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COVID-19

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Hospital Strain During The Covid-19 Pandemic And Outcomes In Older Racial And Ethnic Minority Adults, Laurent G Glance, Karen E Joynt Maddox, Patricia W Stone, E Yoko Furuya, Jingjing Shang, Mark J Sorbero, Ashley Chastain, Stewart J Lustik, Andrew W Dick Oct 2024

Hospital Strain During The Covid-19 Pandemic And Outcomes In Older Racial And Ethnic Minority Adults, Laurent G Glance, Karen E Joynt Maddox, Patricia W Stone, E Yoko Furuya, Jingjing Shang, Mark J Sorbero, Ashley Chastain, Stewart J Lustik, Andrew W Dick

2020-Current year OA Pubs

IMPORTANCE: Marginalized populations have been disproportionately affected by the COVID-19 pandemic. Critically ill patients belonging to racial and ethnic minority populations treated in hospitals operating under crisis or near-crisis conditions may have experienced worse outcomes than White individuals.

OBJECTIVE: To examine whether hospital strain was associated with worse outcomes for older patients hospitalized with sepsis and whether these increases in poor outcomes were greater for members of racial and ethnic minority groups compared with White individuals.

DESIGN, SETTING, AND PARTICIPANTS: In this cross-sectional study, multivariable regression analysis was conducted to assess differential changes in all-cause 30-day mortality and major morbidity …


High Fat, High Sucrose Diet Promotes Increased Expression Of Ace2 Receptor In The Siv-Infected Host: Implications For Sars-Cov-2 Infection, Elizabeth C. Delery, Danielle E. Levitt, Angela M. Amedee, Patricia E. Molina, Liz Simon Sep 2024

High Fat, High Sucrose Diet Promotes Increased Expression Of Ace2 Receptor In The Siv-Infected Host: Implications For Sars-Cov-2 Infection, Elizabeth C. Delery, Danielle E. Levitt, Angela M. Amedee, Patricia E. Molina, Liz Simon

School of Graduate Studies Faculty Publications

Introduction: People with pre-existing conditions, including metabolic comorbidities, are at greater risk for complications of SARS-CoV-2 infection and expression of machinery required for viral entry into host cells may be a contributing factor. This study tested the hypothesis that high fat, high sucrose diet (HFSD) and alcohol use increase expression of angiotensin converting enzyme 2 (ACE2) receptor and transmembrane serine protease 2 (TMPRSS2) in tissues isolated from simian immunodeficiency virus (SIV) infected macaques, the most clinically relevant model for the study of HIV. Methods: Biospecimens obtained from a longitudinal study of SIV-infected, antiretroviral therapy (ART)-treated female rhesus macaques (Macaca mulatta) …


Impact Of Covid-19 Lockdown On Patient-Provider Electronic Communications, Michael A Hansen, Rebecca Chen, Jacqueline Hirth, James Langabeer, Roger Zoorob Sep 2024

Impact Of Covid-19 Lockdown On Patient-Provider Electronic Communications, Michael A Hansen, Rebecca Chen, Jacqueline Hirth, James Langabeer, Roger Zoorob

Faculty, Staff and Students Publications

BACKGROUND: SARS CoV-2 virus (COVID-19) impacted the practice of healthcare in the United States, with technology being used to facilitate access to care and reduce iatrogenic spread. Since then, patient message volume to primary care providers has increased. However, the volume and trend of electronic communications after lockdown remain poorly described in the literature.

METHODS: All incoming inbox items (telephone calls, refill requests, and electronic messages) sent to providers from patients amongst four primary care clinics were collected. Inbox item rates were calculated as a ratio of items per patient encountered each week. Trends in inbox rates were assessed during …


Covid-19 And Health Equity: Lessons Learned From The Pandemic, Sumaya Ali, Lakell Archer, Erica L. Jensen Sep 2024

Covid-19 And Health Equity: Lessons Learned From The Pandemic, Sumaya Ali, Lakell Archer, Erica L. Jensen

Journal of Nonprofit Innovation

Health inequities refer to avoidable, unjust differences in health outcomes caused by systemic disadvantages rooted in social, economic, and environmental contexts (Braveman, 2014). Health disparities refer to differences in health outcomes between groups, often measured by prevalence, morbidity, or mortality (Centers for Disease Control and Prevention [CDC], 2020). Health inequalities are measurable differences in health status that may arise from biological, social, or environmental factors (World Health Organization [WHO], 2019). Health inequities, however, are specifically preventable and unjust differences.

The COVID-19 pandemic highlighted these inequities, intensifying pre-existing structural disparities within healthcare and societal systems. The pandemic underscored the urgency of …


A Basally Active Cgas-Sting Pathway Limits Sars-Cov-2 Replication In A Subset Of Ace2 Positive Airway Cell Models, Maritza Puray-Chavez, Jenna E Eschbach, Ming Xia, Kyle M Lapak, Qianzi Zhou, Ria Jasuja, Jiehong Pan, Jian Xu, Zixiang Zhou, Shawn Mohammed, Qibo Wang, Dana Q Lawson, Sanja Djokic, Gaopeng Hou, Siyuan Ding, Steven L Brody, Michael B Major, Dennis Goldfarb, Sebla B Kutluay Sep 2024

A Basally Active Cgas-Sting Pathway Limits Sars-Cov-2 Replication In A Subset Of Ace2 Positive Airway Cell Models, Maritza Puray-Chavez, Jenna E Eschbach, Ming Xia, Kyle M Lapak, Qianzi Zhou, Ria Jasuja, Jiehong Pan, Jian Xu, Zixiang Zhou, Shawn Mohammed, Qibo Wang, Dana Q Lawson, Sanja Djokic, Gaopeng Hou, Siyuan Ding, Steven L Brody, Michael B Major, Dennis Goldfarb, Sebla B Kutluay

2020-Current year OA Pubs

Host factors that define the cellular tropism of SARS-CoV-2 beyond the cognate ACE2 receptor are poorly defined. Here we report that SARS-CoV-2 replication is restricted at a post-entry step in a number of ACE2-positive airway-derived cell lines due to tonic activation of the cGAS-STING pathway mediated by mitochondrial DNA leakage and naturally occurring cGAS and STING variants. Genetic and pharmacological inhibition of the cGAS-STING and type I/III IFN pathways as well as ACE2 overexpression overcome these blocks. SARS-CoV-2 replication in STING knockout cell lines and primary airway cultures induces ISG expression but only in uninfected bystander cells, demonstrating efficient antagonism …


Making (Virtual) Space For Disability Equity In Academia, Melissa Vosen Callens, Cali Anicha, Larry Napoleon Jr. Sep 2024

Making (Virtual) Space For Disability Equity In Academia, Melissa Vosen Callens, Cali Anicha, Larry Napoleon Jr.

Feminist Pedagogy

Virtual or hybrid options provide a way for marginalized faculty and staff to fully participate in their fields and on their campuses. As such, an equitable and pandemic-informed academic workplace should include fully accessible and well-resourced hybrid participation options for department meetings and events, office work, and classroom duties. In spring 2023, we created a work group on our campus to address the challenges of hybrid work and co-create campus-wide recommendations for hybrid workspaces. In this article, we share our findings and evidence-based recommendations, many of which draw on Universal Design for Learning, as well as offer suggestions on how …


Collective Access, Collective Liberation: Disability Justice And Abolitionist Pedagogical Worldmaking Toward Post(?)-Pandemic Futures, Hailey N. Otis Sep 2024

Collective Access, Collective Liberation: Disability Justice And Abolitionist Pedagogical Worldmaking Toward Post(?)-Pandemic Futures, Hailey N. Otis

Feminist Pedagogy

This critical commentary poses the question: what if we didn’t return to the “normal” of strict, ableist classrooms policies rooted in the bureaucratic, legalistic framework of “accommodations” and, instead, embraced the Disability Justice principle of collective access? After critiquing the accommodations process used in most higher education settings, I advocate for an approach we might call collective access pedagogy, which works from the fundamental assumptions that (1) all bodies exist on a spectrum of dis/ability and, thus, we all have individual needs based on our unique bodyminds, and (2) that we don’t need the constant threat of a pandemic to …


Emotional Overeating And Eating Motives During Covid-19 In Polish Women: Intergroup Comparison Among Participants In Various Body Mass Index Categories, Adriana Modrzejewska, Justyna Modrzejewska, Kamila Czepczor-Bernat, Julia Wyszomirska Sep 2024

Emotional Overeating And Eating Motives During Covid-19 In Polish Women: Intergroup Comparison Among Participants In Various Body Mass Index Categories, Adriana Modrzejewska, Justyna Modrzejewska, Kamila Czepczor-Bernat, Julia Wyszomirska

Baltic Journal of Health and Physical Activity

Introduction: Taking into account the situation of the COVID-19 pandemic and the ac-companying lockdown resulting in increased negative emotions, it is interesting to learn about eating motives and behaviors and check their intensity. The aim of this study was to investigate the differences between Polish women in various body mass index categories in terms of eating motives and emotional overeating during the COVID-19 pandemic. Material and methods: This study sample comprised 1,447 women (Mage = 31.34 ± 11.05; MBMI = 23.79 ± 4.59). The research used the following tools: the Eating Motivation Survey, the Emotional Overeating Questionnaire, and …


Nevada’S Housing Policy Landscape: Data, Analysis, And Policy Solutions, Brookings Mountain West, Lied Center For Real Estate Sep 2024

Nevada’S Housing Policy Landscape: Data, Analysis, And Policy Solutions, Brookings Mountain West, Lied Center For Real Estate

Brookings Mountain West Special Events

From rising rents to high interest rates to limited supply, housing policy is a central issue in the 2024 elections. Brookings Mountain West, in partnership with UNLV’s Lied Center for Real Estate, hosted a community forum examining the local, state, and federal impacts of Nevada’s housing challenges. New research presented at the forum offer insights into the demographic and economic dynamics of individuals and families navigating Nevada's turbulent housing market, assess trends in home ownership, and evaluate barriers preventing Nevadans from accessing the housing market.


Optimization Of Cellular Transduction By The Hiv-Based Pseudovirus Platform With Pan-Coronavirus Spike Proteins, Syamala Rani Thimmiraju, Maria Jose Villar, Jason T Kimata, Ulrich Strych, Maria Elena Bottazzi, Peter J Hotez, Jeroen Pollet Sep 2024

Optimization Of Cellular Transduction By The Hiv-Based Pseudovirus Platform With Pan-Coronavirus Spike Proteins, Syamala Rani Thimmiraju, Maria Jose Villar, Jason T Kimata, Ulrich Strych, Maria Elena Bottazzi, Peter J Hotez, Jeroen Pollet

Faculty, Staff and Students Publications

Over the past three years, new SARS-CoV-2 variants have continuously emerged, evolving to a point where an immune response against the original vaccine no longer provided optimal protection against these new strains. During this time, high-throughput neutralization assays based on pseudoviruses have become a valuable tool for assessing the efficacy of new vaccines, screening updated vaccine candidates against emerging variants, and testing the efficacy of new therapeutics such as monoclonal antibodies. Lentiviral vectors derived from HIV-1 are popular for developing pseudo and chimeric viruses due to their ease of use, stability, and long-term transgene expression. However, the HIV-based platform has …


An Exploration Of Turnover Intentions Of Substance Abuse Treatment Rns During The Covid-19 Pandemic: A Qualitative Study, Ciara Patrice Jones Sep 2024

An Exploration Of Turnover Intentions Of Substance Abuse Treatment Rns During The Covid-19 Pandemic: A Qualitative Study, Ciara Patrice Jones

Doctoral Dissertations and Projects

The COVID-19 pandemic has affected nurses working in many different settings. As they were frequently the last personnel left at the frontline during COVID-19, nurses’ experiences provide distinctive narratives in the alcohol and other drug treatment workforce. Since the COVID-19 pandemic, nurses working in a substance abuse treatment setting have experienced significantly increased stressors, including fear and anxiety, the lack of personal protective equipment (PPE), and a lack of workforce sustainability. Therefore, this generic qualitative study explored the perceptions and experiences of nurses working in a substance abuse treatment program on the barriers in their workforce that influence their turnover …


Exploring Barriers To Effective Covid-19 Risk Mitigation, Recovery, And Chronic Disease Self-Management: A Qualitative Multilevel Perspective, Gayenell S. Magwood Phd, Rn, Faha, Faan, Charles Ellis, Chanita Hughes Halbert, Ebony Allen Toussaint, Jewel Scott Phd, Rn, Fnp-C, Lynne S. Nemeth Sep 2024

Exploring Barriers To Effective Covid-19 Risk Mitigation, Recovery, And Chronic Disease Self-Management: A Qualitative Multilevel Perspective, Gayenell S. Magwood Phd, Rn, Faha, Faan, Charles Ellis, Chanita Hughes Halbert, Ebony Allen Toussaint, Jewel Scott Phd, Rn, Fnp-C, Lynne S. Nemeth

Publications

INTRODUCTION: Many research activities have focused on SARS-CoV-2 infection and subsequent COVID-19 respiratory illness during the pandemic. However, significant racial inequities emerged months after the COVID-19 pandemic began. The similarity between racial/ ethnic disparities in COVID-19 and those for other diseases raised awareness about the context for risk exposure and healthcare access. The purpose of this study is to examine social and structural determinants of health among COVID-19 survivors, carepartners, and the perspectives of healthcare stakeholders who experienced disruption during the early pandemic. MATERIAL AND METHODS: A purposive sample of interviews (n=9) and focus groups (n=10) were used to collect …


Exploring Barriers To Effective Covid-19 Risk Mitigation, Recovery, And Chronic Disease Self-Management: A Qualitative Multilevel Perspective, Gayenell S. Magwood Phd, Rn, Faha, Faan, Charles Ellis Jr, Chanita Hughes Halbert, Ebony Allen Toussaint, Jewel Scott Phd, Rn, Fnp-C, Lynne S. Nemeth Sep 2024

Exploring Barriers To Effective Covid-19 Risk Mitigation, Recovery, And Chronic Disease Self-Management: A Qualitative Multilevel Perspective, Gayenell S. Magwood Phd, Rn, Faha, Faan, Charles Ellis Jr, Chanita Hughes Halbert, Ebony Allen Toussaint, Jewel Scott Phd, Rn, Fnp-C, Lynne S. Nemeth

Faculty Publications

Introduction: Many research activities have focused on SARS-CoV-2 infection and subsequent COVID-19 respiratory illness during the pandemic. However, significant racial inequities emerged months after the COVID-19 pandemic began. The similarity between racial/ ethnic disparities in COVID-19 and those for other diseases raised awareness about the context for risk exposure and healthcare access. The purpose of this study is to examine social and structural determinants of health among COVID-19 survivors, carepartners, and the perspectives of healthcare stakeholders who experienced disruption during the early pandemic.
Material and methods: A purposive sample of interviews (n=9) and focus groups (n=10) were used to collect …


Post-Covid-19: The Effect Of Social Anxiety On The Continued Wearing Of Face Masks In Saudi Arabia, بسمة بيانوني Sep 2024

Post-Covid-19: The Effect Of Social Anxiety On The Continued Wearing Of Face Masks In Saudi Arabia, بسمة بيانوني

Journal of King Abdulaziz University: Educational and Psychological Sciences

ملخص: قد يرتدي الأفراد الذين يعانون من القلق الاجتماعي كمامة الوجه كسلوك أمان، مما قد يؤدي إلى الالتزام لفترة طويلة بالكمامة وعدم خلعها، حتى بعد انتهاء من جائحة كوفيد-19. في هذا البحث تم توزيع استبيان عبر الإنترنت على عينة ملائمة مكونة من 370 مواطنًا. وتضمن الاستبيان مقياس القلق الاجتماعي ثلاثي الأبعاد (المعرفي والاجتماعي والجسدي) لتقييم مستويات القلق الاجتماعي، بالإضافة إلى سؤال مفتوح لقياس الميل إلى الاستمرار في ارتداء الكمامات بعد الجائحة. لم يتم العثور على ارتباطات ذات دلالة إحصائية بين القلق الاجتماعي وارتداء القناع على الأبعاد المعرفية أو الاجتماعية أو على المقياس بشكل عام. ومع ذلك لوحظت علاقات ذات دلالة …


The Impact Of Covid-19 On Higher Education Enrollment, Samuel Tanner Mcknight Sep 2024

The Impact Of Covid-19 On Higher Education Enrollment, Samuel Tanner Mcknight

Student Theses and Dissertations

Impacts to postsecondary institutions’ enrollment and financial positions that resulted from the COVID-19 pandemic were examined in this study. Taking a quantitative observational approach, enrollment trends as they relate to changes in tuition and fee revenue, unrestricted cash on hand, and unrestricted investments held are analyzed to determine the extent of exposure faced by postsecondary institutions caused by the COVID-19 pandemic. Using the results from this statistical analysis, the need for postsecondary institutions to maintain financial contingency funds in the form of liquid reserves are highlighted and emphasized through the lens of Bowen’s revenue theory of cost. The majority of …


Examining The Influence Of Students’ Mental Health Problems On Their Social And Emotional Health: Perspectives Of Counselors And Mental Health Therapists In A Post-Pandemic World, Brandi Leigh Newsom Sep 2024

Examining The Influence Of Students’ Mental Health Problems On Their Social And Emotional Health: Perspectives Of Counselors And Mental Health Therapists In A Post-Pandemic World, Brandi Leigh Newsom

Student Theses and Dissertations

Examining the Influence of Students’ Mental Health Problems on Their Social and Emotional Health: Perspectives of Counselors and Mental Health Therapists in a Post-Pandemic World This qualitative phenomenological study explored the influence mental health issues have on social emotional learning in the public-school setting. The problem addressed in this study was the increased need for mental health resources and awareness in the school setting. By assessing the perspectives of school counselors and mental health therapists, awareness and resources can help students who are struggling with social-emotional needs. The guiding theoretical framework that served as the basis for this study was …


Teacher Perceptions Of Reading And Mathematics Achievement Gaps Among Elementary Students Resulting From The Covid-19 Pandemic, Kayla Lynn Caprio Sep 2024

Teacher Perceptions Of Reading And Mathematics Achievement Gaps Among Elementary Students Resulting From The Covid-19 Pandemic, Kayla Lynn Caprio

Student Theses and Dissertations

The purpose of this descriptive qualitative case study was to discover Second through Fifth Grade rural North Texas teacher perceptions focusing on reading and mathematics student achievement gaps resulting from the COVID-19 pandemic. This study explores how the COVID-19 pandemic shutdown affected students not only academically but also socially as well. Through a qualitative case study design, this study collected qualitative data by interviewing seven-Second through Fifth Grade teachers through semi-structured interviews, a focus group, and MAP data by analyzing MAP data collected in the beginning and middle of the year from the 2019-2023 school years. The social learning theory …


Design Thinking Strategies For Complex Situations: Covid-19 In Western Australia And New South Wales, Terence Love, Paul Cozens, Trudi Cooper Sep 2024

Design Thinking Strategies For Complex Situations: Covid-19 In Western Australia And New South Wales, Terence Love, Paul Cozens, Trudi Cooper

Research outputs 2022 to 2026

This paper outlines an argument for changing the foundation of design thinking practices to include causal feedback loops instead of primarily predicting futures using linear causal relations. The paper suggests for most real-world design situations the traditional linear causal perspective is insufficient and leads to lower value design outcomes. The authors propose instead designers address real-world complex design situations via design methods that include feedback loops, which require different design methods and tools. The discussion in the paper follows the understanding of systems researchers. The authors provide an example of the significant differences in outcomes using a comparative case study …


A Case Study: Do You Address Your Volunteers’ Well-Being Or Mental Health During The Covid-19 Pandemic? If So, How?, Daniel J. Robotham, Suzanna R. Windon, Ann E. Echols Sep 2024

A Case Study: Do You Address Your Volunteers’ Well-Being Or Mental Health During The Covid-19 Pandemic? If So, How?, Daniel J. Robotham, Suzanna R. Windon, Ann E. Echols

Journal of Extension

The uncertainty caused by the COVID-19 pandemic had a profound negative impact on volunteer mental health and well-being. We surveyed local non-profit organizational leaders about their practices toward addressing volunteer well-being and mental health during the COVID-19 pandemic. Study results indicated that while over a quarter of organizations did nothing to address volunteer well-being, other organizations utilized several approaches, including one-on-one and group meetings, program implementation, office culture investment, task assignment, and information dissemination. These findings provide valuable insight for Extension educators to develop community mental health and well-being programs to assist non-profit organizations' response to future uncertainty.


Applying A Framework Of Epistemic Injustice To Understand The Impact Of Covid-19 On People With Intellectual And Developmental Disabilities, Sarah Lineberry, Matthew Bogenschutz Sep 2024

Applying A Framework Of Epistemic Injustice To Understand The Impact Of Covid-19 On People With Intellectual And Developmental Disabilities, Sarah Lineberry, Matthew Bogenschutz

Developmental Disabilities Network Journal

Epistemic injustice, the theory of unfairness related to knowledge, is a useful framework for understanding the ways in which historic and ongoing marginalization and stereotypes have shaped the ways that people with intellectual and developmental disabilities (IDD) have been impacted by the COVID-19 pandemic. We conducted a scoping review of the literature and divided findings into physical health (cases, hospitalization, and death) and psychosocial outcomes (access to services, mental health symptoms, community participation, etc.). Impacts were then analyzed using the key principles of epistemic injustice. Findings suggest that people with intellectual and developmental disabilities (IDD) experienced high rates of negative …


News Frames For Covid-19 – A Comparison Of Australian (Australian Broadcasting Corporation) And Vietnamese (Tuoi Tre Online) Online News Services In Two Key Weeks In 2020, Viet T. Le, Lelia Green Sep 2024

News Frames For Covid-19 – A Comparison Of Australian (Australian Broadcasting Corporation) And Vietnamese (Tuoi Tre Online) Online News Services In Two Key Weeks In 2020, Viet T. Le, Lelia Green

Research outputs 2022 to 2026

This article investigates the differences and similarities between the news frames used by online mainstream media in Vietnam and Australia when reporting COVID-19 in the early waves of the pandemic. The project uses constant comparative analysis to interrogate data gathered from two online news sources: ABC Online (Australian Broadcasting Corporation) in Australia, and Tuoi Tre Online in Vietnam. The article concludes that the Australian Broadcasting Corporation coverage focuses more on social, political and economic factors than is the case with Tuoi Tre Online, which foregrounds civic responsibility in response to the COVID-19 epidemic. The Australian Broadcasting Corporation highlights how COVID-19 …


Wstrzymanie Na Podstawie Art. 31za Ustawy Z 2 Marca 2020 R. O Szczególnych Rozwiązaniach Związanych Z Zapobieganiem, Przeciwdziałaniem I Zwalczaniem Covid-19, Innych Chorób Zakaźnych I Wywoływanych Nimi Sytuacji Kryzysowych Biegu Terminów Dokonania Czynności Przez Komisję Nadzoru Finansowego W Ramach Nadzoru Nad Rynkiem Finansowym, Joanna Róg-Dyrda Sep 2024

Wstrzymanie Na Podstawie Art. 31za Ustawy Z 2 Marca 2020 R. O Szczególnych Rozwiązaniach Związanych Z Zapobieganiem, Przeciwdziałaniem I Zwalczaniem Covid-19, Innych Chorób Zakaźnych I Wywoływanych Nimi Sytuacji Kryzysowych Biegu Terminów Dokonania Czynności Przez Komisję Nadzoru Finansowego W Ramach Nadzoru Nad Rynkiem Finansowym, Joanna Róg-Dyrda

internetowy Kwartalnik Antymonopolowy i Regulacyjny (internet Quarterly on Antitrust and Regulation)

The aim of this article is to analyze the issue of suspending deadlines for actions to be taken by the Polish Financial Supervision Authority in the area of financial supervision based on Article 31za of the Act of 2 March 2020 on Special Solutions Related to the Prevention, Counteracting and Combating COVID-19, Other Infectious Diseases, and Crisis Situations Caused by them (Covid-19 Act). The article focuses on interpretive doubts that have arisen in jurisprudence and the effects of regulations on legal certainty.


Cystic Fibrosis-Related Diabetes Screening At A Large Pediatric Center, Anil K Chokkalla, Pamela Tuley, Miray Kurtca, Herda Ona, Fadel E Ruiz, Sridevi Devaraj Sep 2024

Cystic Fibrosis-Related Diabetes Screening At A Large Pediatric Center, Anil K Chokkalla, Pamela Tuley, Miray Kurtca, Herda Ona, Fadel E Ruiz, Sridevi Devaraj

Faculty, Staff and Students Publications

Objective: Cystic Fibrosis Foundation guidelines recommend annual diabetes screening by oral glucose tolerance test (OGTT) in pediatric patients with cystic fibrosis (CF) starting at the age of 10 years. Adherence to these guidelines proves to be challenging, and the nationwide screening rates are still considered suboptimal. The aim of this study was to assess and improve the screening rates at our large pediatric center.

Methods: A 4-year retrospective audit of OGTT completion among pediatric patients with CF of age ≥10 years who are not yet diagnosed with diabetes was conducted. A collaborative working group was formed to identify the barriers …


A Survey Of Early-Career Speech-Language Pathologists: Determining Perceived Readiness For Clinical Management Of Adults With Dysphagia After Completing Graduate School, Christine A. Lee, Ashwini Namasivayam-Macdonald, Zuleikha Wadhwaniya, Juliana Mclaren, Rebecca H. Affoo Sep 2024

A Survey Of Early-Career Speech-Language Pathologists: Determining Perceived Readiness For Clinical Management Of Adults With Dysphagia After Completing Graduate School, Christine A. Lee, Ashwini Namasivayam-Macdonald, Zuleikha Wadhwaniya, Juliana Mclaren, Rebecca H. Affoo

Teaching and Learning in Communication Sciences & Disorders

Several studies have identified a recurring trend that speech-language pathologists (S-LPs) in countries such as the United States (Caesar & Kitila, 2020), South Africa (Singh et al., 2015), and Malaysia (Kamal et al., 2012) report lower levels of confidence in dysphagia management, whether in comparison to other practice areas or in certain skill areas within the specialty of dysphagia. No data currently exists exploring self-perceptions of Canadian S-LP graduates with regards to clinical management of adults with dysphagia. Therefore, the purpose of this study was to determine the self-reported readiness of recently graduated Canadian S-LPs who manage dysphagia. Our survey …


The Il-6 Hypothesis In Covid-19: A Phase 2, Randomised, Double-Blind, Placebo-Controlled Study To Evaluate The Efficacy And Safety Of Free Il-6 Sequestration By The Monoclonal Antibody Sirukumab In Severe And Critical Covid-19, Robert L. Gottlieb, Meredith Clement, Paul Cook, Audra Deveikis, Kap Sum Foong, Philip Robinson, Jihad Slim, Cedric W. Spak, Annemie Buelens, Katleen Callewaert, Sandra De Meyer, Wai Ling Mo, Inge Verbrugge, Liesbeth Van Wesenbeeck, Yanli Zhuang, Jason W. Chien, Magda Opsomer, Erika Van Landuyt Sep 2024

The Il-6 Hypothesis In Covid-19: A Phase 2, Randomised, Double-Blind, Placebo-Controlled Study To Evaluate The Efficacy And Safety Of Free Il-6 Sequestration By The Monoclonal Antibody Sirukumab In Severe And Critical Covid-19, Robert L. Gottlieb, Meredith Clement, Paul Cook, Audra Deveikis, Kap Sum Foong, Philip Robinson, Jihad Slim, Cedric W. Spak, Annemie Buelens, Katleen Callewaert, Sandra De Meyer, Wai Ling Mo, Inge Verbrugge, Liesbeth Van Wesenbeeck, Yanli Zhuang, Jason W. Chien, Magda Opsomer, Erika Van Landuyt

School of Medicine Faculty Publications

Background: Upregulation of IL-6 has been associated with worse prognosis in COVID-19 patients. Impact on IL-6 signalling has mostly been limited to clinical outcomes in IL-6 receptor antagonist trials. Methods: We performed a phase 2, randomised, double-blind, placebo-controlled trial (NCT04380961) of US-based hospitalised adults (< 85 years) with laboratory-confirmed SARS-CoV-2 infection and severe (low levels of supplemental oxygen) or critical disease (high levels of oxygen supplementation). Patients received sirukumab 5 mg/kg or placebo single dose IV on Day 1 plus standard of care. The primary endpoint was time to sustained clinical improvement up to Day 28 based on an ordinal scale. Secondary endpoints included clinical improvement, all-cause mortality, and safety. Following an interim analysis, the protocol was amended to only recruit patients with critical COVID-19. Findings: From May 2020 to March 2021, 209 patients were randomised; 112 had critical disease (72 sirukumab, 40 placebo) at baseline. Median time to sustained clinical improvement in critical patients was 17 and 23 days in the sirukumab and placebo groups (HR, 1∙1; 95% CI, 0∙66–1∙88; p > 0∙05). At Day 28, 59∙4% versus 55∙0% of patients achieved clinical improvement with sirukumab versus placebo and rates of all-cause mortality were 24∙6% versus 30∙0%, respectively. Rates of grade ≥ 3 adverse events were comparable between the sirukumab and placebo groups (25∙9% vs 32∙9%; all patients). Interpretation: In critical COVID-19 patients who received sirukumab, there …


A Comparative Study Of Indonesia And Malaysia's Economic Resilience In The Covid-19 Era: An Analysis Of Economic Stability, Muhammad Nur Abdul Latif Nur Latif Al Waroi Sep 2024

A Comparative Study Of Indonesia And Malaysia's Economic Resilience In The Covid-19 Era: An Analysis Of Economic Stability, Muhammad Nur Abdul Latif Nur Latif Al Waroi

Jurnal Kajian Stratejik Ketahanan Nasional

This study analyzes the economic resilience of Indonesia and Malaysia during the COVID-19 pandemic, focusing on economic stability. The research explores pre-pandemic economic conditions, the impact of COVID-19 on GDP, inflation, unemployment, and government debt, as well as recovery efforts through fiscal and monetary policies. Data from Statistics Indonesia, Department of Statistics Malaysia, World Bank, and IMF were used. Results indicate that Indonesia experienced a faster economic recovery, with GDP growth returning to pre-pandemic levels quicker than Malaysia. The economic impact of the pandemic in Indonesia is lower, supported by the National Economic Recovery Program (PEN) and Bank Indonesia's monetary …


Covid-19 Implications On Worksite Wellness Programming, Renee A. Underwood, Angela R. Wood, Ralph J. Wood, Rylie B. Broussard, Stephanie T. Broyles Sep 2024

Covid-19 Implications On Worksite Wellness Programming, Renee A. Underwood, Angela R. Wood, Ralph J. Wood, Rylie B. Broussard, Stephanie T. Broyles

Population and Public Health Science Faculty Publications

Seven of the top ten leading causes of death in the United States are due to chronic diseases and treating these accounts for 86 percent of our nation's health care costs. The workplace offers an environment to implement chronic disease prevention strategies, such as worksite wellness programs, due to the large amount of time spent at the worksite daily by employees. As a result of COVID-19, many organizations began to change their workdays (i.e., working from home). This research sought to understand what, if any, implications the COVID-19 epidemic had on worksite wellness programming. Semistructured interviews were employed and recorded …


Changes In Psychological Challenges, Positive Experiences, And Coping Strategies Among International Students In The United States Before And During The Covid-19 Pandemic: A Qualitative Study, Chulwoo Park, Shannon Shimada, Airi Irene Trisnadi, Patricia Angelica Sep 2024

Changes In Psychological Challenges, Positive Experiences, And Coping Strategies Among International Students In The United States Before And During The Covid-19 Pandemic: A Qualitative Study, Chulwoo Park, Shannon Shimada, Airi Irene Trisnadi, Patricia Angelica

Faculty Research, Scholarly, and Creative Activity

The purpose of this study was to understand how the challenges and coping strategies among international students in the United States changed before and during the COVID-19 pandemic. We conducted a qualitative study through one-on-one in-depth interviews during April–June 2021. A total of 34 international students in the San Francisco Bay Area participated in this study. NVivo was used to analyze the qualitative data. Before COVID-19, the challenges were primarily related to a sense of belonging, such as culture shock, language barriers, and loss of identity. However, some positive experiences from school life and new culture were also found before …


Trends In The Incidence Of Hypertensive Disorders Of Pregnancy Among The Medicaid Population Before And During Covid-19, Jessica Lin, Heidi Feng, Ronald Horswell, San Chu, Yun Shen, Gang Hu Sep 2024

Trends In The Incidence Of Hypertensive Disorders Of Pregnancy Among The Medicaid Population Before And During Covid-19, Jessica Lin, Heidi Feng, Ronald Horswell, San Chu, Yun Shen, Gang Hu

Population and Public Health Science Faculty Publications

Importance: Hypertensive disorders of pregnancy (HDP) are a group of high blood pressure disorders during pregnancy that are a leading cause of maternal and infant morbidity and mortality. Data on the trend in the incidence of HDP among the Medicaid population during coronavirus disease of 2019 (COVID-19) are lacking. Objective: To determine the trends in the annual incidence of HDP among pregnant Medicaid-insured women in Louisiana before and during the COVID-19 pandemic (2016–2021). Methods: A total of 113,776 pregnant women aged 15–50 years were included in this study. For multiparous individuals, only the first pregnancy was used in the analyses. …


Impact Of Sars-Cov-2 (Covid-19) Infections On Mental Health Diagnoses In Youth With Chronic Illness, Molly Mcvoy, Rina Hung, Irina Bransteter, David W. Miller, Jeffrey A. Dusek, Martha Sajatovic Sep 2024

Impact Of Sars-Cov-2 (Covid-19) Infections On Mental Health Diagnoses In Youth With Chronic Illness, Molly Mcvoy, Rina Hung, Irina Bransteter, David W. Miller, Jeffrey A. Dusek, Martha Sajatovic

Faculty Scholarship

Objective: Stressors from the COVID-19 pandemic and limited availability of mental health care services have negatively impacted youth mental health in a significant way. In the first year of the pandemic, global prevalence of anxiety and depression increased by roughly 25% in pediatric populations. While the general trend is clear, this research aimed to explore the added mental health burden of acute COVID-19 on pediatric patients with chronic conditions and describe the differences in mental health outcomes between pediatric patients with 2 common chronic conditions (asthma and diabetes) to better understand specific factors that may increase susceptibility to mental health …