Digital Commons Network^™

Adverse Childhood Experiences And The Associations With Depression And Anxiety In Adolescents, Hye Yeon Lee, Isak Kim, Jeongwoon Jeong

Counseling Faculty Publications

Objectives

There has been increasing attention to adverse childhood experiences (ACEs) among adolescents in the U.S because ACEs may result in severe mental health issues. Although associations between ACEs and mental health have been explored, research on how different types or combinations of ACEs render different impacts on adolescents is limited. Therefore, this study aims to (a) examine latent classes of ACEs among adolescents who have experienced at least one ACE and (b) investigate associations of each latent group of ACEs with mental health problems, depression and anxiety.

Method

Questionnaires on ACEs and depression/anxiety from the 2016 National Survey of …

Central Actions Of 3Α,5Α-Thp Involving Nmda And GabaA Receptors Regulate Affective And Sexual Behavior Of Female Rats, Cheryl A. Frye, Alaa Qrareya, Danielle C. Llaneza, Jason J. Paris

Faculty and Student Publications

© Copyright © 2020 Frye, Qrareya, Llaneza and Paris. The neurosteroid, 5α-pregnan-3α-ol-20-one (known as “allopregnanolone” or 3α,5α-THP), is produced in the midbrain ventral tegmental area (VTA), independent of peripheral sources of progestogens, where it has potential actions at N-methyl-D-aspartate (NMDA) and GABAA receptors to facilitate rodent sexual behavior. Progestogens can also have anti-anxiety effects, but whether these involve actions of centrally-derived 3α,5α-THP or these receptors to support reproductively-relevant behavior is not well understood. We investigated the extent to which 3α,5α-THP’s actions via NMDA and/or GABAA receptors in the midbrain VTA influence reproductive behaviors. Estradiol-primed, ovariectomized/adrenalectomized (OVX/ADX) rats received midbrain VTA …

Ethnic Disparity And Exposure To Supplements Rather Than Adverse Childhood Experiences Linked To Preterm Birth In Pakistani Women, Kiran Shaikh, Shahirose Sadrudin Premjib, Sharifa Bashir Lalani, Ntonghanwah Forcheh, Aliyah Dosanic, Ilona S. Yim, Pauline Samia, Christopher Naugler, Nicole Letourneau, The Maternal Infant Global Health Team (Might) Collaborators In Research

Paediatrics and Child Health, East Africa

Background: Adverse childhood experiences (ACEs) are associated with prenatal mental health and negative pregnancy outcomes in high income countries, but whether the same association exists in Pakistan, a low- to middle-income (LMI) country, remains unclear.

Methods: Secondary data analyses of a prospective longitudinal cohort study examining biopsychosocial measures of 300 pregnant women at four sites in Karachi, Pakistan. A predictive multiple logistic regression model for preterm birth (PTB; i.e., <37 weeks’ gestation) was developed from variables significantly (P < 0.05) or marginally (P < 0.10) associated with PTB in the bivariate analyses.

Results: Of the 300 women, 263 (88%) returned for delivery and were included in the current analyses. The PTB rate was 11.1%. We found no association between ACE and PTB. Mother's …

Self-Rated Religiosity/Spirituality And Four Health Outcomes Among Us South Asians: Findings From The Study On Stress, Spirituality, And Health, Samuel Stroope, Blake Victor Kent, Ying Zhang, Namratha R. Kandula, Alka M. Kanaya, Alexandra E. Shields

Faculty Publications

Almost no research exists on the relationship between religiosity/spirituality (R/S) and health in the US South Asian population. Using data from the joint Study on Stress, Spirituality, and Health and Mediators of Atherosclerosis Among South Asians Living in America Study (MASALA), this article examined associations between self-rated R/S and self-rated health, emotional functioning, trait anxiety, and trait anger in a community-based sample (n = 933) from the Chicago and San Francisco Bay areas. Ordinary least squares regression was used to analyze categorical differences in levels of R/S and ordinal trends for R/S, adjusting for potential confounders. Being slightly or moderately …

The Relationship Between Grit And Selected Personality Measures In Medical Students, Gerald A. Isenberg, Andrew Brown, Jennifer Desantis, Jon Veloski, Mohammadreza Hojat

CRMEHC Faculty Papers

OBJECTIVES: To test the hypothesis that scores on a Grit scale are positively associated with personality measures that are conducive to relationship building (Empathy, Self-Esteem, Activity, and Sociability), but inversely associated with personality measures that are detrimental to interpersonal relationships (Neuroticism-Anxiety, Aggression-Hostility, Impulsive Sensation Seeking, and Loneliness).

METHODS: Convenient sampling was used that included 241 medical students at Sidney Kimmel Medical College at Thomas Jefferson University who participated in this ex post facto research. Validated instruments were used to measure Grit, Empathy, Self-Esteem, Activity, Sociability, Neuroticism-Anxiety, Aggression-Hostility, Impulsive Sensation Seeking, and Loneliness. Bivariate correlations and multivariate regression were used to …

Web-Based Graphic Representation Of The Life Course Of Mental Health: Cross-Sectional Study Across The Spectrum Of Mood, Anxiety, Eating, And Substance Use Disorders., Robin Leora Aupperle, Martin P. Paulus, Rayus Kuplicki, James Touthang, Teresa Victor, Hung-Wen Yeh, Tulsa 1000 Investigators, Sahib S. Khalsa

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Although patient history is essential for informing mental health assessment, diagnosis, and prognosis, there is a dearth of standardized instruments measuring time-dependent factors relevant to psychiatric disorders. Previous research has demonstrated the potential utility of graphical representations, termed life charts, for depicting the complexity of the course of mental illness. However, the implementation of these assessments is limited by the exclusive focus on specific mental illnesses (ie, bipolar disorder) and the lack of intuitive graphical interfaces for data collection and visualization.

OBJECTIVE: This study aimed to develop and test the utility of the Tulsa Life Chart (TLC) as a …

The Factor Structure Of Mental Health: Explanatory & Confirmatory Factor Structure Of Psychological Distress And Psychological Well-Being Measures, Badr El Ansari

BAU Journal - Health and Wellbeing

Psychological distress (PD) is usually based on the level of anxiety and depressive symptoms while psychological well-being (PW) is usually conceptualized as some combination of positive affective states such as happiness, optimism, satisfaction with life, and hope. This paper addresses the question of whether psychological distress and psychological well-being are the opposite poles of the same axis of mental health or independent constructs that should be measured on two independent axes. Methods: The sample consisted of (510) Kuwait University students, (240) males with a mean age of (24.08 ±5.10) and (270) females, with a mean age of (21.68 ±2.70), (f=46.77, …

A Feasibility Study Of Lavender Aromatherapy In An Awake Craniotomy Environment, Kailah Cathey, Nichole Gunyon, Nancy Chung, Nancy Conway, Diane Ames, Maharaj Singh, Amin B. Kassam, Richard A. Rovin

Journal of Patient-Centered Research and Reviews

Purpose: Integrative medicine interventions are needed for awake craniotomies, as many patients experience anxiety. Lavender aromatherapy significantly reduces anxiety or pain in a variety of surgical procedures. This feasibility study used lavender aromatherapy during awake craniotomies to determine the number of patients who would consent and complete the study, the technicality of lavender aromatherapy use, and acceptance by operating room (OR) staff.

Methods: We approached 40 consecutive patients (≥18 years old). Exclusion criteria were pulmonary issues or sensitivity to lavender. Outcome measures in consented patients were enrollment and completion rates, anxiety and pain as measured by the Visual Analog Scale …

Anxiety-Related Issues In Cancer Survivorship, Maresi A. Berry-Stoelzle, Anna C. Mark, Peter Kim, Jeanette M. Daly

Journal of Patient-Centered Research and Reviews

Purpose: The purpose of this qualitative study was to examine patient opinions about anxiety in cancer survivorship, particularly the role of the primary care provider in management of anxiety related to the trajectory of long-term cancer survivorship.

Methods: Respondents to a mass email (N = 22,000) were invited to participate in 1 of 3 institutional review board-approved focus group meetings. Inclusion criteria were being an adult patient older than 25 years of age, having any type of cancer diagnosis, and being at least 18 months from treatment. The following specific issues were discussed: role of the primary care provider …

Sensory Processing Patterns And Internalizing Behaviors In The Pediatric And Young Adult General Population: A Scoping Review, Kasey Kotsiris, Jennifer Westrick, Lauren Little

The Open Journal of Occupational Therapy

Background: While research has largely focused on the relationship between sensory processing patterns and internalizing behaviors (e.g., anxiety, depression) in children with autism spectrum disorder or attention deficit hyperactivity disorder, this relationship is not fully understood among the general population or across development.

Method: This scoping review addressed the following research question: How are sensory processing patterns associated with internalizing behaviors (e.g., anxiety, depression) among children with various conditions as well as typically developing children from birth to 22 years of age?

Results: Since 2005, n = 97 peer-reviewed articles have addressed this topic and were included …

Acceptability, Feasibility, And Efficacy Potential Of A Multimodal Acceptance And Commitment Therapy Intervention To Address Psychosocial And Advance Care Planning Needs Among Anxious And Depressed Adults With Metastatic Cancer, Joanna J. Arch, Joel N. Fishbein, Michelle C. Ferris, Jill L. Mitchell, Michael E. Levin, Elizabeth T. Slivjak, David J. Andorsky, Jean S. Kutner

Psychology Faculty Publications

Background: Adults with metastatic cancer frequently report anxiety and depression symptoms, which may impact health behaviors such as advance care planning (ACP).

Objective: The study leveraged acceptance and commitment therapy (ACT), an evidence-based approach for reducing distress and improving health behaviors, and adapted it into a multimodal intervention (M-ACT) designed to address the psychosocial and ACP needs of anxious and depressed adults with metastatic cancer. The study evaluated M-ACT's acceptability, feasibility, and efficacy potential.

Design: The study was designed as a single-arm intervention development and pilot trial.

Setting/Subjects: The trial enrolled 35 anxious or depressed adults with stage IV cancer …

Bias And The Subsequent Implications On Adhd Diagnosis In School Aged Children, Ruth L. Hein

All Electronic Theses and Dissertations

Attention Deficit Hyperactivity Disorder (ADHD) often goes undiagnosed in girls and women. This phenomenon is due most prominently to the finding that girls and women tend to present primarily internalized symptoms of ADHD. Greater awareness of the internalized symptoms of ADHD in the public eye, and especially in teacher training and certification programs is necessary. Under-diagnosis affects several areas of daily life and healthy development, setting the scene for an adult life dealing with anxiety, depression, maladjustment, and a negative self-perception. Further research into diagnosis, specific subsets of symptoms such as Executive Function deficits and Social-Emotional growth and development will …

Humor As A Moderator Of Neuroticism’S Effect On Psychopathology And Life Satisfaction, Adir Pinchot

Theses and Dissertations

Previous research studies evaluated self-enhancing humor (also referred to as coping humor) as a coping strategy that enables an individual to better manage the negative emotions elicited by external stressors. Research has not, however, adequately considered the role that humor may play for neurotic individuals who are characterized by a propensity to experience stress and negative emotions and are, therefore, more susceptible to developing depression, anxiety, and low life satisfaction. Nor has research adequately explored how self-enhancing humor interacts with the maladaptive form of self-directed humor, namely, self-defeating humor. This study attempts to address these lacunae by analyzing whether self-enhancing …

Implementation Of An Anxiety Screening And Treatment Protocol In Primary Care, Danielle E. Garcia

Student Theses, Dissertations and Capstones

Background: Anxiety is a prevalent problem frequently presenting in the primary care setting in the United States. The lack of routine anxiety screening and evidence-based treatment protocols in the adult primary care setting causes physical, social, and economic consequences.

Purpose: The purpose of this Doctor of Nursing Practice (DNP) evidence-based practice (EBP) quality improvement project was to implement an EBP anxiety screening and treatment protocol for adults in a primary care clinic to increase early identification and improve management of generalized anxiety disorder (GAD).

Theoretical Framework: W. Edwards Deming’s Plan-Do-Study-Act (PDSA) cycle framework was utilized for this project. The PDSA …

The Impact Of Mindfulness-Based Yoga Interventions On Fifth-Grade Students’ Perceived Stress And Anxiety, Alicia Cooper Stapp, Ashley Berry Lambert

Faculty and Student Publications

© IEJEE. With rising pressure and an increase in expected academic performance in schools across the United States, students are experiencing higher levels of stress than ever before. To address this issue, the present study examined the impact of mindfulness-based yoga interventions on fifth-grade students’ perceived stress and anxiety levels through a mixed methods research approach. Quantitative data were collected from students through a pre-and post-questionnaire while qualitative data were garnered through an interview with the classroom teacher. Findings revealed that following the intervention period, students reported a decrease in stress levels (9.29%) and a slight increase in anxiety levels …

Irrational Beliefs, Personality Dysfunction, And Negative Emotional Outcomes, Casey Armata

Theses and Dissertations

This study examined the associations between dimensions of personality dysfunction, irrational beliefs, and negative outcomes (depression, social anxiety, anger). Participants consisted of 560 adults. Irrationality partially mediated the association between negative affect and depression, negative affect and social anxiety, and the associations between antagonism and anger, and disinhibition and anger. Our results conform to predictions of cognitive models of disordered personality, except that we did not find strong support for a unique role for specific sub-types of irrational beliefs.

Analysis Of Tech-Based And Telemental Health Approaches Within The Adolescent And Young Adult Populations Of Rural America, Audrey K. Smeenk

Physician Assistant Scholarly Project Posters

The incidences of depression and anxiety among adolescent and young adult populations are intensifying, and resources remain limited for the management of these diseases within rural America.

• Evaluation on different interventions was completed to assess ease of access, efficacy, and patient adherence with the hope to decrease incidence of disease and increase availability of resources to rural areas.

• Based on the current completed research, there is a predominance of evidence that has shown moderate statistical data and promising outcomes from tech-based mobile applications and telemental health. Statistical evidence supports that technological based interventions are a potential treatment option …

Quality Of Life Of Adults With Chronic Spinal Cord Injury In Mainland China: A Cross-Sectional Study, Fengshui Chang, Haixia Xie, Qi Zhang, Mei Sun, Yuhui Yang, Gang Chen, Huifang Wang, Chengyue Li, Jun Lu

Community & Environmental Health Faculty Publications

Objective: To evaluate the quality of life of patients with chronic spinal cord injury in mainland China.

Design: Cross-sectional study. Subjects: A total of 247 adults ≥ 1 year post-SCI in mainland China.

Methods: The World Health Organization (WHO) Quality of Life Scale Brief Version (WHOQOL-BREF) and the add-on modules on disability-related QoL (WHOQOL-DIS) were used to assess quality of life. Anxiety/depression was measured using the Zung Self-Rating Anxiety/Depression Scale. Quality of life was compared with that of reference populations from China, Korea, the international field trial (23 countries). Multivariate linear regression was conducted to determine the factors that might …

Integrating Acceptance And Commitment Therapy Processes With Information-Processing Theory In Anxious Early Adolescents, Gilly Kahn

Theses and Dissertations

The social information-processing (I-P) model states that cognition assumes several cognitive steps (encoding, interpretation, response access, and selection). It has been shown that anxious youth display deficits or distortions at various stages of the social I-P model. In response to ambiguous situations, they show threat perception and interpretation biases, choose maladaptive responses, and engage in greater levels of avoidance than do non-anxious youth. Acceptance and Commitment Therapy (ACT) is an empirically-supported treatment for anxious youth. It aims to increase mindfulness, acceptance, and cognitive defusion, and to decrease experiential avoidance. The mechanisms explaining the effectiveness of ACT processes suggest that they …

Trait Anxiety And Other Personality Constructs As Predictors Of Negative Reactions To Quarantine And Social Isolation, Faith A. Ambrose

Honors Undergraduate Theses

Former research has shown a strong relationship between anxiety and various negative reactions to trauma, including widespread traumatic events such as natural disasters, war, and pandemics. COVID-19 has been an ongoing, potentially traumatic event for individuals all over the world. Even individuals who have not experienced serious traumatic consequences because of the pandemic have likely had some negative experiences regarding the mandated quarantine and social distancing. This study seeks to find possible personality predictors for negative reactions, whether they be behavioral or cognitive. Participants completed several questionnaires that test personality constructs, including trait anxiety, need for affiliation, extraversion, and autonomy. …

Psilocybin-Assisted Psychotherapy: Treating Depression And Anxiety With Mushrooms, Sofia Beck

Physician Assistant Studies | Student Authored Articles

Depression and anxiety are debilitating mental health conditions that affect a large portion of the United States. Current pharmacological treatments for these disorders require daily administration, are associated with a number of side effects, and can be ineffective for some. Emerging evidence in novel treatment options may necessitate a shift toward how we treat these psychiatric disorders.

Studies involving the psychedelic serotonin agonist, psilocybin, are currently experiencing a resurgence as an alternative for patients who are unresponsive to traditional treatments. Clinical trials using psilocybin in combination with psychotherapy have demonstrated sustained reductions in depression and/or anxiety symptoms. When used in …

Impact Of Status-Based Rejection Sensitivity On Depression And Anxiety Symptoms In Gay Men, J. Simowicz, Jedidiah Siev, P. M. Brochu

Psychology Faculty Works

Status-based rejection sensitivity refers to the anxious expectation and tendency to perceive rejection in ambiguous social scenarios based on one’s minority identification. This study evaluates the implications of sensitivity to rejection based on sexual orientation identity on negative mental health outcomes. Current minority stress models include rejection sensitivity as a factor that may contribute to adverse negative psychosocial outcomes in LGBT persons. This study evaluates the role of rejection sensitivity alongside demographically relevant predictors such as age, race, education, and level of sexuality disclosure in predicting the presence of significant depression and anxiety scores among a sample of gay men. …

Associations Between Sleep And In-Race Gastrointestinal Symptoms: An Observational Study Of Running And Triathlon Race Competitors, Patrick Benjamin Wilson

Human Movement Studies & Special Education Faculty Publications

OBJECTIVE: It remains unstudied whether poor sleep is involved in the etiology of gastrointestinal (GI) problems in athletes.

METHODS: Eighty-seven running and triathlon/duathlon race (>60 minutes) participants completed questionnaires to quantify the Sleep Problems Index-(SPI)-I and sleep parameters from the night before races. For GI symptoms, participants reported the severity (0-10 scale) of four upper and three lower symptoms during races. Spearman's correlations examined whether sleep measures were associated with in-race GI symptoms. Partial correlations were calculated to control for age, resting GI symptoms, and anxiety.

RESULTS: SPI-I scores correlated with in-race upper GI symptoms (rho=0.26, p=0.013). Controlling for …

Weighted Blankets: Impact On Prn Medication Use In The Inpatient Mental Health Setting Review Of Literature, Catherine Andela-Ruth

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Introduction: Weighted Blankets (WBs) are a non-pharmacological treatment that can be used to reduce anxiety, agitation, and insomnia in the inpatient mental health (MH) setting. Typically, as-needed (PRN) medications are used first-line with these symptoms. The addition of PRN medications to scheduled medications can cause drug-drug interactions, dependency, adverse side effects, increased healthcare costs and reduced medication compliance. Evidence Summary: WBs are a sensory based intervention (SBI) that provides deep pressure stimulation (DPS). DPS, an evidence-based intervention, has shown to reduce stress symptoms and increase calming symptoms. WBs are a form of DPS used in the inpatient MH setting. WBs …

Recognizing And Addressing Mathematics Anxiety In Female Students, Amanda Sost

West Chester University Master’s Theses

Mathematics anxiety is a prevalent concern in the world of education. As a female mathematician myself, my own personal experiences led me to research the reasons why mathematics anxiety affects more girls than boys. Specifically this paper explores the basics of anxiety including its definition and causes. This definition provides a meaning behind discussing the authoritarian model of education and the importance behind creating a free democratic society, not only in the classroom but in the world. Specifically, the authoritarian style of pedagogy has many affects on students who are learning mathematics, which will be explored as one of the …

College Students' Social Media Uses And Affective Correlates, Jennifer L. Lippold

Graduate Student Theses, Dissertations, & Professional Papers

Given the high prevalence of mental health conditions such as depression and anxiety among college students, research on social media use, a salient feature of the modern college experience, is increasingly warranted. While research documents a link between negative psychological symptomology and social media use, few studies have examined what specific patterns of use may be more or less harmful than others. Therefore, the present study investigated whether specific types of social media use (socially oriented uses, information seeking uses, and entertainment uses) are more or less strongly associated with affective variables (depression, anxiety, positive affect, and negative affect). Utilizing …

Sleep, Experiential Avoidance, And Mental Health Symptoms, Anthony Reffi

Graduate Research Theses & Dissertations

The explanatory mechanisms by which sleep disturbances promote psychopathology are not well understood. Given that poor sleep promotes a broad range of negative emotions the next day, sleep disturbances may increase the tendency to identify inner experiences as aversive, thereby promoting experiential avoidance (EA). Though temporarily effective, the frequent and rigid use of EA has been shown to worsen mental health. Therefore, using a seven-day ecological momentary assessment design, this study investigated momentary EA as a mechanism linking subjective sleep quality and quantity with subsequent anxiety and depressive symptoms. Undergraduate participants (N = 86, Mage = 19.72) first completed an …

An Examination Of Reassurance-Seeking In Relation To Scrupulosity And Contamination Concerns, Katie H. Mangen

Graduate Research Theses & Dissertations

Reassurance-seeking is a safety-seeking behavior that has been observed across symptom dimensions of obsessive-compulsive disorder (OCD), including in individuals with scrupulosity, or moral/religious-based OCD. The current study sought to build upon existing literature by providing an examination of reassurance-seeking in the context of scrupulosity as com- pared with contamination concerns, which represent a different symptom dimension of OCD. Participants (N = 63) completed a battery of questionnaires prior to and following an administration of the Sentence Task—a laboratory-based task intended to elicit distress relevant to an obsessive belief known as thought-action fusion. The study utilized the TRSS-PM, a newly adapted …

Thought-Action Fusion: Comparative Relationship With Symptoms Of Obsessive-Compulsive Disorder And Eating Disorders, Samuel Cares

Graduate Research Theses & Dissertations

There are many similarities between the presentations of individuals with Obsessive-Compulsive Disorder (OCD) and individuals with eating pathology. These include similar obsessive thoughts, repetitive actions, and shared personality characteristics, such as perfectionism. However, similarities may extend beyond that of DSM-based symptomatology to include an important cognitive process called thought-action fusion (TAF). Thought-action fusion is a construct derived from the OCD literature wherein individuals feel that there may be a connection between their thoughts and real-world outcomes. There has been considerable research illustrating the impact TAF has on individuals with OCD, both in terms of development and maintenance of obsessions and …

The Gut-Brain Axis: Treating Depression Through Microbiome Alterations, Alexandria Bachman-Williams

Physician Assistant Scholarly Project Posters

• The purpose of this study is to explore the role of gut microbiome alterations in the treatment of anxiety and depression. • There are multiple pathological pathways that lead to the development of anxiety and depression. • Research shows a link between pathologic bacteria and low grade inflammation. This causes a disruption of neurotransmitters that are current targets of pharmacological treatment of depression and anxiety. • Transfer of “pathogenic” bacteria caused increased symptoms of anxiety and depression. • Treatment with probiotics and “protective” bacteria showed decreased BDI scores and improved symptoms. • Studies were small but show need for …