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COVID-19

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Recovering From Covid-19 Building Closures: Guidance Document, David Krause, Cheri Marcham, John Springston, Alex Lebeau, Robert Rottersman, Timothy Froehlig, Bart Ashley Jan 2020

Recovering From Covid-19 Building Closures: Guidance Document, David Krause, Cheri Marcham, John Springston, Alex Lebeau, Robert Rottersman, Timothy Froehlig, Bart Ashley

Publications

While the country comes to terms with the inevitable impact that SARS-CoV-2, the virus that causes COVID-19, will have on our lives and communities, public health authorities remain focused on breaking the chain of transmission. Managing the risk has resulted in widespread closures of businesses, schools, universities, resorts, and other facilities deemed “non-essential.” Practically speaking, this means closing buildings and ceasing operations. For building owners and operators, this poses a significant challenge to protect their assets and to ensure they are ready to reoccupy once the pandemic subsides.


Cultured Meat Could Prevent The Next Pandemic, Jonathan Anomaly Jan 2020

Cultured Meat Could Prevent The Next Pandemic, Jonathan Anomaly

Animal Sentience

Wiebers & Feigin identify intensive agriculture and trade in exotic animals as the main sources of novel zoonotic viral infections. They recommend a transition away from meat. I would add that we would do well to invest in the mass production of cultured meat, derived from stem cells, as a radical alternative to animal agriculture.


The Immigrant Population Amid Covid-19 Pandemic Crisis: A Compiled Project For Nurs 518, Maureen S. Reyes Jan 2020

The Immigrant Population Amid Covid-19 Pandemic Crisis: A Compiled Project For Nurs 518, Maureen S. Reyes

Population Health

Immigrants has been part of the United States (US) historical society ever since this country has long been discovered. They say that this nation is built by immigrants. Some people would strongly disagree; but to be fair that is a reality. The American economy has long thrive and sustained, and has been strengthened by the contributions made by immigrants. Immigrants come from a variety of cultural and ethnic backgrounds; each with their own stories to tell and traditions to share.

The COVID-19 pandemic has made an impact on the socioeconomic and health care inequities of vulnerable and undeserved communities in …


Three Cases Of Covid-19 Pneumonia That Responded To Icosapent Ethyl Supportive Treatment, Winston Suh, Ivan Urits, Omar Viswanath, Alan D. Kaye, Haresh Patel, Wade Hall, Jonathan P. Eskander Jan 2020

Three Cases Of Covid-19 Pneumonia That Responded To Icosapent Ethyl Supportive Treatment, Winston Suh, Ivan Urits, Omar Viswanath, Alan D. Kaye, Haresh Patel, Wade Hall, Jonathan P. Eskander

Ellmer School of Nursing Faculty Publications

BACKGROUND Icosapent ethyl, a form of eicosapentaenoic acid with anti-inflammatory activity, has been approved as an adjunctive treatment with statins in patients with hypertriglyceridemia. Icosapent ethyl is currently undergoing clinical trials to determine its anti-inflammatory effects in patients with coronavirus disease 2019 (COVID-19). This report describes 3 intensive care unit (ICU) patients with moderate to severe COVID-19 pneumonia treated with icosapent ethyl as part of their supportive care who had favorable outcomes.

CASE REPORT Case 1 was a 75-year-old man with a past medical history of hyperlipidemia, hypertension, type 2 diabetes mellitus, obesity, and benign prostatic hyperplasia. Case 2 was …


An Insight Into The Epitope-Based Peptide Vaccine Design Strategy And Studies Against Covid-19, Murat Topuzoğullari, Tayfun Acar, Peli̇n Peli̇t Arayici, Burcu Uçar, Erennur Uğurel, Emrah Şefi̇k Abamor, Tüli̇n Arasoğlu, Di̇lek Balik, Serap Derman Jan 2020

An Insight Into The Epitope-Based Peptide Vaccine Design Strategy And Studies Against Covid-19, Murat Topuzoğullari, Tayfun Acar, Peli̇n Peli̇t Arayici, Burcu Uçar, Erennur Uğurel, Emrah Şefi̇k Abamor, Tüli̇n Arasoğlu, Di̇lek Balik, Serap Derman

Turkish Journal of Biology

SARS-CoV-2 is a new member of the coronavirus family and caused the pandemic of coronavirus disease 2019 (COVID-19) in 2020. It is crucial to design and produce an effective vaccine for the prevention of rapid transmission and possible deaths wcaused by the disease. Although intensive work and research are being carried out all over the world to develop a vaccine, an effective and approved formulation that can prevent the infection and limit the outbreak has not been announced yet. Among all types of vaccines, epitope-based peptide vaccines outshine with their low-cost production, easy modification in the structure, and safety. In …


Advanced Preparation Makes Research In Emergencies And Isolation Care Possible: The Case Of Novel Coronavirus Disease (Covid-19), David Brett-Major, Elizabeth R. Schnaubelt, Hannah M. Creager, Abigail Lowe, Theodore J. Cieslak, Jacob M. Dahlke, Daniel W. Johnson, Paul D. Fey, Keith F. Hansen, Angela L. Hewlett, Bruce G. Gordon, Andre C. Kalil, Ali S. Khan, Mark G. Kortepeter, Christopher J. Kratochvil, Luann Larson, Deborah A. Levy, James Linder, Sharon J. Medcalf, Mark E. Rupp, Michelle M. Schwedhelm, James N. Sullivan Md, Angela M. Vasa, Michael C. Wadman, Rachel E. Lookadoo, John-Martin J. Lowe, James V. Lawler, M. Jana Broadhurst Jan 2020

Advanced Preparation Makes Research In Emergencies And Isolation Care Possible: The Case Of Novel Coronavirus Disease (Covid-19), David Brett-Major, Elizabeth R. Schnaubelt, Hannah M. Creager, Abigail Lowe, Theodore J. Cieslak, Jacob M. Dahlke, Daniel W. Johnson, Paul D. Fey, Keith F. Hansen, Angela L. Hewlett, Bruce G. Gordon, Andre C. Kalil, Ali S. Khan, Mark G. Kortepeter, Christopher J. Kratochvil, Luann Larson, Deborah A. Levy, James Linder, Sharon J. Medcalf, Mark E. Rupp, Michelle M. Schwedhelm, James N. Sullivan Md, Angela M. Vasa, Michael C. Wadman, Rachel E. Lookadoo, John-Martin J. Lowe, James V. Lawler, M. Jana Broadhurst

Journal Articles: Epidemiology

The optimal time to initiate research on emergencies is before they occur. However, timely initiation of high-quality research may launch during an emergency under the right conditions. These include an appropriate context, clarity in scientific aims, preexisting resources, strong operational and research structures that are facile, and good governance. Here, Nebraskan rapid research efforts early during the 2020 coronavirus disease pandemic, while participating in the first use of U.S. federal quarantine in 50 years, are described from these aspects, as the global experience with this severe emerging infection grew apace. The experience has lessons in purpose, structure, function, and performance …


An Examination Of Covid-19 Statistical Modeling, Shane Vaughan Jan 2020

An Examination Of Covid-19 Statistical Modeling, Shane Vaughan

Williams Honors College, Honors Research Projects

The 2019 novel coronavirus, also known as COVID-19, is an infectious disease which was first reported in late 2019 and soon spread to become a global pandemic, prompting major action from world governments. Soon after, many institutions began attempts to analyze and predict the spread and severity of the disease via statistical modeling. Some information is not available for public consumption; however, a number of institutions have published the results of their analyses and some have made public repositories of the code used to build the models. This research paper attempts use these and other resources to examine the modeling …


Health Information Seeking Among General Public In India During Covid 19 Outbreak: Exploring Healthcare Practices, Information Needs, Preferred Information Sources And Problems, Nida Nafees, Daud Khan Jan 2020

Health Information Seeking Among General Public In India During Covid 19 Outbreak: Exploring Healthcare Practices, Information Needs, Preferred Information Sources And Problems, Nida Nafees, Daud Khan

Library Philosophy and Practice (e-journal)

Background: As of October 1, 2020, World Health Organization (WHO) reports that COVID-19 has spread in 216 countries or territories or areas which results into throwing billions of lives under lockdown as healthcare services struggle to cope. Therefore, timely access to healthcare information during COVID-19 crisis is mandatory to restrain its spread.

Objectives: To comprehend the information needs and seeking behaviour of general public during COVID-19 outbreak in India.

Methods: A national survey through an online questionnaire was conducted in India and 1310 respondents participated in the study through snowball sampling technique.

Results: The most decisive information needs of majority …


Law, Structural Racism, And The Covid-19 Pandemic, Ruqaiijah Yearby, Seema Mohapatra Jan 2020

Law, Structural Racism, And The Covid-19 Pandemic, Ruqaiijah Yearby, Seema Mohapatra

All Faculty Scholarship

Racial and ethnic minorities have always been the most impacted by pandemics because of: disparities in exposure to the virus; disparities in susceptibility to contracting the virus; and disparities in treatment. This article explains how structural racism, the ways in which laws are used to advantage the majority and disadvantage racial and ethnic minorities, has caused these disparities. Specifically, this article focuses on how employment, housing, health care, and COVID-19 relief laws have been manipulated to disadvantage racial and ethnic minorities, making minorities more susceptible to COVID-19 infection and death. This article uses Blumenshine’s 2008 framework to outline how structural …


Covid-19 Risk Among Temporary Protected Status Beneficiaries, Diana Estefania Estrada Alamo Jan 2020

Covid-19 Risk Among Temporary Protected Status Beneficiaries, Diana Estefania Estrada Alamo

Public Health Theses

The current federal response of the United States to the COVID-19 pandemic has created conditions and resulted in unintended consequences that may be disproportionately increasing the risk of COVID-19 infection and sequelae for immigrant populations. This investigative thesis explores whether states with a greater percentage of Temporary Protected Status beneficiaries experience more COVID-19 related deaths as compared to the rest of the United States. Using a multiple linear regression model for statistical analysis, covariates under consideration include the number of COVID-19 confirmed cases, tests performed, hospitalizations reported, as well as the population density of each state and the proportion of …


Covid-19: Prevention And Control Measures In Community, Hati̇ce Rahmet Güner, İmran Hasanoğlu, Fi̇rdevs Aktaş Jan 2020

Covid-19: Prevention And Control Measures In Community, Hati̇ce Rahmet Güner, İmran Hasanoğlu, Fi̇rdevs Aktaş

Turkish Journal of Medical Sciences

On January 30, 2020, the WHO declared the COVID-19 outbreak a public health emergency of international concern and, in March 2020, began to characterize it as a pandemic in order to emphasize the gravity of the situation and urge all countries to take action in detecting infection and preventing spread. Unfortunately, there is no medication that has been approved by the FDA, gone through controlled studies and demonstrated an effect on the virus for this global pandemic. Although there are cures for illnesses and developments made by leaps and bounds in our day, the strongest and most effective weapon that …


How Well Does Societal Mobility Restriction Help Control The Covid-19 Pandemic? Evidence From Real-Time Evaluation, Juhwan Oh, Hwa-Young Lee, Khuong Quynh Long, Jeffrey F. Markuns, Chris Bullen, Osvaldo Enrique Artaza Barrios, Seung-Sik Hwang, Young Sahng Seo, Judith Mccool, S. Patrick Kachur, Chang-Chung Chan, Soonman Kwon, Naoki Kondo, Hoang Van Minh, J. Robin Moon, Mikael Rostila, Ole F. Norheim, Myoungsoon You, Mellissa Withers, Mu Lil, Eun-Jeung Lee, Caroline Benski, Soo Kyung Park, Eun-Woo Nam, Katie Gottschalk, Matthew M. Kavanagh, Jong-Koo Lee, Martin Mckee, S. V. Subramanian, Lawrence O. Gostin Jan 2020

How Well Does Societal Mobility Restriction Help Control The Covid-19 Pandemic? Evidence From Real-Time Evaluation, Juhwan Oh, Hwa-Young Lee, Khuong Quynh Long, Jeffrey F. Markuns, Chris Bullen, Osvaldo Enrique Artaza Barrios, Seung-Sik Hwang, Young Sahng Seo, Judith Mccool, S. Patrick Kachur, Chang-Chung Chan, Soonman Kwon, Naoki Kondo, Hoang Van Minh, J. Robin Moon, Mikael Rostila, Ole F. Norheim, Myoungsoon You, Mellissa Withers, Mu Lil, Eun-Jeung Lee, Caroline Benski, Soo Kyung Park, Eun-Woo Nam, Katie Gottschalk, Matthew M. Kavanagh, Jong-Koo Lee, Martin Mckee, S. V. Subramanian, Lawrence O. Gostin

Georgetown Law Faculty Publications and Other Works

One of the most widely implemented policy response to the novel coronavirus (SARS-CoV-2) pandemic has been the imposition of restrictions on mobility (1). These restrictions have included both incentives, encouraging working from home, supported by a wide range of online activities such as meetings, lessons, and shopping, and sanctions, such as stay at home orders, restrictions on travel, and closure of shops, offices, and public transport (2-5). The measures constitute a major component of efforts to control the COVID-19 pandemic. Compared to previous epidemic responses, they are unprecedented in both scale and scope (6).

The rationale underpinning these public health …


Unsafe At Any Campus: Don't Let Colleges Become The Next Cruise Ships, Nursing Homes, And Food Processing Plants, Peter H. Huang, Debra S. Austin Jan 2020

Unsafe At Any Campus: Don't Let Colleges Become The Next Cruise Ships, Nursing Homes, And Food Processing Plants, Peter H. Huang, Debra S. Austin

Publications

The decision to educate our students via in-person or online learning environments while COVID-19 is unrestrained is a false choice, when the clear path to achieve our chief objective safely, the education of our students, can be done online. Our decision-making should be guided by the overriding principle that people matter more than money. We recognize that lost tuition revenue if students delay or defer education is an institutional concern, but we posit that many students and parents would prefer a safer online alternative to riskier in-person options, especially as we get closer to fall, and American death tolls rise. …


Mindfulness And Engagement In Covid-19 Preventive Behavior, Ilana Haliwa, Jerin Lee, Natalie J. Shook Jan 2020

Mindfulness And Engagement In Covid-19 Preventive Behavior, Ilana Haliwa, Jerin Lee, Natalie J. Shook

Faculty & Staff Scholarship

The novel coronavirus disease 2019 (COVID-19) pandemic represents a significant risk to population health. Health organizations worldwide have recommended numerous preventive health behaviors to slow the spread of COVID-19. Yet, considerable variability exists in individual-level adherence to these recommendations. Mindfulness has been associated with greater engagement in health promotive behavior (e.g., physical activity, healthy eating), and may serve as an individual difference factor that encourages adherence. However, no study to date has examined the extent to which mindfulness is associated with preventive health behaviors during a global pandemic. The purpose of the present study was to assess the relations between …


Be A Hero Too, Samantha S. Rohe, Sophie Cemaj Jan 2020

Be A Hero Too, Samantha S. Rohe, Sophie Cemaj

Books: Pediatrics

This children's book explains COVID-19 and how to decrease the incidence of transmissions.


Public Health Law Tools: A Brief Guide, Kristen Underhill Jan 2020

Public Health Law Tools: A Brief Guide, Kristen Underhill

Faculty Scholarship

The COVID-19 pandemic offers a threat with few precedents in modern times and tests the tools of modern surveillance and public health law. The goal of this chapter is to provide a brief overview of the types of measures that state and federal governments can invoke to treat and prevent the spread of infectious disease. The following sections will provide an orientation to domestic public health law followed by the types of measures available to state and federal public health authorities.

Although this chapter does not consider international institutions, treaties, or norms that affect public health, these are also essential …


Linked Fate: Justice And The Criminal Legal System During The Covid-19 Pandemic, Susan P. Sturm, Faiz Pirani, Hyun Kim, Natalie Behr, Zachary D. Hardwick Jan 2020

Linked Fate: Justice And The Criminal Legal System During The Covid-19 Pandemic, Susan P. Sturm, Faiz Pirani, Hyun Kim, Natalie Behr, Zachary D. Hardwick

Faculty Scholarship

The concept of “linked fate” has taken on new meaning in the face of the COVID-19 pandemic. People all over the world – from every walk of life, spanning class, race, gender, and nationality – face a potentially deadly threat requiring cooperation and sacrifice. The plight of the most vulnerable among us affects the capacity of the larger community to cope with, recover, and learn from COVID-19’s devastating impact. COVID-19 makes visible and urgent the need to embrace our linked fate, “develop a sense of commonality and shared circumstances,” and unstick dysfunctional and inequitable political and legal systems.

Nowhere is …


Unf Covid-19 Education Program, Center For Professional Development And Training Jan 2020

Unf Covid-19 Education Program, Center For Professional Development And Training

UNF COVID-19 Response

No abstract provided.


Chest Ct Features Of The Novel Coronavirus Disease (Covid-19), Furkan Ufuk, Recep Savaş Jan 2020

Chest Ct Features Of The Novel Coronavirus Disease (Covid-19), Furkan Ufuk, Recep Savaş

Turkish Journal of Medical Sciences

A new type of coronavirus (2019-nCoV) is rapidly spreading worldwide and causes pneumonia, respiratory distress, thromboembolic events, and death. Chest computed tomography (CT) plays an essential role in the diagnosis of viral pneumonia, monitoring disease progression, determination of disease severity, and evaluating therapeutic efficacy. Chest CT can show important clues of 2019-nCoV disease (also known as COVID-19) in patients with an appropriate clinic. Prompt diagnosis of COVID-19 is essential to prevent disease transmission and provides close clinical observation of patients with clinically severe disease. Therefore, radiologists and clinicians should be familiar with the CT imaging findings of COVID-19 pneumonia. Herein, …


The Effects Of Blood Group Types On The Risk Of Covid-19 Infection And Its Clinical Outcome, Hakan Göker, Eli̇fcan Aladağ Karakulak, Haluk Demi̇roğlu, Çağlayan Merve Ayaz Ceylan, Yahya Büyükaşik, Ahmet Çağkan İnkaya, Salih Aksu, Ni̇lgün Sayinalp, İbrahi̇m Celaletti̇n Haznedaroğlu, Ömrüm Uzun, Murat Akova, Osman İlhami̇ Özcebe, Serhat Ünal Jan 2020

The Effects Of Blood Group Types On The Risk Of Covid-19 Infection And Its Clinical Outcome, Hakan Göker, Eli̇fcan Aladağ Karakulak, Haluk Demi̇roğlu, Çağlayan Merve Ayaz Ceylan, Yahya Büyükaşik, Ahmet Çağkan İnkaya, Salih Aksu, Ni̇lgün Sayinalp, İbrahi̇m Celaletti̇n Haznedaroğlu, Ömrüm Uzun, Murat Akova, Osman İlhami̇ Özcebe, Serhat Ünal

Turkish Journal of Medical Sciences

Background/aim: COVID-19 (Coronavirus disease of 2019) is an infectious disease outbreak later on declared as a pandemic, caused by the SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2). It spreads very rapidly and can result in severe acute respiratory failure. The clinical studies have shown that advanced age and chronic diseases increase the risk of infection. However, influence of the blood groups on COVID-19 infection and its outcome remains to be confirmed. The aim of this study is to investigate whether there exists a relationship between the blood groups of the patients and risk of SARS-CoV-2 infection and the clinical outcomes in …


The Factors Predicting Pneumonia In Covid-19 Patients: Preliminary Results From Auniversity Hospital In Turkey, Hasan Selçuk Özger, Pinar Aysert Yildiz, Ümmügülsüm Gaygisiz, Asi̇ye Uğraş Di̇kmen, Zehra Demi̇rbaş Gülmez, Mehmet Yildiz, Esi̇n Şenol, Kenan Hizel, Özlem Güzel Tunçcan, Kayhan Çağlar, Gülendam Bozdayi, Nurdan Köktürk, Tansu Ulukavak Çi̇ftçi̇, Şahender Gülbi̇n Aygencel Bikmaz, Melda Türkoğlu Jan 2020

The Factors Predicting Pneumonia In Covid-19 Patients: Preliminary Results From Auniversity Hospital In Turkey, Hasan Selçuk Özger, Pinar Aysert Yildiz, Ümmügülsüm Gaygisiz, Asi̇ye Uğraş Di̇kmen, Zehra Demi̇rbaş Gülmez, Mehmet Yildiz, Esi̇n Şenol, Kenan Hizel, Özlem Güzel Tunçcan, Kayhan Çağlar, Gülendam Bozdayi, Nurdan Köktürk, Tansu Ulukavak Çi̇ftçi̇, Şahender Gülbi̇n Aygencel Bikmaz, Melda Türkoğlu

Turkish Journal of Medical Sciences

Background/aim: Pneumonia is the most serious clinical presentation of COVID-19. This study aimed to determine the demographic, clinical, and laboratory findings that can properly predict COVID-19 pneumonia. Materials and methods: This study was conducted in the Gazi University hospital. All hospitalized patients with confirmed and suspected SARS-CoV-2 infection between 16 March 2020 and 30 April 2020 were analyzed retrospectively. COVID-19 patients were separated into two groups, pneumonia and nonpneumonia, and then compared to determine predicting factors for COVID-19 pneumonia. Variables that had a P-value of less than 0.20 and were not correlated with each other were included in the logistic …


A Single Center Cohort Of 40 Severe Covid-19 Patients Who Were Treated Withconvalescent Plasma, Ali̇i̇hsan Gemi̇ci̇, Hülya Bi̇lgen, Cem Erdoğan, Abdullah Kansu, Oktay Olmuşçeli̇k, Hüseyi̇n Saffet Beköz, Rumeysa Çakmak, Ali̇ Mert, Ömür Gökmen Sevi̇ndi̇k Jan 2020

A Single Center Cohort Of 40 Severe Covid-19 Patients Who Were Treated Withconvalescent Plasma, Ali̇i̇hsan Gemi̇ci̇, Hülya Bi̇lgen, Cem Erdoğan, Abdullah Kansu, Oktay Olmuşçeli̇k, Hüseyi̇n Saffet Beköz, Rumeysa Çakmak, Ali̇ Mert, Ömür Gökmen Sevi̇ndi̇k

Turkish Journal of Medical Sciences

Background/aim: A SARS-Cov2 infection which was first arised from Wuhan in December 2019 and named as COVID-19. Still there lacks either a specific treatment or a vaccine to treat COVID-19. Convalescent plasma (CP) was previously used successfully to treat SARS-CoV-1 and MERS infections. Health authority in Turkey has published a guideline to integrate this promising option in the treatment process of patients who are prone to high risk of developing severe COVID 19. Materials and Methods: Forty consecutive patients who had received CP at our center were included in the study. Demographics, COVID-19 specific parameters, biomarkers to detect the severity …


Covid-19 And Dermatology, Ülker Gül Jan 2020

Covid-19 And Dermatology, Ülker Gül

Turkish Journal of Medical Sciences

Background/aim: Sars-CoV-2 virus infection (COVID-19) was observed in China in the last months of 2019. In the period following, this infection spread all over the world. In March 2020 the World Health Organization announced the existence of a pandemic. The aim of this manuscript is to investigate skin diseases associated with COVID-19 under three main headings: skin problems related to personal protective equipment and personal hygiene measures, skin findings observed in SARS-CoV-2 virus infections, and skin findings due to COVID-19 treatment agents. Materials and methods: In PubMed, Google Scholar databases, skin lesions related to personal protective equipment and personal hygiene …


Covid-19-Related Anxiety In People Living With Hiv: An Online Cross-Sectional Study, Özlem Kuman Tunçel, Hüsnü Pullukçu, Hüseyi̇n Aytaç Erdem, Behi̇ce Kurtaran, Seli̇n Ece Taşbakan, Meltem Taşbakan Jan 2020

Covid-19-Related Anxiety In People Living With Hiv: An Online Cross-Sectional Study, Özlem Kuman Tunçel, Hüsnü Pullukçu, Hüseyi̇n Aytaç Erdem, Behi̇ce Kurtaran, Seli̇n Ece Taşbakan, Meltem Taşbakan

Turkish Journal of Medical Sciences

Background/aim: The emergence of the coronavirus disease 2019 (COVID-19) outbreak has had an enormous emotional impact on some vulnerable groups, such as people living with human immunodeficiency virus (HIV) (PLHIV). This study was planned with the aim of assessing the anxiety levels of PLHIV and the sources of their anxiety. Materials and methods: A web-based questionnaire was sent to PLHIV using the virtual snowball sampling method. The questionnaire included questions about sociodemographic status, information about HIV infection, and the Beck Anxiety Inventory (BAI). Additionally, some opinions of the participants about COVID-19 were asked. Results: A total of 307 respondents, with …


Covid-19 Experience Of The Major Pandemic Response Center In The Capital: Results Ofthe Pandemic's First Month In Turkey, Hati̇ce Rahmet Güner, İmran Hasanoğlu, Bi̇rcan Kayaaslan, Adalet Aypak, Ayşe Kaya Kalem, Fatma Eser, Burcu Özdemi̇r, Eli̇f Muki̇me Saricaoğlu, Müge Ayhan, Yeşi̇m Aybar Bi̇li̇r, Işil Özkoçak Turan, Deni̇z Erdem, Nevzat Mehmet Mutlu, Turan Buzğan, Bedi̇a Di̇nç Jan 2020

Covid-19 Experience Of The Major Pandemic Response Center In The Capital: Results Ofthe Pandemic's First Month In Turkey, Hati̇ce Rahmet Güner, İmran Hasanoğlu, Bi̇rcan Kayaaslan, Adalet Aypak, Ayşe Kaya Kalem, Fatma Eser, Burcu Özdemi̇r, Eli̇f Muki̇me Saricaoğlu, Müge Ayhan, Yeşi̇m Aybar Bi̇li̇r, Işil Özkoçak Turan, Deni̇z Erdem, Nevzat Mehmet Mutlu, Turan Buzğan, Bedi̇a Di̇nç

Turkish Journal of Medical Sciences

Background/aim: The aim of this study is to evaluate the epidemiological and clinical characteristics and parameters that determined the clinical course and prognosis of the COVID-19 patients admitted to Ankara City Hospital during the first month of the pandemic in Turkey. Materials and methods: SARS-CoV-2 PCR positive patients who were hospitalized between March 10 and April 10, 2020 were included. Results: Among 222 patients, mean age was higher in severe acute respiratory illness (SARI)/critical disease group (P < 0.001). Median time from illness onset to admission and presence of comorbidity, especially coronary artery disease and chronic obstructive pulmonary disease, were significantly higher in the SARI/critical disease group (P < 0.05). Cough and fever were the most common symptoms, while anosmia and loss of taste were observed in 8.6% and 7.7% patients, respectively. The mortality rate was 5.4%. A high neutrophil/lymphocyte ratio; low lymphocyte, monocyte, and platelet count; elevated liver enzymes; low GFR; and high levels of muscle enzymes, ferritin, and IL-6 on admission were found to be associated with SARI/critical disease (P < 0.05). Bilateral ground-glass opacity and patchy infiltration were more frequently seen in the SARI/critical disease group (P < 0.001). Patients older than 65 years had an 8-fold increased risk for development of SARI/critical disease. Conclusion: This cohort study regarding COVID-19 cases in Turkey reveals that older age, presence of comorbidity, bilateral infiltration on CT, high neutrophil/lymphocyte ratio, low monocyte and platelet count, elevated liver enzymes, low GFR, high levels of muscle enzymes, and high levels of ferritin and IL-6 on admission are predictors of SARI and severe disease.


Protective Measures For Covid-19 For Healthcare Providers And Laboratory Personnel, Canan Ağalar, Derya Öztürk Engi̇n Jan 2020

Protective Measures For Covid-19 For Healthcare Providers And Laboratory Personnel, Canan Ağalar, Derya Öztürk Engi̇n

Turkish Journal of Medical Sciences

In the COVID-19 pandemic, which affects the whole world, healthcare professionals (HCP) are at high risk of transmission due to their direct contact with patients with COVID-19. Therefore, how to ensure the triage of the patient with acute respiratory symptoms should be determined in advance, the contact distance should be arranged to be at least 2 m, COVID-19 suspect or diagnosed patient should be instructed to wear a surgical mask. During the care of these patients, HCP should wear their personal protective equipment (PPE) in accordance with the procedure and should not neglect hand hygiene. The samples of the patient …


Understanding Dynamics Of Pandemics, Levent Akin, Mustafa Gökhan Gözel Jan 2020

Understanding Dynamics Of Pandemics, Levent Akin, Mustafa Gökhan Gözel

Turkish Journal of Medical Sciences

Along the centuries, novel strain of virus such as influenza produces pandemics which increase illness, death and disruption in the countries. Spanish flu in 1918, Asian flu in 1957, Hong Kong flu in 1968 and swine flu in 2009 were known pandemic which had various characteristics in terms of morbidity and mortality. A current pandemic is caused by novel corona virus originated from China. COVID-19 pandemic is very similar to Spanish, Hong Kong, Asian and swine influenza pandemics in terms of spreading to world by the mobilized people. Burden of pandemic is considered in terms of disease transmissibility and the …


Sars-Cov-2 Epidemiology And Control, Different Scenarios For Turkey, Eskild Petersen, Ayşe Deni̇z Gökengi̇n Jan 2020

Sars-Cov-2 Epidemiology And Control, Different Scenarios For Turkey, Eskild Petersen, Ayşe Deni̇z Gökengi̇n

Turkish Journal of Medical Sciences

Background/aim: Coronavirus Infectious Disease 2019 (COVID-19) is now a pandemic spreading in most countries including Turkey. Materials and methods: The current knowledge of COVID-19 and the virus causing it, SARS-CoV-2, was reviewed. The epidemiology and control in different countries was compared and the differences discussed. Results: The population attack rates and case fatality rates vary from country to country with Lombardy in northern Italy reporting an attack rate in the general population of 0.37% compared to 0.004% in Hong Kong. The differences are caused by different testing strategies and reporting systems. Conclusion: Turkey is early in the outbreak. Different control …


Coronaviruses And Sars-Cov-2, Mustafa Hasöksüz, Selçuk Kiliç, Fahri̇ye Saraç Jan 2020

Coronaviruses And Sars-Cov-2, Mustafa Hasöksüz, Selçuk Kiliç, Fahri̇ye Saraç

Turkish Journal of Medical Sciences

Coronaviruses (CoVs) cause a broad spectrum of diseases in domestic and wild animals, poultry, and rodents, ranging from mild to severe enteric, respiratory, and systemic disease, and also cause the common cold or pneumonia in humans. Seven coronavirus species are known to cause human infection, 4 of which, HCoV 229E, HCoV NL63, HCoV HKU1 and HCoV OC43, typically cause cold symptoms in immunocompetent individuals. The others namely SARS-CoV (severe acute respiratory syndrome coronavirus), MERS-CoV (Middle East respiratory syndrome coronavirus) were zoonotic in origin and cause severe respiratory illness and fatalities. On 31 December 2019, the existence of patients with pneumonia …


Epidemiology Of Covid-19, Cemal Bulut, Yasuyuki̇ Kato Jan 2020

Epidemiology Of Covid-19, Cemal Bulut, Yasuyuki̇ Kato

Turkish Journal of Medical Sciences

It seems that coronaviruses take an important place in the 21th century history. Five of seven human coronavirus was isolated in this century. Unfortunately, last three of them entered our life with a fear of outbreak, pandemic or death. Last human coronavirus which emerged world from Wuhan China, SARS CoV-2 and its clinical expression, Coronavirus disease (COVID-19) recently taken a significant place in our daily practice. Initial reports showed that, its origin was bats. It transmitted human to human by droplet and contact routes, but some doubt about airborne, fecal or intrauterine transmission also should be removed. Its R0 value …