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Genomic Evaluation Of Male Reproductive Adaptations And Responses To Dehydration In Peromyscus Eremicus (Cactus Mouse), Lauren Kordonowy

Doctoral Dissertations

Research elucidating the genetic architecture of physiological mechanisms enabling survival and reproduction in extreme environments is becoming prominent in evolutionary biology. The desert, in particular, poses numerous challenges for its endemic species, and mammals (and often, rodents) have been the focus for survival adaptations pertaining to water-limitation. However, desert rodent adaptation research has focused predominantly on survival, while potential physiological reproductive adaptations to dehydration have received less attention, aside from research evaluating water as reproductive cue. The fact that we do not know the physiological mechanisms enabling reproduction during dehydration is surprising, as desert rodents must possess adaptations to successfully …

Full Issue: Volume 10, Number 2

The Science Journal of the Lander College of Arts and Sciences

No abstract provided.

Full Issue: Volume 11, Number 1

The Science Journal of the Lander College of Arts and Sciences

No abstract provided.

Development Of Novel Bio- And Heterogeneous Catalysts For The Production Of Bio- And Green Diesel, Ye Deng

Doctoral Dissertations

Diminishing petroleum reserves and increasing environmental awareness has led to an urgent need to develop alternative fuels, such as biodiesel. Enzymatic trans/-esterification of waste cooking oils with a lipase catalyst is a promising environmentally-friendly process to produce biodiesel, compared to the current industrial chemical process. Despite several advantages, there are a few technical and economical obstacles that limit this process, such as insufficient availability of large quantities of inexpensive lipase suitable for catalysis, and bad performance at low temperatures due to biodiesel’s low cetane number. These limitations are addressed in this dissertation using genetic engineering of plants to produce the …

Workbooks For Instruction In Diagram Comprehension: High School Biology Part I, Jennifer G. Cromley, Tony Perez, Bradley W. Bergey

STEMPS Faculty Publications

Four methods were developed for teaching high school students how to better understand the diagrams in their biology textbooks. The 4 workbooks instantiate these methods: Conventions of Diagrams, Self-Explanation in Diagrams, Student-Completed Diagrams-Visual, and Student-Completed Diagrams-Verbal.

The Intersection Of Contract Law, Reproductive Technology, And The Market: Families In The Age Of Art, Deborah Zalesne

University of Richmond Law Review

No abstract provided.

Uniform Rules: Addressing The Disparate Rules That Deny Student-Athletes The Opportunity To Participate In Sports According To Gender Identity, Chelsea Shrader

University of Richmond Law Review

No abstract provided.

Effects Of The Biomedical Bleeding Process On The Behavior And Physiology Of The American Horseshoe Crab, Limulus Polyphemus, Meghan Owings

Master's Theses and Capstones

Horseshoe crabs are harvested by the biomedical industry in order to create Limulus Amebocyte Lysate (LAL) to test medical devices, vaccines and pharmaceutical drugs for pathogenic gram-negative bacteria. Previous studies of the impacts of the biomedical bleeding process on horseshoe crabs have primarily focused on mortality rates and sublethal impacts, using animals held in the laboratory. Therefore, the first goal of this project was to determine the effects of the bleeding process on horseshoe crab behavior once they are released back into their natural environment. In addition, previous studies have typically only investigated the impacts of the full bleeding procedure, …

No-Boundary Thinking In Bioinformatics, Jason H. Moore, Steven F. Jennings, Casey S. Greene, Lawrence E. Hunter, Andy D. Perkins, Clarlynda Williams-Devane, Donald C. Wunsch, Zhongming Zhao, Xiuzhen Huang

Electrical and Computer Engineering Faculty Research & Creative Works

The following sections are included:
Bioinformatics is a Mature Discipline
The Golden Era of Bioinformatics Has Begun
No-Boundary Thinking in Bioinformatics
References

Determinants Of Host Use In Tachinid Parasitoids (Diptera: Tachinidae) Of Stink Bugs (Hemiptera: Pentatomidae) In Southwest Ohio, Matthew W. Duncan

Browse all Theses and Dissertations

Tachinid parasitoids in the subfamily Phasiinae are important natural enemies of heteropteran bugs. Host location by these flies occurs via antennal reception to the pheromones of their hosts; however little is known regarding the mechanisms which underlie host selection. Halyomorpha halys, the invasive brown marmorated stink bug, represents a potential novel host species in North America. This study was conducted to determine the suitability of H. halys as a host for phasiine species, and to assess cues used in host selection by the species Gymnoclytia occidua. Field attraction to pentatomid pheromones by both phasiines and pentatomids in Southwest Ohio were …

A Novel System For Detection Of Dna Double Strand Breaks And Repair In Human Cells, Todd Warren Lewis

Browse all Theses and Dissertations

Imperative to genomic stability is the ability of the cell to repair damaged DNA which can occur from numerous endogenous byproducts of metabolism or exogenous components from the environment. The Fanconi anemia pathway is a DNA repair mechanism used by human cells to resolve multiple forms of DNA damage including interstrand crosslinks (ICL). Fanconi anemia (FA) is an autosomal recessive inherited disorder characterized by genome instability, developmental abnormalities, cancer predisposition and bone marrow failure. FA is attributed to a mutations in at least 18 genes (FANCA-FANCT) that play a concerted role in DNA repair. FANCT is the latest discovery in …

The Impact Of Socs1 And Socs3 Peptide Mimetics On Rho And Cdc42 Proteins Expression, F-Actin Cytoskeleton Rearrangements, And Cytokines Production Of Uninfected And Hsv-1 Infected M1 And M2 Raw 264.7 Murine Macrophages, Maha A. Elwardany

Browse all Theses and Dissertations

The immune system plays an essential role in the pathogenesis of HSV-1 during the lytic phase of the disease, orchestrating the inflammatory response, retaining the virus in its latent phase and preventing the recurrence of HSV-1 infection. Macrophages display a vital role in the innate and adaptive immune responses during multiple phases of HSV-1 infection. Polarized macrophages are categorized into two distinct classes with diverse functions. The classically activated M1 can engulf and destroy the microbial agents, produce proinflammatory cytokines, and participate in the pathogenesis of many inflammatory diseases. The alternatively activated M2 induces anti-inflammatory mediators and stimulates tissue remodeling …

Pursuing The "Half Empty Question": Biology Undergraduates' Differential Engagement In A Brief Relevance Writing Intervention, Ting Dai, Avi Kaplan, Ying Wang, Jennifer G. Cromley, Tony Perez, Kyle R. Mara, Michael Balsai

STEMPS Faculty Publications

Whereas relevance-writing interventions have shown effects on students’ achievement, a persistent finding is that interventions benefit students with low, but not high, outcome expectancies—a phenomenon that Schwartz et al. (2016) termed the half empty question. In the current mixed-methods study, we investigated the role of undergraduate students’ patterns of engagement in a relevance-writing intervention and their relations to biology course achievement. Ninety-six students who were administered four relevance writing assignments were found to manifest two patterns: Students who completed at least 50% of the intervention in a timely manner outperformed those who completed less-then-50% or completed it late, regardless of …

The Effect Of Arginine Vasotocin On Cryoprotectant Production During Freezing In The Pacific Chorus Frog, Pseudacris Regilla, Ben Ingels

All Master's Theses

Freeze Tolerance is an adaptation seen amongst several species of amphibians as a way of surviving during wintering months. Use of cryoprotectants is seen in all freeze tolerant species (glucose/glycerol). Synthesis and transportation mechanisms that regulate this process are not yet fully understood. Arginine vasotocin is a neurohypophyseal peptide known to have glycogenolytic effects as well as regulate several key processes involved in fluid and solute transportation. Although one prior study suggested that AVT is not involved in responses to freezing, I measured AVT levels during freezing and injected an AVT antagonist to see if it would affect the production …

Actaea Racemosa: The Slender Wands Of Flowering Common Black Cohosh Beckon Us To Explore Woodlands, W. John Hayden

Biology Faculty Publications

Common Black Cohosh is a perennial rhizomatous forest herb. Its horizontal rhizomes bear numerous adventitious roots on the underside and aerial stems of annual duration on the upper side, along with knobby scars left from aerial stems of previous years. Leaves are alternate, twice or thrice compound in ternate or pinnate patterns, and large—up to 1 m long. Individual leaflet size and shape vary with position in the large compound leaves, with position of a leaf on the stem, and from population to population. Most often leaflets are coarsely serrate, lobed to deeply incised, with a truncate to cuneate base …

Existence As Economy And As Charity An Essay On The Essence Of Christianity (1916) By: Antonio Caso, Antonio Caso, Alexander V. Stehn, Jose G. Rodriguez Jr.

Psychological Science Faculty Publications

Antonio Caso rejects the effort of biologists to reduce life to the organic world, a sphere of existence that is defined by economy and egoism, best summarized in the formula: Life = Minimum Effort x Maximum Gain. The problem is that this cannot explain what he calls “disinterested activity,” such as play, art, and self-sacrifice. His primary example of disinterested or selfless activity is the life of Jesus, which Caso also believes is the height of human dignity. In other words, Caso not only argues that there is more than one order of life or existence; he also argues …

Energy Budget For The African Cichlid, Tropheus Duboisi, Cortney Kay Morris

Browse all Theses and Dissertations

Herbivorous fish living in Lake Tanganyika rely on algae as their main source of food and are constantly feeding on low quality (low energy) food. The lake is warming leading to fewer nutrient upwelling’s that are likely limiting the amount of energy available to fish. I calculated an energy budget to compare energy intake against energy expenditure of the African cichlid, Tropheus duboisi, by measuring metabolic rates at rest, while feeding, digesting and being aggressive as well as the caloric content of food, feces, and urine. Fish fed a low quality diet of algae contaminated with sediments had lower growth …

Glycolytic Metabolism And Pregnancy Parameters In The Murine Placenta, Renee Elizabeth Albers

Browse all Theses and Dissertations

The placenta is a complex and essential organ composed largely of fetal-derived cells, including several different trophoblast subtypes that work in unison to support nutrient transport to the fetus during pregnancy. Abnormal placental development can lead to pregnancy-associated disorders that often involve metabolic dysfunction. The scope of dysregulated metabolism during placental development may not be fully representative of the in vivo state in defined culture systems, such as cell lines or isolated primary cells. Thus, assessing metabolic function in intact placental tissue would provide a better assessment of placental metabolism. In this study, we describe a methodology for assaying glycolytic …

The Influence Of Temperature On The Hibernation Patterns And Activity Ofvertigo Moulinsiana (Dupuy, 1849) (Gastropoda: Pulmonata: Vertiginidae), Zofia Ksiazkiewicz Parulska, Katarzyna Pawlak

Turkish Journal of Zoology

The aim of this study was to investigate the impact of different temperatures, i.e. 11 °C and 21 °C, in conditions of medium relative humidity on the rate of awakening of Vertigo moulinsiana after hibernation and its activity during the following 7 days. Oneway ANOVA did not show statistically significant differences in timings of awakening and activity between individuals kept at 11 °C and 21 °C during the first day of the study. The 1-week observations of the activity of V. moulinsiana showed significant differences in relation to temperature. Snails were more active at the lower temperature, which may be …

A New Species Of The Genus Camponotus (Mayr) (Hymenoptera, Formicidae) From Turkey, Celal Karaman, Kadri̇ Kiran, Volkan Aksoy, Yilmaz Çamlitepe

Turkish Journal of Zoology

A new species, Camponotus praegracilis Karaman et Kiran sp. nov. is described; it is a member of the subgenus Tanaemyrmex, from the most species-rich ant genus in Turkey. Some biological notes for the new species are also given. Diagnostic characters of the new species, distinguishing the new species from the most similar species, are also described.

I'Ve Got My Mind Made Up: How Judicial Teleology In Cases Involving Biologically Based Evidence Violates Therapeutic Jurisprudence, Michael L. Perlin

Articles & Chapters

Courts are, and have always been, teleological in cases involving litigants with mental disabilities. By “teleological,” I refer to outcome-determinative reasoning; social science that enables judges to satisfy predetermined positions is privileged, while data that would require judges to question such ends are rejected. In this context, judges treat biologically-based evidence in criminal cases involving questions of mental disability law so as to conform to their pre-existing positions. This applies to cases involving questions of the death penalty, the insanity defense, civil competency, incompetency to stand trial, questions related to malingering, and criminal sentencing, and more.

In this paper, I …

Auranofin Targets Thioredoxin Reductases In Trichomonas Vaginalis, Jose Jauregui

University of the Pacific Theses and Dissertations

Trichomonas vaginalis is an anaerobic, parasitic protozoan, responsible for trichomoniasis, the world’s most common, non-viral sexually transmitted infection. Lacking many of the defenses present in other organisms to combat oxidative stress, Trichomonas vaginalis relies extensively on the thioredoxin system—NADPH, thioredoxin reductase, and thioredoxin—as a means to protect against exposure to excess oxygen. Current trichomoniasis treatment relies exclusively on the 5-nitroimidazole drugs, but fear of drug-resistant strains and allergic reactions to 5-nitroimidazole treatment necessitate the discovery of a new treatment method for trichomoniasis. Previous research has shown that auranofin, an FDA-approved drug, was effective at inhibiting activity of one of Trichomonas …

Studies On Development In Euphilomedes Ostracods: Embryology, Nervous System Development, And The Genetics Of Sexually Dimorphic Eye Development, Kristina Koyama

University of the Pacific Theses and Dissertations

Model organism studies have been fundamental in understanding evolutionary and developmental biology. However, non-model organisms present opportunities to study unique characteristics and as comparisons to model organisms, leading us toward broader and more relevant perspectives on diversity. The Euphilomedes genus of ostracods is an example of a non-model group with potential for evolutionary and developmental studies.

Ostracoda is an ancient, basally branching lineage of Crustaceans with a complete and prodigious fossil record. Despite the group’s promise for evolutionary studies, much remains unknown about the basic biology of this clade. There are a limited number of embryogenesis studies in Ostracoda; here, …

Evaluation Of Oyster Shell Enhancement On Western Snowy Plover Breeding Success, Karine Tokatlian

Master's Theses

The Pacific Coast population of the western snowy plover (Charadrius nivosus nivosus; plover) is listed as a federally threatened species under the U.S. Endangered Species Act due to poor reproductive success from anthropogenic habitat loss, and high predation pressure. Plovers in the South San Francisco Bay use dry salt evaporation ponds, and wildlife-managed ponds, to breed and winter. However, the South Bay Salt Pond Restoration Project aims to restore up to 6,110 hectares of this habitat back to native tidal marsh, which will force plovers to breed in smaller areas and in higher densities. In order to recover plovers in …

Vector Competence Of Aedes Sierrensis And Culex Pipiens Complex (Diptera: Culicidae) For Dirofilaria Immitis (Spirurida: Onchocercidae) In Northern California, Jeffrey Allan Kurosaka

University of the Pacific Theses and Dissertations

Dirofilaria immitis Leidy (dog heartworm) is a life-threatening parasite transmitted by mosquitoes to domestic dogs. Endemic in the eastern United States, cases have become more prevalent over the last few decades. While prevalence in California is generally low, Lake and San Joaquin Counties have reported rates comparable to the East Coast at 3.73% and 0.71%(CAPC 2017), respectively. Aedes sierrensis is thought to be responsible for transmission in California, but in some cases, it exists in inadequate quantities and temporal ranges to explain parasite activity. Based on Huang et al. (2013) and Tran (2016), bloodfeeding patterns, and other vector criteria, Culex …

Dredging Land Reclamation Causing Mucus Development In Massive Spherical Corals In The Spratly Islands, South China Sea: The Effects On China’S Fishing Industry, Tiffany K. Ho

Undergraduate Research Posters

Images from Asia Maritime Transparency Initiative depicted huge masses of white coral mucus secreted from coral reefs in the Spratly Islands of the South China Sea, an area where several land reclamation projects are occurring. The purpose of this research was to understand how increased sedimentation levels from the dredging land reclamation method affects mucus development in massive corals, such as Acropora, located in these reefs. Journal articles that focused on the biology of coral mucus, bacterial communities associated with coral tissue, mucus, and seawater, coral mortality from different environment impacts, coral coverage of reefs in Spratly Islands, and symbiotic …

Separation Of Blood Mixtures Using Fluorescently Labeled Antibodies, Christopher Ehrhardt, Dani Jabado, Emily Brocato

Undergraduate Research Posters

Identifying and analyzing biological mixture samples at a crime scene are of paramount concern for forensic scientists, especially if that type of evidence contains only one cell type. The presence of multiple contributors in a biological evidence sample reduces the probative value of DNA evidence and can sometimes lead to its eventual loss of value. As such, this study was performed in an attempt to examine and evaluate flow cytometry analysis as a means to separate blood mixture samples labeled with fluorescent antibodies. Fluorescein Isothiocyanate (FITC) antibodies were specifically targeted and bound to HLA (Human Leukocyte Antigens) markers present on …

Step By Step: Biology Undergraduates' Problem-Solving Procedures During Multiple-Choice Assessment, Luanna B Prevost, Paula P Lemons

Integrative Biology Faculty and Staff Publications

This study uses the theoretical framework of domain-specific problem solving to explore the procedures students use to solve multiple-choice problems about biology concepts. We designed several multiple-choice problems and administered them on four exams. We trained students to produce written descriptions of how they solved the problem, and this allowed us to systematically investigate their problem-solving procedures. We identified a range of procedures and organized them as domain general, domain specific, or hybrid. We also identified domain-general and domain-specific errors made by students during problem solving. We found that students use domain-general and hybrid procedures more frequently when solving lower-order …

The Science Of Life: Animal Classification, Laura Trumbo

Children's Book and Media Review

The Science of Life: Animal Classification is a reference book that introduces young readers to how scientists classify and organize animals. Without going into depth, Jenny VanVoorst defines important terms like taxonomy, and takes the reader on a brief sampling of the animal kingdom. She begins with taxonomy's founding father, describes all the divisions of animal classification, and ends with explaining where the human reader fits within taxonomy's classification system.

Ecosystem Based Fisheries Management Afs/Ocg 560x, Michael Cerbo

Library Impact Statements

No abstract provided.