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Final Capstone Research Report : Watsonville High School Promoters Of Healthy Lifestyles : A Teen Diabetes Support Group, Isabel Lopez

Capstone Projects and Master's Theses

This is a pilot Diabetes Teen Support program for Watsonville High School students of Hispanic decent in South Santa Cruz County. The program focuses on understanding diabetes, obesity and overweight problems, the impacts of diabetes on daily lives, self management and a safe place to express their feelings. The findings of this pilot program were that the program had impact on students' lives in many ways, from being aware of their actions, their socioeconomic position and creating opportunities for change.

Environmental Influences On Adherence To Self-Management Behaviors And Glycemic Control In African American Patients With Type 2 Diabetes Mellitus, Brooke L. Barbera

LSU Master's Theses

Diabetes mellitus is a chronic illness effecting approximately 20.8 million individuals in the United States. Minorities are adversely affected, with age-adjusted prevalence 1.7 times higher in African Americans than Caucasians. Type 2 diabetes is significantly affected by behavioral and environmental risk factors, including the presence of co-occurring diseases (i.e., hypertension, hyperlipidemia), obesity, age, and lack of physical activity, and each of these risk factors is more prevalent among African Americans. The treatment of diabetes is largely self-managed, with patients and their families handling 95% of their own care. Adherence to the multi-component diabetic treatment regimen requires daily care, often occurring …

Growth Environment And Sex Differences In Lipids, Bodyshape And Diabetes Risk, Mary Schooling, Tai Hing Lam, G. Neil Thomas, Benjamin J. Cowling, Michelle Heys, Edward D. Janus, Gabriel M. Leung

Publications and Research

Background
Sex differences in lipids and body shape, but not diabetes, increase at puberty. Hong Kong Chinese are mainly first or second generation migrants from China, who have shared an economically developed environment for years, but grew up in very different environments in Hong Kong or contemporaneously undeveloped Guangdong, China. We assessed if environment during growth had sex-specific associations with lipids and body shape, but not diabetes.

Methodology and Principal Findings
We used multivariable regression in a population-based cross-sectional study, undertaken from 1994 to 1996, of 2537 Hong Kong Chinese residents aged 25 to 74 years with clinical measurements of …

Pparα Is A Key Regulator Of Hepatic Fgf21, Thomas Lundasen, Mary Hunt, Lisa-Marie Nilsson, Sabysashi Sanyal, Bo Angelin, Stefan Alexson, Mats Rudling

Articles

The metabolic regulator fibroblast growth factor 21 (FGF21) has antidiabetic properties in animal models of diabetes and obesity. Using quantitative RT-PCR, we here show that the hepatic gene expression of FGF21 is regulated by the peroxisome proliferator-activated receptor alpha (PPARalpha). Fasting or treatment of mice with the PPARalpha agonist Wy-14,643 induced FGF21 mRNA by 10-fold and 8-fold, respectively. In contrast, FGF21 mRNA was low in PPARalpha deficient mice, and fasting or treatment with Wy-14,643 did not induce FGF21. Obese ob/ob mice, known to have increased PPARalpha levels, displayed 12-fold increased hepatic FGF21 mRNA levels. The potential importance of PPARalpha for …

A Hierarchy Of Medicine: Health Strategies Of Elder Khmer Refugees In The United States, Denise C. Lewis

The Qualitative Report

This study addresses ways Khmer refugee elders utilize traditional herbal medicine with Western biomedicine in the treatment and prevention of illnesses. Methods include semi-structured and informal interviews with elders and family members, semi-structured interviews with local health care providers and Khmer physicians, and participant observation of everyday life and actions specific to health beliefs and behaviors. Data reveal a reliance on traditional medical ideology for understanding and treating illnesses. Utilizing a traditional ideology, Khmer elders rely heavily on traditional treatments and use Western biomedicine as supplements or adjuncts to traditional preventive and curative practices. This research has important implications for …

Developing A Support Group For Adolescents With Insulin-Dependent Diabetes Mellitus Using An Outdoor Adventure Educational Modality, Tara Lynch

Graduate Student Independent Studies

This independent study details the group process aspects of creating an outdoor adventure based support group for adolescents living with insulin-dependent diabetes mellitus (IDDM). A review of previous outdoor adventure programs is included, followed by a rationale for the new material. The developmental assessment of teens living with IDDM identifies a need for greater self-confidence, increased independence, and social support. To meet this need, a program that includes aspects of team building, personal challenge, and problem-solving has been created.

One-Year Changes In Glucose And Heart Disease Risk Factors Among Participants In The Wisewoman Programme, Jc Will, O Khavjou, Ea Finkelstein, Rk Loo, Ky Gregory-Mercado

United States Public Health Resources

Background: WISEWOMAN provides chronic disease risk factor screening, referrals and lifestyle interventions to low-income, uninsured women, to reduce their heart disease and stroke risk. Participants learn behaviour-changing skills tailored to low-income populations, such as collaborative goal setting, the need to take small steps and other empowerment techniques.

Aim: To quantify the baseline prevalence of pre-diabetes (fasting blood glucose 5.5–6.9 mmol/l) and diabetes among WISEWOMAN participants and assess one year changes in glucose levels and other diabetes risk factors.

Methods: We used 1998–2005 baseline and one-year follow-up data from WISEWOMAN participants. Using a multilevel regression model, we assessed …

Office Nurse Educators: Improving Diabetes Self-Management For The Latino Population In The Clinic Setting, Dawn Weiler, Laura Tirrell

Nursing Faculty Publications and Presentations

Diabetes patients who understand their disease and how to manage it can achieve a lower complication rate. The American Diabetes Association recommends that patients receive self-management education and that patients' skills and knowledge be reassessed annually. The Healthy People 2010 objectives include a goal of at least 60% of diabetes patients receiving diabetes education. However, to date overall, far fewer (20%–50%) obtain comprehensive diabetes education and skills development to effectively implement self-management techniques. Low-income Latino patients generally fare even worse. This article describes a successful method to address this problem: the development and evaluation of an in-house diabetes education program, …

Medicine And Public Health: Crossing Legal Boundaries, Wendy K. Mariner

Faculty Scholarship

In 2006, New York City began a mandatory reporting system for laboratories to submit blood sugar (A1c) test results (primarily for diabetes) to the city's Department of Health and Mental Hygiene without the patient's consent. This article examines whether this new program is an innovative way to improve New Yorkers' health, an invasion of medical privacy, or usurpation of the physician's role. The registry is an example of public health initiatives in chronic diseases, which challenge the limits of laws governing medicine care and public health programs by blurring the historical boundaries between them.

Review Of Diabetes Among Indigenous Peoples, Australian Indigenous Healthinfonet

Research outputs pre 2011

This review provides detailed information on the extent of diabetes, and its complications and comorbidities among Aboriginal and Torres Strait Islander people, including: incidence and prevalence data; hospitalisations; mortality and burden of disease. This review discusses the issues of prevention and management of diabetes, and provides information on relevant programs, services, policies and strategies that address the health issue of diabetes among Aboriginal and Torres Strait Islander people.

This review concludes by discussing possible future directions for combatting the growing epidemic of diabetes in Australia.

The review focuses primarily on type 2 diabetes among Aboriginal and Torres Strait Islander people …

Oxpat/Pat-1 Is A Ppar-Induced Lipid Droplet Protein That Promotes Fatty Acid Utilization, Nathan E. Wolins, Benjamin K. Quaynor, James R. Skinner, Anatoly Tzekov, Michelle A. Croce, Matthew C. Gropler, Vijayalakshmi Varma, Aiwei Yao-Borengasser, Neda Rasouli, Philip A. Kern, Brian N. Finck, Perry E. Bickel

Clinical and Translational Science Faculty Publications

Lipid droplet proteins of the PAT (perilipin, adipophilin, and TIP47) family regulate cellular neutral lipid stores. We have studied a new member of this family, PAT-1, and found that it is expressed in highly oxidative tissues. We refer to this protein as "OXPAT." Physiologic lipid loading of mouse liver by fasting enriches OXPAT in the lipid droplet tissue fraction. OXPAT resides on lipid droplets with the PAT protein adipophilin in primary cardiomyocytes. Ectopic expression of OXPAT promotes fatty acid-induced triacylglycerol accumulation, long-chain fatty acid oxidation, and mRNAs associated with oxidative metabolism. Consistent with these observations, OXPAT is induced in mouse …

Diabetes Alters Vascular Mechanotransduction: Pressure-Induced Regulation Of Mitogen Activated Protein Kinases In The Rat Inferior Vena Cava, Kevin M. Rice, Devashish H. Desai, Sunil K. Kakarla, Anjaiah Katta, Deborah L. Preston, Paulette Wehner, Eric R. Blough

MIIR Faculty Research

Background

Diabetes mellitus is an important risk factor for increased vein graft failure after bypass surgery. However, the cellular and molecular mechanism(s) underlying vessel attrition in this population remain largely unexplored. Recent reports have suggested that the pathological remodeling of vein grafts may be mediated by mechanically-induced activation of the mitogen activated protein kinase (MAPK) signaling pathways and the MAPK-related induction of caspase-3 activity. On the basis of these findings, we hypothesized that diabetes may be associated with alterations in how veins "sense" and "respond" to altered mechanical loading.

Methods

Inferior venae cavae (IVC) from the non-diabetic lean (LNZ) and …

The Antagonistic Role Of Cinnamon On A Destructive Effect 0f Alloxan On The Rat Testis . A Histological Study, Mahera N . Al - Shaikh, An H . Al - Khalasi, Nameer T . George

Iraqi Postgraduate Medical Journal

ABSTRACT: BACKGROUND: Diabetes mellitus is a chronic metabolic disorder characterized by a high blood glucose concentration (hyperglycemia ) which is due to insulin deficiency and / or insulin resistance . As a consequence of the metabolic derangements various complications develop , so the aim of this investigation is to study(histological ) the role of cinnamon – oil on the testis tissue of alloxan – induced diabetes rat . METHODS AND METHODS : Forty -six male rats were used and divided into 3 groups : group I , 6 = animal control . group II , 20 = treated with alloxan …

The Wooster Voice (Wooster, Oh), 2006-02-10, Wooster Voice Editors

The Voice: 2001-2011

This edition of the College of Wooster's student run newspaper was published on February 10 of 2006, and it is eight pages long. February 1 marked the beginning of Black History Month, many activities and speeches will be occurring throughout the month. An article about the rapid growth of Diabetes is on the first page. New Member Education was reinstated by President Hales on Friday. Tuition is increasing by $2,080 for next school year. Ideas for Valentine's Day, some history, love songs, and Voice Valentines are all on page four. A review of the store located downtown, Friendtique, is on …

Renal Dysfunction, Cardiovascular Risk, And The Response To Ace Inhibition In Patients After Myocardial Infarction, Powell Oliapuram Jose

Yale Medicine Thesis Digital Library

Background: Proteinuria is a known cardiovascular risk factor in hypertensive or diabetic patients as well as the general population. Worsening renal function (WRF) has been shown to influence outcomes in the heart failure population. The prognostic value of these markers for renal dysfunction in patients after myocardial infarction is unclear. Methods: The Survival and Ventricular Enlargement trial (SAVE) randomized 2231 patients with left ventricular dysfunction between 3-16 days (average 11 days) post-MI to receive captopril or placebo; those with a serum creatinine above 2.5mg/dl were excluded from SAVE. WRF was defined as an increase in creatinine greater-than 0.3mg/dl measured from …

Diabetes Self-Management: Patient Cognition And The Development Of Expertise, Katherine D. Lippa

Browse all Theses and Dissertations

Expert decision making has been widely researched among professionals, but non-professionals make many equally complex decisions. This study uses the case of type II diabetes to explore complex decision making among non-professionals. It was hypothesized that three cognitive aspects of expertise, problem detection, functional relationships, and problem solving, would be linked with higher levels of self-management (higher adherence and lower glucose). Twenty participants with diabetes were interviewed concerning their knowledge and experiences with diabetes. Participants also completed a questionnaire concerning their self-management practices. Interviews were transcribed and thematically coded. Participants who displayed characteristics of expert cognition reported higher levels of …

The Etiological Role Of Susto In Diabetes Among Hispanics In Southern Nevada, Carin K Wallace

UNLV Retrospective Theses & Dissertations

This thesis explores the association between susto, a Hispanic folk explanation of disease, and type 2 diabetes. This association is explored through a focus group and semi-structured interviews, with participants recruited from a population of 300 diabetes patients under treatment by a local non-profit group. Results show that not only is susto thought to be an important cause of diabetes among Hispanic diabetics and their family members, but that the meaning of susto may be changing; no longer thought of as solely a frightful event, it is a description of the resulting emotions as well. The role of emotions such …

Availability Of Emotional Support, Conflictual Interactions, And Coping As Predictors Of Adherence And Affect In Individuals With Diabetes, Misty D. Hixon

Psychology Theses & Dissertations

Although the treatment of diabetes is often complex and demanding, it is necessary. Unfortunately studies show that current adherence rates are at a disappointingly low level. Additionally, individuals diagnosed with diabetes often report high levels of negative mood, depression, and anxiety. The purpose of this study was to contribute to the understanding of adherence to diabetes treatment regimens and mood states in individuals with diabetes by examining the associations among availability of social support, conflictual social interactions, coping, mood states, and adherence. One hundred and fourteen individuals with types 1 and 2 diabetes were recruited and completed either an online …

Depression And Glycemic Control In Hispanic Primary Care Patients With Diabetes, Raz Gross, Mark Olfson, Marc J. Gameroff, Olveen Carasquillo, Steven Shea, Adriana Feder, Rafael Lantigua, Milton Fuentes, Myrna M. Weissman

Department of Psychology Faculty Scholarship and Creative Works

CONTEXT: Maintaining optimal glycemic control is an important goal of therapy in patients with diabetes mellitus. Patients of Hispanic ancestry have been shown to have high rates of diabetes and poor glycemic control (PGC). Although depression is common in adults with diabetes, its relationship to glycemic control remains unclear, especially among Hispanics. OBJECTIVE: To assess the association of depression with PGC in Hispanics. DESIGN: Data from a cross-sectional mental health survey in primary care were crosslinked to the hospital's computerized laboratory database. SETTING: Urban general medicine practice at a teaching hospital. PATIENTS: Two hundred and nine patients (mean [standard deviation] …

Diabetes, Cognitive Decline, And Alzheimer's Disease: The Cache County Study On Memory, Health, And Aging, Gene Charoonruk

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Studies have reported mixed results for people with or without diabetes with cognitive decline or Alzheimer's disease (AD). Cognitive decline and AD among people with diabetes will be the focus of much discussion since results have been controversial.

The study examined whether diabetes is associated with cognitive decline and whether it is an independent risk factor for the development of AD among elderly residents of Cache County, Utah.

Results revealed an association between diabetes and a lower average Modified Mini Mental State Examination (3MS) score of nearly a point lower at baseline. Results also showed an association between diabetes and …

The Prevalence Of Comorbid Chronic Disease In Virginia's Adult Patient Population During The Years 2001 And 2004, Joseph D. Schwartz

Theses and Dissertations

Objective: Chronic disease comorbidities, on the rise in the U.S. and Virginia, represent a new challenge to the way medicine is practiced and prescribed. This descriptive study uses Virginia hospital discharge data to describe the prevalence and trends of chronic disease comorbidities present in the state's over-45 population during the years 2001 and 2004.Methods: Data collected by Virginia Health Information was utilized. Adults over the age of 45 years and who selected for race and location were included in this analysis, with an aggregate sample size of 813,336 (N=458,593 [2001]; N=364,743 [2004]). Pearson chi-square analyses determined significant sample population differences …

Parental Memory Predictors Of Children's Daily Diabetes Management And Metabolic Control, Sheryl J. Kent

Theses and Dissertations

This study examined, for the first time, specific links between parents' memory and children's diabetes behaviors and metabolic control. Data revealed that parental memory and responsibility predicted children's percentage of calories from fat and carbohydrates, and metabolic control, accounting for 7.3% of the variance in calories from fat and 18.5% of the variance in metabolic control for the total sample. These effects were stronger when limited to dietary behaviors of younger youth; parental memory accounted for 30.3% and 33.6% of the variance in percentage of calories from fat and carbohydrates, respectively, for younger children. Level of parent responsibility, with memory, …

Diabetes Stepping Up To The Plate: An Education Curriculum Focused On Food Portioning Skills, D. Pauline Williams, Heidi Leblanc, Nedra K. Christensen

Nutrition, Dietetics, and Food Sciences Faculty Publications

The Diabetes Stepping up to the Plate program was developed to determine the effectiveness of food portion based diabetes education. One hundred fifty-one individuals enrolled in the diabetes series. Food portion knowledge and skills tests, height, weight, and waist-to-hip ratio (WHR) were measured pre- and post-program. Data was analyzed through paired t-tests and correlations. Evaluation showed a decrease in HbA1C, waist/hip circumference, WHR, and BMI, and an improvement in food portion knowledge and skills. Seventy-five participants completed pre- and post-data collection parameters, although more participants completed all classes in the series. Extension can play a role in successful diabetes education.

Magnesium Intake And Its Relationship With Type 2 Diabetes, Caralee Wilcock

Undergraduate Honors Capstone Projects

Magnesium is an alkaline earth metal and is the second most abundant cation in the human body. Magnesium plays important roles in the structure and the function of the human body; it is involved in more than 300 essential metabolic reactions in the body. Magnesium has been implicated in the prevention and treatment of many diseases including diabetes. Magnesium depletion is commonly associated with both insulin dependent and non-insulin dependent diabetes. A significant number, (between 25% and 39%) of diabetics have been shown to have decreased serum levels of magnesium. There are many possible reasons and mechanisms for this. Diabetics …

The Influence Of Social And Environmental Support On Diabetes Self-Management, Cheryl Mckee

Theses and Graduate Projects

Background The reduction of diabetes complications depends on adherence to self-management behaviors. The current study was designed to examine the influence of multiple social-environmental levels of support on diabetic self-management behaviors in a lower income community. The eight distinct levels of social-environmental support studied were personal characteristics, physician and health team, family and friends, neighborhood, community, media and policy, community organizations, and the workplace. Methods An anonymous self-administered survey, consisting of questions about demographic features, hemoglobin AlC, self-management behaviors, and perceived support from multiple social-environmental levels, was completed by 36 diabetic participants from the Regions Family Physicians clinic. Results Significant …

Obesity And Health Status Among Urban Vs. Suburban Elderly In Philadelphia And Surrounding Counties, Ockidde Dufayne Harris

Theses and Dissertations

Obesity is a dangerous health condition affecting approximately 30% of all Americans and can be attributed to 300,000 deaths a year. Obesity has been found to disproportionately affect Blacks, Latinos, and those with lower SES. Although obesity is a problem for all age groups, its prevalence is highest among those 60-74 years of age. Studies have shown that there is an association between obesity and chronic conditions such as cardiovascular disease, arthritis, cancers, and type-2 diabetes. According to the Centers for Disease Control, chronic health conditions affect 80% of all elderly persons, many times limiting function and decreasing quality of …

Studies Of The Effects Of Pancreatic Beta Cell Antioxidant Transgenes On Experimental Models Of Diabetes., Hainan Chen

Electronic Theses and Dissertations

Pancreatic beta cells are extremely vulnerable to the destruction of Reactive Oxygen Species (ROS). In both type 1 and type 2 diabetes ROS are involved in the loss of U+000DF-cells. We hypothesized that the deficiency in ROS detoxifying system of U+000DF-cells resulted in U+000DF-cell vulnerability and enhanced ROS protection would protect from diabetes. To test this hypothesis, transgenic mice with overexpression of U+000DF-cell antioxidant protein metallothionein (MT), manganese superoxide dismutase (MnSOD) and catalase were produced on an FVB background. Initial studies demonstrated that these transgenes did not affect U+000DF-cell normal function and morphology. But those transgenes significantly protected pancreatic islets …

Increasing Diabetes Awareness In Adolescents Through Educational Programs., Sandra J. Reese

Electronic Theses and Dissertations

The purpose of this study was to increase knowledge of diabetes and promote healthy lifestyle behaviors to reduce diabetes onset in a community with a relatively high incidence of type 2 diabetes. Three hundred eighty seven students grades 7 – 12 participated in the program and taste test. Changes in knowledge before and after an educational program focusing on diabetes prevention were measured by comparison of identical pre, post, and retention tests. Students were also asked to name specific behaviors they could use to decrease the risk of diabetes. Responses were analyzed using Chi square analysis and content analysis. Overall, …

Effects Of Diabetes And Aging On Posture And Acceleration Thresholds During Lateral Translations, Samantha Jean Richerson

Doctoral Dissertations

Research objectives. One source of falls in the elderly may be an inability to sufficiently adjust to transient postural perturbations or slips. Identifying useful predictors of fall potential, as well as factors that affect the ability of an individual to detect a movement of the standing support surface may provide insight into postural stability and methods to increase stability in elders. To do this, acceleration thresholds to short, precise, lateral platform translations and the resultant psychophysical responses of adults with early Type 2 diabetes to age-matched controls and young adults were measured.

Methods. Using an innovative SLIP-FALLS platform, …

Adherence To Medical Regimens In Low-Income Adults With Type 2 Diabetes: The Influence Of Perceived Control Constructs, Erin L. O'Hea

LSU Doctoral Dissertations

Individuals with Type 2 diabetes often do not adhere to their treatment regimens (e.g., exercise, diet, medication, glucose monitoring). Non-adherence results in poor metabolic control, further morbidity and mortality, and increased health care utilization and costs. One common thread among many health-behavior-theories that attempt to explain non-adherence behaviors is the importance of perceived control. This psychosocial variable has most often been conceptualized as ‘health locus of control,’ which refers to the belief that one has the ability to influence or change one’s health outcomes. Inconsistent findings have been reported regarding the relationship of health locus of control and medical regimen …