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An Integrated Cell Atlas Of The Lung In Health And Disease, Lisa Sikkema, Ciro Ramírez-Suástegui, Daniel C Strobl, Tessa E Gillett, Luke Zappia, Elo Madissoon, Nikolay S Markov, Laure-Emmanuelle Zaragosi, Yuge Ji, Meshal Ansari, Marie-Jeanne Arguel, Leonie Apperloo, Martin Banchero, Christophe Bécavin, Marijn Berg, Evgeny Chichelnitskiy, Mei-I Chung, Antoine Collin, Aurore C A Gay, Janine Gote-Schniering, Baharak Hooshiar Kashani, Kemal Inecik, Manu Jain, Theodore S Kapellos, Tessa M Kole, Sylvie Leroy, Christoph H Mayr, Amanda J Oliver, Michael Von Papen, Lance Peter, Chase J Taylor, Thomas Walzthoeni, Chuan Xu, Linh T Bui, Carlo De Donno, Leander Dony, Alen Faiz, Minzhe Guo, Austin J Gutierrez, Lukas Heumos, Ni Huang, Ignacio L Ibarra, Nathan D Jackson, Preetish Kadur Lakshminarasimha Murthy, Mohammad Lotfollahi, Tracy Tabib, Carlos Talavera-López, Kyle J Travaglini, Anna Wilbrey-Clark, Kaylee B Worlock, Masahiro Yoshida, Maarten Van Den Berge, Yohan Bossé, Tushar J Desai, Oliver Eickelberg, Naftali Kaminski, Mark A Krasnow, Robert Lafyatis, Marko Z Nikolic, Joseph E Powell, Jayaraj Rajagopal, Mauricio Rojas, Orit Rozenblatt-Rosen, Max A Seibold, Dean Sheppard, Douglas P Shepherd, Don D Sin, Wim Timens, Alexander M Tsankov, Jeffrey Whitsett, Yan Xu, Nicholas E Banovich, Pascal Barbry, Thu Elizabeth Duong, Christine S Falk, Kerstin B Meyer, Jonathan A Kropski, Dana Pe'er, Herbert B Schiller, Purushothama Rao Tata, Joachim L Schultze, Sara A Teichmann, Alexander V Misharin, Martijn C Nawijn, Malte D Luecken, Fabian J Theis Jun 2023

An Integrated Cell Atlas Of The Lung In Health And Disease, Lisa Sikkema, Ciro Ramírez-Suástegui, Daniel C Strobl, Tessa E Gillett, Luke Zappia, Elo Madissoon, Nikolay S Markov, Laure-Emmanuelle Zaragosi, Yuge Ji, Meshal Ansari, Marie-Jeanne Arguel, Leonie Apperloo, Martin Banchero, Christophe Bécavin, Marijn Berg, Evgeny Chichelnitskiy, Mei-I Chung, Antoine Collin, Aurore C A Gay, Janine Gote-Schniering, Baharak Hooshiar Kashani, Kemal Inecik, Manu Jain, Theodore S Kapellos, Tessa M Kole, Sylvie Leroy, Christoph H Mayr, Amanda J Oliver, Michael Von Papen, Lance Peter, Chase J Taylor, Thomas Walzthoeni, Chuan Xu, Linh T Bui, Carlo De Donno, Leander Dony, Alen Faiz, Minzhe Guo, Austin J Gutierrez, Lukas Heumos, Ni Huang, Ignacio L Ibarra, Nathan D Jackson, Preetish Kadur Lakshminarasimha Murthy, Mohammad Lotfollahi, Tracy Tabib, Carlos Talavera-López, Kyle J Travaglini, Anna Wilbrey-Clark, Kaylee B Worlock, Masahiro Yoshida, Maarten Van Den Berge, Yohan Bossé, Tushar J Desai, Oliver Eickelberg, Naftali Kaminski, Mark A Krasnow, Robert Lafyatis, Marko Z Nikolic, Joseph E Powell, Jayaraj Rajagopal, Mauricio Rojas, Orit Rozenblatt-Rosen, Max A Seibold, Dean Sheppard, Douglas P Shepherd, Don D Sin, Wim Timens, Alexander M Tsankov, Jeffrey Whitsett, Yan Xu, Nicholas E Banovich, Pascal Barbry, Thu Elizabeth Duong, Christine S Falk, Kerstin B Meyer, Jonathan A Kropski, Dana Pe'er, Herbert B Schiller, Purushothama Rao Tata, Joachim L Schultze, Sara A Teichmann, Alexander V Misharin, Martijn C Nawijn, Malte D Luecken, Fabian J Theis

Faculty, Staff and Student Publications

Single-cell technologies have transformed our understanding of human tissues. Yet, studies typically capture only a limited number of donors and disagree on cell type definitions. Integrating many single-cell datasets can address these limitations of individual studies and capture the variability present in the population. Here we present the integrated Human Lung Cell Atlas (HLCA), combining 49 datasets of the human respiratory system into a single atlas spanning over 2.4 million cells from 486 individuals. The HLCA presents a consensus cell type re-annotation with matching marker genes, including annotations of rare and previously undescribed cell types. Leveraging the number and diversity …


Covid-19 Vaccines And The Pandemic: Lessons Learnt For Other Neglected Diseases And Future Threats, Peter J Hotez, Sarah Gilbert, Melanie Saville, Lois Privor-Dumm, Salim Abdool-Karim, Didi Thompson, Jean-Louis Excler, Jerome H Kim Jun 2023

Covid-19 Vaccines And The Pandemic: Lessons Learnt For Other Neglected Diseases And Future Threats, Peter J Hotez, Sarah Gilbert, Melanie Saville, Lois Privor-Dumm, Salim Abdool-Karim, Didi Thompson, Jean-Louis Excler, Jerome H Kim

Faculty, Staff and Students Publications

Through the experiences gained by accelerating new vaccines for both Ebola virus infection and COVID-19 in a public health emergency, vaccine development has benefited from a 'multiple shots on goal' approach to new vaccine targets. This approach embraces simultaneous development of candidates with differing technologies, including, when feasible, vesicular stomatitis virus or adenovirus vectors, messenger RNA (mRNA), whole inactivated virus, nanoparticle and recombinant protein technologies, which led to multiple effective COVID-19 vaccines. The challenge of COVID-19 vaccine inequity, as COVID-19 spread globally, created a situation where cutting-edge mRNA technologies were preferentially supplied by multinational pharmaceutical companies to high-income countries while …


Prognostic Value Of Severe Acute Respiratory Syndrome Coronavirus-2 Viral Load And Antibodies In Patients Hospitalized With Covid-19, Rebecca N Bauer, Anastasia Teterina, Haridha Shivram, Jacqueline Mcbride, Carrie M Rosenberger, Fang Cai, Min Bao, Larry Tsai, Oliver Gordon, Ivan T Lee, Jeffrey J Wallin, Danielle Porter, Kavita Juneja, Gregory Camus, Ivan O Rosas, Steffen Wildum Jun 2023

Prognostic Value Of Severe Acute Respiratory Syndrome Coronavirus-2 Viral Load And Antibodies In Patients Hospitalized With Covid-19, Rebecca N Bauer, Anastasia Teterina, Haridha Shivram, Jacqueline Mcbride, Carrie M Rosenberger, Fang Cai, Min Bao, Larry Tsai, Oliver Gordon, Ivan T Lee, Jeffrey J Wallin, Danielle Porter, Kavita Juneja, Gregory Camus, Ivan O Rosas, Steffen Wildum

Faculty, Staff and Students Publications

Observational studies have identified the potential prognostic value for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) viral load and anti-SARS-CoV-2 antibodies in coronavirus disease 2019 (COVID-19). However, viral load in nasopharyngeal (NP) swabs produced inconsistent results in prognostic analyses, and the prognostic value of viral load or antibodies has not been confirmed in large clinical trials. COVACTA and REMDACTA were double-blind, randomized, controlled trials with a combined enrollment of 1078 patients hospitalized with COVID-19 treated with tocilizumab or placebo in COVACTA or tocilizumab plus remdesivir or placebo plus remdesivir in REMDACTA. We assessed the potential prognostic value of NP and serum …


Elizabeth Fitt, Oral History Interview, 2023, You Li May 2023

Elizabeth Fitt, Oral History Interview, 2023, You Li

Collective Memory of Women Journalists in COVID-19

Elizabeth Fitt is a freelance photographer based out of Beirut, Lebanon. Her work has been published with various media outlets including the Guardian, the Sunday Times, Forbes, Foreign Policy, the Telegraph, CNN, ABC Australia, The National, Middle East Eye, The New Humanitarian, The New York Post, and the New Scientist. She also writes on environmental issues for Mongabay.

In this interview, Fitt recalled the ground situation in Lebanon and the extreme caution and effort it took her to photograph vulnerable communities during lockdowns. Her projects depicted the overwhelming and devastating scenes in the ICU Wards, the food distribution among the …


Binge Drinking Alcohol And Circadian Misalignment In Night Shift Nurses Is Associated With Decreased Resiliency To Covid-19 Infection, Garth R. Swanson, Benjamin A. Schwartz, Cara Joyce, Ali Keshavarzian May 2023

Binge Drinking Alcohol And Circadian Misalignment In Night Shift Nurses Is Associated With Decreased Resiliency To Covid-19 Infection, Garth R. Swanson, Benjamin A. Schwartz, Cara Joyce, Ali Keshavarzian

Biostatistics Collaborative Core: Faculty Publications and Other Works

Background: Nurses and other first responders are at high risk of exposure to the SARS-CoV2 virus, and many have developed severe COVID-19 infection. A better understanding of the factors that increase the risk of infection after exposure to the virus could help to address this. Although several risk factors such as obesity, diabetes, and hypertension have been associated with an increased risk of infection, many first responders develop severe COVID-19 without established risk factors. As inflammation and cytokine storm are the primary mechanisms in severe COVID-19, other factors that promote an inflammatory state could increase the risk of COVID-19 in …


Telehealth Fraud And Abuse Before And “After” The Pandemic: Are Things Going To Get Better?, Natalia Shamuel May 2023

Telehealth Fraud And Abuse Before And “After” The Pandemic: Are Things Going To Get Better?, Natalia Shamuel

DePaul Journal of Health Care Law

Telehealth and telemedicine have become increasingly useful to both patients and health care providers. The ease and comfort of attending a doctor’s appointment in the comfort of one’s own home made telehealth and telemedicine convenient, safe, and effective options for seeing a doctor during the height of the COVID-19 pandemic. However, with increased usage of telehealth and telemedicine came increased health care fraud and abuse. With increased health care fraud and abuse came increased regulations, both on the federal and state levels. This Note provides a brief analysis of health care fraud and abuse in the telehealth and telemedicine space. …


Danielle Keeton-Olsen, Oral History Interview, 2023, You Li May 2023

Danielle Keeton-Olsen, Oral History Interview, 2023, You Li

Collective Memory of Women Journalists in COVID-19

Danielle Keeton-Olsen is a freelance journalist who explores issues in business, human rights, healthcare, and environmental subjects in Cambodia. She has been stationed in Cambodia since 2017. Her work has been published in Forbes, the BBC, South China Morning Post, VOD English, Al Jazeera, and HuffPost, among others.

In this interview, Keeton-Olsen recalled the ground situation in January 2020 and the COVID impact on local communities and businesses in Cambodia. She reviewed her journey of becoming a foreign correspondent. She commented on the business model of Cambodian media, the media environment, government control of media, media relationship with the general …


Megan Clement, Oral History Interview, 2023, You Li May 2023

Megan Clement, Oral History Interview, 2023, You Li

Collective Memory of Women Journalists in COVID-19

Megan Clement from Montreuil, France, is a journalist, critic, and editor whose work focuses on gender equality, social policy, migration, human rights, arts, and culture. Her work has appeared in The Guardian, Bloomberg, The Sydney Morning Herald, Al Jazeera, The New Humanitarian, and News Deeply, among other publications.

Clement, an Australian journalist living in Paris, France at the time, traveled across three continents and underwent four quarantines for work and family reasons during the pandemic. She published her quarantine experiences in the first-person voice and raised public attention to the mismanagement of quarantine protocols at hotels and public housing. She …


Participation Of Academic Libraries And Provision Of Covid-19 Information Services During The Pandemic In Nigeria, Flora Orewa May 2023

Participation Of Academic Libraries And Provision Of Covid-19 Information Services During The Pandemic In Nigeria, Flora Orewa

Library Philosophy and Practice (e-journal)

Information was sought on the level of collaboration between academic libraries and known key players championing the prevention and control of COVID-19, the activities carried out in compliance with set protocols, information services offered, and the challenges faced. Results showed moderate level of collaboration and very limited direct synergistic interaction with public health groups, while they provided patrons with an avenue to source updates from library websites. There was high compliance with COVID-19 prevention guidelines; however, there was no specialized COVID-19 information service desk for patrons' inquiries. Libraries participated in the dissemination of COVID-19 information during the pandemic, especially to …


Blockchain-Enabled Immutable, Distributed, And Highly Available Clinical Research Activity Logging System For Federated Covid-19 Data Analysis From Multiple Institutions, Tsung-Ting Kuo, Anh Pham, Maxim E Edelson, Jihoon Kim, Jason Chan, Yash Gupta, Lucila Ohno-Machado May 2023

Blockchain-Enabled Immutable, Distributed, And Highly Available Clinical Research Activity Logging System For Federated Covid-19 Data Analysis From Multiple Institutions, Tsung-Ting Kuo, Anh Pham, Maxim E Edelson, Jihoon Kim, Jason Chan, Yash Gupta, Lucila Ohno-Machado

Faculty, Staff and Student Publications

OBJECTIVE: We aimed to develop a distributed, immutable, and highly available cross-cloud blockchain system to facilitate federated data analysis activities among multiple institutions.

MATERIALS AND METHODS: We preprocessed 9166 COVID-19 Structured Query Language (SQL) code, summary statistics, and user activity logs, from the GitHub repository of the Reliable Response Data Discovery for COVID-19 (R2D2) Consortium. The repository collected local summary statistics from participating institutions and aggregated the global result to a COVID-19-related clinical query, previously posted by clinicians on a website. We developed both on-chain and off-chain components to store/query these activity logs and their associated queries/results on a blockchain …


Denise Hruby, Oral History Interview, 2023, You Li May 2023

Denise Hruby, Oral History Interview, 2023, You Li

Collective Memory of Women Journalists in COVID-19

Denise Hruby from Vienna, Austria, is an award-winning journalist, writer, and National Geographic Explorer focusing on the climate and biodiversity crises and politics. Her work has appeared in The New York Times, National Geographic Magazine, The Washington Post, and CNN, among many others. She has won multiple international awards for environmental reporting and feature writing and numerous fellowships and grants. Throughout her career, Denise has reported from more than 25 countries, including the war in Ukraine, terror attacks in Austria, and conflicts in South Sudan among many other national and international events. Before relocating to Vienna in 2018, Denise worked …


Frankie Huang, Oral History Interview, 2023, You Li May 2023

Frankie Huang, Oral History Interview, 2023, You Li

Collective Memory of Women Journalists in COVID-19

Frankie Huang from the United States is a freelance writer, editor, strategist, and illustrator. She writes about culture and food, and she is interested in intersectional feminism, diaspora Asian American identity, social justice, storytelling, the hybrid of translation and creation, and beauty in all its forms. Her work has been published in The Atlantic, The New York Times, The Guardian, Foreign Policy, and 1843 Magazine, among many others.

Huang published a few opinion pieces based on her experience in Shanghai in the early days of the pandemic and then returning to the U.S. In this interview, she recalled her journey …


Beyond Response: Reimagining The Legal Academy's Role In Disaster Recovery And Preparedness, Latisha Nixon-Jones May 2023

Beyond Response: Reimagining The Legal Academy's Role In Disaster Recovery And Preparedness, Latisha Nixon-Jones

Cleveland State Law Review

This Article proposes expanding the legal academy’s role in responding to disasters and emergencies, specifically through creating disaster clinics that take a community-based lawyering approach. The Article is one of the first to identify the need for community-based disaster legal clinical education that goes beyond the immediate response phase. It also proposes creating a disaster legal pipeline from the clinic through post-graduation employment. The Article furthers the literature’s discussion of the need for sustained disaster legal education. As the global pandemic caused by COVID-19 coronavirus continues to impact vulnerable populations and the frequency of natural disasters continues to increase, this …


Protocol For Developing A Personalised Prediction Model For Viral Suppression Among Under-Represented Populations In The Context Of The Covid-19 Pandemic, Jiajia Zhang Ph.D., Xueying Yang Ph.D., Sharon Weissman, Xiaoming Li Ph.D., Bankole Olatosi Ph.D. May 2023

Protocol For Developing A Personalised Prediction Model For Viral Suppression Among Under-Represented Populations In The Context Of The Covid-19 Pandemic, Jiajia Zhang Ph.D., Xueying Yang Ph.D., Sharon Weissman, Xiaoming Li Ph.D., Bankole Olatosi Ph.D.

Faculty Publications

Introduction Sustained viral suppression, an indicator of long-term treatment success and mortality reduction, is one of four strategic areas of the 'Ending the HIV Epidemic' federal campaign launched in 2019. Under-represented populations, like racial or ethnic minority populations, sexual and gender minority groups, and socioeconomically disadvantaged populations, are disproportionately affected by HIV and experience a more striking virological failure. The COVID-19 pandemic might magnify the risk of incomplete viral suppression among under-represented people living with HIV (PLWH) due to interruptions in healthcare access and other worsened socioeconomic and environmental conditions. However, biomedical research rarely includes under-represented populations, resulting in biased …


Development Of Recombinant Varicella-Zoster Virus Vaccines Expressing Sars-Cov-2 Antigens, Cody Wilson May 2023

Development Of Recombinant Varicella-Zoster Virus Vaccines Expressing Sars-Cov-2 Antigens, Cody Wilson

Honors Theses

The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2) continues to cause infections and deaths around the globe. Since its emergence, scientists have worked diligently to discover and produce vaccines to battle the virus. While they successfully created and distributed vaccines, the vaccines are not without flaw. These vaccines do not grant long term immunity, require multiple booster shots, and have not prevented the emergence of viral variants. In this study, the SARS-CoV-2 receptor binding domain (RBD), which is a key part of the spike protein (S), and nucleocapsid (N) genetic sequences were inserted into the live varicella …


The Essence Of K-12 Teaching In A Catholic Archdiocese In Kentucky During The Covid-19 Pandemic, Danielle Atzinger Wiegandt May 2023

The Essence Of K-12 Teaching In A Catholic Archdiocese In Kentucky During The Covid-19 Pandemic, Danielle Atzinger Wiegandt

Graduate Theses, Dissertations, and Capstones

Even before the COVID-19 pandemic research showed that teacher attrition among new teachers (less than five years) was a problem for schools throughout the country and Catholic Schools were facing an even higher rate (Ingersoll, 2003). Research also shows that there are often cultural and structural components of Catholic schools that influence teachers to stay (Youngs, 2013; Convey, 2012, 2014). The COVID-19 pandemic forced the education system to pivot and teachers are expected to continue to have high standards for education while making these shifts.

In the early period of COVID-19 pandemic research was already suggesting attrition rates were rising …


A Computationally Designed Ace2 Decoy Has Broad Efficacy Against Sars-Cov-2 Omicron Variants And Related Viruses In Vitro And In Vivo, Brandon Havranek, Graeme Walker Lindsey, Yusuke Higuchi, Yumi Itoh, Tatsuya Suzuki, Toru Okamoto, Atsushi Hoshino, Erik Procko, Shahidul M. Islam May 2023

A Computationally Designed Ace2 Decoy Has Broad Efficacy Against Sars-Cov-2 Omicron Variants And Related Viruses In Vitro And In Vivo, Brandon Havranek, Graeme Walker Lindsey, Yusuke Higuchi, Yumi Itoh, Tatsuya Suzuki, Toru Okamoto, Atsushi Hoshino, Erik Procko, Shahidul M. Islam

SKMC Student Presentations and Publications

SARS-CoV-2, especially B.1.1.529/omicron and its sublineages, continues to mutate to evade monoclonal antibodies and antibodies elicited by vaccination. Affinity-enhanced soluble ACE2 (sACE2) is an alternative strategy that works by binding the SARS-CoV-2 S protein, acting as a 'decoy' to block the interaction between the S and human ACE2. Using a computational design strategy, we designed an affinity-enhanced ACE2 decoy, FLIF, that exhibited tight binding to SARS-CoV-2 delta and omicron variants. Our computationally calculated absolute binding free energies (ABFE) between sACE2:SARS-CoV-2 S proteins and their variants showed excellent agreement to binding experiments. FLIF displayed robust therapeutic utility against a broad range …


Health Professional Well-Being And Preparedness During The Covid-19 Pandemic In Trinidad And Tobago: An Online Survey, Loren De Freitas, Darren Dookeeram, Shastri Motilal May 2023

Health Professional Well-Being And Preparedness During The Covid-19 Pandemic In Trinidad And Tobago: An Online Survey, Loren De Freitas, Darren Dookeeram, Shastri Motilal

Journal of Wellness

Introduction: Poor well-being impacts mental health and subsequently affects personal lives, leads to absenteeism, poor productivity, and compromised patient safety. Frontline healthcare workers are highly vulnerable to COVID-19 pandemic-related mental health strain. This study assessed the well-being and preparedness of frontline healthcare workers in Trinidad and Tobago during the pandemic.

Methods: An online cross-sectional survey was sent to doctors, nurses, and prehospital providers from public and private healthcare sectors. Data was collected from May to June 2020 utilizing a self- administered online platform. The WHO Five Well-being Index (WHO-5) was used to assess well-being. Raw scores less than 13 indicated …


The Impact Of Covid-19 On Para-Athletes: A Case Study On Motivation And Psychological Training For The 2020 Paralympic Games, Irina Perfilova May 2023

The Impact Of Covid-19 On Para-Athletes: A Case Study On Motivation And Psychological Training For The 2020 Paralympic Games, Irina Perfilova

Masters Theses, 2020-current

In the 61-year history of the Paralympic Games, the Games have never been canceled for any public health reasons. In order to participate in the Paralympic Games, the preparation process for professional athletes is planned at least four years in advance. Interruptions to this schedule can present significant challenges for elite athletes. Such was the case in 2020 with widespread cancellations of many athletic events due to the COVID-19 pandemic. The impact of in-home isolation can potentially cause athletes to experience different psychological conditions, including depression and anxiety as well as losing motivation. The purpose of this study was to …


Social And Emotional Development Of Toddlers Post-Covid-19 Pandemic, Alice M. Bygd May 2023

Social And Emotional Development Of Toddlers Post-Covid-19 Pandemic, Alice M. Bygd

Counselor Education Capstones

The COVID-19 pandemic created a significantly different world for infants and very young children to grow and develop their social and emotional skills. These infants are now today’s toddlers. They were born or spent the earliest months of their lives in a society that was lacking the naturally occurring social and emotional experiences that children have had in the past. Research on the social and emotional development of young children since the COVID-19 pandemic is lacking greatly. This is due to how close the lived experiences of a pandemic for society are to the beginning of the COVID-19 pandemic. The …


Amanda Morris, Oral History Interview, 2023, You Li May 2023

Amanda Morris, Oral History Interview, 2023, You Li

Collective Memory of Women Journalists in COVID-19

Amanda Morris is a staff reporter at the Washington Post in the United States. Before joining the Post in August 2022, Morris was an inaugural disability reporting fellow for The New York Times. Previously, she covered science, politics, and national news for outlets, including The Arizona Republic, The Associated Press, and National Public Radio (NPR).

In this interview Morris shared her experiences covering the early months of the pandemic for The Arizona Republic. She recalled challenges such as performing field work as a visual journalist, maintaining work and work-life balance, mental health, and combating public distrust in science reporting and …


College Student Depression Throughout Covid-19: Fall 2019-Spring 2022, Matthew Powless, Zachary Pilot, Valentin Bouvier, Elisabeth Brown, Mikaila Ealum, Lakota Iron Rope May 2023

College Student Depression Throughout Covid-19: Fall 2019-Spring 2022, Matthew Powless, Zachary Pilot, Valentin Bouvier, Elisabeth Brown, Mikaila Ealum, Lakota Iron Rope

Midwest Social Sciences Journal

The current study examined the trends in depression and emotion regulation for students (n = 899) at one university in the Midwest United States from prior to the COVID-19 pandemic (Fall 2019) through the Spring 2022 semester. An analysis of covariance (ANCOVA) was conducted, controlling for difficulties in emotion regulation and gender identity. The ANCOVA indicated that depression was significantly lower in Fall 2019 than in the remaining five semesters under investigation. Results of these analyses appear to indicate that depression rose significantly in students after the onset of the pandemic and implementation of social restrictions. This negative effect …


Observational Study Of Organisational Responses Of 17 Us Hospitals Over The First Year Of The Covid-19 Pandemic, Esther K. Choo, Matthew Strehlow, Marina Del Rios, Evrim Oral, Ruth Pobee, Andrew Nugent, Stephen C. Lim, Christian Hext, Sarah Newhall, Diana Ko, Srihari V. Chari, Amy Wilson, Joshua J. Baugh, David Callaway, Mucio Kit Delgado, Zoe Glick, Christian J. Graulty, Nicholas Hall, Abdusebur Jemal, Madhav Kc, Aditya Mahadevan, Milap Mehta, Andrew C. Meltzer, Dar'ya Pozhidayeva, Daniel Resnick-Ault May 2023

Observational Study Of Organisational Responses Of 17 Us Hospitals Over The First Year Of The Covid-19 Pandemic, Esther K. Choo, Matthew Strehlow, Marina Del Rios, Evrim Oral, Ruth Pobee, Andrew Nugent, Stephen C. Lim, Christian Hext, Sarah Newhall, Diana Ko, Srihari V. Chari, Amy Wilson, Joshua J. Baugh, David Callaway, Mucio Kit Delgado, Zoe Glick, Christian J. Graulty, Nicholas Hall, Abdusebur Jemal, Madhav Kc, Aditya Mahadevan, Milap Mehta, Andrew C. Meltzer, Dar'ya Pozhidayeva, Daniel Resnick-Ault

School of Public Health Faculty Publications

Objectives The COVID-19 pandemic has required significant modifications of hospital care. The objective of this study was to examine the operational approaches taken by US hospitals over time in response to the COVID-19 pandemic. Design, setting and participants This was a prospective observational study of 17 geographically diverse US hospitals from February 2020 to February 2021. Outcomes and analysis We identified 42 potential pandemic-related strategies and obtained week-to-week data about their use. We calculated descriptive statistics for use of each strategy and plotted percent uptake and weeks used. We assessed the relationship between strategy use and hospital type, geographic region …


Compassion Fatigue In An Infodemic: A Physician’S Duty To Treat In The Age Of Misinformation, Alessandra Perez May 2023

Compassion Fatigue In An Infodemic: A Physician’S Duty To Treat In The Age Of Misinformation, Alessandra Perez

University of Miami International and Comparative Law Review

This Note considers how misinformation has exacerbated the COVID-19 pandemic and the inevitable burden it has placed on the healthcare industry. It explores the intersection between a doctor’s oath of ethics and their right to refuse care by uncovering the obligations that guide their decisions. Justice dictates that physicians provide care to all who seek it, and it is unconstitutional for a physician to refuse to treat patients based on race, ethnicity, gender, religion, or sexual orientation. Even if a patient’s request is antithetical to a physician’s personal beliefs, the unwavering duty to treat generally mandates that physicians treat any …


Telehealth Monitoring For Non-Hospitalized Covid-19 Positive Patients In A Rural Setting, Rebekah Leann French May 2023

Telehealth Monitoring For Non-Hospitalized Covid-19 Positive Patients In A Rural Setting, Rebekah Leann French

Doctor of Nursing Practice Scholarly Projects

Purpose

This quality improvement project evaluates the efficacy of an outpatient COVID-19 telehealth monitoring program intended to increase access to care, decrease emergency room/urgent care visits, and hospital admissions among telehealth observed adult patients in a rural area while providing safe home monitoring during acute illness.

Rationale/Background

Prior to COVID-19 pandemic, healthcare systems within the United States encountered several challenges including healthcare inequality and decreased healthcare access, particularly in rural communities. These gaps became more apparent when a novel COVID-19 pandemic emerged straining healthcare systems in the United States and throughout the world. Challenges ranged from overwhelmed emergency room (ER) …


Review Of Telemedicine Use As It Expands Since The Covid-19 Pandemic, Michael P. Perra, Frederick J. Goldstein May 2023

Review Of Telemedicine Use As It Expands Since The Covid-19 Pandemic, Michael P. Perra, Frederick J. Goldstein

Research Day

INTRODUCTION: As new technology advances and the world becomes increasingly connected, medical care and physician-patient interactions have changed. Telemedicine, though present in different forms for many decades, has grown, and its use is changing at a faster-than-ever pace. The COVID-19 pandemic highlighted the utility of different telemedicine platforms and has led to an expansion in its capabilities.

OBJECTIVES: To explore the evolution of telemedicine, its multiple functions, and how this technology has continued to develop since the COVID-19 pandemic in various medical specialties.

METHODS: PubMed was used to assess published studies that either incorporated telehealth resources in their research or …


Higher Risk Of Short Term Covid-19 Vaccine Adverse Events In Myositis Patients With Autoimmune Comorbidities: Results From The Covad Study, Mrinalini Dey, Naveen R, Elena Nikiphorou, Parikshit Sen, Sreoshy Saha, James B Lilleker, Vishwesh Agarwal, Sinan Kardes, Jessica Day, Marcin Milchert, Mrudula Joshi, Tamer Gheita, Babur Salim, Tsvetelina Velikova, Abraham Edgar Gracia-Ramos, Ioannis Parodis, Albert Selva O'Callaghan, Minchul Kim, Tulika Chatterjee, Ai Lyn Tan, Ashima Makol, Arvind Nune, Lorenzo Cavagna, Miguel A Saavedra, Samuel Katsuyuki Shinjo, Nelly Ziade, Johannes Knitza, Masataka Kuwana, Oliver Distler, Bhupen Barman, Yogesh Preet Singh, Rajiv Ranjan, Avinash Jain, Sapan C Pandya, Rakesh Kumar Pilania, Aman Sharma, Manesh M Manoj, Vikas Gupta, Chengappa G Kavadichanda, Pradeepta Sekhar Patro, Sajal Ajmani, Sanat Phatak, Rudra Prosad Goswami, Abhra Chandra Chowdhury, Ashish Jacob Mathew, Padnamabha Shenoy, Ajay Asranna, Keerthi Talari Bommakanti, Anuj Shukla, Arunkumar R Pande, Kunal Chandwar, John D Pauling, Chris Wincup, Döndü Üsküdar Cansu, Erick Adrian Zamora Tehozol, Jorge Rojas Serrano, Ignacio García-De La Torre, Nicoletta Del Papa, Gianluca Sambataro, Atzeni Fabiola, Marcello Govoni, Simone Parisi, Elena Bartoloni Bocci, Gian Domenico Sebastiani, Enrico Fusaro, Marco Sebastiani, Luca Quartuccio, Franco Franceschini, Pier Paolo Sainaghi, Giovanni Orsolini, Rossella De Angelis, Maria Giovanna Danielli, Vincenzo Venerito, Lisa S Traboco, Leonardo Santos Hoff, Suryo Anggoro Kusumo Wibowo, Stylianos Tomaras, Daman Langguth, Vidya Limaye, Merrilee Needham, Nilesh Srivastav, Akira Yoshida, Ran Nakashima, Shinji Sato, Naoki Kimura, Yuko Kaneko, Jesús Loarce-Martos, Sergio Prieto-González, Albert Gil-Vila, Raquel Arànega Gonzalez, Hector Chinoy, Vikas Agarwal, Rohit Aggarwal, Latika Gupta May 2023

Higher Risk Of Short Term Covid-19 Vaccine Adverse Events In Myositis Patients With Autoimmune Comorbidities: Results From The Covad Study, Mrinalini Dey, Naveen R, Elena Nikiphorou, Parikshit Sen, Sreoshy Saha, James B Lilleker, Vishwesh Agarwal, Sinan Kardes, Jessica Day, Marcin Milchert, Mrudula Joshi, Tamer Gheita, Babur Salim, Tsvetelina Velikova, Abraham Edgar Gracia-Ramos, Ioannis Parodis, Albert Selva O'Callaghan, Minchul Kim, Tulika Chatterjee, Ai Lyn Tan, Ashima Makol, Arvind Nune, Lorenzo Cavagna, Miguel A Saavedra, Samuel Katsuyuki Shinjo, Nelly Ziade, Johannes Knitza, Masataka Kuwana, Oliver Distler, Bhupen Barman, Yogesh Preet Singh, Rajiv Ranjan, Avinash Jain, Sapan C Pandya, Rakesh Kumar Pilania, Aman Sharma, Manesh M Manoj, Vikas Gupta, Chengappa G Kavadichanda, Pradeepta Sekhar Patro, Sajal Ajmani, Sanat Phatak, Rudra Prosad Goswami, Abhra Chandra Chowdhury, Ashish Jacob Mathew, Padnamabha Shenoy, Ajay Asranna, Keerthi Talari Bommakanti, Anuj Shukla, Arunkumar R Pande, Kunal Chandwar, John D Pauling, Chris Wincup, Döndü Üsküdar Cansu, Erick Adrian Zamora Tehozol, Jorge Rojas Serrano, Ignacio García-De La Torre, Nicoletta Del Papa, Gianluca Sambataro, Atzeni Fabiola, Marcello Govoni, Simone Parisi, Elena Bartoloni Bocci, Gian Domenico Sebastiani, Enrico Fusaro, Marco Sebastiani, Luca Quartuccio, Franco Franceschini, Pier Paolo Sainaghi, Giovanni Orsolini, Rossella De Angelis, Maria Giovanna Danielli, Vincenzo Venerito, Lisa S Traboco, Leonardo Santos Hoff, Suryo Anggoro Kusumo Wibowo, Stylianos Tomaras, Daman Langguth, Vidya Limaye, Merrilee Needham, Nilesh Srivastav, Akira Yoshida, Ran Nakashima, Shinji Sato, Naoki Kimura, Yuko Kaneko, Jesús Loarce-Martos, Sergio Prieto-González, Albert Gil-Vila, Raquel Arànega Gonzalez, Hector Chinoy, Vikas Agarwal, Rohit Aggarwal, Latika Gupta

Faculty, Staff and Student Publications

No abstract provided.


The Impact Of Covid-19 On Accountants: Evidence From Saudi Arabia, N. A. Alessa, H. S. Shalhoob May 2023

The Impact Of Covid-19 On Accountants: Evidence From Saudi Arabia, N. A. Alessa, H. S. Shalhoob

Journal of Statistics Applications & Probability

The current research aimed to investigate the impact of COVID-19 quarantine periods on accountants’ performance and remote work environment in Saudi Arabia. Additionally, it aimed to examine government and professional bodies support and its implications on accountants adaptability to the changing work environment. Following a descriptive analytical research design, the research utilized a structured questionnaire survey to collect data. The participants were (1,086) accountants responded to the questionnaire. The research was conducted during the years 2020/2021. Results indicated COVID-19 had a large positive impact on accountants performance, whereas it had a negative impact on reducing the scope of work and …


The Effects Of The Covid-19 Pandemic On Mergers And Acquisitions, Goodwill, And Goodwill Impairment In The Technology Industry, Dee Webster May 2023

The Effects Of The Covid-19 Pandemic On Mergers And Acquisitions, Goodwill, And Goodwill Impairment In The Technology Industry, Dee Webster

Honors Scholar Theses

I explore associations between COVID-19 and changes in mergers and acquisitions (M&As), goodwill valuation, and goodwill impairments in the technology industry. Prior literature explores the pandemic’s effects on the dynamics of M&As, goodwill, and goodwill impairment, but are not specific to the pandemic’s impact on the technology industry. This study references prior literature to provide conceptual support as well as research findings to examine the overall changes in technology companies of interest in this study. First, I find that M&A activity before COVID-19 and during COVID-19 was not substantially different when averaged. Second, I find that there was a significant …


Impacts Of Personal Cultural Orientations On College Students’ Psychological Health And Preventive Behaviors During The Covid-19 Period, Joanna Ouyang May 2023

Impacts Of Personal Cultural Orientations On College Students’ Psychological Health And Preventive Behaviors During The Covid-19 Period, Joanna Ouyang

Honors Theses

The COVID-19 pandemic has brought dramatic life changes to individuals across the world. Personal cultural orientations of these individuals alter the way individuals respond to the pandemic and their mental wellness. This research investigates how personal cultural orientations impact college students’ mental health primarily anxiety, prevention behaviors and intentions to reduce the spread of COVID-19, and active coping strategies during the COVID-19 pandemic. Participants (n=155) completed measures of independence, ambiguity intolerance, masculinity, gender equality, mental health, prevention behaviors to reduce the spread of COVID-19, and active coping strategies to protect themselves during the pandemic. Results revealed that people with higher …