individual. Diabetes can impact the mortality and morbidity of an individual and it alone can have lifelong effects upon the individual. These effects may include dependency upon medication, lifestyle modifications, and diet and physical activity guidelines. If their condition were to worsen, they could find themselves battling circulatory issues and neuropathy thereby hindering their physical function. Many individuals with circulatory issues, diabetic neuropathy, and diabetic amyotrophy develop injuries on their feet like ulcers and …

Racial Disparities In Post-Acute Home Health Care Referral And Utilization Among Older Adults With Diabetes, Jamie Smith, Olga Jarrín, Haiqun Lin, Tina Dharamdasani, Jennifer Tsui, Charlotte Thomas-Hawkins

College of Nursing Faculty Papers & Presentations

Racial and ethnic disparities exist in diabetes prevalence, health services utilization, and outcomes including disabling and life-threatening complications among patients with diabetes. Home health care may especially benefit older adults with diabetes through individualized education, advocacy, care coordination, and psychosocial support for patients and their caregivers. The purpose of this study was to examine the association between race/ethnicity and hospital discharge to home health care and subsequent utilization of home health care among a cohort of adults (age 50 and older) who experienced a diabetes-related hospitalization. The study was limited to patients who were continuously enrolled in Medicare for at …

Glucagon Blockade Restores Functional Β-Cell Mass In Type 1 Diabetic Mice And Enhances Function Of Human Islets, May-Yun Wang, E Danielle Dean, Ezekiel Quittner-Strom, Yi Zhu, Kamrul H Chowdhury, Zhuzhen Zhang, Shangang Zhao, Na Li, Reshing Ye, Young Lee, Yiyi Zhang, Shiuhwei Chen, Xinxin Yu, Derek C Leonard, Greg Poffenberger, Alison Von Deylen, S Kay Mccorkle, Amnon Schlegel, Kyle W Sloop, Alexander M Efanov, Ruth E Gimeno, Philipp E Scherer, Alvin C Powers, Roger H Unger, William L Holland

Faculty, Staff and Students Publications

We evaluated the potential for a monoclonal antibody antagonist of the glucagon receptor (Ab-4) to maintain glucose homeostasis in type 1 diabetic rodents. We noted durable and sustained improvements in glycemia which persist long after treatment withdrawal. Ab-4 promoted β-cell survival and enhanced the recovery of insulin+ islet mass with concomitant increases in circulating insulin and C peptide. In PANIC-ATTAC mice, an inducible model of β-cell apoptosis which allows for robust assessment of β-cell regeneration following caspase-8–induced diabetes, Ab-4 drove a 6.7-fold increase in β-cell mass. Lineage tracing suggests that this restoration of functional insulin-producing cells was at least partially …

Grocery Food Taxes And U.S. County Obesity And Diabetes Rates, Lingxiao Wang, Yuqing Zheng, Steven Buck, Diansheng Dong, Harry M. Kaiser

Agricultural Economics Faculty Publications

BACKGROUND: Grocery food taxes represent a stable tax revenue stream for state and municipal government during times of adverse economic shocks such as that observed under the coronavirus disease 2019 (COVID-19) pandemic. Previous research, however, suggests a possible mechanism through which grocery taxes may adversely affect health. Our objectives are to document the spatial and temporal variation in grocery taxes and to empirically examine the statistical relationship between county-level grocery taxes and obesity and diabetes.

METHODS: We collect and assemble a novel national dataset of annual county and state-level grocery taxes from 2009 through 2016. We link this data to …

Tennessee Diabetes Action Report, February 2021, Tennessee. Department Of Health.

Diabetes Action Report

No abstract provided.

Ten Things To Know About Ten Cardiovascular Disease Risk Factors, Harold E. Bays, Pam R. Taub, Elizabeth Epstein, Erin D. Michos, Richard A. Ferraro, Alison Bailey, Heval M. Kelli, Keith C. Ferdinand, Melvin R. Echols, Salim S. Virani

Office of the Provost

Given rapid advancements in medical science, it is often challenging for the busy clinician to remain up-to-date on the fundamental and multifaceted aspects of preventive cardiology and maintain awareness of the latest guidelines applicable to cardiovascular disease (CVD) risk factors. The "American Society for Preventive Cardiology (ASPC) Top Ten CVD Risk Factors 2021 Update" is a summary document (updated yearly) regarding CVD risk factors. This "ASPC Top Ten CVD Risk Factors 2021 Update" summary document reflects the perspective of the section authors regarding ten things to know about ten sentinel CVD risk factors. It also includes quick access to sentinel …

Doc In The Box: Diabetes Care And Management During Covid-19, Lena K. Heino

Anthropology Honors Projects

Of patients with COVID-19, 94 percent of deaths are patients with pre-existing conditions of pneumonia, hypertension, and diabetes. Current research shows the comorbidity of patients with COVID-19 and Type 2 Diabetes. Despite a growing literature on the interaction of these two diseases, most research focuses on physiological interactions. There remains a pressing need for research on the biosocial mechanisms contributing to the interaction between Diabetes and COVID-19. This research focuses on the social conditions constructed during COVID-19 that influence the care and management of Type 2 Diabetes. To investigate the topic, I conducted interviews with healthcare providers and community leaders …

Examining Clinicians' Perspectives Screening For Depression In Patients With Type 2 Diabetes Mellitus, Vickie Lavette Bland

Walden Dissertations and Doctoral Studies

The United States has a significant diabetes problem. This chronic disease affects the body physically and mentally. One of the emotional effects of diabetes is depression. Depression is often present in individuals with diabetes, chiefly in those with type 2 diabetes mellitus (T2DM). While depression is common in T2DM and can interfere with treatment adherence, clinician screening for depression in T2DM patients is low. The purpose of this study was to examine clinicians' attitudes, behaviors, and perceptions concerning screening patients with T2DM for depression. Through a qualitative case study approach centered on reasoned action theory, 3 physicians and 5 nurse …

Social Determinants Of Health And Type 2 Diabetes Among Enrollees Of California Children’S Services Program In Fresno County, California, Daniela Marie Aghadjanian

Walden Dissertations and Doctoral Studies

Despite extensive study in adults, Type 2 diabetes (T2D) has been the subject of little research concerning young adults or children. Doctors believed T2D to develop only in a person’s later years until health care providers found younger individuals developing this disease. The purpose of this cross-sectional quantitative analysis was to determine correlations between T2D and social determinants of health in Fresno County, California, based on children and adolescents. The 2017-19 data came from the Fresno County Department of Public Health. The theoretical foundation for the study was the socio-ecological framework focusing on individuals’ traits having a bidirectional impact on …

Pharmacological Management Of The Diabetic Patient: A Staff Education Project, Wilantha Silva

Walden Dissertations and Doctoral Studies

Poorly controlled diabetes can lead to health complications that impact quality of life, increase healthcare costs, and create a negative impact on communities. Pharmacological management of diabetes was identified by stakeholders as a gap in practice at a clinic in the southeastern United States. The purpose of this project was to develop staff education based on American Diabetes Association (ADA) and American Association of Clinical Endocrinologists (AACE) standards of care, deliver education to primary care nurse practitioners (NPs), and evaluate their learning and confidence levels. The primary framework for this project was the chronic care model. An expert panel, including …

Three Essays On Grocery Sales Taxes, Lingxiao Wang

Theses and Dissertations--Agricultural Economics

Grocery sales taxes represent a stable tax revenue stream for state and municipal government, but there is rare empirical evidence suggesting grocery taxes may adversely affect health. In addition, the how governments set grocery sales taxes is still unclear. Therefore, based on a novel national dataset of annual county and state-level grocery taxes from 2009 through 2016, the following three essays in the dissertation investigate the health impacts of grocery sales taxes and the causes of grocery sales taxes in a framework of tax competition.

In the first essay, we document the spatial and temporal variation in grocery taxes and …

The Importance Of Staff Education About Implementing Ketogenic Diet In Prediabetic Patients, Clarissa L. Dorsey

Walden Dissertations and Doctoral Studies

Diabetes, a chronic disease that can lead to many complications, is one of the leading causes of death. Obesity tends to increase the risk of diabetes. Nutritional therapy can not only control diabetes but also prevent it in some cases by decreasing weight. The ketogenic diet is a low-carbohydrate, high-fat diet that can prevent and control diabetes. The purpose of this study was to examine the recommendations of medical providers before and after the presentation of educational content on the ketogenic diet as nutritional therapy in prediabetic and diabetic patients. The practice-focused question addressed whether educating medical staff at a …

Impact Of Audit And Feedback On Timing Variation In The Point Of Care Glucose Collection-Insulin Administration Workflow: A Quality Improvement Study, Paula S. Hudon

DNP Scholarly Projects

BACKGROUND: Multiple roles contribute to the point of care glucose collection and insulin administration workflow. Diabetes care associations and safety advocates provide recommendations since the time-action profile of prandial insulin requires knowledge and performance to deliver insulin safely.

PROBLEM: Variation of practice in relation to the time that point of care glucose was collected and meal and insulin administration assessments were completed failed to meet parameters.

PURPOSE: A quality improvement project aimed to test the effect audit and feedback has on rapid acting insulin administration and point of care glucose collection practice at meals.

METHOD: Audit and feedback, a knowledge …

Associations Between Fruit Intake And Risk Of Diabetes In The Ausdiab Cohort: Supplementary Material, Nicola P. Bondonno, Raymond J. Davey, Kevin Murray, Simone Radavelli-Bagatini, Catherine P. Bondonno, Lauren C. Blekkenhorst, Marc Sim, Dianna J. Magliano, Robin M. Daly, Jonathan E. Shaw, Joshua R. Lewis, Jonathan M. Hodgson

Research Datasets

Supplementary Material accompanying manuscript entitled ‘Associations between fruit intake and risk of diabetes in the AusDiab cohort’.

Identifying Critical Features Of Type Two Diabetes Prevention Interventions: A Delphi Study With Key Stakeholders, Jillian C. Ryan, Bonnie Wiggins, Sarah Edney, Grant D. Brinkworth, Natalie D. Luscombe-March, Kristin V. Carson-Chahhoud, Pennie J. Taylor, Annemien A. Haveman-Nies, David N. Cox

Research outputs 2014 to 2021

Aims This study aims to identify critically important features of digital type two diabetes mellitus (T2DM) prevention interventions. Methods A stakeholder mapping exercise was undertaken to identify key end-user and professional stakeholders, followed by a three-round Delphi procedure to generate and evaluate evidence statements related to the critical elements of digital T2DM prevention interventions in terms of product (intervention), price (funding models/financial cost), place (distribution/delivery channels), and promotion (target audiences). Results End-user (n = 38) and professional (n = 38) stakeholders including patients, dietitians, credentialed diabetes educators, nurses, medical doctors, research scientists, and exercise physiologists participated in the Delphi study. …

The Impact Of Identifying And Addressing The Social Needs Of Patients With Type 2 Diabetes Mellitus In A Primary Care Clinic, Shelby Roberts

DNP Projects

BACKGROUND: A key aspect of successful Diabetes management is addressing social needs. Patients prefer individualized care that is tailored to their specific needs.

PURPOSE: The purpose of this Doctor of Nursing Practice (DNP) quality improvement project was to screen patients regarding their diabetes distress and social needs requirements to develop and implement individualized social needs interventions.

METHODS: Patients were included in the study if they had a Hemoglobin A1C >9. Patients were screened, provided additional check in points and social needs were addressed in conjunction with the patient’s primary care provider and onsite social worker. Post intervention …

Healthy Your Way, Susan Newkirk

All Student-Created Educational Resources

This handout depicts four lifestyle habits to integrate into everyday life to reduce your risk obesity and chronic diseases.

A Lesson Involving Nursing Management Of Diabetes Care: Incorporating Simulation In Didactic Instruction To Prepare Students For Entry-Level Practice, Elizabeth A. Moxley, Larry Maturin Jr., Desale Habtzghi

Faculty Articles, Papers, and Other Scholarship

Background: Diabetes is a global health problem requiring nursing students demonstrate a thorough understanding for NCLEX^® and entry-level practice, although clinical opportunities are increasingly limited, especially for Associate Degree Programs.

Method: A Simulation-based Education was incorporated in a didactic lesson to improve diabetes nursing care. Knowledge, confidence, application and relevance were measured using Wilcoxon signed-rank, Chi-square and Kruskal-Wallis analyses.

Results: Student (n=46, 85% female) perceived knowledge of glycemic management (post > pre, p < 0.0001), confidence administering insulin (post > pre, p < 0.0001), and clinical relevance improved. Confidence increased among three cohorts per Kruskal Wallis H test (² = 7.76, p = 0.021). Increased confidence correlated with relevance (² = 30.965, p = 0.009) and prior understanding of therapy ( …

The Role Of Race, Sex, And Place In The Association Of Diabetes And Cardiovascular Disease, Gargya Malla

All ETDs from UAB

Cardiovascular disease risk is higher among adult with diabetes than those without diabetes. This increase in risk may vary by race, sex, and neighborhood characteristics. Recent US data showed a resurgence in stroke and coronary heart disease (CHD) among adults with diabetes, and an increase in heart failure (HF) mortality. Therefore, this dissertation investigated how cardiovascular disease risk may vary by race, sex, and neighborhood characteristics for adults across the glycemic spectrum.Data from the REasons for Geographic and Racial Differences in Stroke (REGARDS) study, an ongoing prospective cohort of 30,239 Black and White adults age 45 years at baseline (2003-07) …

Assessing Consistency With Standards Of Care Recommendations For Patients With Type 2 Diabetes At Hospital Discharge, Katherine Brown Pharmd, Timothy L. Johnston Bpharm, Pharmd, Bcps, Bcccp, Andrea Sloat Pharmd

Parkview Pharmacy Department

2021 ASHP Midyear Clinical Meeting / Poster ID#1129514

Objective: To assess the number of patients prescribed diabetic regimens consistent with American Diabetes Association (ADA) Standards of Care recommendations upon hospital discharge.