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The Mind And Crime: Criminal Victimization, Age, And Psychological Wellbeing, Alana Compton

Student Scholar Showcase

The purpose of this study was to examine the relationship between crime victimization, age at the time of victimization, and psychological health. Past research has shown that crime victimization has been linked to higher levels of depression and suicidal ideation, anxiety, posttraumatic stress disorder (PTSD), and eating disorders, and that those who experience a traumatic event as a child are influenced more negatively than those who experience trauma as an adult. Undergraduate students, graduate students, and faculty and staff were surveyed to determine their experiences with crime, age, and levels of depression, anxiety, PTSD, eating disorder symptomology, and resilience. The …

Cross-Sectional Study To Assess Depression Among Healthcare Workers In Lusaka, Zambia During The Covid-19 Pandemic, Sandra Simbeza, Jacob Mutale, Musunge Mulabe, Lazarus Jere, Chama Bukankala, Kombatende Sikombe, Izukanji Sikazwe, Carolyn Bolton-Moore, Aaloke Mody, Elvin H. Geng, Anjali Sharma, Laura K. Beres, Jake M. Pry

2020-Current year OA Pubs

OBJECTIVES: We sought to assess depression among healthcare workers (HCWs) in the context of COVID-19 in Lusaka Province, Zambia.

DESIGN: This cross-sectional study is nested within a larger study, the Person-Centred Public Health for HIV Treatment in Zambia (PCPH), a cluster-randomised trial to assess HIV care and outcomes.

SETTING: The research was conducted in 24 government-run health facilities from 11 August to 15 October 2020 during the first wave of the COVID-19 pandemic in Lusaka, Zambia.

PARTICIPANTS: We used convenience sampling to recruit HCW participants who were previously enrolled in the PCPH study, had more than 6 months' experience working …

Co-Occurrence Of Depression, Anxiety, And Perinatal Posttraumatic Stress In Postpartum Persons, Shelby Howard, Caitlin Witt, Karla Martin, Ateshi Bhatt, Emily Venable, Sarah Buzhardt, Andrew G. Chapple, Elizabeth F. Sutton

School of Medicine Faculty Publications

Background: The study aim was to describe the incidence of depression, anxiety, perinatal-post-traumatic stress disorder (PTSD), and their co-occurrences in the early postpartum period in a low-resource OB/GYN clinic serving majority Medicaid-eligible persons. We hypothesized that postpartum persons screening positive for depression will have an increased risk of a positive screen for anxiety and perinatal PTSD. Methods: A retrospective study of postpartum persons receiving care in Baton Rouge, Louisiana was conducted using responses abstracted from the electronic medical record (EMR) of the Patient Health Questionnaire-9 (PHQ9), Generalized Anxiety Disorder-7 (GAD7), and Perinatal Post Traumatic Stress Disorder Questionnaire-II (PPQII). Categorical distributions …

Depression And Anxiety: Experiences, Symptoms, And Help Seeking Attitude Differences Between Males And Females, Jenna K. Groom

Honors College Theses

The current study examined the differences in experiences of depression and anxiety, symptoms, and help-seeking behaviors between males and females. The importance of this research was to better understand the impact that sex has on how individuals are affected by and live with mental illnesses like depression and anxiety. Participants took an online survey that asked them a series of questions about their experiences with mental illness, their perceptions of mental illness, and their ideas toward mental health assistance. T-test analyses and correlations were conducted in order to better understand how males and females differ when it comes to mental …

Assessment Of Psychosocial And Neonatal Risk Factors For Trajectories Of Behavioral Dysregulation Among Young Children From 18 To 72 Months Of Age, Julie A. Hofheimer, Monica Mcgrath, Rashelle Musci, Guojing Wu, Sarah Polk, Courtney K. Blackwell, Annemarie Stroustrup, Robert D. Annett, Judy Aschner, Brian S. Carter, Jennifer Check, Elisabeth Conradt, Lisa A. Croen, Anne L. Dunlop, Amy J Elliott, Andrew Law, Leslie D. Leve, Jenae M. Neiderhiser, T Michael O'Shea, Amy L. Salisbury, Sheela Sathyanarayana, Rachana Singh, Lynne M. Smith, Andréa Aguiar, Jyoti Angal, Hannah Carliner, Cindy Mcevoy, Steven J. Ondersma, Barry Lester, Program Collaborators For Environmental Influences On Child Health Outcomes

Pediatrics Research and Scholarship

IMPORTANCE: Emotional and behavioral dysregulation during early childhood are associated with severe psychiatric, behavioral, and cognitive disorders through adulthood. Identifying the earliest antecedents of persisting emotional and behavioral dysregulation can inform risk detection practices and targeted interventions to promote adaptive developmental trajectories among at-risk children.

OBJECTIVE: To characterize children's emotional and behavioral regulation trajectories and examine risk factors associated with persisting dysregulation across early childhood.

DESIGN, SETTING, AND PARTICIPANTS: This cohort study examined data from 20 United States cohorts participating in Environmental influences on Child Health Outcomes, which included 3934 mother-child pairs (singleton births) from 1990 to 2019. Statistical analysis …

Assessment Of Psychosocial And Neonatal Risk Factors For Trajectories Of Behavioral Dysregulation Among Young Children From 18 To 72 Months Of Age., Julie A. Hofheimer, Monica Mcgrath, Rashelle Musci, Guojing Wu, Sarah Polk, Courtney K. Blackwell, Annemarie Stroustrup, Robert D. Annett, Judy Aschner, Brian S. Carter, Jennifer Check, Elisabeth Conradt, Lisa A. Croen, Anne L. Dunlop, Amy J. Elliott, Andrew Law, Leslie D. Leve, Jenae M. Neiderhiser, T Michael O'Shea, Amy L. Salisbury, Sheela Sathyanarayana, Rachana Singh, Lynne M. Smith, Andréa Aguiar, Jyoti Angal, Hannah Carliner, Cindy Mcevoy, Steven J. Ondersma, Barry Lester, Program Collaborators For Environmental Influences On Child Health Outcomes

Manuscripts, Articles, Book Chapters and Other Papers

IMPORTANCE: Emotional and behavioral dysregulation during early childhood are associated with severe psychiatric, behavioral, and cognitive disorders through adulthood. Identifying the earliest antecedents of persisting emotional and behavioral dysregulation can inform risk detection practices and targeted interventions to promote adaptive developmental trajectories among at-risk children.

OBJECTIVE: To characterize children's emotional and behavioral regulation trajectories and examine risk factors associated with persisting dysregulation across early childhood.

DESIGN, SETTING, AND PARTICIPANTS: This cohort study examined data from 20 United States cohorts participating in Environmental influences on Child Health Outcomes, which included 3934 mother-child pairs (singleton births) from 1990 to 2019. Statistical analysis …

Psychology University Students’ Mental Health Status During Covid-19 Pandemic In Karachi, Pakistan, Aisha Noorullah, Mubarak Mansoor, Ayesha Zahid

Department of Psychiatry

Purpose: The COVID-19 pandemic has brought challenges in various domains of life but for low and middle-income country university students very demanding situations have emerged. University students’ psychological well-being has always been an area of concern worldwide and higher rates of anxiety and depression have been extensively reported among this cohort.
Objective: To determine the frequency of depressive symptoms, anxiety symptoms, and quality of sleep and the association of sleep quality and personality traits with anxiety and depressive symptoms among university students in Karachi, Pakistan in the context of the pandemic COVID-19.
Method: This web-based cross-sectional study was conducted among …

Covid-19, Olfactory Functioning, And Depressive Symptoms, Kevin Davis Psy.D.

Dissertations

The focus in this study was to investigate whether people who continue to experience a disordered sense of smell after recovering from COVID-19 are more likely to have higher levels of depressive symptoms. Data collection involved two questionnaires: the Patient Health Questionnaire-9 (PHQ-9) to assess depressive symptoms and the Assessment of Self-Reported Olfactory Functioning and Olfaction-Related Quality of Life (ASOF) to assess olfactory functioning. Additionally, general survey questions were asked to evaluate physical and mental health outcomes related to COVID-19. Results showed individuals who did not subjectively return to their baseline sense of smell after recovering from COVID-19 had lower …

Implementation Of Collaborative Care Intervention Within A Fqhc To Achieve Uniform Data System (Uds) Measure Of Depression Remission, Rasha A. Kafi Msn, Rn, Fnp-C

Doctor of Nursing Practice Projects

Background: Depression is one of the most common and treatable mental health conditions. Untreated depression causes emotional suffering, reduced productivity, lost wages, increased comorbidity risks, and increased healthcare costs.

Purpose: The purpose of this project was to implement Collaborative Care Interventions (CCI) to achieve the Uniform Data System (UDS) Measure of Depression Remission.

Aims: The AIMS of this project were: (a) Increases the percentage of nursing staff compliance and completion of the educational training; (b) increases nursing staff knowledge of recognition of depression signs and symptoms, early identification of depression, and administration to all adult patients; (c) Increase the percentage …

The Effectiveness Of The Gut-Brain-Axis Versus Ssri For Treatment And Management Of Depression, Jenni Hetletved

Physician Assistant Scholarly Project Posters

Major Depressive Disorder (MDD) is a crippling condition that affects millions of people worldwide. Serotonin reuptake inhibitors (SSRIs) are the staple treatment adjunct to psychotherapy. Recently, the connection between gut health, specifically the gut brain axis, has been researched to look at the connection between gut microbiota and its effect on depressive symptoms. This meta-analysis evaluates the connection between gut microbiota and depression as well as the effectiveness of SSRI therapy on depression. Results show a significant change in gut microbiota with short term change to a Mediterranean diet (MD) compared to a Western diet (WD). This change in gut …

Cognitive Behavior Therapy Versus Internet Cognitive Behavior Therapy In Adults With Anxiety Or Depression, Heather Greenwood

Physician Assistant Scholarly Project Posters

According to the American Psychiatric Association, the prevalence of anxiety and depression in adults in their lifetime are nearly 30% and 16.6% respectively. The combination of pharmacotherapy and psychotherapy interventions (including talk therapy or cognitive behavior therapy (CBT)) are considered best practice, but in recent years there has been an increase in the popularity of applications and web-based services categorized as “internet cognitive behavior therapy”, or ICBT. The question proposed is, are these services as good for patient outcomes as traditional in-person CBT? A literature review was performed using electronic medical database PubMed with key word searches for cognitive behavior …

Gender As An Environmental Stressor In Individuals Genetically Predisposed To Mood Disorders: A Preliminary Analysis, Kara West

Audre Lorde Prize

Given the recent ‘epidemic’ of mental health disorders, we urgently need to better understand who is suffering and how. One aspect of this that research has come closer to identifying is where symptoms and diagnoses are missed in certain individuals, especially based on gender. However, if certain genders are actually more likely to deal with certain disorders we need to understand why and where that comes from. There is a general consensus in the medical field that some individuals are simply genetically predisposed to various disorders based on sex, but there is limited evidence that sex actually determines genetic predisposition. …

The Musical Touch On Mental Illness, Skylar Dunn

Senior Honors Theses

To understand the relationship amongst anxiety, depression, and music therapy, this integrative review synthesizes the major themes and relevant education of articles discussing mental health and the benefit of music. While most existing studies focus on using music therapy to treat pain and clinical anxiety, the content of this paper is written to emphasize how the same principles can be used in unmanageable stress and emotional decomposition. Each topic is analyzed and reviewed individually, pooling several sources for a thorough examination, and understanding of the subject. Once each area is fully summarized, the gap is addressed by pulling evidence from …

Examining Associations Between Social Needs And Mental Health Among Youth And Young Adults With Diabetes, Andrea Danielle Brown

Theses and Dissertations

Household food insecurity (HFI) disproportionally affects people with diabetes living in the United States and is more likely to occur in households with children and in minority race/ethnicity households. Food insecure people with youth-onset diabetes likely have increased risk for poor mental health due to dealing with stress and cost related to diabetes management, especially if facing additional health-related social needs that intersect with HFI. If left untreated, poor mental health among youth and young adults (YYA) with diabetes can lead to diabetes-related complications, increased health care costs, and mortality. Yet few studies have examined associations between HFI and mental …

Exploration Into The Relationship Between Colitis And Depression: A Potential Role For The Aryl Hydrocarbon Receptor, Kasie Lynn Roark

Theses and Dissertations

Inflammatory Bowel Disease (IBD) is a group of chronic gastrointestinal disorders with unclear etiology comprised of two defined disorders – Crohn’s Disease (CD) and Ulcerative Colitis (UC). IBD leads to chronic pain, socially isolating symptoms, and an overall reduction in patient quality of life. There is currently no cure for IBD. Due to decreased mucous production and weakening of the colonic epithelial lining, gut-microbiota and their metabolites can invade the intestinal lamina propria and circulate systemically, a term known as “leaky gut”. Recent studies show a relationship exists between peripheral inflammation, such as IBD, and depression. The gut-brain axis (GBA) …

Exercise And Mental Health Over The Course Of A Semester, Jamie Alexis Whitney

Theses and Dissertations

Introduction and purpose: Anxiety and depression are two of the most common mental health struggles in the United States each year. There has been promising research noting the positive effects of exercise on lowering symptoms of both anxiety and depression. Anxiety and depression are highly prevalent on college campuses, especially during high stress portions of the semester. The purpose of this study was to observe the changes in mental health over the course of the semester and if exercise level mediated any of these changes in the university population. Methods: Participants scanned a QR code or followed a link to …

Covid-19 Lockdown: Impact On College Students’ Lives, Wendy C. Birmingham, Lori L. Wadsworth, Jane H. Lassetter

Faculty Publications

Objective: In light of COVID-19, leaders issued stay-at-home orders, including closure of higher-education schools. Most students left campus, likely impacting their employment and social network. Leaders are making decisions about opening universities and modality of instruction. Understanding students' psychological, physiological, academic, and financial responses to the shut-down and reopening of campuses can help leaders make informed decisions. Participants: 654 students from a large western university enrolled during the pandemic shutdown. Methods: Students were invited via email to complete an online survey. Results: Students reported stress, depression, loneliness, lack of motivation, difficulty focusing on schoolwork, restless sleep, appetite changes, job loss …

Psychiatric Consequences Of Hospitalized Covid-19 Patients In Iraq: A Preliminary Report, Hussein Meften, Rafid Al Zaidy, Marwa Ahmed, Lubna Naji, Mushtaq Hashim, Nesif Al Hemiary, Jawad Al-Diwan

Iraqi Postgraduate Medical Journal

ABSTRACT:BACKGROUND:World Health Organization (WHO) termed coronavirus disease 2019 COVID-2019, then declared it as a pandemic. It was documented that survivors of COVID-19 were at risk of developing anxiety, depression, and insomnia. This study was carried out to report on prevalence of psychiatric symptoms and identifying some determinants.PATIENTS AND METHODS:A total of 120 patients with COVID-19 were included in this study. Their age was 22 to 91 years giving male to female ratio of 1.6:1. They were selected conveniently (they were hospitalized in  Al-Shafa center). The hospital anxiety and depression scale was used.RESULTS:Out of the total, 66% and 52.9% were showing …

Prevalence And Trends Of Depression Among Cyberbullied Adolescents - Youth Risk Behavior Survey, United States, 2011 – 2019, Jason Nicholson, Catherine Marcum, George E. Higgins

International Journal of Cybersecurity Intelligence & Cybercrime

The difference in depression between non-cyberbullied and cyberbullied youth is not well understood. To describe the prevalence and trends in depression among cyberbullied adolescents. Using cross-sectional, nationally-representative data from the YRBS 2011 - 2019, we estimated the prevalence and trends of depression across the total years and within cyberbullied groups that include biological sex and race and ethnicity among adolescents. The results indicated the prevalence of depression was higher among those that were cyberbullied. Within the cyberbullied groups the total trend was higher than the non-cyberbullied, females had a higher prevalence of depression than males, and Hispanics had a higher …

Towards Scalable Mental Health: Leveraging Digital Tools In Combination With Computational Modeling To Aid In Treatment And Assessment Of Major Depressive Disorder, Matthew D. Nemesure

Dartmouth College Ph.D Dissertations

Major depressive disorder (MDD) is a debilitating disorder that impacts the lives of nearly 280 million individuals worldwide, representing 5% of the overall adult population. Unfortunately, these statistics have been both trending upward and are also likely an underestimate. This can be primarily attributed to lack of screening paired with a lack of providers. Worldwide, there are roughly 450 individuals living with MDD per mental health care provider. Adding to this burden, approximately half of affected individuals that do receive care of any kind will fail to remain in remission. The goal of this thesis work is to leverage statistical …

Liberating Self: An Autoethnographic Inquiry Into Black Male Mental Health, Phillip J. Roundtree Sr.

Social Work Doctoral Dissertations

This autoethnography offers a first-person perspective on Black male mental health experiences. It incorporates personal narratives and academic research to explore the intersectionality of race, gender, and mental health, as well as the impact of historical and contemporary systemic racism and discrimination on Black males' psychological and emotional well-being.

The Black Liberation Psychology theoretical framework and Africana Studies Conceptual framework examined how cultural norms, hip-hop culture, stigma, and societal factors, including racism, discrimination, and stereotypes about Black masculinity, shape Black male mental health experiences. The study also highlights Black males' development of coping mechanisms and resilience strategies to navigate these …

The Nrf2 Pathway In Depressive Disorders: A Systematic Review Of Animal And Human Studies, Ottavia Marianna Ferrara, Evelina Bernardi, Alessio Simonetti, Laura Monti, Marianna Mazza, Delfina Janiri, Lorenzo Moccia, Georgios D Kotzalidis, Daniela Pia Rosaria Chieffo, Luigi Janiri

Faculty, Staff and Students Publications

There is increasing interest in the involvement of antioxidative systems in protecting from depression. Among these, Nrf2 occupies a central place. We aimed to review the role of Nrf2 in depression. For this reason, we conducted a PubMed search using as search strategy (psychiatr*[ti] OR schizo*[ti] OR psychot*[ti] OR psychos*[ti] OR depress*[ti] OR MDD[ti] OR BD[ti] OR bipolar[ti] OR Anxiety[ti] OR antidepress*[ti] OR panic[ti] OR obsess*[ti] OR compulsio*[ti] OR “mood disord*”[ti] OR phobi*[ti] OR agoraphob*[ti] OR anorex*[ti] OR anorect*[ti] OR bulimi*[ti] OR “eating disorder*”[ti] OR neurodevelopm*[ti] OR retardation[ti] OR autism[ti] OR autistic[ti] OR ASM[ti] OR adhd[ti] OR “attention-deficit”[ti]) AND nrf2, …

Psychosocial Predictors Of Early Postpartum Depressive And Anxious Symptoms In Primiparous Women And Their Partners., Erin J Henshaw, Marie Cooper, Teresa Wood, Stacey N Doan, Sanchita Krishna, Marie Lockhart

OhioHealth Research Institute Articles

BACKGROUND: While the majority of research on postpartum depressive and anxious symptoms has focused on mothers, a growing body of research suggests a need to understand the role of the partner's health and relationship quality as predictors of postpartum maternal depression, while also better understanding correlates of partner or paternal depression in the postpartum period. The purpose of the current study is to evaluate mother and partner stress, anxiety, mood, infant care support, and relationship quality as predictors of perinatal depressive and anxious symptoms in first time mothers and partners during the postpartum hospital stay.

METHODS: First time parent couples …

Autistic Masking, Joshua Evans, Thalia Markowski, Steven V. Rouse Dr., Elizabeth J. Krumrei-Mancuso Dr.

Seaver College Research And Scholarly Achievement Symposium

This study investigated the relationships between autistic masking and depression, anxiety, gender identity, sexual orientation, social trauma, self-esteem, authenticity, and autistic community involvement. Participants were autistic adults (n=342) recruited through autistic social media groups. The majority of participants (63%) reported being members of sexual minorities. The study found higher self-reported autistic masking behaviors were associated with higher reports of past social trauma (p < .001, b = .26), greater anxiety (p < .001, b = .37) and depression symptoms (p < .001, b = .312), lower self-esteem (p < .001, b = -.25), lower authentic living (p = .005, b = -.16), greater accepting of external influence (p < .001, b= .33), higher self-alienation (p < .001, b = .26), and lower participation within the autistic community (p < .001, b = -.19). Autistic masking was not found to be associated with gender identity or sexual orientation. Participants who reported involvement in previous ABA therapy reported higher past social trauma than participants involved in some other forms of therapy such as cognitive behavior therapy.

Antidepressant Augmentation Versus Switch In Treatment-Resistant Geriatric Depression, Eric J Lenze, Pilar Cristancho, Torie R Gettinger, Emily Lenard, J Philip Miller, Ginger E Nicol, Vy T Pham, Lei Yang, Et Al.

2020-Current year OA Pubs

BACKGROUND: The benefits and risks of augmenting or switching antidepressants in older adults with treatment-resistant depression have not been extensively studied.

METHODS: We conducted a two-step, open-label trial involving adults 60 years of age or older with treatment-resistant depression. In step 1, patients were randomly assigned in a 1:1:1 ratio to augmentation of existing antidepressant medication with aripiprazole, augmentation with bupropion, or a switch from existing antidepressant medication to bupropion. Patients who did not benefit from or were ineligible for step 1 were randomly assigned in step 2 in a 1:1 ratio to augmentation with lithium or a switch to …

The Relationship Among Depression, Motivational Factors, And Diabetes Management In Emerging Adults With Type 1 Diabetes, Sahar Elmenini, April Idalski Carcone, Deborah Ellis

Medical Student Research Symposium

Self-determination theory (SDT) posits intrinsic motivation arises from fulfilling three psychological needs – autonomy, self-efficacy, and relatedness. SDT is useful for understanding the challenges emerging adults (EA, age 18-30) living with a chronic illness, like type 1 diabetes (T1D), face including developing independence, autonomy and new relationships while parental support and involvement decrease. This places EAs at risk for sub-optimal health. Depression can further decrease motivation. The aim of this study is to test the hypothesis that depressive symptoms are associated with motivation (autonomy and self-efficacy) which are associated with diabetes management (DM) in EAs with T1D. Participants (N=52) were …

Replacing Adjunctive Medications For Treatment-Resistant Depression Using Repetitive Transcranial Magnetic Stimulation: Case Report, Anita Vaishampayan Bs, Bassem Saad Md, Daniel Amarasinghe Bs, Carly Brin Lmsw, Richard Balon Md, Nicholas Mischel Mdphd

Medical Student Research Symposium

Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for depression. As the left prefrontal cortex activity is linked to depression, rTMS induces blood flow in the left dorsolateral prefrontal cortex (dlPFC). Long acting psychostimulants are sometimes prescribed as an adjunctive antidepressant treatment throughout rTMS therapy. We used rTMS to treat resistant depression in a middle-aged male patient over a twelve month period where a psychostimulant medication was also discontinued. He had been consistently taking duloxetine 60 mg BID, clonazepam 0.5 mg BID, and dextroamphetamine-amphetamine extended release 30 mg once daily prior to the onset of rTMS treatment. The patient …

A Participatory Study Of College Students’ Mental Health During The First Year Of The Covid-19 Pandemic, Chulwoo Park, Melissa Mcclure Fuller, Thea Marie Echevarria, Kim Nguyen, Daisy Perez, Hufsa Masood, Tasneem Alsharif, Miranda E. Worthen

Faculty Research, Scholarly, and Creative Activity

Introduction: The COVID-19 pandemic has negatively impacted college students’ mental health and wellbeing. Even before the pandemic, young adults reported high mental health morbidity. During the pandemic, young adult college students faced unprecedented challenges, including campus closure and a pivot to fully online education.

Methods: This study employed a novel participatory approach to a Course-based Undergraduate Research Experience (CURE) in an introductory epidemiology course to examine factors students considered important regarding their experience during the pandemic. Two groups of undergraduate students enrolled in this course (one in Fall 2020 and another in Spring 2021) and participated in the CURE. A …

The Influence Of Child Maltreatment In The Manifestation Of Anxiety And Depressive Symptoms At The Age 18, Maria J. Velasquez

LSU Master's Theses

Child maltreatment affects thousands of children and adolescents every year. This phenomenon is multidimensional, meaning there are different subtypes (i.e., physical abuse, sexual abuse, emotional abuse, and neglect) known to predict various mental health issues, including depression and anxiety. While previous research has investigated mental health outcomes in maltreated youth, results may vary based on the dimensions of abuse considered. This study aims to expand on previous literature to examine how a history of child maltreatment subtypes influences the manifestation of anxiety and depressive symptoms in youth at age 18. The current study uses secondary data analysis of the Longitudinal …

Acupuncture Treatment For Post-Stroke Depression: Intestinal Microbiota And Its Role, Hailun Jiang, Shizhe Deng, Jieying Zhang, Junjie Chen, Boxuan Li, Menglong Zhang, Zhihong Meng

Faculty, Staff and Student Publications

Stroke-induced depression is a common complication and an important risk factor for disability. Besides psychiatric symptoms, depressed patients may also exhibit a variety of gastrointestinal symptoms, and even take gastrointestinal symptoms as the primary reason for medical treatment. It is well documented that stress may disrupt the balance of the gut microbiome in patients suffering from post-stroke depression (PSD), and that disruption of the gut microbiome is closely related to the severity of the condition in depressed patients. Therefore, maintaining the balance of intestinal microbiota can be the focus of research on the mechanism of acupuncture in the treatment of …