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COVID-19

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Baricitinib In The Treatment Of A Critical Patient With Covid-19 Pneumonia: A Case Report, Nishant Patel, Dylan Goldsmith, Forest W. Arnold Jul 2021

Baricitinib In The Treatment Of A Critical Patient With Covid-19 Pneumonia: A Case Report, Nishant Patel, Dylan Goldsmith, Forest W. Arnold

The University of Louisville Journal of Respiratory Infections

A 72-year-old male presented to the emergency department with a chief complaint of diarrhea after having tested positive for COVID-19 two days prior. He initially had minimal respiratory complaints, but was eventually transferred to the intensive care unit for acute hypoxic respiratory failure. In addition to dexamethasone, remdesivir, and antibiotics, the patient was treated with baricitinib, a Janus kinase inhibitor that was recently granted emergency use authorization by the Food and Drug Administration for treatment of hospitalized patients with COVID-19. He had an extensive and complicated hospital course and had to be placed on mechanical ventilation, ultimately undergoing tracheostomy. After …


2021-07-10_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services Jul 2021

2021-07-10_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated twice a week on Tuesdays and Fridays.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, …


County Youth Athletics Response To Covid-19 Pandemic, Elise Schaller Jul 2021

County Youth Athletics Response To Covid-19 Pandemic, Elise Schaller

Dissertations

Problem: To ensure safe participation in youth athletics and prevent COVID-19 transmission during the COVID-19 pandemic, St. Louis County Department of Public Health (DPH) implemented Youth Sports Guidelines on October 14, 2020. This project aimed to identify level of adherence to precautions listed in the guidelines at six county public high school athletic events.

Methods: An observational descriptive study design was used to monitor guideline adherence at high school athletic events. Two observers tallied violations by participants and spectators to Youth Sports Guidelines at St. Louis County public high school athletic events. Six high-frequency contact (basketball and wrestling) events …


Impact Of Social Isolation In Hiv-Positive Individuals During A Pandemic, Corina Jane Bakoylis Jul 2021

Impact Of Social Isolation In Hiv-Positive Individuals During A Pandemic, Corina Jane Bakoylis

Dissertations

Problem: The global pandemic of COVID-19 caused concern for immunocompromised individuals. The purpose of this quality improvement initiative was to assess the impact of social isolation on feelings of loneliness, depression, and social isolation experiences in HIV-positive individuals residing in a long-term care facility.

Methods: A mixed-method convergent design with a purposeful sample of HIV-positive adult residents residing in a long-term care facility was utilized. An evaluation of loneliness using the University of California Los Angeles (UCLA) Loneliness Scale (Version 3) and depression using the Patient Health Questionnaire-8 (PHQ-8) were completed. Personal experiences were also assessed with five predetermined open-ended …


Mental Health Concerns Of Frontline Registered Nurses Associated With The Covid-19 Pandemic, Julie Ingle Jul 2021

Mental Health Concerns Of Frontline Registered Nurses Associated With The Covid-19 Pandemic, Julie Ingle

Dissertations

Problem

COVID-19 caused local healthcare facilities to admit patients with COVID-19 at increasing rates, critically overloading healthcare system resources. Caregiver-related stress associated with the COVID-19 pandemic placed frontline registered nurses (RNs) at risk for mental health consequences (Havlioglu & Demir, 2020; Shechter et al.,2020).

Methods

This quality improvement project used a descriptive design to administer a collection of validated instruments assessing anxiety, depression, posttraumatic stress disorder (PTSD), and demographics. A purposive sample of RNs were recruited from the COVID-19 units in a local hospital, and the survey was distributed via email.

Results

During the implementation period (April 4, 2021-May 15, …


Youth Sports In A Pandemic Age, Robert Bohnert Jul 2021

Youth Sports In A Pandemic Age, Robert Bohnert

Dissertations

Abstract

Problem: Youth sporting events is a public health concern as infected youth with coronavirus disease 2019 may unknowingly spread the virus, as many show little to no symptoms (Zimmerman & Nigel, 2020). This project aimed to identify level of adherence to posted Youth Sports Guidelines, which were designed to mitigate the spread of virus at youth sporting events.

Methods: An observational descriptive design was utilized. Two observers tallied guideline violations by participants and spectators at six high-contact (basketball) and six low-contact (swimming) public high school youth sporting events.

Results: A total of 726 youth sport participants and 139 …


Mathematical Modeling, Analysis, And Simulation Of The Covid-19 Pandemic With Behavioral Patterns And Group Mixing, Comfort Ohajunwa, Padmanabhan Seshaiyer Jul 2021

Mathematical Modeling, Analysis, And Simulation Of The Covid-19 Pandemic With Behavioral Patterns And Group Mixing, Comfort Ohajunwa, Padmanabhan Seshaiyer

Spora: A Journal of Biomathematics

Due to the rise of COVID-19 cases, many mathematical models have been developed to study the disease dynamics of the virus. However, despite its role in the spread of COVID-19, many SEIR models neglect to account for human behavior. In this project, we develop a novel mathematical modeling framework for studying the impact of mixing patterns and social behavior on the spread of COVID-19. Specifically, we consider two groups, one exhibiting normal behavior who do not reduce their contacts and another exhibiting altered behavior who reduce their contacts by practicing non-pharmaceutical interventions such as social distancing and self-isolation. The dynamics …


2021-07-06_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services Jul 2021

2021-07-06_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated twice a week on Tuesdays and Fridays.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, …


Are Covid-19 Models Blind To The Social Determinants Of Health? A Systematic Review Protocol, Ava John-Baptiste, Marc S. Moulin, Shehzad Ali Jul 2021

Are Covid-19 Models Blind To The Social Determinants Of Health? A Systematic Review Protocol, Ava John-Baptiste, Marc S. Moulin, Shehzad Ali

Epidemiology and Biostatistics Publications

Introduction Infectious disease models are important tools to inform public health policy decisions. These models are primarily based on an average population approach and often ignore the role of social determinants in predicting the course of a pandemic and the impact of policy interventions. Ignoring social determinants in models may cause or exacerbate inequalities. This limitation has not been previously explored in the context of the current pandemic, where COVID-19 has been found to disproportionately affect marginalised racial, ethnic and socioeconomic groups. Therefore, our primary goal is to identify the extent to which COVID-19 models incorporate the social determinants of …


Functioning Of Health Care During The Covid-19 Pandemic – Review Of Literature, Józef Haczyński, Agnieszka Trojniak, Krzysztof Jarowicz, Dawid Skaza Jul 2021

Functioning Of Health Care During The Covid-19 Pandemic – Review Of Literature, Józef Haczyński, Agnieszka Trojniak, Krzysztof Jarowicz, Dawid Skaza

European Management Studies

Purpose: A review of the literature on reorganization of the health care system in selected medical specializations during the COVID-19 pandemic. Design/methodology/approach: A review and analysis of available scientific literature from ScienceDirect, Google Scholar, PubMed and other scientific sources, and data analysis using Microsoft Excel. Articles were found using specific keywords, then they were assessed in detail against the criteria set by the authors. Findings: The COVID-19 pandemic caused many organizational changes in health care. As a result of activities limiting the spread of COVID-19 in medical facilities, the following were observed: increased use of telemedicine to contact medical staff, …


The Role Of (Dis)Information In Society During The Covid-19 Pandemic, Zuzanna Czudy, Milena Matuszczak, Marta Donderska, Józef Haczyński Jul 2021

The Role Of (Dis)Information In Society During The Covid-19 Pandemic, Zuzanna Czudy, Milena Matuszczak, Marta Donderska, Józef Haczyński

European Management Studies

Purpose: Demonstrating the harmfulness of disinformation and summarizing the COVID-19 false information to which recipients are most often exposed. Confrontation of the most popular myths about SARS-CoV-2 with the results of Evidence-Based Medicine (EBM). Design/methodology/approach: A review of original papers and reviews of myths about COVID-19. Findings: The COVID-19 pandemic has challenged the public with information overload related to SARSCoV- 2. Some of this information may be false and potentially harmful. The rapid spread of information reaching a wide audience is also a threat. Research limitations/implications: The subject of COVID-19 is still unknown and is under constant research, there are …


Persistent Dyspnea, Declined Moderate To Vigorous Physical Activity, Functional Status, And Quality Of Life During The Post-Acute Phase Of Covid-19 Infection: A Pilot Case Control Study., Hussain Aslan Mph. Ed., Msc., Corey Tomczak Phd, Darcy Marciniuk Md, Scotty Butcher Phd Jul 2021

Persistent Dyspnea, Declined Moderate To Vigorous Physical Activity, Functional Status, And Quality Of Life During The Post-Acute Phase Of Covid-19 Infection: A Pilot Case Control Study., Hussain Aslan Mph. Ed., Msc., Corey Tomczak Phd, Darcy Marciniuk Md, Scotty Butcher Phd

Journal for Sports Neuroscience

Abstract

Purpose: The purpose of this study was to explore the multifaceted impacts of post-acute phase of COVID-19 infection on the sense of dyspnea, select intensities of physical activity, functional, and psychological variables among survivors compared to age matched healthy participants and their implications for rehabilitation programs in this population.

Methods: Seventy-eight (male, female age 30-70 yrs.) participants (39 COVID-infected, CI and 39 age-matched healthy controls, HC). Four questionnaires were used to assess the variables in this study: dyspnea scale of the Modified Medical Research Council (mMRC), International Physical Activity Questionnaire (IPAQ), Functional Status Questionnaire (FSQ), and the RAND-36 measure …


Covid-19 Pandemic Leadership A Case For Return To Platonic Values, Richard Runyon, Daryl Watkins Jul 2021

Covid-19 Pandemic Leadership A Case For Return To Platonic Values, Richard Runyon, Daryl Watkins

Publications

In western education, Plato is often cited as a foundational thinker for education of leaders. 2,395 years later, many leaders in governments of the world are struggling to address the COVID-19 global pandemic. The 2019–2021 global pandemic has provided academics with a wonderful opportunity to evaluate government leadership at many levels. All the different forms of governance as well as theoretical economic systems are being tested in real-time. Success can be measured on a government’s ability to reduce both deaths and spread of the COVID-19 virus among their citizens. This article will discuss these concepts focused on successful government leadership.


Capturing Quarantine:Student Pandemic Experience Journal, Ann Fernandez Jul 2021

Capturing Quarantine:Student Pandemic Experience Journal, Ann Fernandez

Public History Journals

Journal entries submitted by the Public History 2021 summer session class at Columbia College Chicago reflecting on aspects of the global pandemic from the student perspective.


Capturing Quarantine: Student Pandemic Experience Journal, Sofiya Vozyakova Jul 2021

Capturing Quarantine: Student Pandemic Experience Journal, Sofiya Vozyakova

Public History Journals

Journal entries submitted by the Public History 2021 summer session class at Columbia College Chicago reflecting on aspects of the global pandemic from the student perspective commenting on their personal pandemic timeline and the other is an essay about what each student learned so far from the pandemic.


Rural Community Pharmacies’ Preparedness For And Responses To Covid-19, Delesha M. Carpenter, Tessa Hastings, Salisa Westrick, Meagen Rosenthal Jul 2021

Rural Community Pharmacies’ Preparedness For And Responses To Covid-19, Delesha M. Carpenter, Tessa Hastings, Salisa Westrick, Meagen Rosenthal

Faculty and Student Publications

Background: Few studies have documented rural community pharmacy disaster preparedness. Objectives: To: (1) describe rural community pharmacies’ preparedness for and responses to COVID-19 and (2) examine whether responses vary by level of pharmacy rurality. Methods: A convenience sample of rural community pharmacists completed an online survey (62% response rate) that assessed: (a) demographic characteristics; (b) COVID-19 information source use; (c) interest in COVID-19 testing; (d) infection control procedures; (e) disaster preparedness training, and (f) medication supply impacts. Descriptive statistics were calculated and differences by pharmacy rurality were explored. Results: Pharmacists used the CDC (87%), state health departments (77%), and state …


Estimating Parameters Of A Seird Model Applied To Sars-Cov-2 Infections In Germany Based On The Particle Swarm Optimization Method, Evandro A. Nakajima, Antonio A. Ignacio, Denise Lange, Erika Izumi Jul 2021

Estimating Parameters Of A Seird Model Applied To Sars-Cov-2 Infections In Germany Based On The Particle Swarm Optimization Method, Evandro A. Nakajima, Antonio A. Ignacio, Denise Lange, Erika Izumi

Applied Mathematics & Information Sciences

The present paper describes a particle swarm optimization (PSO) method used to estimate parameters of a Susceptible- Exposed-Infected-Recovered-Dead (SEIRD) model applied to predict SARS-CoV-2 transmission in Germany, based on data from February 15th to April 25th, 2020, considering that the lockdown in the country started on March 23rd. The model estimated patients’ mortality (4.92%) and recovery rates (95.08%), virus incubation (8.54 days), infection periods (18.65 days), as well as the basic virus reproduction number before (R0 = 11.60) and after (R0 = 0.39) lockdown. The predicted values were accurate until the 70th day. The performances achieved by the model were …


Experiences And Coping Strategies During The Covid-19 Pandemic Among Fishers And Farmers In The Island Province Of Guimaras, Philippines, Gay Margarett A. Gange, Louie Marie T. Eluriaga, Alice Joan G. Ferrer Jul 2021

Experiences And Coping Strategies During The Covid-19 Pandemic Among Fishers And Farmers In The Island Province Of Guimaras, Philippines, Gay Margarett A. Gange, Louie Marie T. Eluriaga, Alice Joan G. Ferrer

Journal of Economics, Management and Agricultural Development

This study describes the experiences and coping strategies related with the COVID-19 threat and the community quarantine policy by the fishers and farmers in the island province of Guimaras. Both food producers faced marketrelated problems such as low demand, low prices of catch and produce, and logistical problems. While the in-kind support (e.g., food provisions) received and adaptive measures (e.g., continued with fishing or adjusted harvest schedule; use of social media or delivery services in marketing) allowed them to get by during the pandemic, there is a need to develop more resilient farming and fishing households. Short-term support can be …


Why New Diseases Keep Popping Up, Alan L. Gillen, Jason Conrad Jul 2021

Why New Diseases Keep Popping Up, Alan L. Gillen, Jason Conrad

Faculty Publications and Presentations

New and reemerging diseases are terrifying and concerning problems. Not only do they carry a financial and emotional toll, but they account for significant numbers of death. Emerging diseases are usually zoonotic and highly virulent in nature. These are pathogenic and parasitic diseases of high consequence and impact. Why would a good Creator allow these new diseases? Why do new diseases keep popping up? Mutation and displacement of original types of microbes account for many new diseases; however, the answer is more complex than just these two factors. Zoonoses are the most common type of infection, specifically from viral pathogens, …


Characteristics Of Patients Presenting With Covid-19 From Balochistan Province And Lessons Learnt, Abida Munir Badini, Aurangzeb Badini, Naeem M. Mengal, Kashmira Nanji Jul 2021

Characteristics Of Patients Presenting With Covid-19 From Balochistan Province And Lessons Learnt, Abida Munir Badini, Aurangzeb Badini, Naeem M. Mengal, Kashmira Nanji

Department of Family Medicine

Objective: With the spread of COVID-19 in Pakistan, Balochistan province with its unique problems of lowest literacy rates in the country, limited resources and a flail health care system is reporting an increasing number of cases of COVID-19. This study discusses the epidemiological and clinical characteristics of COVID-19 patients from the Balochistan province.
Study design: Situation report Place and Duration of Study: The study was conducted in Balochistan province of Pakistan. The completion date for the study was April 30, 2020.
Methodology: The data was retrieved from the daily situation report from the Health Department, Government of Balochistan. Descriptive statistics …


The Conundrum Of Low Covid-19 Mortality Burden In Sub-Saharan Africa: Myth Or Reality?, Janica Adams, Mary J. Mackenzie, Adeladza Kofi Amegah, Alex Ezeh, Muktar A. Gadanya, Akinyinka Omigbodun, Ahmed Sarki, Paul Thistle, Abdhalah K. Ziraba, Saverio Stranges, Michael Silverman Jul 2021

The Conundrum Of Low Covid-19 Mortality Burden In Sub-Saharan Africa: Myth Or Reality?, Janica Adams, Mary J. Mackenzie, Adeladza Kofi Amegah, Alex Ezeh, Muktar A. Gadanya, Akinyinka Omigbodun, Ahmed Sarki, Paul Thistle, Abdhalah K. Ziraba, Saverio Stranges, Michael Silverman

School of Nursing & Midwifery, East Africa

The burden of coronavirus disease (COVID-19) in sub-Saharan Africa (SSA) has been substantially lower compared to other regions of the world. Extensive morbidity and mortality were not observed among countries in SSA during the first wave of the COVID-19 pandemic. To explain this phenomenon, several hypotheses have been formulated, including the low median age of the population in most SSA countries, lack of long-term care facilities, cross-protection from other local coronaviruses, insufficient testing and reporting resulting in an undercounting of COVID-related deaths, genetic risk factors, or the benefit of early lockdowns that were extensive in many SSA countries. Early lockdowns …


School Of Nursing Newsletter Summer 2021, Southern Adventist University Jul 2021

School Of Nursing Newsletter Summer 2021, Southern Adventist University

Southern Nursing - School of Nursing Newsletter

The Summer 2021 issue of the newsletter features information on the new manikans in the Simulation and Skills Labs, COVID-19 task force, and a recently awarded grant.


Understanding The 1918-1920 Cultural Narrative Of The Spanish Flu As Told Through The New York Times And The Wall Street Journal, Gertrude Misornu Ofori-Parku Jul 2021

Understanding The 1918-1920 Cultural Narrative Of The Spanish Flu As Told Through The New York Times And The Wall Street Journal, Gertrude Misornu Ofori-Parku

Master's Theses (2009 -)

Global pandemics have become one of the major health crises that happen to society from time to time. Past occurrences, including disasters and pandemics, are events that we learn from and draw upon to better understand current happenings. One way by which we build and understand historical trends and events, including pandemics, is through press coverage of those events. One significant pandemic in history was the 1918 Spanish Flu pandemic. This thesis explores the cultural narrative about the Spanish Flu as told through The New York Times and The Wall Street Journal between 1918 and 1920. Through the constant comparison …


Changes In Air-Quality In Milwaukee, Wi Due The Covid-19 Lockdown, Nathan Hay Jul 2021

Changes In Air-Quality In Milwaukee, Wi Due The Covid-19 Lockdown, Nathan Hay

Master's Theses (2009 -)

Shortly after COVID-19 started spreading across the country, Wisconsin instituted their shutdown on March 23rd, 2020. With large swaths of the population forced to stay at home, this presented a unique case study to evaluate the effects of reduced traffic volumes on vehicle related emissions. To do so, this study measured air quality on a 40-mile route within Milwaukee County on Wednesdays and Saturdays from 4 to 6 PM from the beginning of April until the end of August. Mobile sensors – a Sniffer 4D and micro aethalometer – were attached to a car and collected particulate matter (1.0-10 μm), …


Mental Disorders Among Health Care Workers At The Early Phase Of Covid-19 Pandemic In Kenya; Findings Of An Online Descriptive Survey, Edith Kamaru Kwobah, Ann Mwangi, Kirtika Patel, Thomas Mwogi, Robert Kiptoo, Lukoye Atwoli Jul 2021

Mental Disorders Among Health Care Workers At The Early Phase Of Covid-19 Pandemic In Kenya; Findings Of An Online Descriptive Survey, Edith Kamaru Kwobah, Ann Mwangi, Kirtika Patel, Thomas Mwogi, Robert Kiptoo, Lukoye Atwoli

Internal Medicine, East Africa

Background: Healthcare workers responding to the Corona Virus Pandemic (COVID-19) are at risk of mental illness. Data is scanty on the burden of mental disorders among Kenyan healthcare workers responding to the pandemic that can inform mental health and psychosocial support. The purpose of this study was to establish the frequency and associated factors of worry, generalized anxiety disorder, depression, posttraumatic stress disorder and poor quality of sleep among Kenyan health care workers at the beginning of COVID-19 pandemic.

Methods: We conducted an online survey among 1,259 health care workers in Kenya. A researcher developed social demographic questionnaire and several …


Covid-19 And Mental Well-Being Of Nurses In A Tertiary Facility In Kenya, Sayed Karar, Jasmit Shah, Zohray Talib Jul 2021

Covid-19 And Mental Well-Being Of Nurses In A Tertiary Facility In Kenya, Sayed Karar, Jasmit Shah, Zohray Talib

Internal Medicine, East Africa

Background: The 2019 coronavirus disease (COVID-19) epidemic is a global health emergency which has been shown to pose a great challenge to mental health, well-being and resilience of healthcare workers, especially nurses. Little is known on the impact of COVID-19 among nurses in sub-Saharan Africa.

Methods: A cross sectional study was carried out between August and November 2020 among nurses recruited from the Aga Khan University Hospital, Nairobi. The survey questionnaire consisted of six components- demographic and work title characteristics, information regarding care of COVID-19 patients, symptoms of depression, anxiety, insomnia, distress and burnout, measured using standardized questionnaires. Multivariable logistic …


Assessment Of Concerns And Health-Seeking Behaviours Related To Covid-19 Infection, Elizebeth Rani. V, Sudha Arumugam, Yashodha G Jul 2021

Assessment Of Concerns And Health-Seeking Behaviours Related To Covid-19 Infection, Elizebeth Rani. V, Sudha Arumugam, Yashodha G

Manipal Journal of Nursing and Health Sciences

Assessment of concerns and health-seeking behaviours related to COVID-19 infection

Elizebeth Rani V 1* R Sudha 2 , Yashodha G 3

1. Reader, VHS-MA Chidambaram College of Nursing, Chennai, Tamil Nadu, India

2. Principal, VHS-MA Chidambaram College of Nursing, Chennai, Tamil Nadu, India

3. Lecturer, VHS-MA Chidambaram College of Nursing, Chennai, Tamil Nadu, India

*Corresponding author

Elizebeth Rani. V, Reader, VHS-MA Chidambaram College of Nursing, Chennai, Tamil Nadu, India

E-mail: [email protected]

Short title: Elizebeth et al. Health-seeking behaviours related to COVID-19.

How to cite this article: Elizebeth Rani V, Sudha R, & Yashodha G (2021). Assessment of …


Vulnerability To And Protection Against Covid-19 Fear, Threat, And Worry, Marsha Kim Huh Jul 2021

Vulnerability To And Protection Against Covid-19 Fear, Threat, And Worry, Marsha Kim Huh

Graduate Theses and Dissertations

Drawing from a sample of 10,368 adults living in the U.S., the current study examines the role of social and psychological resources in lowering COVID-related fear, threat, and worry, controlling for a number of social vulnerabilities (e.g. gender, race/ethnicity, and presence of children). The impact of social location, particularly in regards to race, and how one accesses and/or utilizes social and psychological resources is also examined through disaggregated regression models. Results demonstrate that some social and psychological resources impact COVID-specific distress (fear/threat/worry), but depending on the resource, relationships vary in direction and significance. The strength of social ties and mastery …


Global Impact Of Covid-19 On Stroke Care, Raul G. Nogueira, Mohamad Abdalkader, Muhammad M. Qureshi, Michael Frankel, Ossama Y. Mansour, Hiroshi Yamagami, Zhongming Qiu, Mehdi Farhoudi, James E. Siegler, Ameer E. Hassan Jul 2021

Global Impact Of Covid-19 On Stroke Care, Raul G. Nogueira, Mohamad Abdalkader, Muhammad M. Qureshi, Michael Frankel, Ossama Y. Mansour, Hiroshi Yamagami, Zhongming Qiu, Mehdi Farhoudi, James E. Siegler, Ameer E. Hassan

School of Medicine Publications

Background

The COVID-19 pandemic led to profound changes in the organization of health care systems worldwide.

Aims

We sought to measure the global impact of the COVID-19 pandemic on the volumes for mechanical thrombectomy, stroke, and intracranial hemorrhage hospitalizations over a three-month period at the height of the pandemic (1 March–31 May 2020) compared with two control three-month periods (immediately preceding and one year prior).

Methods

Retrospective, observational, international study, across 6 continents, 40 countries, and 187 comprehensive stroke centers. The diagnoses were identified by their ICD-10 codes and/or classifications in stroke databases at participating centers.

Results

The hospitalization volumes …


Implications Of Helminth Immunomodulation On Covid-19 Co-Infections, Nathalie Chacon, Leonor Chacin-Bonilla, Italo M. Cesar Jul 2021

Implications Of Helminth Immunomodulation On Covid-19 Co-Infections, Nathalie Chacon, Leonor Chacin-Bonilla, Italo M. Cesar

School of Medicine Publications

Coronavirus disease 2019 (COVID-19) and helminths infections can be in a synergistic epidemic in developing and suburban areas of industrialized countries. The coinfected hosts will derive a parasite-specific Th2 innate and adaptive immune response with CD4+ T cells, eosinophils, interleukin-4, interleukin-5, and interleukin-10. In the early stages of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection, virus-specific Th1 cytotoxic CD8+ T cell, interleukin-6, interferon-γ, and interleukin-27 by lung are keys in controlling viral replication in the lung epithelial cells and limiting the pathology to other organs, like the intestine. CD4+ and CD8+ T cells are associated with protective immunity …