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The Emotions Of Uncertainty: Science, Politics, And The Social Dynamics Of Decision Making, Alisa N. Rogers

Sociology ETDs

This dissertation examines how social and emotional factors influence attitudes toward science and decision making regarding science-based policy recommendations during the COVID-19 pandemic. I examine boundary work practices among the public as they evaluate experts during the pandemic and the social sources of information people used to construct knowledge. Then I examine the social and emotional factors that participants indicated influenced their own attitude formation and decisions to act regarding public health recommendations during the pandemic. I find that emotions influence each element of the decision process: information gathering, information evaluation, attitude formation, and decisions to act. Affective commitment and …

Early Nintedanib Deployment In Covid-19 Interstitial Lung Disease (Endcov-I): Study Protocol Of A Randomised, Double-Blind, Placebo-Controlled Trial, Valeria Santibanez, Aditi Mathur, Jigna Zatakia, Nicole Ng, Michele Cohen, Emilia Bagiella, Stacey-Ann Brown, Ivan O Rosas, Nina M Patel, Amy Olson, Peide Li, Maria Padilla

Faculty, Staff and Students Publications

Introduction: In December 2019, the novel SARS-CoV-2 triggered a global pneumonia outbreak, leading to millions of deaths worldwide. A subset of survivors faces increased morbidity and mortality, particularly due to subacute lung injury evolving to chronic fibrosing interstitial lung disease. While nintedanib, a tyrosine-kinase inhibitor, shows promise in treating progressive fibrotic lung disease, limited randomised trial data exists for post-COVID-19-induced lung injury. We hypothesise that treatment with nintedanib may attenuate advancement to the fibrotic stages, offering a potential avenue for improving outcomes in this specific patient subset.

Methods and analysis: We describe the design of a multicentre, randomised, double-blind, placebo-controlled …

An Exploration Of The Relationship Between Age And Disposition In The Juvenile Court Data, Jaden Reign Deblois

Honors Program Theses and Projects

Struggles with depression are prominent among the population of incarcerated individuals. After COVID-19, the impacts of depression became more profound among incarcerated youth. For youth with previous diagnoses, the impacts of depression were more severe. To better understand the scope of the issue, this literature review examines how the field currently understands COVID-19’s impact on the depression of incarcerated youth. Findings suggest that factors such as isolation, physiological social stressors, and prior mental health diagnosis contribute to depression among incarcerated youth. Implications for mental health prevention and treatment for incarcerated youth will be discussed.

Characterizing Stroke Presenting To A Regional Referral Hospital Before And During The Covid-19 Pandemic In Uganda: A Retrospective Analysis, Christopher Burant, Shirley Moore, Martha Sajatovic

Faculty Scholarship

Introduction: Stroke, a leading cause of global morbidity and mortality, disproportionately impacts low and middle-income countries, particularly in sub-Saharan Africa (SSA) which reports the highest stroke burden. The COVID-19 pandemic further complicated this situation, emerging as a significant stroke risk factor. The pandemic also disrupted healthcare systems worldwide, affecting stroke management and care accessibility, and leading to deteriorated conditions in stroke patients upon hospital admission. In this pre/during COVID-19 pandemic analysis of acute stroke cases presenting to a Ugandan hospital, we investigated the relationship between stroke admissions, management and treatment outcomes. Methods: This was a retrospective medical record review in …

Actor–Partner Model Of Parenting And Co-Parenting Practices And Youth Resilience During The Covid-19 Pandemic, Olivia Aspiras, Jaimie O'Gara, Justine Radunzel

Faculty Publications

The present research examined parents' perspectives of co-parenting and supportive and hostile parenting as predictors of youth resilience during the COVID-19 pandemic. Participants were 47 mother/father dyads who had at least one K-12 child (Mage = 11.40, SD = 3.92). Mothers and fathers each completed an online survey that measured parenting, co-parenting, and youth resilience during the pandemic. Data were analyzed using the actor–partner interdependence model. Results revealed a positive relationship between mother supportiveness and perceived youth resilience; in contrast, increased father supportiveness was associated with lower perceived youth resilience. For both mothers and fathers, increases in their own hostility …

The Impact Of Covid-19 On Nurses' Feelings, Stress, Coping, And Motivation In Palestinian Treatment Centers Of Corona, † Wafaa Menawi, Shatha Mari, Ahmad Adel Hanani

An-Najah University Journal for Research - B (Humanities)

Background: Frontline nurses of COVID-19 found themselves in an unfamiliar new disease work environment, fighting to adapt and control the stress while working at covid-19 centers in Palestine. Aim: To investigate the impact of COVID-19 on nurses' feelings, stress, coping, and motivation in COVID-19 Palestinian treatment Centers. Method: A descriptive cross-sectional design was conducted between Mid of July to the end of October 2021 by recruiting a purposive sample of 390 nurses who worked at the Ministry of Health during COVID-19 pandemic treatment centers. The nurses filled out the COVID-19 Health Personnel Questionnaire with Cronbach's Alpha > 0.9. Results: Palestinian frontline …

Effective Strategies Used By Supply Chain Leaders To Mitigate Profitability Issues Created By The Covid-19 Pandemic, Sherri Janay Franklin

Walden Dissertations and Doctoral Studies

The COVID-19 pandemic has thrown the global supply chain into chaos, causing many companies to shut down. Supply chain leaders are concerned about global supply disruptions because they negatively impact profitability and daily life in society. Grounded in resource dependence theory, the purpose of this qualitative pragmatic inquiry is to explore the strategies that supply chain leaders implement to address the profitability issues triggered by the COVID-19 pandemic. The participants include five successful supply chain leaders selected from social media platforms, residing in different states across the United States. Data were collected through semi-structured interviews via Zoom and from online …

Emotional Intelligence And Effective Leadership In Times Of Global Crisis: A Mixed-Methods Study Of Managers At Multilateral Development Institutions During The Covid-19 Pandemic, Bukola Ogunyemi

Dissertations

Purpose: The purpose of this mixed-methods study was to identify and describe the perceptions of managers at multilateral development institutions regarding the impact of emotional intelligence methods in their approaches to leading during the COVID-19 pandemic. A secondary purpose was to examine how the experiences of leading during the COVID-19 crisis influenced managers' understanding, development, and application of emotional intelligence skills as part of their leadership practices.

Methodology: This study employed a convergent parallel mixed-methods design to examine the role of emotional intelligence in crisis leadership at multilateral development institutions during the COVID-19 pandemic. Using Goleman's emotional intelligence framework as …

The Impact Of Long Covid On Language Proficiency Across Different School Levels In Hong Kong, Shebe S. Xu, Yixun Li, Wanyi Li, Catherine M. Capio, Winnie W.Y. Tso, Derwin K.C. Chan

Health Sciences Faculty Publications

Long COVID, where symptoms persist after recovering from COVID-19, can affect cognitive functions like language. However, little is known about its impact on children’s language skills, especially across different school levels. This study investigated the impact of long COVID on language proficiency among 1244 children (Asian; 53.5% boys) from kindergartens (N = 408, Mage = 4.42 ± 1.26 years), primary schools (N = 547, Mage = 9.69 ± 1.96 years), and secondary schools (N = 289, Mage = 14.97 ± 1.85 years) in Hong Kong. Language proficiency was assessed using the Language Experience and Proficiency Questionnaire (LEAP-Q), which measured speaking, …

Ai Diagnostic Tool For Covid-19 Severity, Hunter Lau, Ryan Lang, Aidan Furuhashi

Bioengineering Senior Theses

With the advent of COVID-19 pandemic global, healthcare systems were challenged with resource constraints plaguing hospital environments around the world with consequences that presented weaknesses in our healthcare system. This demonstrated the importance of triage in unprecedented scenarios. This project presents an integrated AI-driven diagnostic tool to predict the severity of COVID-19 cases using length of stay as an analog. By using clinical data and radiographic chest images, this project integrates a XGBoost clinical data model with a Convolutional Neural Network (CNN) model utilizing chest CT images to create a comprehensive assessment of patient case severity through predicted length of …

Telehealth Or In-Person Hiv Care? Qualitative Study Findings On Decision-Making From People With Hiv And Hiv Care Providers In South Carolina During The Covid-19 Pandemic, Valerie Yelverton, Salome Joelle Gass, Daniel Amoatika, Christopher Cooke, Jan Ostermann, Nabil Natafgi, Nicole L. Hair Ph.D., Bankole Olatosi Ph.D., Otis L. Owens, Shan Qiao Ph.D., Xiaoming Li Ph.D., Caroline Derrick, Sharon Weissman, Helmut Albrecht

Faculty Publications

The COVID-19 pandemic disrupted HIV care services across the United States. Telehealth was rapidly implemented to ensure HIV care continuity. Despite the evidence of unequal telehealth uptake among some people with HIV (PWH), the decision-making processes to determine who received telehealth or in-person care are under-researched. This study assessed which decision criteria and processes determined which HIV care visit type was used by PWH and HIV care providers during the COVID-19 pandemic. Qualitative in-depth interviews with 18 PWH and 10 HIV care providers from South Carolina assessed PWHs’ and HIV care providers’ decision-making criteria and processes for telehealth HIV care …

Soluble Cd13 Is A Potential Mediator Of Neutrophil-Induced Thrombogenic Inflammation In Sars-Cov-2 Infection, Pei-Suen Tsou, Ramadan A. Ali, Chenyang Lu, Gautam Sule, Carmelo Carmona-Rivera, Serena Lucotti, Yuzo Ikari, Qi Wu, Phillip L. Campbell, Mikel Gurrea-Rubio, Kohei Maeda, Sharon E. Fox, William D. Brodie, Megan N. Mattichak, Caroline Foster, Ajay Tambralli, Srilakshmi Yalavarthi, M Asif Amin, Katarina Kmetova, Bruna Mazetto Fonseca, Emily Chong, Yu Zuo, Michael D. Maile, Luisa Imberti, Arnaldo Caruso, Francesca Caccuri, Virginia Quaresima, Alessandra Sottini, Douglas B. Kuhns, Et Al

School of Medicine Faculty Publications

The soluble variant of the ectopeptidase CD13 (sCD13), released from the cell surface by matrix metalloproteinase 14 (MMP14), is a potent pro-inflammatory mediator, displaying chemotactic, angiogenic, and arthritogenic properties through bradykinin receptor B1 (B1R). We revealed a link between sCD13 and amplified neutrophil-mediated inflammatory responses in SARS-CoV-2 infection. sCD13 was markedly elevated in patients with COVID-19 and correlated with disease severity and variants, ethnicity, inflammation markers, and neutrophil extracellular trap formation (NETosis). Neutrophils treated with sCD13 showed heightened NETosis and chemotaxis, which were inhibited by sCD13 receptor blockade. Meanwhile sCD13 did not induce platelet aggregation. Single-cell analysis of COVID-19 lungs …

Tutoring And Its Impact On Mitigating Covid-19 Reading Learning Loss In A Rural Title I School District For 3rd Grade Students, Julie Nicole Goodin

Student Theses and Dissertations

This mixed-methods study evaluated the impact of a tutoring program on third-grade students' reading achievement, focusing on rural Title I schools. The research used the Kellogg Logic Model to assess the program's short-term outcomes. It analyzed universal reading data for one hundred and three third-grade students and gathered the perspectives from nineteen stakeholders, including teachers, parents, and administrators. The researcher assessed the long-term outcomes by analyzing data on third-grade students' overall academic reading growth and by examining the stakeholders' perceptions of the program's effectiveness. The themes for the study from the participants included the benefits of tutoring, bus transportation, use …

Methylation Patterns Of The Nasal Epigenome Of Hospitalized Sars-Cov-2 Positive Patients Reveal Insights Into Molecular Mechanisms Of Covid-19., Benjamin L. Spector, Boryana Koseva, Rebecca Mclennan, Dithi Banerjee, Kamani Lankachandra, Todd Bradley, Rangaraj Selvarangan, Elin Grundberg

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has varied presentations from asymptomatic to death. Efforts to identify factors responsible for differential COVID-19 severity include but are not limited to genome wide association studies (GWAS) and transcriptomic analysis. More recently, variability in host epigenomic profiles have garnered attention, providing links to disease severity. However, whole epigenome analysis of the respiratory tract, the target tissue of SARS-CoV-2, remains ill-defined.

RESULTS: We interrogated the nasal methylome to identify pathophysiologic drivers in COVID-19 severity through whole genome bisulfite sequencing (WGBS) of nasal samples from COVID-19 positive individuals …

Factors Associated With Shock At Presentation In Kawasaki Disease Versus Multisystem Inflammatory Syndrome In Children Associated With Covid-19., Supriya S. Jain, Ashraf S. Harahsheh, Simon Lee, Geetha Raghuveer, Nagib Dahdah, Michael Khoury, Michael A. Portman, Melissa Wehrmann, Arash A. Sabati, Marianna Fabi, Deepika Thacker, Nilanjana Misra, Mark D. Hicar, Nadine F. Choueiter, Matthew D. Elias, Audrey Dionne, William B. Orr, Jacqueline R. Szmuszkovicz, Seda Selamet Tierney, Luis Martin Garrido-Garcia, Frederic Dallaire, Balasubramanian Sundaram, Deepa Prasad, Tyler H. Harris, Elizabeth Braunlin, Elisa Fernandez Cooke, Cedric Manlhiot, Pedrom Farid, Brian W. Mccrindle, International Kawasaki Disease Registry

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: While clinical overlap between Kawasaki disease (KD) and multisystem inflammatory syndrome in children (MIS-C) has been evident, information regarding those presenting with shock has been limited. We sought to determine associations with shock within and between diagnosis groups.

METHODS: The International KD Registry enrolled contemporaneous patients with either KD or MIS-C from 39 sites in 7 countries from January 1, 2020, to January 1, 2023. Demographics, clinical features and presentation, management, laboratory values, and outcomes were compared between the diagnosis and shock groups.

RESULTS: Shock at presentation was noted for 19 of 672 KD patients (2.8%) and 653 of …

Duty To Care And Job Turnover Intention In The Post-Pandemic Nursing Workforce, Cathleen A. Lopez

Nursing Theses and Dissertations

Natural and human-made disasters are increasing in number and intensity. In 2020, approximately 688.3 million people required assistance from disaster response personnel. During a disaster or pandemic, nurses must weigh their personal and/or family safety against the ethical code of caring for others. The purpose of this convergent mixed-methods study was to examine duty to care and job turnover intention of registered nurses working in patient-facing roles. A convergent mixed method design was used to address research questions by employing the Nash Duty to Care Scale (NDCS) and the Turnover Intent Scale (TIS-6). Open-ended survey questions were used to explore …

Developing A Pandemic-Related Mental Health Micro-Collection For An Academic Library, Dee Anna Phares

Faculty Articles, Papers, and Other Scholarship

Academic library patrons dealing with the impact of trauma, depression, anxiety, or addiction spawned or exacerbated by the COVID-19 pandemic require materials that address the unique conditions that have shaped mental health since late 2019. This paper demonstrates how one academic library endeavored to address patrons’ needs for mental health resources by developing a “Coping and COVID-19” micro-collection.

"When The Bills Keep On Coming:" The Experiences Of Seafood Processors During The Covid-19 Pandemic, Shannon Guillot-Wright, Laura Porterfield, Brenda Wilson, Lacy Davis

Faculty, Staff and Student Publications

Essential workers were at increased risk during the COVID-19 pandemic, including seafood processors who are often rendered invisible within the public sphere. To examine the health and safety concerns of seafood processors, many who are low income or im/migrant workers on H-2B visas, our team conducted qualitative research with 44 participants. We found that in addition to high occupational health hazards that existed before the pandemic, COVID-19 increased workers' financial risks, which put them in more dangerous health and safety positions, since they needed to work through physical and mental health illness. These financial risks can be seen through the …

Cytokine Storms In Covid-19, Hemophagocytic Lymphohistiocytosis, And Car-T Therapy, James P Long, Rishab Prakash, Paul Edelkamp, Mark Knafl, Anath C Lionel, Ranjit Nair, Sairah Ahmed, Paolo Strati, Luis E Malpica Castillo, Ajlan Al-Zaki, Kelly Chien, Dai Chihara, Jason Westin, Fareed Khawaja, Loretta J Nastoupil, Victor Mulanovich, Andrew Futreal, Scott E Woodman, Naval G Daver, Christopher R Flowers, Sattva Neelapu, Joanna-Grace Manzano, Swaminathan P Iyer

Faculty, Staff and Student Publications

Importance: Cytokine storm (CS) is a hyperinflammatory syndrome causing multiorgan dysfunction and high mortality, especially in patients with malignant hematologic neoplasms. Triggers include malignant neoplasm-associated hemophagocytic lymphohistiocytosis (MN-HLH), cytokine release syndrome from chimeric antigen receptor T-cell therapy (CAR-T CRS), and COVID-19, but the underlying mechanisms of inflammation and their impact on outcomes are poorly understood.

Objective: To delineate the inflammatory patterns characterizing different CS etiologies and their association with clinical outcomes.

Design, setting, and participants: This retrospective cohort study was conducted at the MD Anderson Cancer Center in Houston, Texas, between March 1, 2020, and November 20, 2022, using the …

Art In Public: Potential Public Pedagogy Post-Pandemic, Lyndall Adams, Nicola Kaye, Emma Jayakumar, Clive Barstow, Harrison See

Research outputs 2022 to 2026

This article speculates how art in public space might evolve in a COVID-19 world. We examine the complexity embedded within the realm of public space using two public art projects as case studies: an artwork produced as part of an artist residency inside the Parliament of Western Australia and a public artwork commission for a highway interchange at Wanneroo, Western Australia. Both projects are used as examples to speculate on how we might navigate the complexity and possibilities for art in public as a consequence of a refiguration of such public spaces resulting from COVID-19 prevention measures. This article postulates …

Analyzing Social Media Trends In Cosmeceuticals: Insights From Google Trends And Tiktok Analytics, E. Correia, Jenna Mandel, Stephanie R. Jackson Cullison

Department of Dermatology and Cutaneous Biology Faculty Papers

OBJECTIVE: Social media usage has surged, particularly since the COVID-19 pandemic. Dermatology invokes intense interest on social media, and cosmeceuticals are among the most trending topics, offering a unique space for dermatologists to share their expertise. By using tools like Google Trends and TikTok viewership, we aim to capture cosmeceutical trends to guide dermatologists' educational efforts.

METHODS: A Google Trends search from January 2004 to December 2023 was performed on retinol, bakuchiol, salicylic acid, glycolic acid, azelaic acid, hydroquinone, niacinamide, vitamin C serum, and hyaluronic acid. Trend lines were created for each term, and yearly percent differences in relative search …

Cultivation Of Global Competencies In The Post-Covid-19 Era: A Multinational Survey, Reiko Yamada, Rie Mori, Yumiko Sugitani, Takurya Kimura, Shihwei Sun

Journal of Comparative & International Higher Education

No abstract provided.

Insights Into Covid-19 Dynamics Via The Integration Of Subpopulations, Vaccinations, And Bayesian Calibration In A Semi-Enclosed Community Model Framework, Meghan Rowan Childs

Theses

From the beginning of the COVID-19 pandemic, universities have experienced unique challenges due to their multifaceted nature as a place of education, residence, and employment. Previous work has used mathematical models to explore varying approaches to combating COVID-19 and tailored these models to local contexts, such as hospitals. However, previous work has not broadly incorporated pharmaceutical mitigation strategies into university models. We address this gap in research by integrating subpopulations, vaccines, and COVID-19 variants into a semi-enclosed population model framework. We further improve the quantification of uncertainty in the model parameters by implementing a formal Bayesian model calibration, fusing real-world …

Systemic Inflammation Is Associated With Worse Outcomes From Sars-Cov-2 Infection But Not Neutralizing Antibody, Christopher W Farnsworth, Brittany Roemmich, John Prostko, Gerard Davis, Gillian Murtagh, Laurel Jackson, Christopher Jacobson, Nicolette Jeanblanc, Timothy Griffiths, Edwin Frias, David J Daghfal

2020-Current year OA Pubs

Systemic inflammation is associated with COVID-19 mortality rates, but the impact of inflammation on neutralizing antibodies to severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) and on outcomes is poorly understood. This study aimed to determine the association between neutralizing antibody responses, inflammation, and clinical outcomes in hospitalized patients with COVID-19. Two hundred and eight patients presenting to the ED with symptomatic SARS-CoV-2 were included. Neutralization was assessed using the architect angiotensin-converting enzyme-2 (ACE2) binding inhibition assay, and inflammation was assessed using C reactive protein (CRP) and interleukin 6 (IL-6). Medical records were examined for 30-day mortality and 10-day intubation. Correlation …

Single-Nucleus Transcriptional Profiling Of The Placenta Reveals The Syncytiotrophoblast Stress Response To Covid-19, Rachel A Keuls, Scott A Ochsner, Mary B O'Neill, Diana R O'Day, Akihiko Miyauchi, Kadeshia M Campbell, Natalie Lanners, Jeffery A Goldstein, Connor Yee, Neil J Mckenna, Ronald J Parchem, Jacqueline G Parchem

Faculty, Staff and Students Publications

Background: COVID-19 in pregnancy is associated with placental immune activation, inflammation, and vascular malperfusion, but its impact on syncytiotrophoblast biology and function is unclear.

Objective: This study aimed to determine the effects of maternal COVID-19 on placental syncytiotrophoblasts using single-nucleus transcriptional profiling and to compare placental stress responses in COVID-19 and preeclampsia.

Study design: For transcriptional characterization of syncytiotrophoblasts, we used the single-nucleus RNA sequencing platform, single-cell combinatorial indexing RNA sequencing (sci-RNA-seq3), to profile placental villi and fetal membranes from unvaccinated patients with symptomatic COVID-19 at birth (n = 4), gestational age-matched controls (n = 4), and a case of …

Current Burden Of Steatotic Liver Disease And Fibrosis Among Adults In The United States, 2017-2023, Donghee Kim, Pojsakorn Danpanichkul, Karn Wijarnpreecha, George Cholankeril, Rohit Loomba, Aijaz Ahmed

Faculty, Staff and Students Publications

Background/aims: Multi-society experts proposed the adoption of new terminology, metabolic dysfunctionassociated steatotic liver disease (MASLD) and steatotic liver disease (SLD). We studied the current prevalence of SLD and its subcategories in the US.

Methods: Using the recent National Health and Nutrition Examination Survey from 2017 to 2023, we analyzed data from 12,199 participants (≥18 years) who completed transient elastography. SLD and its subcategories, including MASLD, metabolic and alcohol-related liver disease (MetALD), and alcohol-related liver disease (ALD), were categorized according to consensus nomenclature.

Results: The age-adjusted prevalence of SLD (cut-off: 285 dB/m) was 35.0% (95% confidence interval [CI] 33.4-36.7). Within this …

The Burden Of Steatotic Liver Disease Before And During The Covid-19 Pandemic: Correspondence To Editorial On “Current Burden Of Steatotic Liver Disease And Fibrosis Among Adults In The United States, 2017–2023”, Donghee Kim, Pojsakorn Danpanichkul, Karn Wijarnpreecha, George Cholankeril, Rohit Loomba, Aijaz Ahmed

Faculty, Staff and Students Publications

No abstract provided.

Examining The Impact Of Feature Selection Techniques On Machine And Deep Learning Models For The Prediction Of Covid 19, Hafiza Zoya Mojahid, Jasni Mohamad Zain, Marina Yusoff, Abdul Basit, Abdul Kadir Jumaat, Mushtaq Ali

Malaysian Journal of Computing (MJoC)

Feature selection is a vital preprocessing step for identifying the most informative features in complex datasets, enhancing the efficiency and accuracy of machine learning models. Its applications extend across various domains, including big data analytics, finance, chemometrics, medical diagnostics, biological research, intrusion detection systems, and renewable energy solutions. In medical contexts, feature selection serves a dual purpose: it reduces dimensionality while simultaneously improving the comprehension of disease etiology. This study delves into key variable selection methods—specifically Recursive Feature Elimination (RFE), Principal Component Analysis (PCA) and Least Absolute Shrinkage and Selection Operator (LASSO). We evaluate the interaction of these methods with …

Factors Associated With Shock At Presentation In Kawasaki Disease Versus Multisystem Inflammatory Syndrome In Children Associated With Covid-19, Supriya S Jain, William B Orr, Et Al.

2020-Current year OA Pubs

BACKGROUND: While clinical overlap between Kawasaki disease (KD) and multisystem inflammatory syndrome in children (MIS-C) has been evident, information regarding those presenting with shock has been limited. We sought to determine associations with shock within and between diagnosis groups.

METHODS: The International KD Registry enrolled contemporaneous patients with either KD or MIS-C from 39 sites in 7 countries from January 1, 2020, to January 1, 2023. Demographics, clinical features and presentation, management, laboratory values, and outcomes were compared between the diagnosis and shock groups.

RESULTS: Shock at presentation was noted for 19 of 672 KD patients (2.8%) and 653 of …

Vaccination As A Protective Factor Against Hospitalization For Sars-Cov-2 Infections: An Observational Study Using Surveillance Data, Chandrayani Simanjorang, Kristin Mutiara Tarigan, Diva Anita Churiana Sudrajat, Rana Zahra Raniyah Wangsawinangun, Asy Syifa Anwari Zahra

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Death due to SARS-CoV-2 generally occurs in patients requiring hospital care (hospitalization). However, it is still unclear whether vaccination acts as a protective factor against hospitalization in SARS-CoV-2 patients in Indonesia. This study examines the association between vaccination and hospitalization among SARS-CoV-2 patients. It employs a quantitative, cross-sectional design using secondary data from SARS-CoV-2 surveillance records at the Jakarta Health Agency (January–August 2021). Findings show that patients who received the 1st vaccine dose had a 0.34 times lower risk of hospitalization compared to unvaccinated individuals (aPOR=0.34; 95% CI=0.31–0.38). Those who received the 2nd dose had an even lower risk (aPOR=0.16; …