Digital Commons Network^™

Comparison Of Ecg Features, Cardiac Biomarkers, And Clinical Outcomes In Three Waves Of Hospitalized Covid-19 Pneumonia Patients With Cardiovascular Events, Yuchen Han, Jahnavi Sunkara, Tshura S Ali, Harideep Samanapally, Vidyulata Salunkhe, Fnu Deepti, Emma C. Huang, Justin J. Huang, Maiying Kong, Jiapeng Huang

The University of Louisville Journal of Respiratory Infections

Background

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a rapidly evolving virus that can severely impact the cardiovascular system. With new variants, it is important to characterize wave-specific (defined by dominant circulating variants) clinical changes.

Methods

A multi-center retrospective cohort study of patients hospitalized with SARS-CoV-2 community acquired pneumonia at eight adult acute-care hospitals in the city of Louisville, KY was conducted. Patients hospitalized with Coronavirus Disease 2019 (COVID-19) community acquired pneumonia who experienced a cardiovascular event between March 2020 and July 2022 were included in this analysis. Variant assignment was based on temporal prevalence rather than genomic confirmation, and …

International Spillover: How External, Global Events Such As Brexit And Covid-19 Have Impacted Housing Prices Within The Republic Of Ireland, Allie Riggs

Undergraduate Honors Thesis Collection

The housing market in Ireland has experienced such a great crisis in recent history that over a third of residents have considered moving to a more affordable country (Hogg, 2024). While a number of both causes and potential solutions have been analyzed in regard to this national crisis, I hypothesize that there has been a greater shock from external, global events in the COVID-19 pandemic and Brexit. In performing a regression on secondary data while controlling for macroeconomic factors that impact the housing market, I have identified a positive, significant association between these two exogenous shocks and their impact on …

An Integrated Framework For Early Detection And Transmissibility Assessment Of Emerging Variants In Wastewater, Xingwen Chen, Tin Phan, Wei Lin Lee, Katie Clark, Steven F Rhode, Samantha Brozak, Bruce Pell, Tsultrim Palden, Mats Leifels, Anna Gitter, Yang Kuang, Stefan Wuertz, Janelle Thompson, Kristina D Mena, Eric J Alm, Fuqing Wu

Faculty, Staff and Student Publications

Tracking the emergence of new viral variants is critical for epidemic preparedness, but remains challenging because variants typically circulate at low prevalence during the early phase of outbreaks. Here, we present an integrated framework that combines sensitive variant detection in wastewater with quantitative assessment of transmissibility through dynamic epidemic modeling. Using the SARS-CoV-2 Omicron variant as a proof of concept, we developed a novel nested allele-specific RT-qPCR assay (NAS-PCR) that achieved a thousand-fold increase in sensitivity compared with allele-specific RT-qPCR (limit of detection: 0.5 copies/μl). NAS-PCR detected Omicron in wastewater samples from the Greater Boston area starting in September 2021, …

The Impact Of Covid-19 On Spine Surgery: Temporal Trends In Complications And Patient-Reported Outcomes Across A Statewide Cohort, Ali Mehaidli, Richard Easton, Ahmad Almaat, Gary George, Alqasim Elnaggar, Victor Chang, Doris Tong, Jad Khalil, Kevin Taliaferro

Conference Presentation Abstracts

Introduction: The COVID-19 pandemic caused major disruptions in elective surgical care, including spine surgery, due to widespread hospital restructuring and resource limitations. Although previous studies have examined surgical volumes and safety during the pandemic, limited data exist on how outcomes varied across multiple phases of the pandemic, especially in real-world, multicenter spine surgery populations. Material and Methods: This retrospective cohort study used data from the Michigan Spine Surgery Improvement Collaborative (MSSIC) to compare outcomes in patients undergoing lumbar or cervical spine surgery across four COVID-19 timeframes: pre-COVID (1/2019-2/2020), onset-COVID (3/2020-9/2020), active-COVID (10/2020-2/2022), and post-COVID (3/2022- 12/2022). Patient demographics, surgical characteristics, …

Rethinking Covid-19 Tourism Recovery, Anestis Fotiadis, Efstathios Polyzos, Tzung Cheng Huan

All Works

No abstract provided.

A Phenomenological Study On The Experiences Of Educators As Mentors For Homeless And Highly Mobile Students In A Rural Community, Tracy Dawn Mcpheron

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study is to explore how educators perceive an implemented mentoring program in which they will serve as mentors of homeless and highly mobile students in a rural school district. The mentoring program will include educators working as mentors to students coded as homeless through the McKinney-Vento Act for Homeless Education. The educators participating in the mentoring program will be the participants in this study. The participants will include middle school (6th-8th grade) through high school (12th grade), teachers, counselors, librarians, the district’s homeless liaison, and the federal programs coordinator for an East Tennessee school …

Capitalizing On Crisis: A Statistical Analysis Of Federal Funding And The Surge In White-Collar Criminal Activity During The Covid-19 Pandemic, Lee R. Gibson

Doctoral Dissertations and Projects

The COVID-19 pandemic ushered in a new era that has forever changed how people work, communicate, and socialize. The pandemic also brought one of the most significant influxes of financial assistance to individuals, businesses, educational institutions, and state and local governments that has ever been seen. This massive infusion of cash, which was orchestrated and managed by the federal government, was instituted in a manner that provided quick relief with little ability for oversight, resulting in every assistance program experiencing high rates of fraudulent activity. This project aims to understand if the levels of white-collar crime increase during a disaster, …

Teachers’ Perceptions Of Social-Emotional Learning Of Special Education Middle School Students, Stephen Thurman

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenological study was to understand the influence COVID-19 and related shutdowns had on middle school special education students' social-emotional learning based on teachers lived experiences at a middle school in north Georgia. At this stage in the research, the influence COVID-19 and related shutdowns had on middle school special education students' social-emotional learning was generally defined as how student social-emotional learning has changed since the COVID-19 pandemic. The theory guiding this study was social cognitive theory, as this theory closely aligns with the topic of the importance of social-emotional learning and how students attain social-emotional …

Covid Minds: A Thematic Review Of The Pandemic On Neural Mechanisms And Political Polarization, Madison Jeffries

Honors Projects

This paper analyzes how the COVID-19 pandemic influenced political polarization in the United States by examining the interactions between social system disruption, psychological stress, and underlying neurological behaviors. While previous research has extensively discussed pandemic's influence on public health and societal breakdowns, studies fail to examine how these disruptions shaped political divisions. This study synthesizes interdisciplinary literature on pandemic-induced stressors and analyzes factors, including institutional mistrust and social isolation, and how these experiences shape political behavior and perspectives. Applying research from psychology and neuroscience, the paper argues that prolonged exposure to pandemic-related stressors changed neurological and behavioral patterns in response …

Testimonios De Una Estudiante De Doctorado: Regaining Joy In Graduate School Through Research-Practice Partnerships, Sophia Piral Lee

The Qualitative Report

Through an epistolary critical autoethnography and Latina and Chicana feminist framework, I explore the question of how international graduate students of color can overcome cultural, linguistic, ethnoracial, and social class isolation on predominantly white campuses and in college towns. By writing a letter to my mother (one of my methods for survival in academia), I share my challenges as a Guatemalan, first-time mom, first-generation college student, international student, and non-English native speaker in graduate school during and after the COVID-19 pandemic. At the same time, this writing helps me recognize how I overcame my isolation and regained my joy and …

First Covid-19 Vaccination Rates Among Pregnant Tennessee Women By Month Of Conception And Urbanization Level: March 2021 – November 2021, Claudia Valenzuela, Anne K. Driscoll, Elizabeth Harvey, Heather Wingate

Journal of Appalachian Health

Introduction: Throughout the pandemic, COVID-19 vaccination coverage was lower for the general population living in rural counties than in urban counties. In Tennessee (TN), COVID-19 vaccinations became available to pregnant women in March 2021. Little is known about rates of COVID-19 vaccination in pregnancy during the pandemic, or whether these rates changed or differed by urbanization level.

Purpose: The purpose of this study is to describe COVID-19 vaccination rates among pregnant women in TN by month of conception and urbanization level.

Methods: COVID-19 vaccination data from the TN Immunization Information System and the TN Surveillance for Emerging Threats to Mothers …

Rethinking Consumer Data And Behavior, Nicole J. Olynk Widmar, Michael L. Smith, Erin Robinson

Purdue University Press Books

Today’s food and agricultural consumers are driven by more than just price—they are influenced by trust, values, and perceptions that are often difficult to measure. Rethinking Consumer Data and Behavior explores what truly shapes consumer choices and how businesses can respond effectively.

This book utilizes research on loyalty, risk, sustainability, and ethical considerations, revealing how these factors influence purchasing decisions in ways traditional data often misses. It examines consumers’ willingness to pay for local and organic products, the impact of food labeling and safety messaging, and the surprising role of sensory cues such as appearance and taste. The book also …

An Examination Of Hiring Practices And Employee Retention Today Compared With Pre-Pandemic Characteristics In Orthodontics, Logan Passey Dds, Msd, Bhavna Shroff Dds, M.D.Sc., Mpa, Christina B. Philips Dds, Msd, Caroline K. Carrico Ph.D., Steven J. Lindauer Dmd, M.D.Sc, Daniel R. Hawkins Dmd, Siddharth Chiang Dds

Virginia Dental Journal

The COVID-19 pandemic resulted in a fundamental shift in the labor market, leading to unprecedented job losses. Between February and April 2020, approximately 22.2 million jobs were lost nationwide. Notably, dentistry was among the top ten industries impacted, accounting for 555,000 of those job losses. When positions were reopened, only 76% of all employees across all industries returned to work by August 2020.

As the COVID-19 pandemic dramatically disrupted workforce stability, particularly within dental practices, effective talent management emerged as a critical strategy for rebuilding and sustaining the dental workforce. Talent management is of increasing importance in today’s labor market, …

Challenges In The Ethical Review Process Of Covid-19 Related Research At Hrec-Tumed, Thailand, Wilaiwan Chimkhong, Thana Khawcharoenporn, Pacharapan Surapolchai

Asian Medical Journal and Alternative Medicine

Objective: To explore the challenges encountered in the ethical review process and timeline of COVID-19 related research at the Human Research Ethics Committee of Thammasat University (Medicine) (HREC-TUMED), Thailand, focusing on submission characteristics, review outcomes, and committee adaptations.

Materials and Methods: This retrospective descriptive study analyzed COVID-19 research protocols submitted to HREC-TUMED between June 2020 and July 2022. Protocols were evaluated for research types, investigator affiliations, funding sources, review types, and timeline metrics, using descriptive statistics.

Results: A total of 89 COVID-19 related research protocols were submitted to HREC-TUMED, with the majority originating from faculty investigators (64%). Most protocols underwent …

Global Apparel Companies Adjusting Their Supply Chain Strategies To Post-Covid-19, Alan D. Smith

Atlantic Marketing Association Proceedings

No abstract provided.

Factors Related To Self-Care Behaviors Among Older Adults For Communicable Disease (Cd) Protection In The Eastern Economic Corridor (Eec) Of Thailand: A Case Study Of Covid-19, Surasingha Sombat Suranartwatchawong, Sane Saengngoen, Supaporn Sudnongbua

Journal of Health Research

Background: The impact of COVID-19 is particularly severe for older adults, who represent the most vulnerable demographic. Using COVID-19 as a case study, this research investigates the factors influencing self-care behaviors for preventing communicable diseases (CD) among older adults in the EEC.

Methods: The study with a cross-sectional design involving 387 older adults aged 60 years was conducted between January and March 2025. The questionnaire was valid and reliable based on objective congruence (IOC) index and Cronbach’s alpha coefficients. Data analysis utilized both descriptive and inferential statistics.  Frequency, percentage, standard deviation, and multiple linear regression analysis were employed …

Bridging The Gap: Perception And Certainty, Elizabeth C. Alexander, Monisha Gupta, Paige Leonard

Atlantic Marketing Association Proceedings

No abstract provided.

The Effect Of Covid-19 On Research Productivity Among Matched Ophthalmic Plastic And Reconstructive Surgery Fellowship Applicants, Andre Galenchik-Chan, Thomas Ren, Kelli Jablon, Aleksandra Krajewski

Journal of Academic Ophthalmology

Background: Ophthalmic plastic and reconstructive surgery (OPRS) is one of the most competitive ophthalmology subspecialities, and scholarly productivity has been regarded as an important criterion for fellowship matching.

Purpose: To calculate changes in research productivity among matched OPRS fellowship candidates amid the COVID-19 pandemic.

Methods: We identified U.S. OPRS fellows who started training from 2020 through 2022 via publicly available fellowship rosters. For each, we extracted gender, training institution, and publication records from PubMed and ResearchGate. We considered peer-reviewed publications before fellowship status. Linear regression analyses were performed to determine correlations between productivity and post-fellowship publication output. …

Vaccination Coverage And Factors Associated With Covid-19 Vaccination In The Adult African American Community In South Carolina: A Cross-Sectional Survey, Brittany Divon Smith

Theses and Dissertations

The COVID-19 pandemic has disproportionately affected African American communities, revealing longstanding disparities in healthcare access and outcomes. In South Carolina, where these inequities are particularly evident, understanding the determinants of COVID-19 vaccine uptake among African Americans is crucial for advancing health equity. This thesis examines vaccination coverage and explores social, economic, and psychological predictors of vaccine uptake in a sample of 305 African American adults through a cross-sectional survey conducted in 2023.

Vaccination status was categorized as unvaccinated, partially vaccinated, and fully vaccinated (with or without a booster). Ordinal logistic regression analyses were performed to examine associations between vaccination status …

Acute Myocardial Infarction In Medicare Beneficiaries During And After The Covid-19 Pandemic, Jonah M Graves, R J Waken, Fengxian Wang, Rishi K Wadhera, Jose F Figueroa, E John Orav, Osvaldo J Laurido-Soto, Karen E Joynt Maddox

2020-Current year OA Pubs

IMPORTANCE: During early months of the COVID-19 pandemic, presentations for acute myocardial infarction (AMI) declined significantly, and outcomes worsened. However, the full extent and long-term sequelae of changes in AMI epidemiology during the pandemic remain uncertain, as does whether these patterns differed by rurality.

OBJECTIVE: To describe the epidemiology of AMI-related hospitalizations, interventions, and outcomes among Medicare beneficiaries throughout the COVID-19 pandemic, focusing on differences in urban and rural populations.

DESIGN, SETTING, AND PARTICIPANTS: This retrospective cohort study included all Medicare fee-for-service beneficiaries with AMI between January 1, 2018, and December 31, 2023, in the analysis. Data were analyzed from …

Strategic Resource Management In Pandemics: Integrating Capacity Planning With Non-Pharmaceutical Interventions For Covid-19, Ozlem Cosgun, Eyyub Kibis, Ali Dag, Burak Cankaya

Department of Information Management and Business Analytics Faculty Scholarship and Creative Works

The COVID-19 pandemic underscored the urgent need for integrated healthcare resource planning to manage patient surges and reduce mortality. This study presents a novel optimization-based framework that jointly considers healthcare capacity planning and non-pharmaceutical interventions (NPIs), including mask mandates, social distancing, and quarantining. The framework extends traditional compartmental models by distinguishing patient categories—such as hospitalized non-ventilator patients, ventilated patients, and ICU admissions—within a mixed-integer programming (MIP) structure that remains computationally tractable. Applied to the COVID-19 outbreak in New York City, the model optimizes the allocation of hospital beds and ventilators while minimizing deaths. Results show that combining high-effectiveness NPIs with …

Associations Between Sociodemographic Predictors And Age Of Referral For Autism Spectrum Disorder (Asd) Diagnosis Since The Beginning Of The Covid-19 Pandemic, Mallika Mathur, Ruosha Li, Sandra Mckay, Christine Markham, Deepali K Ernest, Shreela Sharma

Faculty, Staff and Student Publications

Purpose: Sociodemographic characteristics, such as race and ethnicity, are associated with delays in ASD diagnosis. However, limited literature has examined the characteristics associated with delayed diagnosis since the start of the COVID-19 pandemic. This study aimed to identify the individual and aggregate sociodemographic characteristics associated with the age at which a child receives a referral for a diagnosis (from March 2020 to May 2023) and evaluate the impacts of the pandemic on this association.

Methods: Using cross-sectional data obtained from patients' electronic health records and the U.S. Census Bureau, we examined associations using linear regressions (N = 507). A subgroup …

Partisan Differences In Risk-Taking In A Simulated Pandemic, Jan K. Woike, Sebastian Hafenbrädl, Patricia Kanngiesser, Ralph Hertwig

School of Psychology

Responses to COVID-19 in the United States were split along partisan political lines throughout the pandemic. People on the political left tended to take the medical threat more seriously and were more likely to adopt preventive health behaviors than those on the political right, resulting in clear differences in state-level policies and health consequences. Here, we examine the origins of these differences, investigating whether they are based on interindividual differences or in party dynamics. Two groups of participants (N=819), who had voted either for Donald Trump or Hillary Clinton in 2016, played the Transmission Game. Players made repeated decisions in …

Clinical Features, Laboratory Characteristics, And Outcomes Of Covid-19 Patients In A Tertiary Care Reference Hospital In Panama City, Panama. A Retrospective Observational Study, Santiago E. Hernandez Bojorge

USF Tampa Graduate Theses and Dissertations

Latin America experienced some of the world’s highest COVID-19 mortality rates, yet data on in-hospital outcomes and their social and geographic determinants remain limited. This dissertation investigated multilevel baseline factors associated with in-hospital mortality among adults with COVID-19 at Panama’s largest public tertiary hospital (Hospital Santo Tomás), integrating survival, mediation, and spatial-temporal modeling within a causal-inference framework.

A retrospective cohort of 1,526 RT-PCR–confirmed COVID-19 hospitalizations (May 2020–November 2021) was analyzed using multivariable Cox proportional-hazards, Fine–Gray competing-risk, mediation, and Bayesian spatial models. Directed acyclic graphs (DAGs) pre-specified causal relationships and minimally sufficient adjustment sets. DAG-guided models quantified total effects without conditioning …

Factors Associated With Telemedicine Use By Cardiologists For Medicare Beneficiaries In 2022 To 2023: An Observational Study, Samantha Harris, R J Waken, Fengxian Wang, Khavya C Avula, Rishi K Wadhera, Jose F Figueroa, E John Orav, Uchenna Ofoma, Karen E Joynt Maddox

2020-Current year OA Pubs

BACKGROUND: During the COVID-19 pandemic, the Centers for Medicare and Medicaid Services created a waiver to reimburse telemedicine services. It is important to understand factors that facilitate incorporation of telemedicine into ongoing cardiovascular practice.

METHODS: This was a retrospective cohort study of telemedicine and office visits delivered by cardiologists between January 1, 2022, and December 31, 2023, for Medicare beneficiaries. We calculated the adjusted incidence rate ratio (aIRR) of telemedicine visits, representing the proportion of a physician's visits delivered by telemedicine, to identify factors associated with telemedicine use.

RESULTS: There were 23 334 physicians in our cohort; they were predominantly …

Rural Georgia Hospital Covid-19 Virus Patient Outcomes, Susan P. Smith, Neeraj Dayama, Morgan E. House, Debra Flores, Sharon Hunt, April Dukes, Steven Gautney

Journal of the Georgia Public Health Association

Background: The Coronavirus disease 2019 (COVID-19) has led to over 1.2 million deaths in the United States. Given the staggering scale of the pandemic, rural hospitals faced heightened challenges due to limited resource availability and underlying patient characteristics.

Methods: In this context, we examined patient and hospital-related factors associated with inpatient mortality due to COVID-19. This study is a retrospective chart review of patient outcomes of patients who were hospitalized in a Southwest Georgia rural hospital with COVID-19 during the initial onset of the outbreak and over the following 23 months of the pandemic. Patient demographics, other characteristics, …

Partial 16srrna Gene Sequencing Of Legionella Pneumophila Isolated From Covid-19 Iraqi Patients, Rabab Chyad Al-Baderi, Ibtisam Habeb Al-Azawi

Al-Qadisiyah Medical Journal

Legionella pneumophila gram-negative, aerobic bacilli that do not form spores, are capsule-free, and possess the enzymes catalase and oxidase ,belong to genus legionella which single genus in legonellacea family  the genus legionella consist of 53 spices and 70 serogroup.  Legionella ubiquite and inhabits nature water such as rivers and  lacks  and artificial water also moist soil.  infection occur when human inhaled aerosol contained pathogen or aspiration .Person to person not transmitted  after inhaled bacteria invade alveolar macrophage and other cells such as monocytes by process know coiling phagocytosis. The current study aimed to detect Legionella pneumophila and  identification of DNA …

Computational Discovery Of Sars-Cov-2 Viral Entry Inhibitory Peptides From Androctonus Mauretanicus Scorpion Venom: Molecular Docking And Molecular Dynamics Simulations Targeting The Spike Protein, Reda Chahir, Salaheddine Redouane, Jacob Galan, Hicham Hboub, Lahoussaine Aserrar, Salma Chakir, Ahmed Salim Lahlou, Hinde Aassila, Rachid El Fatimy, Naoual Oukkache

School of Medicine Publications

Background and Objective: 

While vaccination remains central to controlling the COVID-19 pandemic, the emergence of SARS-CoV-2 variants with partial resistance to immune responses has highlighted the need for complementary therapeutic strategies. Among these, antiviral agents that inhibit viral entry mechanisms are of particular interest. Animal venoms, especially scorpion venoms, are a rich source of bioactive peptides with potential antiviral properties. This study aimed to evaluate peptides derived from the Moroccan scorpion Androctonus mauretanicus as inhibitors of SARS-CoV-2 spike glycoprotein, which mediates virus entry into host cells via ACE2 receptor binding.

Material and Methodology: 

Six peptides from the venom of the …

Reaching Learners Where They Are: Podcasting As A Scalable Tool For The National Physical Therapy Exam Preparation, Bhupinder Singh, Rudri Purohit, Emily Gerbehy, Derek Camilleri

Internet Journal of Allied Health Sciences and Practice

Purpose: The National Physical Therapy Examination (NPTE) is a pivotal requirement for PT licensure in the US. While conventional preparation methods such as textbooks, review courses, and standardized practice exams are effective, they often pose logistical and financial challenges. Method: The COVID-19 pandemic accelerated the adoption of asynchronous, on-demand educational tools. Among these, podcasting has emerged as a promising, mobile-friendly modality, yet its usage trends and educational value for NPTE preparation remain underexplored. The purpose of this study was to analyze multiyear podcast engagement data from a high-performing NPTE-focused podcast hosted on Buzzsprout, spanning January 2020 to March 2025. Engagement …

Muscular Fitness Levels Of U.S. Children And Adolescents, Daniel J. Mcdonough, Yong Gao, Lynda B. Ransdell, Haichun Sun

International Journal of Physical Activity and Health

Purpose: To describe muscular fitness (MF) levels and percentile benchmarks among U.S. children and adolescents aged 6–15 years old across sociodemographic, physiological, and behavioral subgroups. Methods: Data were from the 2012 NHANES National Youth Fitness Survey (NNYFS). Four strength tests consisting of the plank, knee extension, modified pull-up, and handgrip, were analyzed by age, sex, race/ethnicity, income, BMI category, cardiorespiratory fitness (CRF), and physical activity (PA) among 1,234 participants (51% male) using SAS SURVEY procedures. Results: Mean ± SEM scores were 69.6 ± 1.8 s (plank), 56.6 ± 4.2 lb (left) and 59.2 ± 4.3 lb (right) knee extension, 5.5 …