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Athletic Identity And Psychological Distress: The Moderating Roles Of Social Support And Self-Compassion, Carmyn J. Hayes, Trent A. Petrie, Whitney G. Moore Feb 2024

Athletic Identity And Psychological Distress: The Moderating Roles Of Social Support And Self-Compassion, Carmyn J. Hayes, Trent A. Petrie, Whitney G. Moore

Journal of Issues in Intercollegiate Athletics

No abstract provided.


Pre-Infection Innate Immunity Attenuates Sars-Cov-2 Infection And Viral Load In Ipsc-Derived Alveolar Epithelial Type 2 Cells, Satish Kumar, Jose C. Granados, Miriam Aceves, Juan M. Peralta, Ana C. Leandro, John M. Thomas, Sarah Williams-Blangero, Joanne E. Curran, John Blangero Feb 2024

Pre-Infection Innate Immunity Attenuates Sars-Cov-2 Infection And Viral Load In Ipsc-Derived Alveolar Epithelial Type 2 Cells, Satish Kumar, Jose C. Granados, Miriam Aceves, Juan M. Peralta, Ana C. Leandro, John M. Thomas, Sarah Williams-Blangero, Joanne E. Curran, John Blangero

School of Medicine Publications

A large portion of the heterogeneity in coronavirus disease 2019 (COVID-19) susceptibility and severity of illness (SOI) remains poorly understood. Recent evidence suggests that SARS-CoV-2 infection-associated damage to alveolar epithelial type 2 cells (AT2s) in the distal lung may directly contribute to disease severity and poor prognosis in COVID-19 patients. Our in vitro modeling of SARS-CoV-2 infection in induced pluripotent stem cell (iPSC)-derived AT2s from 10 different individuals showed interindividual variability in infection susceptibility and the postinfection cellular viral load. To understand the underlying mechanism of the AT2′s capacity to regulate SARS-CoV-2 infection and cellular viral load, a genome-wide differential …


Post Covid-19 Recovery In Mountain West Metros, Zachary Walusek, Vanessa Booth, Annie Vong, Caitlin J. Saladino, William E. Brown Jr. Feb 2024

Post Covid-19 Recovery In Mountain West Metros, Zachary Walusek, Vanessa Booth, Annie Vong, Caitlin J. Saladino, William E. Brown Jr.

Economic Development & Workforce

This fact sheet examines data on the economic effects of the COVID-19 pandemic and recession on Mountain West metros. The original report includes data on economic activity, labor market, and real estate trends.


New Onset Positive Autoantibodies Following Covid-19 Infection, David Hernandez, Adnaan Sheikh, Shakira Laing, Mariana Adieb, Omar Siddiqui, Rohail Baig, Annabel Antonini, James Vienneau, Camden Burns Feb 2024

New Onset Positive Autoantibodies Following Covid-19 Infection, David Hernandez, Adnaan Sheikh, Shakira Laing, Mariana Adieb, Omar Siddiqui, Rohail Baig, Annabel Antonini, James Vienneau, Camden Burns

Advances in Clinical Medical Research and Healthcare Delivery

The World Health Organization (WHO) declared the novel coronavirus (COVID-19) outbreak a global pandemic on March 11, 2020. Since the original outbreak in December 2019, over 100 million people have been confirmed to have been infected by COVID-19 and over two million people have died. The presentation seen in patients may vary widely based on multiple factors. Fever has been reported in up to 99% of patients, while other common symptoms seen are dyspnea, fatigue, anosmia, and myalgia. Around 80% of COVID-19 patients present with a mild respiratory illness that can be managed at home, while around 15% need basic …


Covid-19-Associated Myocarditis: Screening For Early Diagnosis, Yousuf Khan, Salmman Ahmed, Samuel John Wlasowicz, Ronald G. Lott Iii, Xavier C. Zonna Feb 2024

Covid-19-Associated Myocarditis: Screening For Early Diagnosis, Yousuf Khan, Salmman Ahmed, Samuel John Wlasowicz, Ronald G. Lott Iii, Xavier C. Zonna

Advances in Clinical Medical Research and Healthcare Delivery

The SARS-CoV-2 virus (causing COVID-19), has infected about 770 million people, and caused the death of about 6.9 million people worldwide in the span of three years (John Hopkins Resource Center). Common symptoms of a patient infected with the virus include shortness of breath, fever, chills, fatigue, loss of taste or smell, and muscle aches. However, recent studies have also shown a prevalence of patients presenting with cardiac inflammation (endocarditis, myocarditis or pericarditis) as a potential comorbidity, both during the infectious stage as well as after the infection has subsided. A pattern of specific clinical markers may be indicative of …


Covid-19 Risk Factors And Boilerplate Disclosure, Stephen J. Choi, Mitu Gulati, Xuan Liu, Adam C. Pritchard Feb 2024

Covid-19 Risk Factors And Boilerplate Disclosure, Stephen J. Choi, Mitu Gulati, Xuan Liu, Adam C. Pritchard

Law & Economics Working Papers

The SEC mandates that public companies assess new information that changes the risks that they face and disclose these if there has been a “material” change. Does that theory work in practice? Or are companies copying and repeating the same generic disclosures? Using the shock of the COVID-19 pandemic, we explore these questions. Overall, we find considerable rote copying of boilerplate disclosures. Further, the factors that correlate with deviations from the boilerplate seem related more to the resources that companies have (large companies change updated disclosures more) and litigation risks (companies vulnerable to shareholder litigation update more) rather than general …


Race-Related Stress, Medical Mistrust, Covid-19 Worry, And Covid-19 Vaccination Behavior Among African Americans, Lisa A. Cash Feb 2024

Race-Related Stress, Medical Mistrust, Covid-19 Worry, And Covid-19 Vaccination Behavior Among African Americans, Lisa A. Cash

Walden Dissertations and Doctoral Studies

In the United States, nearly 104 million cases and over 1.1 million deaths from novel coronavirus disease of 2019 (COVID-19) have been reported overall, but African Americans have been disproportionately affected. Nevertheless, this population has demonstrated the lowest intention to be vaccinated and lowest vaccination rates of all racial/ethnic groups in the United States. The research problem addressed by this study is African American COVID-19 health disparities. The purpose of this investigation was to examine factors that influence COVID-19 vaccination behavior among African Americans, which is important to better understand how to achieve health equity. Using the health belief model …


Recombinant Rod Domain Of Vimentin Reduces Sars-Cov-2 Viral Replication By Blocking Spike Protein-Ace2 Interactions, Fong Wilson Lam, Cameron August Brown, Shannon Elizabeth Ronca Feb 2024

Recombinant Rod Domain Of Vimentin Reduces Sars-Cov-2 Viral Replication By Blocking Spike Protein-Ace2 Interactions, Fong Wilson Lam, Cameron August Brown, Shannon Elizabeth Ronca

Faculty, Staff and Students Publications

Although the SARS-CoV-2 vaccination is the primary preventive intervention, there are still few antiviral therapies available, with current drugs decreasing viral replication once the virus is intracellular. Adding novel drugs to target additional points in the viral life cycle is paramount in preventing future pandemics. The purpose of this study was to create and test a novel protein to decrease SARS-CoV-2 replication. We created the recombinant rod domain of vimentin (rhRod) in E. coli and used biolayer interferometry to measure its affinity to the SARS-CoV-2 S1S2 spike protein and the ability to block the SARS-CoV-2–ACE2 interaction. We performed plaque assays …


Factors Influencing Music Therapists’ Retention Of Clinical Hours With Autistic Clients Over Telehealth During The Covid-19 Pandemic, Nicole M. Richard Williams Feb 2024

Factors Influencing Music Therapists’ Retention Of Clinical Hours With Autistic Clients Over Telehealth During The Covid-19 Pandemic, Nicole M. Richard Williams

Faculty Scholarship

The COVID-19 pandemic influenced music therapists to migrate services to online platforms, though some lost clinical hours during the pandemic when telehealth was not a viable option. This survey study aimed to ascertain factors that helped music-based therapists to continue serving autistic clients over telehealth during the pandemic. We surveyed 193 accredited music therapists located mainly in Canada and the United States. In addition to gathering data on general perceptions of telehealth music therapy and Neurologic Music Therapy® (NMT), one-way ANOVAs were applied to determine differences in percent-change loss of clinical hours for music therapists: 1) working in different employment …


Description Of Cryptococcosis Following Sars-Cov-2 Infection: A Disease Survey Through The Mycosis Study Group Education And Research Consortium (Msg-19), Jeremey Walker, Todd Mccarty, Gerald Mcgwin, Eloy E Ordaya, Paschalis Vergidis, Luis Ostrosky-Zeichner, Mehriban Mammadova, Andrej Spec, Adriana M Rauseo, John Perfect, Julia Messina, Gabriel Vilchez, Rachel Mcmullen, Carolynn T Jones, Peter G Pappas Feb 2024

Description Of Cryptococcosis Following Sars-Cov-2 Infection: A Disease Survey Through The Mycosis Study Group Education And Research Consortium (Msg-19), Jeremey Walker, Todd Mccarty, Gerald Mcgwin, Eloy E Ordaya, Paschalis Vergidis, Luis Ostrosky-Zeichner, Mehriban Mammadova, Andrej Spec, Adriana M Rauseo, John Perfect, Julia Messina, Gabriel Vilchez, Rachel Mcmullen, Carolynn T Jones, Peter G Pappas

Faculty, Staff and Student Publications

BACKGROUND: Invasive fungal infections have been described throughout the COVID-19 pandemic. Cryptococcal disease after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been reported in several isolated case reports and 1 larger case series. We sought to describe cryptococcal infections following SARS-CoV-2 through establishing a database to investigate underlying risk factors, disease manifestations, and outcomes.

METHODS: We created a crowdsourced call for cases solicited through the Mycoses Study Group Education and Research Consortium, the Centers for Disease Control and Prevention Emerging Infectious Diseases Network, and infectious diseases Twitter groups. Data were collected in a web-based and secure REDCap …


Description Of Cryptococcosis Following Sars-Cov-2 Infection: A Disease Survey Through The Mycosis Study Group Education And Research Consortium (Msg-19), Jeremey Walker, Andrej Spec, Adriana M Rauseo, Et Al. Feb 2024

Description Of Cryptococcosis Following Sars-Cov-2 Infection: A Disease Survey Through The Mycosis Study Group Education And Research Consortium (Msg-19), Jeremey Walker, Andrej Spec, Adriana M Rauseo, Et Al.

2020-Current year OA Pubs

BACKGROUND: Invasive fungal infections have been described throughout the COVID-19 pandemic. Cryptococcal disease after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been reported in several isolated case reports and 1 larger case series. We sought to describe cryptococcal infections following SARS-CoV-2 through establishing a database to investigate underlying risk factors, disease manifestations, and outcomes.

METHODS: We created a crowdsourced call for cases solicited through the Mycoses Study Group Education and Research Consortium, the Centers for Disease Control and Prevention Emerging Infectious Diseases Network, and infectious diseases Twitter groups. Data were collected in a web-based and secure REDCap …


Backfilling Patients In Phase I Dose-Escalation Trials Using Bayesian Optimal Interval Design (Boin), Yixuan Zhao, Ying Yuan, Edward L Korn, Boris Freidlin Feb 2024

Backfilling Patients In Phase I Dose-Escalation Trials Using Bayesian Optimal Interval Design (Boin), Yixuan Zhao, Ying Yuan, Edward L Korn, Boris Freidlin

Faculty, Staff and Student Publications

In recent years, there has been increased interest in incorporation of backfilling into dose-escalation clinical trials, which involves concurrently assigning patients to doses that have been previously cleared for safety by the dose-escalation design. Backfilling generates additional information on safety, tolerability, and preliminary activity on a range of doses below the maximum tolerated dose (MTD), which is relevant for selection of the recommended phase II dose and dose optimization. However, in practice, backfilling may not be rigorously defined in trial protocols and implemented consistently. Furthermore, backfilling designs require careful planning to minimize the probability of treating additional patients with potentially …


Acute Neutrophilic Vasculitis (Leukocytoclasia) In 36 Covid-19 Autopsy Brains, Roy H. Rhodes, Gordon L. Love, Fernanda Da Silva Lameira, Maryam Sadough Shahmirzadi, Sharon E. Fox, Richard S. Vander Heide Feb 2024

Acute Neutrophilic Vasculitis (Leukocytoclasia) In 36 Covid-19 Autopsy Brains, Roy H. Rhodes, Gordon L. Love, Fernanda Da Silva Lameira, Maryam Sadough Shahmirzadi, Sharon E. Fox, Richard S. Vander Heide

School of Medicine Faculty Publications

Background: Hypercytokinemia, the renin-angiotensin system, hypoxia, immune dysregulation, and vasculopathy with evidence of immune-related damage are implicated in brain morbidity in COVID-19 along with a wide variety of genomic and environmental influences. There is relatively little evidence of direct SARS-CoV-2 brain infection in COVID-19 patients. Methods: Brain histopathology of 36 consecutive autopsies of patients who were RT-PCR positive for SARS-CoV-2 was studied along with findings from contemporary and pre-pandemic historical control groups. Immunostaining for serum and blood cell proteins and for complement components was employed. Microcirculatory wall complement deposition in the COVID-19 cohort was compared to historical control cases. Comparisons …


Diabetes And Covid-19 Outcomes: An Analysis Of Freeman Health System Patients, Timothy Wiant, Logan Schmidt, Saibhavana Srikakolapu, Nova Beyersdorfer, Mariam Akhtar, Kerry Johnson, Greg Stahl, Darrin S. Goade, Robert Arnce Feb 2024

Diabetes And Covid-19 Outcomes: An Analysis Of Freeman Health System Patients, Timothy Wiant, Logan Schmidt, Saibhavana Srikakolapu, Nova Beyersdorfer, Mariam Akhtar, Kerry Johnson, Greg Stahl, Darrin S. Goade, Robert Arnce

Faculty and Staff Publications

Background: As COVID-19 continues to affect millions of people around the world, it has become vital to understand how comorbidities such as diabetes affect the health outcomes of these patients. While earlier studies have focused on major metropolitan areas, rural settings have been comparatively understudied. The goal of this study is to understand the effect on mortality that these two diseases have in the inpatient setting of a rural population.

Methods: The electronic medical records of all adult patients admitted to Freeman Health System, Joplin, Missouri, United States, between April 1, 2020, and December 31, 2021, were reviewed for the …


Sars-Cov-2 Versus Other Duty-Related Deaths Among United States Law Enforcement Officers, Jessica Lizeth Alvitres Feb 2024

Sars-Cov-2 Versus Other Duty-Related Deaths Among United States Law Enforcement Officers, Jessica Lizeth Alvitres

Walden Dissertations and Doctoral Studies

In 2020, more than half of United States law enforcement officer deaths were attributed to COVID-19, spurring the need for further investigation into the impact of the SARS-CoV-2 pandemic on this category of frontline essential workers. The purpose of this quantitative secondary data analysis study was to investigate the existence of associations between U.S. law enforcement officer deaths (SARS-CoV-2, non-SARS-CoV-2, or other duty-related) and the geographic region, as well as year of death while controlling for the officer rank, age, and sex. Based on the conceptual framework for evaluating mortality and morbidity following large-scale disasters from the National Academies of …


Economic Impacts Of The Covid-19 Pandemic On Families Of Children With Autism And Other Developmental Disabilities., Olivia M. Pokoski, Hayley Crain, Carolyn Diguiseppi, Sarah M. Furnier, Eric J. Moody, Cy Nadler, Karen Pazol, Jessica Sanders, Lisa D. Wiggins, Maureen S. Durkin Feb 2024

Economic Impacts Of The Covid-19 Pandemic On Families Of Children With Autism And Other Developmental Disabilities., Olivia M. Pokoski, Hayley Crain, Carolyn Diguiseppi, Sarah M. Furnier, Eric J. Moody, Cy Nadler, Karen Pazol, Jessica Sanders, Lisa D. Wiggins, Maureen S. Durkin

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: To control the spread of the coronavirus disease (COVID-19), many jurisdictions throughout the world enacted public health measures that had vast socio-economic implications. In emergency situations, families of children with developmental disabilities (DDs), including autism, may experience increased difficulty accessing therapies, economic hardship, and caregiver stress, with the potential to exacerbate autism symptoms. Yet, limited research exists on the economic impacts of the COVID-19 pandemic on families of children with autism or another DD compared to families of children from the general population.

OBJECTIVES: To assess impact of the COVID-19 pandemic related to parental employment and economic difficulties in …


Authors’ Response To Peer Reviews Of “Covid-19 National Football League (Nfl) Injury Analysis: Follow-Up Study”, Troy B. Puga, Joshua Schafer, Grace Thiel, Nicholas Scigliano, Tiffany Ruan, Andres Toledo, Prince N. Agbedanu, Kevin Treffer Feb 2024

Authors’ Response To Peer Reviews Of “Covid-19 National Football League (Nfl) Injury Analysis: Follow-Up Study”, Troy B. Puga, Joshua Schafer, Grace Thiel, Nicholas Scigliano, Tiffany Ruan, Andres Toledo, Prince N. Agbedanu, Kevin Treffer

Student Publications

No abstract provided.


Design, Synthesis, X-Ray Crystallography, And Biological Activities Of Covalent, Non-Peptidic Inhibitors Of Sars-Cov-2 Main Protease, Md Ashraf-Uz-Zaman, Teck Khiang Chua, Xin Li, Yuan Yao, Bala Krishna Moku, Chandra Bhushan Mishra, Vasanthi Avadhanula, Pedro A Piedra, Yongcheng Song Feb 2024

Design, Synthesis, X-Ray Crystallography, And Biological Activities Of Covalent, Non-Peptidic Inhibitors Of Sars-Cov-2 Main Protease, Md Ashraf-Uz-Zaman, Teck Khiang Chua, Xin Li, Yuan Yao, Bala Krishna Moku, Chandra Bhushan Mishra, Vasanthi Avadhanula, Pedro A Piedra, Yongcheng Song

Faculty, Staff and Students Publications

Highly contagious SARS-CoV-2 coronavirus has infected billions of people worldwide with flu-like symptoms since its emergence in 2019. It has caused deaths of several million people. The viral main protease (Mpro) is essential for SARS-CoV-2 replication and therefore a drug target. Several series of covalent inhibitors of Mpro were designed and synthesized. Structure-activity relationship studies show that 1) several chloroacetamide- and epoxide-based compounds targeting Cys145 are potent inhibitors with IC50 values as low as 0.49 μM, and 2) Cys44 of Mpro is not nucleophilic for covalent inhibitor design. High resolution X-ray studies revealed the protein-inhibitor interactions and mechanisms of inhibition. …


Immunoglobulin Replacement Products Protect Against Sars-Cov-2 Infection In Vivo Despite Poor Neutralizing Activity, Ofer Zimmerman, Alexa Michelle Altman Doss, Baoling Ying, Chieh-Yu Liang, Samantha R. Mackin, Hannah G. Davis-Adams, Lucas J. Adams, Laura A. Vanblargan, Rita E. Chen, Suzanne M. Scheaffer, Pritesh Desai, Saravanan Raju, Tarisa L. Mantia, Caitlin C. O'Shaughnessy, Jennifer Marie Monroy, H. James Wedner, Christopher J. Rigell, Andrew L. Kau, Tiffany Biason Dy, Zhen Ren, Jackson S. Turner, Jane A. O'Halloran, Rachel M. Presti, Peggy L. Kendall, Daved H. Fremont, Ali H. Ellebedy, Michael S Diamond Feb 2024

Immunoglobulin Replacement Products Protect Against Sars-Cov-2 Infection In Vivo Despite Poor Neutralizing Activity, Ofer Zimmerman, Alexa Michelle Altman Doss, Baoling Ying, Chieh-Yu Liang, Samantha R. Mackin, Hannah G. Davis-Adams, Lucas J. Adams, Laura A. Vanblargan, Rita E. Chen, Suzanne M. Scheaffer, Pritesh Desai, Saravanan Raju, Tarisa L. Mantia, Caitlin C. O'Shaughnessy, Jennifer Marie Monroy, H. James Wedner, Christopher J. Rigell, Andrew L. Kau, Tiffany Biason Dy, Zhen Ren, Jackson S. Turner, Jane A. O'Halloran, Rachel M. Presti, Peggy L. Kendall, Daved H. Fremont, Ali H. Ellebedy, Michael S Diamond

2020-Current year OA Pubs

Immunoglobulin (IG) replacement products are used routinely in patients with immune deficiency and other immune dysregulation disorders who have poor responses to vaccination and require passive immunity conferred by commercial antibody products. The binding, neutralizing, and protective activity of intravenously administered IG against SARS-CoV-2 emerging variants remains unknown. Here, we tested 198 different IG products manufactured from December 2019 to August 2022. We show that prepandemic IG had no appreciable cross-reactivity or neutralizing activity against SARS-CoV-2. Anti-spike antibody titers and neutralizing activity against SARS-CoV-2 WA1/2020 D614G increased gradually after the pandemic started and reached levels comparable to vaccinated healthy donors …


How Does Covid-19 Vaccination Affect Long-Covid Symptoms?, Ali Akbar Asadi-Pooya, Meshkat Nemati, Mina Shahisavandi, Hamid Nemati, Afrooz Karimi, Anahita Jafari, Sara Nasiri, Seyyed Saeed Mohammadi, Zahra Rahimian, Hossein Bayat, Ali Akbari, Amir Emami, Owrang Eilami Feb 2024

How Does Covid-19 Vaccination Affect Long-Covid Symptoms?, Ali Akbar Asadi-Pooya, Meshkat Nemati, Mina Shahisavandi, Hamid Nemati, Afrooz Karimi, Anahita Jafari, Sara Nasiri, Seyyed Saeed Mohammadi, Zahra Rahimian, Hossein Bayat, Ali Akbari, Amir Emami, Owrang Eilami

Department of Neurology Faculty Papers

OBJECTIVE: The current study aimed to identify the association between COVID-19 vaccination and prolonged post-COVID symptoms (long-COVID) in adults who reported suffering from this condition.

METHODS: This was a retrospective follow-up study of adults with long-COVID syndrome. The data were collected during a phone call to the participants in January-February 2022. We inquired about their current health status and also their vaccination status if they agreed to participate.

RESULTS: In total, 1236 people were studied; 543 individuals reported suffering from long long- COVID (43.9%). Chi square test showed that 15 out of 51 people (29.4%) with no vaccination and 528 …


A Phenomenological Study On The Contributors Of Compassion Fatigue With Substance Use Disorder Counselors During The Covid-19 Pandemic, Jennifer A. Galvano Feb 2024

A Phenomenological Study On The Contributors Of Compassion Fatigue With Substance Use Disorder Counselors During The Covid-19 Pandemic, Jennifer A. Galvano

Doctoral Dissertations and Projects

This phenomenological study aimed to understand the experience of compassion fatigue in substance use counselors in Western New York during the COVID-19 pandemic. Many studies have reviewed burnout, compassion fatigue, and secondary trauma and have discussed the outcomes of their unmanaged effects on healthcare professionals. Few have focused directly on the impact that key contributors of compassion fatigue have on substance abuse disorder (SUD) counselors. This qualitative study is designed to support substance abuse counselors’ mental health and well-being. Counselors are exposed to clashing situations such as turnover, larger caseloads, client trauma, regulations, lack of training, lack of understanding of …


A Phenomenological Multi-Case Study Of Perceptions Of Older Adults’ Loneliness During Covid-19 Within Selected Online Churches, Bethney Wright Sikes Feb 2024

A Phenomenological Multi-Case Study Of Perceptions Of Older Adults’ Loneliness During Covid-19 Within Selected Online Churches, Bethney Wright Sikes

Doctoral Dissertations and Projects

The purpose of this phenomenological multi-case study was to understand the perceptions of older adults regarding their feelings of loneliness related to the lockdown during COVID-19 and to discover if online church platforms for the older adult Christian population at Crosspoint Church in Niceville, Florida, Cross Church in Northwest Arkansas, and Community Life Church in Gulf Breeze, Florida, minimized those feelings of loneliness which may have caused mental, physical, and emotional concerns. Isolation from the church body was generally defined as nonattendance via traditional means or online platforms. The theory guiding this study was Lev Vygotsky’s zone of proximal development. …


Building Community For Those Living With Hiv: Co-Empowerment And Participatory Action Research, Patricia M. Miller Dr., Brent Oliver Dr., Ken Lapointe, Kim A. Samson, Vincenzo Sabella Mr. Feb 2024

Building Community For Those Living With Hiv: Co-Empowerment And Participatory Action Research, Patricia M. Miller Dr., Brent Oliver Dr., Ken Lapointe, Kim A. Samson, Vincenzo Sabella Mr.

The Qualitative Report

The Calgary HIV Social Society (CHSS) self-determined and organized several social-recreational monthly events to reduce and understand the effects of social isolation and stigma that people living with HIV face every day. It has been found that COVID-19 had impacted the lives of people living with HIV by creating significant isolation for those already stigmatized because of living with HIV. Using a Participatory Action Research (PAR) methodology and focus group at the end of the events, the research showed how COVID 19, and the related concurring isolation has impacted the lives of people living with HIV. The research included three …


Covid‐19 Infection Is Associated With Poor Outcomes In Patients With Intracerebral Hemorrhage, Daniela Renedo, Audrey C. Leasure, Rebecca Young, Cyprien A. Rivier, Brooke Alhanti, Brian Mac Grory, Steven R. Messe, Mathew J. Reeves, Ameer E. Hassan, Lee Schwamm Feb 2024

Covid‐19 Infection Is Associated With Poor Outcomes In Patients With Intracerebral Hemorrhage, Daniela Renedo, Audrey C. Leasure, Rebecca Young, Cyprien A. Rivier, Brooke Alhanti, Brian Mac Grory, Steven R. Messe, Mathew J. Reeves, Ameer E. Hassan, Lee Schwamm

School of Medicine Publications

Background

Patients with ischemic stroke and concomitant COVID‐19 infection have worse outcomes than those without this infection, but the impact of COVID‐19 on hemorrhagic stroke remains unclear. We aimed to assess if COVID‐19 worsens outcomes in intracerebral hemorrhage (ICH).

Methods and Results

We conducted an observational study of ICH outcomes using Get With The Guidelines Stroke data. We compared patients with ICH who were COVID‐19 positive and negative during the pandemic (March 2020–February 2021) and prepandemic (March 2019–February 2020). Main outcomes were poor functional outcome (defined as a modified Rankin scale score of 4 to 6 at discharge), mortality, and …


Covid-19 Hospital Mortality Among Patients With Invasive Mechanical Ventilation: A Comparison Between Public And Private Healthcare Services In San Luis Potosí 2020–2022, María E. Torres-Acosta, Rocío M. Cubos-Moncada, Alan Y. Martínez-Castellanos Feb 2024

Covid-19 Hospital Mortality Among Patients With Invasive Mechanical Ventilation: A Comparison Between Public And Private Healthcare Services In San Luis Potosí 2020–2022, María E. Torres-Acosta, Rocío M. Cubos-Moncada, Alan Y. Martínez-Castellanos

The University of Louisville Journal of Respiratory Infections

Background: During 2019, México’s total public spending on health was 5.43% of the national gross domestic product, making it one of the countries of the Organisation for Economic Co-operation and Development that invested the least in developing public health systems. This study analyzes hospital mortality among intubated patients with laboratory-confirmed COVID-19 according to type of institution in San Luis Potosí, México, from March 18, 2020, to April 7, 2022.

Methods: This is a secondary data analysis of publicly available information about mortality among intubated patients with a laboratory-confirmed diagnosis of COVID-19 with respect to the type of hospitalization institution.

Results: …


Developing Public Health Surveillance Dashboards: A Scoping Review On The Design Principles, Reza Rabiei, Peivand Bastani, Hossein Ahmadi, Shirin Dehghan, Sohrab Almasi Feb 2024

Developing Public Health Surveillance Dashboards: A Scoping Review On The Design Principles, Reza Rabiei, Peivand Bastani, Hossein Ahmadi, Shirin Dehghan, Sohrab Almasi

School of Nursing and Midwifery

Background: Public Health Dashboards (PHDs) facilitate the monitoring and prediction of disease outbreaks by continuously monitoring the health status of the community. This study aimed to identify design principles and determinants for developing public health surveillance dashboards. Methodology: This scoping review is based on Arksey and O'Malley's framework as included in JBI guidance. Four databases were used to review and present the proposed principles of designing PHDs: IEEE, PubMed, Web of Science, and Scopus. We considered articles published between January 1, 2010 and November 30, 2022. The final search of articles was done on November 30, 2022. Only articles in …


Health Economic Consequences Associated With Covid-19-Related Delay In Melanoma Diagnosis In Europe, Lara V Maul, Dagmar Jamiolkowski, Rebecca A Lapides, Alina M Mueller, Axel Hauschild, Claus Garbe, Paul Lorigan, Jeffrey E Gershenwald, Paolo Antonio Ascierto, Georgina V Long, Michael Wang-Evers, Richard A Scolyer, Babak Saravi, Matthias Augustin, Alexander A Navarini, Stefan Legge, István B Németh, Ágnes J Jánosi, Simone Mocellin, Anita Feller, Dieter Manstein, Alexander Zink, Julia-Tatjana Maul, Alessandra Buja, Kaustubh Adhikari, Elisabeth Roider Feb 2024

Health Economic Consequences Associated With Covid-19-Related Delay In Melanoma Diagnosis In Europe, Lara V Maul, Dagmar Jamiolkowski, Rebecca A Lapides, Alina M Mueller, Axel Hauschild, Claus Garbe, Paul Lorigan, Jeffrey E Gershenwald, Paolo Antonio Ascierto, Georgina V Long, Michael Wang-Evers, Richard A Scolyer, Babak Saravi, Matthias Augustin, Alexander A Navarini, Stefan Legge, István B Németh, Ágnes J Jánosi, Simone Mocellin, Anita Feller, Dieter Manstein, Alexander Zink, Julia-Tatjana Maul, Alessandra Buja, Kaustubh Adhikari, Elisabeth Roider

Faculty, Staff and Student Publications

IMPORTANCE: The COVID-19 pandemic resulted in delayed access to medical care. Restrictions to health care specialists, staff shortages, and fear of SARS-CoV-2 infection led to interruptions in routine care, such as early melanoma detection; however, premature mortality and economic burden associated with this postponement have not been studied yet.

OBJECTIVE: To determine the premature mortality and economic costs associated with suspended melanoma screenings during COVID-19 pandemic lockdowns by estimating the total burden of delayed melanoma diagnoses for Europe.

DESIGN, SETTING, AND PARTICIPANTS: This multicenter economic evaluation used population-based data from patients aged at least 18 years with invasive primary cutaneous …


A Proposed Method For Quality Evaluation Of Covid-19 Reusable Face Mask, Mehrbakhsh Nilashi, Rabab Ali Abumalloh, Hossein Ahmadi, Mesfer Alrizq, Abdullah Alghamdi, Omar A. Alghamdi, Sultan Alyami Feb 2024

A Proposed Method For Quality Evaluation Of Covid-19 Reusable Face Mask, Mehrbakhsh Nilashi, Rabab Ali Abumalloh, Hossein Ahmadi, Mesfer Alrizq, Abdullah Alghamdi, Omar A. Alghamdi, Sultan Alyami

School of Nursing and Midwifery

During the time of COVID-19, the use of face masks has become an essential control and prevention measure. The wide usage of disposable face masks has presented a great challenge to governments to face the impact of plastic waste on humans health and the environment. The quality of reusable face masks was assessed in previous research based on general measures such as the fabric, size fit, arrival time, price, and convenience, and based on more-specific measures related to the number of layers and the included filters. However, as the quality of reusable face masks includes several other dimensions, the general …


Immune Response To Sars-Cov-2 Variants After Immunization With Different Vaccines In Mexico, Erika Garay, Sean P J Whelan, Rebecca M Dubois, Sara M O'Rourke, Angel Eduardo Salgado-Escobar, José Esteban Muñoz-Medina, Carlos F Arias, Susana López Feb 2024

Immune Response To Sars-Cov-2 Variants After Immunization With Different Vaccines In Mexico, Erika Garay, Sean P J Whelan, Rebecca M Dubois, Sara M O'Rourke, Angel Eduardo Salgado-Escobar, José Esteban Muñoz-Medina, Carlos F Arias, Susana López

2020-Current year OA Pubs

There is limited information on the antibody responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in subjects from developing countries with populations having a high incidence of co-morbidities. Here, we analysed the immunogenicity of homologous schemes using the ChAdOx1-S, Sputnik V, or BNT162b2 vaccines and the effect of a booster dose with ChAdOx1-S in middle-aged adults who were seropositive or seronegative to the SARS-CoV-2 spike protein before vaccination. The study was conducted post-vaccination with a follow-up of 4 months for antibody titre using enzyme-linked immunosorbent assay (ELISA) and pseudovirus (PV) neutralization assays (PNAs). All three vaccines elicited a superior …


Sexuality Research During A National Lockdown: Reflexive Notes And Lessons From My Ph.D. Fieldwork, Tshepo B. Maake Mr Feb 2024

Sexuality Research During A National Lockdown: Reflexive Notes And Lessons From My Ph.D. Fieldwork, Tshepo B. Maake Mr

The Qualitative Report

The COVID-19 pandemic presented challenges for qualitative researchers since many countries had to implement lockdown policies to control the spread of the virus. Within the South African context, research on sexual minority identities and experiences is automatically sensitive and risky given the extent of intolerance and high regard for heteronormative ideologies and beliefs that continually exclude sexual minorities from the “normal.” The sensitivity is intensified during a national lockdown since there is an excessive reliance on digital public spaces to recruit participants and conduct interviews. Based on the experience of Ph.D. fieldwork, this paper pays attention to a sexuality researcher’s …