Digital Commons Network^™

Treatment Of Severe Covid-19 Infection With Remdesivir In Peritoneal Dialysis, Ryan Geffin, Shazia Raheem, Lavannya M Pandit, Andrew S Hunter, Michael W Holliday, Aditya V Rao, Maulin K Shah

Faculty, Staff and Students Publications

End-stage kidney disease (ESKD) has been shown to be correlated with an increased risk of COVID-19 infection and mortality. Remdesivir is an effective non-EUA U.S. Food and Drug Administration (FDA)-approved antiviral agent for the treatment of COVID-19 in hospitalized adult and pediatric patients, though a lack of data has prevented its use in patients with severe kidney disease including dialysis patients. Some observational studies report the use of remdesivir in hemodialysis patients, but there are no reports of patients treated with remdesivir on peritoneal dialysis. Dialysis modalities may affect drug pharmacokinetics, and safety and efficiency of remdesivir in peritoneal dialysis …

Physiologic Profile Associated With Severe Multisystem Inflammatory Syndrome In Children: A Retrospective Study, Fabio Savorgnan, Alvaro Moreira, Axel Moreira, Ananth Annapragada, S Kristen Sexson Tejtel, Saul Flores, Craig G Rusin, Lara Shekerdemian, Sebastian Acosta

Faculty, Staff and Students Publications

OBJECTIVE: The purpose of this study was to describe the clinical presentation and physiologic profile of individuals with varying degrees of severity of multisystem inflammatory syndrome in children (MIS-C).

METHODS: We performed a retrospective study of children diagnosed with MIS-C admitted to a single quaternary children's hospital from May 2020 to April 2021. We created an MIS-C severity score using the following parameters: hospital admission status (e.g., floor vs intensive care unit), need for inotropic or vasoactive medications, and need for mechanical ventilation. Univariate and multivariate analyses were performed to associate risk factors corresponding to the MIS-C severity score.

RESULTS: …

A Novel Interaction Between Extracellular Vimentin And Fibrinogen In Fibrin Formation, Marina Martinez-Vargas, Adrian Cebula, Lisa S Brubaker, Nitin Seshadri, Fong W Lam, Michele Loor, Todd K Rosengart, Andrew Yee, Rolando E Rumbaut, Miguel A Cruz

Faculty, Staff and Students Publications

INTRODUCTION: Thrombosis is frequently manifested in critically ill patients with systemic inflammation, including sepsis and COVID-19. The coagulopathy in systemic inflammation is often associated with increased levels of fibrinogen and D-dimer. Because elevated levels of vimentin have been detected in sepsis, we sought to investigate the relationship between vimentin and the increased fibrin formation potential observed in these patients.

MATERIALS AND METHODS: This hypothesis was examined by using recombinant human vimentin, anti-vimentin antibodies, plasma derived from healthy and critically ill patients, confocal microscopy, co-immunoprecipitation assays, and size exclusion chromatography.

RESULTS: The level of vimentin in plasma derived from critically ill …

What Can We Learn From Covid-19?: Examining The Resilience Of Primary Care Teams, Ashley M Hughes, Kelley Arredondo, Houston F Lester, Frederick L Oswald, Trang N D Pham, Cheng Jiang, Sylvia J Hysong

Faculty, Staff and Students Publications

INTRODUCTION: The COVID-19 pandemic continues to place an unprecedented strain on the US healthcare system, and primary care is no exception. Primary care services have shifted toward a team-based approach for delivering care in the last decade. COVID-19 placed extraordinary stress on primary care teams at the forefront of the pandemic response efforts. The current work applies the science of effective teams to examine the impact of COVID-19-a crisis or adverse event-on primary care team resilience.

METHODS: Little empirical research has been done testing the theory of team resilience during an extremely adverse crisis event in an applied team setting. …

Distinct Temporal Trajectories And Risk Factors For Post-Acute Sequelae Of Sars-Cov-2 Infection, Chen Chen, Sairam Parthasarathy, Jacqueline M Leung, Michelle J Wu, Katherine A Drake, Vanessa K Ridaura, Howard C Zisser, William A Conrad, Victor F Tapson, James N Moy, Christopher R Defilippi, Ivan O Rosas, Bellur S Prabhakar, Mujeeb Basit, Mirella Salvatore, Jerry A Krishnan, Charles C Kim

Faculty, Staff and Students Publications

BACKGROUND: The understanding of Post-acute sequelae of SARS-CoV-2 infection (PASC) can be improved by longitudinal assessment of symptoms encompassing the acute illness period. To gain insight into the various disease trajectories of PASC, we assessed symptom evolution and clinical factors associated with the development of PASC over 3 months, starting with the acute illness period.

METHODS: We conducted a prospective cohort study to identify parameters associated with PASC. We performed cluster and case control analyses of clinical data, including symptomatology collected over 3 months following infection.

RESULTS: We identified three phenotypic clusters associated with PASC that could be characterized as …

Unmet Needs And Coping Strategies Of Older Underserved Veterans During The Covid-19 Pandemic, Trenton M Haltom, Joyce Tiong, Tracy L Evans, Nipa Kamdar, Gala True, Mark E Kunik

Faculty, Staff and Students Publications

INTRODUCTION: The COVID-19 pandemic has had profound impacts on people with diabetes, a group with high morbidity and mortality. Factors like race, age, income, Veteran-status, and limited or interrupted resources early in the COVID-19 pandemic compounded risks for negative health outcomes. Our objective was to characterize the experiences and needs of under-resourced Veterans with type 2 diabetes during the COVID-19 pandemic.

METHODS: We conducted semi-structured qualitative interviews (March through September 2021) with U.S. military Veterans with diabetes. Transcripts were analyzed using a team-based, iterative process of summarizing and coding to identify key themes. Participants included Veterans (n = 25) who …

Contact-Tracing Apps As Boundary Objects Of Pandemic Governance: The State-By-State Approach To Contain The Spread Of Covid-19 In The United States, Eugene Jang, Jeeyun (Sophia) Baik, Katrin Fischer

Communication: Faculty Scholarship

Digital contact tracing has been claimed as imperative to controlling the spread of COVID19. However, the state-by-state approach in the United States led to divergences in contact tracing. This study analyzed contact-tracing apps as “boundary objects” through which each state worked toward the governance of the pandemic without having a formal consensus. Through media coverage and walkthrough analyses of three digital contacttracing apps in Alabama, California, and New York, we closely investigated both convergences and divergences of the apps. In the process, we located the implications of Google/Apple’s Bluetooth-based exposure notification system for digital contact tracing within and beyond state …

Delegitimizing Rural Public Health Departments: How Decaying Local News Ecologies, Misinformation, And Radicalization Undermine Community Storytelling Networks, Nik Usher

Communication: Faculty Scholarship

This article considers the public communication challenges that health officials in rural America faced during the COVID-19 pandemic. I analyze the role that public health officials played in communicating news and information about the pandemic in 29 rural counties in Illinois. These officials were challenged by a diminished reporting capacity among local media outlets, and by a political radicalization of local Republicans, who no longer regarded local media as trusted nodes in local storytelling networks. I find that while public health officials can help fill a community’s critical information needs about risk and emergency, the public’s take-up of this information …

Using Telemedicine And Telehealth To Extend Services In Hiv Care, Jeffery Dockery Mr., Heather G. Peebles Ms.

Georgia Public Health Association Annual Meeting & Conference

Background

The COVID-19 pandemic posed many barriers to healthcare but especially for HIV Public Health clients who struggle to meet basic socioeconomic needs. Southeast Health District (SEHD) Ryan White clients are immunocompromised increasing isolation and fear. In addition to client barriers, the pandemic resulted in a staffing shortage. The shortages were due to COVID diagnosis and subsequent isolation, staffing turnover, and unfillable vacancies.

Method

A dedicated schedule is utilized for Telehealth/Telemedicine. A patient is scheduled at a remote site and connected with a practitioner at another location. The SEHD Ryan White Program currently has 4 clinics located in Bulloch, Coffee, …

Twitter Sentiment Analysis: Applications In Healthcare And Finance, Jiali Wang

Dissertations

This research explores the influence of Twitter sentiment on healthcare and finance industries. It assesses how Twitter sentiment and culture measure influence COVID-19 statistics, and it investigates the impact of Twitter sentiment on S&P 1500 stock mispricing. Furthermore, it examines how tweet sentiment predicts major industry returns.

The first part examines how Hofstede’s Culture Dimensions (HCD) and Twitter economic uncertainty index (TEU) relate to COVID-19 infection rate and death rate. The results show certain aspects in HCD, such as power distance index (PDI) and masculinity (MAS) both are negatively and significantly associated with the infection rate, while indulgence (IVR) and …

Covid-19 Relief For Opportunity Zone Funds And Investors, Adam Wallwork, Gary Hecimovich

Cleveland State Law Review

This Article describes how temporary changes to the qualified opportunity zone (QOZ) tax incentive, combined with new reliance regulations that clarify the requirements for qualified opportunity zone businesses (QOZBs) to modify their written plans to expend working capital in response to the ongoing coronavirus emergency, will make more individuals and entities eligible for federal tax stimulus by increasing flexibility for the qualified opportunity funds (QOFs) and QOZBs in which they invest to redeploy their capital into qualifying business development projects in a QOZ.

Habitat Imaging Biomarkers For Diagnosis And Prognosis In Cancer Patients Infected With Covid-19, Muhammad Aminu, Divya Yadav, Lingzhi Hong, Elliana Young, Paul Edelkamp, Maliazurina Saad, Morteza Salehjahromi, Pingjun Chen, Sheeba J Sujit, Melissa M Chen, Bradley Sabloff, Gregory Gladish, Patricia M De Groot, Myrna C B Godoy, Tina Cascone, Natalie I Vokes, Jianjun Zhang, Kristy K Brock, Naval Daver, Scott E Woodman, Hussein A Tawbi, Ajay Sheshadri, J Jack Lee, David Jaffray, D Code Team, Carol C Wu, Caroline Chung, Jia Wu

Faculty, Staff and Student Publications

OBJECTIVES: Cancer patients have worse outcomes from the COVID-19 infection and greater need for ventilator support and elevated mortality rates than the general population. However, previous artificial intelligence (AI) studies focused on patients without cancer to develop diagnosis and severity prediction models. Little is known about how the AI models perform in cancer patients. In this study, we aim to develop a computational framework for COVID-19 diagnosis and severity prediction particularly in a cancer population and further compare it head-to-head to a general population.

METHODS: We have enrolled multi-center international cohorts with 531 CT scans from 502 general patients and …

Exploring The Benefit Of Introducing Accounting And Finance Knowledge For Micro And Small Entrepreneurs During The Covid-19 Pandemic, Nurul Hidayah, Lucky Nugroho, Harry Suharman, Anees Janee Ali

ASEAN Journal of Community Engagement

This study aims to explore the benefit of introducing the accounting and finance knowledge for micro and small business enterprises, in particular during the time of the coronavirus disease 2019. The COVID-19 pandemic has severely affected the micro and small enterprises. A large number of industries faced the risk of lower sales, which in turn badly hit their businesses. To assist micro and small business entrepreneurs in maintaining sustainability by improving their bookkeeping skills by using digital applications, a team of lecturers from Universitas Mercu Buana, Indonesia, and Universiti Sains Malaysia, Malaysia, collaborated on socialization activities and interactions. The lecturers …

Swallowing Dysfunction Following The Covid-19 Infection: A Literature Reviewarticle, I-Chun Liu, Yi-Hsiang Chiu, Tyng-Guey Wang

Rehabilitation Practice and Science

Coronavirus disease 2019 (COVID-19), named by the World Health Organization in 2020, is a novel infectious disease, causing by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Most symptoms, such as cough and fever, will be resolved following supportive management. However, a small number of patients will progress to respiratory distress or suffer other neurological problems that affect their swallowing function. Potential dysphagia mechanisms associated with COVID-19 include neurological complications, muscular disorder, and intensive care unit-acquired swallowing dysfunctions. As dysphagia results in a declined quality of life and increased risk of respiratory complications, early swallowing interventions are imperative after the acute …

Identifikasi Faktor Stigma Pasien Penyakit Virus Corona (Covid-19) Yang Terkonfirmasi Di Indonesia, Alamsyah Agus, Alfrojems Alfrojems, Jaka Ramdani, Delfania Matasik, Ida Ayu Gde Pradnyawidari Dharmika

Perilaku dan Promosi Kesehatan : Indonesian Journal of Health Promotion and Behavior

Background. The COVID-19 pandemic has emerged as a disaster and is a global health crisis for human beings. The pandemic is not only haunted by tragedies of national fatality rate was about 5% of the sufferers, but also stigmatized by the community. Aim. This study aims to assess the factors of the stigma associated with the COVID-19 pandemic and its impact among patients with confirmed COVID-19 in Indonesia. Method. This case study was conducted in 2020 by collecting information from primary sources that include interviews virtually with 4 COVID-19 survivors in Indonesia. Result. The result of this study shows that …

Racism And Resilience: Counter-Narratives Of Asian International College Students In The Age Of Covid-19, Katrina Liu, Richard Miller, Sharolyn D. Pollard-Durodola, Lei Ping

The Qualitative Report

Using Asian Critical Race Theory and Resilience Theory, this qualitative study explores how Asian international college students experienced racism before and after the eruption of the COVID-19 pandemic and how they developed and used resilience to counteract that racism. Eleven Asian participants shared their counter-narratives through semi-structured interviews. Results reveal that, before the pandemic, participants were regularly subjected to racist acts and attitudes grounded in a deficit view of Asians that treated them as inscrutable foreigners, blamed them as individuals for perceived shortcomings in their home countries, dismissed their expertise outside of technical STEM fields, and failed to recognize their …

Medicine's Roots: Through The Banyan Trees, Emily E. Klosterman

HCA Healthcare Journal of Medicine

I started residency before the COVID-19 pandemic, at a time when we were able to see our patient’s faces without masks, give reassuring smiles, and sit closely while discussing a difficult diagnosis. Little did I know that in 2019, the way we practice would change overnight, as an unprecedented virus took hold. We could no longer see our patients’ faces, reassuring smiles were hidden by masks, and close conversations were held at a distance. Our homes became our claustrophobic havens, and the hospitals were saturated with patients.

Driven by a deep-rooted need to assist others, we continued onward. As life …

Vertical Transmission Of Sars-Cov-2 In A Twin Pregnancy, Tiffany C. Chang, Rebecca F. Herbert, Stacey N. Tran, Victoria M. Weprinsky, Bhaskari Burra, Chi Dola

HCA Healthcare Journal of Medicine

Transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first identified in 2019 and rapidly evolved into the global coronavirus disease 2019 (COVID-19) pandemic. The emergence of a highly morbid disease has posed ongoing challenges in the diagnosis, management, and prevention of COVID-19. The uncertainty underlying medical decision making is further compounded by preexisting conditions, including pregnancy. Here, we report a twin pregnancy complicated by maternal COVID-19 and the vertical transmission of SARS-CoV-2. We hope that our experiences contribute to a better understanding of the disease in pregnancy and, ultimately, guide the development of effective treatment and prevention …

Vitamin D3 Supplementation At 5000 Iu Daily For The Prevention Of Influenza-Like Illness In Healthcare Workers: A Pragmatic Randomized Clinical Trial., Noud Van Helmond, Tracy L Brobyn, Patrick J Lariccia, Teresa Cafaro, Krystal Hunter, Satyajeet Roy, Brigid Bandomer, Kevin Q Ng, Helen Goldstein, Ludmil V Mitrev, Alan Tsai, Denise Thwing, Mary Ann Maag, Myung K Chung

Cooper Medical School of Rowan University Departmental Research

Vitamin D supplementation has been shown to reduce the incidence of acute respiratory infections in populations at risk. The COVID-19 pandemic has highlighted the importance of preventing viral infections in healthcare workers. The aim of this study was to assess the hypothesis that vitamin D3 supplementation at 5000 IU daily reduces influenza-like illness (ILI), including COVID-19, in healthcare workers. We conducted a prospective, controlled trial at a tertiary university hospital. A random group of healthcare workers was invited to receive 5000 IU daily vitamin D3 supplementation for nine months, while other random healthcare system workers served as controls. All healthcare …

An Accurate Real-Time Method For Face Mask Detectionusing Cnn And Svm, Shili Hechmi

Knowledge Engineering and Data Science

Infectious respiratory diseases, including COVID-19, pose a significant challenge to humanity and a potential threat to life due to their severity and rapid spread. Using a surgical mask is among the most significant safety precautions that can help keep this sort of pandemic from spreading, and manual monitoring of large crowds in public places for face masks is problematic. In this research, we suggest a real-time approach for face mask detection. First, we use a multi-scale deep neural network to extract features. As a result, the attributes are better suited for training the detection system. We employ SVM post-processing in …

Social Media Mining With Fuzzy Text Matching: A Knowledge Extraction On Tourism After Covid-19 Pandemic, Ida Bagus Putra Manuaba, I Wayan Budi Sentana, I Nyoman Gede Arya Astawa, I Wayan Suasnawa, I Putu Bagus Arya Pradnyana

Knowledge Engineering and Data Science

Social media mining is an emerging technique for analyzing data to extract valuable knowledge related to various domains. However, traditional text matching techniques, such as exact matching, are not always suitable for social media data, which can contain spelling mistakes, abbreviations, and variations in the use of words. Fuzzy matching is a text matching technique that can handle such variations and identify similarities between two texts, even if there are differences in spelling or phrasing. The gap in existing research is the limited use of fuzzy matching in social media mining for tourism recovery analysis. By applying fuzzy matching to …

Analisis Kematian Covid-19 Dengan Standardisasi Usia Berdasarkan Wilayah Di Indonesia Periode Maret 2020 – Mei 2021, Adistikah Aqmarina

Jurnal Epidemiologi Kesehatan Indonesia

COVID-19 merupakan jenis penyakit menular baru yang sampai saat ini masih ditetapkan sebagai pandemi. Berbagai studi menyebutkan risiko kematian COVID-19 lebih tinggi pada kelompok lanjut usia terutama dengan riwayat penyakit penyerta. Ketersediaan rumah sakit dan laboratorium pemeriksa COVID- 19 yang tidak adekuat juga dapat memberikan pengaruh terhadap tingginya angka kematian COVID-19. Studi ini bertujuan untuk membandingkan tingkat kematian COVID-19 di wilayah Indonesia dengan mengontrol variabel usia serta didukung dengan analisis ketersediaan rumah sakit dan laboratorium pemeriksa COVID-19. Penelitian ini menggunakan desain studi potong lintang (cross sectional) dengan data sekunder laporan COVID-19 nasional di Kementerian Kesehatan periode Maret 2020 – Mei …

Faktor - Faktor Yang Berhubungan Dengan Kematian Pasien Covid-19 Lansia Di Ruang Rawat Inap Rsud Kabupaten Karanganyar, Soraya Hidayati, Nurhayati Adnan Prihartono

Jurnal Epidemiologi Kesehatan Indonesia

Virus COVID-19 terus menyebabkan lebih banyak orang menjadi sakit dan meninggal dunia setiap harinya. Selain itu, varian virus COVID-19 baru juga terus ditemukan. Lebih dari 80% kematian karena COVID-19 terjadi pada penderita yang memiliki komorbid dan berusia di atas 65 tahun. Perlu diketahui penyakit komorbid apa saja yang berpengaruh terhadap kematian pasien COVID- 19 lansia. Tujuan penelitian ini adalah untuk mengetahui faktorfaktor yang dapat meningkatkan risiko kematian COVID-19 pada pasien lansia yang melakukan rawat inap di RSUD Karanganyar mulai Januari 2020 - Mei 2021. Sebanyak 322 pasien COVID-19 lansia yang terdata dalam file database rekam medis pasien rawat inap di …

Biaya Pengobatan Pasien Rawat Inap Covid-19 Di Rumah Sakit X Tahun 2021, Reli Giusman, Atik Nurwahyuni

Jurnal Ekonomi Kesehatan Indonesia

The COVID-19 pandemic has caused various hospitals in the world to experience difficulties in providing services because the number of patients has soared in a short time. The widespread pandemic with high mortality in various parts of the country has resulted in high hospitalizations for patients due to COVID-19, so the cost of treatment has also increased. The purpose of this study was to analyze the cost of treating COVID-19 inpatients at Hospital X. The data used is secondary data derived from INACBG's data and medical records as many as 1,196 samples in the period August 2020 to April 2021. …

Kajian Atas Risiko Kelompok Usia Dan Klaim Rumah Sakit (Rs) Covid-19 Di Indonesia, 2020 – 2021, Andhika Nurwin Maulana, Ruli E Al Faizin, Kalsum Komaryani, Farah Purwaningrum, Hasbullah Thabrany

Jurnal Ekonomi Kesehatan Indonesia

This study measures the risk of age group and its correlation with severity level, length-of-stay (LOS), cost of treatment, and discharge of inpatient status. By ‘age group’ we refer to children, productive, and elderly. Since mid-2020 government of Indonesia opted for a micro lockdown in several areas to reduce pandemic transmission nevertheless ensure economic recovery. However, people will have a higher risk if they conduct economic activities, moreover if they were to take public transport to their workplace. We also measure several differences between the implementation of technical guidance of 4th and 5th had a more significant differences in LOS …

Vocabulary Masks, Kim Hardiman

Journal of English Learner Education

As language instructors, we should teach vocabulary in every lesson. How can we combine L2 vocabulary with active teaching and learning techniques? In the past, language instructors taught EL to write long word lists int their notebooks. Do ELs remember these new words? Is there a better way to teach vocabulary for ELs to practice using them in authentic context? Wearing masks has become a daily activity around the world. ELs can express and share their raw emotions by writing and wearing inspirational words on their masks. Vocabulary masks will ignite salient discussions and reconnect ELs with their emotional journeys …

Putting The Coronavirus To Work: Developing A Global Engineering Program During A Pandemic, Cynthia S. Chalupa

Journal of International Engineering Education

In the aftermath of COVID-19 shutdowns at campuses across the U.S. in the spring of 2020, student enrollments have fallen and budgets have been severely constrained. To counteract the current and long-term repercussions of the pandemic on institutions of higher education, administrators have called for innovative program development and strategic transformation. In the past, many engineering and world languages departments may have considered the task of creating a collaborative degree program insurmountable or undesirable despite existing models that are successful (e.g. University of Rhode Island’s IEP program). In the era of COVID-19, however, innovative programs combining language with disciplines outside …

2022-12-28_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

2022-12-27_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/stats/data-about-places/long-term-care-data.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data for all reporting facilities is posted weekly each Monday.

The information below represents COVID-19 data reported directly to MDHHS by licensed and operating Skilled Nursing, Home for the Aged and Adult Foster Care facilities (licensed to serve 13 or more individuals) in Michigan from January 1, 2020. All long-term care facilities additionally have an obligation to report COVID-positive residents and/or staff …

2022-12-27_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus/stats.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. COVID case and testing data will be posted once a week on Tuesdays.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) …