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Non-Compliance To Social Distancing During Covid-19 Pandemic: A Comparative Cross-Sectional Study Between The Developed And Developing Countries, Faiqa Binte Aamir, Syeda Maria Ahmad Zaidi, Saadia Abbas, Syed Roohan Aamir, Syed Nauman Ahmad Zaidi, Karishma Kanhya Lal, Syeda Sadia Fatima

Medical College Documents

Background: Despite mass vaccination campaigns, the world has seen a steady rise in the number of SARS-CoV-2 cases, with 178,765,626 cases and 3,869,994 COVID-19 related deaths by June 19^th, 2021. Therefore, it is important to enforce social distancing to control its spread. With the variation observed in the severity of the pandemic in different countries, it is also imperative to study the social distancing behaviors amongst the population in developed and developing countries.
Design and Methods: In this cross-sectional study, a total of 384 participants from 14 different countries were surveyed via an online REDCap form.
Results: In …

Laboratory Diagnostic Testing For Covid-19, Nuntra Suwantarat, Sidayu Suriya

Asian Medical Journal and Alternative Medicine

Laboratory tests play an important role for Corona Virus Disease 2019 (COVID-19) diagnosis. The diagnostic key point is an appropriate testing during the course of disease. In the early course of COVID-19 infection, nucleic acid amplification tests (NAATs) especially real-time reverse-transcription polymerase chain reaction (RT-PCR) of the respiratory specimen is the gold standard test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection due to the highest sensitivity and specificity during the first 2 weeks after the exposure. A rapid antigen test for SARS-CoV-2 has less complexity of the testing procedure and the faster TAT. However, a rapid antigen test …

Gastrointestinal And Liver Manifestations Of Covid-19, Keerati Kiattikunrat, Sith Siramolpiwat

Asian Medical Journal and Alternative Medicine

Almost every country in the world has been affected by the pandemic of Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first reported in Wuhan, China, in December 2019. The clinical manifestation is diverse, ranging from asymptomatic to severe pneumonia requiring mechanical ventilation. In addition, gastrointestinal symptoms have also been reported to occur during the course of the disease. In some patients, gastrointestinal symptoms may precede respiratorytract symptoms. Interestingly, the SARS-CoV-2 RNA could be detected in the stool of COVID-19 patients, implying that SARS-CoV-2 may be transmitted by fecal-oral route. Moreover, mild transient abnormal liver …

Covid-19 In Children, Pornumpa Bunjoungmanee, Detchvijitr Suwanpakdee

Asian Medical Journal and Alternative Medicine

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a pandemic in many countries necessitating the employment of massive public health responses. Clinical manifestations of children with COVID-19 are typically less severe than adult patients. Most children with COVID-19 remain asymptomatic or become mildly symptomatic. However, children can also get severely ill from COVID-19. Infants who are under the age of one year and children with preexisting comorbidities may be more likely to develop severe illness and are at an increased risk for hospitalization and critical care. Rarely, COVID-19 may result in multisystem inflammatory syndrome …

Covid-19 And Neurology, Sombat Muengtaweepongsa, Vatcharasorn Panpattanakul

Asian Medical Journal and Alternative Medicine

The coronavirus 2019 (COVID-19) infection initially affects the respiratory system. However, nervous system involvement lately becomes a significant feature of COVID-19 infection. The neurologic manifestations can be direct and indirect viral effects or just the non-specific complications from critical illness. The prevalence of stroke in patients with COVID-19 is higher than in other viral infections. COVID-19 patients with stroke have a high mortality rate. Central nervous system involvement with alteration of consciousness commonly occurs in hospitalized patients with COVID-19. As well as any other viruses, COVID-19 infection may likely be antecedent to Guillain Barre Syndrome. COVID-19 vaccination may cause neurological …

Current And Repurposing Medication For Sars-Cov-2 Infection, Kittiya Jantarathaneewat, Korakoch Kangwantas, Nattapong Tidwong

Asian Medical Journal and Alternative Medicine

In the crisis of COVID-19 pandemic, there is no specific agent to treat SARS-CoV-2 infection. Repurposing medication can be an alternative agent. Remdesivir is the first antiviral drug that has been approved for COVID-19 treatment whereas lopinavir/ritonavir and hydroxychloroquine, which was early used in SARS-CoV-2 widespread, are against by well-known guidelines due to lack of efficacy and potential toxicity. Corticosteroids are an essential supportive care in COVID-19 patient with severe disease to reduce lung inflammation. Favipiravir may have a potential benefit for COVID-19 patient, but the data is still uncertain. Ivermectin, an antihelmintic agent, may be used against SARS-CoV-2 but …

Digital Technology And Disease Surveillance In The Covid-19 Pandemic: A Scoping Review Protocol, Lorie Donelle Phd, Rn, Fcan, Jodi Hall, Brad Hiebert, Jacob J. Shelley, Maxwell J. Smith, Jason Gilliland, Saverio Stranges, Anita Kothari, Jacquelyn Burkell, Tommy Cooke, Jed Long, James M. Shelley, Deanna Befus, Leigha Comer, Marionette Ngole, Meagan Stanley

Publications

INTRODUCTION: Infectious diseases pose a risk to public health, requiring efficient strategies for disease prevention. Digital health surveillance technologies provide new opportunities to enhance disease prevention, detection, tracking, reporting and analysis. However, in addition to concerns regarding the effectiveness of these technologies in meeting public health goals, there are also concerns regarding the ethics, legality, safety and sustainability of digital surveillance technologies. This scoping review examines the literature on digital surveillance for public health purposes during the COVID-19 pandemic to identify health-related applications of digital surveillance technologies, and to highlight discussions of the implications of these technologies. METHODS AND ANALYSIS: …

Covid-19 Treatment, Suttichai Visuttichaikit

Asian Medical Journal and Alternative Medicine

The ongoing outbreak of COVID-19 has posed a great threat to public health. The various degree and dynamic of illness severity, together with the fact that only few drugs have been proven as an effective therapy has created critical challenges in disease management. Patients in acute viral phase usually present with upper respiratory tract and/or gastrointestinal illness, fever, and myalgia. Antiviral therapy might provide the greatest benefit in reducing disease progression in such patients with older age or significant comorbidities while immunomodulators are less likely to provide advantages. Patients in immune dysregulation phase usually present with pneumonia of different severity. …

Covid-19 And Pulmonary Involvement, Narongkorn Saiphoklang, Nuttapol Rittayamai

Asian Medical Journal and Alternative Medicine

The COVID-19 pandemic results in the largest global health crisis. Most patients are asymptomatic. Pneumonia usually develops in about one week after infection, with approximately 5% of patients needing ICU admission due to hypoxemia or acute respiratory failure. The common symptoms of patients with COVID-19 pneumonia are fever, cough, and sputum production. Typical radiographic features of pneumonia are bilateral lower lobe lesions with ground-glass opacities or consolidations. N95 respirator in combination with personal protective equipment are necessary to prevent COVID-19 from spreading among healthcare workers during aerosol-generating procedures. Hemodynamic and ventilation management of critically ill patients with COVID-19 should follow …

Data-Driven Transmission Patterns Of Covid-19 In Asean+6, Panyawut Sri-Iesaranusorn, Amornpong Trakarnkulphun, Attawit Chaiyaroj, Decho Surangsrirat

Asian Medical Journal and Alternative Medicine

Introduction: Our objective is to discover transmission patterns of COVID-19 in the group of 16 countries called ASEAN+6 which comprise the ten countries in ASEAN and China, Japan, South Korea, Australia, New Zealand, and India.

Methods: The public dataset from John Hopkins University was used in this work. The concept of the effective reproduction number (ℛ) based on the SIR model is used to define the wave of infection. K-means clustering, an unsupervised machine learning algorithm, is then applied to the time-series data to divide the waves into clusters.

Results: The data of the confirmed cases and fatalities were separated …

Covid-19 Disease And Viral Characteristics In A Long-Term Care Facility, Shauna Assadzandi, Emily Crocetti, Courtney S. Pilkerton, Amie M. Ashcraft, Carl D. Shrader

Marshall Journal of Medicine

Background

Due to the combination of age, comorbidities, and close living quarters, residents at long-term care facilities (LTCFs) are at particularly high risk of severe symptoms and death due to COVID-19.

Methods

This cross-sectional study examines the relationship between demographic characteristics, symptom severity, and length of viral shedding in 49 residents testing positive for SARS-CoV-2 at a LTCF in West Virginia (WV).

Results

Over half of the residents were asymptomatic, while nearly a quarter experienced severe symptoms. Women were more likely to be asymptomatic, and age was not associated with symptom severity. While no specific medical condition was associated with …

Colchicine, Covid-19 And Hematological Parameters: A Meta-Analysis, Musharraf Sarwar, Zahid Ali, Mahnoor Fatima, Zouina Sarfraz, Azza Sarfraz, Ivan Cherrez-Ojeda

Department of Paediatrics and Child Health

Introduction: Colchicine has the potential in reducing patient morbidity and mortality in COVID-19 infection owing to its anti-inflammatory properties. This study aims to determine the efficacy of colchicine in optimizing inflammatory hematological biomarker levels among COVID-19 patients.
Methods: In accordance to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 statement guidelines, a systematic search was conducted using the following keywords: Colchicine, covid*, SARS-CoV-2, anti-inflammatory, trials, clinical, hematological, laboratory. Databases were searched from December 2019 until August 26, 2021: MEDLINE/PubMed, Web of Science, Cochrane, Scopus, and EMBASE. Other sources were located through ClinicalTrials.Gov, manually searching SAGE, Science Direct, Elsevier, …

Covid-19 In Patients With Hematologic Malignancies: A Single Center Retrospective Study, Xuejun Wang, Adam Binder, Usama Gergis, Lindsay Wilde, Md

Department of Medical Oncology Faculty Papers

Initial studies that described the novel coronavirus (COVID-19) reported increased morbidity and mortality in patients with cancer. Of this group, patients with hematologic malignancies (HM) had the highest disease severity and death rates. Subsequent studies have attempted to better describe how COVID-19 affects patients with HM. However, these studies have yielded variable and often contradictory results. We present our single-institution experience with patients with HM who were diagnosed with COVID-19 from March 2020 to March 2021. We report 62 total cases with 10 patients who died during this time. The overall mortality was 16.1%. Mortality during the first two waves …

Reifying Anderson-Burdick: Voter Protection In The Time Of Pandemic And Beyond, Keeley Gogul

University of Cincinnati Law Review

No abstract provided.

Saving The Nonessential With Radical Tax Policy, Rodney P. Mock, Kathryn Kisska-Schulze

University of Cincinnati Law Review

Under the Internal Revenue Code of 1986, as amended, for-profit entities are distinguishable from tax-exempt entities in that they, among other factors, pursue profits, and enjoy unrestricted commercial activities. The COVID-19 lockdowns prevented commercial activity for numerous for-profit small businesses. For the first time in United States history, a distinction was made between "essential" and "nonessential" businesses. Such distinction is historically absent in both legal scholarship and tax law; instead, it is a product of governmental reaction to the COVID-19 pandemic. Via executive order, nonessential businesses were characterized as being trivial to the fabric of society, and thus shuttered, while …

When The Conditions Are The Confinement: Eighth Amendment Habeas Claims During Covid-19, Michael L. Zuckerman

University of Cincinnati Law Review

The COVID-19 pandemic cast into harsher relief much that was already true about mass incarceration in the United States. It also cast into harsher relief much that was already true about the legal barriers confronting people seeking to make its conditions more humane. This Article offers a brief overview of the legal landscape as the COVID-19 crisis arose and then surveys eight prominent federal cases involving Eighth Amendment claims related to COVID-19 outbreaks at carceral facilities, most of which included significant litigation over whether they could secure release through habeas corpus. The Article then distills six key tensions from these …

Exploring Online Participatory Theatre During Covid-19: Reflections On Adapting, Delivering, And Evaluating Student-Led Theatre For Health Workshops, Jeffrey Pufahl, Emmanuelle Crider, Kelviyana Walker

Spect-actor: A Journal of Pedagogy & Theatre of the Oppressed

The COVID-19 pandemic forced the higher education community to quickly shift and adapt courses to the online environment. While traditional theatre programs struggled, the flexible nature of applied theatre created the space for students and instructors to explore and adapt existing forms, such as Forum Theatre and Sociodrama, and create engaging online workshops for the public. Over the course of 2020-21, students in the University of Florida’s Applied Theatre for Health program developed, delivered, and evaluated online health and wellness workshops for the public. This report focuses on two such projects: 1) a workshop on female reproductive health, and 2) …

2021-10-27_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

Faculty Perceptions Of The Exercise Science Student Learning Experience During The Coronavirus Pandemic, Jennifer Caputo, Astrid E. Mel, Mary C. Stenson, Jessica K. Fleming, Samantha L. Jonson, Katherine E. Spillios

Exercise and Health Science Faculty Publications

Significant disruptions in higher education course delivery occurred during the coronavirus (COVID-19) global pandemic. The implementation of emergency remote teaching (ERT) offered exercise science faculty a safe method to continue educating students in courses generally taught face-to-face. The purpose of this investigation was to explore faculty perceptions of their ERT efforts with respect to student successes, challenges, and faculty expectations. Through an electronic survey, participants (n = 112) from higher education institutions in 31 states and three Canadian provinces provided feedback on their perceptions of the student experience across 315 fall 2020 courses. Data analysis included a thematic analysis …

2021-10-27_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. COVID case and testing data will be posted three times a week on Mondays, Wednesdays and Fridays.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time …

Nebulization Of Low-Dose S-Nitrosoglutathione In Diabetic Stroke Enhances Benefits Of Reperfusion And Prevents Post-Thrombolysis Hemorrhage, Syed Kashif Zaidi, Farid Ahmed, Heba Alkhatabi, Nasrul Hoda, Muhammad Al-Qahtani

Neurology Articles

The COVID-19 pandemic has escalated the occurrence of hypoxia including thrombotic stroke worldwide, for which nitric oxide (NO) therapy seems very promising and translatable. Therefore, various modes/routes of NO-delivery are now being tested in different clinical trials for safer, faster, and more effective interventions against ischemic insults. Intravenous (IV) infusion of S-Nitrosoglutathione (GSNO), the major endogenous molecular pool of NO, has been reported to protect against mechanical cerebral ischemia-reperfusion (IR); however, it has been never tested in any kind of "clinically" relevant thromboembolic stroke models with or without comorbidities and in combination with the thrombolytic reperfusion therapy. Moreover, "IV-effects" of …

The State Of The Hospitality Industry 2021 Employment Report: Covid-19 Labor Force Legacy, Robertico R. Croes, Kelly Semrad, Manuel A. Rivera

Dick Pope Sr. Institute Publications

The purpose of this study is to investigate the COVID-19 pandemic's ongoing impact on the U.S. hospitality industry. The report details the primary economic issues the industry faces as well as provides a unique workforce analysis that anticipates continued labor shortages as the country moves towards an endemic. The research was conducted using a national survey with almost 1,000 U.S. hospitality workers. The survey includes questions pertaining to COVID-19 related hospitality employee topics such as: the impact COVID-19 had on hospitality jobs, employees' intentions to leave the industry, employees likelihood to accept or look for a hospitality job, employees' perceived …

Sources Of Distress And Coping Strategies Among Emergency Physicians During Covid-19, Erin Dehon, Kori S. Zachrison, Jennifer M. Peltzer-Jones, Ramin R. Tabatabai, Elizabeth Clair, Michael A. Puskarich, Amy Ondeyka, Katherine Dixon-Gordon, Lauren A. Walter, Elaine H. Situ-Lacasse, Megan L. Fix

Emergency Medicine Articles

INTRODUCTION: The coronavirus disease 2019 (COVID-19) pandemic has been shown to increase levels of psychological distress among healthcare workers. Little is known, however, about specific positive and negative individual and organizational factors that affect the mental health of emergency physicians (EP) during COVID-19. Our objective was to assess these factors in a broad geographic sample of EPs in the United States.

METHODS: We conducted an electronic, prospective, cross-sectional national survey of EPs from October 6-December 29, 2020. Measures assessed negative mental health outcomes (depression, anxiety, post-traumatic stress, and insomnia), positive work-related outcomes, and strategies used to cope with COVID-19. After …

Unh Students, Administration Discuss ‘Sick Days’ During The Pandemic, Anna Kate Munsey

Digital Edition

An independent student produced newspaper from the University of New Hampshire.

Twenty Years After The Anthrax Terrorist Attacks Of 2001: Lessons Learned And Unlearned For The Covid-19 Response, Lawrence O. Gostin, Jennifer B. Nuzzo

Georgetown Law Faculty Publications and Other Works

The 20th anniversary of the terrorist attacks on September 11, 2001, resulted in deep national reflection. Less remembered are the events that began to unfold 7 days later as anonymous letters laced with deadly anthrax (Bacillus anthracis) spores began arriving at postal facilities, media companies, and congressional offices. The first death from inhaled anthrax exposure occurred on October 5, with an additional 4 deaths and 17 infections over the ensuing months.

The anthrax attacks exposed a health system ill-equipped to respond to acute emergencies. This article explores the lessons learned, and unlearned, from the anthrax attacks, through to …

Re-Imagining The Boundaries: Transforming An Annual Reception Due To Covid-19, Ruth Monnier, Chris Labuda, Jorge Leon, Robert Lindsey

Faculty Submissions

How do you reimagine an over 30-year annual event in the world of COVID-19? Pittsburg State University (PSU) Library Services needed to transform their longest ongoing traditional program, University Authors Reception, in 2020. This event honors authors and creators at PSU by showcasing their publications from the year. Traditionally, this celebration allowed for the honorees and community to engage in discussion about their works, enjoy light refreshments, and celebrate their accomplishments with family and friends. With the uncertainty of COVID-19 and related safety protocols, PSU librarians took the opportunity to reshape elements of the event to ensure a focus on …

2021-10-26_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173-526911--,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data for all reporting facilities is posted weekly each Monday.

The information below represents COVID-19 data reported directly to MDHHS by licensed and operating Skilled Nursing, Home for the Aged and Adult Foster Care facilities (licensed to serve 13 or more individuals) in Michigan from January 1, 2020. All long-term care facilities additionally have an obligation to report COVID-positive residents and/or staff …

2021-10-26_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated three times a week on Mondays, Wednesdays and Fridays.

Syndromic Surveillance System data is obtained from approximately 216 facilities participating in syndromic surveillance (139 Emergency Departments (ED), 77 Urgent Care) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, …

Case Series: Demonstration Of The Criticality Of Early Identification For Vestibular Labyrinthitis, Taylor Schaul, Antony Joseph

AuD Capstone Projects - Communication Sciences and Disorders

Introduction: labyrinthitis occurs when both branches of the vestibulocochlear nerve swell, specifically the vestibular and cochlear portions. Diagnosed by the process of elimination, labyrinthitis can have detrimental auditory and vestibular effects when identified untimely. When diagnosed early, labyrinthitis can be resolved with rest, medication, and vestibular rehabilitation therapy. Case Presentation: A young adult presented to the clinic with a heavy head sensation, lack of concentration, and blurry vision that escalated to left ear fullness, unilateral tinnitus, and an untriggered persistent headache. Discussion: This patient was undiagnosed for three months due to the unavailability of vestibular testing in the emergency room …

Structural Mechanism Of Sars-Cov-2 Neutralization By Two Murine Antibodies Targeting The Rbd, John M Errico, Haiyan Zhao, Rita E Chen, Zhuoming Liu, James Brett Case, Meisheng Ma, Aaron J Schmitz, Michael J Rau, James A J Fitzpatrick, Pei-Yong Shi, Michael S Diamond, Sean P J Whelan, Ali H Ellebedy, Daved H Fremont

Open Access Publications

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has necessitated the rapid development of antibody-based therapies and vaccines as countermeasures. Here, we use cryoelectron microscopy (cryo-EM) to characterize two protective anti-SARS-CoV-2 murine monoclonal antibodies (mAbs) in complex with the spike protein, revealing similarities between epitopes targeted by human and murine B cells. The more neutralizing mAb, 2B04, binds the receptor-binding motif (RBM) of the receptor-binding domain (RBD) and competes with angiotensin-converting enzyme 2 (ACE2). By contrast, 2H04 binds adjacent to the RBM and does not compete for ACE2 binding. Naturally occurring sequence variants of SARS-CoV-2 and corresponding neutralization escape …