Digital Commons Network^™

Single-Cell Multi-Omics Integration For Unpaired Data By A Siamese Network With Graph-Based Contrastive Loss, Chaozhong Liu, Linhua Wang, Zhandong Liu

Faculty, Staff and Students Publications

BACKGROUND: Single-cell omics technology is rapidly developing to measure the epigenome, genome, and transcriptome across a range of cell types. However, it is still challenging to integrate omics data from different modalities. Here, we propose a variation of the Siamese neural network framework called MinNet, which is trained to integrate multi-omics data on the single-cell resolution by using graph-based contrastive loss.

RESULTS: By training the model and testing it on several benchmark datasets, we showed its accuracy and generalizability in integrating scRNA-seq with scATAC-seq, and scRNA-seq with epitope data. Further evaluation demonstrated our model's unique ability to remove the batch …

2023-01-03_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus/stats.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. COVID case and testing data will be posted once a week on Tuesdays.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) …

Three Essays On The U.S. Beef Supply Chain: Production, Marketing, And Price Dynamics, Erdal Erol

Theses and Dissertations--Agricultural Economics

This dissertation contains three essays on select economic components of the U.S. beef industry. The first and second essays concentrate on the different economic problems in beef cattle production. The third essay evaluates the price dynamics and the impact of COVID-19 along the beef supply chain.

The first essay explores the economics of culling decisions in cow-calf operations in the U.S. with a novel application of a dynamic mathematical programming model. The results provide an optimal culling strategy under the base model and a range of optimal strategies that vary with respect to different components such as fertility probabilities, market …

For The Good Of The People: An Interpretive Analysis Of Chinese Volunteerism In The Critical Matter Of Care At The Start Of The Pandemic, Fan Li, Chunyun Gu, Yanqun Hu, Roxanne Vandermause, Anne F. Fish, Zehui Zhou, Xiaodan Yuan, Qianqian Zhou, Junya Zhu, Qingqing Lou

Nursing Faculty Works

Purpose: China employed a unique volunteerism system where health care providers outside of Hubei Province, the epicentre, travelled to reverse the devastation wrought by coronavirus disease 2019 (COVID-19) at its global onset. The aim is to study the unique circumstances of Chinese volunteerism in the context of continuing pandemic threats, specifically exploring the experiences of 20 Chinese nurse and physician volunteers fighting COVID-19 during the outbreak. Methods: Interviews were done through video calling. Results: Using content analysis with a hermeneutic perspective, emerging patterns showed the ways in which China’s particular manifestation of volunteerism teaches us how to engage global threats …

Lipid Alternations In The Plasma Of Covid-19 Patients With Various Clinical Presentations., Xiao Liang, Xin Qi, Jin Yang, Xiaorui Wang, Hongyu Qin, Fang Hu, Han Bai, Yixin Li, Chengsheng Zhang, Bingyin Shi

Faculty Research 2023

BACKGROUND: COVID-19 is a highly infectious respiratory disease that can manifest in various clinical presentations. Although many studies have reported the lipidomic signature of COVID-19, the molecular changes in asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected individuals remain elusive.

METHODS: This study combined a comprehensive lipidomic analysis of 220 plasma samples from 166 subjects: 62 healthy controls, 16 asymptomatic infections, and 88 COVID-19 patients. We quantified 732 lipids separately in this cohort. We performed a difference analysis, validated with machine learning models, and also performed GO and KEGG pathway enrichment analysis using differential lipids from different control groups.

RESULTS: …

Researching Covid To Enhance Recovery (Recover) Adult Study Protocol: Rationale, Objectives, And Design, Leora I Horwitz, Tanayott Thaweethai, Shari B Brosnahan, Mine S Cicek, Megan L Fitzgerald, Jason D Goldman, Rachel Hess, S L Hodder, Vanessa L Jacoby, Michael R Jordan, Jerry A Krishnan, Adeyinka O Laiyemo, Torri D Metz, Lauren Nichols, Rachel E Patzer, Anisha Sekar, Nora G Singer, Lauren E Stiles, Barbara S Taylor, Shifa Ahmed, Heather A Algren, Khamal Anglin, Lisa Aponte-Soto, Hassan Ashktorab, Ingrid V Bassett, Brahmchetna Bedi, Nahid Bhadelia, Christian Bime, Marie-Abele C Bind, Lora J Black, Andra L Blomkalns, Hassan Brim, Mario Castro, James Chan, Alexander W Charney, Benjamin K Chen, Li Qing Chen, Peter Chen, David Chestek, Lori B Chibnik, Dominic C Chow, Helen Y Chu, Rebecca G Clifton, Shelby Collins, Maged M Costantine, Sushma K Cribbs, Steven G Deeks, John D Dickinson, Sarah E Donohue, Matthew S Durstenfeld, Ivette F Emery, Kristine M Erlandson, Julio C Facelli, Rachael Farah-Abraham, Aloke V Finn, Melinda S Fischer, Valerie J Flaherman, Judes Fleurimont, Vivian Fonseca, Emily J Gallagher, Jennifer C Gander, Maria Laura Gennaro, Kelly S Gibson, Minjoung Go, Steven N Goodman, Joey P Granger, Frank L Greenway, John W Hafner, Jenny E Han, Michelle S Harkins, Kristine S P Hauser, James R Heath, Carla R Hernandez, On Ho, Matthew K Hoffman, Susan E Hoover, Carol R Horowitz, Harvey Hsu, Priscilla Y Hsue, Brenna L Hughes, Prasanna Jagannathan, Judith A James, Janice John, Sarah Jolley, S E Judd, Joy J Juskowich, Diane G Kanjilal, Elizabeth W Karlson, Stuart D Katz, J Daniel Kelly, Sara W Kelly, Arthur Y Kim, John P Kirwan, Kenneth S Knox, Andre Kumar, Michelle F Lamendola-Essel, Margaret Lanca, Joyce K Lee-Lannotti, R Craig Lefebvre, Bruce D Levy, Janet Y Lin, Brian P Logarbo, Jennifer K Logue, Michele T Longo, Carlos A Luciano, Karen Lutrick, Shahdi K Malakooti, Gail Mallett, Gabrielle Maranga, Jai G Marathe, Vincent C Marconi, Gailen D Marshall, Christopher F Martin, Jeffrey N Martin, Heidi T May, Grace A Mccomsey, Dylan Mcdonald, Hector Mendez-Figueroa, Lucio Miele, Murray A Mittleman, Sindhu Mohandas, Christian Mouchati, Janet M Mullington, Girish N Nadkarni, Erica R Nahin, Robert B Neuman, Lisa T Newman, Amber Nguyen, Janko Z Nikolich, Igho Ofotokun, Princess U Ogbogu, Anna Palatnik, Kristy T S Palomares, Tanyalak Parimon, Samuel Parry, Sairam Parthasarathy, Thomas F Patterson, Ann Pearman, Michael J Peluso, Priscilla Pemu, Christian M Pettker, Beth A Plunkett, Kristen Pogreba-Brown, Athena Poppas, J Zachary Porterfield, John G Quigley, Davin K Quinn, Hengameh Raissy, Candida J Rebello, Uma M Reddy, Rebecca Reece, Harrison T Reeder, Franz P Rischard, Johana M Rosas, Clifford J Rosen, Nadine G Rouphael, Dwight J Rouse, Adam M Ruff, Christina Saint Jean, Grecio J Sandoval, Jorge L Santana, Shannon M Schlater, Frank C Sciurba, Caitlin Selvaggi, Sudha Seshadri, Howard D Sesso, Dimpy P Shah, Eyal Shemesh, Zaki A Sherif, Daniel J Shinnick, Hyagriv N Simhan, Upinder Singh, Amber Sowles, Vignesh Subbian, Jun Sun, Mehul S Suthar, Larissa J Teunis, John M Thorp, Amberly Ticotsky, Alan T N Tita, Robin Tragus, Katherine R Tuttle, Alfredo E Urdaneta, P J Utz, Timothy M Vanwagoner, Andrew Vasey, Suzanne D Vernon, Crystal Vidal, Tiffany Walker, Honorine D Ward, David E Warren, Ryan M Weeks, Steven J Weiner, Jordan C Weyer, Jennifer L Wheeler, Sidney W Whiteheart, Zanthia Wiley, Natasha J Williams, Juan P Wisnivesky, John C Wood, Lynn M Yee, Natalie M Young, Sokratis N Zisis, Andrea S Foulkes

Pediatrics Research and Scholarship

IMPORTANCE: SARS-CoV-2 infection can result in ongoing, relapsing, or new symptoms or other health effects after the acute phase of infection; termed post-acute sequelae of SARS-CoV-2 infection (PASC), or long COVID. The characteristics, prevalence, trajectory and mechanisms of PASC are ill-defined. The objectives of the Researching COVID to Enhance Recovery (RECOVER) Multi-site Observational Study of PASC in Adults (RECOVER-Adult) are to: (1) characterize PASC prevalence; (2) characterize the symptoms, organ dysfunction, natural history, and distinct phenotypes of PASC; (3) identify demographic, social and clinical risk factors for PASC onset and recovery; and (4) define the biological mechanisms underlying PASC pathogenesis. …

When Privacy Proclivity Meet Covid-19: No Longer Concerns Of Today’S M-Commerce Users?, James L. Thomas, Jianping Coco Huang, Brent J. Cunningham, Jihye Lee, Le Wu

Atlantic Marketing Journal

This is continuous research of our previous publication (Thomas et al., 2021). A new two by two study (Before and After COVID 19) X (China and the US culture) was designed to test the moderated mediation effect of the COVID pandemic on M-commerce user’s privacy proclivity, trust, and M-commerce intention! A new sample was collected from two countries in different time periods (Before and after COVID pandemic) to investigate whether M-commerce users’ concern about privacy proclivity has changed after COVID-19. Built on top of our 2021 publication, this study discovered that privacy proclivity no longer has a significant direct impact …

Evaluation Of Roost Culling As A Management Strategy For Reducing Invasive Rose‑Ringed Parakeet (Psittacula Krameri) Populations, C. Janes Anderson, Leonard A. Brennan, William P. Bukoski, Steven C. Hess, Clayton D. Hilton, Aaron B. Shiels, Shane Siers, Bryan M. Kluever, Page E. Klug

United States Department of Agriculture Wildlife Services: Staff Publications

Rose-ringed parakeets (Psittacula krameri) are one of the most widespread invasive avian species worldwide. This species was introduced to the island of Kaua‘i, Hawai‘i, USA, in the 1960s. The rapidly increasing population has caused substantial economic losses in the agricultural and tourism industries. We evaluated the efficacy of a roost culling program conducted by an independent contractor from March 2020 to March 2021. We estimated island-wide minimum abundance was 10,512 parakeets in January 2020 and 7,372 in April 2021. Over 30 nights of culling at four roost sites, approximately 6,030 parakeets were removed via air rifles with 4,415 …

2023 State Of The Commonwealth Report, Vinod Agarwal, Aliou Ousmane Ba, Barbara Blake, James V. Koch, Ria Kolarao, Feng Lian, Anna Makhorkina, Melody Nguyen, Terry Parker, Mohamed Rahoui, Panagiotis Taoulas, Robert D. Mcnab

State of the Commonwealth Reports

This is Old Dominion University's ninth annual State of the Commonwealth Report. While it represents the work of many people connected in various ways to the University, the report does not constitute an official viewpoint of Old Dominion, its president, Brian Hemphill, Ph.D., the board of Visitors, the Strome College of Business or the generous donors who support the activities of the Dragas Center for Economic Analysis and Policy.

Our work seeks to contribute to the conversation about how Virginia can foster growth across the Commonwealth without glossing over the challenges we face. Instead of retreating into partisan enclaves where …

Factors Contributing To Ventilator Dependent Days In Covid-19, Isaac Ginsberg, Samantha Eteve, Bryan Lunt, Kenneth Krell

Continental, MidAmerica, & Mountain Divisions GME Research Day 2023

No abstract provided.

Foreword Introduction To Symposium: Enhancing Anti-Discrimination Laws In Education And Employment, Susan D. Carle

American University Journal of Gender, Social Policy & the Law

When this Symposium was first conceived in the Summer of 2021, the nation was just emerging from the first phases of the COVID-19 pandemic. This was the beginning of trying to go back to life as normal. Given this reawakening, the Symposium’s planning committee felt the urgency of a need to regroup, rethink, and reassess the state of employment antidiscrimination law. We were not sure where others would be on this possible project, given the newness of the hopeful end to lockdowns and social isolation and return to “normal” concerns. But we quickly found that those who joined the Symposium …

Covid-19 Return To Sport: Collegiate Baseball Injury Prevalence Analysis, Troy B. Puga, Joshua Schafer, Grace Thiel, Laura Ramaker, Tejas Patel, Kevin Treffer

Faculty and Staff Publications

In the spring of 2020, the COVID-19 pandemic rapidly brought college baseball to a halt. Most college baseball players saw disruption of their training and development due to interruptions of their seasons. With these interruptions, it is necessary to examine the effects of the COVID-19 pandemic on collegiate baseball injury epidemiology. Data from a small-school Midwest collegiate conference was tallied for the number of collegiate conference injuries per year, and for the injuries per anatomic region. An unpaired t-test was conducted upon the overall conference mean injuries per year and on each anatomic region for the mean injuries per region …

Clinicians' Perceptions Of Telehealth Services During The Covid-19 Pandemic In Virginia, Johnetta Hill Guishard

Walden Dissertations and Doctoral Studies

The onset of COVID-19 introduced unprecedented changes to how U.S. public health services were delivered. Many public and private agencies faced mandatory closures, social distancing mandates, and rapid transitions to telehealth interventions and treatment. Mental health clinicians witnessed disruptions in continuity of care and an increase in mental health risks overall. Although some studies have been conducted to survey clinicians’ perceptions of the usefulness and ease of use of technology-based interventions, knowledge about mental health clinicians’ experiences and perceptions in Virginia was sparse. The purpose of this generic qualitative study was to explore how mental health clinicians in Virginia described …

Covid-19 Crowd Detection, Mustafa Ibrahim, Aly M. Zeineldin, Yameen Khan, Ayman Elmesalami, Soad Ibrahim

OUR Journal: ODU Undergraduate Research Journal

Object detection was introduced by researchers for face detection. Researchers explain how the detected face is divided into minor frames to be recognized by the algorithm. Due to COVID-19 and government regulations, many people face problems going to shopping centers and shop safely. It has been very hard for both the government and the people to manage social distancing. In our study, we developed a system using Raspberry Pi-4 that will detect the distance between people along with counting the number of distance and mask violations. An error message will appear on the screen in red, showing the total number …

Parent Perspectives On How The Covid-19 Pandemic Affected Symptoms Of Autism Spectrum Disorder In Their Children, Desiree Marie Vanderlick

Walden Dissertations and Doctoral Studies

Autism is a disorder that is characterized by struggles with socialization anddevelopmental delays that often involve much guidance and support. The purpose of this study was to explain the experience of parents as they attempted to manage behaviors related to symptoms of autism during the worldwide quarantine prompted by COVID-19. This study aimed to close the gap in literature and explore to see if there were any concerns that could be addressed by future studies. The study was framed around Bowen’s theory, which addresses emotions within a family unit, and the interdependence theory, which addresses how humans thrive to be …

Occupational Burnout Factors Among Correctional Mental Health Providers, Morgan Gruhot

Walden Dissertations and Doctoral Studies

Burnout rates of correctional employees are higher than employees in the general public. The purpose of this study was to identify how occupational factors impact burnout rates among correctional mental health workers. Grounded in the job-demands theoretical model, this study compared burnout rates among mental health staff within county jails and state prisons. Burnout was measured using the Maslach Burnout Inventory and Occupational factors were measured using the Areas of Work life Survey and Pandemic Experience and Perception Survey. Data was analyzed using IBM SSPS software to address multiple a priori directional research questions. Research questions considered how occupational factors …

Impacts Of Covid-19 And The Policy Responses On The Aviation Industry., Islam Ahmed

Publications and Research

The objective of this paper is to explain the causal relationship between the impact of COVID-19 on the aviation sector and the policies initiated by the aviation authority such as the International Air Transport Authority (IATA), International Civil Aviation Organization (ICAO), the European Union Aviation Safety Agency (EASA) and the Federal Aviation Authority (FAA). COVID-19 affected every sector of the business world, and obviously, the aviation sector was not out of its effects. According to the Director General and CEO Alexandre de Juniac, “The aviation industry is in crisis. Our business connects people. But owing to efforts to control the …

The Relationship Between Ventilation Rates In Schools And The Indoor Airborne Transmission Potential Of Covid-19, Seamus Harrington, Mark Mulville, Spyros Stravoravdis

Articles

The requirement for natural ventilation strategies in classrooms to perform in respect to both their inherent and adaptive capacity is necessary to mitigate the risk of transmission associated with infectious airborne pathogens such as COVID-19. This paper assesses the performance of ten classrooms considering (a) the designed versus actual ventilation capacity; (b) the probability of airborne disease transmission by unit time resulting from calculated ventilation rates and (c) the reduction of transmission risk associated with mask wearing by all occupants.

Monitored air changes per hour (ACH) range from 0.26–1.7, demonstrating that none of the classrooms meet designed ventilation rate whilst …

Overlooked Sex And Gender Aspects Of Emerging Infectious Disease Outbreaks: Lessons Learned From Covid-19 To Move Towards Health Equity In Pandemic Response, Lynn Lieberman Lawry, Roberta Lugo-Robles, Vicki Mciver

Journal Articles: Epidemiology

Sex and gender issues are especially important in emerging infectious diseases (EIDs) but are routinely overlooked despite data and practice. Each of these have an effect either directly, via the effects on vulnerability to infectious diseases, exposures to infectious pathogens, and responses to illness, and indirectly through effects on disease prevention and control programs. The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the viral agent of coronavirus disease 2019 (COVID-19) has underscored the importance of understanding the sex and gender impacts on pandemics. This review takes a broader looks at how sex and gender impact vulnerability, exposure risk, and treatment and …

Nonsystematic Reporting Biases Of The Sars-Cov-2 Variant Mu Could Impact Our Understanding Of The Epidemiological Dynamics Of Emerging Variants, Mary E. Petrone, Carolina Lucas, Bridget Menasche, Mallery I. Breban, Inci Yildirim, Melissa Campbell, Saad B. Omer, Edward C. Holmes, Albert I. Ko, Nathan D. Grubaugh, Akiko Iwasaki, Craig B. Wilen, Chantal B. F. Vogels, Joseph R. Fauver

Journal Articles: Epidemiology

Developing a timely and effective response to emerging SARS-CoV-2 variants of concern (VOCs) is of paramount public health importance. Global health surveillance does not rely on genomic data alone to identify concerning variants when they emerge. Instead, methods that utilize genomic data to estimate the epidemiological dynamics of emerging lineages have the potential to serve as an early warning system. However, these methods assume that genomic data are uniformly reported across circulating lineages. In this study, we analyze differences in reporting delays among SARS-CoV-2 VOCs as a plausible explanation for the timing of the global response to the former VOC …

Bush V. Gore's Uniformity Principle And The 2020 Election, Michael T. Morley

Scholarly Publications

In Bush v. Gore, the Supreme Court established a Uniformity Principle for election administration, holding that the Equal Protection Clause prohibits arbitrary and disparate treatment of various voters participating in an election. Although the Court emphasized the limited scope of its holding, throughout the two decades that followed, lower courts have applied the Uniformity Principle in a variety of cases concerning the conduct of elections.

The principle was invoked in a wide range of cases throughout the 2020 election cycle, shedding further light on its contours. Some of these rulings may have been influenced by the unique circumstances of the …

Election Emergencies: Voting In Times Of Pandemic, Michael T. Morley

Scholarly Publications

Over the past century, two global pandemics have struck during American elections—the Spanish Flu of 1918 and COVID-19 in 2020. The legal system’s responses to these pandemics, occurring against very distinct constitutional backdrops concerning voting rights, differed dramatically from each other. These pandemics highlight the need for states to prepare to address not only public health crises, but election emergencies more broadly. States must adopt election emergency laws that both empower election officials to modify the rules of the electoral process as necessary to respond to these disasters, and also set forth “redlines,” identifying certain policies that, even in a …

Exploring The Impact Of Covid-19 On Adults With Intellectual And Developmental Disabilities In The United States, Sarah Lineberry

Theses and Dissertations

Like most disasters, the COVID-19 pandemic has disproportionately impacted people from historically marginalized communities. People with intellectual and developmental disabilities (IDD) have faced higher rates of infection, hospitalization, and death compared to people without disabilities, as well as significant disruptions to the services that support them to participate in the community. A relative lack of research about the experiences of people with IDD may have contributed to this risk and continues to limit our understanding of the impacts of COVID-19. This three-paper dissertation is guided by the theory of epistemic injustice (Fricker, 2007) to understand the impacts of COVID-19 on …

The Development Of Adolescent Students’ Self-Directed Learning Skills Within A Montessori Program During Covid-19: A Longitudinal Mixed-Methods Study, Elyse Laurelle Postlewaite

CGU Theses & Dissertations

Students who develop and apply their self-directed learning skills have advantages in school over those who do not (Betts & Knapp, 1981; Candy, 1991; Guglielmino, 1977; Schunk & Zimmerman, 2012). This is because self-directed learning (SDL) skills enable autonomous learning where students self-initiate, solve problems, develop new ideas, and monitor themselves with minimal external guidance (Knowles, 1976; Zimmerman, 2000). Despite the importance of these skills, research shows that few students consistently engage in SDL (Dent & Koenka, 2016; Zimmerman & Schunk, 2001). Because of SDL's multi-faceted and complex nature, it is difficult to discern why this is the case (Dent …

Virtual Teaching Kitchen Classes And Cardiovascular Disease Prevention Counselling Among Medical Trainees, Alexander C. Razavi, Anna Latoff, Amber Dyer, Jaclyn Lewis Albin, Kristi Artz, Alexandra Babcock, Francesca Cimino, Farzaneh Daghigh, Beth Dollinger, Maya Fiellin, Emily A. Johnston, Grace Marie Jones, Robert D. Karch, Emily T. Keller, Heather Nace, Nimisha K. Parekh, Stephanie Nelson Petrosky, Amy Robinson, Jessica Rosen, Eva M. Sheridan, Susan W. Warner, Jada L. Willis, Timothy S. Harlan

PCOM Scholarly Works

Background: Hands-on culinary medicine education for medical trainees has emerged as a promising tool for cardiovascular health promotion. Purpose: To determine whether virtual culinary medicine programming associates with Mediterranean diet (MedDiet) adherence and lifestyle medicine competencies among medical trainees across the USA. Method: A total of 1433 medical trainees across 19 sites over a 12-month period were included. The Cooking for Health Optimisation with Patients-Medical Trainees survey composed of 61 questions regarding demographics, nutritional attitudes, dietary habits including MedDiet score and lifestyle medicine counselling competencies. Multivariable logistic regression assessed the association of virtual culinary medicine education with MedDiet intake and …

Betacoronaviruses Sars-Cov-2 And Hcov-Oc43 Infections In Igrov-1 Cell Line Require Aryl Hydrocarbon Receptor, Meisam Yousefi, Wai Suet Lee, Wharton O.Y. Chan, Wei He, Marcus G. Mah, Cythia Lingli Yong, Joshua M. Deerain, Lijin Wang, Camille Arcinas, Biaoguo Yan, Dewei Tan, Wan Rong Sia, Akshamal M. Gamage, Jinxuan Yang, Alan Chen Yu Hsu, Shang Li, Martin Linster, Xinglou Yang, Sujoy Ghosh, Danielle E. Anderson, Gavin J.D. Smith, Chee Wah Tan, Lin Fa Wang, Yaw Shin Ooi

Division of Basic Science Faculty Publications

The emergence of novel betacoronaviruses has posed significant financial and human health burdens, necessitating the development of appropriate tools to combat future outbreaks. In this study, we have characterized a human cell line, IGROV-1, as a robust tool to detect, propagate, and titrate betacoronaviruses SARS-CoV-2 and HCoV-OC43. IGROV-1 cells can be used for serological assays, antiviral drug testing, and isolating SARS-CoV-2 variants from patient samples. Using time-course transcriptomics, we confirmed that IGROV-1 cells exhibit a robust innate immune response upon SARS-CoV-2 infection, recapitulating the response previously observed in primary human nasal epithelial cells. We performed genome-wide CRISPR knockout genetic screens …

A Leadership Perspective On Preventing Counselor Burnout In A Behavioral Health Setting During Covid-19, Claudia P. De La Torre

Walden Dissertations and Doctoral Studies

During the COVID-19 pandemic, there was a high need for mental health services, which resulted in a shortage of mental health clinicians. This shortage of mental health clinicians then resulted in a high burnout rate due to client intake. This doctoral case study was grounded in the Baldrige Excellence Framework and focused on how a behavioral health organization in South Texas managed burnout in clinicians during the COVID-19 pandemic. This study aimed to help behavioral health leaders find a solution to preventing burnout during a high demand pandemic. This doctoral study had several data sources, including semistructured interviews with three …

Structural Empowerment Of Nurse Leaders In New York State During The Covid-19 Pandemic, Tracey Braithwaite

Walden Dissertations and Doctoral Studies

The current phenomenological study explored the lived experience of Acting Chief Nursing Officers, Chief Nursing Officers, Chief Nursing Executives (henceforth CNOs) at hospitals in New York State who were charged with responding to executive orders while maintaining quality of patient care despite staffing constraints, inadequate supplies, or lack of additional support for the duties associated with their role. Their experience of structural empowerment in relation to the COVID-19 pandemic was also studied. The theoretical framework was Kanter’s theory of structural empowerment that addressed organizational behavior in the context of employee empowerment. The research question addressed how the CNOs perceived their …

Three Essays On Consumption Taxation In Indonesia, Partomuan Transparenter Juniult

Theses and Dissertations--Public Policy and Administration

Consumption taxes play a major role in revenue generation for many developing countries. They are also used to encourage or discourage certain consumption behaviors. However, the administrative aspects of implementing these taxes can create challenges for the tax authorities, and lead to distortions in taxpayer behavior. To overcome these challenges, efforts have been made to simplify policies and utilize technology to improve administration and compliance. My dissertation aims to provide empirical evidence on the effects of three consumption or commodity tax policy reforms in Indonesia. The dissertation consists of three essays as follows.

In my first essay, titled “The effect …

Examining The Home Interventionist Model Of Care In Pediatric Asthma, Katherine D. Lohr

Theses and Dissertations

Pediatric asthma disproportionately affects children living in urban areas and within families reporting an income below the poverty threshold. Home interventionist models of care, utilizing interventionists from the communities they serve, have been found to improve pediatric asthma symptoms and reduce Medicaid costs. Home interventionists, such as community health workers (CHWs) and Healthy Homes assessors (HHAs), focus on connecting care among schools, providers, and homes, and empowering families in accessing resources to overcome barriers to care. However, research is just beginning to understand how home interventionists create positive change among families within low-income, urban communities. This dissertation study used a …